Ligand source activities (1 row/activity)





Ligands Receptor Assay information Chemical information
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GPCRdb ID #Vendors Reference
ligand
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Type Activity
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Activity
Value
Assay Type Assay Description Source Mol
weight
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H don H acc LogP Smiles DOI
90012275 133626 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 416 6 2 3 5.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(C)(C)C)c1 nan
CHEMBL3714858 133626 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 416 6 2 3 5.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(C)(C)C)c1 nan
56593334 134096 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716462 134096 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90011833 134276 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc([N+](=O)[O-])c1 nan
CHEMBL3717071 134276 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc([N+](=O)[O-])c1 nan
56593330 134361 0 None - 1 Human 6.9 pAC50 = 6.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717389 134361 0 None - 1 Human 6.9 pAC50 = 6.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593346 134306 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F nan
CHEMBL3717178 134306 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F nan
90010727 133789 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 487 6 2 4 4.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cncc(I)c1 nan
CHEMBL3715451 133789 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 487 6 2 4 4.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cncc(I)c1 nan
118037864 133857 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 3 3 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2nc[nH]c12 nan
CHEMBL3715676 133857 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 3 3 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2nc[nH]c12 nan
2806493 134093 4 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 nan
CHEMBL3716450 134093 4 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 nan
118037922 134661 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 612 8 2 6 6.1 CC(C)(C)OC(=O)N1CCN(CCOc2ccccc2C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
CHEMBL3718384 134661 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 612 8 2 6 6.1 CC(C)(C)OC(=O)N1CCN(CCOc2ccccc2C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
90010869 134840 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 392 6 2 4 4.9 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC)c1 nan
CHEMBL3718995 134840 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 392 6 2 4 4.9 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC)c1 nan
38269206 134655 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718363 134655 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90010751 134347 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C\c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
CHEMBL3717338 134347 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C\c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
90012348 134561 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc([N+](=O)[O-])cc1 nan
CHEMBL3718077 134561 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc([N+](=O)[O-])cc1 nan
90010773 133886 0 None -1 2 Human 4.8 pAC50 = 4.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 375 4 2 4 4.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccno1 nan
CHEMBL3715750 133886 0 None -1 2 Human 4.8 pAC50 = 4.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 375 4 2 4 4.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccno1 nan
90011033 134848 0 None - 1 Human 4.8 pAC50 = 4.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2ccccc2c1 nan
CHEMBL3719015 134848 0 None - 1 Human 4.8 pAC50 = 4.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2ccccc2c1 nan
56593309 133737 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715203 133737 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90011788 133801 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3715489 133801 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
90012098 134555 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Br)c1 nan
CHEMBL3718061 134555 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Br)c1 nan
56593314 134315 0 None - 1 Human 6.7 pAC50 = 6.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717211 134315 0 None - 1 Human 6.7 pAC50 = 6.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593340 134075 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3716394 134075 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1313624 134423 8 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Cl)c1 nan
CHEMBL3717590 134423 8 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Cl)c1 nan
56593311 134462 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717723 134462 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
24671974 134767 2 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 3 5.3 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccs1 nan
CHEMBL3718728 134767 2 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 3 5.3 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccs1 nan
90012130 133660 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3714976 133660 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
90010778 134188 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C/c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
CHEMBL3716808 134188 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C/c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
56593317 134923 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 nan
CHEMBL3719257 134923 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 nan
40622265 133855 2 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 374 4 2 3 4.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccco1 nan
CHEMBL3715664 133855 2 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 374 4 2 3 4.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccco1 nan
127024729 134451 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 500 7 2 6 4.0 CCOc1ccccc1C(=O)NC1SC=CC1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717683 134451 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 500 7 2 6 4.0 CCOc1ccccc1C(=O)NC1SC=CC1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010630 134772 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.7 CC1CCC(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
CHEMBL3718740 134772 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.7 CC1CCC(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
5298634 134933 10 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 nan
CHEMBL3719295 134933 10 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 nan
56593335 134280 0 None - 1 Human 6.6 pAC50 = 6.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717089 134280 0 None - 1 Human 6.6 pAC50 = 6.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011775 133647 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)cc1 nan
CHEMBL3714926 133647 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)cc1 nan
90011735 133745 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 511 8 2 4 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCCCC1 nan
CHEMBL3715244 133745 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 511 8 2 4 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCCCC1 nan
56593308 134134 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716596 134134 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593324 134191 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 8 2 5 5.2 CCOc1ccccc1C(=O)Nc1ccccc1CNc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3716811 134191 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 8 2 5 5.2 CCOc1ccccc1C(=O)Nc1ccccc1CNc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593333 134210 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716871 134210 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593350 134622 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3718273 134622 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
56593315 134287 0 None - 1 Human 6.5 pAC50 = 6.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3717103 134287 0 None - 1 Human 6.5 pAC50 = 6.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
90010752 133670 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 448 4 2 2 5.1 O=C(Nc1cccc(I)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3714999 133670 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 448 4 2 2 5.1 O=C(Nc1cccc(I)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90011874 133687 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1 nan
CHEMBL3715040 133687 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1 nan
56593323 133711 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715105 133711 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593318 134107 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 nan
CHEMBL3716512 134107 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 nan
90010791 134247 0 None - 1 Human 4.5 pAC50 = 4.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccccn1 nan
CHEMBL3716987 134247 0 None - 1 Human 4.5 pAC50 = 4.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccccn1 nan
56593313 134826 0 None - 1 Human 4.5 pAC50 = 4.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 nan
CHEMBL3718895 134826 0 None - 1 Human 4.5 pAC50 = 4.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 nan
56593329 134408 0 None - 1 Human 6.5 pAC50 = 6.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717553 134408 0 None - 1 Human 6.5 pAC50 = 6.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593336 133818 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715551 133818 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593337 133707 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl nan
CHEMBL3715097 133707 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl nan
127024591 133718 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 457 8 3 4 4.8 CNCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715139 133718 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 457 8 3 4 4.8 CNCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
2233108 134444 9 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3717655 134444 9 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1511185 133812 12 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3715535 133812 12 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
4795548 134212 5 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3716878 134212 5 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
32157880 134218 4 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1ccc(F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716901 134218 4 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1ccc(F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
90010785 133662 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 574 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1I nan
CHEMBL3714984 133662 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 574 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1I nan
118043134 133710 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 4 2 2 7.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
CHEMBL3715104 133710 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 4 2 2 7.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
21179517 133924 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 2 2 6.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715901 133924 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 2 2 6.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1cccc(C(F)(F)F)c1 nan
56593306 134269 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717045 134269 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90012794 134487 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Br)cc1 nan
CHEMBL3717803 134487 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Br)cc1 nan
54784887 134657 2 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1ccccc1 nan
CHEMBL3718373 134657 2 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1ccccc1 nan
1313916 40066 8 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1479446 40066 8 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593322 133700 0 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715081 133700 0 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593331 134701 0 None - 1 Human 6.3 pAC50 = 6.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718541 134701 0 None - 1 Human 6.3 pAC50 = 6.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011206 133784 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 513 8 2 5 4.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCOCC1 nan
CHEMBL3715429 133784 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 513 8 2 5 4.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCOCC1 nan
56593347 133814 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715539 133814 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010797 133840 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 4 2 2 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C12CC3CC(CC(C3)C1)C2 nan
CHEMBL3715615 133840 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 4 2 2 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C12CC3CC(CC(C3)C1)C2 nan
4484023 134244 6 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3716976 134244 6 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
56593338 134706 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 8 2 5 3.1 CCOc1ccccc1C(=O)NCCC(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3718557 134706 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 8 2 5 3.1 CCOc1ccccc1C(=O)NCCC(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593307 134796 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 386 5 2 3 5.7 COc1ccccc1Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718811 134796 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 386 5 2 3 5.7 COc1ccccc1Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011315 134180 0 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 370 5 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccccc1 nan
CHEMBL3716765 134180 0 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 370 5 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccccc1 nan
127024076 134464 1 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 308 4 2 2 3.5 O=CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717734 134464 1 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 308 4 2 2 3.5 O=CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010896 134504 0 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 438 5 2 2 6.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1cccc(C(F)(F)F)c1 nan
CHEMBL3717869 134504 0 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 438 5 2 2 6.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1cccc(C(F)(F)F)c1 nan
56593316 133743 0 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715235 133743 0 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593341 133810 0 None - 1 Human 6.3 pAC50 = 6.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 508 7 2 5 5.6 CCSc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715526 133810 0 None - 1 Human 6.3 pAC50 = 6.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 508 7 2 5 5.6 CCSc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010758 133792 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 5 2 2 6.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccccc2)c1 nan
CHEMBL3715462 133792 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 5 2 2 6.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccccc2)c1 nan
56593299 133988 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3716127 133988 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
56593339 134100 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716488 134100 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593319 134192 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716813 134192 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010729 134198 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 6 2 4 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(N2CCCCC2)c1 nan
CHEMBL3716829 134198 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 6 2 4 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(N2CCCCC2)c1 nan
90010865 134697 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 380 3 2 3 5.3 CC(C)(C)OC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718514 134697 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 380 3 2 3 5.3 CC(C)(C)OC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010599 134937 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 5 2 2 5.6 CC(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3719301 134937 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 5 2 2 5.6 CC(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
90011364 134034 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 5 2 2 6.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCC1CCCCC1 nan
CHEMBL3716260 134034 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 5 2 2 6.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCC1CCCCC1 nan
90011496 134124 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2ccccc12 nan
CHEMBL3716563 134124 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2ccccc12 nan
90011579 134245 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1 nan
CHEMBL3716978 134245 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1 nan
56593303 134592 1 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 nan
CHEMBL3718178 134592 1 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 nan
60288826 134623 1 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 426 5 2 3 5.4 CC(=O)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3718279 134623 1 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 426 5 2 3 5.4 CC(=O)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
56593326 134722 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718612 134722 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593302 133751 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715266 133751 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011338 133767 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 485 9 2 4 5.5 CN(C)CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715346 133767 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 485 9 2 4 5.5 CN(C)CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593298 134457 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 6 2 3 5.6 COc1ccccc1CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717700 134457 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 6 2 3 5.6 COc1ccccc1CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010708 134270 0 None - 1 Human 6.2 pAC50 = 6.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 6 2 4 4.5 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C#N)c1 nan
CHEMBL3717047 134270 0 None - 1 Human 6.2 pAC50 = 6.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 6 2 4 4.5 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C#N)c1 nan
118043136 134900 0 None - 1 Human 6.2 pAC50 = 6.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 7 2 4 6.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3719197 134900 0 None - 1 Human 6.2 pAC50 = 6.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 7 2 4 6.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
90010848 133709 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 6 2 5 3.6 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(C)(=O)=O)c1 nan
CHEMBL3715101 133709 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 6 2 5 3.6 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(C)(=O)=O)c1 nan
90010777 134552 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 346 4 2 2 4.4 C#Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3718054 134552 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 346 4 2 2 4.4 C#Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
118037818 134684 0 None -1 2 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 4 2 4 4.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2 nan
CHEMBL3718470 134684 0 None -1 2 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 4 2 4 4.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2 nan
56593305 134665 0 None - 1 Human 7.2 pAC50 = 7.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
CHEMBL3718400 134665 0 None - 1 Human 7.2 pAC50 = 7.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
90010645 133766 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 486 6 2 3 5.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(I)c1 nan
CHEMBL3715345 133766 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 486 6 2 3 5.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(I)c1 nan
56593345 133882 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715743 133882 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593320 134117 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716540 134117 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011367 134749 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 476 6 2 3 7.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1Oc1ccccc1 nan
CHEMBL3718664 134749 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 476 6 2 3 7.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1Oc1ccccc1 nan
56593296 134132 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716581 134132 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011087 134248 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1C(F)(F)F nan
CHEMBL3716990 134248 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1C(F)(F)F nan
90011219 134633 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 510 4 2 2 5.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1I nan
CHEMBL3718291 134633 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 510 4 2 2 5.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1I nan
90011247 134691 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Br nan
CHEMBL3718498 134691 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Br nan
52764307 134843 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccncc1 nan
CHEMBL3719005 134843 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccncc1 nan
90010748 133712 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1ccc([N+](=O)[O-])cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715107 133712 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1ccc([N+](=O)[O-])cc1)c1ccccc1NC(=O)C1CCCCC1 nan
90010731 133869 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccncc1 nan
CHEMBL3715708 133869 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccncc1 nan
3348337 134424 1 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 3 2 2 3.9 CC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717591 134424 1 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 3 2 2 3.9 CC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
29448220 134837 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 366 4 2 4 4.2 O=C(Nc1ccc2c(c1)OCO2)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718975 134837 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 366 4 2 4 4.2 O=C(Nc1ccc2c(c1)OCO2)c1ccccc1NC(=O)C1CCCCC1 nan
56593344 133672 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715001 133672 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593325 134742 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 nan
CHEMBL3718643 134742 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 nan
56593349 2554 30 None - 1 Human 7.0 pAC50 = 7.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
8322 2554 30 None - 1 Human 7.0 pAC50 = 7.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
CHEMBL3716980 2554 30 None - 1 Human 7.0 pAC50 = 7.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
90011702 133727 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.9 O=C(Nc1ccc2c(c1)CCC2)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715166 133727 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.9 O=C(Nc1ccc2c(c1)CCC2)c1ccccc1NC(=O)C1CCCCC1 nan
56593321 134461 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717718 134461 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 nan
90011489 134574 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 6 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCCc1ccccc1 nan
CHEMBL3718114 134574 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 6 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCCc1ccccc1 nan
60589025 134770 1 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 5 2 4 4.6 CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3718735 134770 1 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 5 2 4 4.6 CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1320335 134797 9 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3718813 134797 9 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
730108 41509 17 None - 1 Human 4.0 pAC50 = 4.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1491180 41509 17 None - 1 Human 4.0 pAC50 = 4.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 nan
56593342 134392 0 None - 1 Human 4.0 pAC50 = 4.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717485 134392 0 None - 1 Human 4.0 pAC50 = 4.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
162654489 180611 0 None 4 2 Human 10.5 pEC50 = 10.5 Functional
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180611 0 None 4 2 Human 10.5 pEC50 = 10.5 Functional
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162648163 179849 0 None - 1 Human 10.0 pEC50 = 10 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4745611 179849 0 None - 1 Human 10.0 pEC50 = 10 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672427 183175 0 None - 1 Human 9.7 pEC50 = 9.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4795810 183175 0 None - 1 Human 9.7 pEC50 = 9.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162667576 182460 0 None - 1 Human 9.4 pEC50 = 9.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4786789 182460 0 None - 1 Human 9.4 pEC50 = 9.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162654489 180611 0 None 4 2 Human 9.4 pEC50 = 9.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180611 0 None 4 2 Human 9.4 pEC50 = 9.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162677247 183506 0 None - 1 Human 9.2 pEC50 = 9.2 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
CHEMBL4799907 183506 0 None - 1 Human 9.2 pEC50 = 9.2 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
162661030 181425 0 None - 1 Human 9.0 pEC50 = 9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4764326 181425 0 None - 1 Human 9.0 pEC50 = 9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162674882 183328 0 None - 1 Human 9.0 pEC50 = 9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797641 183328 0 None - 1 Human 9.0 pEC50 = 9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593316 133743 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715235 133743 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593334 134096 0 None - 1 Human 6.0 pEC50 = 6.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716462 134096 0 None - 1 Human 6.0 pEC50 = 6.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593305 134665 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
CHEMBL3718400 134665 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
56593346 134306 0 None - 1 Human 5.9 pEC50 = 5.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F 10.1016/j.ejmech.2018.06.008
CHEMBL3717178 134306 0 None - 1 Human 5.9 pEC50 = 5.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F 10.1016/j.ejmech.2018.06.008
162664297 182057 0 None -2 2 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781560 182057 0 None -2 2 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593322 133700 0 None - 1 Human 6.9 pEC50 = 6.9 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715081 133700 0 None - 1 Human 6.9 pEC50 = 6.9 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
162649438 180028 0 None - 1 Human 6.9 pEC50 = 6.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3412 125 54 48 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4747756 180028 0 None - 1 Human 6.9 pEC50 = 6.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3412 125 54 48 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
2806493 134093 4 None - 1 Human 5.9 pEC50 = 5.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 10.1016/j.ejmech.2018.06.008
CHEMBL3716450 134093 4 None - 1 Human 5.9 pEC50 = 5.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 10.1016/j.ejmech.2018.06.008
38269206 134655 0 None - 1 Human 4.9 pEC50 = 4.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718363 134655 0 None - 1 Human 4.9 pEC50 = 4.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
162659815 181176 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2785 100 45 39 -13.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4761130 181176 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2785 100 45 39 -13.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162666079 182289 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2855 106 46 40 -12.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4784237 182289 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2855 106 46 40 -12.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162656358 180865 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3355 121 53 47 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4757578 180865 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3355 121 53 47 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162677445 183519 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3139 113 49 43 -12.2 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4800116 183519 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3139 113 49 43 -12.2 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593309 133737 0 None - 1 Human 5.8 pEC50 = 5.8 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715203 133737 0 None - 1 Human 5.8 pEC50 = 5.8 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162646950 179655 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3195 119 50 44 -12.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4743539 179655 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3195 119 50 44 -12.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162643258 181718 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3411 126 53 47 -12.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(C)C(=O)NCC(C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O 10.1021/acs.jmedchem.0c01533
CHEMBL4777259 181718 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3411 126 53 47 -12.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(C)C(=O)NCC(C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O 10.1021/acs.jmedchem.0c01533
162674863 183289 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3509 135 52 47 -9.4 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797258 183289 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3509 135 52 47 -9.4 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162662427 181934 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3383 123 53 47 -14.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4779982 181934 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3383 123 53 47 -14.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162648609 179791 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3292 122 50 45 -12.0 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4744987 179791 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3292 122 50 45 -12.0 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672427 183175 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4795810 183175 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593314 134315 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717211 134315 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593330 134361 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717389 134361 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
1313916 40066 8 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL1479446 40066 8 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593340 134075 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716394 134075 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 10.1016/j.ejmech.2018.06.008
56593311 134462 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717723 134462 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
162650672 180132 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3152 116 49 43 -12.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4748931 180132 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3152 116 49 43 -12.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162648163 179849 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4745611 179849 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593349 2554 30 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
8322 2554 30 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
CHEMBL3716980 2554 30 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
162659417 181202 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3257 114 52 46 -15.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4761424 181202 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3257 114 52 46 -15.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162670766 182928 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3097 111 49 43 -13.1 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4792874 182928 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3097 111 49 43 -13.1 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593317 134923 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3719257 134923 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 10.1016/j.ejmech.2018.06.008
162654519 180646 0 None - 1 Human 7.6 pEC50 = 7.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2828 103 46 40 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4755239 180646 0 None - 1 Human 7.6 pEC50 = 7.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2828 103 46 40 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162654037 180650 0 None - 1 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3424 126 53 47 -12.7 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4755289 180650 0 None - 1 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3424 126 53 47 -12.7 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
5298634 134933 10 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3719295 134933 10 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 10.1016/j.ejmech.2018.06.008
56593332 162227 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 498 7 2 6 4.9 CCOc1ccccc1C(=O)Nc1sccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL4163593 162227 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 498 7 2 6 4.9 CCOc1ccccc1C(=O)Nc1sccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162667576 182460 0 None - 1 Human 7.6 pEC50 = 7.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4786789 182460 0 None - 1 Human 7.6 pEC50 = 7.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593335 134280 0 None - 1 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717089 134280 0 None - 1 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593308 134134 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716596 134134 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593333 134210 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716871 134210 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593350 134622 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718273 134622 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
162672610 182992 0 None -35 2 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4793799 182992 0 None -35 2 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593323 133711 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715105 133711 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593318 134107 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716512 134107 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 10.1016/j.ejmech.2018.06.008
56593313 134826 0 None - 1 Human 4.5 pEC50 = 4.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718895 134826 0 None - 1 Human 4.5 pEC50 = 4.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162652974 180393 0 None - 1 Human 8.5 pEC50 = 8.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4163 175 54 60 -9.4 CCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4752287 180393 0 None - 1 Human 8.5 pEC50 = 8.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4163 175 54 60 -9.4 CCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672610 182992 0 None -35 2 Human 8.4 pEC50 = 8.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4793799 182992 0 None -35 2 Human 8.4 pEC50 = 8.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162674882 183328 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797641 183328 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162669540 182615 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2867 105 45 40 -11.9 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4788675 182615 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2867 105 45 40 -11.9 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162670803 182812 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3314 119 53 47 -14.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4791290 182812 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3314 119 53 47 -14.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593329 134408 0 None - 1 Human 6.5 pEC50 = 6.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717553 134408 0 None - 1 Human 6.5 pEC50 = 6.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593336 133818 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3715551 133818 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593314 134315 0 None - 1 Human 6.5 pEC50 = 6.5 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717211 134315 0 None - 1 Human 6.5 pEC50 = 6.5 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593330 134361 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717389 134361 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
162648114 179891 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4489 180 64 59 -8.3 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4746080 179891 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4489 180 64 59 -8.3 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162649375 180096 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3327 120 53 47 -15.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4748601 180096 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3327 120 53 47 -15.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593337 133707 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl 10.1016/j.ejmech.2018.06.008
CHEMBL3715097 133707 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl 10.1016/j.ejmech.2018.06.008
56593300 162177 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 471 8 2 4 5.2 CN(C)CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL4162685 162177 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 471 8 2 4 5.2 CN(C)CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
1511185 133812 12 None - 1 Human 4.4 pEC50 = 4.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715535 133812 12 None - 1 Human 4.4 pEC50 = 4.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
4795548 134212 5 None - 1 Human 4.4 pEC50 = 4.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716878 134212 5 None - 1 Human 4.4 pEC50 = 4.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
162646638 179690 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3055 109 49 43 -14.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4743958 179690 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3055 109 49 43 -14.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593306 134269 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717045 134269 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162644941 179376 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2883 107 46 40 -11.8 CC[C@H](C)[C@H](NC(=O)C(C)CNC(=O)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4739969 179376 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2883 107 46 40 -11.8 CC[C@H](C)[C@H](NC(=O)C(C)CNC(=O)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162649856 180115 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3481 130 54 48 -12.8 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4748830 180115 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3481 130 54 48 -12.8 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162663002 182024 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3122 115 48 43 -11.7 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781139 182024 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3122 115 48 43 -11.7 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162655145 180734 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3166 116 49 43 -11.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4756139 180734 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3166 116 49 43 -11.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
56593322 133700 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715081 133700 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
47936 193398 88 None 25 6 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 410 2 3 7 1.5 C=C[C@@]1(C)CC(=O)[C@@]2(O)[C@](C)(O1)[C@@H](OC(C)=O)[C@@H](O)[C@H]1C(C)(C)CC[C@H](O)[C@@]12C 10.1016/j.ejmech.2018.06.008
CHEMBL52606 193398 88 None 25 6 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 410 2 3 7 1.5 C=C[C@@]1(C)CC(=O)[C@@]2(O)[C@](C)(O1)[C@@H](OC(C)=O)[C@@H](O)[C@H]1C(C)(C)CC[C@H](O)[C@@]12C 10.1016/j.ejmech.2018.06.008
56593331 134701 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718541 134701 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593335 134280 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717089 134280 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593347 133814 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715539 133814 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162654330 179730 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3299 116 52 46 -14.6 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4744303 179730 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3299 116 52 46 -14.6 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593316 133743 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715235 133743 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162654892 180596 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3083 110 49 43 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4754697 180596 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3083 110 49 43 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593315 134287 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3717103 134287 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
56593299 133988 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716127 133988 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
56593339 134100 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716488 134100 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593319 134192 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716813 134192 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162670817 182825 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3209 121 50 44 -11.0 CC[C@H](C)[C@H](NC[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4791486 182825 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3209 121 50 44 -11.0 CC[C@H](C)[C@H](NC[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
56593303 134592 1 None - 1 Human 5.2 pEC50 = 5.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 10.1016/j.ejmech.2018.06.008
CHEMBL3718178 134592 1 None - 1 Human 5.2 pEC50 = 5.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 10.1016/j.ejmech.2018.06.008
56593326 134722 0 None - 1 Human 5.2 pEC50 = 5.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718612 134722 0 None - 1 Human 5.2 pEC50 = 5.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593302 133751 0 None - 1 Human 4.2 pEC50 = 4.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715266 133751 0 None - 1 Human 4.2 pEC50 = 4.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593305 134665 0 None - 1 Human 7.2 pEC50 = 7.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F 10.1016/j.ejmech.2018.06.008
CHEMBL3718400 134665 0 None - 1 Human 7.2 pEC50 = 7.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F 10.1016/j.ejmech.2018.06.008
162656612 180893 0 None - 1 Human 6.2 pEC50 = 6.2 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3041 106 48 42 -13.3 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4757890 180893 0 None - 1 Human 6.2 pEC50 = 6.2 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3041 106 48 42 -13.3 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593345 133882 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715743 133882 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593320 134117 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716540 134117 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593296 134132 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716581 134132 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162662592 181945 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4780098 181945 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162675717 183253 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4461 178 64 59 -9.0 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4796713 183253 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4461 178 64 59 -9.0 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593344 133672 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715001 133672 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593325 134742 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718643 134742 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 10.1016/j.ejmech.2018.06.008
162661030 181425 0 None - 1 Human 7.1 pEC50 = 7.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4764326 181425 0 None - 1 Human 7.1 pEC50 = 7.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162661521 181506 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3341 120 53 47 -14.6 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4765167 181506 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3341 120 53 47 -14.6 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162677247 183506 0 None - 1 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
CHEMBL4799907 183506 0 None - 1 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
162666829 182401 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3069 110 49 43 -13.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4785899 182401 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3069 110 49 43 -13.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162664515 182051 0 None - 1 Human 6.0 pEC50 = 6.0 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3027 105 48 42 -13.5 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781482 182051 0 None - 1 Human 6.0 pEC50 = 6.0 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3027 105 48 42 -13.5 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593349 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
8322 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
CHEMBL3716980 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
56593321 134461 0 None - 1 Human 5.0 pEC50 = 5.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717718 134461 0 None - 1 Human 5.0 pEC50 = 5.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
1320335 134797 9 None - 1 Human 5.0 pEC50 = 5.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 10.1016/j.ejmech.2018.06.008
CHEMBL3718813 134797 9 None - 1 Human 5.0 pEC50 = 5.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 10.1016/j.ejmech.2018.06.008
730108 41509 17 None - 1 Human 4.0 pEC50 = 4.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL1491180 41509 17 None - 1 Human 4.0 pEC50 = 4.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593342 134392 0 None - 1 Human 4.0 pEC50 = 4.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717485 134392 0 None - 1 Human 4.0 pEC50 = 4.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
820020 21794 7 None - 1 Human 7.0 pPotency = 7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 2 2 3 1.6 O=C(NN=C1CCCC1)c1[nH]nc2c1CCC2 nan
CHEMBL1319564 21794 7 None - 1 Human 7.0 pPotency = 7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 2 2 3 1.6 O=C(NN=C1CCCC1)c1[nH]nc2c1CCC2 nan
2146184 44536 10 None - 1 Human 7.0 pPotency = 7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 4 2.4 CN(C)c1ccc(C(=S)N2CCN(S(=O)(=O)c3ccccc3)CC2)cc1 nan
CHEMBL1519935 44536 10 None - 1 Human 7.0 pPotency = 7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 4 2.4 CN(C)c1ccc(C(=S)N2CCN(S(=O)(=O)c3ccccc3)CC2)cc1 nan
1761 99648 10 None - 1 Human 6.0 pPotency = 6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 4 9 -1.7 Nc1ncnc2c1ncn2C1OC(C(=O)NC2CC2)C(O)C1O nan
CHEMBL28449 99648 10 None - 1 Human 6.0 pPotency = 6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 4 9 -1.7 Nc1ncnc2c1ncn2C1OC(C(=O)NC2CC2)C(O)C1O nan
16019574 10849 11 None -14 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(F)cc1)c1sccc12 nan
CHEMBL1172596 10849 11 None -14 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(F)cc1)c1sccc12 nan
4132952 19639 1 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 11 0.2 CCOP1(=O)OCC2OC(n3cnc4c(N)ncnc43)C(O)C2O1 nan
CHEMBL1300691 19639 1 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 11 0.2 CCOP1(=O)OCC2OC(n3cnc4c(N)ncnc43)C(O)C2O1 nan
54677759 21058 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 3 4.1 O=c1c(Cc2ccccc2)c(O)c2cccc3c4c(n1c23)CCCC4 nan
CHEMBL1312172 21058 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 3 4.1 O=c1c(Cc2ccccc2)c(O)c2cccc3c4c(n1c23)CCCC4 nan
16027480 21491 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
CHEMBL1316197 21491 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
941768 22059 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 3 7 -0.5 O=C1NC(=O)C(=NNc2ccc3c(c2)COC3=O)C(=O)N1 nan
CHEMBL1321879 22059 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 3 7 -0.5 O=C1NC(=O)C(=NNc2ccc3c(c2)COC3=O)C(=O)N1 nan
2764158 22615 30 None -2 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 2 1 5 2.7 CSc1ccccc1-c1nnc(S)o1 nan
CHEMBL1326901 22615 30 None -2 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 2 1 5 2.7 CSc1ccccc1-c1nnc(S)o1 nan
2810145 25904 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 3.6 COc1cc2nc(NC(=O)c3ccc(Cl)cc3)sc(=O)c2cc1OC nan
CHEMBL1354031 25904 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 3.6 COc1cc2nc(NC(=O)c3ccc(Cl)cc3)sc(=O)c2cc1OC nan
16010496 26078 2 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 6 0.6 Cc1ccc2ncc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c(=O)n2c1 nan
CHEMBL1356009 26078 2 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 6 0.6 Cc1ccc2ncc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c(=O)n2c1 nan
2140949 26079 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 7 4.8 COc1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1OC nan
CHEMBL1356037 26079 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 7 4.8 COc1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1OC nan
2137373 27225 15 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 7 4.5 Cc1cccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccccc23)c1C nan
CHEMBL1366864 27225 15 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 7 4.5 Cc1cccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccccc23)c1C nan
16027547 27513 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 8 4.5 CC(C)CC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CCCCC4)sc3n2)cc1 nan
CHEMBL1369113 27513 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 8 4.5 CC(C)CC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CCCCC4)sc3n2)cc1 nan
16009802 27847 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 5 4.9 CCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
CHEMBL1371530 27847 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 5 4.9 CCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
17581362 28803 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1cccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)c1 nan
CHEMBL1379032 28803 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1cccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)c1 nan
4875840 29606 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 2 4 2.5 COc1ccc(CNC(=O)CN2C(=O)NC(C)(c3cccc(Br)c3)C2=O)cc1 nan
CHEMBL1386021 29606 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 2 4 2.5 COc1ccc(CNC(=O)CN2C(=O)NC(C)(c3cccc(Br)c3)C2=O)cc1 nan
1486264 29974 14 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 Cc1ccc(Sc2ccc(NC(=O)c3ccc(S(C)(=O)=O)cc3Cl)cc2)cc1 nan
CHEMBL1388862 29974 14 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 Cc1ccc(Sc2ccc(NC(=O)c3ccc(S(C)(=O)=O)cc3Cl)cc2)cc1 nan
2810230 30404 6 None 2 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 1 4 3.9 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)C1CCC1 nan
CHEMBL1392489 30404 6 None 2 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 1 4 3.9 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)C1CCC1 nan
16012884 30885 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 7 3.1 COc1ccc(-n2ncc3c2ncn2nc(Cc4ccccc4)nc32)cc1 nan
CHEMBL1397962 30885 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 7 3.1 COc1ccc(-n2ncc3c2ncn2nc(Cc4ccccc4)nc32)cc1 nan
16021838 30915 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cccc(Cl)c2C)c(-c2ccccc2)n1 nan
CHEMBL1398407 30915 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cccc(Cl)c2C)c(-c2ccccc2)n1 nan
2135605 31092 13 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 4.6 c1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
CHEMBL1400053 31092 13 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 4.6 c1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
15990902 31816 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 2 3 5.7 Cc1cc(C)cc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
CHEMBL1406771 31816 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 2 3 5.7 Cc1cc(C)cc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
963186 32244 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 3 4.2 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)cc1 nan
CHEMBL1410023 32244 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 3 4.2 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)cc1 nan
15989908 32246 9 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1410062 32246 9 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
15988850 32347 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 3.6 O=C(Nc1ccc(F)cc1F)c1cc(-c2ccc3c(c2)OCO3)on1 nan
CHEMBL1410908 32347 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 3.6 O=C(Nc1ccc(F)cc1F)c1cc(-c2ccc3c(c2)OCO3)on1 nan
1128972 32455 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 0 5 4.3 CCOC(=O)CSc1nc(-c2ccccc2)cc(C(F)(F)F)c1C#N nan
CHEMBL1411854 32455 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 0 5 4.3 CCOC(=O)CSc1nc(-c2ccccc2)cc(C(F)(F)F)c1C#N nan
3361436 34225 2 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 4 4 4.2 Cc1ccc(NC(=S)NC(=O)c2ccccc2)cc1NC(=S)NC(=O)c1ccccc1 nan
CHEMBL1426572 34225 2 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 4 4 4.2 Cc1ccc(NC(=S)NC(=O)c2ccccc2)cc1NC(=S)NC(=O)c1ccccc1 nan
1627636 34904 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 6 1.6 NN=C(S)Nc1cccc(-c2nnc(S)o2)c1 nan
CHEMBL1432353 34904 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 6 1.6 NN=C(S)Nc1cccc(-c2nnc(S)o2)c1 nan
8087251 35056 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccc(F)cc2)CC1 nan
CHEMBL1433615 35056 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccc(F)cc2)CC1 nan
16023146 35215 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 7 4.9 CCOc1ccc(CNC(=O)CSc2nnc(C)c3c(C)n(-c4ccc(Cl)cc4)nc23)cc1 nan
CHEMBL1435835 35215 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 7 4.9 CCOc1ccc(CNC(=O)CSc2nnc(C)c3c(C)n(-c4ccc(Cl)cc4)nc23)cc1 nan
1741544 37631 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccccc1C(=O)Nc1ccc2oc(-c3cccc4c(Br)cccc34)nc2c1 nan
CHEMBL1457270 37631 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccccc1C(=O)Nc1ccc2oc(-c3cccc4c(Br)cccc34)nc2c1 nan
2136370 38117 4 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 3.3 CCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccccc12 nan
CHEMBL1461369 38117 4 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 3.3 CCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccccc12 nan
3594053 39540 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Cl)c1 nan
CHEMBL1473447 39540 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Cl)c1 nan
16241285 40455 2 None 1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 2.3 CN(C)C=O.CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
CHEMBL1482781 40455 2 None 1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 2.3 CN(C)C=O.CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
1241177 41244 12 None -1 3 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 0 8 2.4 c1ccc(COn2nnc3ccccc32)c(COn2nnc3ccccc32)c1 nan
CHEMBL1489236 41244 12 None -1 3 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 0 8 2.4 c1ccc(COn2nnc3ccccc32)c(COn2nnc3ccccc32)c1 nan
16009541 41968 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccc(F)cc4)cc3)cc(=O)n12 nan
CHEMBL1495115 41968 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccc(F)cc4)cc3)cc(=O)n12 nan
2978485 42688 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 2 4.1 CCC(C)NC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
CHEMBL1501669 42688 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 2 4.1 CCC(C)NC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
7514097 42735 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 4 6 2.2 O=C(O)CCNc1ccc(NCCC(=O)O)c2c1C(=O)c1ccccc1C2=O nan
CHEMBL1502018 42735 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 4 6 2.2 O=C(O)CCNc1ccc(NCCC(=O)O)c2c1C(=O)c1ccccc1C2=O nan
5777938 42830 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 10 1 8 4.1 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1502864 42830 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 10 1 8 4.1 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
1256983 43562 14 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 3 5.3 O=C(Nc1ccc(F)cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
CHEMBL1509228 43562 14 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 3 5.3 O=C(Nc1ccc(F)cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
16017574 43895 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 8 1 6 2.5 CCCCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
CHEMBL1512435 43895 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 8 1 6 2.5 CCCCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
15988274 43996 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
CHEMBL1513838 43996 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
4921215 44151 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 2 4 6.7 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)Nc3ccc(C)c(C)c3)sc2n1 nan
CHEMBL1516149 44151 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 2 4 6.7 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)Nc3ccc(C)c(C)c3)sc2n1 nan
135466071 46226 1 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 6 4.5 CCc1cc2c(s1)N1Cc3ccccc3C(C(=O)c3cccc([N+](=O)[O-])c3)=C1NC2=O nan
CHEMBL1535161 46226 1 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 6 4.5 CCc1cc2c(s1)N1Cc3ccccc3C(C(=O)c3cccc([N+](=O)[O-])c3)=C1NC2=O nan
16024942 48229 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.7 CCc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1553067 48229 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.7 CCc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16015892 48243 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(-c2nc3cc(NC(=O)COc4ccc(C)c(C)c4)ccc3o2)cc1 nan
CHEMBL1553238 48243 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(-c2nc3cc(NC(=O)COc4ccc(C)c(C)c4)ccc3o2)cc1 nan
16028168 48912 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(F)c3)cc21 nan
CHEMBL1560108 48912 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(F)c3)cc21 nan
16009056 49366 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 3.7 COC(=O)c1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(C(=O)OC)c1 nan
CHEMBL1564251 49366 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 3.7 COC(=O)c1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(C(=O)OC)c1 nan
626021 50314 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 4 3.0 CNC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
CHEMBL1572204 50314 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 4 3.0 CNC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
2462898 50736 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 0 5 3.4 COc1ccc(C(C)=O)cc1COc1ncnc2ccccc12 nan
CHEMBL1576381 50736 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 0 5 3.4 COc1ccc(C(C)=O)cc1COc1ncnc2ccccc12 nan
16024893 52383 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 4.2 COc1ccc(OC)c(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
CHEMBL1590399 52383 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 4.2 COc1ccc(OC)c(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
16010832 52414 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.0 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3cccnc32)cc1C nan
CHEMBL1590845 52414 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.0 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3cccnc32)cc1C nan
16019294 52498 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 1 8 5.2 Cc1cc(C)cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)c1 nan
CHEMBL1591857 52498 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 1 8 5.2 Cc1cc(C)cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)c1 nan
3854561 52575 16 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 N#Cc1c(C(F)(F)F)cc(-c2ccc(F)cc2)nc1SCC(=O)Nc1ccccc1 nan
CHEMBL1592912 52575 16 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 N#Cc1c(C(F)(F)F)cc(-c2ccc(F)cc2)nc1SCC(=O)Nc1ccccc1 nan
16018208 53478 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
CHEMBL1601478 53478 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
16025642 53630 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 6 1 6 5.9 Cc1cccc(C)c1NC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
CHEMBL1603009 53630 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 6 1 6 5.9 Cc1cccc(C)c1NC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
4402705 54705 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 8 -0.5 CN1C(=O)C(=NNc2cccc(S(=O)(=O)N3CCOCC3)c2)C(=O)N(C)C1=O nan
CHEMBL1611899 54705 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 8 -0.5 CN1C(=O)C(=NNc2cccc(S(=O)(=O)N3CCOCC3)c2)C(=O)N(C)C1=O nan
16018210 54719 3 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 4 5.8 Cc1ccccc1NC(=O)c1oc2c(c1C)-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
CHEMBL1612043 54719 3 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 4 5.8 Cc1ccccc1NC(=O)c1oc2c(c1C)-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
2795741 79851 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 5 5.4 Cc1nc(-c2ccc(S(=O)(=O)Nc3ccc(Br)cc3Cl)s2)cs1 nan
CHEMBL212314 79851 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 5 5.4 Cc1nc(-c2ccc(S(=O)(=O)Nc3ccc(Br)cc3Cl)s2)cs1 nan
3127110 107720 13 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 1 8 2.9 C/C(=N\CCCn1ccnc1)c1c(C)nn(-c2ccc([N+](=O)[O-])cc2)c1O nan
CHEMBL3191381 107720 13 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 1 8 2.9 C/C(=N\CCCn1ccnc1)c1c(C)nn(-c2ccc([N+](=O)[O-])cc2)c1O nan
1528721 108327 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 3.4 CC(=O)/N=c1\scc(-c2ccccc2)n1-c1cccc(O)c1 nan
CHEMBL3198106 108327 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 3.4 CC(=O)/N=c1\scc(-c2ccccc2)n1-c1cccc(O)c1 nan
414 3357 33 None -1445 5 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
93205 3357 33 None -1445 5 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
CHEMBL139000 3357 33 None -1445 5 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
24818570 21171 0 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 3 4 3.8 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)cc1 nan
CHEMBL1312949 21171 0 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 3 4 3.8 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)cc1 nan
3138147 21640 14 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 0 5 5.7 O=C(CSc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1)c1ccccc1 nan
CHEMBL1318270 21640 14 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 0 5 5.7 O=C(CSc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1)c1ccccc1 nan
5428505 23033 27 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 0 1 3 3.3 O=c1oc2cc(O)c(Cl)cc2c2ccccc12 nan
CHEMBL1330383 23033 27 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 0 1 3 3.3 O=c1oc2cc(O)c(Cl)cc2c2ccccc12 nan
5913370 23977 8 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 6 1 5 2.8 COCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1337918 23977 8 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 6 1 5 2.8 COCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
3694202 24325 19 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Cl)c2)no1 nan
CHEMBL1341012 24325 19 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Cl)c2)no1 nan
7190321 24700 13 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 7 2.6 O=C(CSc1ccc2nnc(-c3cccs3)n2n1)N1CCCC1 nan
CHEMBL1344120 24700 13 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 7 2.6 O=C(CSc1ccc2nnc(-c3cccs3)n2n1)N1CCCC1 nan
661441 24746 7 None -2 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1344527 24746 7 None -2 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1530959 24746 7 None -2 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
16017580 25281 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 7 2.9 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Cl)s1 nan
CHEMBL1349094 25281 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 7 2.9 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Cl)s1 nan
3239502 26938 10 None 1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 9 0.3 COc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
CHEMBL1364442 26938 10 None 1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 9 0.3 COc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
7189863 29301 11 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.9 O=C(Nc1nc2cc3c(cc2s1)OCO3)c1ccc(N2C(=O)CCC2=O)cc1 nan
CHEMBL1383330 29301 11 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.9 O=C(Nc1nc2cc3c(cc2s1)OCO3)c1ccc(N2C(=O)CCC2=O)cc1 nan
16189478 29335 2 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 0 6 2.2 CCCCN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1383621 29335 2 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 0 6 2.2 CCCCN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
2457625 30298 1 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 7 -0.0 CN(CC(=O)c1c(N)n(C)c(=O)n(C)c1=O)c1ccccc1 nan
CHEMBL1391543 30298 1 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 7 -0.0 CN(CC(=O)c1c(N)n(C)c(=O)n(C)c1=O)c1ccccc1 nan
