Ligand source activities (1 row/activity)



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Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
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name		 GPCRdb
ID		 #Vendors

 Reference
ligand		 Fold
selectivity		 # Tested
GPCRs		 Species

 p-value
(-log)		 Activity
Type		 Activity
Relation		 Activity
Value		 AssayType

 Assay
Description		 Source

 Mol
weight		 Rot
Bonds		 H don

 H acc

 LogP

 Smiles

 DOI
4157793 47272 8 None - 1 Human 5.0 pIC50 = 5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 417 5 2 8 2.7 COc1ccc(C2=NN(c3nc(C(=O)O)cs3)C(O)(C(F)(F)F)C2)c(OC)c1 nan
CHEMBL1543980 47272 8 None - 1 Human 5.0 pIC50 = 5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 417 5 2 8 2.7 COc1ccc(C2=NN(c3nc(C(=O)O)cs3)C(O)(C(F)(F)F)C2)c(OC)c1 nan
2368939 55499 9 None 1 2 Human 5.0 pIC50 = 5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 2 0 2 6.0 CC(C)(C)c1ccc(-c2c[n+](-c3ccc(Br)cc3)c3n2CCCS3)cc1 nan
CHEMBL1416660 55499 9 None 1 2 Human 5.0 pIC50 = 5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 2 0 2 6.0 CC(C)(C)c1ccc(-c2c[n+](-c3ccc(Br)cc3)c3n2CCCS3)cc1 nan
CHEMBL1620142 55499 9 None 1 2 Human 5.0 pIC50 = 5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 2 0 2 6.0 CC(C)(C)c1ccc(-c2c[n+](-c3ccc(Br)cc3)c3n2CCCS3)cc1 nan
842058 28676 17 None - 1 Human 6.0 pIC50 = 6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 343 4 0 4 3.0 Cc1nn(C)c(C)c1CN(C)S(=O)(=O)c1ccc2ccccc2c1 nan
CHEMBL1377607 28676 17 None - 1 Human 6.0 pIC50 = 6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 343 4 0 4 3.0 Cc1nn(C)c(C)c1CN(C)S(=O)(=O)c1ccc2ccccc2c1 nan
3006170 59548 7 None -2 3 Human 6.0 pIC50 = 6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 325 3 5 9 -1.7 NC(=S)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 nan
CHEMBL171699 59548 7 None -2 3 Human 6.0 pIC50 = 6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 325 3 5 9 -1.7 NC(=S)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 nan
2323706 39136 6 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 314 8 1 4 3.5 CC(C)CCOc1cccc(OCC(=O)Nc2ccncc2)c1 nan
CHEMBL1469379 39136 6 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 314 8 1 4 3.5 CC(C)CCOc1cccc(OCC(=O)Nc2ccncc2)c1 nan
53385430 88764 0 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 5 0 4 4.2 Fc1ccc(CN2CCN(c3ncc(Cc4ccccc4)cn3)CC2)c(Cl)c1 nan
CHEMBL2362703 88764 0 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 5 0 4 4.2 Fc1ccc(CN2CCN(c3ncc(Cc4ccccc4)cn3)CC2)c(Cl)c1 nan
4544702 47521 2 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 448 6 1 5 5.9 O=C(Nc1nc(-c2ccc(Cl)cc2Cl)cs1)c1ccc(OCC2CCCO2)cc1 nan
CHEMBL1545848 47521 2 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 448 6 1 5 5.9 O=C(Nc1nc(-c2ccc(Cl)cc2Cl)cs1)c1ccc(OCC2CCCO2)cc1 nan
3932658 59407 7 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 5 1 7 1.3 NC(=O)c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2)c([N+](=O)[O-])c1 nan
CHEMBL1709973 59407 7 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 5 1 7 1.3 NC(=O)c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2)c([N+](=O)[O-])c1 nan
44825951 67574 0 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 376 13 1 4 4.6 CCCCC[C@@H](/C=C/C1C(=O)C=C[C@H]1C/C=C\CCCC(=O)O)OC(C)=O nan
CHEMBL1899895 67574 0 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 376 13 1 4 4.6 CCCCC[C@@H](/C=C/C1C(=O)C=C[C@H]1C/C=C\CCCC(=O)O)OC(C)=O nan
729558 197698 11 None 1 2 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 233 3 0 6 1.1 CCOc1nc(C#N)nc(N2CCCCC2)n1 nan
CHEMBL571295 197698 11 None 1 2 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 233 3 0 6 1.1 CCOc1nc(C#N)nc(N2CCCCC2)n1 nan
10662 127518 27 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 398 3 2 4 3.7 O=C(C(=O)c1cc(Br)ccc1O)c1cc(Br)ccc1O nan
CHEMBL366205 127518 27 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 398 3 2 4 3.7 O=C(C(=O)c1cc(Br)ccc1O)c1cc(Br)ccc1O nan
1155337 42202 4 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 490 8 0 8 4.8 O=C(CSc1nnc(Cn2nnc3ccccc32)o1)N(Cc1ccc(Cl)cc1)c1ccccc1 nan
CHEMBL1497024 42202 4 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 490 8 0 8 4.8 O=C(CSc1nnc(Cn2nnc3ccccc32)o1)N(Cc1ccc(Cl)cc1)c1ccccc1 nan
648690 31505 7 None 1 2 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 354 4 1 4 2.8 Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc(N2CCCC2=O)cc1 nan
CHEMBL1403484 31505 7 None 1 2 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 354 4 1 4 2.8 Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc(N2CCCC2=O)cc1 nan
24791438 59998 6 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 399 6 0 5 3.8 CSc1ccc(C(=O)C2CCCN(C(=O)CCc3c(C)nn(C)c3C)C2)cc1 nan
CHEMBL1734666 59998 6 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 399 6 0 5 3.8 CSc1ccc(C(=O)C2CCCN(C(=O)CCc3c(C)nn(C)c3C)C2)cc1 nan
1952659 40455 14 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 379 5 1 7 3.9 O=C(CSc1nnc(-c2cccnc2)s1)Nc1ccnc2ccccc12 nan
CHEMBL1482468 40455 14 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 379 5 1 7 3.9 O=C(CSc1nnc(-c2cccnc2)s1)Nc1ccnc2ccccc12 nan
16235315 28118 4 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 6 1 4 3.5 CC(CC(=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1)c1ccccc1 nan
CHEMBL1373162 28118 4 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 6 1 4 3.5 CC(CC(=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1)c1ccccc1 nan
992688 34979 12 None 10 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 372 7 0 8 3.3 COc1cc(CSc2nnnn2-c2ccc(C)cc2)cc(OC)c1OC nan
CHEMBL1432721 34979 12 None 10 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 372 7 0 8 3.3 COc1cc(CSc2nnnn2-c2ccc(C)cc2)cc(OC)c1OC nan
6906133 108283 4 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 404 9 1 5 4.0 COc1ccc(/C=N/OCC(=O)NC(c2ccccc2)c2ccccc2)cc1OC nan
CHEMBL3197447 108283 4 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 404 9 1 5 4.0 COc1ccc(/C=N/OCC(=O)NC(c2ccccc2)c2ccccc2)cc1OC nan
4969272 36622 6 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.4 CC(=O)c1ccc(N2CCN(C(S)=Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 nan
CHEMBL1448690 36622 6 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.4 CC(=O)c1ccc(N2CCN(C(S)=Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 nan
647700 47678 8 None 12 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 474 8 0 8 4.3 O=C(CSc1nnc(Cn2nnc3ccccc32)o1)N(Cc1ccc(F)cc1)c1ccccc1 nan
CHEMBL1547232 47678 8 None 12 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 474 8 0 8 4.3 O=C(CSc1nnc(Cn2nnc3ccccc32)o1)N(Cc1ccc(F)cc1)c1ccccc1 nan
2405889 48829 5 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 327 6 1 3 4.5 CC(=O)c1c(C)[nH]c(C(=O)COc2cc(C)ccc2C(C)C)c1C nan
CHEMBL1559053 48829 5 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 327 6 1 3 4.5 CC(=O)c1c(C)[nH]c(C(=O)COc2cc(C)ccc2C(C)C)c1C nan
135521496 88693 5 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 523 6 3 13 1.8 Nc1nonc1-n1nnc(C(=O)N/N=C/c2cc(Br)ccc2O)c1CSC1=NCCS1 nan
CHEMBL2359911 88693 5 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 523 6 3 13 1.8 Nc1nonc1-n1nnc(C(=O)N/N=C/c2cc(Br)ccc2O)c1CSC1=NCCS1 nan
24790899 53434 1 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 367 8 0 5 4.1 C=CCC1(CC=C)CCCN1C(=O)c1cc(COc2ccc(C)nc2)on1 nan
CHEMBL1600776 53434 1 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 367 8 0 5 4.1 C=CCC1(CC=C)CCCN1C(=O)c1cc(COc2ccc(C)nc2)on1 nan
616573 4598 26 None 2 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
CHEMBL102726 4598 26 None 2 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
CHEMBL1444764 4598 26 None 2 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
49778835 67214 0 None - 1 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 388 6 1 5 4.4 COc1ccc(CNC(=O)c2cccc3c(-c4cccnc4)coc23)cc1OC nan
CHEMBL1878609 67214 0 None - 1 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 388 6 1 5 4.4 COc1ccc(CNC(=O)c2cccc3c(-c4cccnc4)coc23)cc1OC nan
984148 46999 4 None -1 3 Human 4.9 pIC50 = 4.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 6 3 6 3.9 CCCc1cc(-c2[nH]ncc2-c2ccc(C(=O)OCC)o2)c(O)cc1O nan
CHEMBL1541596 46999 4 None -1 3 Human 4.9 pIC50 = 4.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 6 3 6 3.9 CCCc1cc(-c2[nH]ncc2-c2ccc(C(=O)OCC)o2)c(O)cc1O nan
16196350 55049 2 None 48 2 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
3253322 55049 2 None 48 2 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
5773522 55049 2 None 48 2 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
CHEMBL1323872 55049 2 None 48 2 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
CHEMBL1616531 55049 2 None 48 2 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
3146673 48018 14 None - 1 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 249 3 1 3 3.8 CC(Nc1ncnc2ccccc12)c1ccccc1 nan
CHEMBL1550278 48018 14 None - 1 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 249 3 1 3 3.8 CC(Nc1ncnc2ccccc12)c1ccccc1 nan
5153 111952 14 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
CHEMBL1584044 111952 14 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
CHEMBL328834 111952 14 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
