octopamine
SMILES | NCC(c1ccc(cc1)O)O |
InChIKey | QHGUCRYDKWKLMG-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 3 |
Rotatable bonds | 2 |
Molecular weight (Da) | 153.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Endogenous |
Approved drug | Yes |
Database connections
Ligand site mutations | α2A |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT7 | 5HT7R | Rat | 5-Hydroxytryptamine | A | pKi | 6.0 | 6.0 | 6.0 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
TA1 | TAAR1 | Human | Trace amine | A | pEC50 | 4.8 | 5.3 | 5.8 | Guide to Pharmacology |
TA1 | TAAR1 | Rat | Trace amine | A | pEC50 | 5.9 | 5.9 | 5.9 | Guide to Pharmacology |
TA1 | TAAR1 | Mouse | Trace amine | A | pEC50 | 5.4 | 5.6 | 5.8 | Guide to Pharmacology |
TA1 | TAAR1 | Rat | Trace amine | A | pEC50 | 5.89 | 5.89 | 5.89 | ChEMBL |
TA1 | TAAR1 | Human | Trace amine | A | pEC50 | 8.24 | 8.24 | 8.24 | Drug Central |
TA1 | TAAR1 | Rat | Trace amine | A | pEC50 | 8.23 | 8.23 | 8.23 | Drug Central |
TA1 | TAAR1 | Mouse | Trace amine | A | pEC50 | 8.24 | 8.24 | 8.24 | Drug Central |