HARMINE


SMILES COc1ccc2c(c1)[nH]c1c(C)nccc12
InChIKey BXNJHAXVSOCGBA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 212.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.95 5.95 5.95 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.09 6.09 6.09 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.26 5.26 5.26 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.59 5.59 5.59 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.83 5.83 5.83 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.03 5.03 5.03 ChEMBL
5-HT2C K7GSR7 Pig 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT1D F1MMU1 Bovine 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database