1878823 197182 11 None 4 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 11 1 2 4.9 CCCCCCCCCCCCn1ccc(=N)cc1 nan
CHEMBL1544561 197182 11 None 4 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 11 1 2 4.9 CCCCCCCCCCCCn1ccc(=N)cc1 nan
CHEMBL568092 197182 11 None 4 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 11 1 2 4.9 CCCCCCCCCCCCn1ccc(=N)cc1 nan
20968904 51563 6 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 469 8 1 5 5.3 Cc1oc(-c2ccc(Cl)cc2)nc1CSCC(=O)NC1CCN(Cc2ccccc2)CC1 nan
CHEMBL1583186 51563 6 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 469 8 1 5 5.3 Cc1oc(-c2ccc(Cl)cc2)nc1CSCC(=O)NC1CCN(Cc2ccccc2)CC1 nan
976991 34145 9 None - 1 Human 4.9 pIC50 = 4.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 331 3 1 5 2.7 NC(=O)c1cn(-c2ccccc2)nc1-c1cc2ccccc2oc1=O nan
CHEMBL1425860 34145 9 None - 1 Human 4.9 pIC50 = 4.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 331 3 1 5 2.7 NC(=O)c1cn(-c2ccccc2)nc1-c1cc2ccccc2oc1=O nan
24817489 24812 2 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 381 6 0 6 3.3 COCC1CCCN(C(=O)c2cc(COc3ccc4ncccc4c3)on2)C1 nan
CHEMBL1344808 24812 2 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 381 6 0 6 3.3 COCC1CCCN(C(=O)c2cc(COc3ccc4ncccc4c3)on2)C1 nan
787494 38064 10 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 276 3 1 2 3.7 Cc1cc(NC(=O)Cc2ccccc2)c2ccccc2n1 nan
CHEMBL1460627 38064 10 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 276 3 1 2 3.7 Cc1cc(NC(=O)Cc2ccccc2)c2ccccc2n1 nan
51360001 88725 0 None - 1 Human 4.9 pIC50 = 4.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 392 3 0 3 6.4 FC(F)(F)c1ccccc1Cc1c(-c2ccco2)nc2c3ccccc3ccn12 nan
CHEMBL2361231 88725 0 None - 1 Human 4.9 pIC50 = 4.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 392 3 0 3 6.4 FC(F)(F)c1ccccc1Cc1c(-c2ccco2)nc2c3ccccc3ccn12 nan
5153 111952 14 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
CHEMBL1584044 111952 14 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
CHEMBL328834 111952 14 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
650985 42479 3 None 2 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 5 1 6 2.4 COc1ccc(CCNc2c(C)c(C)nc3ncnn23)cc1 nan
CHEMBL1499501 42479 3 None 2 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 5 1 6 2.4 COc1ccc(CCNc2c(C)c(C)nc3ncnn23)cc1 nan
404407 60221 2 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 2 0 2 3.4 CN(C)c1ccc(C=c2c3ccccc3n3c2c2c([n+]3C)CCCC2)cc1 nan
5472654 60221 2 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 2 0 2 3.4 CN(C)c1ccc(C=c2c3ccccc3n3c2c2c([n+]3C)CCCC2)cc1 nan
CHEMBL1721330 60221 2 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 2 0 2 3.4 CN(C)c1ccc(C=c2c3ccccc3n3c2c2c([n+]3C)CCCC2)cc1 nan
CHEMBL1740248 60221 2 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 2 0 2 3.4 CN(C)c1ccc(C=c2c3ccccc3n3c2c2c([n+]3C)CCCC2)cc1 nan
2766344 32627 17 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 496 10 0 8 3.6 COC(=O)C1CCN(Cc2ccc(OCCCN3CCN(c4ccc([N+](=O)[O-])cc4)CC3)cc2)CC1 nan
CHEMBL1412887 32627 17 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 496 10 0 8 3.6 COC(=O)C1CCN(Cc2ccc(OCCCN3CCN(c4ccc([N+](=O)[O-])cc4)CC3)cc2)CC1 nan
3306 206261 39 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 181 4 3 3 1.0 CCNCC(O)c1cccc(O)c1 nan
CHEMBL86882 206261 39 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 181 4 3 3 1.0 CCNCC(O)c1cccc(O)c1 nan
2800172 37063 8 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 4 1 4 4.8 CC(C)(C)c1ccc(C(=O)Nc2ccc(Oc3cccnc3)nc2)cc1 nan
CHEMBL1452130 37063 8 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 4 1 4 4.8 CC(C)(C)c1ccc(C(=O)Nc2ccc(Oc3cccnc3)nc2)cc1 nan
9261962 26225 5 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 400 7 0 7 2.6 CC(C)c1ccc(CN2CCN(C(=O)CSc3nnnn3C3CC3)CC2)cc1 nan
CHEMBL1357535 26225 5 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 400 7 0 7 2.6 CC(C)c1ccc(CN2CCN(C(=O)CSc3nnnn3C3CC3)CC2)cc1 nan
49786188 67133 0 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 370 8 2 6 3.7 O=C(Nc1ccc(Oc2ccccc2)cc1)c1csc(COCCO)n1 nan
CHEMBL1875054 67133 0 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 370 8 2 6 3.7 O=C(Nc1ccc(Oc2ccccc2)cc1)c1csc(COCCO)n1 nan
646459 36914 4 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.9 O=C(CN1CCC(c2nc3ccccc3s2)CC1)NCc1cccs1 nan
CHEMBL1451015 36914 4 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.9 O=C(CN1CCC(c2nc3ccccc3s2)CC1)NCc1cccs1 nan
743662 59762 12 None - 1 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 300 2 0 2 4.2 Cc1nc2ccccc2n1Cc1ccc(Br)cc1 nan
CHEMBL1725453 59762 12 None - 1 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 300 2 0 2 4.2 Cc1nc2ccccc2n1Cc1ccc(Br)cc1 nan
1254286 33150 7 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 334 4 1 3 3.5 Cc1cc(OCC(=O)Nc2ccncc2)c(C)cc1Br nan
CHEMBL1417355 33150 7 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 334 4 1 3 3.5 Cc1cc(OCC(=O)Nc2ccncc2)c(C)cc1Br nan
2374706 51418 6 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 501 7 2 6 5.2 COc1ccc(-c2csc(NC(=O)c3ccccc3NS(=O)(=O)c3ccc(F)c(F)c3)n2)cc1 nan
CHEMBL1581949 51418 6 None - 1 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 501 7 2 6 5.2 COc1ccc(-c2csc(NC(=O)c3ccccc3NS(=O)(=O)c3ccc(F)c(F)c3)n2)cc1 nan
2795668 29685 5 None - 1 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 416 2 1 3 4.5 Fc1ccc(N=C(S)N2CCCN(c3ccc(C(F)(F)F)cn3)CC2)c(F)c1 nan
CHEMBL1386344 29685 5 None - 1 Human 6.9 pIC50 = 6.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 416 2 1 3 4.5 Fc1ccc(N=C(S)N2CCCN(c3ccc(C(F)(F)F)cn3)CC2)c(F)c1 nan
655948 26623 7 None 17 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 351 2 0 8 2.4 Cc1cc(N2CCN(c3nc4ccccc4s3)CC2)n2ncnc2n1 nan
CHEMBL1361461 26623 7 None 17 2 Human 5.9 pIC50 = 5.9 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 351 2 0 8 2.4 Cc1cc(N2CCN(c3nc4ccccc4s3)CC2)n2ncnc2n1 nan
24793159 38172 2 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 377 3 1 5 3.7 Cn1nccc1C(=O)NC1CCCc2c1cnn2-c1ccc(C(C)(C)C)cc1 nan
CHEMBL1461631 38172 2 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 377 3 1 5 3.7 Cn1nccc1C(=O)NC1CCCc2c1cnn2-c1ccc(C(C)(C)C)cc1 nan
657154 52116 12 None 6 2 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 467 6 2 5 5.3 Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)Nc2nc(-c3ccc(F)cc3)cs2)cc1 nan
CHEMBL1587630 52116 12 None 6 2 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 467 6 2 5 5.3 Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)Nc2nc(-c3ccc(F)cc3)cs2)cc1 nan
51360013 88692 0 None - 1 Human 4.8 pIC50 = 4.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 434 3 0 3 6.3 Cc1cc(Br)cn2c(Cc3ccccc3C(F)(F)F)c(-c3ccco3)nc12 nan
CHEMBL2359888 88692 0 None - 1 Human 4.8 pIC50 = 4.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 434 3 0 3 6.3 Cc1cc(Br)cn2c(Cc3ccccc3C(F)(F)F)c(-c3ccco3)nc12 nan
1966784 20739 8 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 414 6 2 6 3.9 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NS(=O)(=O)c1ccc(Cl)s1 nan
CHEMBL1309273 20739 8 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 414 6 2 6 3.9 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NS(=O)(=O)c1ccc(Cl)s1 nan
9551471 21795 10 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 478 7 1 7 2.6 CCCCCn1c(=O)[nH]c2cc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)ccc2c1=O nan
CHEMBL1319304 21795 10 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 478 7 1 7 2.6 CCCCCn1c(=O)[nH]c2cc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)ccc2c1=O nan
24819530 47307 0 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 395 5 0 7 3.0 COC(=O)C1CCCCN1C(=O)c1cc(COc2cccc3cnccc23)on1 nan
CHEMBL1544190 47307 0 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 395 5 0 7 3.0 COC(=O)C1CCCCN1C(=O)c1cc(COc2cccc3cnccc23)on1 nan
243725 97118 36 None - 1 Human 7.8 pIC50 = 7.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 3 0 6 3.8 COc1cc2c(cc1OC)[C@@H]1C(=O)c3ccc4c(c3O[C@@H]1CO2)C[C@H](C(C)C)O4 nan
CHEMBL267630 97118 36 None - 1 Human 7.8 pIC50 = 7.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 3 0 6 3.8 COc1cc2c(cc1OC)[C@@H]1C(=O)c3ccc4c(c3O[C@@H]1CO2)C[C@H](C(C)C)O4 nan
2795769 26928 5 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 3 1 5 4.9 Cc1c(Cl)cccc1NC(=O)N1CCCN(c2nc(-c3ccccc3)ns2)CC1 nan
CHEMBL1364108 26928 5 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 3 1 5 4.9 Cc1c(Cl)cccc1NC(=O)N1CCCN(c2nc(-c3ccccc3)ns2)CC1 nan
2356907 42464 6 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 343 2 1 3 4.0 Cc1nn(C)c(Nc2ccc(Br)cc2)c1Br nan
CHEMBL1499354 42464 6 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 343 2 1 3 4.0 Cc1nn(C)c(Nc2ccc(Br)cc2)c1Br nan
2537601 44137 6 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 10 2 8 2.0 COc1cc(CCC(=O)OCC(=O)Nc2sccc2C(N)=O)cc(OC)c1OC nan
CHEMBL1515567 44137 6 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 10 2 8 2.0 COc1cc(CCC(=O)OCC(=O)Nc2sccc2C(N)=O)cc(OC)c1OC nan
3155818 43699 8 None 5 2 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 368 8 1 6 3.4 CCCOC(=O)c1ccc(OCC(O)Cn2c(C)nc3ccccc32)cc1 nan
CHEMBL1510261 43699 8 None 5 2 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 368 8 1 6 3.4 CCCOC(=O)c1ccc(OCC(O)Cn2c(C)nc3ccccc32)cc1 nan
