Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 1324 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| 16154396 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| 16197727 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| 16197727.0 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| 44285019 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| 57514683 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| 91898441 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| CHEMBL441738 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| DB04931 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.5 | 10.5 | -5 | 8 | Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayAgonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assay |
ChEMBL | None | None | None | None | 10.1021/jm101425m | ||||
| CHEMBL2371966 | 212622 | None | 0 | Human | Functional | pEC50 | = | 10.5 | 10.5 | 616 | 4 | Agonist activity at human MC5R expressed in CHO cells assessed as cAMP accumulationAgonist activity at human MC5R expressed in CHO cells assessed as cAMP accumulation |
ChEMBL | None | None | None | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCCN2C(=O)[C@H](Cc2ccc(-c3ccccc3)cc2)NC(=O)[C@@H]2CCCN2C1=O | 10.1021/jm0614275 | ||||
| 118722937 | 116302 | None | 0 | Mouse | Functional | pEC50 | = | 10.4 | 10.4 | 1 | 3 | Activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayActivity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
ChEMBL | 1048 | 17 | 13 | 13 | -0.7 | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCCc2cn(nn2)CC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O | 10.1021/jm501027w | ||
| CHEMBL3358545 | 116302 | None | 0 | Mouse | Functional | pEC50 | = | 10.4 | 10.4 | 1 | 3 | Activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayActivity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
ChEMBL | 1048 | 17 | 13 | 13 | -0.7 | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCCc2cn(nn2)CC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O | 10.1021/jm501027w | ||
| 118722941 | 116306 | None | 0 | Mouse | Functional | pEC50 | = | 10.4 | 10.4 | 1 | 3 | Activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayActivity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
ChEMBL | 1048 | 17 | 13 | 13 | -0.7 | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCn2cc(nn2)CCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O | 10.1021/jm501027w | ||
| CHEMBL3358549 | 116306 | None | 0 | Mouse | Functional | pEC50 | = | 10.4 | 10.4 | 1 | 3 | Activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayActivity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
ChEMBL | 1048 | 17 | 13 | 13 | -0.7 | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCn2cc(nn2)CCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O | 10.1021/jm501027w | ||
| 118722933 | 116299 | None | 0 | Mouse | Functional | pEC50 | = | 10.3 | 10.3 | 1 | 3 | Activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayActivity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
ChEMBL | 1038 | 33 | 13 | 11 | 1.2 | CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCN=[N+]=[N-])NC(=O)[C@H](CCCC)NC(C)=O)C(N)=O | 10.1021/jm501027w | ||
| CHEMBL3358541 | 116299 | None | 0 | Mouse | Functional | pEC50 | = | 10.3 | 10.3 | 1 | 3 | Activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayActivity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
ChEMBL | 1038 | 33 | 13 | 11 | 1.2 | CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCN=[N+]=[N-])NC(=O)[C@H](CCCC)NC(C)=O)C(N)=O | 10.1021/jm501027w | ||
| 1324 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| 16154396 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| 16197727 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| 16197727.0 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| 44285019 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| 57514683 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| 91898441 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| CHEMBL441738 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| DB04931 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayAgonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay |
ChEMBL | None | None | None | None | 10.1021/jm0492756 | ||||
| 1324 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| 16154396 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| 16197727 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| 16197727.0 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| 44285019 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| 57514683 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| 91898441 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| CHEMBL441738 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| DB04931 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Maximum agonist response for mouse melanocortin 5 receptor (MC5R)Maximum agonist response for mouse melanocortin 5 receptor (MC5R) |
ChEMBL | None | None | None | None | 10.1021/jm030452x | ||||