686152 30474 41 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1393131 30474 41 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1576064 30474 41 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
16009717 30774 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 Fc1ccc(CNc2nc3c(-c4ccc(F)cc4)nnn3c3ccccc23)cc1 nan
CHEMBL1396454 30774 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 Fc1ccc(CNc2nc3c(-c4ccc(F)cc4)nnn3c3ccccc23)cc1 nan
24892133 30955 8 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 11 1.7 COc1ccccc1-c1nc(SCC(=O)Nc2cc(C)on2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1398694 30955 8 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 11 1.7 COc1ccccc1-c1nc(SCC(=O)Nc2cc(C)on2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
1115170 33148 15 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 5 4.8 Cc1cccc(OCC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)c1 nan
CHEMBL1417596 33148 15 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 5 4.8 Cc1cccc(OCC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)c1 nan
15988646 35347 2 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 4.9 COc1ccccc1NC(=O)c1sc(-c2ccc(Cl)cc2)cc1N nan
CHEMBL1437533 35347 2 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 4.9 COc1ccccc1NC(=O)c1sc(-c2ccc(Cl)cc2)cc1N nan
1341231 35463 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 5 5.5 COc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
CHEMBL1438558 35463 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 5 5.5 COc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
2999623 36560 7 None -1 3 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 9 0 8 2.9 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(CCC(=O)OCc1c(C)noc1C)n2C nan
CHEMBL1448461 36560 7 None -1 3 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 9 0 8 2.9 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(CCC(=O)OCc1c(C)noc1C)n2C nan
2609971 38729 6 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 7 3.2 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccccc2c1=O nan
CHEMBL1466287 38729 6 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 7 3.2 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccccc2c1=O nan
16024828 41637 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5F)CC4)ccc3c2)CC1 nan
CHEMBL1492051 41637 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5F)CC4)ccc3c2)CC1 nan
3276076 42334 9 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 7 3.1 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
CHEMBL1498535 42334 9 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 7 3.1 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
3494087 43778 4 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 7 2.0 Cc1sc2ncnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)c2c1C nan
CHEMBL1511159 43778 4 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 7 2.0 Cc1sc2ncnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)c2c1C nan
22513173 44101 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 7 2.0 COc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccccc4F)ncn3n2)cc1 nan
CHEMBL1515462 44101 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 7 2.0 COc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccccc4F)ncn3n2)cc1 nan
16025349 44641 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.6 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccccc1)S2(=O)=O)Nc1ccccc1 nan
CHEMBL1520822 44641 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.6 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccccc1)S2(=O)=O)Nc1ccccc1 nan
16017252 45895 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.1 Cc1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
CHEMBL1532051 45895 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.1 Cc1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
659886 46201 13 None 1 3 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 5 5.4 CCc1ccccc1NC(=O)CSc1nc2c(c(-c3ccco3)c1C#N)CCCC2 nan
CHEMBL1534846 46201 13 None 1 3 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 5 5.4 CCc1ccccc1NC(=O)CSc1nc2c(c(-c3ccco3)c1C#N)CCCC2 nan
790785 46241 11 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 3 2 3 3.5 CCCc1c(C)nc2ccc(C(=O)O)cc2c1S nan
CHEMBL1535349 46241 11 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 3 2 3 3.5 CCCc1c(C)nc2ccc(C(=O)O)cc2c1S nan
3767937 46682 13 None -3 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 6 5.6 N#Cc1c(N)nc(SCC(=O)C23CC4CC(CC(C4)C2)C3)c(C#N)c1-c1ccc(Cl)cc1 nan
CHEMBL1539280 46682 13 None -3 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 6 5.6 N#Cc1c(N)nc(SCC(=O)C23CC4CC(CC(C4)C2)C3)c(C#N)c1-c1ccc(Cl)cc1 nan
24792845 50356 3 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 1.3 Cc1nn(CC(=O)NCC2CCCO2)c(=O)c2cc3ccccc3n12 nan
CHEMBL1572639 50356 3 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 1.3 Cc1nn(CC(=O)NCC2CCCO2)c(=O)c2cc3ccccc3n12 nan
319257 50374 5 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 4 2 2 3.0 C=C(C)C(=O)Nc1ccc(NC(C)C)cc1 nan
CHEMBL1572793 50374 5 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 4 2 2 3.0 C=C(C)C(=O)Nc1ccc(NC(C)C)cc1 nan
2100389 51668 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 2.5 O=C(COc1ncnc2scc(-c3ccccc3)c12)NCCN1C(=O)CSC1=O nan
CHEMBL1584231 51668 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 2.5 O=C(COc1ncnc2scc(-c3ccccc3)c12)NCCN1C(=O)CSC1=O nan
16019541 52412 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 8 5.1 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(Nc2ccc(C)c(C)c2)c2sccc23)c1 nan
CHEMBL1590799 52412 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 8 5.1 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(Nc2ccc(C)c(C)c2)c2sccc23)c1 nan
16025640 52470 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 5.6 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
CHEMBL1591452 52470 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 5.6 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
1189472 52925 13 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 2.9 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCN1CCOCC1 nan
CHEMBL1596394 52925 13 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 2.9 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCN1CCOCC1 nan
1115820 54669 23 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 6 5.4 COc1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1611566 54669 23 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 6 5.4 COc1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
9581898 72558 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 5 2.0 Cc1cccc(C(=O)N/N=C2\CS(=O)(=O)N(C)c3ccsc32)c1 nan
CHEMBL1992883 72558 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 5 2.0 Cc1cccc(C(=O)N/N=C2\CS(=O)(=O)N(C)c3ccsc32)c1 nan
17584449 109085 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 0 7 2.6 COc1cc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2c2ccccc2)cc(OC)c1OC nan
CHEMBL3213657 109085 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 0 7 2.6 COc1cc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2c2ccccc2)cc(OC)c1OC nan
CHEMBL1411485 208741 0 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL None None None None nan
377 2738 53 None -371 10 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
425 2738 53 None -371 10 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
448222 2738 53 None -371 10 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
CHEMBL464859 2738 53 None -371 10 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
135415429 41276 7 None 2 3 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 8 1 9 4.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(SCc1nc(O)c3sccc3n1)n2CC nan
CHEMBL1489478 41276 7 None 2 3 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 8 1 9 4.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(SCc1nc(O)c3sccc3n1)n2CC nan
6076 107239 67 None 1 2 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
CHEMBL1363683 107239 67 None 1 2 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
CHEMBL316966 107239 67 None 1 2 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
20923189 19762 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 0 6 2.1 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1 nan
CHEMBL1301594 19762 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 0 6 2.1 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1 nan
613860 20181 11 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 6 2.9 Cc1noc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)c1C nan
CHEMBL1305078 20181 11 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 6 2.9 Cc1noc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)c1C nan
2480606 20391 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 2 7 0.6 Cc1cccc(NCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
CHEMBL1306773 20391 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 2 7 0.6 Cc1cccc(NCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
224672 22676 48 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 3 1 3 3.1 O=C(O)CSc1ccnc2cc(Cl)ccc12 nan
CHEMBL1327484 22676 48 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 3 1 3 3.1 O=C(O)CSc1ccnc2cc(Cl)ccc12 nan
2384232 22744 31 None -3 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 4.2 Cc1sc2ncnc(Sc3ccccc3C(=O)O)c2c1C nan
CHEMBL1327902 22744 31 None -3 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 4.2 Cc1sc2ncnc(Sc3ccccc3C(=O)O)c2c1C nan
1442817 23220 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.6 Cc1nnc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)s1 nan
CHEMBL1331799 23220 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.6 Cc1nnc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)s1 nan
6103449 23841 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 0 3 4.0 CCN1/C(=C2\C(=O)N(C)C(=S)N2c2ccccc2)C=Cc2ccccc21 nan
CHEMBL1336606 23841 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 0 3 4.0 CCN1/C(=C2\C(=O)N(C)C(=S)N2c2ccccc2)C=Cc2ccccc21 nan
662886 23874 9 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 7 3.5 Brc1ccc(-c2nn3c(-c4ccco4)nnc3s2)o1 nan
CHEMBL1336927 23874 9 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 7 3.5 Brc1ccc(-c2nn3c(-c4ccco4)nnc3s2)o1 nan
16011044 26664 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)NC(=O)c2ccccc2S3)cc1 nan
CHEMBL1362040 26664 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)NC(=O)c2ccccc2S3)cc1 nan
826482 26786 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 250 1 2 6 1.8 CC1(C)Cc2c(sc3ncnc(NN)c23)CO1 nan
CHEMBL1363060 26786 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 250 1 2 6 1.8 CC1(C)Cc2c(sc3ncnc(NN)c23)CO1 nan
16024887 27194 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 4.6 CCOc1ccccc1CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1366554 27194 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 4.6 CCOc1ccccc1CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
3207679 29122 4 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1cccc2cc(C#N)c(SCC(=O)NCc3cccs3)nc12 nan
CHEMBL1381650 29122 4 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1cccc2cc(C#N)c(SCC(=O)NCc3cccs3)nc12 nan
2445448 29613 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 0 7 1.4 COc1ccc(C(C)=O)cc1Cn1cnc2c(cnn2C)c1=O nan
CHEMBL1386075 29613 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 0 7 1.4 COc1ccc(C(C)=O)cc1Cn1cnc2c(cnn2C)c1=O nan
15988012 29972 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1388847 29972 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
2917979 30052 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 9 4.0 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)nc1C nan
CHEMBL1389475 30052 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 9 4.0 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)nc1C nan
686152 30474 41 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1393131 30474 41 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1576064 30474 41 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
15987889 33184 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 8 1 4 5.4 CCN(CC)CC(C)CNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1417926 33184 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 8 1 4 5.4 CCN(CC)CC(C)CNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
20904552 33782 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 8 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
CHEMBL1422972 33782 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 8 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
2375468 34903 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 -0.2 Cn1c(N)c(C(=O)COc2ccc(C#N)cc2)c(=O)n(C)c1=O nan
CHEMBL1432350 34903 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 -0.2 Cn1c(N)c(C(=O)COc2ccc(C#N)cc2)c(=O)n(C)c1=O nan
16024881 35048 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 4 2.6 CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1433473 35048 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 4 2.6 CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
15991045 35057 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 3 1 3 7.0 Cc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
CHEMBL1433636 35057 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 3 1 3 7.0 Cc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
16015278 35144 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 6 5.3 CC(=O)c1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4)c3C)nc2C)cc1 nan
CHEMBL1434956 35144 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 6 5.3 CC(=O)c1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4)c3C)nc2C)cc1 nan
5078950 35503 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1438931 35503 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
5310383 35938 11 None -1 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 0.3 O=C(Cn1cnc2c(nnn2-c2ccccc2)c1=O)NCC1CCCO1 nan
CHEMBL1442757 35938 11 None -1 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 0.3 O=C(Cn1cnc2c(nnn2-c2ccccc2)c1=O)NCC1CCCO1 nan
948433 35951 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 1 4 3.7 COc1ccc(CNC(=O)CSc2cccc3cccnc23)cc1 nan
CHEMBL1442938 35951 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 1 4 3.7 COc1ccc(CNC(=O)CSc2cccc3cccnc23)cc1 nan
16019658 36212 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 7 3.2 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1C nan
CHEMBL1445403 36212 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 7 3.2 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1C nan
3208298 38796 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 3.7 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1nccs1)OCO3 nan
CHEMBL1466770 38796 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 3.7 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1nccs1)OCO3 nan
6623284 39449 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 0 7 3.0 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCCC2)s1 nan
CHEMBL1472373 39449 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 0 7 3.0 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCCC2)s1 nan
5302642 39578 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 2 4 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2)cc1 nan
CHEMBL1474011 39578 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 2 4 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2)cc1 nan
1203028 39603 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 2 8 0.0 CC(=O)Nc1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1474423 39603 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 2 8 0.0 CC(=O)Nc1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
15988309 39936 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 8 2.1 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
CHEMBL1478365 39936 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 8 2.1 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
1387364 40773 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1485560 40773 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1576237 40773 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
4238273 40827 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 6 2.9 Cn1c(SCC(=O)c2ccc3c(c2)NC(=O)CO3)nc2ccccc21 nan
CHEMBL1485997 40827 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 6 2.9 Cn1c(SCC(=O)c2ccc3c(c2)NC(=O)CO3)nc2ccccc21 nan
16025632 41726 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
CHEMBL1492743 41726 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
1252362 42497 15 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 5 5.2 COc1ccc(-n2c(-c3cccc(OC)c3)nc(=S)c3c2CCCC3)cc1 nan
CHEMBL1499911 42497 15 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 5 5.2 COc1ccc(-n2c(-c3cccc(OC)c3)nc(=S)c3c2CCCC3)cc1 nan
3173852 42589 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 4 3.8 CNC(=S)N(Cc1ccc(OC)cc1)Cc1cc2cc(C)ccc2nc1O nan
CHEMBL1500673 42589 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 4 3.8 CNC(=S)N(Cc1ccc(OC)cc1)Cc1cc2cc(C)ccc2nc1O nan
16189472 43225 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 2.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)Nc1cccnc1Cl)C(=O)CO2 nan
CHEMBL1506287 43225 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 2.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)Nc1cccnc1Cl)C(=O)CO2 nan
20953562 43563 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 7 2.9 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)ncn3n2)cc1 nan
CHEMBL1509249 43563 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 7 2.9 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)ncn3n2)cc1 nan
20923188 43730 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 6 2.4 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccccc1 nan
CHEMBL1510719 43730 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 6 2.4 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccccc1 nan
16025766 44005 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 4 5.8 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccccc3Cl)CC2)s1 nan
CHEMBL1514065 44005 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 4 5.8 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccccc3Cl)CC2)s1 nan
5206706 44015 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.8 CN(C)c1ccc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)cc1 nan
CHEMBL1514233 44015 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.8 CN(C)c1ccc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)cc1 nan
15988349 44132 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccc(F)cc3)c2n1 nan
CHEMBL1515965 44132 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccc(F)cc3)c2n1 nan
4458977 44358 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 11 0.7 CCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1518407 44358 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 11 0.7 CCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
15989681 44456 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 7 1 7 4.1 COc1cc2c(=O)n(Cc3ccccc3Cl)c(=O)n(CC(=O)Nc3ccc(C)c(C)c3)c2cc1OC nan
CHEMBL1519224 44456 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 7 1 7 4.1 COc1cc2c(=O)n(Cc3ccccc3Cl)c(=O)n(CC(=O)Nc3ccc(C)c(C)c3)c2cc1OC nan
16019398 45168 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 0 9 2.6 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Cl)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1525727 45168 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 0 9 2.6 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Cl)cc4)nnn3c3ccsc23)CC1 nan
16009804 45518 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 7 4.3 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1C nan
CHEMBL1528709 45518 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 7 4.3 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1C nan
2808993 45632 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 0 5 3.4 CCc1nc2ccccc2nc1N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 nan
CHEMBL1529717 45632 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 0 5 3.4 CCc1nc2ccccc2nc1N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 nan
588806 46439 23 None -1 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 4 1 4 2.5 Cc1nc(SCCC(=O)O)c2ccccc2n1 nan
CHEMBL1537195 46439 23 None -1 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 4 1 4 2.5 Cc1nc(SCCC(=O)O)c2ccccc2n1 nan
2810142 47155 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 5 3.6 O=C(Nc1nc2ccsc2c(=O)s1)c1ccc(Cl)cc1 nan
CHEMBL1543276 47155 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 5 3.6 O=C(Nc1nc2ccsc2c(=O)s1)c1ccc(Cl)cc1 nan
2158355 47576 7 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 7 0 7 1.6 COCCN(CCOC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1546597 47576 7 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 7 0 7 1.6 COCCN(CCOC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
1304353 48255 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 3 5.4 Cc1ccc(-c2sc(C(=O)Nc3ccc(Br)cc3)cc2CC(=O)O)cc1 nan
CHEMBL1553391 48255 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 3 5.4 Cc1ccc(-c2sc(C(=O)Nc3ccc(Br)cc3)cc2CC(=O)O)cc1 nan
3725217 48666 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 2 2 6 2.1 CC(C)C1Cc2c(sc3ncnc(NN)c23)CO1 nan
CHEMBL1557963 48666 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 2 2 6 2.1 CC(C)C1Cc2c(sc3ncnc(NN)c23)CO1 nan
16017731 49450 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 5 1.5 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)NCCc1ccccc1 nan
CHEMBL1565042 49450 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 5 1.5 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)NCCc1ccccc1 nan
7184630 51555 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1ccccc1CNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1583340 51555 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1ccccc1CNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
24856176 52118 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 4 3.3 CN(CC(=O)Nc1ccccc1Cl)C(=O)COC(=O)Cc1c(F)cccc1Cl nan
CHEMBL1587934 52118 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 4 3.3 CN(CC(=O)Nc1ccccc1Cl)C(=O)COC(=O)Cc1c(F)cccc1Cl nan
16033298 52378 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 5.5 Cc1c(C(=O)NCc2ccc(OC(C)C)cc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1590310 52378 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 5.5 Cc1c(C(=O)NCc2ccc(OC(C)C)cc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
16010771 52542 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 6 3.5 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(Cc2ccccc2Cl)c(=O)c2cccnc21 nan
CHEMBL1592455 52542 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 6 3.5 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(Cc2ccccc2Cl)c(=O)c2cccnc21 nan
16029563 52668 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 6 4.2 COc1ccc(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(C)ccc32)cc1Cl nan
CHEMBL1594200 52668 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 6 4.2 COc1ccc(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(C)ccc32)cc1Cl nan
18553656 52860 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 9 1.0 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(CC(C)(C)C)nc2n(C)c1=O nan
CHEMBL1595812 52860 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 9 1.0 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(CC(C)(C)C)nc2n(C)c1=O nan
773677 53492 29 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 1 1 4 3.9 Cc1ccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCC4)cc1 nan
CHEMBL1601668 53492 29 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 1 1 4 3.9 Cc1ccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCC4)cc1 nan
1414561 53862 31 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 5 4.0 C=CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1604975 53862 31 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 5 4.0 C=CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
135693221 54950 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1359119 54950 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1615929 54950 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
6476987 55317 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL1385494 55317 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL1618897 55317 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
135502886 121650 24 None -2 4 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 221 1 2 4 1.1 NC(=S)c1cc2ccc(O)cc2oc1=O nan
CHEMBL358644 121650 24 None -2 4 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 221 1 2 4 1.1 NC(=S)c1cc2ccc(O)cc2oc1=O nan
24360 203321 106 None -12 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 6 2.1 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
CHEMBL65 203321 106 None -12 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 6 2.1 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
5359 207686 75 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 4 1 3 3.2 CC(C(=O)O)c1ccc(C(=O)c2cccs2)cc1 nan
CHEMBL956 207686 75 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 4 1 3 3.2 CC(C(=O)O)c1ccc(C(=O)c2cccs2)cc1 nan
2647611 52622 13 None - 1 Human 3.9 pPotency = 3.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 6 3.0 CC(=O)c1c(C)[nH]c(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)c1C nan
CHEMBL1593590 52622 13 None - 1 Human 3.9 pPotency = 3.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 6 3.0 CC(=O)c1c(C)[nH]c(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)c1C nan
126054 43907 40 None - 1 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 11 7 12 -0.0 NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4c3ncn4[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1 nan
CHEMBL1512545 43907 40 None - 1 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 11 7 12 -0.0 NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4c3ncn4[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1 nan
380 1276 54 None -7413 5 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
657378 1276 54 None -7413 5 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
CHEMBL68738 1276 54 None -7413 5 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
191 13142 59 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 9 -2.0 Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
CHEMBL11909 13142 59 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 9 -2.0 Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
15988009 19679 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1300978 19679 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
1246444 19726 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 2 8 2.6 COc1cc(OC)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)cc1OC nan
CHEMBL1301318 19726 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 2 8 2.6 COc1cc(OC)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)cc1OC nan
5733367 19764 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 9 1 6 3.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C2c2ccc(F)cc2)cc1C nan
CHEMBL1301612 19764 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 9 1 6 3.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C2c2ccc(F)cc2)cc1C nan
3207945 19804 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 5 2.9 CCOC(=O)CNC(=O)CSc1nc2c(C)cccc2cc1CC nan
CHEMBL1302034 19804 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 5 2.9 CCOC(=O)CNC(=O)CSc1nc2c(C)cccc2cc1CC nan
2978035 20030 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 4 1.3 O=C(CN1C(=O)c2ccc(Br)cc2C1=O)NCC1CCCO1 nan
CHEMBL1303768 20030 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 4 1.3 O=C(CN1C(=O)c2ccc(Br)cc2C1=O)NCC1CCCO1 nan
16194904 21195 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)CC1 nan
CHEMBL1313100 21195 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)CC1 nan
127136 21310 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549067 21310 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549068 21310 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549069 21310 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
CHEMBL1314043 21310 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
CHEMBL1556805 21310 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
3151367 21347 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 1.8 CCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
CHEMBL1314339 21347 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 1.8 CCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
16009645 21433 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 2 5 5.9 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)cc1OCC nan
CHEMBL1315511 21433 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 2 5 5.9 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)cc1OCC nan
16009682 21474 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1cccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)c1 nan
CHEMBL1315996 21474 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1cccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)c1 nan
16023134 21598 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 6 2.4 CNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)C1 nan
CHEMBL1317674 21598 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 6 2.4 CNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)C1 nan
16019581 21633 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 3 0 9 2.7 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1318189 21633 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 3 0 9 2.7 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
16017720 21643 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 0 4 3.1 O=c1c(=O)n(-c2ccccc2)ccn1Cc1cccc(C(F)(F)F)c1 nan
CHEMBL1318320 21643 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 0 4 3.1 O=c1c(=O)n(-c2ccccc2)ccn1Cc1cccc(C(F)(F)F)c1 nan
2458272 21666 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3ccc4c(c3)OCCO4)nc2n1 nan
CHEMBL1318506 21666 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3ccc4c(c3)OCCO4)nc2n1 nan
15988341 21699 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 2 5 5.3 COc1ccc(-c2cc(C(=O)NCCc3ccccc3)c3c(-c4ccccc4)[nH]nc3n2)cc1OC nan
CHEMBL1318769 21699 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 2 5 5.3 COc1ccc(-c2cc(C(=O)NCCc3ccccc3)c3c(-c4ccccc4)[nH]nc3n2)cc1OC nan
3245692 21711 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.3 c1ccc(CCNc2nc3ccccc3n3nnnc23)cc1 nan
CHEMBL1318873 21711 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.3 c1ccc(CCNc2nc3ccccc3n3nnnc23)cc1 nan
16009520 22090 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3ccc(NC(=O)c4ccccc4F)cc3)cc(=O)n12 nan
CHEMBL1322132 22090 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3ccc(NC(=O)c4ccccc4F)cc3)cc(=O)n12 nan
1003845 22122 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)c(F)c4)sc3n2)c1 nan
CHEMBL1322400 22122 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)c(F)c4)sc3n2)c1 nan
1021427 22627 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 2 4 4.5 Cn1nc(C(=O)Nc2ccc(Br)cc2)cc1C(=O)Nc1ccc(Br)cc1 nan
CHEMBL1327019 22627 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 2 4 4.5 Cn1nc(C(=O)Nc2ccc(Br)cc2)cc1C(=O)Nc1ccc(Br)cc1 nan
1386649 23433 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
1386650 23433 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
CHEMBL1333441 23433 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
24503354 23579 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 3 2.5 O=C(c1ccc(S(=O)(=O)Nc2ccccc2F)cc1)N1CCC1 nan
CHEMBL1334480 23579 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 3 2.5 O=C(c1ccc(S(=O)(=O)Nc2ccccc2F)cc1)N1CCC1 nan
15988003 23669 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)c(F)c3)nnc12 nan
CHEMBL1335235 23669 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)c(F)c3)nnc12 nan
135416637 24056 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 2 7 5.8 Cc1ccc(C)c(NC(=O)CSc2nc(O)c3c(C(F)(F)F)cc(-c4cccs4)nc3n2)c1 nan
CHEMBL1338446 24056 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 2 7 5.8 Cc1ccc(C)c(NC(=O)CSc2nc(O)c3c(C(F)(F)F)cc(-c4cccs4)nc3n2)c1 nan
1023823 24299 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 4 3.3 NS(=O)(=O)c1c(Sc2ccccc2C(=O)O)ccc2ccccc12 nan
CHEMBL1340736 24299 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 4 3.3 NS(=O)(=O)c1c(Sc2ccccc2C(=O)O)ccc2ccccc12 nan
3420063 24450 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 2 7 3.4 COc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)c(OC)c1 nan
CHEMBL1342030 24450 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 2 7 3.4 COc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)c(OC)c1 nan
2023917 25026 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 3 4 4.5 O=C(NC(=S)Nc1ccccc1C(=O)O)c1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1346887 25026 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 3 4 4.5 O=C(NC(=S)Nc1ccccc1C(=O)O)c1ccc(-c2ccc(Br)cc2)o1 nan
6145649 25116 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 7 1 6 2.9 N#Cc1nc(/C=C/c2ccccc2)oc1NCCCN1CCOCC1 nan
CHEMBL1347564 25116 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 7 1 6 2.9 N#Cc1nc(/C=C/c2ccccc2)oc1NCCCN1CCOCC1 nan
3099832 25175 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 3.7 Cc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)cc1 nan
CHEMBL1348101 25175 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 3.7 Cc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)cc1 nan
16033268 26024 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1cccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
CHEMBL1355268 26024 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1cccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
16004219 26083 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 7 4.6 Brc1ccc(-c2ccc(CNCCSc3nnnn3-c3ccccc3)o2)cc1 nan
CHEMBL1356105 26083 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 7 4.6 Brc1ccc(-c2ccc(CNCCSc3nnnn3-c3ccccc3)o2)cc1 nan
16033294 26095 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 6 5.1 CCOc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1356206 26095 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 6 5.1 CCOc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
16018776 26158 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 6 4.8 Cc1cc2c(cc3c(SCC(=O)Nc4cccc(Cl)c4C)nnc(C)n32)o1 nan
CHEMBL1357046 26158 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 6 4.8 Cc1cc2c(cc3c(SCC(=O)Nc4cccc(Cl)c4C)nnc(C)n32)o1 nan
16014983 26289 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2cccc(C)c2)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1358814 26289 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2cccc(C)c2)c(C#N)c(-c2ccccc2)n1 nan
7190674 26659 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1F nan
CHEMBL1361981 26659 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1F nan
2138626 26743 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1ccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)cc1 nan
CHEMBL1362650 26743 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1ccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)cc1 nan
4152428 26998 7 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
CHEMBL1364957 26998 7 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
15988005 27155 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 2.6 Cc1ccc(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1366276 27155 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 2.6 Cc1ccc(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
15996111 27247 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 4 4.9 CCOCCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1367087 27247 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 4 4.9 CCOCCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
659844 27333 14 None -11 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 8 3.9 CCCCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OCC)cc2)c1C#N nan
CHEMBL1367765 27333 14 None -11 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 8 3.9 CCCCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OCC)cc2)c1C#N nan
5287091 27361 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 2 4.7 Cc1ccc2nc(/C(C#N)=C/c3cccc(Br)c3)[nH]c2c1 nan
CHEMBL1367954 27361 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 2 4.7 Cc1ccc2nc(/C(C#N)=C/c3cccc(Br)c3)[nH]c2c1 nan
15991106 27391 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 1 5 6.0 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1C nan
CHEMBL1368193 27391 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 1 5 6.0 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1C nan
3544515 27421 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 6 1 9 2.2 O=C(O)CCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
CHEMBL1368416 27421 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 6 1 9 2.2 O=C(O)CCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
4191572 27490 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 COc1ccccc1Cn1c(=S)[nH]c2ccc(F)cc2c1=O nan
CHEMBL1368980 27490 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 COc1ccccc1Cn1c(=S)[nH]c2ccc(F)cc2c1=O nan
2743471 28432 22 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 2 1 4 3.7 CSc1cc(-c2ccc(Cl)cc2)nc(O)c1C#N nan
CHEMBL1375507 28432 22 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 2 1 4 3.7 CSc1cc(-c2ccc(Cl)cc2)nc(O)c1C#N nan
1175821 28436 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 0 10 0.7 CC(C)n1c(SCC(=O)N2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1375543 28436 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 0 10 0.7 CC(C)n1c(SCC(=O)N2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
3241220 28474 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 1.4 O=C(Cn1cnc2c(oc3ccccc32)c1=O)NCC1CCCO1 nan
CHEMBL1375857 28474 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 1.4 O=C(Cn1cnc2c(oc3ccccc32)c1=O)NCC1CCCO1 nan
5733045 28731 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 5 4.5 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2cccc(Cl)c2)cc1 nan
CHEMBL1378340 28731 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 5 4.5 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2cccc(Cl)c2)cc1 nan
3746307 29254 28 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 1 1 5 3.4 Cn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1382865 29254 28 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 1 1 5 3.4 Cn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
2939274 29313 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 7 4.5 CC(C)c1nnc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)s1 nan
CHEMBL1383461 29313 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 7 4.5 CC(C)c1nnc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)s1 nan
16194976 29386 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)CC1 nan
CHEMBL1384046 29386 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)CC1 nan
15987888 29429 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1384448 29429 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
2944910 29504 10 None -3 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 6 4.2 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccnc1)c1cc2ccccc2o1 nan
CHEMBL1385074 29504 10 None -3 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 6 4.2 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccnc1)c1cc2ccccc2o1 nan
1928929 29756 12 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 3 2 7 5.5 Nc1c(C(=O)Nc2nc3ccccc3s2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1387110 29756 12 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 3 2 7 5.5 Nc1c(C(=O)Nc2nc3ccccc3s2)sc2nc(-c3cccs3)ccc12 nan
2237376 29778 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 2 8 3.0 CSc1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
CHEMBL1387290 29778 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 2 8 3.0 CSc1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
2779879 30162 30 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 3 4.1 Cc1c(C(=O)c2ccccc2C(=O)O)sc2ccccc12 nan
CHEMBL1390399 30162 30 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 3 4.1 Cc1c(C(=O)c2ccccc2C(=O)O)sc2ccccc12 nan
5088202 30660 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cccc(C)c4)sc3n2)cc1 nan
CHEMBL1394959 30660 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cccc(C)c4)sc3n2)cc1 nan
16018778 30755 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4ccc(Cl)cc4)nnc(C)n32)o1 nan
CHEMBL1396136 30755 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4ccc(Cl)cc4)nnc(C)n32)o1 nan
15987656 30819 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 12 1 6 5.8 CCOc1ccc(CCNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1OCC nan
CHEMBL1397047 30819 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 12 1 6 5.8 CCOc1ccc(CCNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1OCC nan
16018052 30841 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 4 3.8 Cc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1397347 30841 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 4 3.8 Cc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
15987604 30860 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1ccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)cc1 nan
CHEMBL1397611 30860 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1ccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)cc1 nan
866239 30913 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 2.9 Cc1ccc(-n2c(=O)[nH]c3sc4c(c3c2=O)CCCC4)cc1 nan
CHEMBL1398397 30913 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 2.9 Cc1ccc(-n2c(=O)[nH]c3sc4c(c3c2=O)CCCC4)cc1 nan
15990870 31070 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 3 5.3 Cc1ccc(C)c(Nc2cc(C(=O)NC3CCCC3)c3ccccc3n2)c1 nan
CHEMBL1399859 31070 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 3 5.3 Cc1ccc(C)c(Nc2cc(C(=O)NC3CCCC3)c3ccccc3n2)c1 nan
20904142 31173 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 0 9 1.3 COc1ccc(N2CCN(C(=O)CCc3nnc4ccc(N5CCOCC5)nn34)CC2)cc1 nan
CHEMBL1400806 31173 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 0 9 1.3 COc1ccc(N2CCN(C(=O)CCc3nnc4ccc(N5CCOCC5)nn34)CC2)cc1 nan
2859630 31977 19 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 0.9 O=C(CN1C(=O)c2cccc3cccc(c23)C1=O)NCCN1CCOCC1 nan
CHEMBL1408014 31977 19 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 0.9 O=C(CN1C(=O)c2cccc3cccc(c23)C1=O)NCCN1CCOCC1 nan
22553366 32026 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 7 1.5 CCOC(=O)C1CCN(C(=O)Cn2c(=O)c3cccn3c3cccnc32)CC1 nan
CHEMBL1408318 32026 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 7 1.5 CCOC(=O)C1CCN(C(=O)Cn2c(=O)c3cccn3c3cccnc32)CC1 nan
2911470 32701 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 8 3.8 C=CCOc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1413736 32701 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 8 3.8 C=CCOc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
663378 32726 8 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 3 0 5 3.4 N#CCCSc1ncnc2c1oc1ccccc12 nan
CHEMBL1413946 32726 8 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 3 0 5 3.4 N#CCCSc1ncnc2c1oc1ccccc12 nan
1175547 32811 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 9 2.6 COc1cc(OC)cc(-n2nnnc2SCC(=O)Nc2ccc(C(C)=O)cc2)c1 nan
CHEMBL1414657 32811 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 9 2.6 COc1cc(OC)cc(-n2nnnc2SCC(=O)Nc2ccc(C(C)=O)cc2)c1 nan
2152512 32835 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1ccccc1OC nan
CHEMBL1414820 32835 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1ccccc1OC nan
16033750 32961 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 3 5.8 CC(C)c1ccc(N2C(=O)N(Cc3ccccc3Cl)c3ccccc3S2(=O)=O)cc1 nan
CHEMBL1416012 32961 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 3 5.8 CC(C)c1ccc(N2C(=O)N(Cc3ccccc3Cl)c3ccccc3S2(=O)=O)cc1 nan
1138440 33000 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 10 1.8 CCCn1c(SCC(=O)c2ccc(OC)c(OC)c2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1416338 33000 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 10 1.8 CCCn1c(SCC(=O)c2ccc(OC)c(OC)c2)nc2c1c(=O)n(C)c(=O)n2C nan
135445597 33089 22 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 2 1 6 2.5 CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1417116 33089 22 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 2 1 6 2.5 CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
24892379 33249 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 9 1.7 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3Cl)nc2n(C)c1=O nan
CHEMBL1418535 33249 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 9 1.7 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3Cl)nc2n(C)c1=O nan
24789790 33295 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 0 8 0.8 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3scc(C)n3c2=O)CC1 nan
CHEMBL1418824 33295 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 0 8 0.8 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3scc(C)n3c2=O)CC1 nan
5220580 33394 15 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 5 4.0 CC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2Cl)nc1C nan
CHEMBL1419730 33394 15 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 5 4.0 CC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2Cl)nc1C nan
3699048 33399 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 2 6 3.5 Cc1ccc[n+](C2C(c3cccs3)C(C#N)=C([C-](C#N)C#N)NC2(O)c2ccccc2)c1 nan
CHEMBL1419826 33399 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 2 6 3.5 Cc1ccc[n+](C2C(c3cccs3)C(C#N)=C([C-](C#N)C#N)NC2(O)c2ccccc2)c1 nan
5790281 33532 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 10 1 7 3.7 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1 nan
CHEMBL1420847 33532 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 10 1 7 3.7 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1 nan
2974740 33540 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 4 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3cccs3)nc12 nan
CHEMBL1420938 33540 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 4 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3cccs3)nc12 nan
824727 33572 12 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 2 0 4 2.2 CCOC(=O)c1cc(Br)c(=O)n2ccccc12 nan
CHEMBL1421240 33572 12 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 2 0 4 2.2 CCOC(=O)c1cc(Br)c(=O)n2ccccc12 nan
6411582 33677 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 10 2 10 4.3 CCOC(=O)CCCCC(=O)c1[nH]c(O)nc1CSc1nnc2c3cc(Br)ccc3n(C)c2n1 nan
CHEMBL1422131 33677 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 10 2 10 4.3 CCOC(=O)CCCCC(=O)c1[nH]c(O)nc1CSc1nnc2c3cc(Br)ccc3n(C)c2n1 nan
4910054 33722 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 9 1.1 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(CCO)CC4)o3)nnc2c2ccccc12 nan
CHEMBL1422462 33722 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 9 1.1 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(CCO)CC4)o3)nnc2c2ccccc12 nan
2945586 33853 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.6 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1ccncc1)c1cc2ccccc2o1 nan
CHEMBL1423531 33853 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.6 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1ccncc1)c1cc2ccccc2o1 nan
614539 33890 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Br)cc2c1OCC2 nan
CHEMBL1423802 33890 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Br)cc2c1OCC2 nan
5928009 34209 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 9 -0.1 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CCC(C(N)=O)CC3)nc12 nan
CHEMBL1426470 34209 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 9 -0.1 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CCC(C(N)=O)CC3)nc12 nan
20957179 34305 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 9 0.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
CHEMBL1427296 34305 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 9 0.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
2376694 34310 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 8 0.5 Cn1c(N)c(C(=O)CSc2nc3ccccc3[nH]2)c(=O)n(C)c1=O nan
CHEMBL1427343 34310 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 8 0.5 Cn1c(N)c(C(=O)CSc2nc3ccccc3[nH]2)c(=O)n(C)c1=O nan
20970067 34535 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 9 1 8 2.4 COc1ccc(OC)c(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)c1 nan
CHEMBL1429318 34535 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 9 1 8 2.4 COc1ccc(OC)c(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)c1 nan
2950264 34554 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 6 2.6 O=C(CSc1ncnc2sc3c(c12)CCC3)NCC1CCCO1 nan
CHEMBL1429474 34554 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 6 2.6 O=C(CSc1ncnc2sc3c(c12)CCC3)NCC1CCCO1 nan
135436945 35052 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 2 4 5.5 Cc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c(C)c1 nan
CHEMBL1433539 35052 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 2 4 5.5 Cc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c(C)c1 nan
16030485 35153 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1435046 35153 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
1775325 35212 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 0 6 4.3 COc1ccc(CN2COc3ccc4c(oc(=O)c5ccccc54)c3C2)cc1OC nan
CHEMBL1435817 35212 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 0 6 4.3 COc1ccc(CN2COc3ccc4c(oc(=O)c5ccccc54)c3C2)cc1OC nan
135433305 35717 1 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 3 8 1.3 CNC(=O)NC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1440872 35717 1 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 3 8 1.3 CNC(=O)NC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
2816654 36358 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 1 6 1.9 CCOC(=O)N1CCc2c(sc3ncnc(O)c23)C1 nan
CHEMBL1446784 36358 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 1 6 1.9 CCOC(=O)N1CCc2c(sc3ncnc(O)c23)C1 nan
749058 36422 28 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 5 4.8 O=c1c2c(-c3cccs3)csc2[nH]c(=S)n1-c1ccccc1 nan
CHEMBL1447245 36422 28 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 5 4.8 O=c1c2c(-c3cccs3)csc2[nH]c(=S)n1-c1ccccc1 nan
739884 36516 81 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 1 1 2 3.9 O=C(O)c1sc2cc(Cl)ccc2c1Cl nan
CHEMBL1448105 36516 81 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 1 1 2 3.9 O=C(O)c1sc2cc(Cl)ccc2c1Cl nan
16033236 36697 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2ccccc2Cl)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1449453 36697 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2ccccc2Cl)sc2ncnc(N(C)C3CCCCC3)c12 nan
2572725 36859 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 6 2.8 Cc1cc(C(=O)OCC(=O)c2ccc(Br)s2)no1 nan
CHEMBL1450791 36859 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 6 2.8 Cc1cc(C(=O)OCC(=O)c2ccc(Br)s2)no1 nan
2787753 37078 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 4 3 8 0.6 CC(C)OC(=O)C(C)Nc1nnc(S)nc1O nan
CHEMBL1452524 37078 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 4 3 8 0.6 CC(C)OC(=O)C(C)Nc1nnc(S)nc1O nan
4984225 37557 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.8 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)Nc2cccnc2Cl)cc1 nan
CHEMBL1456558 37557 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.8 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)Nc2cccnc2Cl)cc1 nan
764734 37929 28 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 5 3.6 C=CCn1c(=S)[nH]c2scc(-c3ccco3)c2c1=O nan
CHEMBL1459809 37929 28 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 5 3.6 C=CCn1c(=S)[nH]c2scc(-c3ccco3)c2c1=O nan
2822524 38029 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 5 3.5 CCOC(=O)c1c(SC)nc2c(Cl)cccc2c1O nan
CHEMBL1460605 38029 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 5 3.5 CCOC(=O)c1c(SC)nc2c(Cl)cccc2c1O nan
2973900 38351 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 3 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3ccccc3)nc12 nan
CHEMBL1463377 38351 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 3 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3ccccc3)nc12 nan
5637963 38431 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 0 5 3.7 CCOC(=O)/C(C#N)=C/c1cc2ccccc2nc1N1CCCCC1 nan
CHEMBL1464025 38431 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 0 5 3.7 CCOC(=O)/C(C#N)=C/c1cc2ccccc2nc1N1CCCCC1 nan
1005162 38475 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.9 N#Cc1ccc(-c2ccc(F)cc2)nc1SCC(=O)Nc1sc2c(c1C#N)CCC2 nan
CHEMBL1464360 38475 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.9 N#Cc1ccc(-c2ccc(F)cc2)nc1SCC(=O)Nc1sc2c(c1C#N)CCC2 nan
2087618 38489 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 6 2.8 CCOc1cc(C=O)ccc1OCc1cc(=O)n2cc(C)ccc2n1 nan
CHEMBL1464466 38489 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 6 2.8 CCOc1cc(C=O)ccc1OCc1cc(=O)n2cc(C)ccc2n1 nan
20904553 38700 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.8 CC(NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12)c1ccccc1 nan
CHEMBL1466036 38700 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.8 CC(NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12)c1ccccc1 nan
20923124 38702 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
CHEMBL1466048 38702 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
16681736 38870 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 2 5 3.1 C1COCCO1.O=C(Nc1cccc2ccccc12)C(=O)C1C(=O)Nc2ccccc21 nan
CHEMBL1467358 38870 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 2 5 3.1 C1COCCO1.O=C(Nc1cccc2ccccc12)C(=O)C1C(=O)Nc2ccccc21 nan
2788467 38912 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 2 6 3.4 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
CHEMBL1467713 38912 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 2 6 3.4 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
4224805 38940 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 2.0 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCCCC3)c(=O)c2c1C nan
CHEMBL1468056 38940 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 2.0 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCCCC3)c(=O)c2c1C nan
22334123 39088 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1OC nan
CHEMBL1469191 39088 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1OC nan
5016620 39544 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 5 3.5 COc1ccc(-c2cc(C(=O)Nc3ccc(C#N)cc3)no2)cc1 nan
CHEMBL1473482 39544 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 5 3.5 COc1ccc(-c2cc(C(=O)Nc3ccc(C#N)cc3)no2)cc1 nan
775363 39685 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 7 0.7 Cc1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C nan
CHEMBL1475499 39685 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 7 0.7 Cc1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C nan
16009659 39744 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 7 4.1 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1476377 39744 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 7 4.1 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
5730013 39793 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 4.0 CCC(Sc1nnc2c(n1)[nH]c1ccccc12)C(=O)Nc1nnc(C(C)C)s1 nan
CHEMBL1476964 39793 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 4.0 CCC(Sc1nnc2c(n1)[nH]c1ccccc12)C(=O)Nc1nnc(C(C)C)s1 nan
1782877 39853 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 2 6 3.9 COc1ccc(-c2cc3ccc(OCC(=O)NCC4CCC(C(=O)O)CC4)cc3oc2=O)cc1 nan
CHEMBL1477517 39853 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 2 6 3.9 COc1ccc(-c2cc3ccc(OCC(=O)NCC4CCC(C(=O)O)CC4)cc3oc2=O)cc1 nan
20957466 40105 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 7 1.7 CC1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
CHEMBL1479770 40105 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 7 1.7 CC1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
5378436 40107 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 6 1.4 Cn1c(=O)[nH]c2nnc(-c3ccc(Cl)c(Cl)c3)nc2c1=O nan
CHEMBL1479779 40107 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 6 1.4 Cn1c(=O)[nH]c2nnc(-c3ccc(Cl)c(Cl)c3)nc2c1=O nan
7207545 40915 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)cc3F)nn2)s1 nan
CHEMBL1486756 40915 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)cc3F)nn2)s1 nan
974443 41135 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 7 0.5 COc1cccc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1488414 41135 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 7 0.5 COc1cccc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
250222 41174 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 1 3 2.9 O=C1c2ccccc2C(O)(c2ccccc2)N1c1ccncc1 nan
CHEMBL1488698 41174 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 1 3 2.9 O=C1c2ccccc2C(O)(c2ccccc2)N1c1ccncc1 nan
2158358 41224 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 2 0 7 1.8 CCOC(=O)N1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1489076 41224 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 2 0 7 1.8 CCOC(=O)N1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
4000951 41358 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 11 1.8 Cn1c(N)c(C(=O)CSc2nn(-c3ccc(F)cc3)c(=S)s2)c(=O)n(C)c1=O nan
CHEMBL1490219 41358 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 11 1.8 Cn1c(N)c(C(=O)CSc2nn(-c3ccc(F)cc3)c(=S)s2)c(=O)n(C)c1=O nan
5310114 41418 3 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 7 2.1 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)O nan
CHEMBL1490578 41418 3 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 7 2.1 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)O nan
135436946 41428 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 2 5 5.6 CSc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)cc1 nan
CHEMBL1490651 41428 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 2 5 5.6 CSc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)cc1 nan
2857238 41597 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 2 3 4.3 CC(Oc1ccccc1)C(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 nan
CHEMBL1491753 41597 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 2 3 4.3 CC(Oc1ccccc1)C(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 nan
3913191 41762 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 2 6 2.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc(O)nc2)c1 nan
CHEMBL1493081 41762 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 2 6 2.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc(O)nc2)c1 nan
16009715 41920 11 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
CHEMBL1494680 41920 11 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
252183 42093 18 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 3 3 7 -0.3 O=C1NC(=O)C(=NNc2ccc([N+](=O)[O-])cc2)C(=O)N1 nan
CHEMBL1496411 42093 18 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 3 3 7 -0.3 O=C1NC(=O)C(=NNc2ccc([N+](=O)[O-])cc2)C(=O)N1 nan
4023603 42577 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
4921719 42577 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
CHEMBL1500596 42577 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
2100904 43091 5 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 6 3.9 Cc1nn(CCc2nn[nH]n2)c2nc(-c3ccc(Br)cc3)cc(C(F)(F)F)c12 nan
CHEMBL1505221 43091 5 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 6 3.9 Cc1nn(CCc2nn[nH]n2)c2nc(-c3ccc(Br)cc3)cc(C(F)(F)F)c12 nan
1103129 43521 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 1 3 4.1 O=C(O)c1cccc(N2C(=O)c3cc4cccc(Br)c4cc3C2=O)c1 nan
CHEMBL1508887 43521 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 1 3 4.1 O=C(O)c1cccc(N2C(=O)c3cc4cccc(Br)c4cc3C2=O)c1 nan
15990473 43942 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.6 CCOc1ccccc1NC(=O)c1cn(C2CCCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1513016 43942 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.6 CCOc1ccccc1NC(=O)c1cn(C2CCCCC2)c(=O)c2c1c1ccccc1n2C nan
3858365 43962 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 6 5.7 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1513368 43962 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 6 5.7 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
16018934 43987 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 5.9 CCc1nnc(SCc2ccc(F)cc2Cl)c2cc3sc(C)cc3n12 nan
CHEMBL1513698 43987 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 5.9 CCc1nnc(SCc2ccc(F)cc2Cl)c2cc3sc(C)cc3n12 nan
16025722 44139 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 6 6.2 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3Cl)s1)C2 nan
CHEMBL1516031 44139 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 6 6.2 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3Cl)s1)C2 nan
5110655 44509 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 3.8 Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1519696 44509 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 3.8 Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
2161841 44856 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.5 Cc1nc(SCC(=O)N2CC(=O)Nc3ccccc32)nc(C)c1C nan
CHEMBL1522742 44856 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.5 Cc1nc(SCC(=O)N2CC(=O)Nc3ccccc32)nc(C)c1C nan
1238361 44988 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 1 5 6.5 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL1523965 44988 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 1 5 6.5 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(C(F)(F)F)c1 nan
20904542 45124 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 1.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccco3)nnc12 nan
CHEMBL1525378 45124 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 1.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccco3)nnc12 nan
2592811 45167 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 4 0 7 2.5 O=[N+]([O-])c1cc2c(c(CSc3ncccn3)c1)OCOC2 nan
CHEMBL1525704 45167 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 4 0 7 2.5 O=[N+]([O-])c1cc2c(c(CSc3ncccn3)c1)OCOC2 nan
6078768 45180 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 5 4.9 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(C)cc2)c(C)c1 nan
CHEMBL1525799 45180 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 5 4.9 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(C)cc2)c(C)c1 nan
1147569 45188 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 7 3.6 COc1cc(SC)ccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
CHEMBL1525877 45188 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 7 3.6 COc1cc(SC)ccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
4181953 45310 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 1 0 3 3.9 Cn1/c(=N\C(=O)c2ccc(F)cc2)sc2cc(Br)ccc21 nan
CHEMBL1526825 45310 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 1 0 3 3.9 Cn1/c(=N\C(=O)c2ccc(F)cc2)sc2cc(Br)ccc21 nan
5380406 45327 85 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 0 1 3 2.7 O=c1oc2cc(O)ccc2c2ccccc12 nan
CHEMBL1526978 45327 85 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 0 1 3 2.7 O=c1oc2cc(O)ccc2c2ccccc12 nan
5641185 45538 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 8 0.1 Cc1c(C(=O)NNc2cc(=O)n(C)c(=O)n2C)cccc1[N+](=O)[O-] nan
CHEMBL1528897 45538 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 8 0.1 Cc1c(C(=O)NNc2cc(=O)n(C)c(=O)n2C)cccc1[N+](=O)[O-] nan
1016791 45591 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 CC(C)c1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
CHEMBL1529358 45591 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 CC(C)c1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
7411882 45740 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)cc1 nan
CHEMBL1530681 45740 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)cc1 nan
16017598 45861 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)c1 nan
CHEMBL1531718 45861 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)c1 nan
16025817 45953 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 1 5 5.3 CCOc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1532579 45953 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 1 5 5.3 CCOc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
20939726 46033 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 0 7 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCOc2ccccc21 nan
CHEMBL1533261 46033 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 0 7 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCOc2ccccc21 nan
16033292 46183 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 6 5.4 CSc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1534658 46183 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 6 5.4 CSc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
135521540 46319 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 2 6 4.5 O=C(CCS(=O)(=O)c1ccccc1)Nc1ccc(-c2nc3ccccc3s2)c(O)c1 nan
CHEMBL1536204 46319 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 2 6 4.5 O=C(CCS(=O)(=O)c1ccccc1)Nc1ccc(-c2nc3ccccc3s2)c(O)c1 nan
2729862 46901 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 2 8 0.2 Cc1ccc(NCC(O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1541137 46901 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 2 8 0.2 Cc1ccc(NCC(O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
2487501 46948 30 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 2 6 1.3 Oc1nc2ccccc2n2c(S)nnc12 nan
CHEMBL1541468 46948 30 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 2 6 1.3 Oc1nc2ccccc2n2c(S)nnc12 nan
16194809 47293 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1nnc2ccc(-c3ccccn3)nn12)NCC1CCCO1 nan
CHEMBL1544280 47293 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1nnc2ccc(-c3ccccn3)nn12)NCC1CCCO1 nan
1866349 47413 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
661670 47413 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1406059 47413 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1545185 47413 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
15988305 48210 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 2.5 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
CHEMBL1552888 48210 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 2.5 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
1327631 48373 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CCc1ccc(OCC(=O)Nc2ccc3oc(-c4ccc(OC)cc4)nc3c2)cc1 nan
CHEMBL1555206 48373 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CCc1ccc(OCC(=O)Nc2ccc3oc(-c4ccc(OC)cc4)nc3c2)cc1 nan
16033300 48386 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 5.3 CCc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1555399 48386 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 5.3 CCc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
20970028 48466 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 5 1.7 CC(C)NS(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
CHEMBL1556192 48466 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 5 1.7 CC(C)NS(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
5202629 48684 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 7 2.4 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
CHEMBL1558116 48684 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 7 2.4 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
7411867 48984 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 0 4 4.3 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2)CC1 nan
CHEMBL1560888 48984 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 0 4 4.3 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2)CC1 nan
20923142 49170 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 1.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC(C)C nan
CHEMBL1562552 49170 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 1.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC(C)C nan
3505859 49172 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 8 2.3 CCN(CC)S(=O)(=O)c1ccc(C)c(NC(=O)Cn2cnc3cc([N+](=O)[O-])ccc3c2=O)c1 nan
