flupentixol


SMILES OCCN1CCN(CC1)CC/C=C\1/c2ccccc2Sc2c1cc(cc2)C(F)(F)F
InChIKey NJMYODHXAKYRHW-DVZOWYKESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 434.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations D1 D2 D5

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CysLT2 CLTR2 Human Leukotriene A pIC50 5.74 5.74 5.74 Guide to Pharmacology
CysLT1 CLTR1 Human Leukotriene A pIC50 9.0 9.0 9.0 Guide to Pharmacology