NIBR189
SMILES | COC1=CC=C(C=C1)C(=O)N2CCN(CC2)C(=O)/C=C/C3=CC=C(C=C3)Br |
InChIKey | OFHXXBRBGWUOHR-NYYWCZLTSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 428.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GPR183 | GP183 | Human | A orphans | A | pIC50 | 7.96 | 7.96 | 7.96 | Guide to Pharmacology |
GPR183 | GP183 | Mouse | A orphans | A | pIC50 | 7.82 | 7.82 | 7.82 | Guide to Pharmacology |
GPR183 | GP183 | Mouse | A orphans | A | pIC50 | 7.82 | 7.84 | 7.86 | ChEMBL |
GPR183 | GP183 | Human | A orphans | A | pIC50 | 7.96 | 8.45 | 9.65 | ChEMBL |