CHEMBL27251


SMILES CN1CCc2ccc3c4c2[C@H]1Cc1cccc(c1-4)[C@@H]3N
InChIKey DAKGDRVNCPHAPY-KDOFPFPSSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 262.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.43 6.43 6.43 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.03 7.03 7.03 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.65 5.65 5.65 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.65 5.65 5.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database