1231799 24262 11 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 3 1 3 3.0 Cc1nn(C)c(C(=O)NCc2ccc(Cl)cc2)c1Cl nan
CHEMBL1340112 24262 11 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 3 1 3 3.0 Cc1nn(C)c(C(=O)NCc2ccc(Cl)cc2)c1Cl nan
2318546 59298 8 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 334 6 1 4 4.2 Cc1ccc(Oc2ccc(OCC(=O)Nc3ccncc3)cc2)cc1 nan
CHEMBL1705098 59298 8 None - 1 Human 6.8 pIC50 = 6.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 334 6 1 4 4.2 Cc1ccc(Oc2ccc(OCC(=O)Nc3ccncc3)cc2)cc1 nan
187 255 39 None -22 8 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
294 255 39 None -22 8 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
65 255 39 None -22 8 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
8593 255 39 None -22 8 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
CHEMBL667 255 39 None -22 8 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
DB03128 255 39 None -22 8 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
2349797 27564 8 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 307 4 2 2 3.8 S=C(NCCc1ccccc1)Nc1cccc2cnccc12 nan
CHEMBL1369262 27564 8 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 307 4 2 2 3.8 S=C(NCCc1ccccc1)Nc1cccc2cnccc12 nan
5613808 39295 9 None - 1 Human 4.8 pIC50 = 4.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 214 1 2 5 1.2 O=[N+]([O-])c1[nH]c2nc(O)nc-2cc1Cl nan
CHEMBL1470764 39295 9 None - 1 Human 4.8 pIC50 = 4.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 214 1 2 5 1.2 O=[N+]([O-])c1[nH]c2nc(O)nc-2cc1Cl nan
51360490 67098 0 None - 1 Human 7.8 pIC50 = 7.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 1059 8 1 13 5.2 CC[C@H](C)C1C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](COC)C(=O)N2CCC[C@H]2C(=O)N(C)[C@@H](C(C)C)C(=O)N2CCC[C@H]2C(=O)O[C@H](CC)CCC[C@@H](O)[C@@H](C)C(=O)O[C@H](C)[C@@H](C)C/C=C(C)/C(OC)=C\C(=O)N1C nan
CHEMBL1873644 67098 0 None - 1 Human 7.8 pIC50 = 7.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 1059 8 1 13 5.2 CC[C@H](C)C1C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](COC)C(=O)N2CCC[C@H]2C(=O)N(C)[C@@H](C(C)C)C(=O)N2CCC[C@H]2C(=O)O[C@H](CC)CCC[C@@H](O)[C@@H](C)C(=O)O[C@H](C)[C@@H](C)C/C=C(C)/C(OC)=C\C(=O)N1C nan
2874826 29724 12 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 276 3 1 5 1.5 CC1CC(=O)NN=C1c1ccc(N(C)C)c([N+](=O)[O-])c1 nan
CHEMBL1386646 29724 12 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 276 3 1 5 1.5 CC1CC(=O)NN=C1c1ccc(N(C)C)c([N+](=O)[O-])c1 nan
823638 53778 21 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 278 4 1 3 3.3 O=C(COc1ccc2ccccc2c1)Nc1ccncc1 nan
CHEMBL1603921 53778 21 None - 1 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 278 4 1 3 3.3 O=C(COc1ccc2ccccc2c1)Nc1ccncc1 nan
2426360 46887 6 None 8 2 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 382 3 3 3 4.6 Fc1ccc(N=C(S)NNc2ncc(C(F)(F)F)cc2Cl)c(F)c1 nan
CHEMBL1540808 46887 6 None 8 2 Human 5.8 pIC50 = 5.8 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 382 3 3 3 4.6 Fc1ccc(N=C(S)NNc2ncc(C(F)(F)F)cc2Cl)c(F)c1 nan
714273 22851 12 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 244 2 0 6 0.9 N#Cc1nc(N2CCCC2)nc(N2CCCC2)n1 nan
CHEMBL1328481 22851 12 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 244 2 0 6 0.9 N#Cc1nc(N2CCCC2)nc(N2CCCC2)n1 nan
2811299 44820 5 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 315 3 1 5 2.4 Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1522108 44820 5 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 315 3 1 5 2.4 Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc2c(c1)OCO2 nan
1126136 55845 13 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 0 5 3.3 CSc1ccc(CN2CCN(C(=O)c3ccc([N+](=O)[O-])cc3)CC2)cc1 nan
CHEMBL1522672 55845 13 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 0 5 3.3 CSc1ccc(CN2CCN(C(=O)c3ccc([N+](=O)[O-])cc3)CC2)cc1 nan
CHEMBL1623172 55845 13 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 0 5 3.3 CSc1ccc(CN2CCN(C(=O)c3ccc([N+](=O)[O-])cc3)CC2)cc1 nan
660194 32200 17 None 6 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 319 8 1 7 1.6 C=CCNc1nc2c(c(=O)n(C)c(=O)n2C)n1CCCCCC nan
CHEMBL1409445 32200 17 None 6 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 319 8 1 7 1.6 C=CCNc1nc2c(c(=O)n(C)c(=O)n2C)n1CCCCCC nan
1599306 14155 7 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 220 8 1 2 3.7 CCCCCCCCCn1ccc(=N)cc1 nan
CHEMBL1198353 14155 7 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 220 8 1 2 3.7 CCCCCCCCCn1ccc(=N)cc1 nan
CHEMBL601933 14155 7 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 220 8 1 2 3.7 CCCCCCCCCn1ccc(=N)cc1 nan
646580 30377 5 None 6 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 382 5 3 7 1.9 CC(C)(C)NC(=O)COC(=O)c1snc(C(=O)NC2CCCCC2)c1N nan
CHEMBL1392033 30377 5 None 6 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 382 5 3 7 1.9 CC(C)(C)NC(=O)COC(=O)c1snc(C(=O)NC2CCCCC2)c1N nan
3237192 47499 3 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.2 Cc1oc(-c2ccc(Cl)cc2)nc1CN1CCCC(C(=O)NCc2cccnc2)C1 nan
CHEMBL1545631 47499 3 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.2 Cc1oc(-c2ccc(Cl)cc2)nc1CN1CCCC(C(=O)NCc2cccnc2)C1 nan
69765 85128 74 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 251 1 1 3 3.9 CC(C)(C)c1cc([N+](=O)[O-])cc(C(C)(C)C)c1O nan
CHEMBL224869 85128 74 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 251 1 1 3 3.9 CC(C)(C)c1cc([N+](=O)[O-])cc(C(C)(C)C)c1O nan
20968908 19615 5 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 528 11 1 6 3.9 Cc1oc(-c2ccc(Cl)cc2)nc1C[S+]([O-])CC(=O)NCCCN1CCN(Cc2ccccc2)CC1 nan
CHEMBL1300302 19615 5 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 528 11 1 6 3.9 Cc1oc(-c2ccc(Cl)cc2)nc1C[S+]([O-])CC(=O)NCCCN1CCN(Cc2ccccc2)CC1 nan
71821 45301 40 None - 1 Human 6.7 pIC50 = 6.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 256 2 0 2 4.0 Cc1nc2ccccc2n1Cc1ccc(Cl)cc1 nan
CHEMBL152649 45301 40 None - 1 Human 6.7 pIC50 = 6.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 256 2 0 2 4.0 Cc1nc2ccccc2n1Cc1ccc(Cl)cc1 nan
936105 46157 12 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 332 4 1 4 2.4 O=S(=O)(NCc1ccncc1)c1ccc(Br)s1 nan
CHEMBL1534042 46157 12 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 332 4 1 4 2.4 O=S(=O)(NCc1ccncc1)c1ccc(Br)s1 nan
3236301 37519 11 None 4 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 1 1 7 -0.3 CCc1nc2c([nH]1)c1no[n+]([O-])c1c1no[n+]([O-])c21 nan
CHEMBL1455957 37519 11 None 4 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 1 1 7 -0.3 CCc1nc2c([nH]1)c1no[n+]([O-])c1c1no[n+]([O-])c21 nan
2100274 24721 2 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 418 3 0 8 2.0 O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(c2ncnc3sccc23)CC1 nan
CHEMBL1344025 24721 2 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 418 3 0 8 2.0 O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(c2ncnc3sccc23)CC1 nan
2795678 51724 5 None 4 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 434 2 1 4 5.7 Cc1cccc(Cl)c1NC(=O)N1CCCN(c2nc3ccc(Cl)cc3s2)CC1 nan
CHEMBL1584471 51724 5 None 4 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 434 2 1 4 5.7 Cc1cccc(Cl)c1NC(=O)N1CCCN(c2nc3ccc(Cl)cc3s2)CC1 nan
2738599 45050 5 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 6 1 4 3.1 CN1CCN(c2ccc(CNS(=O)(=O)Cc3cccc(C(F)(F)F)c3)cc2)CC1 nan
CHEMBL1524322 45050 5 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 6 1 4 3.1 CN1CCN(c2ccc(CNS(=O)(=O)Cc3cccc(C(F)(F)F)c3)cc2)CC1 nan
3323365 40015 15 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 3 1 4 4.4 Cc1nn(C)c(Cl)c1NC(=O)OCc1ccc(Cl)cc1Cl nan
CHEMBL1478769 40015 15 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 3 1 4 4.4 Cc1nn(C)c(Cl)c1NC(=O)OCc1ccc(Cl)cc1Cl nan
3237836 44974 8 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.1 N#CCSc1nc(N)c(C#N)c(C2CCCCC2)c1C#N nan
CHEMBL1523520 44974 8 None - 1 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.1 N#CCSc1nc(N)c(C#N)c(C2CCCCC2)c1C#N nan
663916 38225 8 None 3 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 259 4 1 3 3.4 CCCCOc1[nH]cnc2c3cc(F)ccc3nc1-2 nan
CHEMBL1462076 38225 8 None 3 2 Human 5.7 pIC50 = 5.7 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 259 4 1 3 3.4 CCCCOc1[nH]cnc2c3cc(F)ccc3nc1-2 nan
1653621 22479 21 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 298 6 1 3 4.6 CCCOc1ccc(CSc2nc3ccccc3[nH]2)cc1 nan
CHEMBL1325226 22479 21 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 298 6 1 3 4.6 CCCOc1ccc(CSc2nc3ccccc3[nH]2)cc1 nan
4352110 26582 7 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 3 4 9 2.3 COc1ccc(C2CC(=O)Nc3sc(=N)c4c(N)c(C#N)c(N)nc4c32)cc1OC nan
CHEMBL1361038 26582 7 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 3 4 9 2.3 COc1ccc(C2CC(=O)Nc3sc(=N)c4c(N)c(C#N)c(N)nc4c32)cc1OC nan
24793944 41757 2 None - 1 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 357 3 1 5 2.7 Cn1nccc1C(=O)NC1CCCc2c1cnn2-c1ccc(F)cc1F nan
CHEMBL1492752 41757 2 None - 1 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 357 3 1 5 2.7 Cn1nccc1C(=O)NC1CCCc2c1cnn2-c1ccc(F)cc1F nan
616573 4598 26 None 2 2 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
CHEMBL102726 4598 26 None 2 2 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