CHEMBL1562557 49172 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 8 2.3 CCN(CC)S(=O)(=O)c1ccc(C)c(NC(=O)Cn2cnc3cc([N+](=O)[O-])ccc3c2=O)c1 nan
7524261 49272 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 2.6 CCS(=O)(=O)Nc1cccc(-c2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1563485 49272 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 2.6 CCS(=O)(=O)Nc1cccc(-c2ccc3nnc(-c4cccnc4)n3n2)c1 nan
5389817 49442 8 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 1 6 3.2 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCOC)C23C(=O)N(C)c2ccccc23)cc1 nan
CHEMBL1564945 49442 8 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 1 6 3.2 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCOC)C23C(=O)N(C)c2ccccc23)cc1 nan
1111955 49457 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 4.1 COc1ccc(-n2nc3ccc(NC(=O)COc4ccc(C)c(C)c4)cc3n2)cc1 nan
CHEMBL1565140 49457 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 4.1 COc1ccc(-n2nc3ccc(NC(=O)COc4ccc(C)c(C)c4)cc3n2)cc1 nan
15988272 49792 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 0 9 2.0 COC(=O)c1ccc(OC)c(Cn2c(=O)n(-c3ccc(C)cc3)c(=O)c3c2cnn3C)c1 nan
CHEMBL1567650 49792 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 0 9 2.0 COC(=O)c1ccc(OC)c(Cn2c(=O)n(-c3ccc(C)cc3)c(=O)c3c2cnn3C)c1 nan
15991345 49988 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 0 5 5.1 CSc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2ccc(C)cn2)cc1 nan
CHEMBL1569335 49988 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 0 5 5.1 CSc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2ccc(C)cn2)cc1 nan
15988962 50275 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCN(CCC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1571921 50275 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCN(CCC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
2483422 50779 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 6 1.1 Cn1c(CCC(=O)OCC(=O)NCC(F)(F)F)nc(=O)c2ccccc21 nan
CHEMBL1576699 50779 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 6 1.1 Cn1c(CCC(=O)OCC(=O)NCC(F)(F)F)nc(=O)c2ccccc21 nan
5070065 51257 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 1 8 5.1 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(C)=O)s2)c1 nan
CHEMBL1580853 51257 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 1 8 5.1 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(C)=O)s2)c1 nan
4295307 51331 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1ccccc1C1C(C(=O)c2cc3ccccc3o2)=C(O)C(=O)N1c1cc(C)on1 nan
CHEMBL1581437 51331 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1ccccc1C1C(C(=O)c2cc3ccccc3o2)=C(O)C(=O)N1c1cc(C)on1 nan
4808157 51524 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 0.5 COc1ccc(OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1583111 51524 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 0.5 COc1ccc(OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
6530035 52035 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 2.6 CCN(CC)S(=O)(=O)c1ccc(C(=O)NCCN2C(=O)S/C(=C\c3cccnc3)C2=O)cc1 nan
CHEMBL1587266 52035 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 2.6 CCN(CC)S(=O)(=O)c1ccc(C(=O)NCCN2C(=O)S/C(=C\c3cccnc3)C2=O)cc1 nan
15988968 52438 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)c(OC)c1 nan
CHEMBL1591154 52438 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)c(OC)c1 nan
16024517 52455 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 5.0 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C(C)C)cc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1591352 52455 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 5.0 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C(C)C)cc3)c3nc(C)ccc3c2=O)cc1 nan
16018826 52519 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 6 4.2 CCc1cccc(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1592153 52519 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 6 4.2 CCc1cccc(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
16010502 52599 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2F)CC1 nan
CHEMBL1593224 52599 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2F)CC1 nan
1191851 53142 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.0 CCc1ccccc1NC(=O)COc1ccc2oc(-c3ccc(OC)cc3)cc(=O)c2c1 nan
CHEMBL1598484 53142 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.0 CCc1ccccc1NC(=O)COc1ccc2oc(-c3ccc(OC)cc3)cc(=O)c2c1 nan
20888741 53333 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 7 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCCC2)s1 nan
CHEMBL1600180 53333 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 7 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCCC2)s1 nan
16018860 53540 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 6 4.6 Cc1ccc(NC(=O)CSc2nnc(C)n3c2cc2sccc23)c(C)c1 nan
CHEMBL1602197 53540 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 6 4.6 Cc1ccc(NC(=O)CSc2nnc(C)n3c2cc2sccc23)c(C)c1 nan
135460554 53779 7 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 7 2.5 CC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1604187 53779 7 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 7 2.5 CC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
16194880 53858 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 8 2.2 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)OC nan
CHEMBL1604935 53858 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 8 2.2 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)OC nan
2939815 54133 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2ccccc2n2c(SCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1607085 54133 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2ccccc2n2c(SCC(=O)NCC3CCCO3)nnc12 nan
16017570 54497 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 6 3.3 CN(Cc1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2cccc(Cl)c2)s1 nan
CHEMBL1610070 54497 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 6 3.3 CN(Cc1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2cccc(Cl)c2)s1 nan
7184628 54601 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccccc3)nnc12 nan
CHEMBL1611000 54601 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccccc3)nnc12 nan
20957175 54893 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 0 8 1.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)N1CCCCC1 nan
CHEMBL1613668 54893 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 0 8 1.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)N1CCCCC1 nan
11077 55006 35 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
CHEMBL1353221 55006 35 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
CHEMBL1616414 55006 35 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
686692 55026 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
CHEMBL1309275 55026 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
CHEMBL1616571 55026 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
694704 55314 58 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1373811 55314 58 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1618856 55314 58 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
3246720 55634 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
CHEMBL1445386 55634 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
CHEMBL1621717 55634 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
135439671 72172 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 2 9 0.1 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/c2c[nH]nc2-c2ccc(F)cc2)n(C)c1=O nan
CHEMBL1980641 72172 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 2 9 0.1 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/c2c[nH]nc2-c2ccc(F)cc2)n(C)c1=O nan
6187702 72744 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 6 2.6 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1ccc(N2CCOCC2)cc1 nan
CHEMBL1999641 72744 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 6 2.6 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1ccc(N2CCOCC2)cc1 nan
2058613 108341 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1cccc(OC)c1 nan
CHEMBL3198223 108341 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1cccc(OC)c1 nan
2947382 176292 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 1 5 1.8 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)C2CCCO2)c1 nan
CHEMBL459529 176292 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 1 5 1.8 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)C2CCCO2)c1 nan
3151452 199561 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 8 1.8 COCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL592554 199561 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 8 1.8 COCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3cccc(C)c3nc21 nan
3159270 201581 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 0 5 2.6 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCN(C)C)CC2 nan
CHEMBL605753 201581 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 0 5 2.6 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCN(C)C)CC2 nan
9687 185311 25 None 1 4 Human 6.8 pPotency = 6.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL1522836 185311 25 None 1 4 Human 6.8 pPotency = 6.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL485980 185311 25 None 1 4 Human 6.8 pPotency = 6.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
16682183 25314 1 None - 1 Human 5.8 pPotency = 5.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 2 0 5 4.6 CC(C)C(=O)N1CCC2(CC1)Oc1ccc(F)cc1C(=O)C21CC(c2ccc(Cl)cc2)=NO1 nan
CHEMBL1349353 25314 1 None - 1 Human 5.8 pPotency = 5.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 2 0 5 4.6 CC(C)C(=O)N1CCC2(CC1)Oc1ccc(F)cc1C(=O)C21CC(c2ccc(Cl)cc2)=NO1 nan
123807 868 54 None -2630 7 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
374 868 54 None -2630 7 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
379 868 54 None -2630 7 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
CHEMBL284969 868 54 None -2630 7 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
2099 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
4740 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
7095 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
CHEMBL628 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
DB00806 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
123683 3099 63 None -33884 5 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
422 3099 63 None -33884 5 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
CHEMBL119709 3099 63 None -33884 5 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
DB05511 3099 63 None -33884 5 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
2808307 10353 5 None -9 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 4 4.2 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)c1ccccc1C(=O)O nan
CHEMBL1162415 10353 5 None -9 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 4 4.2 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)c1ccccc1C(=O)O nan
16019490 10968 5 None -8 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)c1 nan
CHEMBL1173709 10968 5 None -8 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)c1 nan
2729861 20374 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 8 0.0 Cn1c(=O)c2c(ncn2CC(O)CNc2ccc(F)cc2)n(C)c1=O nan
CHEMBL1306604 20374 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 8 0.0 Cn1c(=O)c2c(ncn2CC(O)CNc2ccc(F)cc2)n(C)c1=O nan
713572 20477 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 0 2 4 3.0 CC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
CHEMBL1307433 20477 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 0 2 4 3.0 CC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
20884214 20764 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 1.4 CCC(C(=O)NCCN1CCOCC1)n1nc(C)n2c(cc3sccc32)c1=O nan
CHEMBL1309746 20764 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 1.4 CCC(C(=O)NCCN1CCOCC1)n1nc(C)n2c(cc3sccc32)c1=O nan
1831123 20817 8 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 3 1 7 5.2 Cc1nc2c(sc3nc(N4CCOCC4)c4c(c32)CC(C)(C)OC4)c(-c2ccccc2)c1C(=O)O nan
CHEMBL1310276 20817 8 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 3 1 7 5.2 Cc1nc2c(sc3nc(N4CCOCC4)c4c(c32)CC(C)(C)OC4)c(-c2ccccc2)c1C(=O)O nan
16194788 21004 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.2 O=C(CSc1nnc2ccc(-c3ccccc3)nn12)NCC1CCCO1 nan
CHEMBL1311747 21004 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.2 O=C(CSc1nnc2ccc(-c3ccccc3)nn12)NCC1CCCO1 nan
2820129 21102 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 2 4 2.2 CSc1sc(C(=O)NNC(C)=O)c2c1C=CCC2 nan
CHEMBL1312452 21102 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 2 4 2.2 CSc1sc(C(=O)NNC(C)=O)c2c1C=CCC2 nan
622563 21175 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 0 4 3.1 CN1c2ccc(C=O)c3c(C=O)ccc(c23)N(C)C1(C)C nan
CHEMBL1312974 21175 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 0 4 3.1 CN1c2ccc(C=O)c3c(C=O)ccc(c23)N(C)C1(C)C nan
4584575 21242 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 5 3.7 CC(C)N=C(S)n1cc(C(=O)c2cc(Cl)cc(Cl)c2O)cn1 nan
CHEMBL1313487 21242 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 5 3.7 CC(C)N=C(S)n1cc(C(=O)c2cc(Cl)cc(Cl)c2O)cn1 nan
16029652 21471 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 5.0 CCOc1ccc(NC(=O)c2sc3nc(-c4ccc(OC)cc4)cn3c2C)cc1 nan
CHEMBL1315982 21471 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 5.0 CCOc1ccc(NC(=O)c2sc3nc(-c4ccc(OC)cc4)cn3c2C)cc1 nan
1116235 21531 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 9 0.7 COc1cc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)cc1Cl nan
CHEMBL1316844 21531 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 9 0.7 COc1cc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)cc1Cl nan
16030395 21552 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
CHEMBL1317102 21552 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
16018828 21557 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.1 Cc1ccc(NC(=O)CSc2nncn3c2cc2sccc23)cc1F nan
CHEMBL1317182 21557 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.1 Cc1ccc(NC(=O)CSc2nncn3c2cc2sccc23)cc1F nan
16018832 21587 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1317561 21587 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
16025821 21624 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 1 5 4.9 CN(C)c1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1318005 21624 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 1 5 4.9 CN(C)c1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
1482206 21701 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 2.1 CS(=O)(=O)c1ccc(-c2cn3cc(C(=O)O)ccc3n2)cc1 nan
CHEMBL1318777 21701 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 2.1 CS(=O)(=O)c1ccc(-c2cn3cc(C(=O)O)ccc3n2)cc1 nan
1115262 21722 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 2 4 5.5 O=C(O)c1ccc(Nc2nc(-c3ccccc3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1318956 21722 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 2 4 5.5 O=C(O)c1ccc(Nc2nc(-c3ccccc3)c3cc(Br)ccc3n2)cc1 nan
16025794 21724 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.2 Cc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1318960 21724 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.2 Cc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
16021547 21738 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 6 2 8 1.8 NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(c3ncnc4c3nc3n4CCCCC3)CC2)cc1 nan
CHEMBL1319081 21738 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 6 2 8 1.8 NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(c3ncnc4c3nc3n4CCCCC3)CC2)cc1 nan
6287803 21743 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 6 4.6 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(Br)cc3)ccc2O1 nan
CHEMBL1319132 21743 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 6 4.6 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(Br)cc3)ccc2O1 nan
15988299 21766 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
CHEMBL1319322 21766 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
3152547 21952 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.2 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1F)c1ccco1 nan
CHEMBL1320921 21952 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.2 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1F)c1ccco1 nan
829953 22064 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 5 2.4 CCN(CC)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1321896 22064 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 5 2.4 CCN(CC)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
3147388 22230 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 1 4 2.9 Cc1cc(SCC(=O)NCC2CCCO2)nc2ccccc12 nan
CHEMBL1323473 22230 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 1 4 2.9 Cc1cc(SCC(=O)NCC2CCCO2)nc2ccccc12 nan
3154196 22331 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 8 -0.1 CN(CC(O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)c1ccccc1 nan
CHEMBL1324245 22331 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 8 -0.1 CN(CC(O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)c1ccccc1 nan
16019851 22392 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 11 1 9 1.9 CCOCCCNC(=O)CCc1nnc2ccc(N3CCN(c4cccc(OC)c4)CC3)nn12 nan
CHEMBL1324764 22392 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 11 1 9 1.9 CCOCCCNC(=O)CCc1nnc2ccc(N3CCN(c4cccc(OC)c4)CC3)nn12 nan
16018924 22417 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 0 5 5.2 CCc1nnc(SCc2cccc(F)c2)c2cc3sc(C)cc3n12 nan
CHEMBL1324960 22417 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 0 5 5.2 CCc1nnc(SCc2cccc(F)c2)c2cc3sc(C)cc3n12 nan
4156222 22476 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 6 2.5 O=C(c1cccc([N+](=O)[O-])c1)N1CCCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1 nan
CHEMBL1325527 22476 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 6 2.5 O=C(c1cccc([N+](=O)[O-])c1)N1CCCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1 nan
16012102 22618 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
CHEMBL1326931 22618 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
342695 22811 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 8 0.6 Cn1c([N+](=O)[O-])cnc1N1CCN(c2nncs2)C1=O nan
CHEMBL1328402 22811 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 8 0.6 Cn1c([N+](=O)[O-])cnc1N1CCN(c2nncs2)C1=O nan
5048043 22836 9 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1328648 22836 9 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
16195662 22928 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccncc4)n3n2)CC1 nan
CHEMBL1329498 22928 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccncc4)n3n2)CC1 nan
15988282 22965 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.0 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(F)cc3)nnc12 nan
CHEMBL1329775 22965 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.0 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(F)cc3)nnc12 nan
753118 23147 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1331202 23147 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1532594 23147 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
15989826 23274 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 1 6 3.2 Cc1ccc2nc(NCc3ccccc3Cl)c3nnnn3c2c1 nan
CHEMBL1332222 23274 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 1 6 3.2 Cc1ccc2nc(NCc3ccccc3Cl)c3nnnn3c2c1 nan
7120050 23871 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 3.9 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccc(F)cc1 nan
CHEMBL1336910 23871 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 3.9 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccc(F)cc1 nan
2997990 23909 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 10 -0.2 Cc1cc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(C)n1C nan
CHEMBL1337270 23909 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 10 -0.2 Cc1cc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(C)n1C nan
5827230 23988 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 9 3.4 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1338023 23988 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 9 3.4 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
4385163 24169 11 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 2 4 4.5 COc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1339561 24169 11 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 2 4 4.5 COc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
8030040 24342 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 2 5 3.2 O=C(NCCNC(=O)c1ccc(-c2ccc(Cl)c(Cl)c2)o1)c1cnccn1 nan
CHEMBL1341144 24342 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 2 5 3.2 O=C(NCCNC(=O)c1ccc(-c2ccc(Cl)c(Cl)c2)o1)c1cnccn1 nan
661441 24746 7 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1344527 24746 7 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1530959 24746 7 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
865623 24751 2 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 3 0 5 3.5 CN(C)c1ccc(-c2nnc(-c3cccs3)o2)cc1 nan
CHEMBL1344555 24751 2 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 3 0 5 3.5 CN(C)c1ccc(-c2nnc(-c3cccs3)o2)cc1 nan
2937580 24868 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 5 3.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(CC3CCCO3)C2c2ccccc2F)o1 nan
CHEMBL1345579 24868 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 5 3.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(CC3CCCO3)C2c2ccccc2F)o1 nan
1375907 25008 6 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 0 7 1.4 CCOC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
CHEMBL1346739 25008 6 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 0 7 1.4 CCOC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
5037672 25065 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 8 1.4 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cn2ccccc2n1 nan
CHEMBL1347181 25065 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 8 1.4 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cn2ccccc2n1 nan
3748480 25131 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1347701 25131 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
6463240 25153 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 9 0.6 CC(C)n1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1347878 25153 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 9 0.6 CC(C)n1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
4046369 25290 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCCC4)c3)nc2n1 nan
CHEMBL1349141 25290 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCCC4)c3)nc2n1 nan
5810234 25325 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1349428 25325 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
664152 25371 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 6 3.1 Cc1nc(SCC(=O)NCC2CCCO2)c2oc3ccccc3c2n1 nan
CHEMBL1349799 25371 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 6 3.1 Cc1nc(SCC(=O)NCC2CCCO2)c2oc3ccccc3c2n1 nan
4648816 25413 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 8 2.4 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1350189 25413 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 8 2.4 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
2081076 25444 18 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 1 5 3.3 O=c1c2c3c(sc2[nH]c(=S)n1Cc1ccco1)CCC3 nan
CHEMBL1350435 25444 18 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 1 5 3.3 O=c1c2c3c(sc2[nH]c(=S)n1Cc1ccco1)CCC3 nan
6618816 25509 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
CHEMBL1351035 25509 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
3117452 25514 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 3 1.4 Cc1c2ccccc2cc[n+]1CCCS(=O)(=O)[O-] nan
CHEMBL1351071 25514 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 3 1.4 Cc1c2ccccc2cc[n+]1CCCS(=O)(=O)[O-] nan
5809890 25638 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 1 6 3.8 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
CHEMBL1352143 25638 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 1 6 3.8 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
24794131 25650 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 0 8 2.7 CSc1ccccc1OCc1cc(C(=O)N2CCN(c3ncccn3)CC2)no1 nan
CHEMBL1352219 25650 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 0 8 2.7 CSc1ccccc1OCc1cc(C(=O)N2CCN(c3ncccn3)CC2)no1 nan
20903685 25697 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 0 8 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)CC1 nan
CHEMBL1352523 25697 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 0 8 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)CC1 nan
2322442 25736 6 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 5 3.3 Cc1noc(NS(=O)(=O)c2ccc(N3Cc4ccccc4C3=O)cc2)c1C nan
CHEMBL1352855 25736 6 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 5 3.3 Cc1noc(NS(=O)(=O)c2ccc(N3Cc4ccccc4C3=O)cc2)c1C nan
135490313 25884 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -0.6 Cc1cc(O)nc(SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)n1 nan
CHEMBL1353870 25884 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -0.6 Cc1cc(O)nc(SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)n1 nan
20923143 25996 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 6 1.6 CCCNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1354972 25996 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 6 1.6 CCCNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
1116268 26010 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 9 -0.1 COC(=O)c1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1355136 26010 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 9 -0.1 COC(=O)c1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
1003440 26126 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 2 5 5.9 Nc1c(C(=O)Nc2ccc(C(F)(F)F)cc2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1356669 26126 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 2 5 5.9 Nc1c(C(=O)Nc2ccc(C(F)(F)F)cc2)sc2nc(-c3cccs3)ccc12 nan
16024861 26206 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 4 3.0 CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1357771 26206 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 4 3.0 CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
25162722 26277 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 9 1.4 CCN(CC)c1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nncn1C nan
CHEMBL1358718 26277 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 9 1.4 CCN(CC)c1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nncn1C nan
4312795 26439 22 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 4 2.2 CC(Sc1cnc2ccccc2n1)C(=O)O nan
CHEMBL1360045 26439 22 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 4 2.2 CC(Sc1cnc2ccccc2n1)C(=O)O nan
3704657 26451 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 6 3.2 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2ncccn2)cc1 nan
CHEMBL1360163 26451 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 6 3.2 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2ncccn2)cc1 nan
24000844 26467 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.9 Cn1c2ccccc2c2nnc(SCC(=O)Nc3cccc(C(=O)O)c3)nc21 nan
CHEMBL1360279 26467 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.9 Cn1c2ccccc2c2nnc(SCC(=O)Nc3cccc(C(=O)O)c3)nc21 nan
791500 26489 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 5 3.4 CCOC(=O)c1c(C)nc(S)c(C#N)c1-c1ccccc1 nan
CHEMBL1360458 26489 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 5 3.4 CCOC(=O)c1c(C)nc(S)c(C#N)c1-c1ccccc1 nan
3178481 26668 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1362095 26668 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
5309057 26749 2 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 5 3.7 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccn2)CC1 nan
CHEMBL1362711 26749 2 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 5 3.7 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccn2)CC1 nan
16022478 26770 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 9 4.3 COc1cccc(NC(=O)c2ccc3c(=O)n4nc(Nc5ccccc5OC)sc4nc3c2)c1 nan
CHEMBL1362937 26770 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 9 4.3 COc1cccc(NC(=O)c2ccc3c(=O)n4nc(Nc5ccccc5OC)sc4nc3c2)c1 nan
20917857 27062 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.4 Cc1ccc(CNS(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)o1 nan
CHEMBL1365432 27062 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.4 Cc1ccc(CNS(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)o1 nan
2999882 27240 21 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 7 1 5 2.9 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1ccccc1 nan
CHEMBL1367025 27240 21 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 7 1 5 2.9 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1ccccc1 nan
1914729 27328 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 11 1 3 4.7 CC(=O)c1ccc(CCCCCCCCCC(=O)O)s1 nan
CHEMBL1367732 27328 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 11 1 3 4.7 CC(=O)c1ccc(CCCCCCCCCC(=O)O)s1 nan
3820161 27379 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccccc2F)o1 nan
CHEMBL1368082 27379 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccccc2F)o1 nan
135419062 27426 6 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 7 4.5 N#Cc1c(O)nc(SCC(=O)c2ccc(Br)cc2)nc1-c1cccs1 nan
CHEMBL1368444 27426 6 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 7 4.5 N#Cc1c(O)nc(SCC(=O)c2ccc(Br)cc2)nc1-c1cccs1 nan
3154099 27544 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 4.1 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1369329 27544 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 4.1 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
2443232 27780 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 1 5 6.4 O=C(COC(=O)c1cc(-c2ccccc2Cl)nc2ccccc12)Nc1ncc(C(F)(F)F)cc1Cl nan
CHEMBL1370986 27780 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 1 5 6.4 O=C(COC(=O)c1cc(-c2ccccc2Cl)nc2ccccc12)Nc1ncc(C(F)(F)F)cc1Cl nan
22548207 27812 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 0.8 CCOC(=O)CNC(=O)Cn1cnc2c(oc3ccccc32)c1=O nan
CHEMBL1371227 27812 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 0.8 CCOC(=O)CNC(=O)Cn1cnc2c(oc3ccccc32)c1=O nan
663879 28240 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 9 1 7 4.2 Cc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2ccc(OC(C)C)cc2)o1 nan
CHEMBL1374204 28240 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 9 1 7 4.2 Cc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2ccc(OC(C)C)cc2)o1 nan
20917681 28245 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 2.0 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)s1 nan
CHEMBL1374225 28245 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 2.0 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)s1 nan
4855374 28520 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 0 10 -0.3 CN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1(C#N)CCCCC1 nan
CHEMBL1376372 28520 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 0 10 -0.3 CN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1(C#N)CCCCC1 nan
20917816 28957 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 0 5 2.4 CC1CCN(S(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)CC1 nan
CHEMBL1380363 28957 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 0 5 2.4 CC1CCN(S(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)CC1 nan
661999 29042 14 None -5 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
CHEMBL1380975 29042 14 None -5 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
4342649 29155 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
5027943 29155 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
CHEMBL1381980 29155 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
135431552 29223 10 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 6 4.7 N#Cc1c(O)nc(SCc2ccc(Cl)cc2)nc1-c1cccs1 nan
CHEMBL1382616 29223 10 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 6 4.7 N#Cc1c(O)nc(SCc2ccc(Cl)cc2)nc1-c1cccs1 nan
921583 29616 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 1 1 3 4.3 Sc1nc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1386089 29616 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 1 1 3 4.3 Sc1nc(-c2ccccc2)nc2ccc(Br)cc12 nan
5428525 29937 25 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 1 5 1.8 COC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
CHEMBL1388510 29937 25 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 1 5 1.8 COC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
5824610 29985 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 7 1 5 3.1 CN(C)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1388949 29985 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 7 1 5 3.1 CN(C)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
16194879 30333 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c(OC)c1 nan
CHEMBL1391905 30333 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c(OC)c1 nan
1256976 30394 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 2 5 3.6 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3cccnc3)nc3ccc(Br)cc23)cc1 nan
CHEMBL1392432 30394 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 2 5 3.6 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3cccnc3)nc3ccc(Br)cc23)cc1 nan
7222624 30689 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)c(F)c3)nn2)s1 nan
CHEMBL1395178 30689 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)c(F)c3)nn2)s1 nan
16018363 30713 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 6 5.5 COc1ccc(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(OC)cc4)cn23)cc1 nan
CHEMBL1395439 30713 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 6 5.5 COc1ccc(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(OC)cc4)cn23)cc1 nan
15990211 30864 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 6 3.1 Fc1ccc(CNc2nc3ccc(Cl)cc3n3nnnc23)cc1 nan
CHEMBL1397707 30864 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 6 3.1 Fc1ccc(CNc2nc3ccc(Cl)cc3n3nnnc23)cc1 nan
7151328 30925 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 5 3.1 CCS(=O)(=O)Nc1ccc(-c2cn3c(C)csc3n2)cc1 nan
CHEMBL1398475 30925 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 5 3.1 CCS(=O)(=O)Nc1ccc(-c2cn3c(C)csc3n2)cc1 nan
20939725 31027 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 0 7 2.9 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)Oc2ccccc21 nan
CHEMBL1399426 31027 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 0 7 2.9 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)Oc2ccccc21 nan
16452548 31279 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)c1 nan
CHEMBL1401713 31279 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)c1 nan
3709623 31389 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)o1 nan
CHEMBL1402642 31389 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)o1 nan
5212778 31417 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
661982 31417 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
CHEMBL1402874 31417 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
3152754 31500 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 5 4.2 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccs1)c1ccco1 nan
CHEMBL1403767 31500 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 5 4.2 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccs1)c1ccco1 nan
2816622 31577 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 4.8 COc1ccc(-n2c(=S)[nH]c3sc(-c4ccccc4)cc3c2=O)c(OC)c1 nan
CHEMBL1404356 31577 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 4.8 COc1ccc(-n2c(=S)[nH]c3sc(-c4ccccc4)cc3c2=O)c(OC)c1 nan
7245568 31703 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 2.2 COc1ccc(NC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1405733 31703 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 2.2 COc1ccc(NC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
4184357 31721 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 6 1 9 4.3 O=C(O)c1ccc(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)cc1 nan
CHEMBL1405932 31721 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 6 1 9 4.3 O=C(O)c1ccc(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)cc1 nan
757946 31957 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 2 4.7 Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(=O)O nan
CHEMBL1407788 31957 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 2 4.7 Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(=O)O nan
3160259 32030 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 7 2.2 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCC(C)O nan
CHEMBL1408356 32030 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 7 2.2 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCC(C)O nan
1071246 32103 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 8 0.6 CCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1408937 32103 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 8 0.6 CCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
744304 32138 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 2 4 2.4 COc1ccc2[nH]c3c(S)ncnc3c2c1 nan
CHEMBL1409203 32138 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 2 4 2.4 COc1ccc2[nH]c3c(S)ncnc3c2c1 nan
3240452 32140 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 0.4 O=C(Cn1cnc2c(nnn2-c2ccc(F)cc2)c1=O)NCC1CCCO1 nan
CHEMBL1409223 32140 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 0.4 O=C(Cn1cnc2c(nnn2-c2ccc(F)cc2)c1=O)NCC1CCCO1 nan
15989908 32246 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1410062 32246 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
20923121 32286 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 2.0 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccco1 nan
CHEMBL1410345 32286 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 2.0 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccco1 nan
3998353 32479 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 8 1.0 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)nc2n1 nan
CHEMBL1412011 32479 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 8 1.0 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)nc2n1 nan
16034646 32572 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 3.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(Cl)cc3)nnc12 nan
CHEMBL1412706 32572 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 3.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(Cl)cc3)nnc12 nan
1145396 32670 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
5026856 32670 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
CHEMBL1413474 32670 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
652152 32813 19 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 2 1 3 2.7 COc1ccc2c(Cl)c(C(N)=O)sc2c1 nan
CHEMBL1414671 32813 19 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 2 1 3 2.7 COc1ccc2c(Cl)c(C(N)=O)sc2c1 nan
1004109 32931 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 2 4 5.4 Cc1ccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1F nan
CHEMBL1415733 32931 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 2 4 5.4 Cc1ccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1F nan
22334931 32991 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 4 3.5 O=C(O)CSc1nc2ccccc2nc1Cc1ccccc1F nan
CHEMBL1416271 32991 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 4 3.5 O=C(O)CSc1nc2ccccc2nc1Cc1ccccc1F nan
3953394 33096 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 8 1.5 O=C(CSc1nnc2ccccn12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1417177 33096 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 8 1.5 O=C(CSc1nnc2ccccn12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
24687828 33111 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 0 11 -0.1 COc1ccc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1 nan
CHEMBL1417257 33111 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 0 11 -0.1 COc1ccc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1 nan
7184635 33364 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1cccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1419486 33364 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1cccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
4796292 33409 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 6 1.1 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cnccn2)c1 nan
CHEMBL1419907 33409 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 6 1.1 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cnccn2)c1 nan
744542 33432 37 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 3 3.4 Cc1cc(SCCC(=O)O)nc2c(C)cccc12 nan
CHEMBL1420044 33432 37 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 3 3.4 Cc1cc(SCCC(=O)O)nc2c(C)cccc12 nan
3789487 33502 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 3.0 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(F)cc1)c1ccco1 nan
CHEMBL1420588 33502 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 3.0 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(F)cc1)c1ccco1 nan
1473006 33556 15 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 0 2 4.1 COc1cc2cc(Br)cc(Br)c2nc1C nan
CHEMBL1421084 33556 15 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 0 2 4.1 COc1cc2cc(Br)cc(Br)c2nc1C nan
22421602 33611 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 9 2 8 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1 nan
CHEMBL1421499 33611 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 9 2 8 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1 nan
20957484 33618 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 9 1.3 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
CHEMBL1421579 33618 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 9 1.3 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
7190683 33633 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1421703 33633 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
7190642 33776 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1422914 33776 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
741274 34006 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 0 7 0.6 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCC3 nan
CHEMBL1424800 34006 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 0 7 0.6 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCC3 nan
3816425 34092 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1425600 34092 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
7299201 34100 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.6 Cc1cccc(C)c1Nc1c(-c2ccc(N3CCOCC3)cc2)nc2cnccn12 nan
CHEMBL1425693 34100 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.6 Cc1cccc(C)c1Nc1c(-c2ccc(N3CCOCC3)cc2)nc2cnccn12 nan
5739077 34276 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 8 2.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1427088 34276 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 8 2.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3830309 34409 18 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 6 4.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1cc2ccccc2o1 nan
CHEMBL1428271 34409 18 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 6 4.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1cc2ccccc2o1 nan
20903609 34660 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 9 1 10 3.0 COc1cc(NC(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)cc(OC)c1 nan
CHEMBL1430241 34660 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 9 1 10 3.0 COc1cc(NC(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)cc(OC)c1 nan
990446 34687 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 9 2.1 COc1cccc(-n2nc3c(-n4ncc(C#N)c4N)nnc(C)c3c2C)c1 nan
CHEMBL1430459 34687 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 9 2.1 COc1cccc(-n2nc3c(-n4ncc(C#N)c4N)nnc(C)c3c2C)c1 nan
2809114 34836 5 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 4 4.7 CC(=O)c1sc(-c2ccccc2)cc1NS(=O)(=O)c1ccc(C)cc1 nan
CHEMBL1431741 34836 5 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 4 4.7 CC(=O)c1sc(-c2ccccc2)cc1NS(=O)(=O)c1ccc(C)cc1 nan
4968705 34988 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 0 10 -0.5 CN(C)S(=O)(=O)c1ccc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1433054 34988 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 0 10 -0.5 CN(C)S(=O)(=O)c1ccc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
16019549 35082 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 3 0 9 2.8 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(N1CCOCC1)c1sccc12 nan
CHEMBL1433993 35082 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 3 0 9 2.8 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(N1CCOCC1)c1sccc12 nan
20885693 35190 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 1 6 2.0 Cc1nn(CCCC(=O)NCCc2ccc(Cl)cc2)c(=O)c2nccn12 nan
CHEMBL1435443 35190 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 1 6 2.0 Cc1nn(CCCC(=O)NCCc2ccc(Cl)cc2)c(=O)c2nccn12 nan
4380857 35196 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1c(CN(C)C(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cnn1C nan
CHEMBL1435516 35196 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1c(CN(C)C(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cnn1C nan
5066674 35208 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 2.7 COC(=O)c1cc(NS(=O)(=O)c2cc(Br)cc3c2N(C(C)=O)CC3)cc(C(=O)OC)c1 nan
CHEMBL1435676 35208 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 2.7 COC(=O)c1cc(NS(=O)(=O)c2cc(Br)cc3c2N(C(C)=O)CC3)cc(C(=O)OC)c1 nan
3993922 35274 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 7 1.2 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1436555 35274 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 7 1.2 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2ccsc2n1 nan
16018682 35291 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.1 CCc1ccccc1NC(=O)CSc1nncn2c1cc1oc(C)cc12 nan
CHEMBL1436824 35291 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.1 CCc1ccccc1NC(=O)CSc1nncn2c1cc1oc(C)cc12 nan
16026770 35312 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 7 1.7 Cc1csc2nc(COC(=O)CNC(=O)c3ccc(F)cc3)cc(=O)n12 nan
CHEMBL1437080 35312 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 7 1.7 Cc1csc2nc(COC(=O)CNC(=O)c3ccc(F)cc3)cc(=O)n12 nan
90660425 35437 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 5 5.1 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccccc2F)cc1C nan
CHEMBL1438291 35437 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 5 5.1 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccccc2F)cc1C nan
663438 35606 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 6 1.4 O=S(=O)(c1cccc(-c2cn3cccnc3n2)c1)N1CCOCC1 nan
CHEMBL1439795 35606 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 6 1.4 O=S(=O)(c1cccc(-c2cn3cccnc3n2)c1)N1CCOCC1 nan
135544645 35615 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 7 3.7 N#Cc1c(O)nc(SCC(=O)Nc2cccc(Cl)c2)nc1-c1ccco1 nan
CHEMBL1439904 35615 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 7 3.7 N#Cc1c(O)nc(SCC(=O)Nc2cccc(Cl)c2)nc1-c1ccco1 nan
3363660 35755 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
4976974 35755 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
CHEMBL1441169 35755 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
2854626 35763 12 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CC(=O)C1=C(C)NC(SCC(=O)c2ccc(Cl)cc2)=C(C#N)C1CC(C)C nan
CHEMBL1441242 35763 12 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CC(=O)C1=C(C)NC(SCC(=O)c2ccc(Cl)cc2)=C(C#N)C1CC(C)C nan
20957185 35918 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 8 1.9 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccc(F)cc1 nan
CHEMBL1442625 35918 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 8 1.9 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccc(F)cc1 nan
812443 36112 47 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 2 1 4 3.2 C=CCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1444467 36112 47 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 2 1 4 3.2 C=CCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
20923160 36114 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccccc1CNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1444486 36114 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccccc1CNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
16745544 36492 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 1 5 2.5 COc1ccc(C2=CC3=C(Br)C(=O)C(C)(O)C(=O)C3=CO2)cc1 nan
CHEMBL1447877 36492 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 1 5 2.5 COc1ccc(C2=CC3=C(Br)C(=O)C(C)(O)C(=O)C3=CO2)cc1 nan
2376086 36556 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 5 2.6 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1448425 36556 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 5 2.6 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
16745680 36706 0 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 0 7 5.7 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1CC(C)C nan
CHEMBL1449527 36706 0 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 0 7 5.7 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1CC(C)C nan
16018684 36707 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 4.4 Cc1cc(C)c(NC(=O)CSc2nncn3c2cc2oc(C)cc23)c(C)c1 nan
CHEMBL1449543 36707 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 4.4 Cc1cc(C)c(NC(=O)CSc2nncn3c2cc2oc(C)cc23)c(C)c1 nan
1094076 36720 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.0 CC(=O)c1ccc(Nc2nc(=O)c3cccnc3s2)cc1 nan
CHEMBL1449615 36720 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.0 CC(=O)c1ccc(Nc2nc(=O)c3cccnc3s2)cc1 nan
3514089 36865 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1450861 36865 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
6619005 37083 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 5 1 7 4.4 Cc1c(N2C(=O)C(O)=C(C(=O)c3ccc(Br)cc3)C2c2cccnc2)c(=O)n(-c2ccccc2)n1C nan
CHEMBL1452549 37083 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 5 1 7 4.4 Cc1c(N2C(=O)C(O)=C(C(=O)c3ccc(Br)cc3)C2c2cccnc2)c(=O)n(-c2ccccc2)n1C nan
16194575 37260 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)s1 nan
CHEMBL1453968 37260 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)s1 nan
3178522 37325 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 0 9 0.2 CCCCn1c(SCC(=O)N2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1454485 37325 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 0 9 0.2 CCCCn1c(SCC(=O)N2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
2613266 37397 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 0 8 2.8 O=[N+]([O-])c1cc2c(c(CSc3nnc4ccccn34)c1)OCOC2 nan
CHEMBL1455089 37397 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 0 8 2.8 O=[N+]([O-])c1cc2c(c(CSc3nnc4ccccn34)c1)OCOC2 nan
1084466 37509 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 6 2.5 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
CHEMBL1456125 37509 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 6 2.5 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
20885676 37561 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 6 1.6 Cc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
CHEMBL1456629 37561 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 6 1.6 Cc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
3715206 37570 22 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 5 3.9 CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1456701 37570 22 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 5 3.9 CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
3252203 37723 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.2 O=C(CSc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
CHEMBL1457998 37723 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.2 O=C(CSc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
2939635 37826 38 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 247 3 1 3 3.1 Cc1cc(SC(C)C(=O)O)nc2ccccc12 nan
CHEMBL1458912 37826 38 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 247 3 1 3 3.1 Cc1cc(SC(C)C(=O)O)nc2ccccc12 nan
1442575 38066 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 6 1 4 3.7 CCCc1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1460883 38066 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 6 1 4 3.7 CCCc1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
4412828 38165 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 9 1 7 2.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)COc2ccc(C#N)cc2)c1 nan
CHEMBL1461851 38165 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 9 1 7 2.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)COc2ccc(C#N)cc2)c1 nan
1838049 38230 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 0.4 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1462354 38230 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 0.4 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
15945416 38974 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 3.5 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1468328 38974 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 3.5 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
4905842 38993 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 9 4.4 CSc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(SC)s2)cc1 nan
CHEMBL1468444 38993 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 9 4.4 CSc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(SC)s2)cc1 nan
6498441 39103 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 2.7 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NC1CCCC1 nan
CHEMBL1469364 39103 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 2.7 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NC1CCCC1 nan
4356276 39206 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 8 4.1 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1470300 39206 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 8 4.1 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
3776625 39261 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Br)c2)no1 nan
CHEMBL1470725 39261 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Br)c2)no1 nan
3186626 39282 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
CHEMBL1470851 39282 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
7256722 39606 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 2.4 Cc1ccc2nc(SCC(=O)Nc3ccc(F)cc3F)nc(=O)n2c1 nan
CHEMBL1474450 39606 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 2.4 Cc1ccc2nc(SCC(=O)Nc3ccc(F)cc3F)nc(=O)n2c1 nan
15990395 39754 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1cccc(NC(=O)c2nc3ccccc3n(C)c2=O)c1 nan
CHEMBL1476510 39754 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1cccc(NC(=O)c2nc3ccccc3n(C)c2=O)c1 nan
1506838 39799 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 4 3.1 Cc1cc(CNC(=O)COc2ccc(C#N)cc2)c2ccccc2n1 nan
CHEMBL1477044 39799 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 4 3.1 Cc1cc(CNC(=O)COc2ccc(C#N)cc2)c2ccccc2n1 nan
1471774 39842 24 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 3.0 CSc1cc(-c2ccccc2)nc(O)c1C#N nan
CHEMBL1477426 39842 24 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 3.0 CSc1cc(-c2ccccc2)nc(O)c1C#N nan
20970002 39852 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1 nan
CHEMBL1477514 39852 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1 nan
2931382 40146 14 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 2 5 2.1 COC(=O)c1sccc1NC(=O)C1CC=CCC1C(=O)O nan
CHEMBL1480089 40146 14 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 2 5 2.1 COC(=O)c1sccc1NC(=O)C1CC=CCC1C(=O)O nan
7120051 40153 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1480178 40153 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
16018856 40173 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 0 8 5.5 COc1ccc(-c2nc(CSc3nnc(C)n4c3cc3sccc34)c(C)o2)cc1 nan
CHEMBL1480328 40173 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 0 8 5.5 COc1ccc(-c2nc(CSc3nnc(C)n4c3cc3sccc34)c(C)o2)cc1 nan
3451317 40186 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 7 0.8 CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2nncn2C)c1 nan
CHEMBL1480436 40186 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 7 0.8 CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2nncn2C)c1 nan
3535142 40308 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 9 1 9 3.4 O=C(O)CCCCCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
CHEMBL1481365 40308 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 9 1 9 3.4 O=C(O)CCCCCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
3574141 40359 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 0 6 2.1 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(C(=O)OCC(=O)N2CCCC2)c1 nan
CHEMBL1481920 40359 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 0 6 2.1 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(C(=O)OCC(=O)N2CCCC2)c1 nan
5736472 40651 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 6 1 7 2.5 O=c1c2ccccc2nc(/C=C/c2ccc([N+](=O)[O-])o2)n1CCCO nan
CHEMBL1484332 40651 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 6 1 7 2.5 O=c1c2ccccc2nc(/C=C/c2ccc([N+](=O)[O-])o2)n1CCCO nan
5304429 40680 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 1 4 2.4 CC(=O)Nc1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1484671 40680 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 1 4 2.4 CC(=O)Nc1cccc(-c2cn3cccnc3n2)c1 nan
16012070 40716 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 7 2.9 Cc1cc(=O)n2nc(N3CCC(C(=O)Nc4c(C)cccc4C)CC3)sc2n1 nan
CHEMBL1484919 40716 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 7 2.9 Cc1cc(=O)n2nc(N3CCC(C(=O)Nc4c(C)cccc4C)CC3)sc2n1 nan
4399091 40718 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1ccccc1C1C(C(=O)c2ccc(C)o2)=C(O)C(=O)N1c1cc(C)on1 nan
CHEMBL1484932 40718 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1ccccc1C1C(C(=O)c2ccc(C)o2)=C(O)C(=O)N1c1cc(C)on1 nan
1387364 40773 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1485560 40773 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1576237 40773 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
6622721 41044 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 5 3.6 CNc1nc2c(-c3ccc(Cl)cc3)nnn2c2ccccc12 nan
CHEMBL1487831 41044 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 5 3.6 CNc1nc2c(-c3ccc(Cl)cc3)nnn2c2ccccc12 nan
1002526 41085 11 None -2 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 4 4.1 O=C(O)c1cc(-c2ccc3c(c2)OCO3)nc2ccc(Br)cc12 nan
CHEMBL1488092 41085 11 None -2 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 4 4.1 O=C(O)c1cc(-c2ccc3c(c2)OCO3)nc2ccc(Br)cc12 nan
7190684 41143 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1488468 41143 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
5881431 41242 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 1 7 4.2 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1489225 41242 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 1 7 4.2 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
2032322 41357 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 7 3.5 CCN(CC)CCCNc1nc(SC)nc2sc3c(c12)CCN(C)C3 nan
CHEMBL1490215 41357 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 7 3.5 CCN(CC)CCCNc1nc(SC)nc2sc3c(c12)CCN(C)C3 nan
755499 41464 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 7 1.0 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
CHEMBL1490891 41464 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 7 1.0 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
1283516 41656 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 7 0.9 O=c1[nH]n2cc(-n3cc([N+](=O)[O-])cn3)cnc2c1Br nan
CHEMBL1492212 41656 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 7 0.9 O=c1[nH]n2cc(-n3cc([N+](=O)[O-])cn3)cnc2c1Br nan
774862 41724 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 0 4 3.1 Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2ccccc21 nan
CHEMBL1492732 41724 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 0 4 3.1 Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2ccccc21 nan
3279901 41820 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 4 3.0 CC(=O)NC(CSc1cc(C)nc2ccc(Br)cc12)C(=O)O nan
CHEMBL1493652 41820 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 4 3.0 CC(=O)NC(CSc1cc(C)nc2ccc(Br)cc12)C(=O)O nan
4795978 41823 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 3.8 CN(C)S(=O)(=O)c1cccc(COc2ncnc3c(Cl)cc(Cl)cc23)c1 nan
CHEMBL1493688 41823 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 3.8 CN(C)S(=O)(=O)c1cccc(COc2ncnc3c(Cl)cc(Cl)cc23)c1 nan
15988336 41904 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1cccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1494501 41904 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1cccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
664285 41921 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 3 0 5 3.1 CC(=O)CSc1ncnc2c1oc1ccccc12 nan
CHEMBL1494683 41921 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 3 0 5 3.1 CC(=O)CSc1ncnc2c1oc1ccccc12 nan
748270 41963 46 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 0 4 2.2 Cc1nnc2c3ccccc3c(Cl)nn12 nan
CHEMBL1495086 41963 46 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 0 4 2.2 Cc1nnc2c3ccccc3c(Cl)nn12 nan
3186635 42073 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 0 9 -0.8 CCN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
CHEMBL1496152 42073 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 0 9 -0.8 CCN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
2561752 42309 17 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 3.2 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCS3 nan
CHEMBL1498284 42309 17 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 3.2 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCS3 nan
21552 42353 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 7 0.1 Cn1c(=O)c2c(nc(Cc3ccc(N)cc3)n2C)n(C)c1=O nan
CHEMBL1498782 42353 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 7 0.1 Cn1c(=O)c2c(nc(Cc3ccc(N)cc3)n2C)n(C)c1=O nan
7677140 42406 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 5 2.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1cccnc1 nan
CHEMBL1499143 42406 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 5 2.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1cccnc1 nan
2816379 42570 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 2.1 CCOC(=O)c1nnn2c1nc(SCC(C)=O)c1ccccc12 nan
CHEMBL1500551 42570 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 2.1 CCOC(=O)c1nnn2c1nc(SCC(C)=O)c1ccccc12 nan
18554434 42607 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 8 1.8 O=C(CSc1ncnc2c1nnn2Cc1ccccc1F)NCC1CCCO1 nan
CHEMBL1500823 42607 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 8 1.8 O=C(CSc1ncnc2c1nnn2Cc1ccccc1F)NCC1CCCO1 nan
5077853 42691 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 1 8 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1 nan
CHEMBL1501692 42691 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 1 8 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1 nan
7120056 42696 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1501734 42696 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
3884053 42852 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
661074 42852 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
CHEMBL1503060 42852 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
20957430 42889 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 3.2 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(NCc4ccc5c(c4)OCO5)nn23)c1 nan
CHEMBL1503367 42889 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 3.2 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(NCc4ccc5c(c4)OCO5)nn23)c1 nan
16452701 42995 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)n1 nan
CHEMBL1504372 42995 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)n1 nan
3457991 43125 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 5 1 8 3.2 Cc1ccc(F)cc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
CHEMBL1505540 43125 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 5 1 8 3.2 Cc1ccc(F)cc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
5198374 43139 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 7 2.4 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1505625 43139 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 7 2.4 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
986582 43241 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 3.2 CCc1ccc2oc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)c(C)c2c1 nan
CHEMBL1506399 43241 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 3.2 CCc1ccc2oc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)c(C)c2c1 nan
1811810 43274 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 2 3.5 C=CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
CHEMBL1506727 43274 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 2 3.5 C=CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
135528107 43798 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 5 3.2 CCN(CC(=O)NC(C)C)Cc1nc(O)c2cc(Br)cc(Br)c2n1 nan
CHEMBL1511291 43798 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 5 3.2 CCN(CC(=O)NC(C)C)Cc1nc(O)c2cc(Br)cc(Br)c2n1 nan
16496658 43916 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.1 CC1CCCN(C(=O)COC(=O)CNC(=O)c2sc3ccccc3c2Cl)C1 nan
CHEMBL1512634 43916 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.1 CC1CCCN(C(=O)COC(=O)CNC(=O)c2sc3ccccc3c2Cl)C1 nan
15988304 43994 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 0 8 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccccc4)CC3)nnc12 nan
CHEMBL1513808 43994 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 0 8 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccccc4)CC3)nnc12 nan
16026221 44110 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 1.2 CCOC(=O)C1CCN(C(=O)Cn2c(=O)cc(C)c3c(C)nn(C)c32)CC1 nan
CHEMBL1515615 44110 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 1.2 CCOC(=O)C1CCN(C(=O)Cn2c(=O)cc(C)c3c(C)nn(C)c32)CC1 nan
662069 44263 9 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 1.8 COC(=O)c1cc(Br)c(=O)n(-c2nccs2)c1 nan
CHEMBL1517409 44263 9 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 1.8 COC(=O)c1cc(Br)c(=O)n(-c2nccs2)c1 nan
3489758 44321 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 2 9 0.9 Cn1c(=O)c2ncn(CC(=O)N=Nc3c(O)[nH]c4ccccc34)c2n(C)c1=O nan
CHEMBL1518029 44321 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 2 9 0.9 Cn1c(=O)c2ncn(CC(=O)N=Nc3c(O)[nH]c4ccccc34)c2n(C)c1=O nan
16018686 44484 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 6 4.3 Cc1cc2c(cc3c(SCC(=O)Nc4ccc(Cl)cc4F)nncn32)o1 nan
CHEMBL1519470 44484 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 6 4.3 Cc1cc2c(cc3c(SCC(=O)Nc4ccc(Cl)cc4F)nncn32)o1 nan
20957225 44502 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 9 1.7 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)nc1 nan
CHEMBL1519640 44502 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 9 1.7 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)nc1 nan
2991435 44520 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 6 2.8 COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(Br)o2)c1 nan
CHEMBL1519787 44520 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 6 2.8 COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(Br)o2)c1 nan
5959865 44635 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 6 4.0 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(F)cc3)ccc2O1 nan
CHEMBL1520789 44635 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 6 4.0 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(F)cc3)ccc2O1 nan
4197564 44801 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 11 1 8 3.9 COc1cc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
CHEMBL1522190 44801 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 11 1 8 3.9 COc1cc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
5064245 44819 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 5 1 5 1.3 O=C(COc1ncnc2ccccc12)NCC1CCCO1 nan
