LY2389575
SMILES | Clc1ccc(c(c1)Cl)CN[C@H]1CCN(C1)c1ncc(cn1)Br |
InChIKey | PXQNLQLMRMROSB-ZDUSSCGKSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 1 |
Rotatable bonds | 4 |
Molecular weight (Da) | 400.0 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
mGlu3 | GRM3 | Human | Metabotropic glutamate | C | pIC50 | 6.72 | 6.72 | 6.72 | Guide to Pharmacology |
mGlu3 | GRM3 | Human | Metabotropic glutamate | C | pIC50 | 5.38 | 5.83 | 6.72 | ChEMBL |
mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pIC50 | 4.77 | 4.77 | 4.77 | ChEMBL |