CHEMBL1444764 4598 26 None 2 2 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
16196224 55484 2 None 51 2 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
2320816 55484 2 None 51 2 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
5668087 55484 2 None 51 2 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
CHEMBL1422429 55484 2 None 51 2 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
CHEMBL1620064 55484 2 None 51 2 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
3111187 47547 41 None - 1 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 248 2 2 5 1.0 CC1CC(=O)NN=C1c1ccc(N)c([N+](=O)[O-])c1 nan
CHEMBL1546066 47547 41 None - 1 Human 6.6 pIC50 = 6.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 248 2 2 5 1.0 CC1CC(=O)NN=C1c1ccc(N)c([N+](=O)[O-])c1 nan
1095440 44206 17 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 359 6 2 3 3.7 CC(=O)c1cn(CC(=O)NCCc2c[nH]c3ccccc23)c2ccccc12 nan
CHEMBL1516566 44206 17 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 359 6 2 3 3.7 CC(=O)c1cn(CC(=O)NCCc2c[nH]c3ccccc23)c2ccccc12 nan
20919845 31340 6 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 475 8 1 8 2.9 COc1ccc(OC)c(CCNC(=O)Cn2nc(C)c3c(C)n(-c4ccc(C)cc4)nc3c2=O)c1 nan
CHEMBL1401965 31340 6 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 475 8 1 8 2.9 COc1ccc(OC)c(CCNC(=O)Cn2nc(C)c3c(C)n(-c4ccc(C)cc4)nc3c2=O)c1 nan
16190638 53663 3 None 9 2 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 5 1 4 4.0 CCC1C(=O)NCCN1Cc1nc(-c2ccc(-c3ccccc3)cc2)oc1C nan
CHEMBL1603032 53663 3 None 9 2 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 5 1 4 4.0 CCC1C(=O)NCCN1Cc1nc(-c2ccc(-c3ccccc3)cc2)oc1C nan
23723905 59636 6 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 391 6 1 5 3.9 CC(C)(C)CN1CCN(Cc2nc(-c3ccc(F)cc3)cs2)CC1CCO nan
CHEMBL1720771 59636 6 None - 1 Human 5.6 pIC50 = 5.6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 391 6 1 5 3.9 CC(C)(C)CN1CCN(Cc2nc(-c3ccc(F)cc3)cs2)CC1CCO nan
44246639 59552 0 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 484 7 0 7 3.7 Cc1cc(C)c(CN2CCN(C(=O)Cn3cnc4c(OCc5ccccc5)ncnc43)CC2)c(C)c1 nan
CHEMBL1717082 59552 0 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 484 7 0 7 3.7 Cc1cc(C)c(CN2CCN(C(=O)Cn3cnc4c(OCc5ccccc5)ncnc43)CC2)c(C)c1 nan
2534514 59295 5 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 357 6 2 4 2.7 O=C(COC(=O)c1[nH]nc2ccccc12)NCCc1ccc(Cl)cc1 nan
CHEMBL1705059 59295 5 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 357 6 2 4 2.7 O=C(COC(=O)c1[nH]nc2ccccc12)NCCc1ccc(Cl)cc1 nan
135399075 19817 7 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 420 7 2 8 3.7 Cc1cc(C(=O)CSc2nc(N)cc(O)n2)c(C)n1-c1ccc(OC(F)F)cc1 nan
CHEMBL1301887 19817 7 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 420 7 2 8 3.7 Cc1cc(C(=O)CSc2nc(N)cc(O)n2)c(C)n1-c1ccc(OC(F)F)cc1 nan
1163593 53294 10 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 481 8 2 6 3.6 COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(CN4CCOCC4)cc3)cc2)cc1 nan
CHEMBL1599462 53294 10 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 481 8 2 6 3.6 COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(CN4CCOCC4)cc3)cc2)cc1 nan
2548270 49790 9 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 362 5 2 6 2.6 Cc1sc2ncnc(NCCc3ccc(S(N)(=O)=O)cc3)c2c1C nan
CHEMBL1567331 49790 9 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 362 5 2 6 2.6 Cc1sc2ncnc(NCCc3ccc(S(N)(=O)=O)cc3)c2c1C nan
108144 207682 74 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 423 5 2 6 3.2 NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N nan
CHEMBL95431 207682 74 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 423 5 2 6 3.2 NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N nan
951643 47924 9 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 274 3 0 3 3.8 CC(=O)c1cn(Cc2ccccc2C#N)c2ccccc12 nan
CHEMBL1549500 47924 9 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 274 3 0 3 3.8 CC(=O)c1cn(Cc2ccccc2C#N)c2ccccc12 nan
6902566 108181 3 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 3 2 2 3.8 FC(F)(F)c1cccc(/C=N/NC(=S)NC2CCCCC2)c1 nan
CHEMBL3196315 108181 3 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 3 2 2 3.8 FC(F)(F)c1cccc(/C=N/NC(=S)NC2CCCCC2)c1 nan
646118 31949 5 None 5 2 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 311 6 1 6 2.7 CCc1c(C)nc2ncnn2c1NCCc1ccc(OC)cc1 nan
CHEMBL1407572 31949 5 None 5 2 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 311 6 1 6 2.7 CCc1c(C)nc2ncnn2c1NCCc1ccc(OC)cc1 nan
1321677 34114 9 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 432 7 1 4 5.4 Cc1cc(CSc2ccccc2)ccc1NC(=O)c1ccc(CN2CCOCC2)cc1 nan
CHEMBL1425552 34114 9 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 432 7 1 4 5.4 Cc1cc(CSc2ccccc2)ccc1NC(=O)c1ccc(CN2CCOCC2)cc1 nan
2139165 53812 14 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 236 2 0 2 3.7 Cc1ccccc1Cn1c(C)nc2ccccc21 nan
CHEMBL1604200 53812 14 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 236 2 0 2 3.7 Cc1ccccc1Cn1c(C)nc2ccccc21 nan
135549777 109157 5 None 7 2 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 471 7 1 9 4.1 C/C(=N\OCc1nc2ccccc2c(=O)n1/N=C/c1cc(C)cc([N+](=O)[O-])c1O)c1ccccc1 nan
CHEMBL3214310 109157 5 None 7 2 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 471 7 1 9 4.1 C/C(=N\OCc1nc2ccccc2c(=O)n1/N=C/c1cc(C)cc([N+](=O)[O-])c1O)c1ccccc1 nan
49778246 67616 0 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 484 7 2 8 4.2 OC[C@@H]1CN(Cc2ccc(-c3ccccc3)cc2)C[C@H](n2cnc3c(NC4CCCC4)ncnc32)O1 nan
CHEMBL1903414 67616 0 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 484 7 2 8 4.2 OC[C@@H]1CN(Cc2ccc(-c3ccccc3)cc2)C[C@H](n2cnc3c(NC4CCCC4)ncnc32)O1 nan
4143977 59528 5 None 2 2 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 461 7 1 7 4.6 COCC(C)n1c(-c2ccc3c(c2)NC(=O)CO3)cs/c1=N\c1ccc(OC(F)F)cc1 nan
CHEMBL1716038 59528 5 None 2 2 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 461 7 1 7 4.6 COCC(C)n1c(-c2ccc3c(c2)NC(=O)CO3)cs/c1=N\c1ccc(OC(F)F)cc1 nan
16397324 42582 6 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 435 14 2 4 4.8 CCCCC[C@H](O)/C=C/[C@H]1CCC(=O)[C@@H]1CCCCCCC(=O)N1CCCCC1CO nan
CHEMBL1500445 42582 6 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 435 14 2 4 4.8 CCCCC[C@H](O)/C=C/[C@H]1CCC(=O)[C@@H]1CCCCCCC(=O)N1CCCCC1CO nan
693933 47730 14 None 3 3 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 327 3 1 3 3.9 Nc1cc(-c2ccc(Br)cc2)nn1Cc1ccccc1 nan
CHEMBL1547757 47730 14 None 3 3 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 327 3 1 3 3.9 Nc1cc(-c2ccc(Br)cc2)nn1Cc1ccccc1 nan
24819426 51618 3 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 435 7 1 5 4.9 COc1ccc(CN2CCC(C(=O)Nc3ccc(Oc4ccccc4)nc3)CC2)cc1F nan
CHEMBL1583610 51618 3 None - 1 Human 5.5 pIC50 = 5.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 435 7 1 5 4.9 COc1ccc(CN2CCC(C(=O)Nc3ccc(Oc4ccccc4)nc3)CC2)cc1F nan
46943517 72236 0 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 431 7 1 5 5.4 COc1ccc(-c2coc3c(C(=O)NCc4ccc(OC)c(OC)c4)cccc23)c(C)c1 nan
CHEMBL1981589 72236 0 None - 1 Human 6.5 pIC50 = 6.5 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 431 7 1 5 5.4 COc1ccc(-c2coc3c(C(=O)NCc4ccc(OC)c(OC)c4)cccc23)c(C)c1 nan
44601539 59440 0 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 483 7 1 7 3.7 Cc1cc(C)c(CN2CCN(C(=O)Cn3cnc4c(NCc5ccccc5)ncnc43)CC2)c(C)c1 nan
CHEMBL1711360 59440 0 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 483 7 1 7 3.7 Cc1cc(C)c(CN2CCN(C(=O)Cn3cnc4c(NCc5ccccc5)ncnc43)CC2)c(C)c1 nan
3695590 50040 13 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 292 5 3 6 0.9 CC1CC(=O)NN=C1c1ccc(NCCO)c([N+](=O)[O-])c1 nan
CHEMBL1569489 50040 13 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 292 5 3 6 0.9 CC1CC(=O)NN=C1c1ccc(NCCO)c([N+](=O)[O-])c1 nan
417935 55130 2 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 275 1 0 1 3.8 CC1(C)CC(N2CCCCC2)=CC(=[N+]2CCCCC2)C1 nan
CHEMBL1342790 55130 2 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 275 1 0 1 3.8 CC1(C)CC(N2CCCCC2)=CC(=[N+]2CCCCC2)C1 nan
CHEMBL1617098 55130 2 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 275 1 0 1 3.8 CC1(C)CC(N2CCCCC2)=CC(=[N+]2CCCCC2)C1 nan
2128618 23976 6 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 353 7 0 6 3.3 COCCn1c(C)cc(C(=O)COc2nc3ccccc3nc2C)c1C nan
CHEMBL1337567 23976 6 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 353 7 0 6 3.3 COCCn1c(C)cc(C(=O)COc2nc3ccccc3nc2C)c1C nan
135431504 44614 10 None 3 2 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 308 2 2 7 3.3 Nc1nn2c(O)c3c(nc2c1N=Nc1ccccc1)CCCC3 nan
CHEMBL1520388 44614 10 None 3 2 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 308 2 2 7 3.3 Nc1nn2c(O)c3c(nc2c1N=Nc1ccccc1)CCCC3 nan
2100093 33901 13 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 315 6 1 6 3.4 COc1ccc(CCNc2ncnc3sccc23)cc1OC nan
CHEMBL1423660 33901 13 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 315 6 1 6 3.4 COc1ccc(CCNc2ncnc3sccc23)cc1OC nan
2326905 19647 5 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 310 4 1 3 4.8 CNc1ccccc1C(C)(C)c1cc(-c2ccc(F)cc2)no1 nan
CHEMBL1300536 19647 5 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 310 4 1 3 4.8 CNc1ccccc1C(C)(C)c1cc(-c2ccc(F)cc2)no1 nan