CHEMBL1522316 44819 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 5 1 5 1.3 O=C(COc1ncnc2ccccc12)NCC1CCCO1 nan
3317909 44822 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
3536112 44822 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
CHEMBL1522365 44822 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
20957467 44897 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 9 1 8 1.8 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4)CC3)n2n1 nan
CHEMBL1523099 44897 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 9 1 8 1.8 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4)CC3)n2n1 nan
3242118 44910 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 1 5 2.6 Cc1nn(C(C)C(=O)O)c(=O)c2c1sc1ccccc12 nan
CHEMBL1523214 44910 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 1 5 2.6 Cc1nn(C(C)C(=O)O)c(=O)c2c1sc1ccccc12 nan
3178468 44968 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 8 0.6 CCn1c(SCC(=O)N2CCCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1523743 44968 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 8 0.6 CCn1c(SCC(=O)N2CCCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
774385 45191 55 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 192 1 1 4 2.3 Cc1ccccc1-c1nnc(S)o1 nan
CHEMBL1525902 45191 55 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 192 1 1 4 2.3 Cc1ccccc1-c1nnc(S)o1 nan
6156848 45204 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 6 3.9 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccccc3)ccc2O1 nan
CHEMBL1525999 45204 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 6 3.9 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccccc3)ccc2O1 nan
20923115 45464 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 0 6 3.1 CCN(c1ccccc1)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1528270 45464 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 0 6 3.1 CCN(c1ccccc1)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
1173803 45574 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 0 9 0.3 CCCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1529195 45574 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 0 9 0.3 CCCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
1150969 45575 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 2 6 3.2 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
CHEMBL1529199 45575 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 2 6 3.2 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
20957502 45642 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1cccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)c1 nan
CHEMBL1529803 45642 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1cccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)c1 nan
3146230 45827 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 6 2.7 Cc1sc2ncnc(SCC(=O)NCC3CCCO3)c2c1C nan
CHEMBL1531505 45827 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 6 2.7 Cc1sc2ncnc(SCC(=O)NCC3CCCO3)c2c1C nan
20888842 46092 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 9 1.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
CHEMBL1533752 46092 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 9 1.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
7677714 46094 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 5 3.2 Cc1ccc(C(=O)NCc2nnc3c(C(F)(F)F)cc(Cl)cn23)o1 nan
CHEMBL1533761 46094 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 5 3.2 Cc1ccc(C(=O)NCc2nnc3c(C(F)(F)F)cc(Cl)cn23)o1 nan
16018626 46141 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1ccc(NC(=O)CSc2nncn3c2cc2occc23)c(OC)c1 nan
CHEMBL1534283 46141 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1ccc(NC(=O)CSc2nncn3c2cc2occc23)c(OC)c1 nan
2415319 46143 28 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 5 4.0 O=C(O)c1ccccc1Sc1ncnc2sc3c(c12)CCC3 nan
CHEMBL1534296 46143 28 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 5 4.0 O=C(O)c1ccccc1Sc1ncnc2sc3c(c12)CCC3 nan
15988400 46172 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 7 3.0 CCn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
CHEMBL1534534 46172 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 7 3.0 CCn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
3559456 46275 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Br)c2)no1 nan
CHEMBL1535636 46275 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Br)c2)no1 nan
752859 46298 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 6 2.6 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccccc2)n1 nan
CHEMBL1535864 46298 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 6 2.6 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccccc2)n1 nan
1258096 46334 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 7 3.1 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)c(Cl)c1 nan
CHEMBL1536340 46334 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 7 3.1 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)c(Cl)c1 nan
5911396 46358 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 8 3.5 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)OCCO4)C2c2ccc(F)cc2)s1 nan
CHEMBL1536589 46358 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 8 3.5 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)OCCO4)C2c2ccc(F)cc2)s1 nan
2968508 46460 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 3.4 O=C(COc1ccccc1)NC(=S)Nc1cccc2cc(O)ccc12 nan
CHEMBL1537461 46460 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 3.4 O=C(COc1ccccc1)NC(=S)Nc1cccc2cc(O)ccc12 nan
973903 46620 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 3 7 1.5 O=C(NNc1nc(=O)c2cccnc2s1)c1ccccc1O nan
CHEMBL1538711 46620 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 3 7 1.5 O=C(NNc1nc(=O)c2cccnc2s1)c1ccccc1O nan
4786350 46673 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 4 0 6 2.6 COC(=O)c1ccc(COc2ncnc3ccccc23)o1 nan
CHEMBL1539182 46673 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 4 0 6 2.6 COC(=O)c1ccc(COc2ncnc3ccccc23)o1 nan
4199276 46680 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 10 -0.3 Cn1c(=O)c2nc(NNC(=O)c3ccc([N+](=O)[O-])cc3)cnc2n(C)c1=O nan
CHEMBL1539261 46680 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 10 -0.3 Cn1c(=O)c2nc(NNC(=O)c3ccc([N+](=O)[O-])cc3)cnc2n(C)c1=O nan
20957177 46705 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 8 2.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccccc1Cl nan
CHEMBL1539515 46705 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 8 2.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccccc1Cl nan
775376 46990 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 7 -0.1 Cn1c(=O)c2c(ncn2CC(=O)NC2CCCCC2)n(C)c1=O nan
CHEMBL1541812 46990 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 7 -0.1 Cn1c(=O)c2c(ncn2CC(=O)NC2CCCCC2)n(C)c1=O nan
2027988 47080 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)cc1 nan
CHEMBL1542663 47080 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)cc1 nan
7190638 47251 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 7 2.9 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccccc1 nan
CHEMBL1544038 47251 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 7 2.9 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccccc1 nan
5291252 47308 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 4 4.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
CHEMBL1544399 47308 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 4 4.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
3531704 47368 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 5.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccc(Oc3ccccc3)c2)no1 nan
CHEMBL1544885 47368 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 5.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccc(Oc3ccccc3)c2)no1 nan
1254436 47405 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 10 -0.3 Cn1c(=O)c2c(nc(Br)n2Cc2nnc(N)s2)n(C)c1=O nan
CHEMBL1545144 47405 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 10 -0.3 Cn1c(=O)c2c(nc(Br)n2Cc2nnc(N)s2)n(C)c1=O nan
20923178 47448 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)o1 nan
CHEMBL1545457 47448 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)o1 nan
2827527 47461 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 0 2 3.2 Cc1ccc2c(ccc(=S)n2C)c1 nan
CHEMBL1545583 47461 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 0 2 3.2 Cc1ccc2c(ccc(=S)n2C)c1 nan
4114707 47513 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2nnc(SCC(=O)NCC3CCCO3)n2c2ccccc12 nan
CHEMBL1546017 47513 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2nnc(SCC(=O)NCC3CCCO3)n2c2ccccc12 nan
6620293 47591 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 0 5 3.8 O=C(C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1)N1CCCC1 nan
CHEMBL1546743 47591 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 0 5 3.8 O=C(C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1)N1CCCC1 nan
2341870 47601 2 None -3 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 0 5 4.1 Cc1ccc(C)n1-c1ccc(-c2nnc3n2CCCCC3)s1 nan
CHEMBL1546820 47601 2 None -3 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 0 5 4.1 Cc1ccc(C)n1-c1ccc(-c2nnc3n2CCCCC3)s1 nan
2150404 47844 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 1 1 4 3.8 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccccc1 nan
CHEMBL1549101 47844 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 1 1 4 3.8 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccccc1 nan
2482804 47947 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 5 2 8 -0.4 C=CCNC(=O)NC(=O)COC(=O)c1nc2nccc(C)n2n1 nan
CHEMBL1549963 47947 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 5 2 8 -0.4 C=CCNC(=O)NC(=O)COC(=O)c1nc2nccc(C)n2n1 nan
7184632 48076 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1550958 48076 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
16030519 48094 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)cc1 nan
CHEMBL1551209 48094 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)cc1 nan
1116231 48198 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.4 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(Cl)c2Cl)n(C)c1=O nan
CHEMBL1552691 48198 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.4 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(Cl)c2Cl)n(C)c1=O nan
16031533 48208 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 6 4.5 CCc1ccccc1NC(=O)CSc1nnc(-c2ccc(OC)cc2)s1 nan
CHEMBL1552858 48208 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 6 4.5 CCc1ccccc1NC(=O)CSc1nnc(-c2ccc(OC)cc2)s1 nan
16033232 48218 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2cccc(Cl)c2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1552980 48218 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2cccc(Cl)c2)sc2ncnc(N(C)C3CCCCC3)c12 nan
2136319 48240 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
CHEMBL1553213 48240 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
16018758 48299 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 5 4.5 Cc1cc2c(cc3c(SCc4cccc(F)c4)nnc(C)n32)o1 nan
CHEMBL1554096 48299 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 5 4.5 Cc1cc2c(cc3c(SCc4cccc(F)c4)nnc(C)n32)o1 nan
4808155 48477 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 7 0.7 Cn1c(=O)c2c(ncn2CCOc2ccc(F)cc2)n(C)c1=O nan
CHEMBL1556293 48477 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 7 0.7 Cn1c(=O)c2c(ncn2CCOc2ccc(F)cc2)n(C)c1=O nan
664905 48616 16 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 3.4 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccco1 nan
CHEMBL1557499 48616 16 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 3.4 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccco1 nan
846378 48730 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 5 3.8 CN(C)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
CHEMBL1558527 48730 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 5 3.8 CN(C)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
20970070 48866 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 7 2.8 CCOc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
CHEMBL1559703 48866 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 7 2.8 CCOc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
749967 49067 54 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 208 2 1 5 2.0 COc1ccccc1-c1nnc(S)o1 nan
CHEMBL1561641 49067 54 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 208 2 1 5 2.0 COc1ccccc1-c1nnc(S)o1 nan
2816163 49238 22 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 2 0 7 0.8 CCOC(=O)c1nnn2c3ccccc3c(=O)n(C)c12 nan
CHEMBL1563125 49238 22 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 2 0 7 0.8 CCOC(=O)c1nnn2c3ccccc3c(=O)n(C)c12 nan
754624 49332 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 0 6 3.0 O=c1c2c(-c3ccc([N+](=O)[O-])cc3)csc2nc2n1CCC2 nan
CHEMBL1563900 49332 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 0 6 3.0 O=c1c2c(-c3ccc([N+](=O)[O-])cc3)csc2nc2n1CCC2 nan
20923125 49473 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)cc1 nan
CHEMBL1565225 49473 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)cc1 nan
5818870 49482 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4cccnc4)C3c3ccccc3F)ccc2O1 nan
CHEMBL1565288 49482 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4cccnc4)C3c3ccccc3F)ccc2O1 nan
702333 49969 16 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 0 1 3 2.9 Cn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
CHEMBL1569119 49969 16 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 0 1 3 2.9 Cn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
1072636 50307 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 1.0 CCn1c(SCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1572163 50307 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 1.0 CCn1c(SCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)nc2c1c(=O)n(C)c(=O)n2C nan
4912148 50315 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 8 3.6 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2)s1 nan
CHEMBL1572210 50315 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 8 3.6 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2)s1 nan
719137 50336 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 1 1 3 3.4 CCn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
CHEMBL1572461 50336 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 1 1 3 3.4 CCn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
22518619 50541 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 8 3.8 CC(C)OCCCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nc2nccnc2c1=O nan
CHEMBL1574369 50541 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 8 3.8 CC(C)OCCCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nc2nccnc2c1=O nan
3516975 50630 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2sccc2Br)nc(-n2cccc2)n1 nan
CHEMBL1575467 50630 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2sccc2Br)nc(-n2cccc2)n1 nan
2109682 50656 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 11 0.2 Cc1ccc(C)c(-n2nnnc2SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
CHEMBL1575697 50656 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 11 0.2 Cc1ccc(C)c(-n2nnnc2SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
16189479 50775 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 0 8 -0.2 Cn1c(=O)c(=O)n(C)c2cc(S(=O)(=O)N3CC(=O)N(CCc4ccccc4)C(=O)C3)ccc21 nan
CHEMBL1576683 50775 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 0 8 -0.2 Cn1c(=O)c(=O)n(C)c2cc(S(=O)(=O)N3CC(=O)N(CCc4ccccc4)C(=O)C3)ccc21 nan
1173783 50810 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCC(=O)Nc1ccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2CC)cc1 nan
CHEMBL1577034 50810 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCC(=O)Nc1ccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2CC)cc1 nan
2960985 51021 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
5740252 51021 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
9587839 51021 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
CHEMBL1578738 51021 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
3221467 51033 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 8 1 6 3.0 CCOC(=O)CNC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
CHEMBL1578803 51033 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 8 1 6 3.0 CCOC(=O)CNC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
6409200 51169 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 2 5 3.4 O=C(O)c1ccccc1CSc1n[nH]c2c3ccccc3nc-2n1 nan
CHEMBL1580121 51169 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 2 5 3.4 O=C(O)c1ccccc1CSc1n[nH]c2c3ccccc3nc-2n1 nan
20957463 51185 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 10 2 7 2.5 O=C(CCc1nnc2ccc(NCCCN3CCCC3=O)nn12)NCc1ccccc1Cl nan
CHEMBL1580225 51185 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 10 2 7 2.5 O=C(CCc1nnc2ccc(NCCCN3CCCC3=O)nn12)NCc1ccccc1Cl nan
929935 51269 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 1 2 6 4.2 CC(C)c1nc2sc3c(O)nc(S)nc3c2c2c1CCCC2 nan
CHEMBL1580962 51269 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 1 2 6 4.2 CC(C)c1nc2sc3c(O)nc(S)nc3c2c2c1CCCC2 nan
3220371 51277 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 6 2.9 CC(C)C(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
CHEMBL1581023 51277 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 6 2.9 CC(C)C(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
2916260 51354 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 10 0.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1581657 51354 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 10 0.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
1324776 51450 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 9 2 8 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2cc(OC)nc(OC)n2)cc1 nan
CHEMBL1582422 51450 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 9 2 8 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2cc(OC)nc(OC)n2)cc1 nan
4976300 51623 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 9 4.0 CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(OC)c2)s1 nan
CHEMBL1583844 51623 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 9 4.0 CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(OC)c2)s1 nan
5083492 51762 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 13 1 5 5.1 CC[N+](CC)(CCCCS(=O)(=O)[O-])CCNP1(=O)C=C(c2ccccc2)OC(c2ccccc2)=C1 nan
CHEMBL1585012 51762 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 13 1 5 5.1 CC[N+](CC)(CCCCS(=O)(=O)[O-])CCNP1(=O)C=C(c2ccccc2)OC(c2ccccc2)=C1 nan
6624747 51993 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 2.6 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccccc3)nnc12 nan
CHEMBL1586923 51993 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 2.6 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccccc3)nnc12 nan
2384712 52302 23 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 3 4.8 Brc1ccc(-c2nc3ccccc3s2)s1 nan
CHEMBL1589567 52302 23 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 3 4.8 Brc1ccc(-c2nc3ccccc3s2)s1 nan
16030403 52377 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 4 4.8 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCC(C)C)cc1 nan
CHEMBL1590296 52377 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 4 4.8 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCC(C)C)cc1 nan
16022890 52428 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 2 6 5.2 COc1cc2cc(CNc3ccccc3)c(=O)n(CC(=O)Nc3cccc(Cl)c3C)c2cc1OC nan
CHEMBL1590948 52428 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 2 6 5.2 COc1cc2cc(CNc3ccccc3)c(=O)n(CC(=O)Nc3cccc(Cl)c3C)c2cc1OC nan
16029271 52514 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 4 0 8 1.5 CCOC(=O)c1noc2ncn(Cc3cccc(C#N)c3)c(=O)c12 nan
CHEMBL1592100 52514 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 4 0 8 1.5 CCOC(=O)c1noc2ncn(Cc3cccc(C#N)c3)c(=O)c12 nan
3431356 52535 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 9 2 4 5.8 CCc1ccc(Nc2cc(C(=O)NCCCN(C)c3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1592367 52535 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 9 2 4 5.8 CCc1ccc(Nc2cc(C(=O)NCCCN(C)c3ccccc3)c3ccccc3n2)cc1 nan
16331440 52560 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 0 6 1.9 CC(C(=O)OCC(=O)N(C)C1(C#N)CCCCC1)N1C(=O)c2ccccc2C1=O nan
CHEMBL1592707 52560 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 0 6 1.9 CC(C(=O)OCC(=O)N(C)C1(C#N)CCCCC1)N1C(=O)c2ccccc2C1=O nan
22518595 52691 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.0 COc1ccccc1NC(=O)CSc1nc2nccnc2c(=O)n1Cc1cccs1 nan
CHEMBL1594419 52691 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.0 COc1ccccc1NC(=O)CSc1nc2nccnc2c(=O)n1Cc1cccs1 nan
3630300 52703 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 5 4.9 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(Cl)cc2)n1 nan
CHEMBL1594498 52703 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 5 4.9 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(Cl)cc2)n1 nan
16018788 52824 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 CCc1cccc(C)c1NC(=O)CSc1nnc(CC)n2c1cc1occc12 nan
CHEMBL1595485 52824 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 CCc1cccc(C)c1NC(=O)CSc1nnc(CC)n2c1cc1occc12 nan
135454734 52903 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 3 9 1.2 Nc1cc(O)nc(SCC(=O)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2Cl)n1 nan
CHEMBL1596208 52903 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 3 9 1.2 Nc1cc(O)nc(SCC(=O)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2Cl)n1 nan
3151377 52920 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCCC1 nan
CHEMBL1596336 52920 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCCC1 nan
2743162 53018 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)cc(Cl)c2)n1 nan
CHEMBL1597261 53018 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)cc(Cl)c2)n1 nan
5175738 53064 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 3 2 5 6.0 Nc1c(C(=O)Nc2ccc(F)cc2)sc2nc(-c3cccs3)cc(C(F)(F)F)c12 nan
CHEMBL1597711 53064 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 3 2 5 6.0 Nc1c(C(=O)Nc2ccc(F)cc2)sc2nc(-c3cccs3)cc(C(F)(F)F)c12 nan
16018618 53077 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)cc(NC(=O)CSc2nncn3c2cc2occc23)c1 nan
CHEMBL1597835 53077 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)cc(NC(=O)CSc2nncn3c2cc2occc23)c1 nan
2931308 53181 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 2.4 COC(=O)c1cc(C)sc1NC(=O)C1CC=CCC1C(=O)O nan
CHEMBL1598795 53181 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 2.4 COC(=O)c1cc(C)sc1NC(=O)C1CC=CCC1C(=O)O nan
16033260 53197 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1598947 53197 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
7202413 53365 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 8 1.2 Cc1nnc2sc(SCC(=O)N3CCC(C)CC3)nn2c1=O nan
CHEMBL1600469 53365 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 8 1.2 Cc1nnc2sc(SCC(=O)N3CCC(C)CC3)nn2c1=O nan
893043 53389 13 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 3 2.4 O=c1[nH]c(=S)c2c(n1-c1ccccc1)CCC2 nan
CHEMBL1600661 53389 13 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 3 2.4 O=c1[nH]c(=S)c2c(n1-c1ccccc1)CCC2 nan
15988297 53551 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.1 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1F nan
CHEMBL1602305 53551 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.1 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1F nan
20923199 53584 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N(C)Cc1ccco1 nan
CHEMBL1602602 53584 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N(C)Cc1ccco1 nan
2138501 53588 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 7 1.0 COc1ccc(C=O)cc1Cn1cnc2c(cnn2C)c1=O nan
CHEMBL1602628 53588 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 7 1.0 COc1ccc(C=O)cc1Cn1cnc2c(cnn2C)c1=O nan
16301839 53590 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 11 1.2 Cn1c(N)c(C(=O)CSc2nnc(NC3CCCCC3)s2)c(=O)n(C)c1=O nan
CHEMBL1602634 53590 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 11 1.2 Cn1c(N)c(C(=O)CSc2nnc(NC3CCCCC3)s2)c(=O)n(C)c1=O nan
2960993 53801 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
5740253 53801 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
9587840 53801 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
CHEMBL1604402 53801 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
5925277 53818 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 8 1.2 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCCOC)CC1 nan
CHEMBL1604541 53818 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 8 1.2 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCCOC)CC1 nan
2928283 53866 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCC4)c3nc12 nan
CHEMBL1605019 53866 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCC4)c3nc12 nan
6460757 54453 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 6 2.4 Cc1cc2c(SCC(=O)NCC3CCCO3)ncnc2s1 nan
CHEMBL1609708 54453 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 6 2.4 Cc1cc2c(SCC(=O)NCC3CCCO3)ncnc2s1 nan
15991073 54584 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
CHEMBL1610897 54584 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
7889635 54642 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 7 1.5 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3)cc(=O)n12 nan
CHEMBL1611331 54642 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 7 1.5 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3)cc(=O)n12 nan
778300 54817 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 2 1 10 -1.1 Cn1c(=O)c2c(ncn2Cc2nnc(N)s2)n(C)c1=O nan
CHEMBL1612871 54817 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 2 1 10 -1.1 Cn1c(=O)c2c(ncn2Cc2nnc(N)s2)n(C)c1=O nan
705485 55214 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
CHEMBL1321656 55214 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
CHEMBL1617945 55214 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
20279 55327 98 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
CHEMBL1619 55327 98 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
1187262 55601 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
CHEMBL1462585 55601 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
CHEMBL1621394 55601 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
44143728 60217 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
CHEMBL1553539 60217 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
CHEMBL1741041 60217 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
135641876 72136 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 10 -0.7 COc1cc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1O nan
CHEMBL1979668 72136 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 10 -0.7 COc1cc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1O nan
135475570 72629 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 7 2.3 CCN(CC)S(=O)(=O)c1cccc(N/N=C2/C(=O)Oc3ccccc3C2=O)c1 nan
CHEMBL1995496 72629 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 7 2.3 CCN(CC)S(=O)(=O)c1cccc(N/N=C2/C(=O)Oc3ccccc3C2=O)c1 nan
9632269 72892 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2cccnc2)n(C)c1=O nan
CHEMBL2004582 72892 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2cccnc2)n(C)c1=O nan
9553490 107970 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 9 -0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C/c2ccco2)n(C)c1=O nan
CHEMBL3194107 107970 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 9 -0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C/c2ccco2)n(C)c1=O nan
6905987 108312 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.5 Sc1nnc(-c2ccccn2)n1/N=C/c1ccc(-c2ccccc2Br)o1 nan
CHEMBL3198000 108312 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.5 Sc1nnc(-c2ccccn2)n1/N=C/c1ccc(-c2ccccc2Br)o1 nan
540540 108393 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 7 1.1 CC(=O)/N=c1\sc2nc3ccccc3nc2n1N(C(C)=O)C(C)=O nan
CHEMBL3198706 108393 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 7 1.1 CC(=O)/N=c1\sc2nc3ccccc3nc2n1N(C(C)=O)C(C)=O nan
5339637 108482 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 7 2 5 1.4 O=C(COc1ccccc1)NCC(=O)N/N=C/c1cccs1 nan
CHEMBL3199816 108482 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 7 2 5 1.4 O=C(COc1ccccc1)NCC(=O)N/N=C/c1cccs1 nan
9553411 108875 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 -0.0 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccccc2)n(C)c1=O nan
CHEMBL3210887 108875 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 -0.0 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccccc2)n(C)c1=O nan
9634938 108885 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccncc2)n(C)c1=O nan
CHEMBL3211064 108885 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccncc2)n(C)c1=O nan
1116825 184239 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 2.4 Cc1ccnc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
CHEMBL483773 184239 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 2.4 Cc1ccnc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
7190719 200923 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1ccc(CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL601822 200923 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1ccc(CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
3259 23328 55 None - 1 Human 3.8 pPotency = 3.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 836 0 2 5 6.1 O=C1OC2(c3ccccc31)c1cc(I)c(O)c(I)c1Oc1c2cc(I)c(O)c1I nan
CHEMBL1332616 23328 55 None - 1 Human 3.8 pPotency = 3.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 836 0 2 5 6.1 O=C1OC2(c3ccccc31)c1cc(I)c(O)c(I)c1Oc1c2cc(I)c(O)c1I nan
3228920 29707 5 None -31 2 Human 3.8 pPotency = 3.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 2 5 5.9 O=C(CSc1nc(-c2ccccc2F)nc2nc[nH]c12)Nc1c(Cl)cc(Cl)cc1Cl nan
CHEMBL1386739 29707 5 None -31 2 Human 3.8 pPotency = 3.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 2 5 5.9 O=C(CSc1nc(-c2ccccc2F)nc2nc[nH]c12)Nc1c(Cl)cc(Cl)cc1Cl nan
2099 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
4740 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
7095 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
CHEMBL628 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
DB00806 3024 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
3220395 19595 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 6 2.7 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
CHEMBL1300380 19595 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 6 2.7 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
16452711 19717 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 8 2.9 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)c1C nan
CHEMBL1301248 19717 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 8 2.9 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)c1C nan
4134237 19995 9 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 4 3.0 CC1CCCN(C(=O)CSc2cnc3ccccc3n2)C1 nan
CHEMBL1303471 19995 9 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 4 3.0 CC1CCCN(C(=O)CSc2cnc3ccccc3n2)C1 nan
2816749 20204 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 0 6 1.5 CCOC(=O)N1CCc2c(sc3ncn(C)c(=O)c23)C1 nan
CHEMBL1305245 20204 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 0 6 1.5 CCOC(=O)N1CCc2c(sc3ncn(C)c(=O)c23)C1 nan
225068 20307 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 2 6 0.5 CC(=O)Nc1ccc(Cc2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)cc1 nan
CHEMBL1306052 20307 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 2 6 0.5 CC(=O)Nc1ccc(Cc2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)cc1 nan
2377168 20645 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 6 1.7 NS(=O)(=O)c1ccc(CCNC(=O)CSc2ncnc3ccccc23)cc1 nan
CHEMBL1308771 20645 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 6 1.7 NS(=O)(=O)c1ccc(CCNC(=O)CSc2ncnc3ccccc23)cc1 nan
6311448 20864 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 2 6 2.6 CNc1ccc(/C=C(\C#N)C(=O)Nc2ccccn2)cc1[N+](=O)[O-] nan
CHEMBL1310631 20864 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 2 6 2.6 CNc1ccc(/C=C(\C#N)C(=O)Nc2ccccn2)cc1[N+](=O)[O-] nan
4454085 21070 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 8 1.1 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
CHEMBL1312229 21070 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 8 1.1 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
3269960 21132 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 9 3.7 O=C(O)CCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
CHEMBL1312645 21132 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 9 3.7 O=C(O)CCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
5811072 21165 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 7 3.8 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
CHEMBL1312900 21165 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 7 3.8 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
3719872 21246 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 3.8 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)no1 nan
CHEMBL1313510 21246 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 3.8 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)no1 nan
7151338 21325 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 2.8 CCS(=O)(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 nan
CHEMBL1314161 21325 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 2.8 CCS(=O)(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 nan
16010497 21367 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.0 COc1ccc(CCNC(=O)c2cnc3ccc(C)cn3c2=O)cc1OC nan
CHEMBL1314605 21367 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.0 COc1ccc(CCNC(=O)c2cnc3ccc(C)cn3c2=O)cc1OC nan
4119285 21449 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
CHEMBL1315733 21449 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
16020283 21487 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 5 4.1 CCOc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3s2)cc1 nan
CHEMBL1316147 21487 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 5 4.1 CCOc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3s2)cc1 nan
2645859 21520 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 6 2.6 Cc1cnc(C(=O)OCC(=O)c2ccc(Br)s2)cn1 nan
CHEMBL1316688 21520 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 6 2.6 Cc1cnc(C(=O)OCC(=O)c2ccc(Br)s2)cn1 nan
16019079 21594 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.2 CCc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1317634 21594 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.2 CCc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
16025698 21622 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 6.1 CC(NC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1)c1ccccc1 nan
CHEMBL1317991 21622 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 6.1 CC(NC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1)c1ccccc1 nan
16018836 21679 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 1 6 4.6 O=C(CSc1nncn2c1cc1sccc12)Nc1ccc(Br)cc1F nan
CHEMBL1318579 21679 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 1 6 4.6 O=C(CSc1nncn2c1cc1sccc12)Nc1ccc(Br)cc1F nan
658390 22102 23 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 2.7 CSc1sc(C(=O)O)c2c1C(=O)CCC2 nan
CHEMBL132222 22102 23 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 2.7 CSc1sc(C(=O)O)c2c1C(=O)CCC2 nan
4302597 22336 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 6 3.1 Cc1c(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)nn1C nan
CHEMBL1324305 22336 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 6 3.1 Cc1c(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)nn1C nan
16825458 22591 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1OC nan
CHEMBL1326698 22591 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1OC nan
961104 22898 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 5 2 5 1.8 CCOC(=O)c1[nH]cnc1C(=O)Nc1ccccc1OC nan
CHEMBL1329229 22898 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 5 2 5 1.8 CCOC(=O)c1[nH]cnc1C(=O)Nc1ccccc1OC nan
753118 23147 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1331202 23147 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1532594 23147 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
5302178 23621 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
CHEMBL1334923 23621 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
4213677 23722 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 2 9 2.3 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc5c(c4)OCO5)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1335629 23722 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 2 9 2.3 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc5c(c4)OCO5)c(=N)n(CC4CCCO4)c3nc12 nan
2410320 23957 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 6 2.5 Cc1ccc(S(=O)(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
CHEMBL1337652 23957 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 6 2.5 Cc1ccc(S(=O)(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
6624813 24275 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 7 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCCCC3)nnc12 nan
CHEMBL1340556 24275 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 7 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCCCC3)nnc12 nan
16189291 24427 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 0 8 2.6 CCOC(=O)C(CC)Sc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1341871 24427 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 0 8 2.6 CCOC(=O)C(CC)Sc1ccc2nnc(-c3cccnc3)n2n1 nan
2835302 24613 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 1 2 4 3.4 CCC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
CHEMBL1343308 24613 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 1 2 4 3.4 CCC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
9115295 24647 26 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 4 4.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1C(F)(F)F nan
CHEMBL1343609 24647 26 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 4 4.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1C(F)(F)F nan
874496 24707 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 4 2 2 4.0 CC(C)C(=O)Nc1ccc(Nc2ccccc2)cc1 nan
CHEMBL1344171 24707 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 4 2 2 4.0 CC(C)C(=O)Nc1ccc(Nc2ccccc2)cc1 nan
5040775 24727 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 5 1.5 CC1CCCCC1NC(=O)Cn1nnc2ccccc2c1=O nan
CHEMBL1344340 24727 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 5 1.5 CC1CCCCC1NC(=O)Cn1nnc2ccccc2c1=O nan
7190697 24796 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 9 1.0 CCOC(=O)CNC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1344913 24796 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 9 1.0 CCOC(=O)CNC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
1279973 24841 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 10 0.8 COCc1cc(C)nc(Sc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1C#N nan
CHEMBL1345308 24841 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 10 0.8 COCc1cc(C)nc(Sc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1C#N nan
16187878 24921 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 8 3.6 CCOC(=O)CC(NC(=O)CCc1c(C)nc2nc(C)nn2c1C)c1ccc(OC(C)C)cc1 nan
CHEMBL1346041 24921 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 8 3.6 CCOC(=O)CC(NC(=O)CCc1c(C)nc2nc(C)nn2c1C)c1ccc(OC(C)C)cc1 nan
4911180 24923 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 8 4.3 C=CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
CHEMBL1346060 24923 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 8 4.3 C=CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
6626039 25005 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 7 1 8 2.2 CCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
CHEMBL1346717 25005 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 7 1 8 2.2 CCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
4884017 25028 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 0 6 2.9 CCN1c2ccc(S(=O)(=O)N3CCOCC3)cc2N(Cc2ccc(OC)cc2)C1C nan
CHEMBL1346905 25028 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 0 6 2.9 CCN1c2ccc(S(=O)(=O)N3CCOCC3)cc2N(Cc2ccc(OC)cc2)C1C nan
5916900 25322 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1349404 25322 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
2421577 25415 5 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 0 5 3.2 COC(=O)CCc1c(C)c(C(=O)c2ccco2)c2ccccn12 nan
CHEMBL1350197 25415 5 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 0 5 3.2 COC(=O)CCc1c(C)c(C(=O)c2ccco2)c2ccccn12 nan
2429966 25471 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 0 7 2.8 COc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1OC nan
CHEMBL1350669 25471 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 0 7 2.8 COc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1OC nan
5921143 25660 17 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 10 1.5 CCCN1C(=O)/C(=C/c2c(N3CCNC(=O)C3CC(=O)OC)nc3c(C)cccn3c2=O)SC1=S nan
CHEMBL1352285 25660 17 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 10 1.5 CCCN1C(=O)/C(=C/c2c(N3CCNC(=O)C3CC(=O)OC)nc3c(C)cccn3c2=O)SC1=S nan
2926991 25691 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 4.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)n1 nan
CHEMBL1352465 25691 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 4.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)n1 nan
16015204 25956 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 4.5 COC(=O)c1c(-c2cccs2)csc1NC(=O)c1ccc(OC)c(OC)c1 nan
CHEMBL1354415 25956 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 4.5 COC(=O)c1c(-c2cccs2)csc1NC(=O)c1ccc(OC)c(OC)c1 nan
16030461 26008 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 4 4.2 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1355113 26008 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 4 4.2 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
23602530 26090 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 5 2.2 Cc1ccc(Cn2c(CCC(=O)O)nc3ncccc3c2=O)cc1 nan
CHEMBL1356159 26090 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 5 2.2 Cc1ccc(Cn2c(CCC(=O)O)nc3ncccc3c2=O)cc1 nan
16018072 26143 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 7 1 4 3.8 Cc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
CHEMBL1356862 26143 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 7 1 4 3.8 Cc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
1077055 26185 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 8 0.3 CC(=O)c1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1357427 26185 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 8 0.3 CC(=O)c1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
16021425 26198 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)c1 nan
CHEMBL1357639 26198 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)c1 nan
16030521 26212 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)c1 nan
CHEMBL1357883 26212 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)c1 nan
16030369 26237 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 4.9 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(C)cc2)c1 nan
CHEMBL1358199 26237 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 4.9 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(C)cc2)c1 nan
15987639 26263 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 4 5.5 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc2ccccc2F)cc1F nan
CHEMBL1358546 26263 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 4 5.5 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc2ccccc2F)cc1F nan
881482 26793 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 3 3.7 O=S(=O)(Nc1ccccn1)c1ccc(Cl)c2ccccc12 nan
CHEMBL1363117 26793 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 3 3.7 O=S(=O)(Nc1ccccn1)c1ccc(Cl)c2ccccc12 nan
3193431 26840 3 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 7 0 8 4.3 COc1ccc(Cn2nnnc2C(c2ccc3ncccc3c2)N2CCN(C3CCCCC3)CC2)cc1 nan
CHEMBL1363552 26840 3 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 7 0 8 4.3 COc1ccc(Cn2nnnc2C(c2ccc3ncccc3c2)N2CCN(C3CCCCC3)CC2)cc1 nan
1261960 26844 9 None -7 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 5 3.5 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)cc1 nan
CHEMBL1363571 26844 9 None -7 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 5 3.5 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)cc1 nan
7190718 26956 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1cccc(CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1364582 26956 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1cccc(CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
20884309 26963 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 8 1.1 CCc1nn(CC(=O)NCCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
CHEMBL1364643 26963 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 8 1.1 CCc1nn(CC(=O)NCCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
4152428 26998 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
CHEMBL1364957 26998 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
5109926 27032 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 2 8 2.6 COc1ccc(CCn2c(=N)c(C(=O)NCC3CCCO3)cc3c(=O)n4cccc(C)c4nc32)cc1 nan
CHEMBL1365247 27032 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 2 8 2.6 COc1ccc(CCn2c(=N)c(C(=O)NCC3CCCO3)cc3c(=O)n4cccc(C)c4nc32)cc1 nan
2959558 27035 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 3.3 CCOC(=O)N1CCN(C(=O)COc2ccc3ccccc3c2Br)CC1 nan
CHEMBL1365264 27035 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 3.3 CCOC(=O)N1CCN(C(=O)COc2ccc3ccccc3c2Br)CC1 nan
15988059 27091 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 1 10 2.6 COC(=O)c1cccc(Nc2nn3c(=O)c4cc5c(cc4nc3s2)OCO5)c1 nan
CHEMBL1365674 27091 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 1 10 2.6 COC(=O)c1cccc(Nc2nn3c(=O)c4cc5c(cc4nc3s2)OCO5)c1 nan
16015914 27097 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 2 0 4 6.1 Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)oc2cc(Br)ccc12 nan
CHEMBL1365703 27097 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 2 0 4 6.1 Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)oc2cc(Br)ccc12 nan
912209 27110 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 3 5 1.9 NC(S)=Nc1cccc(-c2nnc(S)o2)c1 nan
CHEMBL1365893 27110 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 3 5 1.9 NC(S)=Nc1cccc(-c2nnc(S)o2)c1 nan
3719648 27686 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 4.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc3ccccc23)s1 nan
CHEMBL1370349 27686 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 4.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc3ccccc23)s1 nan
1775727 27965 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 0 5 4.3 COc1ccccc1CN1COc2ccc3c(oc(=O)c4ccccc43)c2C1 nan
CHEMBL1372393 27965 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 0 5 4.3 COc1ccccc1CN1COc2ccc3c(oc(=O)c4ccccc43)c2C1 nan
16193912 28407 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 6 4.8 CCCCN(CC)CCCNC(=O)C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1 nan
CHEMBL1375345 28407 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 6 4.8 CCCCN(CC)CCCNC(=O)C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1 nan
2818996 28553 5 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.9 COc1ccc(-c2c(C#N)c(N)nc(Sc3ccc(Cl)cc3)c2C#N)cc1 nan
CHEMBL1376612 28553 5 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.9 COc1ccc(-c2c(C#N)c(N)nc(Sc3ccc(Cl)cc3)c2C#N)cc1 nan
20876288 29161 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 5 3.5 Cc1ccc(CN2CCSc3ccc(C(=O)NCCCN4CCN(C)CC4)cc32)cc1 nan
CHEMBL1382060 29161 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 5 3.5 Cc1ccc(CN2CCSc3ccc(C(=O)NCCCN4CCN(C)CC4)cc32)cc1 nan
4902824 29233 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
CHEMBL1382669 29233 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
408543 29586 42 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 3 1 3 2.4 O=C(O)CSc1ccc2ccccc2n1 nan
CHEMBL1385852 29586 42 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 3 1 3 2.4 O=C(O)CSc1ccc2ccccc2n1 nan
16452903 29611 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1ccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)cc1 nan
CHEMBL1386060 29611 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1ccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)cc1 nan
5866058 29636 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)c1 nan
CHEMBL1386260 29636 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)c1 nan
2219052 30113 10 None -3 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 6 4.2 CCCCn1nnc(NC(=O)c2sc3cc(Cl)ccc3c2Cl)n1 nan
CHEMBL1389959 30113 10 None -3 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 6 4.2 CCCCn1nnc(NC(=O)c2sc3cc(Cl)ccc3c2Cl)n1 nan
974402 30241 14 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 2 2 3.4 CC(C)NC(=S)NC(=O)c1ccc(-c2ccccc2)cc1 nan
CHEMBL1391097 30241 14 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 2 2 3.4 CC(C)NC(=S)NC(=O)c1ccc(-c2ccccc2)cc1 nan
4385170 30385 12 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 4 4.9 CCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1392345 30385 12 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 4 4.9 CCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
2492440 30418 26 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 3.4 Cc1ccccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
CHEMBL1392606 30418 26 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 3.4 Cc1ccccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
7207181 30466 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.9 O=C(CSc1ccc(-c2ccco2)nn1)NCc1ccc2c(c1)OCO2 nan
CHEMBL1393087 30466 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.9 O=C(CSc1ccc(-c2ccco2)nn1)NCc1ccc2c(c1)OCO2 nan
16025764 30678 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 0 3 4.6 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCCCC2)s1 nan
CHEMBL1395096 30678 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 0 3 4.6 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCCCC2)s1 nan
5839687 30821 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 1.7 COCCNC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O nan
CHEMBL1397071 30821 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 1.7 COCCNC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O nan
5789902 30883 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 5 4.0 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
CHEMBL1397920 30883 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 5 4.0 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
3288231 30904 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 4 5.7 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
CHEMBL1398189 30904 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 4 5.7 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
15991174 30934 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 3 3 7 1.6 Cc1cc(Nc2ccc(C(=O)O)c(O)c2)n2ncnc2n1 nan
CHEMBL1398548 30934 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 3 3 7 1.6 Cc1cc(Nc2ccc(C(=O)O)c(O)c2)n2ncnc2n1 nan
16025760 31066 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1399794 31066 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
135444909 31127 10 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 8 3 10 3.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)cc2)n1 nan
CHEMBL1400344 31127 10 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 8 3 10 3.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)cc2)n1 nan
16023027 31154 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
CHEMBL1400601 31154 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
2005962 31160 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 7 3.5 CC(C)OCCCN1CN(S(=O)(=O)c2cccs2)c2nc3ccccc3nc21 nan
CHEMBL1400661 31160 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 7 3.5 CC(C)OCCCN1CN(S(=O)(=O)c2cccs2)c2nc3ccccc3nc21 nan
4176332 31197 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 3 1 5 3.6 CN1CCN(NC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)CC1 nan
CHEMBL1401042 31197 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 3 1 5 3.6 CN1CCN(NC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)CC1 nan
7693269 31237 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 1 1 4.1 O=C(c1cc2cc(Br)ccc2[nH]1)N1CCc2ccccc21 nan
CHEMBL1401345 31237 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 1 1 4.1 O=C(c1cc2cc(Br)ccc2[nH]1)N1CCc2ccccc21 nan
1842681 32586 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 0 8 1.2 CCOC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1412841 32586 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 0 8 1.2 CCOC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
3159273 32774 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 5 3.0 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCCN(C)C)CC2 nan
CHEMBL1414335 32774 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 5 3.0 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCCN(C)C)CC2 nan
773430 32890 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 O=C(O)c1ccc2nc3c(nc2c1)-c1ccccc1C3=O nan
CHEMBL1415344 32890 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 O=C(O)c1ccc2nc3c(nc2c1)-c1ccccc1C3=O nan
1172271 33187 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 0 9 0.1 CCCn1c(SCC(=O)N2CCN(CC)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1417950 33187 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 0 9 0.1 CCCn1c(SCC(=O)N2CCN(CC)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
20957513 33356 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 12 2 8 2.6 CSc1ccc(CCNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1419386 33356 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 12 2 8 2.6 CSc1ccc(CCNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
656126 34308 5 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 4.1 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(C)c2C#N)sc(C(C)=O)c1C nan
CHEMBL1427319 34308 5 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 4.1 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(C)c2C#N)sc(C(C)=O)c1C nan
24792443 34384 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 5 3.1 CCc1nc(SCC(=O)NNC(=O)c2ccc(C)cc2)c2ccccc2n1 nan
CHEMBL1428040 34384 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 5 3.1 CCc1nc(SCC(=O)NNC(=O)c2ccc(C)cc2)c2ccccc2n1 nan
5295519 35085 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 10 0.1 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c1cc(=O)n(C)c(=O)n1C nan
CHEMBL1434105 35085 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 10 0.1 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c1cc(=O)n(C)c(=O)n1C nan
16959503 35169 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 9 2.5 CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
CHEMBL1435220 35169 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 9 2.5 CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
2448286 35192 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 11 1.6 Cn1c(N)c(C(=O)CSc2nn(-c3ccccc3)c(=S)s2)c(=O)n(C)c1=O nan
CHEMBL1435449 35192 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 11 1.6 Cn1c(N)c(C(=O)CSc2nn(-c3ccccc3)c(=S)s2)c(=O)n(C)c1=O nan
16018790 35317 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.6 CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2F)c2cc3occc3n12 nan
CHEMBL1437127 35317 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.6 CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2F)c2cc3occc3n12 nan
135401612 35579 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 3 7 1.5 Nc1cc(O)nc(SCC(=O)Nc2cccnc2Cl)n1 nan
CHEMBL1439558 35579 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 3 7 1.5 Nc1cc(O)nc(SCC(=O)Nc2cccnc2Cl)n1 nan
15990899 35689 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 9 1 10 5.2 COc1cc2nc(SCC(=O)Nc3cccc(C)c3)n3nc(CCn4c(C)nc5ccccc54)nc3c2cc1OC nan
CHEMBL1440596 35689 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 9 1 10 5.2 COc1cc2nc(SCC(=O)Nc3cccc(C)c3)n3nc(CCn4c(C)nc5ccccc54)nc3c2cc1OC nan
16034663 35714 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3)nnc12 nan
CHEMBL1440811 35714 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3)nnc12 nan
5898351 35885 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 6 4.2 Cc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
CHEMBL1442346 35885 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 6 4.2 Cc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
986518 35944 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 4 3.3 Cc1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2ccc(Cl)cc12 nan
CHEMBL1442810 35944 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 4 3.3 Cc1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2ccc(Cl)cc12 nan
16009462 35953 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.6 CC(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
CHEMBL1442959 35953 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.6 CC(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
7245567 35977 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1ccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1443187 35977 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1ccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
4920871 36366 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 7 1.9 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NCC1CCCO1 nan
CHEMBL1446831 36366 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 7 1.9 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NCC1CCCO1 nan
139030 36389 33 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 196 0 1 2 2.9 O=C1C=C(O)c2cccc3cccc1c23 nan
CHEMBL1446983 36389 33 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 196 0 1 2 2.9 O=C1C=C(O)c2cccc3cccc1c23 nan
771978 36400 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 6 1.2 O=C(Nc1ncccn1)c1ccc([N+](=O)[O-])o1 nan
CHEMBL1447058 36400 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 6 1.2 O=C(Nc1ncccn1)c1ccc([N+](=O)[O-])o1 nan
1511203 36478 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 2 7 2.6 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NC(C)(C)CO nan
CHEMBL1447724 36478 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 2 7 2.6 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NC(C)(C)CO nan
5310565 36878 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 8 1.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)N1CCOCC1 nan
CHEMBL1450965 36878 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 8 1.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)N1CCOCC1 nan
16457956 36995 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 4 8 1.1 CCN(CC)S(=O)(=O)c1cccc(C(=O)NNC(=O)c2ccc3nc(O)c(O)nc3c2)c1 nan
CHEMBL1451892 36995 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 4 8 1.1 CCN(CC)S(=O)(=O)c1cccc(C(=O)NNC(=O)c2ccc3nc(O)c(O)nc3c2)c1 nan
2173828 37587 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 3 5.6 CCN(CC)c1nc(-c2ccccc2Cl)c2cc(Br)ccc2n1 nan
CHEMBL1456908 37587 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 3 5.6 CCN(CC)c1nc(-c2ccccc2Cl)c2cc(Br)ccc2n1 nan
20904573 37894 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 1 8 2.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCN(Cc4ccccc4)CC3)nnc12 nan
CHEMBL1459467 37894 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 1 8 2.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCN(Cc4ccccc4)CC3)nnc12 nan
734076 37923 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 4 1 4 2.4 CCCC(=O)Nc1nc(C)c(C(C)=O)s1 nan
CHEMBL1459745 37923 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 4 1 4 2.4 CCCC(=O)Nc1nc(C)c(C(C)=O)s1 nan
1511643 37924 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 8 1.3 Cc1cc([N+](=O)[O-])nn1CC(=O)Nc1cccc2nonc12 nan
CHEMBL1459750 37924 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 8 1.3 Cc1cc([N+](=O)[O-])nn1CC(=O)Nc1cccc2nonc12 nan
1838806 38054 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 7 3.6 CCOc1cccc(Nc2cc3n(c(=O)n2)CCc2cc(OC)c(OC)cc2-3)c1 nan
CHEMBL1460751 38054 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 7 3.6 CCOc1cccc(Nc2cc3n(c(=O)n2)CCc2cc(OC)c(OC)cc2-3)c1 nan
16188836 38279 3 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 0 4 4.0 CC1=NOC(=O)/C1=C\c1ccc(-c2ccccc2Br)o1 nan
CHEMBL1462764 38279 3 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 0 4 4.0 CC1=NOC(=O)/C1=C\c1ccc(-c2ccccc2Br)o1 nan
3332154 38619 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 8 3.2 Cc1nc(N)sc1N=Nc1c(C)n(C)n(-c2ccccc2)c1=O nan
CHEMBL1465412 38619 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 8 3.2 Cc1nc(N)sc1N=Nc1c(C)n(C)n(-c2ccccc2)c1=O nan
20957223 38726 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 8 2.0 Cc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1466244 38726 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 8 2.0 Cc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
2350819 38732 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.3 Cc1cc(Br)ccc1SCC(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
CHEMBL1466307 38732 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.3 Cc1cc(Br)ccc1SCC(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
7190691 39073 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 8 3.1 CC(=O)c1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1469069 39073 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 8 3.1 CC(=O)c1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
1179824 39253 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 2 7 3.6 CCOC(=O)c1sc2ncnc(Nc3cccc(C(=O)O)c3)c2c1C nan
CHEMBL1470707 39253 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 2 7 3.6 CCOC(=O)c1sc2ncnc(Nc3cccc(C(=O)O)c3)c2c1C nan
7207497 39268 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 5 4.2 Cc1c(Cl)cccc1NC(=O)CSc1ccc(-c2cccnc2)nn1 nan
CHEMBL1470773 39268 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 5 4.2 Cc1c(Cl)cccc1NC(=O)CSc1ccc(-c2cccnc2)nn1 nan
16012892 39482 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 7 2.9 CCNC(=O)c1c(NC(=O)c2nc(S(=O)(=O)CC)ncc2Cl)sc2c1CCCC2 nan
CHEMBL1472696 39482 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 7 2.9 CCNC(=O)c1c(NC(=O)c2nc(S(=O)(=O)CC)ncc2Cl)sc2c1CCCC2 nan
16030433 39625 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 1 6 5.0 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)c1OC nan
CHEMBL1474670 39625 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 1 6 5.0 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)c1OC nan
4547893 39801 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 6 3.3 COc1ccccc1C(=O)Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1 nan
CHEMBL1477066 39801 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 6 3.3 COc1ccccc1C(=O)Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1 nan
1313916 40066 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1479446 40066 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
16021977 40434 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 6 4.5 CCOC(=O)c1ccc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2-n2cccc2)cc1 nan
CHEMBL1482573 40434 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 6 4.5 CCOC(=O)c1ccc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2-n2cccc2)cc1 nan
16025700 40653 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1cccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
CHEMBL1484349 40653 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1cccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
4969640 40684 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 1.5 COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1nncs1 nan
CHEMBL1484709 40684 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 1.5 COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1nncs1 nan
2267309 41189 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.8 Cc1cc(N)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
CHEMBL1488814 41189 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.8 Cc1cc(N)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
3157588 41459 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 3.7 CC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccccc1 nan
CHEMBL1490855 41459 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 3.7 CC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccccc1 nan
3755909 42044 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2ccc(Br)s2)nc(-n2cccc2)n1 nan
CHEMBL1495948 42044 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2ccc(Br)s2)nc(-n2cccc2)n1 nan
6501461 42663 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 9 2.7 CCC(Sc1nnc(-c2ccco2)n1C)C(=O)Nc1nnc(C)s1 nan
CHEMBL1501425 42663 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 9 2.7 CCC(Sc1nnc(-c2ccco2)n1C)C(=O)Nc1nnc(C)s1 nan
20968950 42713 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 0.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCC(C(N)=O)CC1)C(=O)CO2 nan
CHEMBL1501847 42713 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 0.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCC(C(N)=O)CC1)C(=O)CO2 nan
7692847 42854 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 6 3.1 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc2c(c1)OCO2 nan
CHEMBL1503072 42854 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 6 3.1 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc2c(c1)OCO2 nan
1243282 42972 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 2 1 5 4.6 Fc1ccc(-n2c(S)nnc2-c2ccc3ccccc3n2)cc1Cl nan
CHEMBL1504174 42972 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 2 1 5 4.6 Fc1ccc(-n2c(S)nnc2-c2ccc3ccccc3n2)cc1Cl nan
20888797 43193 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 9 1.5 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCN(CCO)CC2)s1 nan
CHEMBL1506053 43193 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 9 1.5 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCN(CCO)CC2)s1 nan
3965652 43215 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 5 3.6 Oc1nc(S)ncc1Oc1ccc(Cl)cc1Cl nan
CHEMBL1506226 43215 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 5 3.6 Oc1nc(S)ncc1Oc1ccc(Cl)cc1Cl nan
664243 43454 11 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.7 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)no1 nan
CHEMBL1508235 43454 11 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.7 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)no1 nan
1564171 43536 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 8 3.9 C=CCn1c(SCC(=O)Nc2sccc2C#N)nc2sc(C)c(C)c2c1=O nan
CHEMBL1509018 43536 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 8 3.9 C=CCn1c(SCC(=O)Nc2sccc2C#N)nc2sc(C)c(C)c2c1=O nan
660816 43700 54 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 5 3.2 COc1ccccc1-c1nnc(S)n1-c1ccccc1 nan
CHEMBL1510509 43700 54 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 5 3.2 COc1ccccc1-c1nnc(S)n1-c1ccccc1 nan
4736989 43859 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 7 1.4 O=C(O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1511802 43859 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 7 1.4 O=C(O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
16407031 43877 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 9 1 9 3.2 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCCN4CCOCC4)cc3c3ccnc2c31 nan
CHEMBL1512174 43877 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 9 1 9 3.2 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCCN4CCOCC4)cc3c3ccnc2c31 nan
16021393 43884 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 4 6.6 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(C(F)(F)F)c4)cc(C)c3c2)c1 nan
CHEMBL1512269 43884 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 4 6.6 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(C(F)(F)F)c4)cc(C)c3c2)c1 nan
16018932 44029 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 0 7 6.7 CCc1nnc(SCc2nc(-c3cccc(Cl)c3)oc2C)c2cc3sc(C)cc3n12 nan
CHEMBL1514500 44029 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 0 7 6.7 CCc1nnc(SCc2nc(-c3cccc(Cl)c3)oc2C)c2cc3sc(C)cc3n12 nan
