CHEMBL240774


SMILES O=C1c2ccccc2CN1CCCCN1CCN(c2ccccc2)CC1
InChIKey SEAGRPUHJMFFQR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.45 7.45 7.45 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.72 6.97 7.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database