663797 31148 8 None 104 2 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.4 COc1cccc2[nH]c3c(N4CCC(C)CC4)ncnc3c12 nan
CHEMBL1400272 31148 8 None 104 2 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.4 COc1cccc2[nH]c3c(N4CCC(C)CC4)ncnc3c12 nan
4323685 59650 8 None - 1 Human 7.4 pIC50 = 7.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 3 0 6 3.8 COc1cc2c(cc1OC)C1C(=O)c3ccc4c(c3OC1CO2)CC(C(C)C)O4 nan
CHEMBL1721226 59650 8 None - 1 Human 7.4 pIC50 = 7.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 3 0 6 3.8 COc1cc2c(cc1OC)C1C(=O)c3ccc4c(c3OC1CO2)CC(C(C)C)O4 nan
944164 34471 8 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 292 4 2 3 4.4 C1=C(CCNc2[nH]cnc3c4ccccc4nc2-3)CCCC1 nan
CHEMBL1428566 34471 8 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 292 4 2 3 4.4 C1=C(CCNc2[nH]cnc3c4ccccc4nc2-3)CCCC1 nan
3548924 27929 7 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 358 5 1 7 2.6 CCOC(=O)Cc1csc(NC(=O)c2cc(=O)c3ccccc3o2)n1 nan
CHEMBL1371941 27929 7 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 358 5 1 7 2.6 CCOC(=O)Cc1csc(NC(=O)c2cc(=O)c3ccccc3o2)n1 nan
1218 3616 30 None -2691 4 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 289 1 3 3 3.0 Oc1c(O)cc2c(c1Cl)CCNCC2c1ccccc1 nan
938 3616 30 None -2691 4 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 289 1 3 3 3.0 Oc1c(O)cc2c(c1Cl)CCNCC2c1ccccc1 nan
CHEMBL353335 3616 30 None -2691 4 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 289 1 3 3 3.0 Oc1c(O)cc2c(c1Cl)CCNCC2c1ccccc1 nan
3380750 109162 12 None 3 2 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 521 5 1 6 6.9 CO/C(O)=C1\C(C)=NC2=C(C(=O)CCC2)C1c1cn(Cc2ccc(Cl)cc2Cl)nc1-c1ccccc1 nan
CHEMBL3214406 109162 12 None 3 2 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 521 5 1 6 6.9 CO/C(O)=C1\C(C)=NC2=C(C(=O)CCC2)C1c1cn(Cc2ccc(Cl)cc2Cl)nc1-c1ccccc1 nan
53382850 80214 0 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 353 4 2 3 4.4 Nc1nc2ccccc2cc1C(=O)NCc1ccc(-c2ccccc2)cc1 nan
CHEMBL2136916 80214 0 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 353 4 2 3 4.4 Nc1nc2ccccc2cc1C(=O)NCc1ccc(-c2ccccc2)cc1 nan
51360281 80075 0 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 453 4 3 10 0.1 CN(Cc1ccc2c(c1)CCCN2C)C(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O nan
CHEMBL2130641 80075 0 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 453 4 3 10 0.1 CN(Cc1ccc2c(c1)CCCN2C)C(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O nan
2534340 34010 9 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 332 6 1 4 3.3 O=C(COc1ccc(C(=O)c2ccccc2)cc1)Nc1cccnc1 nan
CHEMBL1424583 34010 9 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 332 6 1 4 3.3 O=C(COc1ccc(C(=O)c2ccccc2)cc1)Nc1cccnc1 nan
663629 19616 7 None 100 2 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.4 COc1cccc2[nH]c3c(N4CCCC(C)C4)ncnc3c12 nan
CHEMBL1300327 19616 7 None 100 2 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.4 COc1cccc2[nH]c3c(N4CCCC(C)C4)ncnc3c12 nan
49795269 88583 0 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 412 6 3 7 3.4 O=C(Nc1ccc(Oc2ccccc2)cc1)c1csc([C@H]2C[C@H](O)[C@@H](CO)O2)n1 nan
CHEMBL2355112 88583 0 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 412 6 3 7 3.4 O=C(Nc1ccc(Oc2ccccc2)cc1)c1csc([C@H]2C[C@H](O)[C@@H](CO)O2)n1 nan
4525145 55638 5 None 16 3 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
6140197 55638 5 None 16 3 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
73945770 55638 5 None 16 3 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
CHEMBL1462215 55638 5 None 16 3 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
CHEMBL1621471 55638 5 None 16 3 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
24792082 54553 1 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 4 2 4 2.9 CC(C)(C)c1ccc(-n2ncc3c2CCCC3NC(=O)C2(C(N)=O)CC2)cc1 nan
CHEMBL1610300 54553 1 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 4 2 4 2.9 CC(C)(C)c1ccc(-n2ncc3c2CCCC3NC(=O)C2(C(N)=O)CC2)cc1 nan
16306739 35334 5 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 464 8 0 8 2.2 COc1ccc(CN(C)c2ccc(S(=O)(=O)N3CCN(C)CC3)cc2[N+](=O)[O-])cc1OC nan
CHEMBL1437030 35334 5 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 464 8 0 8 2.2 COc1ccc(CN(C)c2ccc(S(=O)(=O)N3CCN(C)CC3)cc2[N+](=O)[O-])cc1OC nan
4143977 59528 5 None 2 2 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 461 7 1 7 4.6 COCC(C)n1c(-c2ccc3c(c2)NC(=O)CO3)cs/c1=N\c1ccc(OC(F)F)cc1 nan
CHEMBL1716038 59528 5 None 2 2 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 461 7 1 7 4.6 COCC(C)n1c(-c2ccc3c(c2)NC(=O)CO3)cs/c1=N\c1ccc(OC(F)F)cc1 nan
2229408 56111 16 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 6 1 6 3.7 COc1ccc(CCNc2ncnc3sc(C)cc23)cc1OC nan
CHEMBL1603001 56111 16 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 6 1 6 3.7 COc1ccc(CCNc2ncnc3sc(C)cc23)cc1OC nan
CHEMBL1625429 56111 16 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 6 1 6 3.7 COc1ccc(CCNc2ncnc3sc(C)cc23)cc1OC nan
24790916 31053 6 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 433 8 1 8 3.1 CCOC(=O)CCN(c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(O)nn2)s1 nan
CHEMBL1399389 31053 6 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 433 8 1 8 3.1 CCOC(=O)CCN(c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(O)nn2)s1 nan
24819837 27342 5 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 314 3 1 2 4.2 O=C(Cc1ccc(Cl)cc1Cl)Nc1ccncc1Cl nan
CHEMBL1367597 27342 5 None - 1 Human 5.4 pIC50 = 5.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 314 3 1 2 4.2 O=C(Cc1ccc(Cl)cc1Cl)Nc1ccncc1Cl nan
24792017 31685 2 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 423 7 0 7 3.8 CCOC(=O)CC1CCCCN1C(=O)c1cc(COc2cccc3cnccc23)on1 nan
CHEMBL1405288 31685 2 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 423 7 0 7 3.8 CCOC(=O)CC1CCCCN1C(=O)c1cc(COc2cccc3cnccc23)on1 nan
24980848 41871 5 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 524 10 2 7 2.1 CCN(CC)S(=O)(=O)c1cc(NC(=O)CNc2cccc(S(=O)(=O)N3CCOCC3)c2)ccc1C nan
CHEMBL1493864 41871 5 None - 1 Human 6.4 pIC50 = 6.4 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 524 10 2 7 2.1 CCN(CC)S(=O)(=O)c1cc(NC(=O)CNc2cccc(S(=O)(=O)N3CCOCC3)c2)ccc1C nan
2552706 32653 4 None 20 2 Human 6.3 pIC50 = 6.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 487 6 0 9 5.6 O=c1cc(CSc2nnc(-c3cccs3)n2Cc2ccccc2)nc2sc3ccccc3n12 nan
CHEMBL1413056 32653 4 None 20 2 Human 6.3 pIC50 = 6.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 487 6 0 9 5.6 O=c1cc(CSc2nnc(-c3cccs3)n2Cc2ccccc2)nc2sc3ccccc3n12 nan
386315 67318 1 None - 1 Human 6.3 pIC50 = 6.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 583 7 1 14 1.8 CC(=O)OCC1OC(n2c(S)c(C#N)c(-c3ccccc3)c(C#N)c2=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O nan
CHEMBL1884207 67318 1 None - 1 Human 6.3 pIC50 = 6.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 583 7 1 14 1.8 CC(=O)OCC1OC(n2c(S)c(C#N)c(-c3ccccc3)c(C#N)c2=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O nan
2311088 55650 4 None 1 3 Human 5.3 pIC50 = 5.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 387 3 0 2 5.2 COc1ccc(-[n+]2c(-c3ccc(Cl)cc3)cn3c2CCc2ccccc2-3)cc1 nan
CHEMBL1457690 55650 4 None 1 3 Human 5.3 pIC50 = 5.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 387 3 0 2 5.2 COc1ccc(-[n+]2c(-c3ccc(Cl)cc3)cn3c2CCc2ccccc2-3)cc1 nan
CHEMBL1621585 55650 4 None 1 3 Human 5.3 pIC50 = 5.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 387 3 0 2 5.2 COc1ccc(-[n+]2c(-c3ccc(Cl)cc3)cn3c2CCc2ccccc2-3)cc1 nan
1245647 36345 14 None - 1 Human 6.3 pIC50 = 6.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 NC(=O)c1c(-c2ccc(Cl)cc2Cl)csc1NC(=O)Cc1ccccc1 nan
CHEMBL1446412 36345 14 None - 1 Human 6.3 pIC50 = 6.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 NC(=O)c1c(-c2ccc(Cl)cc2Cl)csc1NC(=O)Cc1ccccc1 nan
1400355 21849 9 None - 1 Human 5.3 pIC50 = 5.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 377 7 3 4 2.8 CCC(NCCC(c1ccccc1)c1ccccc1)=C1C(=O)NC(=O)NC1=O nan
CHEMBL1319737 21849 9 None - 1 Human 5.3 pIC50 = 5.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 377 7 3 4 2.8 CCC(NCCC(c1ccccc1)c1ccccc1)=C1C(=O)NC(=O)NC1=O nan
135411696 41910 10 None - 1 Human 6.3 pIC50 = 6.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 389 4 1 6 4.3 COc1c(/C=C2\SC(Nc3ccccc3Cl)=NC2=O)cccc1[N+](=O)[O-] nan
CHEMBL1494282 41910 10 None - 1 Human 6.3 pIC50 = 6.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 389 4 1 6 4.3 COc1c(/C=C2\SC(Nc3ccccc3Cl)=NC2=O)cccc1[N+](=O)[O-] nan
20231 33115 33 None - 1 Human 5.3 pIC50 = 5.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 210 1 1 3 2.6 Cc1nc(O)c(C#N)cc1-c1ccccc1 nan
CHEMBL1417067 33115 33 None - 1 Human 5.3 pIC50 = 5.3 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 210 1 1 3 2.6 Cc1nc(O)c(C#N)cc1-c1ccccc1 nan
309279 67206 1 None - 1 Human 5.2 pIC50 = 5.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 456 4 0 7 5.1 COc1ccc(C2=CC(c3ccc4c(c3)OCO4)c3c(c4ccccc4oc3=O)O2)cc1OC nan
CHEMBL1878306 67206 1 None - 1 Human 5.2 pIC50 = 5.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 456 4 0 7 5.1 COc1ccc(C2=CC(c3ccc4c(c3)OCO4)c3c(c4ccccc4oc3=O)O2)cc1OC nan