20885685 44096 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccccc1CNC(=O)CCCn1nc(C)n2ccnc2c1=O nan
CHEMBL1515364 44096 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccccc1CNC(=O)CCCn1nc(C)n2ccnc2c1=O nan
16018754 44123 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 8 3.8 COc1cc(NC(=O)CSc2nnc(C)n3c2cc2oc(C)cc23)cc(OC)c1 nan
CHEMBL1515810 44123 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 8 3.8 COc1cc(NC(=O)CSc2nnc(C)n3c2cc2oc(C)cc23)cc(OC)c1 nan
4350514 45181 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 1.9 Cc1nc2ccccc2c(=O)n1NC(=O)Cc1ccc([N+](=O)[O-])cc1 nan
CHEMBL1525803 45181 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 1.9 Cc1nc2ccccc2c(=O)n1NC(=O)Cc1ccc([N+](=O)[O-])cc1 nan
135455188 45491 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 9 3.3 N#Cc1c(O)nc(SCC(=O)Nc2nnc(C(F)(F)F)s2)nc1-c1ccccc1 nan
CHEMBL1528492 45491 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 9 3.3 N#Cc1c(O)nc(SCC(=O)Nc2nnc(C(F)(F)F)s2)nc1-c1ccccc1 nan
3535143 45655 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 9 3.6 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4ccccc4n3)nc3ccsc3c2=O)CC1 nan
CHEMBL1529863 45655 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 9 3.6 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4ccccc4n3)nc3ccsc3c2=O)CC1 nan
16030435 45678 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 4 5.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccccc2Cl)cc1 nan
CHEMBL1530187 45678 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 4 5.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccccc2Cl)cc1 nan
54677747 45945 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 1 2 7 4.6 O=c1oc2ccccc2c(O)c1[C@H]1c2ccc(O)cc2Oc2c1c(=O)oc1ccccc21 nan
CHEMBL1532491 45945 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 1 2 7 4.6 O=c1oc2ccccc2c(O)c1[C@H]1c2ccc(O)cc2Oc2c1c(=O)oc1ccccc21 nan
6498569 45979 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 7 2 5 1.0 Cc1ccc(OCC(=O)NCCNC(=O)c2cnccn2)cc1C nan
CHEMBL1532759 45979 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 7 2 5 1.0 Cc1ccc(OCC(=O)NCCNC(=O)c2cnccn2)cc1C nan
6060971 45983 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 8 1 6 3.4 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2c2ccccc2)cc1 nan
CHEMBL1532782 45983 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 8 1 6 3.4 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2c2ccccc2)cc1 nan
3262927 46304 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 1.3 O=C(OCN1C(=O)c2ccccc2C1=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1F nan
CHEMBL1535967 46304 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 1.3 O=C(OCN1C(=O)c2ccccc2C1=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1F nan
6018171 46306 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 6 3.9 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1 nan
CHEMBL1535987 46306 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 6 3.9 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1 nan
7120055 46368 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 4.4 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1C nan
CHEMBL1536665 46368 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 4.4 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1C nan
2086676 46438 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 8 1.3 Cn1c(=O)c(C(=O)COc2ccc(C#N)cc2)c(N)n(Cc2ccccc2)c1=O nan
CHEMBL1537193 46438 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 8 1.3 Cn1c(=O)c(C(=O)COc2ccc(C#N)cc2)c(N)n(Cc2ccccc2)c1=O nan
20888841 46470 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 0 8 2.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CC)CC2)s1 nan
CHEMBL1537517 46470 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 0 8 2.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CC)CC2)s1 nan
22334156 46689 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 6 1 9 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1OC nan
CHEMBL1539318 46689 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 6 1 9 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1OC nan
3151316 46692 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1539382 46692 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CC4CCCO4)c3nc12 nan
17581317 46910 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 1 5 3.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc(Br)o1 nan
CHEMBL1541200 46910 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 1 5 3.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc(Br)o1 nan
6228228 47024 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 7 4.0 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2)s1 nan
CHEMBL1542130 47024 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 7 4.0 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2)s1 nan
2359872 47053 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 4 2.8 O=C(CSc1cnc2ccccc2n1)NC1CCCC1 nan
CHEMBL1542457 47053 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 4 2.8 O=C(CSc1cnc2ccccc2n1)NC1CCCC1 nan
2346972 47072 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 10 -1.0 CN(C)S(=O)(=O)c1cccc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
CHEMBL1542615 47072 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 10 -1.0 CN(C)S(=O)(=O)c1cccc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
135420430 47077 11 None -4 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 8 3.5 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1cc(C)on1 nan
CHEMBL1542646 47077 11 None -4 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 8 3.5 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1cc(C)on1 nan
1866349 47413 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
661670 47413 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1406059 47413 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1545185 47413 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
4876432 47438 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 2 6 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
CHEMBL1545378 47438 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 2 6 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
2595072 47439 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 6 1 4 3.1 O=C(CSc1ncnc2ccccc12)NCCc1ccccc1 nan
CHEMBL1545386 47439 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 6 1 4 3.1 O=C(CSc1ncnc2ccccc12)NCCc1ccccc1 nan
2115012 47506 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 10 0.2 CCCn1c(N)c(C(=O)COC(=O)c2c(C)noc2C)c(=O)n(C)c1=O nan
CHEMBL1545973 47506 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 10 0.2 CCCn1c(N)c(C(=O)COC(=O)c2c(C)noc2C)c(=O)n(C)c1=O nan
241512 47809 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 1 2 2 3.2 c1ccc(-c2ccc3c(c2)NCCN3)cc1 nan
CHEMBL1548782 47809 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 1 2 2 3.2 c1ccc(-c2ccc3c(c2)NCCN3)cc1 nan
16189384 48028 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 573 10 2 9 1.4 CSCCC(NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C)C(=O)NC1CCN(Cc2ccccc2)CC1 nan
CHEMBL1550614 48028 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 573 10 2 9 1.4 CSCCC(NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C)C(=O)NC1CCN(Cc2ccccc2)CC1 nan
16019521 48100 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 9 2.5 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCN(C)CC2)c2sccc23)c1 nan
CHEMBL1551283 48100 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 9 2.5 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCN(C)CC2)c2sccc23)c1 nan
6414933 48132 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 4.2 CCOC(=O)c1ccc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)cc1 nan
CHEMBL1551836 48132 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 4.2 CCOC(=O)c1ccc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)cc1 nan
16018808 48144 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 8 1 7 2.7 CCc1nnc(SC(CC)C(=O)NCCOC)c2cc3occc3n12 nan
CHEMBL1551969 48144 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 8 1 7 2.7 CCc1nnc(SC(CC)C(=O)NCCOC)c2cc3occc3n12 nan
5301786 48168 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 1 8 1.0 Cc1ccc(-c2c(C)n3c4c(=O)n(C)c(=O)n(C)c4nc3n2CCO)cc1 nan
CHEMBL1552221 48168 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 1 8 1.0 Cc1ccc(-c2c(C)n3c4c(=O)n(C)c(=O)n(C)c4nc3n2CCO)cc1 nan
1622536 48231 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 4.7 CCCCOC(=O)c1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 nan
CHEMBL1553105 48231 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 4.7 CCCCOC(=O)c1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 nan
16020969 48267 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 5.0 Cc1oc(-c2cccc(Br)c2)nc1CSc1nc2cccnc2[nH]1 nan
CHEMBL1553552 48267 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 5.0 Cc1oc(-c2cccc(Br)c2)nc1CSc1nc2cccnc2[nH]1 nan
4291583 48302 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 14 4 8 2.2 CSCCC(NS(=O)(=O)c1ccc2c(c1)Cc1cc(S(=O)(=O)NC(CCSC)C(=O)O)ccc1-2)C(=O)O nan
CHEMBL1554139 48302 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 14 4 8 2.2 CSCCC(NS(=O)(=O)c1ccc2c(c1)Cc1cc(S(=O)(=O)NC(CCSC)C(=O)O)ccc1-2)C(=O)O nan
20877874 48341 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 0 4 3.5 CCCN1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
CHEMBL1554696 48341 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 0 4 3.5 CCCN1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
16011310 48408 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 5 5.5 CCc1nnc(SCc2cccc(Cl)c2)c2cc3sccc3n12 nan
CHEMBL1555647 48408 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 5 5.5 CCc1nnc(SCc2cccc(Cl)c2)c2cc3sccc3n12 nan
16030467 48936 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 4 5.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)NCc1ccccc1Cl nan
CHEMBL1560326 48936 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 4 5.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)NCc1ccccc1Cl nan
2415608 48988 25 None -5 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 2 7 2.8 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3cc4c(cc3nc2Cl)OCCO4)cc1 nan
CHEMBL1560923 48988 25 None -5 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 2 7 2.8 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3cc4c(cc3nc2Cl)OCCO4)cc1 nan
15988392 49214 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.8 CCn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
CHEMBL1562908 49214 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.8 CCn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
3805026 49327 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Cl)cc2)no1 nan
CHEMBL1563863 49327 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Cl)cc2)no1 nan
6228410 49390 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 7 4.1 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2F)s1 nan
CHEMBL1564525 49390 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 7 4.1 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2F)s1 nan
4802105 49559 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 2.8 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCCC2)ccc1Cl nan
CHEMBL1565823 49559 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 2.8 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCCC2)ccc1Cl nan
225436 49806 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 198 0 1 3 1.2 O=C1c2ccccc2C(=O)c2[nH]cnc21 nan
CHEMBL1567800 49806 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 198 0 1 3 1.2 O=C1c2ccccc2C(=O)c2[nH]cnc21 nan
2054020 49916 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 7 4.7 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nc2ccccc2s1 nan
CHEMBL1568611 49916 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 7 4.7 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nc2ccccc2s1 nan
2883018 50079 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 0 1 5 1.6 N#Cc1c2n(c3c(N)ncnc13)CCCCC2 nan
CHEMBL1570092 50079 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 0 1 5 1.6 N#Cc1c2n(c3c(N)ncnc13)CCCCC2 nan
16018256 50213 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 CCOc1ccc(CCNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)cc1OCC nan
CHEMBL1571269 50213 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 CCOc1ccc(CCNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)cc1OCC nan
25163648 50347 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 4 4.3 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1c(F)cccc1Cl nan
CHEMBL1572593 50347 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 4 4.3 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1c(F)cccc1Cl nan
20957176 50425 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 0 9 0.2 CN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
CHEMBL1573164 50425 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 0 9 0.2 CN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
4200979 50751 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 7 1.0 COC(=O)CCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
CHEMBL1576536 50751 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 7 1.0 COC(=O)CCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
1132498 50963 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 5 5.1 Cc1ccc2nsnc2c1NC(=O)c1sc2ccccc2c1Cl nan
CHEMBL1578314 50963 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 5 5.1 Cc1ccc2nsnc2c1NC(=O)c1sc2ccccc2c1Cl nan
3220367 51219 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 1 6 2.4 COCCNC(=O)C(OC(=O)c1nsc(Cl)c1Cl)C(C)C nan
CHEMBL1580567 51219 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 1 6 2.4 COCCNC(=O)C(OC(=O)c1nsc(Cl)c1Cl)C(C)C nan
4343313 51419 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.2 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)n1 nan
CHEMBL1582134 51419 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.2 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)n1 nan
3338549 51435 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1582307 51435 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
20917770 51591 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 7 2.4 CN(Cc1ccco1)S(=O)(=O)c1ccc(CN2C(=O)c3cccnc3C2=O)s1 nan
CHEMBL1583626 51591 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 7 2.4 CN(Cc1ccco1)S(=O)(=O)c1ccc(CN2C(=O)c3cccnc3C2=O)s1 nan
18562929 51740 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 9 1.1 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCOCC4)nn23)cc1 nan
CHEMBL1584882 51740 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 9 1.1 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCOCC4)nn23)cc1 nan
2427540 52163 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 10 1.4 Cn1c(N)c(C(=O)CSc2nc3ccccc3c(=O)n2Cc2ccccc2)c(=O)n(C)c1=O nan
CHEMBL1588321 52163 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 10 1.4 Cn1c(N)c(C(=O)CSc2nc3ccccc3c(=O)n2Cc2ccccc2)c(=O)n(C)c1=O nan
20923114 52188 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 9 0 6 2.7 CCCN(CCC)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1588547 52188 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 9 0 6 2.7 CCCN(CCC)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
20885679 52392 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 1.9 Cc1nn(CCCC(=O)NCc2ccccc2Cl)c(=O)c2nccn12 nan
CHEMBL1590561 52392 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 1.9 Cc1nn(CCCC(=O)NCc2ccccc2Cl)c(=O)c2nccn12 nan
16023172 52416 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 3.4 CCCCNC(=O)CSc1nnc(C)c2c(C)n(-c3ccccc3)nc12 nan
CHEMBL1590852 52416 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 3.4 CCCCNC(=O)CSc1nnc(C)c2c(C)n(-c3ccccc3)nc12 nan
16016417 52457 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 3.4 Cc1cc(O)c(CN2CCN(c3ccccc3)CC2)c2oc(=O)cc(C)c12 nan
CHEMBL1591358 52457 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 3.4 Cc1cc(O)c(CN2CCN(c3ccccc3)CC2)c2oc(=O)cc(C)c12 nan
16009611 52615 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1cccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c1)c1ccc(F)cc1 nan
CHEMBL1593455 52615 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1cccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c1)c1ccc(F)cc1 nan
16453157 53073 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 8 2.7 O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1nn(-c2ccccc2)ccc1=O nan
CHEMBL1597782 53073 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 8 2.7 O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1nn(-c2ccccc2)ccc1=O nan
15990388 53280 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.4 Cc1c(NC(=O)c2nc3ccccc3n(C)c2=O)cccc1[N+](=O)[O-] nan
CHEMBL1599627 53280 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.4 Cc1c(NC(=O)c2nc3ccccc3n(C)c2=O)cccc1[N+](=O)[O-] nan
20917744 53359 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 7 2.3 Cc1ccc(CNS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)s2)o1 nan
CHEMBL1600418 53359 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 7 2.3 Cc1ccc(CNS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)s2)o1 nan
3252667 53375 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 4.8 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1600566 53375 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 4.8 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
5389427 53455 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 1 7 4.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3cc(C)on3)C2c2ccccc2OC)cc1 nan
CHEMBL1601252 53455 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 1 7 4.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3cc(C)on3)C2c2ccccc2OC)cc1 nan
723168 53781 42 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 4 1 4 4.2 O=C(O)Cc1sc(-c2ccccc2)nc1-c1cccs1 nan
CHEMBL1604196 53781 42 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 4 1 4 4.2 O=C(O)Cc1sc(-c2ccccc2)nc1-c1cccs1 nan
2235547 53920 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 3 1 5 2.4 CCOc1ccccc1-c1nnc(S)o1 nan
CHEMBL1605444 53920 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 3 1 5 2.4 CCOc1ccccc1-c1nnc(S)o1 nan
2927721 54070 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 2 7 2.6 CCOCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1606632 54070 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 2 7 2.6 CCOCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
3417563 54160 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3983329 54160 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1607267 54160 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3146573 54385 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 7 3.5 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1609156 54385 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 7 3.5 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
1941998 54418 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4F)sc3n2)c1 nan
CHEMBL1609358 54418 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4F)sc3n2)c1 nan
5389862 54550 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 6 3.5 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
CHEMBL1610515 54550 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 6 3.5 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
9550945 54713 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 2 0 5 3.2 CCOC(=O)N1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
CHEMBL1611989 54713 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 2 0 5 3.2 CCOC(=O)N1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
2120111 55673 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
CHEMBL1484562 55673 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
CHEMBL1622008 55673 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
1724830 55819 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
CHEMBL1520781 55819 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
CHEMBL1623209 55819 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
9619025 71940 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 10 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1OC nan
CHEMBL1973418 71940 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 10 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1OC nan
5065598 72557 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 0 8 2.9 CCOC(=O)Cn1/c(=N/C(=O)c2cccs2)sc2cc(C(=O)OC)ccc21 nan
CHEMBL1992834 72557 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 0 8 2.9 CCOC(=O)Cn1/c(=N/C(=O)c2cccs2)sc2cc(C(=O)OC)ccc21 nan
5286961 72808 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
9915251 72808 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL2001904 72808 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
95028 93779 31 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 2 0 6 0.5 Cn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O nan
CHEMBL24759 93779 31 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 2 0 6 0.5 Cn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O nan
135723776 107557 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 2 5 2.6 Cc1cc(O)nc(N/N=C/c2c(F)c(F)c(F)c(F)c2F)n1 nan
CHEMBL3189383 107557 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 2 5 2.6 Cc1cc(O)nc(N/N=C/c2c(F)c(F)c(F)c(F)c2F)n1 nan
5342833 107567 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 3 9 -2.3 Cn1c(=O)c2nc(N/N=C(/C#N)C(N)=O)[nH]c2n(C)c1=O nan
CHEMBL3189560 107567 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 3 9 -2.3 Cn1c(=O)c2nc(N/N=C(/C#N)C(N)=O)[nH]c2n(C)c1=O nan
4564145 107820 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(Br)cc2)n(C)c1C nan
CHEMBL3192424 107820 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(Br)cc2)n(C)c1C nan
135526880 108240 5 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
135643494 108240 5 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
137199718 108240 5 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
CHEMBL3197292 108240 5 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
9660607 108266 5 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 3 3.8 Cc1ccc(N2C(=O)CS/C2=N\C(=S)Nc2ccccc2)cc1 nan
CHEMBL3197507 108266 5 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 3 3.8 Cc1ccc(N2C(=O)CS/C2=N\C(=S)Nc2ccccc2)cc1 nan
9583775 108867 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 2 7 2.1 Nc1c(C(=O)N/N=C/c2ccc([N+](=O)[O-])cc2)cnn1-c1ccccc1 nan
CHEMBL3210811 108867 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 2 7 2.1 Nc1c(C(=O)N/N=C/c2ccc([N+](=O)[O-])cc2)cnn1-c1ccccc1 nan
3669734 198698 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 2.6 CCOC(=O)N1CCN(C(=O)CCCCn2c(=S)[nH]c3ccsc3c2=O)CC1 nan
CHEMBL582737 198698 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 2.6 CCOC(=O)N1CCN(C(=O)CCCCn2c(=S)[nH]c3ccsc3c2=O)CC1 nan
3324 206415 115 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 7 1 9 0.5 CC(=O)OCC(CCn1cnc2cnc(N)nc21)COC(C)=O nan
CHEMBL880 206415 115 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 7 1 9 0.5 CC(=O)OCC(CCn1cnc2cnc(N)nc21)COC(C)=O nan
1028 289 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
139148732 289 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
479 289 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
5816 289 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
CHEMBL679 289 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
DB00668 289 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
3289443 7033 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 5 5.0 Nc1c(C(=O)Nc2cccc(F)c2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1084955 7033 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 5 5.0 Nc1c(C(=O)Nc2cccc(F)c2)sc2nc(-c3cccs3)ccc12 nan
4112670 10448 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 3 4 5.5 O=C(NCCc1ccc(Cl)cc1)C1CCC(CNc2nc(=S)[nH]c3ccccc23)CC1 nan
CHEMBL1165197 10448 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 3 4 5.5 O=C(NCCc1ccc(Cl)cc1)C1CCC(CNc2nc(=S)[nH]c3ccccc23)CC1 nan
1003890 18329 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)c1 nan
CHEMBL1271075 18329 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)c1 nan
790786 19737 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 1 4.5 CCc1c(C)nc2ccc(Br)cc2c1Cl nan
CHEMBL1301385 19737 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 1 4.5 CCc1c(C)nc2ccc(Br)cc2c1Cl nan
6621843 19826 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 1 5 2.4 CCCNc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1302226 19826 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 1 5 2.4 CCCNc1nc2ccccc2n2c(C)nnc12 nan
926200 20050 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 4 4.0 Fc1cnc(N2CCc3ccccc32)nc1N1CCc2ccccc21 nan
CHEMBL1303908 20050 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 4 4.0 Fc1cnc(N2CCc3ccccc32)nc1N1CCc2ccccc21 nan
20881176 20338 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 1 7 2.3 CC(C)CCn1c(=O)c2ccccc2n2c(CCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1306246 20338 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 1 7 2.3 CC(C)CCn1c(=O)c2ccccc2n2c(CCC(=O)NCC3CCCO3)nnc12 nan
2220688 20489 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 0 6 4.3 Cc1ccc(-c2cc(C(=O)N3CCN(c4ncccn4)CC3)c3cc(Br)ccc3n2)o1 nan
CHEMBL1307526 20489 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 0 6 4.3 Cc1ccc(-c2cc(C(=O)N3CCN(c4ncccn4)CC3)c3cc(Br)ccc3n2)o1 nan
2962628 20580 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 5 5.0 CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2C(=O)c2ccccc2)c(Br)cc1OCC(=O)O nan
CHEMBL1308267 20580 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 5 5.0 CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2C(=O)c2ccccc2)c(Br)cc1OCC(=O)O nan
3774396 20798 3 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 1 3 6 1.7 CSc1nc(S)c2[nH]c(S)nc2n1 nan
CHEMBL1310138 20798 3 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 1 3 6 1.7 CSc1nc(S)c2[nH]c(S)nc2n1 nan
6247103 21111 20 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 4.4 COc1cc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc(OC)c1OC nan
CHEMBL1312514 21111 20 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 4.4 COc1cc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc(OC)c1OC nan
2927414 21468 23 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 8 1.9 CCOCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1315953 21468 23 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 8 1.9 CCOCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
16187669 21816 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 11 2 7 3.0 CCC1CCCCN1CCCNC(=O)CCCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
CHEMBL1319736 21816 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 11 2 7 3.0 CCC1CCCCN1CCCNC(=O)CCCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
1473386 21924 24 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 7 0.7 CCOC(=O)CSc1nc(=O)n2ccccc2n1 nan
CHEMBL1320637 21924 24 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 7 0.7 CCOC(=O)CSc1nc(=O)n2ccccc2n1 nan
2363935 21965 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 1 8 0.0 Cn1c(N)c(C(=O)COC(=O)CCc2ccccc2)c(=O)n(C)c1=O nan
CHEMBL1321001 21965 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 1 8 0.0 Cn1c(N)c(C(=O)COC(=O)CCc2ccccc2)c(=O)n(C)c1=O nan
1485315 21982 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 5 1.6 CS(=O)(=O)NNC(=O)c1cc2cc3ccccc3nc2s1 nan
CHEMBL1321144 21982 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 5 1.6 CS(=O)(=O)NNC(=O)c1cc2cc3ccccc3nc2s1 nan
20903731 22001 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 9 1 7 2.2 CC1CCN(c2ccc3nnc(CCC(=O)NCCCOC(C)C)n3n2)CC1 nan
CHEMBL1321331 22001 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 9 1 7 2.2 CC1CCN(c2ccc3nnc(CCC(=O)NCCCOC(C)C)n3n2)CC1 nan
16014625 22033 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.3 CC(=O)Nc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)cc1 nan
CHEMBL1321666 22033 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.3 CC(=O)Nc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)cc1 nan
16031994 22208 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 6 5.3 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nn2)s1 nan
CHEMBL1323264 22208 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 6 5.3 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nn2)s1 nan
857564 22265 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cccc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1323763 22265 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cccc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
1955570 22366 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccccc4C)sc3n2)c1 nan
CHEMBL1324540 22366 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccccc4C)sc3n2)c1 nan
16019112 22390 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 1 8 3.6 Cc1ccccc1NC(=O)Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
CHEMBL1324746 22390 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 1 8 3.6 Cc1ccccc1NC(=O)Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
20957487 22468 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1 nan
CHEMBL1325415 22468 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1 nan
654648 22499 13 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.4 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
CHEMBL1325819 22499 13 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.4 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
16411657 22654 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 4 0.9 CC1=NN(c2ccccc2)C(=O)C1/C=C1/NC(=S)NC1=O nan
CHEMBL1327209 22654 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 4 0.9 CC1=NN(c2ccccc2)C(=O)C1/C=C1/NC(=S)NC1=O nan
3725176 22877 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3cccc(C)c3)n2)cc1 nan
CHEMBL1329088 22877 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3cccc(C)c3)n2)cc1 nan
2965680 23780 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 4 4.4 CC(NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12)C1CCCO1 nan
CHEMBL1336138 23780 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 4 4.4 CC(NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12)C1CCCO1 nan
2928436 23809 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 2 8 1.7 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1Cc1ccco1 nan
CHEMBL1336360 23809 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 2 8 1.7 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1Cc1ccco1 nan
16023198 24034 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.0 Cc1nnc(SCC(=O)NCc2cccc(F)c2)c2nn(-c3ccccc3)c(C)c12 nan
CHEMBL1338308 24034 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.0 Cc1nnc(SCC(=O)NCc2cccc(F)c2)c2nn(-c3ccccc3)c(C)c12 nan
4907461 24152 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 5 3.7 CCCCNc1ncnc2sc3c(c12)CCN(CCC)C3 nan
CHEMBL1339392 24152 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 5 3.7 CCCCNc1ncnc2sc3c(c12)CCN(CCC)C3 nan
4173573 24597 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 2 8 0.8 Cc1cccn2c(=O)c3cc(C(N)=S)c(=N)n(CCCN4CCOCC4)c3nc12 nan
CHEMBL1343182 24597 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 2 8 0.8 Cc1cccn2c(=O)c3cc(C(N)=S)c(=N)n(CCCN4CCOCC4)c3nc12 nan
2439152 24610 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 0 5 2.2 Cc1ccc2nc(Cn3cc(C(F)(F)F)ccc3=O)cc(=O)n2c1 nan
CHEMBL1343295 24610 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 0 5 2.2 Cc1ccc2nc(Cn3cc(C(F)(F)F)ccc3=O)cc(=O)n2c1 nan
4918386 24960 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 2.5 Cc1cc(CNC(=O)C(C)n2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
CHEMBL1346435 24960 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 2.5 Cc1cc(CNC(=O)C(C)n2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
20904584 24976 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 9 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccccn4)CC3)nnc12 nan
CHEMBL1346578 24976 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 9 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccccn4)CC3)nnc12 nan
6112144 24991 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 9 1 7 3.5 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1346652 24991 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 9 1 7 3.5 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
5181544 25309 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 8 3.5 COC(=O)c1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1349309 25309 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 8 3.5 COC(=O)c1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
663780 25387 13 None -5 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 2 8 2.2 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CCCOC(C)C)c(=O)n2c1 nan
CHEMBL1349978 25387 13 None -5 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 2 8 2.2 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CCCOC(C)C)c(=O)n2c1 nan
860395 25396 47 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 3 3.8 O=C(O)c1cc(-c2cccs2)nc2ccc(F)cc12 nan
CHEMBL1350037 25396 47 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 3 3.8 O=C(O)c1cc(-c2cccs2)nc2ccc(F)cc12 nan
1013700 25587 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 0 3 3.6 O=C(COc1ccc2cc(Br)ccc2c1Br)N1CCOCC1 nan
CHEMBL1351652 25587 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 0 3 3.6 O=C(COc1ccc2cc(Br)ccc2c1Br)N1CCOCC1 nan
4137672 25731 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 4 4.1 O=C(O)c1ccccc1SCc1cn2cc(Br)ccc2n1 nan
CHEMBL1352828 25731 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 4 4.1 O=C(O)c1ccccc1SCc1cn2cc(Br)ccc2n1 nan
15991076 26028 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 6.6 COc1cc2ccccc2cc1C(=O)Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1 nan
CHEMBL1355303 26028 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 6.6 COc1cc2ccccc2cc1C(=O)Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1 nan
16019626 26112 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 8 3.2 Cc1ccc(-n2nnc(-c3nc(-c4cccs4)no3)c2N)c(C)c1 nan
CHEMBL1356419 26112 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 8 3.2 Cc1ccc(-n2nnc(-c3nc(-c4cccs4)no3)c2N)c(C)c1 nan
16033238 26164 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 5 5.6 Cc1cccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1C nan
CHEMBL1357134 26164 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 5 5.6 Cc1cccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1C nan
4084525 26482 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 0 6 3.9 CCOC(=O)c1sc2nc(C)nc(N3CCCCC3C)c2c1C nan
CHEMBL1360386 26482 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 0 6 3.9 CCOC(=O)c1sc2nc(C)nc(N3CCCCC3C)c2c1C nan
1130278 26512 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 4.0 Cc1ccc(NC(=O)CSc2nnc(COc3ccccc3C)o2)cc1 nan
CHEMBL1360712 26512 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 4.0 Cc1ccc(NC(=O)CSc2nnc(COc3ccccc3C)o2)cc1 nan
2112396 26954 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 7 4.0 CNS(=O)(=O)c1cccc(C(=O)OCC(=O)Nc2ccc(-c3nc4ccc(C)cc4s3)cc2)c1 nan
CHEMBL1364577 26954 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 7 4.0 CNS(=O)(=O)c1cccc(C(=O)OCC(=O)Nc2ccc(-c3nc4ccc(C)cc4s3)cc2)c1 nan
3244890 27739 14 None -5 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.7 O=C(O)CCc1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1370669 27739 14 None -5 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.7 O=C(O)CCc1ccc(-c2ccc(Br)cc2)o1 nan
135443907 28084 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 2 9 4.5 CCOc1ccc2nc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)sc2c1 nan
CHEMBL1373145 28084 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 2 9 4.5 CCOc1ccc2nc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)sc2c1 nan
16018180 28086 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(OC)c(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)c1 nan
CHEMBL1373157 28086 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(OC)c(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)c1 nan
2727621 28188 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 7 3.3 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccccc3)c(N)c12 nan
CHEMBL1373780 28188 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 7 3.3 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccccc3)c(N)c12 nan
16019289 28430 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 5 4.9 Cc1ccc(NC(=O)CSc2ccc(-c3cccs3)nn2)cc1Cl nan
CHEMBL1375486 28430 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 5 4.9 Cc1ccc(NC(=O)CSc2ccc(-c3cccs3)nn2)cc1Cl nan
2361888 28591 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc(O)c(C(=O)OCC(=O)N2CCCC2)c1 nan
CHEMBL1377052 28591 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc(O)c(C(=O)OCC(=O)N2CCCC2)c1 nan
887924 28675 9 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 4 4.8 Cc1ccc2c(Cl)c(C(=O)Nc3ccc4c(c3)OCO4)sc2c1 nan
CHEMBL1377850 28675 9 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 4 4.8 Cc1ccc2c(Cl)c(C(=O)Nc3ccc4c(c3)OCO4)sc2c1 nan
135527311 29164 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 8 3.7 COC(=O)CSc1nc(O)c2c(C(F)(F)F)cc(-c3cccs3)nc2n1 nan
CHEMBL1382080 29164 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 8 3.7 COC(=O)CSc1nc(O)c2c(C(F)(F)F)cc(-c3cccs3)nc2n1 nan
15987888 29429 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1384448 29429 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
54710218 29726 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 4 3.7 Cc1ccc(Sc2c(O)c3ccccc3n(C)c2=O)cc1 nan
CHEMBL1386873 29726 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 4 3.7 Cc1ccc(Sc2c(O)c3ccccc3n(C)c2=O)cc1 nan
4047539 29925 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 8 0.8 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1388441 29925 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 8 0.8 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
733870 30041 37 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 1 4 3.6 CC(=O)c1sc(NC(=O)c2ccc(Cl)cc2)nc1C nan
CHEMBL1389324 30041 37 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 1 4 3.6 CC(=O)c1sc(NC(=O)c2ccc(Cl)cc2)nc1C nan
829950 30155 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 5 1.6 CN(C)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1390362 30155 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 5 1.6 CN(C)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
5027542 30199 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 7 1.5 O=C(CN1C(=O)C2CC=CCC2C1=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1390760 30199 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 7 1.5 O=C(CN1C(=O)C2CC=CCC2C1=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
3634961 30313 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
4315628 30313 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
CHEMBL1391748 30313 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
5898126 30345 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 4.1 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccs2)cc1 nan
CHEMBL1392030 30345 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 4.1 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccs2)cc1 nan
4531942 30382 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 11 0.0 CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
CHEMBL1392325 30382 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 11 0.0 CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
1102249 30442 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 2 4 4.5 O=C(Nc1ccc(Br)cn1)c1cccc(C(=O)Nc2ccc(Br)cn2)c1 nan
CHEMBL1392808 30442 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 2 4 4.5 O=C(Nc1ccc(Br)cn1)c1cccc(C(=O)Nc2ccc(Br)cn2)c1 nan
16018254 30943 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 4 1.1 CNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
CHEMBL1398599 30943 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 4 1.1 CNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
16873489 31074 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 8 2.5 O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1cccc(-c2ccc3nncn3n2)c1 nan
CHEMBL1399932 31074 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 8 2.5 O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1cccc(-c2ccc3nncn3n2)c1 nan
20957244 31230 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 0 9 2.5 CCOc1ccc(N(C)C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1401299 31230 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 0 9 2.5 CCOc1ccc(N(C)C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
5053439 31245 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 6 1.2 COC(CNC(=O)c1ccc2nc3ccccc3c(=O)n2c1)OC nan
CHEMBL1401405 31245 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 6 1.2 COC(CNC(=O)c1ccc2nc3ccccc3c(=O)n2c1)OC nan
5734701 31442 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1 nan
CHEMBL1403145 31442 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1 nan
5302177 31528 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 0 5 2.0 O=c1nc2ccccn2c2ccc(S(=O)(=O)N3CCCCC3)cc12 nan
CHEMBL1404020 31528 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 0 5 2.0 O=c1nc2ccccn2c2ccc(S(=O)(=O)N3CCCCC3)cc12 nan
1504305 31731 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 5 0 7 1.7 Cc1cc(C)n(C(=O)CCCn2cc([N+](=O)[O-])cn2)n1 nan
CHEMBL1405977 31731 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 5 0 7 1.7 Cc1cc(C)n(C(=O)CCCn2cc([N+](=O)[O-])cn2)n1 nan
5221227 31961 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 10 -0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCN4CCOCC4)c3nc12 nan
CHEMBL1407863 31961 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 10 -0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCN4CCOCC4)c3nc12 nan
975666 32098 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 7 1.6 Cc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
CHEMBL1408899 32098 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 7 1.6 Cc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
3152548 32114 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1)c1ccco1 nan
CHEMBL1409014 32114 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1)c1ccco1 nan
3147984 32195 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 2.5 CCN(CC)C(=O)CSc1nnc2c3ccccc3n(C)c2n1 nan
CHEMBL1409671 32195 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 2.5 CCN(CC)C(=O)CSc1nnc2c3ccccc3n(C)c2n1 nan
2740105 32264 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 0 4 3.3 N#Cc1c(N2CCCC2)nsc1-c1ccccc1 nan
CHEMBL1410151 32264 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 0 4 3.3 N#Cc1c(N2CCCC2)nsc1-c1ccccc1 nan
2965406 32269 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 5 4.1 O=C(NCCCn1ccnc1)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1410223 32269 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 5 4.1 O=C(NCCCn1ccnc1)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
609181 32453 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 1 3 4.1 CC1(C(=O)Nc2nc3ccccc3s2)CC1(Br)Br nan
CHEMBL1411818 32453 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 1 3 4.1 CC1(C(=O)Nc2nc3ccccc3s2)CC1(Br)Br nan
2328662 32574 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 7 2.6 CCOC(=O)Cc1csc(-n2sc3ccccc3c2=O)n1 nan
CHEMBL1412731 32574 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 7 2.6 CCOC(=O)Cc1csc(-n2sc3ccccc3c2=O)n1 nan
716956 32815 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.5 COc1cc(-c2oc3ccc(C)cc3c(=O)c2O)cc(OC)c1OC nan
CHEMBL1414686 32815 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.5 COc1cc(-c2oc3ccc(C)cc3c(=O)c2O)cc(OC)c1OC nan
16019291 33158 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 4 5.2 Clc1cccc(CSc2ccc(-c3cccs3)nn2)c1 nan
CHEMBL1417757 33158 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 4 5.2 Clc1cccc(CSc2ccc(-c3cccs3)nn2)c1 nan
17581531 33180 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.5 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCCS3 nan
CHEMBL1417902 33180 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.5 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCCS3 nan
1505908 33381 11 None -21 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 1.5 Cc1c(F)cccc1NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C nan
CHEMBL1419634 33381 11 None -21 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 1.5 Cc1c(F)cccc1NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C nan
2138543 33668 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
CHEMBL1422079 33668 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
3937026 34231 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.5 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCC1 nan
CHEMBL1426645 34231 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.5 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCC1 nan
5909825 34874 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 1 9 2.5 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
CHEMBL1432124 34874 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 1 9 2.5 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
16011119 35154 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.2 Cc1ccc(CNC(=O)C(C)n2nc(C)n3c(cc4sccc43)c2=O)cc1 nan
CHEMBL1435058 35154 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.2 Cc1ccc(CNC(=O)C(C)n2nc(C)n3c(cc4sccc43)c2=O)cc1 nan
16018536 35280 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 5 5.2 O=C(NCc1cccs1)c1ccc2c(c1)sc1nc(-c3ccccc3)cn12 nan
CHEMBL1436706 35280 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 5 5.2 O=C(NCc1cccs1)c1ccc2c(c1)sc1nc(-c3ccccc3)cn12 nan
16011654 35286 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1ccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)cc1 nan
CHEMBL1436776 35286 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1ccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)cc1 nan
790330 35511 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2nc(C)cc(S)c2c1 nan
CHEMBL1439016 35511 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2nc(C)cc(S)c2c1 nan
22333977 35532 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)c(OC)c1 nan
CHEMBL1439223 35532 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)c(OC)c1 nan
974773 35697 8 None -19 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 1 2 2 2.9 O=C(O)c1ccc2cccc(Cl)c2c1O nan
CHEMBL1440675 35697 8 None -19 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 1 2 2 2.9 O=C(O)c1ccc2cccc(Cl)c2c1O nan
1048151 36194 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 3.8 COc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
CHEMBL1445229 36194 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 3.8 COc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
16407102 36200 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 8 1 9 2.8 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCN4CCOCC4)cc3c3ccnc2c31 nan
CHEMBL1445287 36200 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 8 1 9 2.8 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCN4CCOCC4)cc3c3ccnc2c31 nan
3244615 36609 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 8 1.2 O=C(Cn1cnc2sc3c(c2c1=O)CCCC3)NCCC(=O)N1CCC2(CC1)OCCO2 nan
CHEMBL1448799 36609 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 8 1.2 O=C(Cn1cnc2sc3c(c2c1=O)CCCC3)NCCC(=O)N1CCC2(CC1)OCCO2 nan
5333438 36710 10 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 3 5 0.9 O=C(O)/C=C\C(=O)Nc1cc(O)ccc1[N+](=O)[O-] nan
CHEMBL1449557 36710 10 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 3 5 0.9 O=C(O)/C=C\C(=O)Nc1cc(O)ccc1[N+](=O)[O-] nan
946874 37125 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 8 2.2 COC(=O)CSc1nc2ccccc2nc1SCC(=O)OC nan
CHEMBL1452913 37125 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 8 2.2 COC(=O)CSc1nc2ccccc2nc1SCC(=O)OC nan
15990397 37191 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 7 2.2 COc1cc(NC(=O)c2nc3ccccc3n(C)c2=O)cc(OC)c1OC nan
CHEMBL1453389 37191 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 7 2.2 COc1cc(NC(=O)c2nc3ccccc3n(C)c2=O)cc(OC)c1OC nan
2072948 37336 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 4 3.4 Brc1ccc2ncnc(NCc3cccnc3)c2c1 nan
CHEMBL1454562 37336 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 4 3.4 Brc1ccc2ncnc(NCc3cccnc3)c2c1 nan
20957239 37684 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 5 1 8 2.5 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1F nan
CHEMBL1457707 37684 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 5 1 8 2.5 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1F nan
8031083 37880 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 7 2.1 CCOC(=O)CCc1c(C)c2ccc3c(c2oc1=O)CN(CCCO)CO3 nan
CHEMBL1459326 37880 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 7 2.1 CCOC(=O)CCc1c(C)c2ccc3c(c2oc1=O)CN(CCCO)CO3 nan
1947745 38294 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
1947746 38294 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
CHEMBL1462881 38294 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
3593326 38316 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 8 1.1 CCOC(=O)C1=NN(c2ccc([N+](=O)[O-])cc2)CC1C(=O)OC nan
CHEMBL1463045 38316 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 8 1.1 CCOC(=O)C1=NN(c2ccc([N+](=O)[O-])cc2)CC1C(=O)OC nan
3889908 38400 15 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
663903 38400 15 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
CHEMBL1463781 38400 15 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
4834173 38622 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 6 2.7 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cccc(C#N)c2)c1 nan
CHEMBL1465419 38622 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 6 2.7 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cccc(C#N)c2)c1 nan
2124679 38712 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.7 O=C(COc1ncnc2ccc(Br)cc12)NCc1ccco1 nan
CHEMBL1466120 38712 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.7 O=C(COc1ncnc2ccc(Br)cc12)NCc1ccco1 nan
5840379 38848 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 4 1 9 0.8 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CC(C)OC(C)C3)nc12 nan
CHEMBL1467214 38848 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 4 1 9 0.8 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CC(C)OC(C)C3)nc12 nan
2824481 39000 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 5 3.9 N#Cc1c(N2CCSCC2)nsc1-c1ccccc1Cl nan
CHEMBL1468502 39000 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 5 3.9 N#Cc1c(N2CCSCC2)nsc1-c1ccccc1Cl nan
5911323 39124 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.0 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(C)cc2)cc1 nan
CHEMBL1469507 39124 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.0 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(C)cc2)cc1 nan
3186594 39305 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1471097 39305 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
5302637 39514 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 4 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2)cc1 nan
CHEMBL1473111 39514 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 4 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2)cc1 nan
16009440 39579 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 7 4.0 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1C nan
CHEMBL1474025 39579 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 7 4.0 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1C nan
16018838 39582 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 0 5 4.9 Clc1cccc(CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1474070 39582 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 0 5 4.9 Clc1cccc(CSc2nncn3c2cc2sccc23)c1 nan
16033266 39704 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.3 Cc1c(C(=O)NC(C)c2ccccc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1475712 39704 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.3 Cc1c(C(=O)NC(C)c2ccccc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
16030277 39708 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1 nan
CHEMBL1475778 39708 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1 nan
16018142 39731 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 6 1 2 4.0 Cn1cc(CCCC(=O)NCc2ccc(F)cc2)c2ccccc21 nan
CHEMBL1476187 39731 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 6 1 2 4.0 Cn1cc(CCCC(=O)NCc2ccc(F)cc2)c2ccccc21 nan
16018630 39739 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 4.0 O=C(CSc1nncn2c1cc1occc12)Nc1ccc(F)c(Cl)c1 nan
CHEMBL1476304 39739 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 4.0 O=C(CSc1nncn2c1cc1occc12)Nc1ccc(F)c(Cl)c1 nan
16018040 39752 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 6 3.1 COc1ccc(OC)c(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1476501 39752 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 6 3.1 COc1ccc(OC)c(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
135407487 39766 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(CNC(=O)CSc2nc3[nH]nc(C)c3c(=N)n2-c2ccccc2Cl)cc1 nan
CHEMBL1476621 39766 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(CNC(=O)CSc2nc3[nH]nc(C)c3c(=N)n2-c2ccccc2Cl)cc1 nan
676907 39865 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 205 1 1 3 2.8 COc1ccc2c(C)cc(S)nc2c1 nan
CHEMBL1477596 39865 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 205 1 1 3 2.8 COc1ccc2c(C)cc(S)nc2c1 nan
16018964 40103 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.2 CCC(C)NC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1479750 40103 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.2 CCC(C)NC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16018270 40599 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 5 5.5 CC(=O)Nc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
CHEMBL1484019 40599 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 5 5.5 CC(=O)Nc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
4613858 40995 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 1 2 7 0.9 COC(=O)c1sc2[nH]c(=S)n(N)c(=O)c2c1C nan
CHEMBL1487438 40995 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 1 2 7 0.9 COC(=O)c1sc2[nH]c(=S)n(N)c(=O)c2c1C nan
1173795 41144 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 1.9 CCCn1c(SCC(=O)Nc2ccc(NC(=O)CC)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1488482 41144 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 1.9 CCCn1c(SCC(=O)Nc2ccc(NC(=O)CC)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
3152454 41176 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 3 8 0.4 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1CCCO nan
CHEMBL1488709 41176 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 3 8 0.4 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1CCCO nan
1294912 41615 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 2 8 3.8 COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
CHEMBL1491898 41615 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 2 8 3.8 COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
3944710 41622 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 8 2.1 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cc(O)nc2ccccc12 nan
CHEMBL1491951 41622 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 8 2.1 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cc(O)nc2ccccc12 nan
2958357 41948 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 6 2.9 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCC3 nan
CHEMBL1494894 41948 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 6 2.9 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCC3 nan
3601528 41982 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 2 7 5.3 COc1ccc(C(=O)Nc2nc3n(n2)C(c2ccc(Cl)cc2)C=C(c2ccccc2)N3)cc1OC nan
CHEMBL1495241 41982 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 2 7 5.3 COc1ccc(C(=O)Nc2nc3n(n2)C(c2ccc(Cl)cc2)C=C(c2ccccc2)N3)cc1OC nan
3120647 41989 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 3 1 4 6.9 O=C(Nc1ccc2oc(-c3cc(Br)ccc3Cl)nc2c1)c1cc2ccccc2o1 nan
CHEMBL1495306 41989 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 3 1 4 6.9 O=C(Nc1ccc2oc(-c3cc(Br)ccc3Cl)nc2c1)c1cc2ccccc2o1 nan
3296097 42086 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 5 1 9 4.1 CCc1ccc(-n2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3nncc-3c2O)cc1 nan
CHEMBL1496299 42086 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 5 1 9 4.1 CCc1ccc(-n2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3nncc-3c2O)cc1 nan
2175955 42572 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3cccnc3)cc2)c1C nan
CHEMBL1500554 42572 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3cccnc3)cc2)c1C nan
2868511 42600 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 4 3.5 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(C)cc2)cc1 nan
CHEMBL1500746 42600 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 4 3.5 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(C)cc2)cc1 nan
3146565 42835 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 4.0 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1502935 42835 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 4.0 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
2998667 43007 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 9 -1.9 CC(=O)OCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1504458 43007 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 9 -1.9 CC(=O)OCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
2497236 43205 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 6 4.6 CCOc1ccc(-c2nc(-c3cccs3)c(CC(=O)O)s2)cc1OC nan
CHEMBL1506154 43205 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 6 4.6 CCOc1ccc(-c2nc(-c3cccs3)c(CC(=O)O)s2)cc1OC nan
1442564 43612 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 3.5 COC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
CHEMBL1509687 43612 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 3.5 COC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
6305743 43623 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 7 1 5 3.2 COCCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1509795 43623 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 7 1 5 3.2 COCCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
15988981 43906 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 8 2 7 4.1 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(=O)NCc3ccccc3Cl)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1512541 43906 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 8 2 7 4.1 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(=O)NCc3ccccc3Cl)c(=O)c3sccc32)c(C)c1 nan
1116224 44024 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.1 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(C(F)(F)F)c2)n(C)c1=O nan
CHEMBL1514415 44024 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.1 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(C(F)(F)F)c2)n(C)c1=O nan
16018038 44098 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 5 3.8 CSc1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
CHEMBL1515402 44098 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 5 3.8 CSc1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
16016056 44128 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 7 5.0 COc1ccccc1-c1noc(-c2ccc(NCCc3ccccc3)c([N+](=O)[O-])c2)n1 nan
CHEMBL1515947 44128 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 7 5.0 COc1ccccc1-c1noc(-c2ccc(NCCc3ccccc3)c([N+](=O)[O-])c2)n1 nan
5069160 44202 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
CHEMBL1516839 44202 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
5389765 44416 9 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 8 1 6 3.1 COCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
CHEMBL1518887 44416 9 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 8 1 6 3.1 COCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
1238913 44560 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 0 9 -1.1 Cn1c(=O)c2c(nc(SCC(=O)N3CCOCC3)n2C)n(C)c1=O nan
CHEMBL1520162 44560 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 0 9 -1.1 Cn1c(=O)c2c(nc(SCC(=O)N3CCOCC3)n2C)n(C)c1=O nan
2165182 44685 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 5 2.9 Cc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)o1 nan
CHEMBL1521212 44685 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 5 2.9 Cc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)o1 nan
3111808 44737 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1 nan
CHEMBL1521616 44737 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1 nan
20957509 44859 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1522776 44859 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
4126696 44874 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 5 5.9 COc1ccc(-n2cc(-c3ccccc3)nc2SCC(=O)Nc2ccccc2)cc1Cl nan
CHEMBL1522905 44874 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 5 5.9 COc1ccc(-n2cc(-c3ccccc3)nc2SCC(=O)Nc2ccccc2)cc1Cl nan
2561590 45233 6 None -3 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 0 8 4.1 Cc1cc(C(=O)CSc2nc3ccccc3c(=O)n2C)c(C)n1Cc1ccc2c(c1)OCO2 nan
CHEMBL1526230 45233 6 None -3 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 0 8 4.1 Cc1cc(C(=O)CSc2nc3ccccc3c(=O)n2C)c(C)n1Cc1ccc2c(c1)OCO2 nan
15991183 45384 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 1 4 6.8 O=C(Nc1cccc(-c2nc3ccccc3o2)c1)c1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1527553 45384 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 1 4 6.8 O=C(Nc1cccc(-c2nc3ccccc3o2)c1)c1ccc(-c2ccc(Br)cc2)o1 nan
16014288 45736 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 2 8 3.8 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3nc(SC(C)C)ncc3Cl)cc2)n1 nan
CHEMBL1530646 45736 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 2 8 3.8 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3nc(SC(C)C)ncc3Cl)cc2)n1 nan
6078364 45745 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)cc1 nan
CHEMBL1530717 45745 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)cc1 nan
950608 46131 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 1.5 N#C/C(=C\c1c(N2CCCCCC2)nc2ccccn2c1=O)C(N)=O nan
CHEMBL1534139 46131 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 1.5 N#C/C(=C\c1c(N2CCCCCC2)nc2ccccn2c1=O)C(N)=O nan
5310696 46145 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 10 1 6 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OCC(C)C)cc2C)C1c1cccnc1 nan
CHEMBL1534309 46145 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 10 1 6 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OCC(C)C)cc2C)C1c1cccnc1 nan
1856407 46381 20 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 1.1 CCOC(=O)N1CCN(c2nc3c(C)cccn3c(=O)c2C=O)CC1 nan
CHEMBL1536792 46381 20 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 1.1 CCOC(=O)N1CCN(c2nc3c(C)cccn3c(=O)c2C=O)CC1 nan
1442728 46436 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 4 4.3 CC(C)c1nc(SCC(=O)NC2CCCCC2)c2ccccc2n1 nan
CHEMBL1537182 46436 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 4 4.3 CC(C)c1nc(SCC(=O)NC2CCCCC2)c2ccccc2n1 nan
6165328 46681 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 6 4.3 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Cl)cc2)cc1 nan
CHEMBL1539268 46681 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 6 4.3 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Cl)cc2)cc1 nan
2944889 46877 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 10 1 7 5.1 CCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccco2)cc1OCC nan
CHEMBL1540923 46877 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 10 1 7 5.1 CCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccco2)cc1OCC nan
1867273 47355 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
CHEMBL1544770 47355 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
3600899 47386 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 9 4.3 O=c1cc(CSc2nc3nncc-3c(O)n2-c2ccc(Br)cc2)nc2ccc(Br)cn12 nan
CHEMBL1545051 47386 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 9 4.3 O=c1cc(CSc2nc3nncc-3c(O)n2-c2ccc(Br)cc2)nc2ccc(Br)cn12 nan
135514845 47585 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 8 2.7 CN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
CHEMBL1546713 47585 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 8 2.7 CN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
1442627 47792 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 2 6 3.1 CCCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
CHEMBL1548632 47792 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 2 6 3.1 CCCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
16016034 48172 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 1 7 4.1 COc1ccccc1-c1noc(-c2ccc(NC(C)C)c([N+](=O)[O-])c2)n1 nan
CHEMBL1552261 48172 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 1 7 4.1 COc1ccccc1-c1noc(-c2ccc(NC(C)C)c([N+](=O)[O-])c2)n1 nan
16017890 48189 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 1.5 COCCCNC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
CHEMBL1552564 48189 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 1.5 COCCCNC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
16023050 48190 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 3.1 CCNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)C1 nan
CHEMBL1552569 48190 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 3.1 CCNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)C1 nan
3260331 48247 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 3 4.6 O=C(Cn1cc(C(=O)C2CC2)c2ccccc21)Nc1ccc(Br)cc1 nan
CHEMBL1553312 48247 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 3 4.6 O=C(Cn1cc(C(=O)C2CC2)c2ccccc21)Nc1ccc(Br)cc1 nan
16030436 48322 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 2.9 CC(C)C(=O)Nc1ccccc1OCc1cc(=O)n2ccccc2n1 nan
CHEMBL1554451 48322 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 2.9 CC(C)C(=O)Nc1ccccc1OCc1cc(=O)n2ccccc2n1 nan
16016784 48380 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 5.4 CCOC(=O)C1CCCN(C(=O)c2[nH]c3ccccc3c2Sc2ccc(Cl)cc2)C1 nan
CHEMBL1555295 48380 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 5.4 CCOC(=O)C1CCCN(C(=O)c2[nH]c3ccccc3c2Sc2ccc(Cl)cc2)C1 nan
16196698 48403 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 7 1.9 Cc1cc2nnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)n2c2ccccc12 nan
CHEMBL1555603 48403 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 7 1.9 Cc1cc2nnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)n2c2ccccc12 nan
2869543 48572 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 3.9 CCOC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
CHEMBL1557161 48572 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 3.9 CCOC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
1272771 48612 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 6 5.4 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)cc4C)sc3n2)cc1OC nan
CHEMBL1557478 48612 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 6 5.4 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)cc4C)sc3n2)cc1OC nan
3239737 48749 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 7 1.4 Cc1nn(C(C)C(=O)NCC2CCCO2)c(=O)c2cc3occc3n12 nan
CHEMBL1558668 48749 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 7 1.4 Cc1nn(C(C)C(=O)NCC2CCCO2)c(=O)c2cc3occc3n12 nan
1503106 48940 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 5 3.1 Cc1cc(CNC(=O)COc2ccc([N+](=O)[O-])cc2)c2ccccc2n1 nan
CHEMBL1560348 48940 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 5 3.1 Cc1cc(CNC(=O)COc2ccc([N+](=O)[O-])cc2)c2ccccc2n1 nan
2456723 49225 6 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 2 8 3.7 CCOC(=O)c1cc(-c2ccccc2)sc1NC(=O)COC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 nan
CHEMBL1562996 49225 6 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 2 8 3.7 CCOC(=O)c1cc(-c2ccccc2)sc1NC(=O)COC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 nan
3221518 49334 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 8 1 5 3.8 CCCNC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1563919 49334 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 8 1 5 3.8 CCCNC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
