octopamine


SMILES NCC(c1ccc(cc1)O)O
InChIKey QHGUCRYDKWKLMG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 153.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pEC50 4.8 5.3 5.8 Guide to Pharmacology
TA1 TAAR1 Rat Trace amine A pEC50 5.9 5.9 5.9 Guide to Pharmacology
TA1 TAAR1 Mouse Trace amine A pEC50 5.4 5.6 5.8 Guide to Pharmacology
TA1 TAAR1 Rat Trace amine A pEC50 5.89 5.89 5.89 ChEMBL
TA1 TAAR1 Human Trace amine A pEC50 8.24 8.24 8.24 Drug Central
TA1 TAAR1 Rat Trace amine A pEC50 8.23 8.23 8.23 Drug Central
TA1 TAAR1 Mouse Trace amine A pEC50 8.24 8.24 8.24 Drug Central