2240759 41435 14 None - 1 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 326 6 1 4 2.6 CCOc1cc(S(=O)(=O)NCc2ccncc2)ccc1Cl nan
CHEMBL1490503 41435 14 None - 1 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 326 6 1 4 2.6 CCOc1cc(S(=O)(=O)NCc2ccncc2)ccc1Cl nan
2464572 22047 6 None - 1 Human 5.2 pIC50 = 5.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 460 10 0 7 4.5 COCCn1c(SCCCC(=O)c2ccc(Br)cc2)nnc1-c1ccncc1 nan
CHEMBL1321513 22047 6 None - 1 Human 5.2 pIC50 = 5.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 460 10 0 7 4.5 COCCn1c(SCCCC(=O)c2ccc(Br)cc2)nnc1-c1ccncc1 nan
91754 85250 63 None - 1 Human 8.2 pIC50 = 8.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 364 3 0 4 5.2 CC(C)(C)c1ccc(CSc2cnn(C(C)(C)C)c(=O)c2Cl)cc1 nan
CHEMBL225963 85250 63 None - 1 Human 8.2 pIC50 = 8.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 364 3 0 4 5.2 CC(C)(C)c1ccc(CSc2cnn(C(C)(C)C)c(=O)c2Cl)cc1 nan
187 255 39 None -22 8 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
294 255 39 None -22 8 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
65 255 39 None -22 8 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
8593 255 39 None -22 8 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
CHEMBL667 255 39 None -22 8 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
DB03128 255 39 None -22 8 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
261711 59560 3 None - 1 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 4 2 4 2.7 Cc1ccc(CCNc2ncnc(Cl)c2N)cc1 nan
CHEMBL1717339 59560 3 None - 1 Human 6.2 pIC50 = 6.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 4 2 4 2.7 Cc1ccc(CCNc2ncnc(Cl)c2N)cc1 nan
659242 29839 14 None - 1 Human 5.2 pIC50 = 5.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 300 2 1 5 3.4 CSc1nc(N)c(C#N)c(-c2ccccc2Cl)c1C#N nan
CHEMBL1387556 29839 14 None - 1 Human 5.2 pIC50 = 5.2 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 300 2 1 5 3.4 CSc1nc(N)c(C#N)c(-c2ccccc2Cl)c1C#N nan
1726 2497 13 None -933 8 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
1993 2497 13 None -933 8 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
7438 2497 13 None -933 8 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
CHEMBL978 2497 13 None -933 8 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
DB06709 2497 13 None -933 8 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
2421595 28537 6 None 26 2 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 417 7 0 7 3.9 COc1ccc(-n2c(C)cc(C(=O)COC(=O)Cn3cnc4ccccc43)c2C)cc1 nan
CHEMBL1376266 28537 6 None 26 2 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 417 7 0 7 3.9 COc1ccc(-n2c(C)cc(C(=O)COC(=O)Cn3cnc4ccccc43)c2C)cc1 nan
4295603 29001 6 None - 1 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 561 6 1 6 3.5 CC1(C)CC2CC(C)(CN2S(=O)(=O)c2ccc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)cc2)C1 nan
CHEMBL1380444 29001 6 None - 1 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 561 6 1 6 3.5 CC1(C)CC2CC(C)(CN2S(=O)(=O)c2ccc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)cc2)C1 nan
4573346 39990 13 None - 1 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 281 3 2 4 2.6 Cn1c(C(=O)NN)cc2cc(Oc3ccccc3)ccc21 nan
CHEMBL1478533 39990 13 None - 1 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 281 3 2 4 2.6 Cn1c(C(=O)NN)cc2cc(Oc3ccccc3)ccc21 nan
730925 36778 10 None - 1 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 278 3 1 4 3.7 N#Cc1cc(-c2ccccc2)oc1NC(=O)c1ccco1 nan
CHEMBL1449874 36778 10 None - 1 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 278 3 1 4 3.7 N#Cc1cc(-c2ccccc2)oc1NC(=O)c1ccco1 nan
659248 194372 10 None 1 3 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 258 5 1 2 3.5 CCCCCCn1c2c(c(=N)c3c1CCC3)CCC2 nan
CHEMBL528708 194372 10 None 1 3 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 258 5 1 2 3.5 CCCCCCn1c2c(c(=N)c3c1CCC3)CCC2 nan
CHEMBL530291 194372 10 None 1 3 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 258 5 1 2 3.5 CCCCCCn1c2c(c(=N)c3c1CCC3)CCC2 nan
53299527 80194 0 None - 1 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 400 3 0 3 5.9 Cc1cc(Br)cn2c(Cc3cccc(Cl)c3)c(-c3ccco3)nc12 nan
CHEMBL2136078 80194 0 None - 1 Human 5.1 pIC50 = 5.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 400 3 0 3 5.9 Cc1cc(Br)cn2c(Cc3cccc(Cl)c3)c(-c3ccco3)nc12 nan
2967368 33814 12 None 72 2 Human 7.1 pIC50 = 7.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.3 O=C(CSc1nnnn1C1CC2CCC1C2)Nc1ccnc2ccccc12 nan
CHEMBL1423004 33814 12 None 72 2 Human 7.1 pIC50 = 7.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.3 O=C(CSc1nnnn1C1CC2CCC1C2)Nc1ccnc2ccccc12 nan
934786 41059 11 None - 1 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 324 4 1 5 3.4 Cc1cc(C)nc(SCC(=O)Nc2ccnc3ccccc23)n1 nan
CHEMBL1487720 41059 11 None - 1 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 324 4 1 5 3.4 Cc1cc(C)nc(SCC(=O)Nc2ccnc3ccccc23)n1 nan
24817872 32606 6 None - 1 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 363 4 1 5 3.5 CCn1cc(C(=O)NC2CCCc3c2cnn3-c2cccc(C)c2C)cn1 nan
CHEMBL1412747 32606 6 None - 1 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 363 4 1 5 3.5 CCn1cc(C(=O)NC2CCCc3c2cnn3-c2cccc(C)c2C)cn1 nan
649098 48654 6 None 2 2 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 7 0 8 3.5 COc1ccc(C(=O)CSc2nnc(Cn3cnc4ccccc43)o2)cc1 nan
CHEMBL1557584 48654 6 None 2 2 Human 6.1 pIC50 = 6.1 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 7 0 8 3.5 COc1ccc(C(=O)CSc2nnc(Cn3cnc4ccccc43)o2)cc1 nan
33572 205201 8 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 287 6 4 4 2.4 C[C@H](NCCc1ccc(O)cc1)[C@H](O)c1ccc(O)cc1 nan
CHEMBL1201160 205201 8 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 287 6 4 4 2.4 C[C@H](NCCc1ccc(O)cc1)[C@H](O)c1ccc(O)cc1 nan
CHEMBL785 205201 8 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 287 6 4 4 2.4 C[C@H](NCCc1ccc(O)cc1)[C@H](O)c1ccc(O)cc1 nan
4412278 47285 6 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 561 6 1 6 3.5 CC1(C)CC2CC(C)(CN2S(=O)(=O)c2ccc(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)cc2)C1 nan
CHEMBL1544054 47285 6 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 561 6 1 6 3.5 CC1(C)CC2CC(C)(CN2S(=O)(=O)c2ccc(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)cc2)C1 nan
1740950 32820 7 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 469 5 1 6 6.3 Cc1ccccc1-c1cc(C(=O)Nc2sc(C(=O)OC(C)C)c(C)c2C#N)c2ccccc2n1 nan
CHEMBL1414465 32820 7 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 469 5 1 6 6.3 Cc1ccccc1-c1cc(C(=O)Nc2sc(C(=O)OC(C)C)c(C)c2C#N)c2ccccc2n1 nan
2811624 46070 5 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 3 1 5 2.7 Cn1nc(C(C)(C)C)cc1C(=O)NCc1cc(F)cc2c1OCOC2 nan
CHEMBL1533321 46070 5 None - 1 Human 6.0 pIC50 = 6.0 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 3 1 5 2.7 Cn1nc(C(C)(C)C)cc1C(=O)NCc1cc(F)cc2c1OCOC2 nan
2204911 31023 9 None - 1 Human 6.0 pIC50 = 6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 360 7 1 3 3.7 CCCCc1ccc(NC(=O)c2ccc(N(C)S(C)(=O)=O)cc2)cc1 nan
CHEMBL1399125 31023 9 None - 1 Human 6.0 pIC50 = 6 Functional
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 360 7 1 3 3.7 CCCCc1ccc(NC(=O)c2ccc(N(C)S(C)(=O)=O)cc2)cc1 nan
11417 3648 0 None -3 2 Human 6.2 pEC50 = 6.2 Functional
Determined by measuring SRE-luc activity in HEK293-Gqi cells expressing hGALR3.Determined by measuring SRE-luc activity in HEK293-Gqi cells expressing hGALR3.
Guide to Pharmacology None None None None 24517231
16133243 1715 0 None -851 5 Rat 7.0 pIC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
3593 1715 0 None -851 5 Rat 7.0 pIC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
101927062 1716 22 None -1174 5 Human 7.1 pIC50 = 7.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
155817445 1716 22 None -1174 5 Human 7.1 pIC50 = 7.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
16133823 1716 22 None -1174 5 Human 7.1 pIC50 = 7.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
3592 1716 22 None -1174 5 Human 7.1 pIC50 = 7.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
44584852 1716 22 None -1174 5 Human 7.1 pIC50 = 7.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
6090 1716 22 None -1174 5 Human 7.1 pIC50 = 7.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
91898917 1716 22 None -1174 5 Human 7.1 pIC50 = 7.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
CHEMBL506553 1716 22 None -1174 5 Human 7.1 pIC50 = 7.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
155817484 1714 0 None -186 5 Human 7.9 pIC50 = 7.9 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
6117 1714 0 None -186 5 Human 7.9 pIC50 = 7.9 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
6129 1714 0 None -186 5 Human 7.9 pIC50 = 7.9 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
3594 1742 0 None 2 3 Human 8.0 pIC50 = 8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944009
3596 1740 0 None 29 2 Rat 8.8 pIC50 = 8.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
131863305 327 0 None -1 3 Rat 6.0 pIC50 > 6 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
155817486 327 0 None -1 3 Rat 6.0 pIC50 > 6 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
6123 327 0 None -1 3 Rat 6.0 pIC50 > 6 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399