2952819 49399 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.3 O=C(Cn1nc(-c2cccc([N+](=O)[O-])c2)c2ccccc2c1=O)NCC1CCCO1 nan
CHEMBL1564585 49399 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.3 O=C(Cn1nc(-c2cccc([N+](=O)[O-])c2)c2ccccc2c1=O)NCC1CCCO1 nan
2869470 49596 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 0 5 3.6 Cc1nnc(Oc2ccc([N+](=O)[O-])cc2)c2ccccc12 nan
CHEMBL1566109 49596 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 0 5 3.6 Cc1nnc(Oc2ccc([N+](=O)[O-])cc2)c2ccccc12 nan
16008434 49686 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 5 4.7 O=C(c1ccc(Cl)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCCO3 nan
CHEMBL1566810 49686 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 5 4.7 O=C(c1ccc(Cl)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCCO3 nan
1017457 49794 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 11 0.2 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC3CCCCC3)n2C)n(C)c1=O nan
CHEMBL1567667 49794 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 11 0.2 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC3CCCCC3)n2C)n(C)c1=O nan
2912191 49884 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 4.4 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)cc2)o1 nan
CHEMBL1568384 49884 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 4.4 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)cc2)o1 nan
665555 50181 8 None -1 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 5 4.9 Cc1nc(SCC(=O)Nc2ccc(C)c(F)c2)c2oc3ccccc3c2n1 nan
CHEMBL1570874 50181 8 None -1 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 5 4.9 Cc1nc(SCC(=O)Nc2ccc(C)c(F)c2)c2oc3ccccc3c2n1 nan
4333346 50380 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 4 4.3 COc1ccc(CCNC(=O)CSc2ccc3ccccc3c2)cc1OC nan
CHEMBL1572841 50380 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 4 4.3 COc1ccc(CCNC(=O)CSc2ccc3ccccc3c2)cc1OC nan
20957497 50586 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 10 2 7 2.1 Cc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1574892 50586 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 10 2 7 2.1 Cc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
1938572 50802 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 6 3.6 O=C(COc1ccccc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
CHEMBL1576963 50802 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 6 3.6 O=C(COc1ccccc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
1632391 50956 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 3 4 2.0 O=C(O)CCC(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
CHEMBL1578274 50956 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 3 4 2.0 O=C(O)CCC(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
3504887 51008 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 7 1.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC1 nan
CHEMBL1578618 51008 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 7 1.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC1 nan
20903631 51014 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 0 9 1.2 COc1cccc(N2CCN(c3ccc4nnc(CCC(=O)N5CCN(C)CC5)n4n3)CC2)c1 nan
CHEMBL1578662 51014 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 0 9 1.2 COc1cccc(N2CCN(c3ccc4nnc(CCC(=O)N5CCN(C)CC5)n4n3)CC2)c1 nan
16475 51657 43 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 4 4 1.9 Nc1ccc(-c2ccc(N)c(C(=O)O)c2)cc1C(=O)O nan
CHEMBL1584156 51657 43 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 4 4 1.9 Nc1ccc(-c2ccc(N)c(C(=O)O)c2)cc1C(=O)O nan
1997175 51704 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 0 7 0.9 CN1CCN(c2nc3ccccn3c(=O)c2C=C(C#N)C#N)CC1 nan
CHEMBL1584587 51704 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 0 7 0.9 CN1CCN(c2nc3ccccn3c(=O)c2C=C(C#N)C#N)CC1 nan
20881207 51948 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 10 1 8 2.5 CC(C)OCCCn1c(=O)c2ccccc2n2c(CCC(=O)NCc3ccccn3)nnc12 nan
CHEMBL1586569 51948 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 10 1 8 2.5 CC(C)OCCCn1c(=O)c2ccccc2n2c(CCC(=O)NCc3ccccn3)nnc12 nan
3186634 51949 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 0 9 -1.2 CN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
CHEMBL1586576 51949 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 0 9 -1.2 CN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
658021 52223 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 0 5 3.0 CSC1=NP(=S)(SC)N(C)c2nc3n(c21)CCC3 nan
CHEMBL1588879 52223 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 0 5 3.0 CSC1=NP(=S)(SC)N(C)c2nc3n(c21)CCC3 nan
7190667 52333 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1cccc(F)c1 nan
CHEMBL1589799 52333 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1cccc(F)c1 nan
16030609 52376 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 0 5 5.7 CCN(C(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1)c1cccc(C)c1 nan
CHEMBL1590288 52376 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 0 5 5.7 CCN(C(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1)c1cccc(C)c1 nan
6221827 52406 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.0 COc1ccc(CNC(=O)Cc2c(C)c3c(O)cc(C)cc3oc2=O)cc1 nan
CHEMBL1590750 52406 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.0 COc1ccc(CNC(=O)Cc2c(C)c3c(O)cc(C)cc3oc2=O)cc1 nan
16030275 52488 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 0 4 4.9 CCCCN(C)C(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
CHEMBL1591718 52488 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 0 4 4.9 CCCCN(C)C(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
16031876 52540 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 5 5.0 CCC1CCCCN1Cc1cn2c(-c3ccc(Br)cc3)nnc2s1 nan
CHEMBL1592401 52540 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 5 5.0 CCC1CCCCN1Cc1cn2c(-c3ccc(Br)cc3)nnc2s1 nan
5768121 52752 11 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 6 4.6 Cc1cc(OCC(C)C)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
CHEMBL1594882 52752 11 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 6 4.6 Cc1cc(OCC(C)C)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
4968658 52862 6 None -5 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3ccc(Cl)cc3)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1595841 52862 6 None -5 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3ccc(Cl)cc3)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
4875333 53487 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 4 3.5 CCn1c2ccccc2c2nc3cc(C(=O)O)ccc3nc21 nan
CHEMBL1601617 53487 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 4 3.5 CCn1c2ccccc2c2nc3cc(C(=O)O)ccc3nc21 nan
15988911 53804 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 0 7 4.2 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3c(C)cc(C)cc3C)c2=O)c1 nan
CHEMBL1604412 53804 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 0 7 4.2 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3c(C)cc(C)cc3C)c2=O)c1 nan
824096 53896 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 220 0 2 5 1.2 N=c1c2c3c(sc2ncn1N)CCCC3 nan
CHEMBL1605294 53896 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 220 0 2 5 1.2 N=c1c2c3c(sc2ncn1N)CCCC3 nan
16020886 53984 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 5 6.1 Cc1ccc(CSc2nc3cccnc3n2Cc2ccc(C(=O)NC3CCCCC3)cc2)cc1 nan
CHEMBL1605955 53984 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 5 6.1 Cc1ccc(CSc2nc3cccnc3n2Cc2ccc(C(=O)NC3CCCCC3)cc2)cc1 nan
3973561 54357 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 0 7 4.1 COc1ccc2cc(C(=O)COC(=O)COc3ccc4c(C)cc(=O)oc4c3)ccc2c1 nan
CHEMBL1608925 54357 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 0 7 4.1 COc1ccc2cc(C(=O)COC(=O)COc3ccc4c(C)cc(=O)oc4c3)ccc2c1 nan
4916122 54476 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 6 1.7 Cc1cccc(NC(=O)C(C)n2cc([N+](=O)[O-])cn2)n1 nan
CHEMBL1609905 54476 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 6 1.7 Cc1cccc(NC(=O)C(C)n2cc([N+](=O)[O-])cn2)n1 nan
3151454 54661 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 2 8 1.4 COCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
CHEMBL1611459 54661 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 2 8 1.4 COCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
2810155 54852 6 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 5 3.6 Cc1ccccc1C(=O)Nc1nc2c(C)csc2c(=O)s1 nan
CHEMBL1613272 54852 6 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 5 3.6 Cc1ccccc1C(=O)Nc1nc2c(C)csc2c(=O)s1 nan
6489921 55320 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 0 2 3.4 CCCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
CHEMBL1384004 55320 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 0 2 3.4 CCCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
CHEMBL1618913 55320 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 0 2 3.4 CCCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
135415554 55751 3 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 7 4.4 Cc1nn(CCc2nc(-c3ccco3)cs2)c2nc(O)cc(C(F)(F)F)c12 nan
CHEMBL1494334 55751 3 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 7 4.4 Cc1nn(CCc2nc(-c3ccco3)cs2)c2nc(O)cc(C(F)(F)F)c12 nan
CHEMBL1622628 55751 3 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 7 4.4 Cc1nn(CCc2nc(-c3ccco3)cs2)c2nc(O)cc(C(F)(F)F)c12 nan
24792259 55811 1 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 3 6 2.5 Nc1c(S(=O)(=O)O)cc(NC(=O)c2ccccc2)c2c1C(=O)c1ccccc1C2=O nan
CHEMBL1517470 55811 1 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 3 6 2.5 Nc1c(S(=O)(=O)O)cc(NC(=O)c2ccccc2)c2c1C(=O)c1ccccc1C2=O nan
CHEMBL1623157 55811 1 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 3 6 2.5 Nc1c(S(=O)(=O)O)cc(NC(=O)c2ccccc2)c2c1C(=O)c1ccccc1C2=O nan
4323731 107670 4 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 3 3 4 5.9 Oc1c(Br)cc(/C=N/c2ccc3[nH]c(-c4ccccc4)nc3c2)c(O)c1Br nan
CHEMBL3190756 107670 4 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 3 3 4 5.9 Oc1c(Br)cc(/C=N/c2ccc3[nH]c(-c4ccccc4)nc3c2)c(O)c1Br nan
4073001 108687 10 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 0 8 2.6 COC(=O)Cn1/c(=N/C(=O)c2ccc(OC)c(OC)c2)sc2cc(OC)ccc21 nan
CHEMBL3208346 108687 10 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 0 8 2.6 COC(=O)Cn1/c(=N/C(=O)c2ccc(OC)c(OC)c2)sc2cc(OC)ccc21 nan
6870745 109069 10 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 0 7 2.1 Cc1nc2ccccc2c(=O)n1/N=C/c1ccc([N+](=O)[O-])o1 nan
CHEMBL3213340 109069 10 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 0 7 2.1 Cc1nc2ccccc2c(=O)n1/N=C/c1ccc([N+](=O)[O-])o1 nan
2941245 146824 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.8 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccccc3)C2c2cccnc2)o1 nan
CHEMBL392515 146824 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.8 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccccc3)C2c2cccnc2)o1 nan
1016096 191771 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 6 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
CHEMBL519824 191771 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 6 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
726062 197016 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 0 2 5 2.6 Oc1nc(S)nc2sc3c(c12)CCCC3 nan
CHEMBL1583656 197016 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 0 2 5 2.6 Oc1nc(S)nc2sc3c(c12)CCCC3 nan
CHEMBL567206 197016 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 0 2 5 2.6 Oc1nc(S)nc2sc3c(c12)CCCC3 nan
2998030 31488 6 None - 1 Human 5.7 pPotency = 5.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 3 6 0.5 COCCNC(=O)NC(=O)COC(=O)C12CC3CC(CC(NC(C)=O)(C3)C1)C2 nan
CHEMBL1403647 31488 6 None - 1 Human 5.7 pPotency = 5.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 3 6 0.5 COCCNC(=O)NC(=O)COC(=O)C12CC3CC(CC(NC(C)=O)(C3)C1)C2 nan
975392 42441 9 None -1 2 Human 5.7 pPotency = 5.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 1 1 2 4.3 Cc1cc(Br)c2nc3c(c(C(=O)O)c2c1)CCCCC3 nan
CHEMBL1499411 42441 9 None -1 2 Human 5.7 pPotency = 5.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 1 1 2 4.3 Cc1cc(Br)c2nc3c(c(C(=O)O)c2c1)CCCCC3 nan
16019550 10675 14 None -131 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 8 4.3 O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCCC1)c1sccc12 nan
CHEMBL1170886 10675 14 None -131 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 8 4.3 O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCCC1)c1sccc12 nan
4204374 19541 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 6 2 6 3.4 COc1cc2nc(S)nc(NCCC(C)C)c2cc1OC nan
CHEMBL1299978 19541 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 6 2 6 3.4 COc1cc2nc(S)nc(NCCC(C)C)c2cc1OC nan
2421557 19690 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 0 7 3.6 COC(=O)CCc1c(C)c(C(=O)c2cc(OC)c(OC)c(OC)c2)c2ccccn12 nan
CHEMBL1301080 19690 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 0 7 3.6 COC(=O)CCc1c(C)c(C(=O)c2cc(OC)c(OC)c(OC)c2)c2ccccn12 nan
22548258 20261 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 6 1.7 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1 nan
CHEMBL1305765 20261 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 6 1.7 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1 nan
16194269 20450 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 560 7 1 8 2.4 O=C(CSC1=Nc2ccccc2C2=NC(CC(=O)N3CCN(c4ccccc4)CC3)C(=O)N12)NCC1CCCO1 nan
CHEMBL1307199 20450 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 560 7 1 8 2.4 O=C(CSC1=Nc2ccccc2C2=NC(CC(=O)N3CCN(c4ccccc4)CC3)C(=O)N12)NCC1CCCO1 nan
3740686 21078 14 None -7 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)no1 nan
CHEMBL1312274 21078 14 None -7 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)no1 nan
4465171 21226 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 6 3.1 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCCC2)c1 nan
CHEMBL1313361 21226 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 6 3.1 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCCC2)c1 nan
2197541 21277 10 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.3 CC(C)c1ccc(-c2c(C#N)c(N)nc(SCC(=O)N3CCCCC3)c2C#N)cc1 nan
CHEMBL1313695 21277 10 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.3 CC(C)c1ccc(-c2c(C#N)c(N)nc(SCC(=O)N3CCCCC3)c2C#N)cc1 nan
2679228 21332 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 7 4.0 COc1ccc2oc(C(=O)Nc3nc4ccc(S(C)(=O)=O)cc4s3)c(C)c2c1 nan
CHEMBL1314240 21332 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 7 4.0 COc1ccc2oc(C(=O)Nc3nc4ccc(S(C)(=O)=O)cc4s3)c(C)c2c1 nan
16034516 21364 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 6 4.6 Cc1nnc(SCC(=O)NCc2ccccc2F)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
CHEMBL1314574 21364 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 6 4.6 Cc1nnc(SCC(=O)NCc2ccccc2F)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
135419125 21395 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 1 3 5.7 Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(c2ccccc2)C1 nan
CHEMBL1315137 21395 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 1 3 5.7 Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(c2ccccc2)C1 nan
16012610 21402 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 4 0 10 4.0 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccc(Cl)cc5)s4)c3nc12 nan
CHEMBL1315199 21402 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 4 0 10 4.0 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccc(Cl)cc5)s4)c3nc12 nan
4119285 21449 13 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
CHEMBL1315733 21449 13 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
24892214 21465 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 1 8 2.2 COc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
CHEMBL1315929 21465 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 1 8 2.2 COc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
7599144 21473 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 5 3.1 Cc1cc(NC(=O)c2cccn(Cc3cccc(Cl)c3)c2=O)no1 nan
CHEMBL1315995 21473 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 5 3.1 Cc1cc(NC(=O)c2cccn(Cc3cccc(Cl)c3)c2=O)no1 nan
16018244 21637 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3ccccc3Cl)cc1CC2 nan
CHEMBL1318247 21637 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3ccccc3Cl)cc1CC2 nan
15944876 21758 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 5 4.1 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1319259 21758 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 5 4.1 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)cc1 nan
16010992 21842 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 1 8 2.6 CCc1cc2c(cc3c(=O)n(CC(=O)NCCc4ccc(OC)c(OC)c4)ncn32)s1 nan
CHEMBL1319991 21842 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 1 8 2.6 CCc1cc2c(cc3c(=O)n(CC(=O)NCCc4ccc(OC)c(OC)c4)ncn32)s1 nan
4164390 21929 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 1 5 6.1 CC(C)OC(=O)c1c(NC(=O)C2c3ccccc3Oc3ccccc32)sc2c1CCCC2 nan
CHEMBL1320657 21929 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 1 5 6.1 CC(C)OC(=O)c1c(NC(=O)C2c3ccccc3Oc3ccccc32)sc2c1CCCC2 nan
25102515 21951 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 4 4.1 Cc1cc(=O)oc2cc(NC(=O)COc3cccc(C(F)(F)F)c3)ccc12 nan
CHEMBL1320916 21951 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 4 4.1 Cc1cc(=O)oc2cc(NC(=O)COc3cccc(C(F)(F)F)c3)ccc12 nan
794839 22006 34 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 1 1 4 2.8 Sc1nnc(-c2cccc(Br)c2)o1 nan
CHEMBL1321356 22006 34 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 1 1 4 2.8 Sc1nnc(-c2cccc(Br)c2)o1 nan
16018780 22008 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4cccc(Cl)c4)nnc(C)n32)o1 nan
CHEMBL1321426 22008 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4cccc(Cl)c4)nnc(C)n32)o1 nan
3996443 22058 6 None -7 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 1 10 -0.7 Cn1c(N)c(C(=O)COC(=O)COc2ccccc2C#N)c(=O)n(C)c1=O nan
CHEMBL1321877 22058 6 None -7 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 1 10 -0.7 Cn1c(N)c(C(=O)COC(=O)COc2ccccc2C#N)c(=O)n(C)c1=O nan
16009867 22300 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 7 4.5 CCOc1ccccc1NC(=O)Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sc3ccccc3c21 nan
CHEMBL1324000 22300 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 7 4.5 CCOc1ccccc1NC(=O)Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sc3ccccc3c21 nan
1442375 22406 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 4 4.1 CC(C)(C)c1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1324849 22406 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 4 4.1 CC(C)(C)c1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
22517548 22521 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 1 7 1.6 O=C(Nc1nnc(S(=O)(=O)N2CCOCC2)s1)c1ccccc1Br nan
CHEMBL1326013 22521 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 1 7 1.6 O=C(Nc1nnc(S(=O)(=O)N2CCOCC2)s1)c1ccccc1Br nan
20927538 22635 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 0 7 1.3 CN(Cc1ccco1)C(=O)Cn1cc(S(=O)(=O)N2CCCC2)c(S(=O)(=O)N2CCCC2)c1 nan
CHEMBL1327078 22635 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 0 7 1.3 CN(Cc1ccco1)C(=O)Cn1cc(S(=O)(=O)N2CCCC2)c(S(=O)(=O)N2CCCC2)c1 nan
2645777 22730 15 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 1 3 4.4 N#Cc1c(S)nc(-c2ccccc2Cl)c2c1CCCC2 nan
CHEMBL1327817 22730 15 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 1 3 4.4 N#Cc1c(S)nc(-c2ccccc2Cl)c2c1CCCC2 nan
2816375 22958 28 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 2 1 7 1.7 CCOC(=O)c1nnn2c1nc(S)c1ccccc12 nan
CHEMBL1329724 22958 28 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 2 1 7 1.7 CCOC(=O)c1nnn2c1nc(S)c1ccccc12 nan
3151322 22967 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 7 2.0 N=c1c(C(=O)NC2CCCC2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
CHEMBL1329807 22967 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 7 2.0 N=c1c(C(=O)NC2CCCC2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
16030826 23116 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 2 5 2.9 NC(=O)C1CCN(C(=O)c2ccccc2NC(=O)c2nsc3ccccc23)CC1 nan
CHEMBL1330985 23116 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 2 5 2.9 NC(=O)C1CCN(C(=O)c2ccccc2NC(=O)c2nsc3ccccc23)CC1 nan
2815453 23355 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 0 0 5 0.3 Cn1c2c(c(=O)n3ncnc13)CCCC2 nan
CHEMBL1332830 23355 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 0 0 5 0.3 Cn1c2c(c(=O)n3ncnc13)CCCC2 nan
16019110 23364 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 3.3 O=C(Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21)Nc1ccccc1 nan
CHEMBL1332893 23364 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 3.3 O=C(Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21)Nc1ccccc1 nan
16018748 23367 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 0 5 4.7 Cc1nnc(SCc2ccc(Cl)cc2)c2cc3occc3n12 nan
CHEMBL1332908 23367 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 0 5 4.7 Cc1nnc(SCc2ccc(Cl)cc2)c2cc3occc3n12 nan
876371 23431 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 4 2.2 Cc1cc(/C=C2/C(=O)NC(=O)N(C)C2=O)c(C)n1-c1ccccc1 nan
CHEMBL1333432 23431 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 4 2.2 Cc1cc(/C=C2/C(=O)NC(=O)N(C)C2=O)c(C)n1-c1ccccc1 nan
16031513 23837 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 6 5.0 COc1ccc(-c2nnc(SCC(=O)Nc3cccc(C(F)(F)F)c3)s2)cc1 nan
CHEMBL1336578 23837 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 6 5.0 COc1ccc(-c2nnc(SCC(=O)Nc3cccc(C(F)(F)F)c3)s2)cc1 nan
16011266 24019 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 3.5 Cc1cccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)c1 nan
CHEMBL1338231 24019 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 3.5 Cc1cccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)c1 nan
16009346 24093 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 4 5.1 CCc1ccc2c(c1)c(=O)c(C(=O)c1ccc(C)cc1)cn2CC(=O)Nc1ccccc1C nan
CHEMBL1338819 24093 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 4 5.1 CCc1ccc2c(c1)c(=O)c(C(=O)c1ccc(C)cc1)cn2CC(=O)Nc1ccccc1C nan
1451340 24212 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 7 1 7 4.2 Cc1nonc1NC(=O)CSc1nc(CCC2CCCC2)nc2ccccc12 nan
CHEMBL1339937 24212 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 7 1 7 4.2 Cc1nonc1NC(=O)CSc1nc(CCC2CCCC2)nc2ccccc12 nan
1173483 24422 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 7 4.1 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1nc(C)c(C)s1)OCO3 nan
CHEMBL1341833 24422 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 7 4.1 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1nc(C)c(C)s1)OCO3 nan
3208214 24692 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 4.4 CCc1cc2cc(C)cc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1344061 24692 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 4.4 CCc1cc2cc(C)cc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
1442646 24880 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 4 4.3 CCCc1nc(SCC(=O)N2CCc3ccccc3C2)c2ccccc2n1 nan
CHEMBL1345722 24880 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 4 4.3 CCCc1nc(SCC(=O)N2CCc3ccccc3C2)c2ccccc2n1 nan
2322587 24900 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 9 1 6 1.7 CCN(CC)S(=O)(=O)c1ccc(C(=O)OCCNC(=O)c2cccnc2)cc1 nan
CHEMBL1345885 24900 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 9 1 6 1.7 CCN(CC)S(=O)(=O)c1ccc(C(=O)OCCNC(=O)c2cccnc2)cc1 nan
3475758 24920 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 7 1 9 4.5 COc1cc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc(OC)c1OC nan
CHEMBL1346015 24920 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 7 1 9 4.5 COc1cc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc(OC)c1OC nan
911360 24963 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 0 1 4 1.3 Cn1c(O)nc2c(Cl)nccc21 nan
CHEMBL1346457 24963 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 0 1 4 1.3 Cn1c(O)nc2c(Cl)nccc21 nan
745324 25017 8 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 3 5 4.4 Cc1ccc(NC(S)=Nc2cccc(-c3nnc(S)o3)c2)cc1 nan
CHEMBL1346824 25017 8 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 3 5 4.4 Cc1ccc(NC(S)=Nc2cccc(-c3nnc(S)o3)c2)cc1 nan
664458 25058 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 4 0 6 4.4 O=C(CSc1ncnc2c1oc1ccccc12)c1cccs1 nan
CHEMBL1347130 25058 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 4 0 6 4.4 O=C(CSc1ncnc2c1oc1ccccc12)c1cccs1 nan
866600 25094 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 0 6 1.7 CCN1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1347433 25094 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 0 6 1.7 CCN1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
2158422 25259 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 3 0 7 2.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)CC1 nan
CHEMBL1348934 25259 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 3 0 7 2.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)CC1 nan
7711373 25295 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 2.9 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccco1 nan
CHEMBL1349179 25295 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 2.9 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccco1 nan
20920345 25642 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1352171 25642 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
3742858 25853 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Br)cc2)no1 nan
CHEMBL1353643 25853 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Br)cc2)no1 nan
16009768 25982 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 9 2 6 5.1 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)COc2cccc(OC)c2)cc1 nan
CHEMBL1354836 25982 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 9 2 6 5.1 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)COc2cccc(OC)c2)cc1 nan
16022445 25989 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 1 3 4.8 CC1Cn2c(C(=O)NCc3cccc(Br)c3)cc3cccc(c32)S1 nan
CHEMBL1354873 25989 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 1 3 4.8 CC1Cn2c(C(=O)NCc3cccc(Br)c3)cc3cccc(c32)S1 nan
16024821 26063 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 1 4 5.2 O=C(Nc1ccc(Cl)cc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1355809 26063 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 1 4 5.2 O=C(Nc1ccc(Cl)cc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
5292880 26073 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 4 6.5 COc1cc(/C=C(\C#N)c2nc3ccccc3[nH]2)cc(Cl)c1OCc1ccccc1Cl nan
CHEMBL1355927 26073 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 4 6.5 COc1cc(/C=C(\C#N)c2nc3ccccc3[nH]2)cc(Cl)c1OCc1ccccc1Cl nan
7878585 26077 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 7 1.9 O=C(CNC(=O)c1ccc(Cl)cc1)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1356005 26077 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 7 1.9 O=C(CNC(=O)c1ccc(Cl)cc1)OCc1cc(=O)n2ccsc2n1 nan
6200344 26149 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 7 1 6 2.7 COc1cccc(/C=C/c2nc(C#N)c(NCCN(C)C)o2)c1 nan
CHEMBL1356982 26149 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 7 1 6 2.7 COc1cccc(/C=C/c2nc(C#N)c(NCCN(C)C)o2)c1 nan
1004107 26337 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 2 5 5.3 CCOc1cccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)c1 nan
CHEMBL1359199 26337 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 2 5 5.3 CCOc1cccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)c1 nan
16009637 26640 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 6 4.5 O=C(Nc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)cc1)c1ccccc1 nan
CHEMBL1361843 26640 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 6 4.5 O=C(Nc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)cc1)c1ccccc1 nan
4114478 26992 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 5.1 COc1cccc(NC(=O)Cn2cc(C(=O)C3CCCCC3)c3ccccc32)c1 nan
CHEMBL1364874 26992 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 5.1 COc1cccc(NC(=O)Cn2cc(C(=O)C3CCCCC3)c3ccccc32)c1 nan
22641 27241 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 7 0.8 CC(=O)OCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(C)cc21 nan
CHEMBL1367036 27241 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 7 0.8 CC(=O)OCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(C)cc21 nan
2378240 27346 29 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 2 1 4 2.7 Fc1ccccc1-c1nnc(S)n1C1CC1 nan
CHEMBL1367871 27346 29 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 2 1 4 2.7 Fc1ccccc1-c1nnc(S)n1C1CC1 nan
12006141 27674 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 4 4.8 Cc1ccc(CSc2ccc(-c3cccs3)nn2)cc1 nan
CHEMBL1370265 27674 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 4 4.8 Cc1ccc(CSc2ccc(-c3cccs3)nn2)cc1 nan
16455091 27786 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 2 8 3.0 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccc(F)cc4)ccc3=O)cc2)c1C nan
CHEMBL1371016 27786 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 2 8 3.0 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccc(F)cc4)ccc3=O)cc2)c1C nan
135406328 27985 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 1 7 1.3 Cc1cc(C)c2c(O)nc(SCC(=O)N3CCOCC3)nc2n1 nan
CHEMBL1372508 27985 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 1 7 1.3 Cc1cc(C)c2c(O)nc(SCC(=O)N3CCOCC3)nc2n1 nan
2138011 28367 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.1 COc1ccc(S(=O)(=O)c2cn(CC(=O)Nc3cc(C)ccc3C)c3ccccc3c2=O)cc1 nan
CHEMBL1375055 28367 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.1 COc1ccc(S(=O)(=O)c2cn(CC(=O)Nc3cc(C)ccc3C)c3ccccc3c2=O)cc1 nan
3571741 28372 12 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 4 4.6 Cc1ccc(-c2cc(C(=O)NCc3cnn(C)c3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1375116 28372 12 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 4 4.6 Cc1ccc(-c2cc(C(=O)NCc3cnn(C)c3)c3cc(Br)ccc3n2)cc1 nan
16025702 28403 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 6 5.9 CCOc1ccccc1CNC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1 nan
CHEMBL1375311 28403 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 6 5.9 CCOc1ccccc1CNC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1 nan
2874807 28893 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 1 7 4.6 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccc(C)cc3c2=O)C2=C(O)CCCC2=N1 nan
CHEMBL1379763 28893 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 1 7 4.6 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccc(C)cc3c2=O)C2=C(O)CCCC2=N1 nan
1564382 29073 11 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 7 1 7 5.8 CCCCn1c(NC(=O)c2ccc(Br)o2)c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc21 nan
CHEMBL1381243 29073 11 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 7 1 7 5.8 CCCCn1c(NC(=O)c2ccc(Br)o2)c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc21 nan
666048 29277 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 0 9 2.0 c1cncc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)c1 nan
CHEMBL1383055 29277 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 0 9 2.0 c1cncc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)c1 nan
220464 29279 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 175 0 0 2 2.9 Cn1ccc(=S)c2ccccc21 nan
CHEMBL1383064 29279 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 175 0 0 2 2.9 Cn1ccc(=S)c2ccccc21 nan
4805097 29292 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 2 0 7 0.4 CC1Cc2ccccc2N1C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1383239 29292 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 2 0 7 0.4 CC1Cc2ccccc2N1C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
1186390 29513 12 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 1 0 3 4.7 O=C(Oc1c(Br)cc(Br)c2cccnc12)N1CCCCC1 nan
CHEMBL1385192 29513 12 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 1 0 3 4.7 O=C(Oc1c(Br)cc(Br)c2cccnc12)N1CCCCC1 nan
4877595 29716 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 5 3.8 O=C(CSc1nnc(-c2ccc(F)cc2)c2ccccc12)NCC1CCCO1 nan
CHEMBL1386797 29716 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 5 3.8 O=C(CSc1nnc(-c2ccc(F)cc2)c2ccccc12)NCC1CCCO1 nan
865072 29973 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 4.0 CCOC(=O)CSc1nc(-c2ccccc2)nc2ccccc12 nan
CHEMBL1388860 29973 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 4.0 CCOC(=O)CSc1nc(-c2ccccc2)nc2ccccc12 nan
2406693 29996 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 8 2.5 COC(=O)c1sc2nc(C)nc(SCC(=O)N3CCC(C(=O)O)CC3)c2c1C nan
CHEMBL1389013 29996 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 8 2.5 COC(=O)c1sc2nc(C)nc(SCC(=O)N3CCC(C(=O)O)CC3)c2c1C nan
1261479 30143 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 2 5 3.5 Cc1cc(C)c2nc(-c3ccccn3)cc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c2c1 nan
CHEMBL1390223 30143 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 2 5 3.5 Cc1cc(C)c2nc(-c3ccccn3)cc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c2c1 nan
16033258 30592 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 5 5.2 Cc1c(C(=O)Nc2ccccc2F)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1394084 30592 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 5 5.2 Cc1c(C(=O)Nc2ccccc2F)sc2ncnc(N(C)C3CCCCC3)c12 nan
16019740 30594 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 8 2.9 CCn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
CHEMBL1394098 30594 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 8 2.9 CCn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
16019075 30622 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 6 4.4 CC(C)Oc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1394443 30622 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 6 4.4 CC(C)Oc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
1179391 30784 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 5 3.6 Cc1ccc(C(=O)Nc2nc3ccc(S(=O)(=O)N4CCCC4)cc3s2)cc1 nan
CHEMBL1396599 30784 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 5 3.6 Cc1ccc(C(=O)Nc2nc3ccc(S(=O)(=O)N4CCCC4)cc3s2)cc1 nan
16031181 30850 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.3 COc1cc(NC(=O)c2cc3cc4cc(OC)ccc4nc3o2)cc(OC)c1 nan
CHEMBL1397472 30850 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.3 COc1cc(NC(=O)c2cc3cc4cc(OC)ccc4nc3o2)cc(OC)c1 nan
16028170 30888 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 3 2 3 4.2 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(Cl)c3)cc21 nan
CHEMBL1397995 30888 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 3 2 3 4.2 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(Cl)c3)cc21 nan
729756 30911 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 1 3 3.9 Cc1ccc(/C=C(\C#N)C(=O)Nc2ccc(Br)cc2)o1 nan
CHEMBL1398350 30911 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 1 3 3.9 Cc1ccc(/C=C(\C#N)C(=O)Nc2ccc(Br)cc2)o1 nan
16031340 30918 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 3 4.7 CCc1ccc(CNC(=O)c2cnc(N3CCCCC3)c3ccccc23)cc1 nan
CHEMBL1398430 30918 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 3 4.7 CCc1ccc(CNC(=O)c2cnc(N3CCCCC3)c3ccccc23)cc1 nan
15989002 30919 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 1 8 2.8 O=C(CCn1c(=O)c2sccc2n(Cc2cccc(F)c2)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1398440 30919 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 1 8 2.8 O=C(CCn1c(=O)c2sccc2n(Cc2cccc(F)c2)c1=O)NCc1ccc2c(c1)OCO2 nan
16026774 30922 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 7 2.2 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3Cl)cc(=O)n12 nan
CHEMBL1398452 30922 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 7 2.2 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3Cl)cc(=O)n12 nan
24790947 31213 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 5 3.9 O=S(=O)(c1ccc2nc(N3CCN(c4ccc(F)cc4)CC3)ccc2c1)N1CCCCC1 nan
CHEMBL1401193 31213 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 5 3.9 O=S(=O)(c1ccc2nc(N3CCN(c4ccc(F)cc4)CC3)ccc2c1)N1CCCCC1 nan
16017881 31493 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 6 2.3 CCOc1ccc(NC(=O)Cn2ccn(-c3ccc(F)c(F)c3)c(=O)c2=O)cc1 nan
CHEMBL1403689 31493 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 6 2.3 CCOc1ccc(NC(=O)Cn2ccn(-c3ccc(F)c(F)c3)c(=O)c2=O)cc1 nan
654955 31759 5 None -4 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 4.7 CS(=O)(=O)c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N nan
CHEMBL1406204 31759 5 None -4 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 4.7 CS(=O)(=O)c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N nan
135416200 31761 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.9 CCN(CC)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
45369539 31761 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.9 CCN(CC)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
CHEMBL1406220 31761 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.9 CCN(CC)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
16025790 31811 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 4 4.5 CCC(C)NC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1406711 31811 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 4 4.5 CCC(C)NC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
1257542 31879 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 6 1.4 Cc1cccnc1NC(=O)Cn1nc([N+](=O)[O-])cc1C nan
CHEMBL1407331 31879 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 6 1.4 Cc1cccnc1NC(=O)Cn1nc([N+](=O)[O-])cc1C nan
5834534 31935 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 1 5 5.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(Cl)cc2)c(C)c1 nan
CHEMBL1407665 31935 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 1 5 5.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(Cl)cc2)c(C)c1 nan
1509257 31956 12 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 2 1 5 3.5 CCN1CCc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2C1 nan
CHEMBL1407777 31956 12 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 2 1 5 3.5 CCN1CCc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2C1 nan
981045 32148 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 0 9 -0.1 CCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1409260 32148 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 0 9 -0.1 CCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
2649456 32257 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 2 0 5 2.7 O=c1ccc(C(F)(F)F)cn1Cc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1410109 32257 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 2 0 5 2.7 O=c1ccc(C(F)(F)F)cn1Cc1cc(=O)n2cc(Br)ccc2n1 nan
1191742 32280 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 5 4.3 O=C(O)CSc1ncnc2scc(-c3ccc(Br)cc3)c12 nan
CHEMBL1410306 32280 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 5 4.3 O=C(O)CSc1ncnc2scc(-c3ccc(Br)cc3)c12 nan
15990415 32494 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 1 5 5.5 COc1ccc(Cl)cc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1412135 32494 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 1 5 5.5 COc1ccc(Cl)cc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
3151320 32528 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.4 N=c1c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
CHEMBL1412407 32528 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.4 N=c1c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
1484210 32533 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 0 5 3.6 CCSc1nnc(-c2ccccc2SC)o1 nan
CHEMBL1412417 32533 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 0 5 3.6 CCSc1nnc(-c2ccccc2SC)o1 nan
4433827 33039 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 2.8 CSc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CN(C)CC3 nan
CHEMBL1416667 33039 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 2.8 CSc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CN(C)CC3 nan
3245881 33585 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 9 2.6 COc1cc2nc(S)n3nc(CCn4nc(C)cc4C)nc3c2cc1OC nan
CHEMBL1421316 33585 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 9 2.6 COc1cc2nc(S)n3nc(CCn4nc(C)cc4C)nc3c2cc1OC nan
5102370 33881 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 9 1 5 1.7 CCN(CC)S(=O)(=O)c1cccc(C(=O)NCCCn2ccnc2)c1 nan
CHEMBL1423739 33881 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 9 1 5 1.7 CCN(CC)S(=O)(=O)c1cccc(C(=O)NCCCn2ccnc2)c1 nan
4872167 34108 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 7 5.2 CCCCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1425797 34108 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 7 5.2 CCCCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
2968003 34163 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 5 1 5 3.3 COc1ccc(-c2cc3ccc(OC(C)C(=O)O)cc3oc2=O)cc1 nan
CHEMBL1426170 34163 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 5 1 5 3.3 COc1ccc(-c2cc3ccc(OC(C)C(=O)O)cc3oc2=O)cc1 nan
5933014 34775 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 10 2 6 2.7 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2ccccc2)cc1 nan
CHEMBL1431128 34775 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 10 2 6 2.7 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2ccccc2)cc1 nan
2365417 34796 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 1 6 5.2 Cc1ccc2nc(-c3ccc(NC(=O)COC(=O)c4cncc(Br)c4)cc3)sc2c1 nan
CHEMBL1431340 34796 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 1 6 5.2 Cc1ccc2nc(-c3ccc(NC(=O)COC(=O)c4cncc(Br)c4)cc3)sc2c1 nan
2317063 34991 7 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 2 5 5.6 CCCCOc1ccc(-c2c(C#N)c(S)nc(C)c2C(=O)Nc2ccccc2)cc1 nan
CHEMBL1433074 34991 7 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 2 5 5.6 CCCCOc1ccc(-c2c(C#N)c(S)nc(C)c2C(=O)Nc2ccccc2)cc1 nan
16016637 35045 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 6 1 5 5.0 CCOc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2-n2cccc2)cc1 nan
CHEMBL1433449 35045 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 6 1 5 5.0 CCOc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2-n2cccc2)cc1 nan
16012551 35092 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 5 5.5 CCOc1ccc(-c2cc(NC(=O)c3cccc(Cl)c3)c(C(=O)OC)s2)cc1 nan
CHEMBL1434218 35092 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 5 5.5 CCOc1ccc(-c2cc(NC(=O)c3cccc(Cl)c3)c(C(=O)OC)s2)cc1 nan
16033555 35141 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 2 0 4 4.8 Cc1nc(Oc2ccccc2C)c2oc3ccccc3c2n1 nan
CHEMBL1434916 35141 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 2 0 4 4.8 Cc1nc(Oc2ccccc2C)c2oc3ccccc3c2n1 nan
16025666 35264 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 7 4.3 Cc1ccc(-n2nnc(-c3nsc(NC(=O)c4ccc(C)c(C)c4)n3)c2C)cc1 nan
CHEMBL1436433 35264 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 7 4.3 Cc1ccc(-n2nnc(-c3nsc(NC(=O)c4ccc(C)c(C)c4)n3)c2C)cc1 nan
16015798 35285 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 4 5.6 Cc1ccc(-c2nc3cc(Cl)ccc3o2)cc1NC(=O)COc1ccc(F)cc1 nan
CHEMBL1436774 35285 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 4 5.6 Cc1ccc(-c2nc3cc(Cl)ccc3o2)cc1NC(=O)COc1ccc(F)cc1 nan
16018841 35334 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 4 5.0 Cc1c(C(=O)Nc2ccc(F)cc2F)oc2ccc3c(c12)C(=O)CC(C)(C)O3 nan
CHEMBL1437356 35334 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 4 5.0 Cc1c(C(=O)Nc2ccc(F)cc2F)oc2ccc3c(c12)C(=O)CC(C)(C)O3 nan
1004026 35364 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 6 5.2 CCOc1ccccc1NC(=O)c1sc2nc(-c3ccc(OC)cc3)ccc2c1N nan
CHEMBL1437726 35364 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 6 5.2 CCOc1ccccc1NC(=O)c1sc2nc(-c3ccc(OC)cc3)ccc2c1N nan
16022287 35465 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 1 4 3.3 CCCCNC(=O)c1cccc(-n2c(C)nc3cccnc32)c1 nan
CHEMBL1438563 35465 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 1 4 3.3 CCCCNC(=O)c1cccc(-n2c(C)nc3cccnc32)c1 nan
5809896 35526 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 4.0 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2ccncc2)c1 nan
CHEMBL1439160 35526 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 4.0 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2ccncc2)c1 nan
15988173 35546 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 2 4 2.9 Cc1ccc(CNC(=O)c2ccc3c(=O)n(-c4ccccc4)c(=O)[nH]c3c2)cc1 nan
CHEMBL1439335 35546 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 2 4 2.9 Cc1ccc(CNC(=O)c2ccc3c(=O)n(-c4ccccc4)c(=O)[nH]c3c2)cc1 nan
1454908 36037 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 3 1 4 3.5 Sc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1443793 36037 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 3 1 4 3.5 Sc1nc(COc2ccccc2)nc2ccccc12 nan
1234247 36280 10 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 1 1 5 2.7 Cc1nnc(S)c2nn(-c3ccccc3)c(C)c12 nan
CHEMBL1446078 36280 10 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 1 1 5 2.7 Cc1nnc(S)c2nn(-c3ccccc3)c(C)c12 nan
16026772 36337 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 1.8 Cc1ccc(C(=O)NCC(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 nan
CHEMBL1446594 36337 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 1.8 Cc1ccc(C(=O)NCC(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 nan
2957415 36705 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 0 5 2.5 CC(=O)c1nc(N2C(=O)C3CC=C(C)CC3C2=O)sc1C nan
CHEMBL1449518 36705 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 0 5 2.5 CC(=O)c1nc(N2C(=O)C3CC=C(C)CC3C2=O)sc1C nan
2334194 36756 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 8 3.6 CCOC(=O)c1c(NS(=O)(=O)c2ccccc2)n(CCCOC)c2nc3ccccc3nc12 nan
CHEMBL1449923 36756 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 8 3.6 CCOC(=O)c1c(NS(=O)(=O)c2ccccc2)n(CCCOC)c2nc3ccccc3nc12 nan
4977513 36793 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(OC(C)C)cc2)no1 nan
CHEMBL1450219 36793 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(OC(C)C)cc2)no1 nan
2945668 36968 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 1.8 CCc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
CHEMBL1451692 36968 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 1.8 CCc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
24792337 37046 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 2 7 1.6 Cc1cc2nnc(SCC(=O)NC3CCCCC3)n2c(N)n1 nan
CHEMBL1452223 37046 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 2 7 1.6 Cc1cc2nnc(SCC(=O)NC3CCCCC3)n2c(N)n1 nan
15988498 37086 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 11 2 9 2.9 CCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)NCc3cccc(OC)c3OC)c2=O)CC1 nan
CHEMBL1452564 37086 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 11 2 9 2.9 CCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)NCc3cccc(OC)c3OC)c2=O)CC1 nan
2298970 37092 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3ccncc3)cc2)c1C nan
CHEMBL1452655 37092 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3ccncc3)cc2)c1C nan
24790128 37384 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 5 3.2 COc1ccc(-c2[nH]ncc2CN2CCN(C(=O)c3cccs3)CC2)c(F)c1 nan
CHEMBL1454939 37384 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 5 3.2 COc1ccc(-c2[nH]ncc2CN2CCN(C(=O)c3cccs3)CC2)c(F)c1 nan
16030361 37444 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 9 1 5 4.7 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCCc2ccccc2)c1 nan
CHEMBL1455531 37444 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 9 1 5 4.7 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCCc2ccccc2)c1 nan
16025668 37643 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 8 4.6 COc1ccc(-n2nnc(-c3nsc(NC(=O)c4ccc(C)c(C)c4)n3)c2C)cc1Cl nan
CHEMBL1457411 37643 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 8 4.6 COc1ccc(-n2nnc(-c3nsc(NC(=O)c4ccc(C)c(C)c4)n3)c2C)cc1Cl nan
1355891 37759 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 11 1 7 3.2 COc1ccc(OC)c(N(CC(=O)NCc2ccccc2)S(=O)(=O)c2ccc(OC)c(OC)c2)c1 nan
CHEMBL1458278 37759 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 11 1 7 3.2 COc1ccc(OC)c(N(CC(=O)NCc2ccccc2)S(=O)(=O)c2ccc(OC)c(OC)c2)c1 nan
2949787 37857 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.4 COc1ccccc1C1C(C(=O)c2ccco2)=C(O)C(=O)N1c1cc(C)on1 nan
CHEMBL1459163 37857 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.4 COc1ccccc1C1C(C(=O)c2ccco2)=C(O)C(=O)N1c1cc(C)on1 nan
1445336 37861 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 0 8 3.9 COc1ccccc1N1CCN(C(=O)CSc2ncnc3c2cnn3-c2ccc(C)c(C)c2)CC1 nan
CHEMBL1459184 37861 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 0 8 3.9 COc1ccccc1N1CCN(C(=O)CSc2ncnc3c2cnn3-c2ccc(C)c(C)c2)CC1 nan
6033330 38001 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 11 1 8 3.9 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
CHEMBL1460387 38001 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 11 1 8 3.9 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
5160710 38041 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 2 2 4.5 CCCOc1ccc(NC(=O)c2cc3cc(C)ccc3[nH]2)cc1 nan
CHEMBL1460665 38041 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 2 2 4.5 CCCOc1ccc(NC(=O)c2cc3cc(C)ccc3[nH]2)cc1 nan
3502512 38127 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 2 8 1.0 N#Cc1c(N2CCOCC2)nc(N)c2c(N)nc3c(c12)CC(CCl)O3 nan
CHEMBL1461443 38127 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 2 8 1.0 N#Cc1c(N2CCOCC2)nc(N)c2c(N)nc3c(c12)CC(CCl)O3 nan
2810150 38210 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 5 4.1 Cc1csc2c(=O)sc(NC(=O)c3ccc(F)cc3Cl)nc12 nan
CHEMBL1462227 38210 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 5 4.1 Cc1csc2c(=O)sc(NC(=O)c3ccc(F)cc3Cl)nc12 nan
4524521 38245 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 7 0.2 Cn1c(C(=O)NCCN2CCOCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1462442 38245 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 7 0.2 Cn1c(C(=O)NCCN2CCOCC2)cc2c(=O)n3ccccc3nc21 nan
1491130 38302 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 5 1 5 3.3 O=C(O)COc1ccc(-c2nccc(-c3cccs3)n2)cc1 nan
CHEMBL1462936 38302 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 5 1 5 3.3 O=C(O)COc1ccc(-c2nccc(-c3cccs3)n2)cc1 nan
135464100 38415 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 2 6 3.3 N#Cc1c(O)nc(SCC(=O)NC2CCCCC2)nc1-c1ccccc1 nan
CHEMBL1463888 38415 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 2 6 3.3 N#Cc1c(O)nc(SCC(=O)NC2CCCCC2)nc1-c1ccccc1 nan
2808819 38666 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 4.1 Cc1csc2ncnc(NC3CCN(Cc4ccccc4)CC3)c12 nan
CHEMBL1465720 38666 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 4.1 Cc1csc2ncnc(NC3CCN(Cc4ccccc4)CC3)c12 nan
1100812 38707 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 0 6 4.4 CCOC(=O)c1nn2c(C(F)(F)F)cc(-c3ccc(OC)cc3)nc2c1Br nan
CHEMBL1466098 38707 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 0 6 4.4 CCOC(=O)c1nn2c(C(F)(F)F)cc(-c3ccc(OC)cc3)nc2c1Br nan
665758 38727 8 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 7 4.3 COc1cc(OC)cc(-c2nc(-c3cc4cc(C)ccc4nc3OC)no2)c1 nan
CHEMBL1466279 38727 8 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 7 4.3 COc1cc(OC)cc(-c2nc(-c3cc4cc(C)ccc4nc3OC)no2)c1 nan
20953708 39029 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 7 3.2 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)nc(C)n3n2)cc1 nan
CHEMBL1468743 39029 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 7 3.2 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)nc(C)n3n2)cc1 nan
2913184 39126 15 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 7 3.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(F)cc2)s1 nan
CHEMBL1469528 39126 15 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 7 3.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(F)cc2)s1 nan
1226649 39150 14 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 2 4 4.1 CC(=O)NC(=S)Nc1ccc(-c2nc3ccc(C)cc3s2)cc1 nan
CHEMBL1469733 39150 14 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 2 4 4.1 CC(=O)NC(=S)Nc1ccc(-c2nc3ccc(C)cc3s2)cc1 nan
794237 39277 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 1 5 3.5 COc1ccc(C(=O)Nc2nnc(-c3ccccc3)s2)cc1 nan
CHEMBL1470825 39277 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 1 5 3.5 COc1ccc(C(=O)Nc2nnc(-c3ccccc3)s2)cc1 nan
1025062 39461 9 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 511 7 1 5 5.6 Cc1nc(SCC(=O)Nc2ccc(F)cc2)c(C#N)c(C)c1CC(=O)c1ccc(Br)cc1 nan
CHEMBL1472426 39461 9 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 511 7 1 5 5.6 Cc1nc(SCC(=O)Nc2ccc(F)cc2)c(C#N)c(C)c1CC(=O)c1ccc(Br)cc1 nan
16025800 39583 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 5 3.7 COCCCNC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1474073 39583 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 5 3.7 COCCCNC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
16017955 39600 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 5 3.3 Cc1ccc(NC(=O)c2nc(-c3ccncc3)no2)c(Cl)c1 nan
CHEMBL1474407 39600 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 5 3.3 Cc1ccc(NC(=O)c2nc(-c3ccncc3)no2)c(Cl)c1 nan
923699 39782 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 1 4 4.8 Cc1cc(C)cc(C(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)c1 nan
CHEMBL1476840 39782 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 1 4 4.8 Cc1cc(C)cc(C(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)c1 nan
16030273 39823 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccccc3F)CC2)cc1 nan
CHEMBL1477298 39823 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccccc3F)CC2)cc1 nan
3492613 40071 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 4 4.6 COc1ccc(-n2cc(-c3ccc(Br)cc3)nc2S)cc1 nan
CHEMBL1479477 40071 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 4 4.6 COc1ccc(-n2cc(-c3ccc(Br)cc3)nc2S)cc1 nan
1077503 40099 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 7 1.9 CCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1479731 40099 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 7 1.9 CCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
2059287 40380 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 0 5 3.5 CCCCN(CC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
CHEMBL1482087 40380 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 0 5 3.5 CCCCN(CC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
2490618 40399 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 9 0.0 CCc1ccc(OCC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1 nan
CHEMBL1482290 40399 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 9 0.0 CCc1ccc(OCC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1 nan
16020212 40850 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 562 7 2 8 3.8 Cc1ccc(NC(=O)Cn2c(=O)n(-c3ccccc3)c(=O)c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc32)cc1 nan
CHEMBL1486218 40850 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 562 7 2 8 3.8 Cc1ccc(NC(=O)Cn2c(=O)n(-c3ccccc3)c(=O)c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc32)cc1 nan
5835099 41315 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 1 6 5.0 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1C nan
CHEMBL1489865 41315 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 1 6 5.0 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1C nan
24791694 41412 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 4 4.0 COc1ccc2cc(C(=O)C3CCCN(C(=O)c4cccnc4)C3)ccc2c1 nan
CHEMBL1490547 41412 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 4 4.0 COc1ccc2cc(C(=O)C3CCCN(C(=O)c4cccnc4)C3)ccc2c1 nan
135438626 41678 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 3 9 0.8 Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nc(N)cc(O)n1 nan
CHEMBL1492401 41678 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 3 9 0.8 Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nc(N)cc(O)n1 nan
16018070 41715 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 4 3.5 O=C(CCCn1c(=O)c2cccn2c2ccc(F)cc21)NCCc1ccccc1 nan
CHEMBL1492679 41715 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 4 3.5 O=C(CCCn1c(=O)c2cccn2c2ccc(F)cc21)NCCc1ccccc1 nan
1327115 41806 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 1 5 4.8 COc1cccc(-c2cc3c(=O)n(-c4ccccc4)c(=S)[nH]c3s2)c1 nan
CHEMBL1493481 41806 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 1 5 4.8 COc1cccc(-c2cc3c(=O)n(-c4ccccc4)c(=S)[nH]c3s2)c1 nan
3034554 41914 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 7 1.5 Cn1c(=S)c2nc(SCCN3CCCC3)[nH]c2n(C)c1=O nan
CHEMBL1494615 41914 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 7 1.5 Cn1c(=S)c2nc(SCCN3CCCC3)[nH]c2n(C)c1=O nan
976285 42311 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 0 5 2.1 Cc1csc2nc(=O)c(-c3ccccc3)nn12 nan
CHEMBL1498297 42311 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 0 5 2.1 Cc1csc2nc(=O)c(-c3ccccc3)nn12 nan
3127165 42581 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 0.5 CC(C(O)c1ccccc1)N(C)CCn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1500612 42581 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 0.5 CC(C(O)c1ccccc1)N(C)CCn1cnc2c1c(=O)n(C)c(=O)n2C nan
135413586 42661 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 2 10 3.0 CCOC(=O)Cc1csc(NC(=O)CSc2nc(O)c(C#N)c(-c3ccccc3)n2)n1 nan
CHEMBL1501394 42661 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 2 10 3.0 CCOC(=O)Cc1csc(NC(=O)CSc2nc(O)c(C#N)c(-c3ccccc3)n2)n1 nan
5903312 42800 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 8 0.1 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2ccccn2c1=O nan
CHEMBL1502541 42800 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 8 0.1 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2ccccn2c1=O nan
790333 43234 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1cc(S)c2cccc(C)c2n1 nan
CHEMBL1506363 43234 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1cc(S)c2cccc(C)c2n1 nan
2146623 43566 17 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 4 5.0 CC(=O)c1ccc(NC(=O)c2ccc(CSc3ccccc3)o2)cc1 nan
CHEMBL1509267 43566 17 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 4 5.0 CC(=O)c1ccc(NC(=O)c2ccc(CSc3ccccc3)o2)cc1 nan
4617873 43882 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 2 3 4.4 NC(=O)c1ccc(NC(=O)c2ccc(COc3ccccc3Br)cc2)cc1 nan
CHEMBL1512241 43882 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 2 3 4.4 NC(=O)c1ccc(NC(=O)c2ccc(COc3ccccc3Br)cc2)cc1 nan
7877577 43982 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 7 1.4 O=C(CNC(=O)c1ccc(F)cc1)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1513627 43982 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 7 1.4 O=C(CNC(=O)c1ccc(F)cc1)OCc1cc(=O)n2ccsc2n1 nan
7598873 44020 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 3 3.9 CCc1ccccc1NC(=O)c1cccn(Cc2ccccc2F)c1=O nan
CHEMBL1514321 44020 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 3 3.9 CCc1ccccc1NC(=O)c1cccn(Cc2ccccc2F)c1=O nan
16030561 44033 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 6 0 5 5.5 O=C(CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1)N1CCN(c2ccccc2F)CC1 nan
CHEMBL1514538 44033 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 6 0 5 5.5 O=C(CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1)N1CCN(c2ccccc2F)CC1 nan
16009347 44036 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 0 5 4.6 Cc1cc(C)cc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1 nan
CHEMBL1514567 44036 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 0 5 4.6 Cc1cc(C)cc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1 nan
16018206 44046 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1cc(NC(=O)c2oc3c(c2C)-c2nn(Cc4cccc(Cl)c4)cc2CC3)cc(OC)c1 nan
CHEMBL1514692 44046 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1cc(NC(=O)c2oc3c(c2C)-c2nn(Cc4cccc(Cl)c4)cc2CC3)cc(OC)c1 nan
3207800 44295 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)c2nc(SCC(=O)Nc3cc(C)on3)c(C#N)cc2c1 nan
CHEMBL1517790 44295 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)c2nc(SCC(=O)Nc3cc(C)on3)c(C#N)cc2c1 nan
2091511 44347 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 0 8 2.5 Cc1ccc2nc(CSc3nnc(-c4ccncc4)n3C)cc(=O)n2c1 nan
CHEMBL1518274 44347 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 0 8 2.5 Cc1ccc2nc(CSc3nnc(-c4ccncc4)n3C)cc(=O)n2c1 nan
24818303 44349 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 1 3 4.4 CN(C)C(=O)c1ccc(NC(=O)c2sccc2-c2ccccc2)cc1 nan
CHEMBL1518303 44349 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 1 3 4.4 CN(C)C(=O)c1ccc(NC(=O)c2sccc2-c2ccccc2)cc1 nan
5151092 44352 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 1 2 3.2 CNC(=O)c1c2c(nc3ccc(Br)cc13)CCCC2 nan
CHEMBL1518360 44352 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 1 2 3.2 CNC(=O)c1c2c(nc3ccc(Br)cc13)CCCC2 nan
16019804 44516 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 9 1 8 1.6 CCCn1c(=O)c2sccc2n2c(CCCC(=O)NCCOC)nnc12 nan
CHEMBL1519737 44516 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 9 1 8 1.6 CCCn1c(=O)c2sccc2n2c(CCCC(=O)NCCOC)nnc12 nan
4917226 44582 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 2 4 5.8 O=C(O)CC(NC(=O)c1sc2ccccc2c1Cl)c1ccc(OC2CCCC2)cc1 nan
CHEMBL1520355 44582 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 2 4 5.8 O=C(O)CC(NC(=O)c1sc2ccccc2c1Cl)c1ccc(OC2CCCC2)cc1 nan
24677542 44659 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 8 4 5 3.0 CCCCCNC(=O)c1ccc(NS(=O)(=O)c2ccc3[nH]c(O)nc3c2)cc1 nan
CHEMBL1520946 44659 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 8 4 5 3.0 CCCCCNC(=O)c1ccc(NS(=O)(=O)c2ccc3[nH]c(O)nc3c2)cc1 nan
902803 44825 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 5 1 2 4.5 O=C(Nc1ccccc1)c1ccc(COc2ccccc2)cc1 nan
CHEMBL1522424 44825 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 5 1 2 4.5 O=C(Nc1ccccc1)c1ccc(COc2ccccc2)cc1 nan
15988611 45032 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 8 3.9 CC(=O)c1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1524392 45032 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 8 3.9 CC(=O)c1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1 nan
3239863 45192 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 0 8 2.4 CCOC(=O)CC(=O)CSc1ccc2nnc(-c3ccccc3)n2n1 nan
CHEMBL1525909 45192 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 0 8 2.4 CCOC(=O)CC(=O)CSc1ccc2nnc(-c3ccccc3)n2n1 nan
2930800 45272 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 2 7 2.5 COC(=O)c1sc(NC(=O)C2CCCCC2C(=O)O)c(C(=O)OC)c1C nan
CHEMBL1526492 45272 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 2 7 2.5 COC(=O)c1sc(NC(=O)C2CCCCC2C(=O)O)c(C(=O)OC)c1C nan
2349018 45454 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 2 1 4 3.4 CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1528175 45454 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 2 1 4 3.4 CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
1355435 45468 11 None -22 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 0 4 3.3 Cc1cn(S(=O)(=O)c2ccc(Br)c3ccccc23)cn1 nan
CHEMBL1528299 45468 11 None -22 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 0 4 3.3 Cc1cn(S(=O)(=O)c2ccc(Br)c3ccccc23)cn1 nan
5073065 45566 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 1 6 -0.6 O=C(Cn1cnc2ccccc2c1=O)NCC(=O)N1CCOCC1 nan
CHEMBL1529152 45566 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 1 6 -0.6 O=C(Cn1cnc2ccccc2c1=O)NCC(=O)N1CCOCC1 nan
3240741 45659 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 9 1 8 4.6 COc1ccc(CC(=O)Nc2ccc(-c3noc(-c4cc(OC)c(OC)c(OC)c4)n3)cc2)cc1 nan
CHEMBL1529936 45659 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 9 1 8 4.6 COc1ccc(CC(=O)Nc2ccc(-c3noc(-c4cc(OC)c(OC)c(OC)c4)n3)cc2)cc1 nan
3212225 45684 2 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 3.1 Cc1cc(C)c2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
CHEMBL1530244 45684 2 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 3.1 Cc1cc(C)c2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
16024952 45686 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.0 CCOC(=O)c1cccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)c1 nan
CHEMBL1530263 45686 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.0 CCOC(=O)c1cccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)c1 nan
16017576 45697 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 7 2.2 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
CHEMBL1530393 45697 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 7 2.2 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
4907979 45706 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 2 6 3.0 OCCCNc1ncnc2sc3c(c12)CCN(Cc1ccccc1)C3 nan
CHEMBL1530465 45706 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 2 6 3.0 OCCCNc1ncnc2sc3c(c12)CCN(Cc1ccccc1)C3 nan
1161207 45787 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 8 2 7 3.1 COc1ccccc1OCC(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
CHEMBL1531098 45787 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 8 2 7 3.1 COc1ccccc1OCC(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
1355556 45851 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 3 1 3 3.8 O=S(=O)(Nc1cccnc1)c1ccc(Br)c2ccccc12 nan
CHEMBL1531651 45851 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 3 1 3 3.8 O=S(=O)(Nc1cccnc1)c1ccc(Br)c2ccccc12 nan
16025786 46072 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 1 4 5.3 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccc(F)cc3)CC2)s1 nan
CHEMBL1533608 46072 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 1 4 5.3 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccc(F)cc3)CC2)s1 nan
3151323 46158 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.3 Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1534442 46158 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.3 Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CC4CCCO4)c3nc12 nan
3238163 46399 7 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 8 0.6 Cc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
CHEMBL1536880 46399 7 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 8 0.6 Cc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
2989967 46482 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 3.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)no1 nan
CHEMBL1537625 46482 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 3.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)no1 nan
767265 46737 34 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 1 5 3.5 Sc1nnc(-c2ccco2)n1-c1ccc(Cl)cc1 nan
CHEMBL1539766 46737 34 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 1 5 3.5 Sc1nnc(-c2ccco2)n1-c1ccc(Cl)cc1 nan
891408 47173 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 259 4 0 6 1.7 O=C(OCc1cccc([N+](=O)[O-])c1)c1cnccn1 nan
CHEMBL1543385 47173 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 259 4 0 6 1.7 O=C(OCc1cccc([N+](=O)[O-])c1)c1cnccn1 nan
4634206 47265 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 2 10 -0.9 CCOc1ccccc1OCC(=O)NNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1544116 47265 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 2 10 -0.9 CCOc1ccccc1OCC(=O)NNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
1487485 47269 21 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 1 0 3 3.1 Cc1ccc(-n2ncc(Br)c(Br)c2=O)cc1 nan
CHEMBL1544131 47269 21 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 1 0 3 3.1 Cc1ccc(-n2ncc(Br)c(Br)c2=O)cc1 nan
1867273 47355 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
CHEMBL1544770 47355 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
3781367 47407 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 2 8 4.2 CCOc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
CHEMBL1545158 47407 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 2 8 4.2 CCOc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
28358049 47654 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 4 3.3 CCN(CC)Cc1c(O)c(Cl)cc2c(C)cc(=O)oc12 nan
5398465 47654 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 4 3.3 CCN(CC)Cc1c(O)c(Cl)cc2c(C)cc(=O)oc12 nan
CHEMBL1547311 47654 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 4 3.3 CCN(CC)Cc1c(O)c(Cl)cc2c(C)cc(=O)oc12 nan
7080334 47665 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 5 3.6 Cc1c(-c2cccc(NC(=O)c3ccco3)c2)nc2ncccn12 nan
CHEMBL1547414 47665 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 5 3.6 Cc1c(-c2cccc(NC(=O)c3ccco3)c2)nc2ncccn12 nan
