CHEMBL2387193


SMILES O=C1Cc2ccccc2N1C1CCN(C2CC[C@H]3CCCc4cccc2c43)CC1
InChIKey SZKWDIATUVLAAW-PHSANKKPSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.94 7.94 7.94 ChEMBL
κ OPRK Human Opioid A pKi 6.17 6.17 6.17 ChEMBL
μ OPRM Human Opioid A pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.34 7.34 7.34 ChEMBL
μ OPRM Human Opioid A pEC50 6.89 6.89 6.89 ChEMBL