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Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
Sel. page Similar-
ity		 Common
name		 GPCRdb
ID		 #Vendors

 Reference
ligand		 Fold
selectivity		 # Tested
GPCRs		 Species

 p-value
(-log)		 Activity
Type		 Activity
Relation		 Activity
Value		 Assay
Type		 Assay
Description		 Source

 Mol
weight		 Rot
Bonds		 H don

 H acc

 LogP

 Smiles

 DOI
CHEMBL503473 214167 14 None -478 3 Human 7.8 pKd = 7.8 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O 10.1021/jm801088x
16132180 1724 21 None -208 8 Human 6.5 pKd = 6.5 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
16133822 1724 21 None -208 8 Human 6.5 pKd = 6.5 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
6087 1724 21 None -208 8 Human 6.5 pKd = 6.5 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
CHEMBL499980 1724 21 None -208 8 Human 6.5 pKd = 6.5 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
CHEMBL526003 215669 29 None -416 3 Human 7.4 pKd = 7.4 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(N)=O 10.1021/jm801088x
155817464 1499 0 None -173 4 Human 7.2 pKd = 7.2 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
3866 1499 0 None -173 4 Human 7.2 pKd = 7.2 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
44587986 1499 0 None -173 4 Human 7.2 pKd = 7.2 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
91934870 1499 0 None -173 4 Human 7.2 pKd = 7.2 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
CHEMBL499179 1499 0 None -173 4 Human 7.2 pKd = 7.2 Binding
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
44414120 79855 0 None - 1 Human 6.0 pKi = 6 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1ccccc1N1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 10.1016/j.bmcl.2006.05.025
CHEMBL212224 79855 0 None - 1 Human 6.0 pKi = 6 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1ccccc1N1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 10.1016/j.bmcl.2006.05.025
11677898 139256 0 None - 1 Human 7.8 pKi = 7.8 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)CC(O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL378991 139256 0 None - 1 Human 7.8 pKi = 7.8 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)CC(O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
3561805 79984 15 None - 1 Human 6.8 pKi = 6.8 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 330 3 0 2 4.6 C=CCN1C(=O)/C(=N/c2ccc(Cl)c(Cl)c2)c2ccccc21 10.1021/jm060001n
CHEMBL212729 79984 15 None - 1 Human 6.8 pKi = 6.8 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 330 3 0 2 4.6 C=CCN1C(=O)/C(=N/c2ccc(Cl)c(Cl)c2)c2ccccc21 10.1021/jm060001n
1471834 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1021/jm060001n
6126 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1021/jm060001n
CHEMBL210288 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1021/jm060001n
1471834 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1016/j.bmcl.2006.05.025
6126 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1016/j.bmcl.2006.05.025
CHEMBL210288 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1016/j.bmcl.2006.05.025
44414299 139225 0 None 19 2 Human 7.7 pKi = 7.7 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 495 9 0 4 6.6 CCN(CC)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL378825 139225 0 None 19 2 Human 7.7 pKi = 7.7 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 495 9 0 4 6.6 CCN(CC)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414138 79524 0 None - 1 Human 7.6 pKi = 7.6 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 453 6 0 4 5.4 CN(C)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL211398 79524 0 None - 1 Human 7.6 pKi = 7.6 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 453 6 0 4 5.4 CN(C)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414234 77953 0 None - 1 Human 7.6 pKi = 7.6 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)C[C@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL209642 77953 0 None - 1 Human 7.6 pKi = 7.6 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)C[C@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414075 138470 0 None - 1 Human 7.5 pKi = 7.5 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 467 7 0 4 5.8 CN(C)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL377468 138470 0 None - 1 Human 7.5 pKi = 7.5 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 467 7 0 4 5.8 CN(C)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414225 79667 0 None - 1 Human 6.5 pKi = 6.5 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)C[C@@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL211522 79667 0 None - 1 Human 6.5 pKi = 6.5 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)C[C@@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
11540517 80261 0 None - 1 Human 7.5 pKi = 7.5 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 495 9 0 4 6.6 CCN(CC)CCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
CHEMBL213893 80261 0 None - 1 Human 7.5 pKi = 7.5 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 495 9 0 4 6.6 CCN(CC)CCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
44414235 141395 0 None - 1 Human 7.4 pKi = 7.4 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 467 7 0 4 6.2 CCN(CC)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL383941 141395 0 None - 1 Human 7.4 pKi = 7.4 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 467 7 0 4 6.2 CCN(CC)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
135559217 139236 3 None - 1 Human 6.4 pKi = 6.4 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 290 1 1 2 4.1 O=C1Nc2ccccc2/C1=N\c1cccc(Cl)c1Cl 10.1021/jm060001n
CHEMBL378877 139236 3 None - 1 Human 6.4 pKi = 6.4 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 290 1 1 2 4.1 O=C1Nc2ccccc2/C1=N\c1cccc(Cl)c1Cl 10.1021/jm060001n
44414058 77923 0 None - 1 Human 7.4 pKi = 7.4 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 509 10 0 4 7.0 CCN(CC)CCCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL209476 77923 0 None - 1 Human 7.4 pKi = 7.4 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 509 10 0 4 7.0 CCN(CC)CCCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414043 78374 0 None - 1 Human 7.3 pKi = 7.3 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 493 7 0 4 6.4 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCCN2CCCC2)c1 10.1016/j.bmcl.2006.05.025
CHEMBL211031 78374 0 None - 1 Human 7.3 pKi = 7.3 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 493 7 0 4 6.4 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCCN2CCCC2)c1 10.1016/j.bmcl.2006.05.025
11698643 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 10.1016/j.bmcl.2006.05.025
6125 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 10.1016/j.bmcl.2006.05.025
CHEMBL209497 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 10.1016/j.bmcl.2006.05.025
44412817 78458 0 None - 1 Human 7.3 pKi = 7.3 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 360 4 0 2 5.4 CCC(CC)N1C(=O)/C(=N/c2ccc(C(F)(F)F)cc2)c2ccccc21 10.1021/jm060001n
CHEMBL211169 78458 0 None - 1 Human 7.3 pKi = 7.3 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 360 4 0 2 5.4 CCC(CC)N1C(=O)/C(=N/c2ccc(C(F)(F)F)cc2)c2ccccc21 10.1021/jm060001n
135411930 77926 19 None - 1 Human 6.2 pKi = 6.2 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 290 1 1 2 3.8 O=C1Nc2ccccc2/C1=N\c1cccc(C(F)(F)F)c1 10.1021/jm060001n
CHEMBL209480 77926 19 None - 1 Human 6.2 pKi = 6.2 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 290 1 1 2 3.8 O=C1Nc2ccccc2/C1=N\c1cccc(C(F)(F)F)c1 10.1021/jm060001n
44414180 138404 0 None - 1 Human 7.2 pKi = 7.2 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 509 10 0 4 7.0 CCN(CC)CCCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
CHEMBL377328 138404 0 None - 1 Human 7.2 pKi = 7.2 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 509 10 0 4 7.0 CCN(CC)CCCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
11677377 79608 0 None - 1 Human 7.1 pKi = 7.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
CHEMBL211467 79608 0 None - 1 Human 7.1 pKi = 7.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
44414137 165974 0 None - 1 Human 6.1 pKi = 6.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccccc1OCCN1CCCC1 10.1016/j.bmcl.2006.05.025
CHEMBL425250 165974 0 None - 1 Human 6.1 pKi = 6.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccccc1OCCN1CCCC1 10.1016/j.bmcl.2006.05.025
11712935 77929 0 None - 1 Human 8.1 pKi = 8.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 493 6 0 4 6.4 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCN2CCCCC2)c1 10.1016/j.bmcl.2006.05.025
CHEMBL209498 77929 0 None - 1 Human 8.1 pKi = 8.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 493 6 0 4 6.4 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCN2CCCCC2)c1 10.1016/j.bmcl.2006.05.025
135411931 78003 38 None - 1 Human 6.1 pKi = 6.1 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 256 1 1 2 3.4 O=C1Nc2ccccc2/C1=N\c1ccc(Cl)cc1 10.1021/jm060001n
CHEMBL209737 78003 38 None - 1 Human 6.1 pKi = 6.1 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 256 1 1 2 3.4 O=C1Nc2ccccc2/C1=N\c1ccc(Cl)cc1 10.1021/jm060001n
44414042 77927 0 None - 1 Human 7.1 pKi = 7.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL209481 77927 0 None - 1 Human 7.1 pKi = 7.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
11544426 141984 0 None - 1 Human 7.1 pKi = 7.1 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 328 2 0 2 3.8 C#CCN1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 10.1021/jm060001n
CHEMBL387401 141984 0 None - 1 Human 7.1 pKi = 7.1 Binding
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 328 2 0 2 3.8 C#CCN1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 10.1021/jm060001n
11698159 78001 0 None - 1 Human 7.1 pKi = 7.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 453 6 0 4 5.4 CN(C)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
CHEMBL209730 78001 0 None - 1 Human 7.1 pKi = 7.1 Binding
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 453 6 0 4 5.4 CN(C)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
155817484 1714 0 None -22 6 Human 8.7 pKd = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817484 1714 0 None -22 6 Human 8.7 pKd = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6117 1714 0 None -22 6 Human 8.7 pKd = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6117 1714 0 None -22 6 Human 8.7 pKd = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6129 1714 0 None -22 6 Human 8.7 pKd = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6129 1714 0 None -22 6 Human 8.7 pKd = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817484 1714 0 None -10 6 Rat 9.1 pKd = 9.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817484 1714 0 None -10 6 Rat 9.1 pKd = 9.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6117 1714 0 None -10 6 Rat 9.1 pKd = 9.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6117 1714 0 None -10 6 Rat 9.1 pKd = 9.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6129 1714 0 None -10 6 Rat 9.1 pKd = 9.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6129 1714 0 None -10 6 Rat 9.1 pKd = 9.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6074 2442 0 None -301 3 Human 5.0 pKd > 5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23192661
None 216061 0 125I-GALANIN -37 5 Human 7.4 pKi = 7.4 Binding
NoneNone
PDSP KiDatabase 418 8 0 4 4.3 CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl None
6102 2439 0 None -30 3 Human 6.1 pKi = 6.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
6103 2440 0 None -18 3 Human 6.2 pKi = 6.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
6101 2438 0 None -75 3 Human 6.3 pKi = 6.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
16132180 1724 21 None -208 8 Human 6.5 pKi = 6.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16132180 1724 21 None -208 8 Human 6.5 pKi = 6.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
16133822 1724 21 None -208 8 Human 6.5 pKi = 6.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133822 1724 21 None -208 8 Human 6.5 pKi = 6.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6087 1724 21 None -208 8 Human 6.5 pKi = 6.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6087 1724 21 None -208 8 Human 6.5 pKi = 6.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