| 118722944 | 116309 | None | 0 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -1 | 3 | Activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayActivity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
ChEMBL | 1034 | 17 | 13 | 13 | -1.1 | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCn2cc(nn2)CC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O | 10.1021/jm501027w | ||
| CHEMBL3358552 | 116309 | None | 0 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -1 | 3 | Activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayActivity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
ChEMBL | 1034 | 17 | 13 | 13 | -1.1 | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCn2cc(nn2)CC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O | 10.1021/jm501027w | ||
| 1324 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| 16154396 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| 16197727 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| 16197727.0 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| 44285019 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| 57514683 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| 91898441 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| CHEMBL441738 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| DB04931 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
ChEMBL | None | None | None | None | 10.1021/jm010524p | ||||
| 1324 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Effective concentration against mouse Melanocortin 5 receptorEffective concentration against mouse Melanocortin 5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm0303608 | ||||
| 16154396 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Effective concentration against mouse Melanocortin 5 receptorEffective concentration against mouse Melanocortin 5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm0303608 | ||||
| 16197727 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Effective concentration against mouse Melanocortin 5 receptorEffective concentration against mouse Melanocortin 5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm0303608 | ||||
| 16197727.0 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Effective concentration against mouse Melanocortin 5 receptorEffective concentration against mouse Melanocortin 5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm0303608 | ||||
| 44285019 | 302 | None | 19 | Mouse | Functional | pEC50 | = | 10.2 | 10.2 | -5 | 8 | Effective concentration against mouse Melanocortin 5 receptorEffective concentration against mouse Melanocortin 5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm0303608 | ||||
Showing 1 to 50 of 1,673 entries
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 44366081 | 10264 | None | 0 | Human | Binding | pEC50 | = | 10.5 | 10.5 | - | 2 | Binding affinity against human Melanocortin 5 receptorBinding affinity against human Melanocortin 5 receptor |
ChEMBL | 1036 | 15 | 13 | 11 | 0.4 | CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(O)[C@H]2CCCN2C1=O | 10.1021/jm0202526 | ||
| CHEMBL1161313 | 10264 | None | 0 | Human | Binding | pEC50 | = | 10.5 | 10.5 | - | 2 | Binding affinity against human Melanocortin 5 receptorBinding affinity against human Melanocortin 5 receptor |
ChEMBL | 1036 | 15 | 13 | 11 | 0.4 | CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(O)[C@H]2CCCN2C1=O | 10.1021/jm0202526 | ||
| 1323 | 2688 | None | 38 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| 92432 | 2688 | None | 38 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| CHEMBL430239 | 2688 | None | 38 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| 1324 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 16154396 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 16197727 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 16197727.0 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 44285019 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 57514683 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 91898441 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| CHEMBL441738 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| DB04931 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 1324 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| 16154396 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| 16197727 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| 16197727.0 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| 44285019 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| 57514683 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| 91898441 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| CHEMBL441738 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| DB04931 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.2 | 10.2 | - | 4 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | None | None | None | None | 10.1021/jm0104872 | ||||
| 101176453 | 183068 | None | 0 | Human | Binding | pEC50 | = | 10.1 | 10.1 | - | 0 | Agonist activity at human melanocortin receptor 5Agonist activity at human melanocortin receptor 5 |
