L-159913


SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)cc1
InChIKey JVOGASLNIGJLLS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 634.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pKi 8.77 8.77 8.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTRB Rat Angiotensin A pIC50 9.48 9.5 9.51 ChEMBL
AT2 AGTR2 Rat Angiotensin A pIC50 6.35 6.5 6.57 ChEMBL
AT1 AGTR1 Rabbit Angiotensin A pIC50 6.3 8.96 9.37 ChEMBL
AT1 AGTR1 Human Angiotensin A pIC50 8.6 8.6 8.6 ChEMBL