latanoprostene bunod


SMILES O[C@@H](CCc1ccccc1)CC[C@H]1[C@H](O)C[C@@H]([C@@H]1C/C=C\CCCC(=O)OCCCCO[N+](=O)[O-])O
InChIKey LOVMMUBRQUFEAH-UIEAZXIASA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 18
Molecular weight (Da) 507.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pEC50 9.04 9.04 9.05 ChEMBL
ghrelin GHSR Human Ghrelin A pIC50 5.52 6.96 7.7 ChEMBL
ghrelin GHSR Rat Ghrelin A pEC50 8.52 8.52 8.52 ChEMBL