1476696 47692 24 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 0 4 4.8 CSc1cc(-c2ccc(Cl)cc2)n(Cc2ccccc2)c(=O)c1C#N nan
CHEMBL1547693 47692 24 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 0 4 4.8 CSc1cc(-c2ccc(Cl)cc2)n(Cc2ccccc2)c(=O)c1C#N nan
3830390 47786 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 2 8 -1.2 CN(N)N=Nc1nc2c(=O)n(C)c(=O)n(C)c2[nH]1 nan
CHEMBL1548599 47786 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 2 8 -1.2 CN(N)N=Nc1nc2c(=O)n(C)c(=O)n(C)c2[nH]1 nan
20885691 48087 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 7 1 6 1.9 CCc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
CHEMBL1551091 48087 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 7 1 6 1.9 CCc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
2053967 48106 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 0 5 4.3 CCCCN(CCCC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
CHEMBL1551348 48106 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 0 5 4.3 CCCCN(CCCC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
7151074 48163 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.1 O=C(CSc1nccn1Cc1ccc(Cl)cc1)Nc1ccc2c(c1)OCCO2 nan
CHEMBL1552167 48163 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.1 O=C(CSc1nccn1Cc1ccc(Cl)cc1)Nc1ccc2c(c1)OCCO2 nan
16025798 48355 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 4 5.0 O=C(NCc1ccc(F)cc1)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1554965 48355 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 4 5.0 O=C(NCc1ccc(F)cc1)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
16019077 48413 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 5 4.3 O=C(NCCc1ccccc1Cl)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1555692 48413 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 5 4.3 O=C(NCCc1ccccc1Cl)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
2913061 48519 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 6 3.8 COc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1556761 48519 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 6 3.8 COc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
4158621 48565 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 4 2.9 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccc(F)cc1Cl nan
CHEMBL1557087 48565 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 4 2.9 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccc(F)cc1Cl nan
2448835 48952 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 2 9 1.4 CCCn1c(N)c(C(=O)CSc2nc3cc(Cl)c[nH]c-3n2)c(=O)n(C)c1=O nan
CHEMBL1560544 48952 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 2 9 1.4 CCCn1c(N)c(C(=O)CSc2nc3cc(Cl)c[nH]c-3n2)c(=O)n(C)c1=O nan
20921616 48999 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 1 8 2.6 COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)c3ccccc3)s2)cc1OC nan
CHEMBL1561011 48999 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 1 8 2.6 COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)c3ccccc3)s2)cc1OC nan
7190686 49174 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccccc1NC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1562578 49174 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccccc1NC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
3152540 49184 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.0 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1)c1ccco1 nan
CHEMBL1562668 49184 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.0 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1)c1ccco1 nan
4367682 49594 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 1 3 2.6 Cc1nc2ccc(Br)cc2c2c1CC(CO)O2 nan
CHEMBL1566103 49594 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 1 3 2.6 Cc1nc2ccc(Br)cc2c2c1CC(CO)O2 nan
1569279 49668 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 6 3.3 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCCN1CCOCC1 nan
CHEMBL1566690 49668 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 6 3.3 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCCN1CCOCC1 nan
7881996 49676 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 6 1 8 1.2 COc1cccc(C(=O)NCC(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
CHEMBL1566736 49676 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 6 1 8 1.2 COc1cccc(C(=O)NCC(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
3146574 49742 15 None -4 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 8 3.2 COc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1567207 49742 15 None -4 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 8 3.2 COc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
1226038 49913 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 3 0 3 5.3 CC(C)c1ccc(-c2cc(C(=O)N3CCOCC3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1568600 49913 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 3 0 3 5.3 CC(C)c1ccc(-c2cc(C(=O)N3CCOCC3)c3cc(Br)ccc3n2)cc1 nan
20904702 50004 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 8 1 8 2.1 CCCn1c(=O)c2sccc2n2c(CCCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1569451 50004 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 8 1 8 2.1 CCCn1c(=O)c2sccc2n2c(CCCC(=O)NCC3CCCO3)nnc12 nan
16017333 50056 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 7 1.6 COc1cccc(C(=O)Nc2nnc(S(=O)(=O)N3CCCC3)s2)c1 nan
CHEMBL1569922 50056 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 7 1.6 COc1cccc(C(=O)Nc2nnc(S(=O)(=O)N3CCCC3)s2)c1 nan
1840878 50067 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 2 7 1.8 N#C/C(=C\c1c(N2CCC(C(N)=O)CC2)nc2ccccn2c1=O)C(=O)NC1CCCCC1 nan
CHEMBL1570011 50067 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 2 7 1.8 N#C/C(=C\c1c(N2CCC(C(N)=O)CC2)nc2ccccn2c1=O)C(=O)NC1CCCCC1 nan
2134950 50184 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 6 4.0 Cc1cccc(Cn2c(=O)n(CCC(=O)NCCc3ccc(Cl)cc3)c(=O)c3sccc32)c1 nan
CHEMBL1570886 50184 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 6 4.0 Cc1cccc(Cn2c(=O)n(CCC(=O)NCCc3ccc(Cl)cc3)c(=O)c3sccc32)c1 nan
16017067 50513 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 1 5 4.8 CCC(C(=O)NCc1ccccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1574126 50513 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 1 5 4.8 CCC(C(=O)NCc1ccccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O nan
860331 50621 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 4 1 3 3.7 Cc1cc2ccccc2nc1SCC(=O)NC1CCCC1 nan
CHEMBL1575355 50621 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 4 1 3 3.7 Cc1cc2ccccc2nc1SCC(=O)NC1CCCC1 nan
3771682 50711 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 5 5.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(C(C)C)cc2)n1 nan
CHEMBL1576217 50711 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 5 5.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(C(C)C)cc2)n1 nan
20957197 50778 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 9 2.0 COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1576697 50778 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 9 2.0 COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
5738492 50967 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 7 1 6 3.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc3c(c2)CC(C)O3)C1c1cccnc1 nan
CHEMBL1578334 50967 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 7 1 6 3.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc3c(c2)CC(C)O3)C1c1cccnc1 nan
2503775 51020 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 6 1 5 2.3 O=C(CSc1nnc2ccccn12)NCCc1ccc(F)cc1 nan
CHEMBL1578723 51020 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 6 1 5 2.3 O=C(CSc1nnc2ccccn12)NCCc1ccc(F)cc1 nan
4605879 51042 10 None -3 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 7 2.3 C=CCSc1nc(O)c2c(n1)OC(N)=C(C#N)C2C(C)C nan
CHEMBL1578918 51042 10 None -3 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 7 2.3 C=CCSc1nc(O)c2c(n1)OC(N)=C(C#N)C2C(C)C nan
2366506 51212 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 2.9 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc2c(c1)OCCO2 nan
CHEMBL1580473 51212 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 2.9 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc2c(c1)OCCO2 nan
135433335 51426 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.7 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccn1 nan
1426566 51426 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.7 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccn1 nan
CHEMBL1582229 51426 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.7 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccn1 nan
5310097 51447 1 None -4 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 6 2.7 Cc1ccc(-c2nnc3ccc(SC(C)C(=O)O)nn23)cc1 nan
CHEMBL1582406 51447 1 None -4 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 6 2.7 Cc1ccc(-c2nnc3ccc(SC(C)C(=O)O)nn23)cc1 nan
4099137 51514 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 9 2 6 4.4 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1ccccc1Cl nan
CHEMBL1583052 51514 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 9 2 6 4.4 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1ccccc1Cl nan
661828 52092 14 None -14 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1ccc(OC)c(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1587683 52092 14 None -14 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1ccc(OC)c(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
2004544 52227 16 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 5 4.2 O=C(CSc1ncnc2c1oc1ccccc12)Nc1ccccc1F nan
CHEMBL1588950 52227 16 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 5 4.2 O=C(CSc1ncnc2c1oc1ccccc12)Nc1ccccc1F nan
1003437 52433 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 3 2 5 5.3 Cc1cc(F)ccc1NC(=O)c1sc2nc(-c3cccs3)ccc2c1N nan
CHEMBL1591017 52433 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 3 2 5 5.3 Cc1cc(F)ccc1NC(=O)c1sc2nc(-c3cccs3)ccc2c1N nan
16019053 52442 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 1 6 4.0 CCCSCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1591213 52442 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 1 6 4.0 CCCSCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16015858 52446 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 4 5.3 O=C(COc1ccccc1Cl)Nc1ccc2oc(-c3ccccc3F)nc2c1 nan
CHEMBL1591250 52446 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 4 5.3 O=C(COc1ccccc1Cl)Nc1ccc2oc(-c3ccccc3F)nc2c1 nan
16027414 52505 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 8 3.6 O=C(Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1)c1ccccc1 nan
CHEMBL1591957 52505 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 8 3.6 O=C(Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1)c1ccccc1 nan
16029938 52551 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 6 2.8 Cc1ccn2c(=O)c(NC(=O)c3cccc([N+](=O)[O-])c3C)c(C)nc2c1 nan
CHEMBL1592574 52551 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 6 2.8 Cc1ccn2c(=O)c(NC(=O)c3cccc([N+](=O)[O-])c3C)c(C)nc2c1 nan
15990931 52571 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 2 3 6.1 CC(C)c1ccc(Nc2cc(C(=O)NCCc3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1592841 52571 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 2 3 6.1 CC(C)c1ccc(Nc2cc(C(=O)NCCc3ccccc3)c3ccccc3n2)cc1 nan
801483 52688 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 2 4 5.2 Oc1cccc(-c2nc(-c3cccs3)c(-c3cccs3)[nH]2)c1 nan
CHEMBL1594404 52688 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 2 4 5.2 Oc1cccc(-c2nc(-c3cccs3)c(-c3cccs3)[nH]2)c1 nan
7189836 52882 11 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 7 3.3 COc1ccc(C(=O)Nc2nc3cc4c(cc3s2)OCO4)c(OC)c1 nan
CHEMBL1596046 52882 11 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 7 3.3 COc1ccc(C(=O)Nc2nc3cc4c(cc3s2)OCO4)c(OC)c1 nan
4137685 52928 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 5.8 COc1cccc(C(=O)c2sc3nc(-c4ccccc4)cc(C(F)(F)F)c3c2N)c1 nan
CHEMBL1596431 52928 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 5.8 COc1cccc(C(=O)c2sc3nc(-c4ccccc4)cc(C(F)(F)F)c3c2N)c1 nan
3916490 53051 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 8 1 7 2.7 CCN(CC)S(=O)(=O)c1cccc(NC(=O)COc2ncnc3sccc23)c1 nan
CHEMBL1597614 53051 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 8 1 7 2.7 CCN(CC)S(=O)(=O)c1cccc(NC(=O)COc2ncnc3sccc23)c1 nan
16195124 53246 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 7 1 6 2.4 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC)cc2)C12C(=O)N(C)c1ccccc12 nan
CHEMBL1599313 53246 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 7 1 6 2.4 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC)cc2)C12C(=O)N(C)c1ccccc12 nan
135419123 53387 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 2 1 3 5.5 Cc1ccc(C2=Nc3ccccc3N=C(c3ccc(F)cc3)C2)c(O)c1 nan
CHEMBL1600651 53387 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 2 1 3 5.5 Cc1ccc(C2=Nc3ccccc3N=C(c3ccc(F)cc3)C2)c(O)c1 nan
16018987 53398 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 8 1 7 3.7 COc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1OC nan
CHEMBL1600729 53398 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 8 1 7 3.7 COc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1OC nan
16009272 53647 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 3.2 COc1ccc(CNC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)cc1 nan
CHEMBL1603189 53647 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 3.2 COc1ccc(CNC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)cc1 nan
2816428 53765 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 2 0 5 2.8 C=CCn1c2ccccc2c2nn(C)c(=S)nc21 nan
CHEMBL1604034 53765 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 2 0 5 2.8 C=CCn1c2ccccc2c2nn(C)c(=S)nc21 nan
3765596 53938 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1605561 53938 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
4524651 54429 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 5 2.5 CC1CCCCC1NC(=O)c1cc2c(=O)n3ccccc3nc2n1C nan
CHEMBL1609461 54429 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 5 2.5 CC1CCCCC1NC(=O)c1cc2c(=O)n3ccccc3nc2n1C nan
901441 54440 10 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 1 1 3 3.3 Cc1cc2sc(C(=O)O)c(C)c2s1 nan
CHEMBL1609556 54440 10 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 1 1 3 3.3 Cc1cc2sc(C(=O)O)c(C)c2s1 nan
6498451 54521 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 9 1.8 COc1cc2c3nc4n(c(=O)c3n(CC(=O)NCC3CCCO3)c2cc1OC)CCS4 nan
CHEMBL1610295 54521 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 9 1.8 COc1cc2c3nc4n(c(=O)c3n(CC(=O)NCC3CCCO3)c2cc1OC)CCS4 nan
16022543 54579 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 2 8 4.1 CCN(CC)CCNC(=O)c1ccc2c(=O)n3nc(Nc4cccc(Cl)c4C)sc3nc2c1 nan
CHEMBL1610849 54579 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 2 8 4.1 CCN(CC)CCNC(=O)c1ccc2c(=O)n3nc(Nc4cccc(Cl)c4C)sc3nc2c1 nan
16013346 54702 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 1 5 4.2 Cc1cc2oc(C(=O)Nc3ccc(S(=O)(=O)N4CCCCCC4)cc3)cc(=O)c2cc1C nan
CHEMBL1611855 54702 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 1 5 4.2 Cc1cc2oc(C(=O)Nc3ccc(S(=O)(=O)N4CCCCCC4)cc3)cc(=O)c2cc1C nan
2816611 54766 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 2 7 2.8 CCOC(=O)N1CCc2c(sc3nc(S)nc(S)c23)C1 nan
CHEMBL1612443 54766 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 2 7 2.8 CCOC(=O)N1CCc2c(sc3nc(S)nc(S)c23)C1 nan
2967714 54800 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 4.5 COc1ccc(C(=O)Nc2ccc(C(=O)Nc3cccc(C)c3)cc2)cc1 nan
CHEMBL1612735 54800 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 4.5 COc1ccc(C(=O)Nc2ccc(C(=O)Nc3cccc(C)c3)cc2)cc1 nan
16019073 54838 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 8 1 6 4.1 CCOc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1613149 54838 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 8 1 6 4.1 CCOc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
4723782 55241 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 3 4.4 Brc1ccc(-c2ccc(CNCc3ccccn3)o2)cc1 nan
CHEMBL1342613 55241 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 3 4.4 Brc1ccc(-c2ccc(CNCc3ccccn3)o2)cc1 nan
CHEMBL1618192 55241 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 3 4.4 Brc1ccc(-c2ccc(CNCc3ccccn3)o2)cc1 nan
20279 55327 98 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
CHEMBL1619 55327 98 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
1712157 55553 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 6 1.6 O=C(NCCOC(=O)c1ccc([N+](=O)[O-])cc1)c1cccnc1 nan
CHEMBL1455081 55553 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 6 1.6 O=C(NCCOC(=O)c1ccc([N+](=O)[O-])cc1)c1cccnc1 nan
CHEMBL1620984 55553 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 6 1.6 O=C(NCCOC(=O)c1ccc([N+](=O)[O-])cc1)c1cccnc1 nan
616262 55691 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 5 2.8 CC(=O)c1sc(Nc2ccccn2)nc1C nan
CHEMBL1505364 55691 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 5 2.8 CC(=O)c1sc(Nc2ccccn2)nc1C nan
CHEMBL1622190 55691 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 5 2.8 CC(=O)c1sc(Nc2ccccn2)nc1C nan
1554378 56126 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 6 1 5 3.7 CN(C)CCCNc1ncnc2scc(-c3ccccc3)c12 nan
CHEMBL1577432 56126 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 6 1 5 3.7 CN(C)CCCNc1ncnc2scc(-c3ccccc3)c12 nan
CHEMBL1625977 56126 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 6 1 5 3.7 CN(C)CCCNc1ncnc2scc(-c3ccccc3)c12 nan
3098134 72059 5 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.6 C=CCN1C(=O)/C(=C2/Sc3ccc(OC)cc3N2C)S/C1=N\c1cccc(O)c1 nan
CHEMBL1977502 72059 5 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.6 C=CCN1C(=O)/C(=C2/Sc3ccc(OC)cc3N2C)S/C1=N\c1cccc(O)c1 nan
9687993 107776 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 6 2.7 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1cccc([N+](=O)[O-])c1 nan
CHEMBL3191955 107776 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 6 2.7 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1cccc([N+](=O)[O-])c1 nan
3095208 107965 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 2 4 2.6 O=C1C=C(Nc2ccccc2C(=O)O)c2ccccc2C1=O nan
CHEMBL3194086 107965 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 2 4 2.6 O=C1C=C(Nc2ccccc2C(=O)O)c2ccccc2C1=O nan
9638310 108145 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 4 1 6 1.5 C/C(=N\NC(=O)c1cnccn1)c1ccc([N+](=O)[O-])cc1 nan
CHEMBL3196238 108145 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 4 1 6 1.5 C/C(=N\NC(=O)c1cnccn1)c1ccc([N+](=O)[O-])cc1 nan
102175 141247 72 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 4 9 -1.5 CNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O nan
CHEMBL383144 141247 72 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 4 9 -1.5 CNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O nan
6083 204792 95 None -44 7 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O nan
CHEMBL1315633 204792 95 None -44 7 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O nan
CHEMBL752 204792 95 None -44 7 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O nan
4324298 28596 6 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 0.9 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccc(=O)n(C)n2)c1 nan
CHEMBL1377104 28596 6 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 0.9 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccc(=O)n(C)n2)c1 nan
15988970 44027 7 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 3 6.2 CCc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)cc1 nan
CHEMBL1514445 44027 7 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 3 6.2 CCc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)cc1 nan
15988960 48494 7 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 3 5.5 CC(C)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1556439 48494 7 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 3 5.5 CC(C)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
3119935 52675 19 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 2 6 3.7 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
CHEMBL1594298 52675 19 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 2 6 3.7 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
735254 10426 80 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 178 1 1 3 2.4 S=c1[nH]nc(-c2ccccc2)o1 nan
CHEMBL1164316 10426 80 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 178 1 1 3 2.4 S=c1[nH]nc(-c2ccccc2)o1 nan
5904441 11319 14 None -6 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 1 5 3.1 N#C/C(=C\c1ccc([N+](=O)[O-])o1)c1nc2ccccc2[nH]1 nan
CHEMBL117966 11319 14 None -6 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 1 5 3.1 N#C/C(=C\c1ccc([N+](=O)[O-])o1)c1nc2ccccc2[nH]1 nan
1004068 18330 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)cc1 nan
CHEMBL1271076 18330 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)cc1 nan
3626929 19510 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 1 5 3.7 CC(=O)c1ccc(NC(=O)C(=O)c2cn(CC(=O)N3CCCCC3)c3ccccc23)cc1 nan
CHEMBL1299573 19510 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 1 5 3.7 CC(=O)c1ccc(NC(=O)C(=O)c2cn(CC(=O)N3CCCCC3)c3ccccc23)cc1 nan
5852174 19600 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 7 4.0 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1300425 19600 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 7 4.0 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
15988009 19679 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1300978 19679 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
3688325 19770 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 6 2.9 CC(=O)Nc1cccc(C2=CC(c3ccco3)n3ncnc3N2)c1 nan
CHEMBL1301688 19770 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 6 2.9 CC(=O)Nc1cccc(C2=CC(c3ccco3)n3ncnc3N2)c1 nan
20957233 19810 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 8 2.3 CC(CNC(=O)CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)c1ccccc1 nan
CHEMBL1302111 19810 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 8 2.3 CC(CNC(=O)CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)c1ccccc1 nan
17584169 19923 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 5 3.3 O=C(COc1cc2oc(=O)c3c(c2cc1Cl)CCC3)Nc1ccccn1 nan
CHEMBL1302915 19923 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 5 3.3 O=C(COc1cc2oc(=O)c3c(c2cc1Cl)CCC3)Nc1ccccn1 nan
852288 20086 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 1 5 0.9 Cn1c(C(=O)O)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1304220 20086 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 1 5 0.9 Cn1c(C(=O)O)cc2c(=O)n3ccccc3nc21 nan
4145244 20095 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 0.6 Cn1cnnc1SCC(=O)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1304271 20095 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 0.6 Cn1cnnc1SCC(=O)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
2429052 20195 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 5 5.8 O=C(COC(=O)CSc1cccc2cccc(Cl)c12)Nc1ncc(C(F)(F)F)cc1Cl nan
CHEMBL1305188 20195 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 5 5.8 O=C(COC(=O)CSc1cccc2cccc(Cl)c12)Nc1ncc(C(F)(F)F)cc1Cl nan
353380 20365 2 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 2 2 2 5.7 O=C(Nc1ccc(Br)c2ccccc12)c1ccc2ccccc2c1O nan
CHEMBL1306524 20365 2 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 2 2 2 5.7 O=C(Nc1ccc(Br)c2ccccc12)c1ccc2ccccc2c1O nan
4300736 20493 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 3 2 7 2.0 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4c(c3)OCCO4)sc2c1 nan
CHEMBL1307550 20493 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 3 2 7 2.0 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4c(c3)OCCO4)sc2c1 nan
16194293 20525 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 6 1 8 3.4 CCc1nnc(NC(=O)CSc2ccc(-c3cccs3)nn2)s1 nan
CHEMBL1307806 20525 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 6 1 8 3.4 CCc1nnc(NC(=O)CSc2ccc(-c3cccs3)nn2)s1 nan
24819826 20550 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 6 2 3 4.1 O=C(NCCCSc1ccccc1)c1cc(Br)ccc1O nan
CHEMBL1307980 20550 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 6 2 3 4.1 O=C(NCCCSc1ccccc1)c1cc(Br)ccc1O nan
713805 20606 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 4 0 9 0.6 COc1nc(N2CCCC2)nc(-n2nnc(C(C)=O)c2C)n1 nan
CHEMBL1308437 20606 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 4 0 9 0.6 COc1nc(N2CCCC2)nc(-n2nnc(C(C)=O)c2C)n1 nan
935829 20624 17 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 0 4 3.3 Cc1nc2ccccc2nc1SCC(=O)N1CCC(C)CC1 nan
CHEMBL1308605 20624 17 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 0 4 3.3 Cc1nc2ccccc2nc1SCC(=O)N1CCC(C)CC1 nan
2815890 20669 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 5 10 -1.9 CNc1nc2c(N)ncnc2n1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O nan
CHEMBL1308946 20669 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 5 10 -1.9 CNc1nc2c(N)ncnc2n1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O nan
4619601 20676 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 0 7 2.2 CCN(C(=O)CSC1=Nc2ccccc2C2CC=NN12)C1CCS(=O)(=O)C1 nan
CHEMBL1309010 20676 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 0 7 2.2 CCN(C(=O)CSC1=Nc2ccccc2C2CC=NN12)C1CCS(=O)(=O)C1 nan
4038913 20769 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 0 6 3.9 CCN(C(=O)COC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12)C1CCS(=O)(=O)C1 nan
CHEMBL1309767 20769 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 0 6 3.9 CCN(C(=O)COC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12)C1CCS(=O)(=O)C1 nan
20923170 20866 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1C nan
CHEMBL1310648 20866 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1C nan
3163618 20903 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 3.6 Cc1ccc(NC(=O)CSc2nnc(-c3ccncc3)s2)cc1 nan
CHEMBL1310953 20903 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 3.6 Cc1ccc(NC(=O)CSc2nnc(-c3ccncc3)s2)cc1 nan
1504615 20952 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 6 2.0 Cc1cc(CNC(=O)Cn2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
CHEMBL1311384 20952 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 6 2.0 Cc1cc(CNC(=O)Cn2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
652682 21011 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 8 1 6 4.3 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccncc2)c1 nan
CHEMBL1311808 21011 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 8 1 6 4.3 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccncc2)c1 nan
24892134 21028 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 2.7 Cn1c(=O)c2c(SCC(=O)Nc3ccccc3F)nc(-c3ccccc3F)nc2n(C)c1=O nan
CHEMBL1311956 21028 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 2.7 Cn1c(=O)c2c(SCC(=O)Nc3ccccc3F)nc(-c3ccccc3F)nc2n(C)c1=O nan
2769005 21201 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 4 0 7 1.1 CCOC(=O)CSc1nc(=O)n2cc(C)ccc2n1 nan
CHEMBL1313156 21201 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 4 0 7 1.1 CCOC(=O)CSc1nc(=O)n2cc(C)ccc2n1 nan
20914264 21204 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.9 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)cc1 nan
CHEMBL1313185 21204 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.9 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)cc1 nan
4002385 21227 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
662194 21227 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1313374 21227 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
16033288 21352 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 5 5.3 Cc1ccc(C)c(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
CHEMBL1314411 21352 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 5 5.3 Cc1ccc(C)c(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
1046209 21420 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 2 1 8 2.8 Cn1c(=O)c2c(nc3n(-c4ccc(O)cc4)c(-c4ccc(Br)cc4)cn23)n(C)c1=O nan
CHEMBL1315398 21420 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 2 1 8 2.8 Cn1c(=O)c2c(nc3n(-c4ccc(O)cc4)c(-c4ccc(Br)cc4)cn23)n(C)c1=O nan
16014663 21431 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 6 3.8 COc1ccc(-c2nsc(NC(=O)COc3ccc(C)c(C)c3)n2)cc1 nan
CHEMBL1315498 21431 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 6 3.8 COc1ccc(-c2nsc(NC(=O)COc3ccc(C)c(C)c3)n2)cc1 nan
16017636 21479 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 5 2 8 4.3 COc1ccc(NC(=O)c2sc3nc(-c4cc5ccc(OC)cc5oc4=O)[nH]c(=O)c3c2C)cc1 nan
CHEMBL1316057 21479 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 5 2 8 4.3 COc1ccc(NC(=O)c2sc3nc(-c4cc5ccc(OC)cc5oc4=O)[nH]c(=O)c3c2C)cc1 nan
16018724 21485 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 7 4.2 COc1ccc(Cl)cc1NC(=O)CSc1nnc(C)n2c1cc1occc12 nan
CHEMBL1316127 21485 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 7 4.2 COc1ccc(Cl)cc1NC(=O)CSc1nnc(C)n2c1cc1occc12 nan
16009825 21538 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1cc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc(OC)c1 nan
CHEMBL1316937 21538 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1cc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc(OC)c1 nan
24980344 21541 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 5 3.0 Cc1ccc(C(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
CHEMBL1316966 21541 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 5 3.0 Cc1ccc(C(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
7159295 21560 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 6 1 9 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2ccccc2)c1=O nan
CHEMBL1317213 21560 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 6 1 9 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2ccccc2)c1=O nan
17757011 21565 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 2 1 4 5.3 O=C1COc2ccc(-c3cc(-c4ccccc4)c4c(n3)-c3ccccc3OC4)cc2N1 nan
CHEMBL1317304 21565 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 2 1 4 5.3 O=C1COc2ccc(-c3cc(-c4ccccc4)c4c(n3)-c3ccccc3OC4)cc2N1 nan
1215486 21566 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 5.6 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1317307 21566 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 5.6 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1ccc(F)cc1 nan
4318326 21719 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 7 1 6 3.1 COc1ccc2nc(C)cc(SCC(NC(C)=O)C(=O)OC(C)C)c2c1 nan
CHEMBL1318910 21719 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 7 1 6 3.1 COc1ccc2nc(C)cc(SCC(NC(C)=O)C(=O)OC(C)C)c2c1 nan
621902 21723 10 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 5 0 5 3.5 CCSc1cnn(-c2ccccc2)c(=O)c1SCC nan
CHEMBL1318957 21723 10 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 5 0 5 3.5 CCSc1cnn(-c2ccccc2)c(=O)c1SCC nan
3152777 21849 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 4 2 7 5.0 Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccc(C)o4)C3c3cccc(O)c3)sc2c1 nan
CHEMBL1320029 21849 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 4 2 7 5.0 Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccc(C)o4)C3c3cccc(O)c3)sc2c1 nan
15990516 21969 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 4 5.1 COc1ccc2nc3sc(C(=O)NCCc4ccc(Cl)cc4)cc3cc2c1 nan
CHEMBL1321040 21969 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 4 5.1 COc1ccc2nc3sc(C(=O)NCCc4ccc(Cl)cc4)cc3cc2c1 nan
2158383 22198 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 6 1 6 2.1 CCOCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1323129 22198 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 6 1 6 2.1 CCOCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
864393 22258 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 3 4.1 Cc1cc(SCC(=O)NC2CCCCC2)nc2ccccc12 nan
CHEMBL1323679 22258 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 3 4.1 Cc1cc(SCC(=O)NC2CCCCC2)nc2ccccc12 nan
2138908 22286 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 4 5.0 CCOC(=O)c1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1323878 22286 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 4 5.0 CCOC(=O)c1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 nan
716947 22341 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 4 3.9 CCOc1ccc(-c2oc3ccc(C)cc3c(=O)c2O)cc1 nan
CHEMBL1324368 22341 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 4 3.9 CCOc1ccc(-c2oc3ccc(C)cc3c(=O)c2O)cc1 nan
2929091 22350 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 7 2.2 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCC1 nan
CHEMBL1324435 22350 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 7 2.2 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCC1 nan
16017079 22372 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 4 1 5 6.2 CCC(C(=O)Nc1cc(C(F)(F)F)ccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1324580 22372 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 4 1 5 6.2 CCC(C(=O)Nc1cc(C(F)(F)F)ccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O nan
6619868 22405 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 2 5 3.4 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2)CCS3)cc1 nan
CHEMBL1324841 22405 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 2 5 3.4 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2)CCS3)cc1 nan
135415532 22479 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 1 7 2.6 Cc1cc(O)nc(SCc2nc3ncccn3c2Br)n1 nan
CHEMBL1325556 22479 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 1 7 2.6 Cc1cc(O)nc(SCc2nc3ncccn3c2Br)n1 nan
1086445 22602 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 6 3.7 COc1ccc(-c2ccc3c(N)c(C(=O)NC(C)C)sc3n2)cc1OC nan
CHEMBL1326816 22602 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 6 3.7 COc1ccc(-c2ccc3c(N)c(C(=O)NC(C)C)sc3n2)cc1OC nan
5739163 22661 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 5 1 6 4.4 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(Br)c1)c1ccc2c(c1)OCO2 nan
CHEMBL1327274 22661 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 5 1 6 4.4 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(Br)c1)c1ccc2c(c1)OCO2 nan
2128134 22684 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 0 5 2.3 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cccnc2Cl)c1 nan
CHEMBL1327541 22684 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 0 5 2.3 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cccnc2Cl)c1 nan
5899385 22741 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 1 7 3.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3cccnc3)ccc2O1 nan
CHEMBL1327895 22741 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 1 7 3.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3cccnc3)ccc2O1 nan
3464558 22776 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 5 3.3 COc1ccc(S(=O)(=O)N2CCN(CC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)CC2)cc1 nan
CHEMBL1328124 22776 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 5 3.3 COc1ccc(S(=O)(=O)N2CCN(CC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)CC2)cc1 nan
1779937 22941 11 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 1 4 4.3 COc1ccc2sc3c(O)nc4ccccc4c3c2c1 nan
CHEMBL1329604 22941 11 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 1 4 4.3 COc1ccc2sc3c(O)nc4ccccc4c3c2c1 nan
16013718 23063 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 5 3.7 CCc1nonc1NC(=O)c1oc2ccc(Br)cc2c1C nan
CHEMBL1330644 23063 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 5 3.7 CCc1nonc1NC(=O)c1oc2ccc(Br)cc2c1C nan
2991043 23270 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 0.4 Cn1c(=O)c2c(nc(CN3CCc4ccccc4C3)n2CCCO)n(C)c1=O nan
CHEMBL1332170 23270 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 0.4 Cn1c(=O)c2c(nc(CN3CCc4ccccc4C3)n2CCCO)n(C)c1=O nan
1861856 23343 13 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 2 6 2.5 COc1cc2[nH]c(=S)n(NC(=O)c3ccccc3)c(=O)c2cc1OC nan
CHEMBL1332727 23343 13 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 2 6 2.5 COc1cc2[nH]c(=S)n(NC(=O)c3ccccc3)c(=O)c2cc1OC nan
5302228 23714 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 0 6 3.3 COc1ccc(N(C)S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccc(Cl)cn23)cc1 nan
CHEMBL1335569 23714 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 0 6 3.3 COc1ccc(N(C)S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccc(Cl)cn23)cc1 nan
16018981 23793 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 5 4.3 O=C(NCc1ccccc1Cl)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1336206 23793 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 5 4.3 O=C(NCc1ccccc1Cl)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
2807849 23815 69 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 217 2 1 3 3.2 CC(=O)c1sc(-c2ccccc2)cc1N nan
CHEMBL1336437 23815 69 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 217 2 1 3 3.2 CC(=O)c1sc(-c2ccccc2)cc1N nan
2222525 23835 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 7 3.0 CC(=O)c1sc2nc(SCC(=O)N3CCCCC3)nc(O)c2c1C nan
CHEMBL1336564 23835 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 7 3.0 CC(=O)c1sc2nc(SCC(=O)N3CCCCC3)nc(O)c2c1C nan
2844395 23894 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 4 2 3 1.3 CC(C)NC(=O)CC(=O)NN=C1CCCCC1 nan
CHEMBL1337153 23894 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 4 2 3 1.3 CC(C)NC(=O)CC(=O)NN=C1CCCCC1 nan
1480701 24006 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 2.0 COC(=O)c1nc2ccc(N3CCOCC3)cc2c(C)c1C(=O)OC nan
CHEMBL1338156 24006 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 2.0 COC(=O)c1nc2ccc(N3CCOCC3)cc2c(C)c1C(=O)OC nan
861738 24044 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 4 1 3 3.7 Cc1cc(SCC(=O)NC2CCCC2)nc2ccccc12 nan
CHEMBL1338383 24044 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 4 1 3 3.7 Cc1cc(SCC(=O)NC2CCCC2)nc2ccccc12 nan
4677074 24410 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 1 3 2.8 Sc1nc2ccccc2n2cccc12 nan
CHEMBL1341748 24410 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 1 3 2.8 Sc1nc2ccccc2n2cccc12 nan
2334933 24480 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 4 3.5 O=C(COC(=O)CSc1ccc2ccccc2c1Br)NC1CC1 nan
CHEMBL1342297 24480 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 4 3.5 O=C(COC(=O)CSc1ccc2ccccc2c1Br)NC1CC1 nan
650550 24545 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 0 6 3.4 COc1ccc(-c2nsc3c(N4CCCC4)ncnc23)cc1 nan
CHEMBL1342739 24545 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 0 6 3.4 COc1ccc(-c2nsc3c(N4CCCC4)ncnc23)cc1 nan
16445815 24706 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(F)cc2)s1 nan
CHEMBL1344160 24706 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(F)cc2)s1 nan
7190688 24732 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1344377 24732 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
3106500 24757 9 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 7 1.5 CC1=NN(C(N)=S)C(=O)C1N=Nc1ccc([N+](=O)[O-])cc1 nan
CHEMBL1344603 24757 9 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 7 1.5 CC1=NN(C(N)=S)C(=O)C1N=Nc1ccc([N+](=O)[O-])cc1 nan
20907339 24816 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 5 2.6 CCOCCCNC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 nan
CHEMBL1345074 24816 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 5 2.6 CCOCCCNC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 nan
6103434 24956 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 9 1 7 3.7 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1346374 24956 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 9 1 7 3.7 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
2122298 25091 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 5 1 5 2.7 CC(=O)c1sc(NC(=O)COc2ccccc2)nc1C nan
CHEMBL1347404 25091 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 5 1 5 2.7 CC(=O)c1sc(NC(=O)COc2ccccc2)nc1C nan
899068 25139 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 1 1 6 3.6 CSc1nc(S)c2c3c(sc2n1)COC(C)(C)C3 nan
CHEMBL1347767 25139 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 1 1 6 3.6 CSc1nc(S)c2c3c(sc2n1)COC(C)(C)C3 nan
1481616 25205 21 None -15 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 5 0 4 4.3 COc1cccc(CSc2nc3ccccc3cc2C=O)c1 nan
CHEMBL1348389 25205 21 None -15 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 5 0 4 4.3 COc1cccc(CSc2nc3ccccc3cc2C=O)c1 nan
1378026 25225 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 5 4.2 COc1ccc(NC(=O)c2ccc(C(=O)c3cc(OC)ccc3OC)cc2)cc1 nan
CHEMBL1348606 25225 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 5 4.2 COc1ccc(NC(=O)c2ccc(C(=O)c3cc(OC)ccc3OC)cc2)cc1 nan
2205361 25228 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 4 3 9 2.3 COC(=O)c1sc(N=C(S)NNC(=O)c2c(Br)c(C)nn2C)c(C(=O)OC)c1C nan
CHEMBL1348642 25228 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 4 3 9 2.3 COC(=O)c1sc(N=C(S)NNC(=O)c2c(Br)c(C)nn2C)c(C(=O)OC)c1C nan
2084877 25242 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 1 5 3.8 COCCNC(=O)CSc1cc(-c2ccccc2)c2ccc(OC)cc2n1 nan
CHEMBL1348812 25242 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 1 5 3.8 COCCNC(=O)CSc1cc(-c2ccccc2)c2ccc(OC)cc2n1 nan
1256964 25248 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 4 1 4 5.1 O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2ccc(Br)cc12 nan
CHEMBL1348841 25248 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 4 1 4 5.1 O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2ccc(Br)cc12 nan
3783556 25328 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.0 C=CCN1C(=O)NC(=O)/C(=C\Nc2c(C)n(C)n(-c3ccccc3)c2=O)C1=O nan
CHEMBL1349443 25328 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.0 C=CCN1C(=O)NC(=O)/C(=C\Nc2c(C)n(C)n(-c3ccccc3)c2=O)C1=O nan
24746879 25341 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 0 6 3.5 COC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1349543 25341 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 0 6 3.5 COC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
4831863 25421 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 9 0.5 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)Cn1nnc2ccccc2c1=O nan
CHEMBL1350232 25421 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 9 0.5 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)Cn1nnc2ccccc2c1=O nan
663661 25457 16 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 5 4.5 c1ccc2[nH]c(CSc3ncnc4c3oc3ccccc34)nc2c1 nan
CHEMBL1350581 25457 16 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 5 4.5 c1ccc2[nH]c(CSc3ncnc4c3oc3ccccc34)nc2c1 nan
2881707 25586 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 5 3.2 Cc1nnc(Nc2ccc(C(=O)N3CCOCC3)cc2)c2ccccc12 nan
CHEMBL1351647 25586 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 5 3.2 Cc1nnc(Nc2ccc(C(=O)N3CCOCC3)cc2)c2ccccc12 nan
5308898 25603 63 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 1 1 3 2.4 CCc1cc(=O)oc2cc(C)cc(O)c12 nan
CHEMBL1351746 25603 63 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 1 1 3 2.4 CCc1cc(=O)oc2cc(C)cc(O)c12 nan
2802516 25658 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 1 4 3.2 Sc1nc(-c2ccccc2)n(-c2ccccc2)n1 nan
CHEMBL1352266 25658 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 1 4 3.2 Sc1nc(-c2ccccc2)n(-c2ccccc2)n1 nan
1435022 25748 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 6 4.3 CCc1nc(SCC(=O)Nc2nc3c(s2)CCCC3)c2ccccc2n1 nan
CHEMBL1352936 25748 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 6 4.3 CCc1nc(SCC(=O)Nc2nc3c(s2)CCCC3)c2ccccc2n1 nan
7285290 25782 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 2 3.5 Cc1nc(-c2ccc(Br)cc2)ccc1C(=O)O nan
CHEMBL1353200 25782 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 2 3.5 Cc1nc(-c2ccc(Br)cc2)ccc1C(=O)O nan
15989677 25945 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 9 1 9 3.5 COc1cc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc(OC)c1 nan
CHEMBL1354335 25945 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 9 1 9 3.5 COc1cc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc(OC)c1 nan
16030401 25981 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 8 1 4 5.0 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCc2ccccc2)cc1 nan
CHEMBL1354835 25981 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 8 1 4 5.0 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCc2ccccc2)cc1 nan
16010860 25984 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 6 2.8 CCc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1 nan
CHEMBL1354858 25984 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 6 2.8 CCc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1 nan
15988167 26047 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 2.9 COc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3ccccc32)c1 nan
CHEMBL1355668 26047 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 2.9 COc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3ccccc32)c1 nan
16024817 26147 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 1 4 5.2 O=C(Nc1ccccc1Cl)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1356900 26147 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 1 4 5.2 O=C(Nc1ccccc1Cl)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
1165987 26253 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 6 4.0 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCC(C)C)n2)cc1OC nan
CHEMBL1358322 26253 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 6 4.0 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCC(C)C)n2)cc1OC nan
1003453 26268 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 2 5 5.6 Nc1c(C(=O)Nc2ccccc2Br)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1358598 26268 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 2 5 5.6 Nc1c(C(=O)Nc2ccccc2Br)sc2nc(-c3cccs3)ccc12 nan
663400 26315 13 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.8 O=C(CSc1ncnc2c1oc1ccccc12)Nc1cccc(Cl)c1 nan
CHEMBL1359009 26315 13 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.8 O=C(CSc1ncnc2c1oc1ccccc12)Nc1cccc(Cl)c1 nan
5104589 26396 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 3 6.6 O=C(Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1)c1ccc2ccccc2c1 nan
CHEMBL1359625 26396 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 3 6.6 O=C(Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1)c1ccc2ccccc2c1 nan
4438847 26524 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 1.1 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1cccc[n+]1[O-] nan
CHEMBL1360781 26524 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 1.1 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1cccc[n+]1[O-] nan
15989315 26526 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 563 10 1 7 4.6 COc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4ccccc4n(Cc4cccc(C)c4)c3=O)cc2)cc1OC nan
CHEMBL1360796 26526 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 563 10 1 7 4.6 COc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4ccccc4n(Cc4cccc(C)c4)c3=O)cc2)cc1OC nan
15991495 26562 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 3 5 3.9 O=C(O)Cc1sc(Nc2ccc(C(=O)O)cc2)nc1-c1ccccc1 nan
CHEMBL1361126 26562 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 3 5 3.9 O=C(O)Cc1sc(Nc2ccc(C(=O)O)cc2)nc1-c1ccccc1 nan
2816171 26610 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 8 1.3 CCOC(=O)c1nnn2c1nc(N1CCOCC1)c1ccccc12 nan
CHEMBL1361598 26610 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 8 1.3 CCOC(=O)c1nnn2c1nc(N1CCOCC1)c1ccccc12 nan
6238059 26681 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 10 2 6 2.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2ccc(F)cc2)cc1 nan
CHEMBL1362160 26681 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 10 2 6 2.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2ccc(F)cc2)cc1 nan
15988824 26697 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 7 4.2 COc1ccc(-c2cc(C(=O)Nc3ccn(Cc4ccc(C)cc4)n3)no2)cc1OC nan
CHEMBL1362337 26697 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 7 4.2 COc1ccc(-c2cc(C(=O)Nc3ccn(Cc4ccc(C)cc4)n3)no2)cc1OC nan
6625370 27017 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 1 7 2.2 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3cccc(F)c3)sc2n1 nan
CHEMBL1365096 27017 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 1 7 2.2 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3cccc(F)c3)sc2n1 nan
1315619 27050 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 3 5 4.3 O=C(Nc1ccccc1C(=O)Nc1ccccc1C(=O)NCc1ccco1)c1ccco1 nan
CHEMBL1365331 27050 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 3 5 4.3 O=C(Nc1ccccc1C(=O)Nc1ccccc1C(=O)NCc1ccco1)c1ccco1 nan
2138525 27069 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 7 4.6 Cc1ccc(-c2nnn3c2nc(NCc2ccc4c(c2)OCO4)c2ccccc23)cc1 nan
CHEMBL1365483 27069 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 7 4.6 Cc1ccc(-c2nnn3c2nc(NCc2ccc4c(c2)OCO4)c2ccccc23)cc1 nan
5068934 27118 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 3 3.0 O=C(CCS(=O)(=O)Cc1cccc(Cl)c1)NCCc1ccccc1 nan
CHEMBL1365953 27118 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 3 3.0 O=C(CCS(=O)(=O)Cc1cccc(Cl)c1)NCCc1ccccc1 nan
7190319 27120 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 3 0 6 3.0 CCSc1ccc2nnc(-c3cccs3)n2n1 nan
CHEMBL1365969 27120 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 3 0 6 3.0 CCSc1ccc2nnc(-c3cccs3)n2n1 nan
16194607 27298 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 10 1 7 1.7 CCN(CC)CCCNC(=O)Cn1cnc2ccc(S(=O)(=O)N3CCC(C)CC3)cc2c1=O nan
CHEMBL1367480 27298 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 10 1 7 1.7 CCN(CC)CCCNC(=O)Cn1cnc2ccc(S(=O)(=O)N3CCC(C)CC3)cc2c1=O nan
16033554 27429 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 2 4 1.7 CC(=O)Nc1ccc(NC(=O)CN2C(=O)CN(C)C(=O)c3ccccc32)cc1 nan
CHEMBL1368494 27429 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 2 4 1.7 CC(=O)Nc1ccc(NC(=O)CN2C(=O)CN(C)C(=O)c3ccccc32)cc1 nan
16009410 27520 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 5.2 CCC(CC)c1nn2c(=O)cc(COc3ccc(NC(=O)c4ccccc4C)cc3)nc2s1 nan
CHEMBL1369161 27520 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 5.2 CCC(CC)c1nn2c(=O)cc(COc3ccc(NC(=O)c4ccccc4C)cc3)nc2s1 nan
20880788 27680 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 7 3.4 CC1CCCC(C)N1CCNC(=O)CCc1nnc2n(Cc3ccccc3)c(=O)c3ccccc3n12 nan
CHEMBL1370306 27680 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 7 3.4 CC1CCCC(C)N1CCNC(=O)CCc1nnc2n(Cc3ccccc3)c(=O)c3ccccc3n12 nan
2622707 27750 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 4 0 6 2.9 O=[N+]([O-])c1cccc(CSc2nnc3ccccn23)c1 nan
CHEMBL1370729 27750 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 4 0 6 2.9 O=[N+]([O-])c1cccc(CSc2nnc3ccccn23)c1 nan
3178485 27803 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCn1c(SCC(=O)N2CCCCC2C)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1371157 27803 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCn1c(SCC(=O)N2CCCCC2C)nc2c1c(=O)n(C)c(=O)n2C nan
2155682 27994 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 4 0 5 3.1 CC1CCN(C(=O)CSc2nnc(-c3ccccc3)o2)CC1 nan
CHEMBL1372587 27994 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 4 0 5 3.1 CC1CCN(C(=O)CSc2nnc(-c3ccccc3)o2)CC1 nan
2965534 28016 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 5 5.1 CCOc1ccc(-c2cc(C(=O)NCCCn3ccnc3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1372738 28016 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 5 5.1 CCOc1ccc(-c2cc(C(=O)NCCCn3ccnc3)c3cc(Br)ccc3n2)cc1 nan
2562079 28192 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 3 1 5 2.6 O=C(O)CSc1ncnc2c1oc1ccccc12 nan
CHEMBL1373813 28192 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 3 1 5 2.6 O=C(O)CSc1ncnc2c1oc1ccccc12 nan
2478421 28347 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 1 7 0.8 CC1(C)NC(=O)N(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)C1=O nan
CHEMBL1374872 28347 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 1 7 0.8 CC1(C)NC(=O)N(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)C1=O nan
3122786 28416 19 None -10 4 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 4 5.1 COc1ccc(C2CC(c3cccs3)=NN2c2ccccc2)cc1 nan
CHEMBL1375375 28416 19 None -10 4 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 4 5.1 COc1ccc(C2CC(c3cccs3)=NN2c2ccccc2)cc1 nan
4077805 28498 30 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 5 3.9 C=CCn1c(=S)[nH]c2scc(-c3ccc(C)o3)c2c1=O nan
CHEMBL1376201 28498 30 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 5 3.9 C=CCn1c(=S)[nH]c2scc(-c3ccc(C)o3)c2c1=O nan
2815476 28581 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 4 4.6 O=S(=O)(Nc1ccccc1C(F)(F)F)c1ccc(-c2ccccn2)s1 nan
CHEMBL1376936 28581 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 4 4.6 O=S(=O)(Nc1ccccc1C(F)(F)F)c1ccc(-c2ccccn2)s1 nan
16016416 28617 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 5 3.6 Cc1cc(O)c(CN2CCN(c3ccc(F)cc3)CC2)c2oc(=O)cc(C)c12 nan
CHEMBL1377283 28617 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 5 3.6 Cc1cc(O)c(CN2CCN(c3ccc(F)cc3)CC2)c2oc(=O)cc(C)c12 nan
2400757 28651 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 2.1 O=C(CNC(=O)c1cccc(F)c1)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1377678 28651 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 2.1 O=C(CNC(=O)c1cccc(F)c1)OCc1cc(=O)n2cc(Br)ccc2n1 nan
2864532 28704 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 1 3 4.2 CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccccc2)C1c1ccccc1 nan
CHEMBL1378083 28704 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 1 3 4.2 CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccccc2)C1c1ccccc1 nan
3522811 28760 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 8 0.8 Cc1nc(SCC(=O)NCCc2ccccc2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1378692 28760 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 8 0.8 Cc1nc(SCC(=O)NCCc2ccccc2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
4647380 28835 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 12 1 9 0.8 COCCN(CCOC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(COC)o2)cc1 nan
CHEMBL1379293 28835 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 12 1 9 0.8 COCCN(CCOC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(COC)o2)cc1 nan
5904589 28937 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 2 6 3.9 O=C(C1=C(O)C(=O)N(Cc2ccccc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1380259 28937 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 2 6 3.9 O=C(C1=C(O)C(=O)N(Cc2ccccc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
2768996 28986 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 1 6 2.2 O=c1c2ccccc2nc(-c2ccc([N+](=O)[O-])cc2)n1O nan
CHEMBL1380557 28986 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 1 6 2.2 O=c1c2ccccc2nc(-c2ccc([N+](=O)[O-])cc2)n1O nan
2815634 29002 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 4 5.8 O=C(Nc1ccc(F)cc1)Nc1sccc1-c1nc2ccccc2s1 nan
CHEMBL1380666 29002 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 4 5.8 O=C(Nc1ccc(F)cc1)Nc1sccc1-c1nc2ccccc2s1 nan
3604840 29012 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 5 3.7 COc1cccc(-c2cc(C(=O)Nc3cccnc3Cl)no2)c1 nan
CHEMBL1380782 29012 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 5 3.7 COc1cccc(-c2cc(C(=O)Nc3cccnc3Cl)no2)c1 nan
723113 29032 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 2 4 4 3.9 Nc1ccc2[nH]c(-c3ccc(-c4nc5cc(N)ccc5[nH]4)cc3)nc2c1 nan
CHEMBL1380889 29032 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 2 4 4 3.9 Nc1ccc2[nH]c(-c3ccc(-c4nc5cc(N)ccc5[nH]4)cc3)nc2c1 nan
866607 29085 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.8 CC1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1381324 29085 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.8 CC1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
1247739 29265 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 6 4.6 Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Nc1nnc(C(F)(F)F)s1 nan
CHEMBL1382928 29265 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 6 4.6 Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Nc1nnc(C(F)(F)F)s1 nan
4908738 29287 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 7 1 8 4.6 CCCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
CHEMBL1383134 29287 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 7 1 8 4.6 CCCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
4196061 29453 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 10 2 5 3.4 CCCCCNC(=O)c1ccc2c(=O)n(CCCOCC)c(=S)[nH]c2c1 nan
CHEMBL1384631 29453 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 10 2 5 3.4 CCCCCNC(=O)c1ccc2c(=O)n(CCCOCC)c(=S)[nH]c2c1 nan
1392125 29540 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 2 6 2.0 O=C1NC(=S)N(Cc2ccc(F)cc2)C(=O)/C1=C/NCc1ccc2c(c1)OCO2 nan
CHEMBL1385415 29540 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 2 6 2.0 O=C1NC(=S)N(Cc2ccc(F)cc2)C(=O)/C1=C/NCc1ccc2c(c1)OCO2 nan
20876328 29637 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 5 3.3 CN1CCN(CCCNC(=O)c2ccc3c(c2)N(Cc2ccc(F)cc2)CCS3)CC1 nan
CHEMBL1386262 29637 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 5 3.3 CN1CCN(CCCNC(=O)c2ccc3c(c2)N(Cc2ccc(F)cc2)CCS3)CC1 nan
17584980 29679 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 3 1 7 2.2 Cc1cc(O)c2c(C)c(CC(=O)N3CCN(C(=O)C4COc5ccccc5O4)CC3)c(=O)oc2c1 nan
CHEMBL1386530 29679 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 3 1 7 2.2 Cc1cc(O)c2c(C)c(CC(=O)N3CCN(C(=O)C4COc5ccccc5O4)CC3)c(=O)oc2c1 nan
3254139 29713 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.8 CSc1nc(SC(C)C(=O)O)c2c3c(sc2n1)COC(C)(C)C3 nan
CHEMBL1386773 29713 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.8 CSc1nc(SC(C)C(=O)O)c2c3c(sc2n1)COC(C)(C)C3 nan
3220391 29764 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 7 1 6 2.1 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCCOC nan
CHEMBL1387168 29764 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 7 1 6 2.1 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCCOC nan
16189864 29797 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 0 5 4.4 O=C(c1ccc(C(F)(F)F)cc1)C1CCCN(Cc2cccn2-c2ncccn2)C1 nan
CHEMBL1387467 29797 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 0 5 4.4 O=C(c1ccc(C(F)(F)F)cc1)C1CCCN(Cc2cccn2-c2ncccn2)C1 nan
899135 29840 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 1 3 3.2 NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1387789 29840 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 1 3 3.2 NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
2360761 29841 26 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 1 5 2.5 COc1ccc2c(C)cc3nnc(S)n3c2c1 nan
CHEMBL1387791 29841 26 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 1 5 2.5 COc1ccc2c(C)cc3nnc(S)n3c2c1 nan
2377721 29884 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 0 6 3.9 Cc1cc(C)nc(Sc2ncnc3c2oc2ccccc23)n1 nan
CHEMBL1388175 29884 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 0 6 3.9 Cc1cc(C)nc(Sc2ncnc3c2oc2ccccc23)n1 nan
3303130 30048 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 6 6.0 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Oc3ccccc3)c2)n1 nan
CHEMBL1389429 30048 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 6 6.0 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Oc3ccccc3)c2)n1 nan
5047557 30094 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 2 5 2.7 COC(=O)c1cc(C)sc1NC(=O)C1C2C=CC(CC2)C1C(=O)O nan
CHEMBL1389758 30094 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 2 5 2.7 COC(=O)c1cc(C)sc1NC(=O)C1C2C=CC(CC2)C1C(=O)O nan
671729 30157 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 4 3.8 O=C(Nc1ccc2c(c1)C(=O)N(c1ccccc1)C2=O)c1cccs1 nan
CHEMBL1390374 30157 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 4 3.8 O=C(Nc1ccc2c(c1)C(=O)N(c1ccccc1)C2=O)c1cccs1 nan
576025 30178 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 0 0 4 1.6 O=c1c2ccccc2c(=O)n2n1Cc1ccccc1C2 nan
CHEMBL1390537 30178 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 0 0 4 1.6 O=c1c2ccccc2c(=O)n2n1Cc1ccccc1C2 nan
1245900 30231 11 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 6 3.8 CCSc1nnc(NC(=O)c2cc3c(s2)CCCC3)s1 nan
CHEMBL1391017 30231 11 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 6 3.8 CCSc1nnc(NC(=O)c2cc3c(s2)CCCC3)s1 nan
5260648 30255 37 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 1 1 3 2.1 Cc1cc(Br)cn2cc(C(=O)O)nc12 nan
CHEMBL1391195 30255 37 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 1 1 3 2.1 Cc1cc(Br)cn2cc(C(=O)O)nc12 nan
6619983 30341 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 0 7 2.4 COC(=O)C(C)Sc1ccc2nnc(-c3ccccc3)n2n1 nan
CHEMBL1391987 30341 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 0 7 2.4 COC(=O)C(C)Sc1ccc2nnc(-c3ccccc3)n2n1 nan
3236381 30440 3 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 8 2.5 CCOC(=O)c1sc2ncnc(N3CCN(C(=O)OCC)CC3)c2c1C nan
CHEMBL1392800 30440 3 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 8 2.5 CCOC(=O)c1sc2ncnc(N3CCN(C(=O)OCC)CC3)c2c1C nan
135414599 30538 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 4 0.2 O=C1CC2C(=O)NCCN2C(NC(=O)c2ccc(Cl)cc2)=N1 nan
CHEMBL1393609 30538 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 4 0.2 O=C1CC2C(=O)NCCN2C(NC(=O)c2ccc(Cl)cc2)=N1 nan
950424 30636 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 0 7 1.6 CCN1CCN(c2nc3c(C)cccn3c(=O)c2C=C(C#N)C#N)CC1 nan
CHEMBL1394651 30636 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 0 7 1.6 CCN1CCN(c2nc3c(C)cccn3c(=O)c2C=C(C#N)C#N)CC1 nan
1689018 30650 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.2 CCOC(=O)c1sc2ncn(CC(=O)Nc3cc(C)cc(C)c3)c(=O)c2c1C nan
CHEMBL1394885 30650 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.2 CCOC(=O)c1sc2ncn(CC(=O)Nc3cc(C)cc(C)c3)c(=O)c2c1C nan
8087252 30714 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 0 5 4.3 COc1cccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)c1 nan
CHEMBL1395507 30714 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 0 5 4.3 COc1cccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)c1 nan
16009438 30723 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1 nan
CHEMBL1395616 30723 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1 nan
16017578 30758 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)cc1 nan
CHEMBL1396189 30758 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)cc1 nan
24819156 30775 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 0 6 6.1 COc1ccc(-c2oc3ccc(N4CCOCC4)cc3c2/C=C/c2ccc(OC)c(OC)c2)cc1 nan
CHEMBL1396464 30775 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 0 6 6.1 COc1ccc(-c2oc3ccc(N4CCOCC4)cc3c2/C=C/c2ccc(OC)c(OC)c2)cc1 nan
16022449 30812 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 4 4.9 CC(C)Oc1ccc(CNC(=O)c2cc3cccc4c3n2CC(C)S4)cc1 nan
CHEMBL1396952 30812 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 4 4.9 CC(C)Oc1ccc(CNC(=O)c2cc3cccc4c3n2CC(C)S4)cc1 nan
2017205 30832 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 2 6 5.8 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C(F)(F)F)cc4)sc3n2)cc1OC nan
CHEMBL1397215 30832 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 2 6 5.8 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C(F)(F)F)cc4)sc3n2)cc1OC nan
16019456 30901 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 8 2.5 COc1cc(NS(=O)(=O)c2c(C)nc3sc(C)c(C)n3c2=O)cc(OC)c1 nan
CHEMBL1398166 30901 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 8 2.5 COc1cc(NS(=O)(=O)c2c(C)nc3sc(C)c(C)n3c2=O)cc(OC)c1 nan
2964735 30942 11 None -3 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 7 1 9 4.5 COc1cccc(C2C(C(=O)c3cc4cccc(OC)c4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
CHEMBL1398596 30942 11 None -3 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 7 1 9 4.5 COc1cccc(C2C(C(=O)c3cc4cccc(OC)c4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
16012160 30960 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 7 2.0 Cc1cc(=O)n2nc(N(C)CC(=O)NCc3cccc(Br)c3)sc2n1 nan
CHEMBL1398785 30960 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 7 2.0 Cc1cc(=O)n2nc(N(C)CC(=O)NCc3cccc(Br)c3)sc2n1 nan
20888752 31057 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 7 1 9 1.2 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
CHEMBL1399722 31057 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 7 1 9 1.2 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
7997207 31099 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 5 3.3 Cc1ccc(NC(=O)COC(=O)c2ccc(-n3cccn3)cc2)cc1C nan
CHEMBL1400115 31099 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 5 3.3 Cc1ccc(NC(=O)COC(=O)c2ccc(-n3cccn3)cc2)cc1C nan
2874407 31123 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 7 5.0 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccccc3c2=O)C2=C(O)CC(C)(C)CC2=N1 nan
CHEMBL1400295 31123 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 7 5.0 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccccc3c2=O)C2=C(O)CC(C)(C)CC2=N1 nan
2157035 31208 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 5.0 Cc1ccc(-c2nc(S(=O)(=O)c3ccccc3)c(SCC(=O)NC3CCCCC3)o2)cc1 nan
CHEMBL1401131 31208 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 5.0 Cc1ccc(-c2nc(S(=O)(=O)c3ccccc3)c(SCC(=O)NC3CCCCC3)o2)cc1 nan
5389771 31211 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 9 1 6 2.9 C=CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOC)C2c2cccnc2)cc1 nan
CHEMBL1401159 31211 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 9 1 6 2.9 C=CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOC)C2c2cccnc2)cc1 nan
20876293 31401 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 5 3.9 CCN1CCN(CCCNC(=O)c2ccc3c(c2)N(Cc2ccc(C)cc2)CCS3)CC1 nan
CHEMBL1402721 31401 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 5 3.9 CCN1CCN(CCCNC(=O)c2ccc3c(c2)N(Cc2ccc(C)cc2)CCS3)CC1 nan
16025411 31404 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 7 3.3 COC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1cccc(F)c1)S2(=O)=O nan
CHEMBL1402769 31404 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 7 3.3 COC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1cccc(F)c1)S2(=O)=O nan
1091654 31511 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 7 2 5 4.5 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)COc1ccc(Cl)cc1C nan
CHEMBL1403849 31511 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 7 2 5 4.5 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)COc1ccc(Cl)cc1C nan
2405342 31647 24 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 2.9 O=S(=O)(Nc1nc2cc3c(cc2nc1Cl)OCCO3)c1ccccc1 nan
CHEMBL1405208 31647 24 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 2.9 O=S(=O)(Nc1nc2cc3c(cc2nc1Cl)OCCO3)c1ccccc1 nan
16018264 31682 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 6 5.7 CCOC(=O)c1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
CHEMBL1405564 31682 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 6 5.7 CCOC(=O)c1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
3258366 31791 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 1 2 6 3.5 CCC1(C)Cc2c(sc3nc(S)nc(S)c23)CO1 nan
CHEMBL1406514 31791 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 1 2 6 3.5 CCC1(C)Cc2c(sc3nc(S)nc(S)c23)CO1 nan
5739089 31839 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.7 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(F)c1)c1ccc2c(c1)OCO2 nan
CHEMBL1407014 31839 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.7 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(F)c1)c1ccc2c(c1)OCO2 nan
20877853 32052 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 0 5 3.7 CCOC(=O)C1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
CHEMBL1408512 32052 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 0 5 3.7 CCOC(=O)C1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
704023 32205 42 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 4 3.6 Sc1ncnc2sc(-c3ccccc3)cc12 nan
CHEMBL1409776 32205 42 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 4 3.6 Sc1ncnc2sc(-c3ccccc3)cc12 nan
4197372 32224 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.5 O=C(Nc1nc(-c2cccs2)c(C(=O)C(F)(F)F)s1)c1ccco1 nan
CHEMBL1409901 32224 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.5 O=C(Nc1nc(-c2cccs2)c(C(=O)C(F)(F)F)s1)c1ccco1 nan
1348850 32237 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 5 5.3 COc1ccc(OCC(=O)Nc2cc(-c3nc4ccccc4s3)ccc2C)cc1 nan
CHEMBL1409994 32237 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 5 5.3 COc1ccc(OCC(=O)Nc2cc(-c3nc4ccccc4s3)ccc2C)cc1 nan
