CHEMBL283036


SMILES FC(F)(F)c1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1
InChIKey BFQIOOYNLCWKIJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.47 7.47 7.47 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.15 5.15 5.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.55 5.55 5.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database