CHEMBL2381650


SMILES N[C@@]1(C(=O)O)C[C@@H](Sc2ccccc2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey QMTVYANBFIIHRR-SEKJGCFDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 293.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.86 6.86 6.86 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.38 6.38 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Human Metabotropic glutamate C pEC50 5.9 5.9 5.9 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.11 5.71 6.05 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 5.15 5.16 5.16 ChEMBL