ChEMBL | 1034 | 15 | 12 | 10 | 0.7 | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H]2CCCN2C1=O | 10.1021/acs.jmedchem.6b01029 | ||
| CHEMBL4792986 | 183068 | None | 0 | Human | Binding | pEC50 | = | 10.1 | 10.1 | - | 0 | Agonist activity at human melanocortin receptor 5Agonist activity at human melanocortin receptor 5 |
ChEMBL | 1034 | 15 | 12 | 10 | 0.7 | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H]2CCCN2C1=O | 10.1021/acs.jmedchem.6b01029 | ||
| CHEMBL1161322 | 210967 | None | 0 | Human | Binding | pEC50 | = | 10.1 | 10.1 | - | 2 | Binding affinity against human Melanocortin 5 receptorBinding affinity against human Melanocortin 5 receptor |
ChEMBL | None | None | None | CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H]2CCCN2C1=O | 10.1021/jm0202526 | ||||
| 1324 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| 16154396 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| 16197727 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| 16197727.0 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| 44285019 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| 57514683 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| 91898441 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| CHEMBL441738 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| DB04931 | 302 | None | 19 | Mouse | Binding | pEC50 | = | 10.0 | 10.0 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | None | 10.1021/jm049010r | ||||
| CHEMBL2096742 | 211665 | None | 0 | Human | Binding | pEC50 | = | 9.9 | 9.9 | - | 2 | Binding affinity against human Melanocortin 5 receptorBinding affinity against human Melanocortin 5 receptor |
ChEMBL | None | None | None | CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O | 10.1021/jm0202526 | ||||
| CHEMBL442504 | 216377 | None | 0 | Human | Binding | pEC50 | = | 9.9 | 9.9 | -1 | 3 | Signal transduction efficacy in cAMP assay in CHO cells expressing human melanocortin receptor 5Signal transduction efficacy in cAMP assay in CHO cells expressing human melanocortin receptor 5 |
ChEMBL | None | None | None | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](C(N)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O | 10.1021/jm010165y | ||||
| 1323 | 2688 | None | 38 | Mouse | Binding | pEC50 | = | 9.8 | 9.8 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 92432 | 2688 | None | 38 | Mouse | Binding | pEC50 | = | 9.8 | 9.8 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| CHEMBL430239 | 2688 | None | 38 | Mouse | Binding | pEC50 | = | 9.8 | 9.8 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | None | 10.1021/jm020296e | ||||
| 44327392 | 141950 | None | 0 | Mouse | Binding | pEC50 | = | 9.8 | 9.8 | - | 0 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | 1025 | 21 | 12 | 12 | -0.6 | CCCC[C@H](NC(C)=O)C(=O)N1C(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]cn2)NC(=O)[C@@H]1CC(=O)O | 10.1021/jm0104872 | ||
| CHEMBL386583 | 141950 | None | 0 | Mouse | Binding | pEC50 | = | 9.8 | 9.8 | - | 0 | In vitro activation of mouse recombinant Melanocortin-5 receptor.In vitro activation of mouse recombinant Melanocortin-5 receptor. |
ChEMBL | 1025 | 21 | 12 | 12 | -0.6 | CCCC[C@H](NC(C)=O)C(=O)N1C(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]cn2)NC(=O)[C@@H]1CC(=O)O | 10.1021/jm0104872 | ||
| CHEMBL1161323 | 210968 | None | 0 | Human | Binding | pEC50 | = | 9.7 | 9.7 | - | 2 | Binding affinity against human Melanocortin 5 receptorBinding affinity against human Melanocortin 5 receptor |
ChEMBL | None | None | None | CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H]2C[C@@]3(C)CCCC[C@@]3(C)N2C1=O | 10.1021/jm0202526 | ||||
| 16132144 | 211738 | None | 29 | Mouse | Binding | pEC50 | = | 9.5 | 9.5 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C | 10.1021/jm049010r | ||||
| 16133793 | 211738 | None | 29 | Mouse | Binding | pEC50 | = | 9.5 | 9.5 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C | 10.1021/jm049010r | ||||
| 44273719 | 211738 | None | 29 | Mouse | Binding | pEC50 | = | 9.5 | 9.5 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C | 10.1021/jm049010r | ||||
| CHEMBL214332 | 211738 | None | 29 | Mouse | Binding | pEC50 | = | 9.5 | 9.5 | - | 4 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C | 10.1021/jm049010r | ||||
| CHEMBL2369959 | 212199 | None | 0 | Mouse | Binding | pEC50 | = | 9.4 | 9.4 | - | 0 | Effective concentration for mouse Melanocortin-5 receptorEffective concentration for mouse Melanocortin-5 receptor |
ChEMBL | None | None | None | C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)[C@@](C)(C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O | 10.1021/jm049010r | ||||
| 16132144 | 211738 | None | 29 | Mouse | Binding | pEC50 | = | 9.4 | 9.4 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C | 10.1021/jm020296e | ||||
| 16133793 | 211738 | None | 29 | Mouse | Binding | pEC50 | = | 9.4 | 9.4 | - | 4 | Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsActivity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
ChEMBL | None | None | None | CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C | 10.1021/jm020296e | ||||
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