PAF
SMILES | CCCCCCCCCCCCCCCCOC[C@@H](OC(=O)C)COP(=O)(OCC[N+](C)(C)C)[O-] |
InChIKey | HVAUUPRFYPCOCA-AREMUKBSSA-N |
Chemical properties
Hydrogen bond acceptors | 7 |
Hydrogen bond donors | 0 |
Rotatable bonds | 25 |
Molecular weight (Da) | 523.4 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Endogenous |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
PAF | PTAFR | Human | Platelet-activating factor | A | pKi | 7.5 | 7.7 | 7.9 | Guide to Pharmacology |
PAF | PTAFR | Human | Platelet-activating factor | A | pKd | 8.8 | 8.85 | 8.9 | Guide to Pharmacology |
PAF | PTAFR | Human | Platelet-activating factor | A | pKi | 9.82 | 9.82 | 9.82 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
PAF | PTAFR | Human | Platelet-activating factor | A | pIC50 | 8.2 | 8.2 | 8.2 | Guide to Pharmacology |
PAF | PTAFR | Human | Platelet-activating factor | A | pIC50 | 9.55 | 9.55 | 9.55 | ChEMBL |