CHEMBL499980 1724 21 None -208 8 Human 6.5 pKi = 6.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
CHEMBL499980 1724 21 None -208 8 Human 6.5 pKi = 6.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817474 1728 0 None -16 5 Rat 6.6 pKi = 6.6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944007
5357 1728 0 None -16 5 Rat 6.6 pKi = 6.6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944007
6104 2441 0 None -45 3 Human 6.6 pKi = 6.6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
155817474 1728 0 None -12 5 Human 6.7 pKi = 6.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
5357 1728 0 None -12 5 Human 6.7 pKi = 6.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
3899 2447 0 None -933 8 Human 6.9 pKi = 6.9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3899 2447 0 None -933 8 Human 6.9 pKi = 6.9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6075 2108 0 None -5 3 Human 7.0 pKi = 7.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23600864
101927062 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
101927062 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817445 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817445 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
16133823 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133823 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
3592 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3592 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
44584852 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
44584852 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6090 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6090 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
91898917 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
91898917 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
CHEMBL506553 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
CHEMBL506553 1716 22 None -239 6 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
16132180 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
16132180 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16132180 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
16133822 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
16133822 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133822 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
6087 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6087 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6087 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
CHEMBL499980 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
CHEMBL499980 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
CHEMBL499980 1724 21 None -44 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
3899 2447 0 None -501 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
3899 2447 0 None -501 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3899 2447 0 None -501 8 Rat 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817487 1729 0 None -20 4 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6130 1729 0 None -20 4 Human 7.2 pKi = 7.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
101927062 1716 22 None -181 6 Rat 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817445 1716 22 None -181 6 Rat 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133823 1716 22 None -181 6 Rat 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3592 1716 22 None -181 6 Rat 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
44584852 1716 22 None -181 6 Rat 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6090 1716 22 None -181 6 Rat 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
91898917 1716 22 None -181 6 Rat 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
CHEMBL506553 1716 22 None -181 6 Rat 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6100 2449 0 None -213 3 Human 7.3 pKi = 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None None
3896 2443 0 None -380 7 Human 7.4 pKi = 7.4 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3896 2443 0 None -380 7 Human 7.4 pKi = 7.4 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817479 1736 0 None -14 6 Human 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817479 1736 0 None -14 6 Human 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6083 1736 0 None -14 6 Human 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6083 1736 0 None -14 6 Human 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817479 1736 0 None -12 6 Rat 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6083 1736 0 None -12 6 Rat 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3896 2443 0 None -281 7 Rat 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
3896 2443 0 None -281 7 Rat 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3896 2443 0 None -281 7 Rat 7.5 pKi = 7.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6146 337 0 None - 1 Rat 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6127 1761 0 None 575 3 Rat 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 397 3 0 4 5.2 COc1ccc(cn1)N1C(=O)/C(=N/c2ccc(c(c2)Cl)Cl)/c2c1cccc2 15944002
9800980 1761 0 None 575 3 Rat 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 397 3 0 4 5.2 COc1ccc(cn1)N1C(=O)/C(=N/c2ccc(c(c2)Cl)Cl)/c2c1cccc2 15944002
1471834 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16287967
1471834 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16730981
1471834 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16789730
6126 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16287967
6126 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16730981
6126 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16789730
CHEMBL210288 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16287967
CHEMBL210288 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16730981
CHEMBL210288 3629 42 None 4 3 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16789730
3898 2446 0 None -63 7 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3898 2446 0 None -63 7 Human 7.8 pKi = 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6076 2109 0 None -2 3 Human 7.9 pKi = 7.9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23600864
155817465 1730 0 None -13 6 Rat 7.9 pKi = 7.9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817465 1730 0 None -13 6 Rat 7.9 pKi = 7.9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
3876 1730 0 None -13 6 Rat 7.9 pKi = 7.9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3876 1730 0 None -13 6 Rat 7.9 pKi = 7.9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
155817484 1714 0 None -22 6 Human 8.0 pKi = 8.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817484 1714 0 None -22 6 Human 8.0 pKi = 8.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6117 1714 0 None -22 6 Human 8.0 pKi = 8.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6117 1714 0 None -22 6 Human 8.0 pKi = 8.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6129 1714 0 None -22 6 Human 8.0 pKi = 8.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6129 1714 0 None -22 6 Human 8.0 pKi = 8.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817463 777 0 None -34 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817463 777 0 None -34 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
3861 777 0 None -34 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3861 777 0 None -34 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
16133243 1715 0 None -51 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
16133243 1715 0 None -51 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
16133243 1715 0 None -51 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133243 1715 0 None -51 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
3593 1715 0 None -51 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
3593 1715 0 None -51 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
3593 1715 0 None -51 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3593 1715 0 None -51 8 Human 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817484 1714 0 None -10 6 Rat 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6117 1714 0 None -10 6 Rat 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6129 1714 0 None -10 6 Rat 8.1 pKi = 8.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6139 1726 0 None -1 2 Rat 8.2 pKi = 8.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3897 2445 0 None -27 6 Human 8.2 pKi = 8.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3897 2445 0 None -27 6 Human 8.2 pKi = 8.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
11698643 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16287967
11698643 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16730981
11698643 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16789730
6125 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16287967
6125 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16730981
6125 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16789730
CHEMBL209497 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16287967
CHEMBL209497 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16730981
CHEMBL209497 3630 11 None 15 4 Human 8.3 pKi = 8.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16789730
3898 2446 0 None -16 7 Rat 8.4 pKi = 8.4 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
3898 2446 0 None -16 7 Rat 8.4 pKi = 8.4 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3898 2446 0 None -16 7 Rat 8.4 pKi = 8.4 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133243 1715 0 None -22 8 Rat 8.5 pKi = 8.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
16133243 1715 0 None -22 8 Rat 8.5 pKi = 8.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
16133243 1715 0 None -22 8 Rat 8.5 pKi = 8.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133243 1715 0 None -22 8 Rat 8.5 pKi = 8.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
3593 1715 0 None -22 8 Rat 8.5 pKi = 8.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
3593 1715 0 None -22 8 Rat 8.5 pKi = 8.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3593 1715 0 None -22 8 Rat 8.5 pKi = 8.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3593 1715 0 None -22 8 Rat 8.5 pKi = 8.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
155817463 777 0 None -7 8 Rat 8.7 pKi = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817463 777 0 None -7 8 Rat 8.7 pKi = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3861 777 0 None -7 8 Rat 8.7 pKi = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3861 777 0 None -7 8 Rat 8.7 pKi = 8.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3897 2445 0 None -5 6 Rat 8.9 pKi = 8.9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6074 2442 0 None -301 3 Human 5.0 pKi > 5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23192661
3900 2451 0 None -758 3 Human 5.0 pKi > 5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None None
6133 1494 0 None 1 2 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817483 1717 0 None -1 2 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6094 1717 0 None -1 2 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817480 1731 0 None -1 6 Human 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817480 1731 0 None -1 6 Human 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817480 1731 0 None -1 6 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6091 1731 0 None -1 6 Human 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6091 1731 0 None -1 6 Human 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6091 1731 0 None -1 6 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817481 1732 0 None -1 6 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817481 1732 0 None -1 6 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
6092 1732 0 None -1 6 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6092 1732 0 None -1 6 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
6095 1739 0 None -72 6 Human 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6095 1739 0 None -72 6 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6095 1739 0 None -72 6 Rat 6.0 pKi > 6 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084