6472686 32266 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 5 1 5 1.5 COc1cccc2cc(C(=O)NCCN3CCOCC3)oc12 nan
CHEMBL1410184 32266 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 5 1 5 1.5 COc1cccc2cc(C(=O)NCCN3CCOCC3)oc12 nan
16019689 32342 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 10 1 8 2.9 COCCCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
CHEMBL1410849 32342 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 10 1 8 2.9 COCCCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
16025704 32429 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 7 5.5 COc1ccc(OC)c(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
CHEMBL1411590 32429 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 7 5.5 COc1ccc(OC)c(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
15988174 32530 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 2 4 3.0 Cc1ccc(CCNC(=O)c2ccc3c(=O)n(-c4ccccc4)c(=O)[nH]c3c2)cc1 nan
CHEMBL1412411 32530 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 2 4 3.0 Cc1ccc(CCNC(=O)c2ccc3c(=O)n(-c4ccccc4)c(=O)[nH]c3c2)cc1 nan
972224 32583 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 2 5 3.8 CCc1c(C)sc(N=C(S)Nc2cccnc2)c1C(=O)OC nan
CHEMBL1412818 32583 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 2 5 3.8 CCc1c(C)sc(N=C(S)Nc2cccnc2)c1C(=O)OC nan
16018140 32593 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 2 4.5 Cn1cc(CCCC(=O)NCc2ccccc2Cl)c2ccccc21 nan
CHEMBL1412876 32593 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 2 4.5 Cn1cc(CCCC(=O)NCc2ccccc2Cl)c2ccccc21 nan
646994 32629 5 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 3.4 Cc1ccc(S(=O)(=O)N(Cc2cc3cc4c(cc3nc2O)OCCO4)CC2CCCO2)cc1 nan
CHEMBL1413144 32629 5 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 3.4 Cc1ccc(S(=O)(=O)N(Cc2cc3cc4c(cc3nc2O)OCCO4)CC2CCCO2)cc1 nan
16018722 32667 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 4.1 Cc1ccc(C)c(NC(=O)CSc2nnc(C)n3c2cc2occc23)c1 nan
CHEMBL1413449 32667 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 4.1 Cc1ccc(C)c(NC(=O)CSc2nnc(C)n3c2cc2occc23)c1 nan
4149556 32703 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 3 4.3 CC(C)(C)C(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccccc1F nan
CHEMBL1413747 32703 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 3 4.3 CC(C)(C)C(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccccc1F nan
16018046 32822 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 4 3.8 O=C(CCn1c(=O)c2cccn2c2ccc(F)cc21)NCCc1ccccc1Cl nan
CHEMBL1414743 32822 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 4 3.8 O=C(CCn1c(=O)c2cccn2c2ccc(F)cc21)NCCc1ccccc1Cl nan
16187993 32879 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)NCc1ccccn1)C(=O)CO2 nan
CHEMBL1415247 32879 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)NCc1ccccn1)C(=O)CO2 nan
2910208 33044 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 6 3.3 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(F)cc1)c1ccco1 nan
CHEMBL1416738 33044 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 6 3.3 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(F)cc1)c1ccco1 nan
5014048 33088 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 3 5.9 Cc1ccc(CCNC(=O)c2cc(Nc3ccc(C)c(C)c3)nc3ccccc23)cc1 nan
CHEMBL1417106 33088 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 3 5.9 Cc1ccc(CCNC(=O)c2cc(Nc3ccc(C)c(C)c3)nc3ccccc23)cc1 nan
8901980 33119 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 5 4.1 CCOC(=O)Nc1ccc2c(CN(C)Cc3ccc(F)cc3)cc(=O)oc2c1 nan
CHEMBL1417351 33119 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 5 4.1 CCOC(=O)Nc1ccc2c(CN(C)Cc3ccc(F)cc3)cc(=O)oc2c1 nan
2911345 33232 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 5 4.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Br)cc2)o1 nan
3999653 33232 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 5 4.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Br)cc2)o1 nan
CHEMBL1418370 33232 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 5 4.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Br)cc2)o1 nan
1388232 33304 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 1 1 4 5.2 Cc1cccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCc2ccccc2-4)c1 nan
CHEMBL1418971 33304 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 1 1 4 5.2 Cc1cccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCc2ccccc2-4)c1 nan
2077572 33350 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 1 6 1.9 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1419336 33350 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 1 6 1.9 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2cc(Br)ccc2n1 nan
2370216 33687 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 3 0 3 4.2 O=C(COc1c(Br)cc(Br)c2cccnc12)N1CCCCC1 nan
CHEMBL1422190 33687 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 3 0 3 4.2 O=C(COc1c(Br)cc(Br)c2cccnc12)N1CCCCC1 nan
2035062 33710 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 5 2.6 CC(=O)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
CHEMBL1422374 33710 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 5 2.6 CC(=O)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
16187581 33713 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 8 0 7 2.8 C=CCN(Cc1nc(-c2cc(OC)ccc2OC)oc1C)C1CCS(=O)(=O)C1 nan
CHEMBL1422392 33713 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 8 0 7 2.8 C=CCN(Cc1nc(-c2cc(OC)ccc2OC)oc1C)C1CCS(=O)(=O)C1 nan
5931057 33769 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 7 4.0 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1422871 33769 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 7 4.0 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 nan
1609403 33868 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 0 5 4.7 CCCCn1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Br)cc2)c1 nan
CHEMBL1423632 33868 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 0 5 4.7 CCCCn1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Br)cc2)c1 nan
2308387 33903 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 0 8 2.6 Cc1c(CCOC(=O)c2cc([N+](=O)[O-])ccc2Cl)sc[n+]1CCCCS(=O)(=O)[O-] nan
CHEMBL1423887 33903 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 0 8 2.6 Cc1c(CCOC(=O)c2cc([N+](=O)[O-])ccc2Cl)sc[n+]1CCCCS(=O)(=O)[O-] nan
3546539 33968 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 2 4 1.2 O=C1NC(=S)N(C2CC2)C(=O)/C1=C/NCc1ccc(F)cc1 nan
CHEMBL1424530 33968 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 2 4 1.2 O=C1NC(=S)N(C2CC2)C(=O)/C1=C/NCc1ccc(F)cc1 nan
16192280 34114 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 4 4.2 CSc1ccc(C(=O)C2CCCN(C(=O)c3ccsc3)C2)cc1 nan
CHEMBL1425858 34114 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 4 4.2 CSc1ccc(C(=O)C2CCCN(C(=O)c3ccsc3)C2)cc1 nan
1229909 34390 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 6 2.7 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)n1 nan
CHEMBL1428119 34390 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 6 2.7 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)n1 nan
20903654 34541 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 0 9 1.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)CC1 nan
CHEMBL1429390 34541 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 0 9 1.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)CC1 nan
3259805 34546 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 7 1.9 Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)COC(=O)c1cccnc1Cl nan
CHEMBL1429423 34546 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 7 1.9 Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)COC(=O)c1cccnc1Cl nan
18562990 34593 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 7 2.0 O=C(NCCc1nnc2ccc(SCC(=O)N3CCCC3)nn12)c1ccc(F)cc1 nan
CHEMBL1429771 34593 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 7 2.0 O=C(NCCc1nnc2ccc(SCC(=O)N3CCCC3)nn12)c1ccc(F)cc1 nan
11834440 34612 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 4.9 CC(C)(C)c1ccc(/C(O)=C(/C([S-])=NCc2ccco2)[n+]2ccccc2)cc1 nan
4030418 34612 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 4.9 CC(C)(C)c1ccc(/C(O)=C(/C([S-])=NCc2ccco2)[n+]2ccccc2)cc1 nan
CHEMBL1429883 34612 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 4.9 CC(C)(C)c1ccc(/C(O)=C(/C([S-])=NCc2ccco2)[n+]2ccccc2)cc1 nan
3402414 34633 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -2.3 Cn1c(N)c(C(=O)COC(=O)C2=NNC(=O)CC2)c(=O)n(C)c1=O nan
CHEMBL1430091 34633 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -2.3 Cn1c(N)c(C(=O)COC(=O)C2=NNC(=O)CC2)c(=O)n(C)c1=O nan
2578265 34637 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 1 6 1.8 CC1CCC2(CC1)NC(=O)N(Cc1cc(=O)n3ccsc3n1)C2=O nan
CHEMBL1430109 34637 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 1 6 1.8 CC1CCC2(CC1)NC(=O)N(Cc1cc(=O)n3ccsc3n1)C2=O nan
4987698 34908 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 2 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(O)c1)c1cc2ccccc2o1 nan
CHEMBL1432401 34908 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 2 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(O)c1)c1cc2ccccc2o1 nan
657881 34919 10 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 2 1 5 1.9 CCOC(=O)c1c(C)nsc1S nan
CHEMBL1432472 34919 10 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 2 1 5 1.9 CCOC(=O)c1c(C)nsc1S nan
5123174 34939 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 5 3.3 COCCCn1c(=S)[nH]c2c(sc3ccccc32)c1=O nan
CHEMBL1432655 34939 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 5 3.3 COCCCn1c(=S)[nH]c2c(sc3ccccc32)c1=O nan
16019017 35088 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 5 3.9 Cc1cccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)c1 nan
CHEMBL1434147 35088 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 5 3.9 Cc1cccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)c1 nan
3566323 35136 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 9 1 9 4.0 CCOC(=O)CC(NC(=O)c1cc2c(=O)n3cccc(C)c3nc2s1)c1ccc(OCC)c(OC)c1 nan
CHEMBL1434864 35136 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 9 1 9 4.0 CCOC(=O)CC(NC(=O)c1cc2c(=O)n3cccc(C)c3nc2s1)c1ccc(OCC)c(OC)c1 nan
16015297 35241 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 5 5.3 CCn1c(CN2CCC(C)CC2)nc2cc(NC(=O)COc3ccc(Cl)c(C)c3)ccc21 nan
CHEMBL1436095 35241 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 5 5.3 CCn1c(CN2CCC(C)CC2)nc2cc(NC(=O)COc3ccc(Cl)c(C)c3)ccc21 nan
7526401 35254 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 4 2.2 N#Cc1ccccc1NS(=O)(=O)c1cc2c3c(c1)CCN3C(=O)CC2 nan
CHEMBL1436243 35254 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 4 2.2 N#Cc1ccccc1NS(=O)(=O)c1cc2c3c(c1)CCN3C(=O)CC2 nan
16019444 35256 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 6 2.9 Cc1nc2sc(C)c(C)n2c(=O)c1S(=O)(=O)NCCc1ccc(Cl)cc1 nan
CHEMBL1436274 35256 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 6 2.9 Cc1nc2sc(C)c(C)n2c(=O)c1S(=O)(=O)NCCc1ccc(Cl)cc1 nan
1743255 35258 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 3 1 5 3.4 N#CCNC(=O)c1nn2c(C(F)(F)F)cc(-c3ccccc3)nc2c1Br nan
CHEMBL1436298 35258 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 3 1 5 3.4 N#CCNC(=O)c1nn2c(C(F)(F)F)cc(-c3ccccc3)nc2c1Br nan
1004082 35305 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 2 5 4.8 COc1ccc(-c2ccc3c(N)c(C(=O)NCc4ccc(C)cc4)sc3n2)cc1 nan
CHEMBL1437042 35305 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 2 5 4.8 COc1ccc(-c2ccc3c(N)c(C(=O)NCc4ccc(C)cc4)sc3n2)cc1 nan
16030497 35335 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 4 5.8 CCc1cccc(C)c1NC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1437361 35335 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 4 5.8 CCc1cccc(C)c1NC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
5297283 35370 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 1 5 2.5 COc1ccc(C2CC(=O)Nc3c2c(=O)nc2c(C)cccn32)cc1 nan
CHEMBL1437774 35370 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 1 5 2.5 COc1ccc(C2CC(=O)Nc3c2c(=O)nc2c(C)cccn32)cc1 nan
2980985 35458 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 2 3 3.2 CC(C)(C)C(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
CHEMBL1438501 35458 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 2 3 3.2 CC(C)(C)C(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
16027383 35491 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 8 3.7 Cc1ccccc1OCC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 nan
CHEMBL1438820 35491 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 8 3.7 Cc1ccccc1OCC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 nan
16030423 35630 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 4 5.2 Cc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1 nan
CHEMBL1440057 35630 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 4 5.2 Cc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1 nan
24816825 35640 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 3 3.4 O=C(c1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)cc1)N1CCC1 nan
CHEMBL1440121 35640 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 3 3.4 O=C(c1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)cc1)N1CCC1 nan
22583638 35760 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 7 3.9 C=CCn1c(SCC(=O)N2CCN(c3ccccc3)CC2)nc2c3ccccc3nc-2c1O nan
CHEMBL1441228 35760 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 7 3.9 C=CCn1c(SCC(=O)N2CCN(c3ccccc3)CC2)nc2c3ccccc3nc-2c1O nan
4066521 35772 12 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 6 2.4 CC(=O)c1sc(NC(=O)C2COc3ccccc3O2)nc1C nan
CHEMBL1441350 35772 12 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 6 2.4 CC(=O)c1sc(NC(=O)C2COc3ccccc3O2)nc1C nan
2965654 35842 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 5 5.1 O=C(Nc1ccc([N+](=O)[O-])cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
CHEMBL1441978 35842 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 5 5.1 O=C(Nc1ccc([N+](=O)[O-])cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
16008702 35967 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 10 1 8 3.3 CCOC(=O)CC(NC(=O)CCc1c(C)nc2ncnn2c1C)c1ccc(OC(C)C)cc1 nan
CHEMBL1443046 35967 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 10 1 8 3.3 CCOC(=O)CC(NC(=O)CCc1c(C)nc2ncnn2c1C)c1ccc(OC(C)C)cc1 nan
2854033 36050 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 0 3 5.2 Fc1ccc(N2N=C(c3cccs3)CC2c2ccccc2)cc1 nan
CHEMBL1443903 36050 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 0 3 5.2 Fc1ccc(N2N=C(c3cccs3)CC2c2ccccc2)cc1 nan
5904887 36068 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.9 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
CHEMBL1444052 36068 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.9 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
16249191 36229 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 2 10 0.0 CC(C)[C@H](NS(=O)(=O)c1ccc(Cl)cc1)C(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
CHEMBL1445550 36229 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 2 10 0.0 CC(C)[C@H](NS(=O)(=O)c1ccc(Cl)cc1)C(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
6236858 36350 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4ccncc4)C3c3ccccc3F)ccc2O1 nan
CHEMBL1446709 36350 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4ccncc4)C3c3ccccc3F)ccc2O1 nan
2946413 36450 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 4 4.9 OC(COc1ccc2ccccc2c1Br)Cn1cnc(-c2ccccc2)c1 nan
CHEMBL1447526 36450 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 4 4.9 OC(COc1ccc2ccccc2c1Br)Cn1cnc(-c2ccccc2)c1 nan
5168521 36468 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 1 5 3.7 Cc1cc(C)c(NC(=O)Cn2cnc3c(oc4ccccc43)c2=O)c(C)c1 nan
CHEMBL1447670 36468 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 1 5 3.7 Cc1cc(C)c(NC(=O)Cn2cnc3c(oc4ccccc43)c2=O)c(C)c1 nan
975514 36618 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 1 2 3.7 COc1ccc2cc(Br)ccc2c1CC(=O)NC(C)C nan
CHEMBL1448872 36618 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 1 2 3.7 COc1ccc2cc(Br)ccc2c1CC(=O)NC(C)C nan
5003875 36947 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1cccnc1Cl)c1cc(-c2ccc(Cl)cc2)on1 nan
CHEMBL1451527 36947 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1cccnc1Cl)c1cc(-c2ccc(Cl)cc2)on1 nan
16009656 37010 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 6 4.8 Cc1cccc(C(=O)Nc2ccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)cc2)c1 nan
CHEMBL1451944 37010 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 6 4.8 Cc1cccc(C(=O)Nc2ccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)cc2)c1 nan
8087990 37026 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 0 8 1.3 Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)N1CCN(c2ccccn2)CC1 nan
CHEMBL1452085 37026 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 0 8 1.3 Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)N1CCN(c2ccccn2)CC1 nan
2172625 37035 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 1 2 6 2.6 Cc1cc(C2C(C#N)=C(N)SC(N)=C2C#N)c(C)s1 nan
CHEMBL1452137 37035 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 1 2 6 2.6 Cc1cc(C2C(C#N)=C(N)SC(N)=C2C#N)c(C)s1 nan
2874437 37094 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 0 10 -0.3 Cn1c(=O)c2c(ncn2CC(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)n(C)c1=O nan
CHEMBL1452667 37094 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 0 10 -0.3 Cn1c(=O)c2c(ncn2CC(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)n(C)c1=O nan
3242606 37193 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 9 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc4c(c3)OCO4)nnc12 nan
CHEMBL1453430 37193 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 9 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc4c(c3)OCO4)nnc12 nan
5924128 37240 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1453845 37240 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
16025308 37250 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 5 3.1 O=C(Cn1c2ncccc2c(=O)n1-c1ccccc1)Nc1ccc(F)c(F)c1 nan
CHEMBL1453921 37250 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 5 3.1 O=C(Cn1c2ncccc2c(=O)n1-c1ccccc1)Nc1ccc(F)c(F)c1 nan
16009318 37294 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 5 3.3 Cc1cc(C)cc(OCc2cc(=O)n3cc(C)sc3n2)c1 nan
CHEMBL1454181 37294 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 5 3.3 Cc1cc(C)cc(OCc2cc(=O)n3cc(C)sc3n2)c1 nan
16015117 37314 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 4.0 COc1ccccc1OCC(=O)Nc1nc(-c2ccc(Br)cc2)ns1 nan
CHEMBL1454422 37314 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 4.0 COc1ccccc1OCC(=O)Nc1nc(-c2ccc(Br)cc2)ns1 nan
20920416 37383 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 4.0 COc1ccc(-n2nc3c(N4CCC(C(=O)NCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1454925 37383 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 4.0 COc1ccc(-n2nc3c(N4CCC(C(=O)NCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
35802 37385 104 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 3 2 4 3.1 COC(=O)Nc1nc2cc(C(=O)c3ccc(F)cc3)ccc2[nH]1 nan
CHEMBL1454946 37385 104 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 3 2 4 3.1 COC(=O)Nc1nc2cc(C(=O)c3ccc(F)cc3)ccc2[nH]1 nan
5739327 37439 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Cl)c1)c1ccc2c(c1)OCO2 nan
CHEMBL1455509 37439 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Cl)c1)c1ccc2c(c1)OCO2 nan
20923165 37536 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 1 6 2.4 CCC(C)(C)NS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1456385 37536 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 1 6 2.4 CCC(C)(C)NS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
3356561 37614 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 6 3.9 CCC1(C)Cc2c(sc3nc(SC)nc(S)c23)CO1 nan
CHEMBL1457175 37614 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 6 3.9 CCC1(C)Cc2c(sc3nc(SC)nc(S)c23)CO1 nan
16018620 37625 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.2 O=C(CSc1nncn2c1cc1occc12)Nc1ccccc1C(F)(F)F nan
CHEMBL1457242 37625 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.2 O=C(CSc1nncn2c1cc1occc12)Nc1ccccc1C(F)(F)F nan
24686163 37716 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 3 5.1 CCN(CC)C(=O)c1ccc(NC(=O)c2sccc2-c2ccccc2)cc1 nan
CHEMBL1457962 37716 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 3 5.1 CCN(CC)C(=O)c1ccc(NC(=O)c2sccc2-c2ccccc2)cc1 nan
3927980 37753 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 6 3.1 CCCN1C(=O)C2(C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCCOC)c2ccccc21 nan
CHEMBL1458233 37753 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 6 3.1 CCCN1C(=O)C2(C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCCOC)c2ccccc21 nan
4962629 37787 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 1 4 3.5 Cc1cc(F)ccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
CHEMBL1458588 37787 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 1 4 3.5 Cc1cc(F)ccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
6460246 37788 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 2 0 5 3.1 Cc1nnc2c(SC(C)C)nc3ccccc3n12 nan
CHEMBL1458589 37788 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 2 0 5 3.1 Cc1nnc2c(SC(C)C)nc3ccccc3n12 nan
7475827 37867 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 0 9 0.2 CC(C)Cc1nc(SCC(=O)N2CCOCC2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1459222 37867 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 0 9 0.2 CC(C)Cc1nc(SCC(=O)N2CCOCC2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
3239559 37976 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 2 0 3 3.4 CCn1c(=S)ccc2ccc(OC)cc21 nan
CHEMBL1460186 37976 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 2 0 3 3.4 CCn1c(=S)ccc2ccc(OC)cc21 nan
4091063 38083 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 7 2.1 COC(=O)c1ccc(NC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)cc1 nan
CHEMBL1461057 38083 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 7 2.1 COC(=O)c1ccc(NC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)cc1 nan
135413805 38191 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 3 9 1.2 N#Cc1cc(Nc2c(N)ncnc2O)c([N+](=O)[O-])cc1C#N nan
CHEMBL1462053 38191 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 3 9 1.2 N#Cc1cc(Nc2c(N)ncnc2O)c([N+](=O)[O-])cc1C#N nan
4636986 38274 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 8 2 10 0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCCN4CCOCC4)c3nc12 nan
CHEMBL1462720 38274 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 8 2 10 0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCCN4CCOCC4)c3nc12 nan
993137 38311 17 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 3.4 CC(=O)c1sc(NC(=O)COc2ccc(Br)cc2)nc1C nan
CHEMBL1463012 38311 17 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 3.4 CC(=O)c1sc(NC(=O)COc2ccc(Br)cc2)nc1C nan
2225463 38366 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 1 3 3.3 O=C(NCCCN1CCCC1=O)c1sc2ccccc2c1Cl nan
CHEMBL1463545 38366 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 1 3 3.3 O=C(NCCCN1CCCC1=O)c1sc2ccccc2c1Cl nan
6184422 38437 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 10 1 8 3.5 CCCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1464067 38437 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 10 1 8 3.5 CCCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
135449395 38444 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 8 3.1 CCN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
CHEMBL1464106 38444 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 8 3.1 CCN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
5778449 38532 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 8 0.8 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCOC)CC1 nan
CHEMBL1464778 38532 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 8 0.8 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCOC)CC1 nan
2457314 38543 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 10 0.1 COc1ccc(OC)c(/C=C/C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
CHEMBL1464838 38543 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 10 0.1 COc1ccc(OC)c(/C=C/C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
3791918 38554 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)ccc2Cl)n1 nan
CHEMBL1464872 38554 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)ccc2Cl)n1 nan
985269 38599 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 0 5 4.7 c1ccc(-c2cc3c(N4CCN(c5ccccc5)CC4)ncnc3s2)cc1 nan
CHEMBL1465210 38599 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 0 5 4.7 c1ccc(-c2cc3c(N4CCN(c5ccccc5)CC4)ncnc3s2)cc1 nan
1435001 38675 5 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 2 6 2.8 CCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
CHEMBL1465814 38675 5 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 2 6 2.8 CCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
1479844 38713 16 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 0 4 5.2 CSc1nc(Sc2ccccc2Cl)c2ccccc2n1 nan
CHEMBL1466134 38713 16 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 0 4 5.2 CSc1nc(Sc2ccccc2Cl)c2ccccc2n1 nan
1836205 38716 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 8 0.8 COCCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1466152 38716 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 8 0.8 COCCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
2982726 38751 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 2 7 1.1 CCOC(=O)C1=C(CN2CCOCC2)NC(=O)NC1c1cccc([N+](=O)[O-])c1 nan
CHEMBL1466461 38751 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 2 7 1.1 CCOC(=O)C1=C(CN2CCOCC2)NC(=O)NC1c1cccc([N+](=O)[O-])c1 nan
5831389 38816 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 6 3.9 Cc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1466919 38816 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 6 3.9 Cc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
2161641 38872 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 2 7 3.0 CCOc1ncccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 nan
CHEMBL1467371 38872 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 2 7 3.0 CCOc1ncccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 nan
2146410 38874 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 2 3.3 CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
CHEMBL1467397 38874 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 2 3.3 CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
5028075 38910 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 6 3.9 COc1ccc(NC(=O)COC(=O)c2cc(SC)ccc2Cl)c(OC)c1 nan
CHEMBL1467702 38910 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 6 3.9 COc1ccc(NC(=O)COC(=O)c2cc(SC)ccc2Cl)c(OC)c1 nan
5786830 38921 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 3.4 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)cc1 nan
CHEMBL1467854 38921 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 3.4 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)cc1 nan
652110 39009 5 None -2 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 4 0 5 3.0 COC(=O)CSc1nc(C(C)C)nc2ccccc12 nan
CHEMBL1468599 39009 5 None -2 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 4 0 5 3.0 COC(=O)CSc1nc(C(C)C)nc2ccccc12 nan
20904121 39084 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 8 1.7 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(N4CCOCC4)nn23)c1 nan
CHEMBL1469174 39084 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 8 1.7 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(N4CCOCC4)nn23)c1 nan
5726945 39098 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 0 4 3.5 CC(=O)c1ccc(/C=C/c2nc3ccccc3n2C)o1 nan
CHEMBL1469326 39098 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 0 4 3.5 CC(=O)c1ccc(/C=C/c2nc3ccccc3n2C)o1 nan
3812545 39204 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 3.7 COc1ccc(OC)c(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1470290 39204 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 3.7 COc1ccc(OC)c(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
2964736 39220 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(c4cc(C)on4)C3c3cccs3)oc12 nan
CHEMBL1470378 39220 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(c4cc(C)on4)C3c3cccs3)oc12 nan
15988466 39477 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.3 COc1ccc(NC(=O)Cn2c(=O)c3cc(Cl)ccc3n3nncc23)cc1 nan
CHEMBL1472605 39477 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.3 COc1ccc(NC(=O)Cn2c(=O)c3cc(Cl)ccc3n3nncc23)cc1 nan
16011470 39493 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 10 1 6 5.8 COc1ccc(CCNC(=O)c2ccc(Cn3c(SCc4ccccc4)nc4cccnc43)cc2)cc1 nan
CHEMBL1472792 39493 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 10 1 6 5.8 COc1ccc(CCNC(=O)c2ccc(Cn3c(SCc4ccccc4)nc4cccnc43)cc2)cc1 nan
6229347 39574 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 2 5 3.0 COc1ccccc1CCNC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
CHEMBL1473886 39574 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 2 5 3.0 COc1ccccc1CCNC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
20886471 39586 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 7 1 4 4.3 CCCOc1ccc(CNC(=O)c2ccc3c(c2)N(CC)CCS3)cc1 nan
CHEMBL1474147 39586 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 7 1 4 4.3 CCCOc1ccc(CNC(=O)c2ccc3c(c2)N(CC)CCS3)cc1 nan
15988056 39647 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 2 4 3.5 CCCCCn1c(=O)[nH]c2cc(C(=O)NCc3ccc(Cl)cc3)ccc2c1=O nan
CHEMBL1475000 39647 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 2 4 3.5 CCCCCn1c(=O)[nH]c2cc(C(=O)NCc3ccc(Cl)cc3)ccc2c1=O nan
5297460 39658 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 5 1 5 4.0 CCOc1ccc(-c2oc3ccccc3c(=O)c2O)cc1OCC nan
CHEMBL1475143 39658 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 5 1 5 4.0 CCOc1ccc(-c2oc3ccccc3c(=O)c2O)cc1OCC nan
16018222 39667 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 3.0 COc1cccc(NC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1475268 39667 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 3.0 COc1cccc(NC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
135410479 39677 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 2 4 5.5 Cc1ccc(NC(=O)c2cnn3c2NC(c2ccccc2)=CC3c2ccccc2)cc1 nan
CHEMBL1475406 39677 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 2 4 5.5 Cc1ccc(NC(=O)c2cnn3c2NC(c2ccccc2)=CC3c2ccccc2)cc1 nan
16031507 39678 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 6 4.1 COc1ccc(-c2nnc(SCC(=O)Nc3cccc(F)c3)s2)cc1 nan
CHEMBL1475415 39678 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 6 4.1 COc1ccc(-c2nnc(SCC(=O)Nc3cccc(F)c3)s2)cc1 nan
16015334 39741 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 6 5.7 COc1ccc(Cc2c(C)nn(-c3nc(C)c(C(=O)Nc4ccc(C)cc4C)s3)c2C)cc1 nan
CHEMBL1476342 39741 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 6 5.7 COc1ccc(Cc2c(C)nn(-c3nc(C)c(C(=O)Nc4ccc(C)cc4C)s3)c2C)cc1 nan
2033254 39788 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 7 2.8 CSc1nc(NCCCN(C)C)c2c3c(sc2n1)CN(C)CC3 nan
CHEMBL1476899 39788 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 7 2.8 CSc1nc(NCCCN(C)C)c2c3c(sc2n1)CN(C)CC3 nan
1138445 39887 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1477799 39887 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
1442565 39930 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 5 3.9 CCOC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
CHEMBL1478306 39930 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 5 3.9 CCOC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
1005239 40024 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 2 1 5 5.8 N#Cc1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N nan
CHEMBL1479144 40024 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 2 1 5 5.8 N#Cc1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N nan
16018188 40052 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 9 1 5 3.8 CCOc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccccc32)cc1 nan
CHEMBL1479369 40052 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 9 1 5 3.8 CCOc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccccc32)cc1 nan
5914213 40543 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 7 3.3 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1483546 40543 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 7 3.3 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
796660 40627 4 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 0 5 2.9 COc1cc2oc(=O)c(Br)c(C)c2c(OC)c1OC nan
CHEMBL1484186 40627 4 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 0 5 2.9 COc1cc2oc(=O)c(Br)c(C)c2c(OC)c1OC nan
16025365 40701 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 7 1 7 5.4 CC(=O)c1cccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2)S3(=O)=O)c1 nan
CHEMBL1484843 40701 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 7 1 7 5.4 CC(=O)c1cccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2)S3(=O)=O)c1 nan
2881633 40727 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 2 5 2.3 Cc1nnc(Nc2ccc(S(N)(=O)=O)cc2)c2ccccc12 nan
CHEMBL1485038 40727 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 2 5 2.3 Cc1nnc(Nc2ccc(S(N)(=O)=O)cc2)c2ccccc12 nan
16020293 40759 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 562 8 2 7 4.3 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3ccc(C)cc3)c2=O)cc1 nan
CHEMBL1485379 40759 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 562 8 2 7 4.3 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3ccc(C)cc3)c2=O)cc1 nan
866572 40807 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 1 0 6 1.3 CN1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1485808 40807 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 1 0 6 1.3 CN1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
15991110 40826 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 3 5.2 Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1c(F)cccc1F nan
CHEMBL1485996 40826 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 3 5.2 Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1c(F)cccc1F nan
20869704 40830 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 1 10 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2cccc(OC)c2)c1=O nan
CHEMBL1486007 40830 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 1 10 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2cccc(OC)c2)c1=O nan
2951279 40831 13 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 7 4.2 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(Cc4ccco4)C3c3cccnc3)oc12 nan
CHEMBL1486010 40831 13 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 7 4.2 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(Cc4ccco4)C3c3cccnc3)oc12 nan
3647805 40918 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 8 2 4 3.1 CCCCC(CC)CNC(=O)CC1N=C2c3ccccc3NC(=S)N2C1=O nan
CHEMBL1486794 40918 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 8 2 4 3.1 CCCCC(CC)CNC(=O)CC1N=C2c3ccccc3NC(=S)N2C1=O nan
3149629 40969 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 1 5 2.4 O=C(O)CSc1ncnc2sc3c(c12)CCC3 nan
CHEMBL1487236 40969 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 1 5 2.4 O=C(O)CSc1ncnc2sc3c(c12)CCC3 nan
6296199 40980 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 9 1 8 2.9 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1487315 40980 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 9 1 8 2.9 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3494131 41173 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 7 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccs2)no1 nan
CHEMBL1488696 41173 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 7 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccs2)no1 nan
16016559 41227 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 3 1 4 3.7 Cc1ccc(-c2nonc2NC(=O)c2ccc(F)cc2)cc1C nan
CHEMBL1489095 41227 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 3 1 4 3.7 Cc1ccc(-c2nonc2NC(=O)c2ccc(F)cc2)cc1C nan
4604410 41393 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 4 3.1 Cc1c(Cl)cccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
CHEMBL1490398 41393 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 4 3.1 Cc1c(Cl)cccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
15992220 41402 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 1 2 4 0.9 CC(=O)N=C(N)Nc1nc(=O)c2ccccc2s1 nan
3862718 41402 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 1 2 4 0.9 CC(=O)N=C(N)Nc1nc(=O)c2ccccc2s1 nan
5941821 41402 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 1 2 4 0.9 CC(=O)N=C(N)Nc1nc(=O)c2ccccc2s1 nan
CHEMBL1490493 41402 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 1 2 4 0.9 CC(=O)N=C(N)Nc1nc(=O)c2ccccc2s1 nan
5307465 41535 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 0 6 2.5 Cc1sc2nc3ccc(N4CCCC4)nn3c(=O)c2c1C nan
CHEMBL1491386 41535 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 0 6 2.5 Cc1sc2nc3ccc(N4CCCC4)nn3c(=O)c2c1C nan
648659 41602 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 8 1.5 CCCn1c(SCC(=O)N2CCc3ccccc3C2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1491811 41602 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 8 1.5 CCCn1c(SCC(=O)N2CCc3ccccc3C2)nc2c1c(=O)n(C)c(=O)n2C nan
3240716 41617 10 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 11 2 7 3.9 CCOc1cc2[nH]c(=S)n(CCCCC(=O)NCc3ccco3)c(=O)c2cc1OCC nan
CHEMBL1491907 41617 10 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 11 2 7 3.9 CCOc1cc2[nH]c(=S)n(CCCCC(=O)NCc3ccco3)c(=O)c2cc1OCC nan
20917809 41642 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 2.1 O=C1c2cccnc2C(=O)N1Cc1ccc(F)cc1S(=O)(=O)NCc1ccco1 nan
CHEMBL1492082 41642 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 2.1 O=C1c2cccnc2C(=O)N1Cc1ccc(F)cc1S(=O)(=O)NCc1ccco1 nan
6533452 41655 17 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 4 4.4 COc1ccc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc1OC nan
CHEMBL1492209 41655 17 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 4 4.4 COc1ccc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc1OC nan
135414697 41668 14 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 3.7 N#Cc1c(O)nc(SCc2ccc(F)cc2)nc1-c1ccco1 nan
CHEMBL1492324 41668 14 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 3.7 N#Cc1c(O)nc(SCc2ccc(F)cc2)nc1-c1ccco1 nan
3151464 41706 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 7 2.1 COCCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL1492596 41706 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 7 2.1 COCCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 nan
3241814 41712 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 3 1 6 1.1 Cn1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1492641 41712 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 3 1 6 1.1 Cn1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc21 nan
4118355 41800 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 4 4.7 Cc1ccc(C(C)(C)C)cc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
CHEMBL1493417 41800 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 4 4.7 Cc1ccc(C(C)(C)C)cc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
7899292 41807 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 8 1.5 COc1cccc(C(=O)NCC(=O)OCc2cc(=O)n3c(C)csc3n2)c1 nan
CHEMBL1493482 41807 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 8 1.5 COc1cccc(C(=O)NCC(=O)OCc2cc(=O)n3c(C)csc3n2)c1 nan
16014523 41868 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 5 4.8 Cc1cc(Nc2ccc(C)c(Cl)c2)n2nc(-c3ccccc3)nc2n1 nan
CHEMBL1494140 41868 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 5 4.8 Cc1cc(Nc2ccc(C)c(Cl)c2)n2nc(-c3ccccc3)nc2n1 nan
4578483 41896 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 6 6.0 COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)Nc4cccc(Cl)c4Cl)cc3n2)cc1OC nan
CHEMBL1494437 41896 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 6 6.0 COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)Nc4cccc(Cl)c4Cl)cc3n2)cc1OC nan
2740372 41911 11 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 5 3.8 CCOC(=O)c1csc(-c2sccc2Br)n1 nan
CHEMBL1494595 41911 11 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 5 3.8 CCOC(=O)c1csc(-c2sccc2Br)n1 nan
6245779 41936 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 6 5.1 Cc1cc(OCc2ccccc2)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
CHEMBL1494772 41936 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 6 5.1 Cc1cc(OCc2ccccc2)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
2961508 41986 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccncc1 nan
5740308 41986 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccncc1 nan
9587859 41986 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccncc1 nan
CHEMBL1495283 41986 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccncc1 nan
7743649 42091 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 4 4.3 Cc1cc(SCC(=O)NC2(C#N)CCCCC2)nc2c(C)cccc12 nan
CHEMBL1496365 42091 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 4 4.3 Cc1cc(SCC(=O)NC2(C#N)CCCCC2)nc2c(C)cccc12 nan
7709279 42148 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 7 3.1 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCS3 nan
CHEMBL1496847 42148 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 7 3.1 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCS3 nan
5760983 42149 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 4 1 4 5.4 O=C(C1=C(O)C(=O)N(c2ccccn2)C1c1ccc(Br)cc1)c1ccc(Br)cc1 nan
CHEMBL1496850 42149 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 4 1 4 5.4 O=C(C1=C(O)C(=O)N(c2ccccn2)C1c1ccc(Br)cc1)c1ccc(Br)cc1 nan
16195573 42182 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 9 2 7 3.2 CCOc1cc2[nH]c(=S)n(CCC(=O)NCc3ccco3)c(=O)c2cc1OCC nan
CHEMBL1497122 42182 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 9 2 7 3.2 CCOc1cc2[nH]c(=S)n(CCC(=O)NCc3ccco3)c(=O)c2cc1OCC nan
265605 42347 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 236 1 0 6 0.1 CC(C)c1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1498670 42347 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 236 1 0 6 0.1 CC(C)c1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
20875207 42526 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 2 3 4.2 O=C(Nc1ccccc1F)c1oc2ccccc2c1NC(=O)C1CC1 nan
CHEMBL1500175 42526 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 2 3 4.2 O=C(Nc1ccccc1F)c1oc2ccccc2c1NC(=O)C1CC1 nan
17583267 42597 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 3.8 COc1cc(NC(=O)COc2cc(C)cc3oc(=O)c(C)c(C)c23)cc(OC)c1OC nan
CHEMBL1500728 42597 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 3.8 COc1cc(NC(=O)COc2cc(C)cc3oc(=O)c(C)c(C)c23)cc(OC)c1OC nan
2768366 42795 59 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 3 2 4 2.2 COc1ccc(-c2ccc(C(=O)O)c(O)n2)cc1 nan
CHEMBL1502516 42795 59 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 3 2 4 2.2 COc1ccc(-c2ccc(C(=O)O)c(O)n2)cc1 nan
859554 42847 17 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 7 3.3 Cc1cc(NC(=O)CSc2ncnc3sc(C)c(C)c23)no1 nan
CHEMBL1503032 42847 17 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 7 3.3 Cc1cc(NC(=O)CSc2ncnc3sc(C)c(C)c23)no1 nan
5294012 42927 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 2 7 4.0 CC(C)n1c2ccccc2c2nnc(SCC(=O)Nc3ccccc3C(=O)O)nc21 nan
CHEMBL1503589 42927 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 2 7 4.0 CC(C)n1c2ccccc2c2nnc(SCC(=O)Nc3ccccc3C(=O)O)nc21 nan
20956972 43108 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 1.9 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)cc1F nan
CHEMBL1505377 43108 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 1.9 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)cc1F nan
4157311 43118 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 511 5 0 9 4.0 O=c1c2sccc2nc(SCc2cc(=O)n3cc(Br)ccc3n2)n1Cc1ccccn1 nan
CHEMBL1505478 43118 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 511 5 0 9 4.0 O=c1c2sccc2nc(SCc2cc(=O)n3cc(Br)ccc3n2)n1Cc1ccccn1 nan
5936247 43119 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1ccccc1C1C(C(=O)c2ccc3c(c2)OCCO3)=C(O)C(=O)N1Cc1cccnc1 nan
CHEMBL1505481 43119 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1ccccc1C1C(C(=O)c2ccc3c(c2)OCCO3)=C(O)C(=O)N1Cc1cccnc1 nan
3152549 43348 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1Cl)c1ccco1 nan
CHEMBL1507420 43348 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1Cl)c1ccco1 nan
2905772 43365 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 11 -0.4 CCOC(=O)Cc1csc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)n1 nan
CHEMBL1507551 43365 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 11 -0.4 CCOC(=O)Cc1csc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)n1 nan
20888750 43377 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 8 1.8 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(C)CC2)s1 nan
CHEMBL1507635 43377 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 8 1.8 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(C)CC2)s1 nan
664007 43475 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 5 5.5 Cc1cc(NC(=O)c2ccc3nc(-c4ccccc4)c(-c4ccccc4)nc3c2)no1 nan
CHEMBL1508441 43475 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 5 5.5 Cc1cc(NC(=O)c2ccc3nc(-c4ccccc4)c(-c4ccccc4)nc3c2)no1 nan
1862355 43504 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 1 5 3.3 COc1ccc(-c2cc(-c3cccnc3)c(C#N)c(N)n2)cc1 nan
CHEMBL1508668 43504 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 1 5 3.3 COc1ccc(-c2cc(-c3cccnc3)c(C#N)c(N)n2)cc1 nan
6224737 43574 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 1 8 4.0 COc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1509331 43574 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 1 8 4.0 COc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
22514400 43652 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 0 7 0.6 CCOC(=O)C1CCN(C(=O)Cn2nc(C)n3cccc3c2=O)CC1 nan
CHEMBL1510088 43652 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 0 7 0.6 CCOC(=O)C1CCN(C(=O)Cn2nc(C)n3cccc3c2=O)CC1 nan
4547589 43676 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 3 4.9 CC(C)(C)C(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccccc1Cl nan
CHEMBL1510328 43676 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 3 4.9 CC(C)(C)C(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccccc1Cl nan
24792485 43697 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1cc2cc(C#N)c(SCC(=O)Nc3cc(C)on3)nc2cc1OC nan
CHEMBL1510493 43697 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1cc2cc(C#N)c(SCC(=O)Nc3cc(C)on3)nc2cc1OC nan
6042599 43821 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 6 3.5 Cc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)cc1 nan
CHEMBL1511435 43821 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 6 3.5 Cc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)cc1 nan
16027534 43872 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)cc1 nan
CHEMBL1512013 43872 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)cc1 nan
16024951 43891 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 6 2 6 4.8 CCOc1ccc(Nc2nc(N)c(C(=O)c3ccccc3Cl)s2)cc1 nan
CHEMBL1512414 43891 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 6 2 6 4.8 CCOc1ccc(Nc2nc(N)c(C(=O)c3ccccc3Cl)s2)cc1 nan
4395410 44003 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 0 4 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCc1ccc(F)cc1 nan
CHEMBL1514024 44003 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 0 4 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCc1ccc(F)cc1 nan
16018164 44032 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 5 3.4 COc1ccccc1CNC(=O)CCCn1c(=O)c2cccn2c2ccccc21 nan
CHEMBL1514529 44032 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 5 3.4 COc1ccccc1CNC(=O)CCCn1c(=O)c2cccn2c2ccccc21 nan
4081154 44113 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 3 5.1 O=C(Nc1c(C(=O)c2ccccc2)oc2ccccc12)c1ccc(F)cc1 nan
CHEMBL1515694 44113 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 3 5.1 O=C(Nc1c(C(=O)c2ccccc2)oc2ccccc12)c1ccc(F)cc1 nan
135546812 44130 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 2 5 3.6 CCc1ccc(NC(=O)CSc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)cc1 nan
CHEMBL1515954 44130 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 2 5 3.6 CCc1ccc(NC(=O)CSc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)cc1 nan
16022285 44189 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 2 6 2.3 Cc1nc2cccnc2n1-c1cccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c1 nan
CHEMBL1516713 44189 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 2 6 2.3 Cc1nc2cccnc2n1-c1cccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c1 nan
1466061 44200 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 5 3.8 CCOc1ccc2nc(O)c(CN(CCc3ccccc3)C(=O)N3CCOCC3)cc2c1 nan
CHEMBL1516817 44200 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 5 3.8 CCOc1ccc2nc(O)c(CN(CCc3ccccc3)C(=O)N3CCOCC3)cc2c1 nan
3433386 44288 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 2 6 2.0 NS(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
CHEMBL1517698 44288 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 2 6 2.0 NS(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
16018535 44429 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 1 4 4.2 CC(=O)N1CCOc2cc(S(=O)(=O)Nc3cc(C(F)(F)F)ccc3Cl)c(C)cc21 nan
CHEMBL1518991 44429 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 1 4 4.2 CC(=O)N1CCOc2cc(S(=O)(=O)Nc3cc(C(F)(F)F)ccc3Cl)c(C)cc21 nan
2135572 44444 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 8 4.0 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCO4)cc1 nan
CHEMBL1519131 44444 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 8 4.0 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCO4)cc1 nan
16025796 44499 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.4 CC(NC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1)c1ccccc1 nan
CHEMBL1519614 44499 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.4 CC(NC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1)c1ccccc1 nan
16030429 44642 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(F)cc2)cc1 nan
CHEMBL1520828 44642 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(F)cc2)cc1 nan
15988916 44653 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 8 2 8 4.4 Cc1cc(C)c(NC(=O)Cn2c(=O)n(Cc3ccc(C(=O)NCc4ccco4)cc3)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1520905 44653 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 8 2 8 4.4 Cc1cc(C)c(NC(=O)Cn2c(=O)n(Cc3ccc(C(=O)NCc4ccco4)cc3)c(=O)c3sccc32)c(C)c1 nan
289464 44701 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 1 1 4.5 O=C(O)c1cc2ccccc2c2cc(Br)ccc12 nan
CHEMBL1521339 44701 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 1 1 4.5 O=C(O)c1cc2ccccc2c2cc(Br)ccc12 nan
2745168 44761 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 3 1 6 1.2 COCc1nc(S)c(C#N)cc1C(=O)OC nan
CHEMBL1521853 44761 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 3 1 6 1.2 COCc1nc(S)c(C#N)cc1C(=O)OC nan
689389 44807 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 6 1 5 3.4 CCN(CC)CCNc1cc(C)c(C#N)c2nc3ccccc3n12 nan
CHEMBL1522224 44807 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 6 1 5 3.4 CCN(CC)CCNc1cc(C)c(C#N)c2nc3ccccc3n12 nan
1167955 44941 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 2 5 5.0 O=C(CSc1nc(-c2ccc(F)cc2)nc2ccc(F)cc12)Nc1cccc(C(=O)O)c1 nan
CHEMBL1523483 44941 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 2 5 5.0 O=C(CSc1nc(-c2ccc(F)cc2)nc2ccc(F)cc12)Nc1cccc(C(=O)O)c1 nan
17201681 45003 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 2 2.4 O=C(C1CC(=O)N(c2ccc(Br)cc2)C1)N1CCCC1 nan
CHEMBL1524084 45003 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 2 2.4 O=C(C1CC(=O)N(c2ccc(Br)cc2)C1)N1CCCC1 nan
16018239 45047 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 3 3.5 CCOc1ccc(NC(=O)N2CCOc3ccccc32)cc1 nan
CHEMBL1524566 45047 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 3 3.5 CCOc1ccc(NC(=O)N2CCOc3ccccc32)cc1 nan
818605 45072 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 0 4 2.3 COc1ccc(C=O)cc1CN1C(=O)c2ccccc2C1=O nan
CHEMBL1524802 45072 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 0 4 2.3 COc1ccc(C=O)cc1CN1C(=O)c2ccccc2C1=O nan
16015121 45092 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 4.0 COc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1 nan
CHEMBL1525000 45092 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 4.0 COc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1 nan
4624396 45118 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.1 CCOc1ccc(-c2csc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)n2)cc1 nan
CHEMBL1525327 45118 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.1 CCOc1ccc(-c2csc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)n2)cc1 nan
551547 45135 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 3 4.6 O=C(NCC1CCCO1)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1525441 45135 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 3 4.6 O=C(NCC1CCCO1)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
2904040 45162 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 2 3 3.0 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(-c3ccccc3)cc2)cc1 nan
CHEMBL1525655 45162 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 2 3 3.0 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(-c3ccccc3)cc2)cc1 nan
2868184 45183 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 3 4.6 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1ccc(Cl)cc1 nan
CHEMBL1525829 45183 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 3 4.6 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1ccc(Cl)cc1 nan
16018537 45220 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 1.6 CCOC(=O)C1CCCN(C(=O)CCS(=O)(=O)c2cc3c(cc2Cl)NC(=O)CO3)C1 nan
CHEMBL1526153 45220 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 1.6 CCOC(=O)C1CCCN(C(=O)CCS(=O)(=O)c2cc3c(cc2Cl)NC(=O)CO3)C1 nan
3151412 45354 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 8 0.7 COCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1527265 45354 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 8 0.7 COCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc21 nan
3772745 45398 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 4 4.9 COc1cccc(-c2cc(C(=O)NCC3CCCO3)c3cc(Br)cc(C)c3n2)c1 nan
CHEMBL1527660 45398 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 4 4.9 COc1cccc(-c2cc(C(=O)NCC3CCCO3)c3cc(Br)cc(C)c3n2)c1 nan
1253448 45412 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 0 7 2.3 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1527795 45412 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 0 7 2.3 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
661360 45419 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 7 1.5 COc1ccc(-n2ncc3c(N4CCC(C(N)=O)CC4)ncnc32)cc1 nan
CHEMBL1527862 45419 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 7 1.5 COc1ccc(-n2ncc3c(N4CCC(C(N)=O)CC4)ncnc32)cc1 nan
1077518 45510 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 2 6 2.5 CCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL1528629 45510 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 2 6 2.5 CCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 nan
16813521 45554 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 1 8 1.8 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCCC4)nn23)cc1 nan
CHEMBL1529059 45554 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 1 8 1.8 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCCC4)nn23)cc1 nan
54694033 45579 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 5 2 5 2.6 CCCn1c(=O)c(C(=O)NCc2ccco2)c(O)c2ccccc21 nan
CHEMBL1529241 45579 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 5 2 5 2.6 CCCn1c(=O)c(C(=O)NCc2ccco2)c(O)c2ccccc21 nan
625773 45746 57 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 3 4.3 O=C(O)c1cc(-c2ccc(Cl)s2)nc2ccccc12 nan
CHEMBL153072 45746 57 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 3 4.3 O=C(O)c1cc(-c2ccc(Cl)s2)nc2ccccc12 nan
3151486 45764 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 2 8 1.8 CCOCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL1530888 45764 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 2 8 1.8 CCOCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cccc(C)c3nc21 nan
4216259 45804 6 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 8 2.0 CCCCn1c(=O)[nH]c(=O)c2c1nc(Cn1ncc(Cl)c(Cl)c1=O)n2CCC nan
CHEMBL1531245 45804 6 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 8 2.0 CCCCn1c(=O)[nH]c(=O)c2c1nc(Cn1ncc(Cl)c(Cl)c1=O)n2CCC nan
2737056 45891 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 191 1 0 4 1.4 O=C1CC(=O)c2c1cccc2[N+](=O)[O-] nan
CHEMBL1532031 45891 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 191 1 0 4 1.4 O=C1CC(=O)c2c1cccc2[N+](=O)[O-] nan
2085635 45942 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 2 0 5 2.9 Cc1ccc2nc(Cn3cc(C(F)(F)F)cc(Cl)c3=O)cc(=O)n2c1 nan
CHEMBL1532467 45942 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 2 0 5 2.9 Cc1ccc2nc(Cn3cc(C(F)(F)F)cc(Cl)c3=O)cc(=O)n2c1 nan
3721626 45973 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 5 3.9 COc1ccc2c(c1)c1ncnc(N(C)C3CCCCC3)c1n2C nan
CHEMBL1532723 45973 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 5 3.9 COc1ccc2c(c1)c1ncnc(N(C)C3CCCCC3)c1n2C nan
3312243 46216 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(Cc4ccc(F)cc4)c3nc12 nan
CHEMBL1535016 46216 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(Cc4ccc(F)cc4)c3nc12 nan
135403580 46317 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 2 7 4.6 N#Cc1c(O)nc(SCC(=O)Nc2ccc(OC(F)(F)Cl)cc2)nc1-c1ccccc1 nan
CHEMBL1536174 46317 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 2 7 4.6 N#Cc1c(O)nc(SCC(=O)Nc2ccc(OC(F)(F)Cl)cc2)nc1-c1ccccc1 nan
5310128 46333 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1ccc2nnc(-c3ccncc3)n2n1)NCC1CCCO1 nan
CHEMBL1536319 46333 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1ccc2nnc(-c3ccncc3)n2n1)NCC1CCCO1 nan
20878456 46366 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 3 0 8 2.3 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2ccccc23)cc1 nan
CHEMBL1536657 46366 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 3 0 8 2.3 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2ccccc23)cc1 nan
5059230 46377 3 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 2.5 N#CC1=C([C-](C#N)C#N)NC(O)(C2CC2)C([n+]2ccccc2)C1c1ccccc1F nan
CHEMBL1536738 46377 3 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 2.5 N#CC1=C([C-](C#N)C#N)NC(O)(C2CC2)C([n+]2ccccc2)C1c1ccccc1F nan
5235682 46446 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(Cl)c2)no1 nan
CHEMBL1537295 46446 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(Cl)c2)no1 nan
7190492 46617 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
CHEMBL1538682 46617 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
3220383 46691 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 6 3.3 CC(C)CC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
CHEMBL1539378 46691 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 6 3.3 CC(C)CC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
6133031 46719 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 7 2.4 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1539594 46719 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 7 2.4 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
1567287 46824 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 6 -1.0 CN1C(=O)C(=CNCCN2CCOCC2)C(=O)N(C)C1=S nan
CHEMBL1540479 46824 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 6 -1.0 CN1C(=O)C(=CNCCN2CCOCC2)C(=O)N(C)C1=S nan
2983027 46841 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 1.8 O=C(NCc1cccnc1)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
CHEMBL1540590 46841 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 1.8 O=C(NCc1cccnc1)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
2431987 46866 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 4 1 5 3.0 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1540855 46866 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 4 1 5 3.0 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
3833515 46891 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 1 7 5.1 C=CCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1541029 46891 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 1 7 5.1 C=CCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
6273159 46978 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 4.6 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)c1 nan
CHEMBL1541682 46978 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 4.6 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)c1 nan
659524 47165 7 None -3 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 1 0 3 4.1 Brc1cc(Br)c2ncnc(N3CCCCC3)c2c1 nan
CHEMBL1543331 47165 7 None -3 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 1 0 3 4.1 Brc1cc(Br)c2ncnc(N3CCCCC3)c2c1 nan
16194876 47411 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(OC)c(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1545182 47411 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(OC)c(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
2997987 47442 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 2.0 Cc1sc2ncnc(OCC(=O)NCC3CCCO3)c2c1C nan
CHEMBL1545423 47442 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 2.0 Cc1sc2ncnc(OCC(=O)NCC3CCCO3)c2c1C nan
16188698 47532 0 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 2 4.2 Cc1ccccc1CC1(CO)CCCN(C(=O)c2cc(Cl)ccc2F)C1 nan
CHEMBL1546168 47532 0 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 2 4.2 Cc1ccccc1CC1(CO)CCCN(C(=O)c2cc(Cl)ccc2F)C1 nan
5389436 47653 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 8 3.8 COc1cccc(C2C(C(=O)c3ccc(OC)c(OC)c3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1547272 47653 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 8 3.8 COc1cccc(C2C(C(=O)c3ccc(OC)c(OC)c3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
16437942 47981 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 9 2.2 CCCS(=O)(=O)c1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)n1 nan
CHEMBL1550174 47981 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 9 2.2 CCCS(=O)(=O)c1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)n1 nan
3579665 48026 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 1 7 2.3 COC(=O)c1c(NC(=O)c2cccc(N3C(=O)CCC3=O)c2)sc2c1CCN(C(C)=O)C2 nan
CHEMBL1550602 48026 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 1 7 2.3 COC(=O)c1c(NC(=O)c2cccc(N3C(=O)CCC3=O)c2)sc2c1CCN(C(C)=O)C2 nan
5308895 48081 1 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 0 5 4.0 N#CC1=C2SCN(Cc3ccccc3)CN2C(=O)CC1c1cccs1 nan
CHEMBL1551015 48081 1 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 0 5 4.0 N#CC1=C2SCN(Cc3ccccc3)CN2C(=O)CC1c1cccs1 nan
16031535 48121 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 1 6 4.6 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(C)c(C)c3)s2)cc1 nan
CHEMBL1551622 48121 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 1 6 4.6 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(C)c(C)c3)s2)cc1 nan
16015115 48130 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 4.3 Cc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1 nan
CHEMBL1551830 48130 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 4.3 Cc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1 nan
15989679 48186 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 9 1 9 3.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc1OC nan
CHEMBL1552471 48186 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 9 1 9 3.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc1OC nan
16030838 48205 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 2 8 2.3 COc1ccc(-c2cc3ccc(O)c(CN4CCN(CCO)CC4)c3oc2=O)cc1OC nan
53229832 48205 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 2 8 2.3 COc1ccc(-c2cc3ccc(O)c(CN4CCN(CCO)CC4)c3oc2=O)cc1OC nan
CHEMBL1552774 48205 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 2 8 2.3 COc1ccc(-c2cc3ccc(O)c(CN4CCN(CCO)CC4)c3oc2=O)cc1OC nan
1004132 48239 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 2 4 4.9 Cc1ccc(CNC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1 nan
CHEMBL1553209 48239 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 2 4 4.9 Cc1ccc(CNC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1 nan
15988065 48242 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 2 1 8 3.6 O=c1c2cc3c(cc2nc2sc(Nc4ccc(F)c(Cl)c4)nn12)OCO3 nan
CHEMBL1553232 48242 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 2 1 8 3.6 O=c1c2cc3c(cc2nc2sc(Nc4ccc(F)c(Cl)c4)nn12)OCO3 nan
16008431 48249 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 5 4.1 O=C(c1ccc(F)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCO3 nan
CHEMBL1553329 48249 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 5 4.1 O=C(c1ccc(F)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCO3 nan
16018243 48252 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 1 1 2 4.1 Cc1c(Cl)cccc1NC(=O)N1CCOc2ccccc21 nan
CHEMBL1553372 48252 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 1 1 2 4.1 Cc1c(Cl)cccc1NC(=O)N1CCOc2ccccc21 nan
1364295 48282 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 2 5 5.3 O=C(COc1ccc(Cl)cc1)Nc1ccc(O)c(-c2nc3ccccc3s2)c1 nan
CHEMBL1553843 48282 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 2 5 5.3 O=C(COc1ccc(Cl)cc1)Nc1ccc(O)c(-c2nc3ccccc3s2)c1 nan
5302298 48292 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 2 2 5 5.5 Nc1c(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)sc2nc3c(cc12)N1CCC3CC1 nan
CHEMBL1554006 48292 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 2 2 5 5.5 Nc1c(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)sc2nc3c(cc12)N1CCC3CC1 nan
16018784 48306 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 1 8 3.8 CCc1nnc(SCC(=O)Nc2ccc(OC)c(OC)c2)c2cc3occc3n12 nan
CHEMBL1554189 48306 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 1 8 3.8 CCc1nnc(SCC(=O)Nc2ccc(OC)c(OC)c2)c2cc3occc3n12 nan
16018201 48347 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 3 3.8 Cc1ccc2c(c1)N(C(=O)N1CCC(C(=O)NCCc3ccccc3)CC1)CC(C)O2 nan
CHEMBL1554848 48347 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 3 3.8 Cc1ccc2c(c1)N(C(=O)N1CCC(C(=O)NCCc3ccccc3)CC1)CC(C)O2 nan
3151378 48423 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 2 7 2.9 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCCC4)c3nc12 nan
CHEMBL1555780 48423 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 2 7 2.9 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCCC4)c3nc12 nan
16019891 48625 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 6 0 9 5.1 CCC(=O)Oc1cc(C(C)(C)C)cc2cc(-c3nc(-c4ccc(OC)cc4OC)no3)c(=O)oc12 nan
CHEMBL1557596 48625 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 6 0 9 5.1 CCC(=O)Oc1cc(C(C)(C)C)cc2cc(-c3nc(-c4ccc(OC)cc4OC)no3)c(=O)oc12 nan
3239255 48715 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 7 3.8 COc1ccc(-c2nn(C)c3sc(C(=O)NCc4ccco4)cc23)cc1OC nan
CHEMBL1558431 48715 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 7 3.8 COc1ccc(-c2nn(C)c3sc(C(=O)NCc4ccco4)cc23)cc1OC nan
662047 48878 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 7 3.8 COc1cccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1559829 48878 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 7 3.8 COc1cccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
2612492 49031 5 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 1 7 3.9 Cc1nc(SCC(=O)Nc2cc(C)on2)c2c3c(sc2n1)CCCC3 nan
CHEMBL1561287 49031 5 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 1 7 3.9 Cc1nc(SCC(=O)Nc2cc(C)on2)c2c3c(sc2n1)CCCC3 nan
670483 49041 38 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 2 1 4 3.4 Fc1cccc(-c2nnc(S)n2-c2ccccc2)c1 nan
CHEMBL1561393 49041 38 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 2 1 4 3.4 Fc1cccc(-c2nnc(S)n2-c2ccccc2)c1 nan
16025728 49148 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 6 5.8 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3C)s1)C2 nan
CHEMBL1562331 49148 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 6 5.8 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3C)s1)C2 nan
135788252 49195 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 8 3.1 COC(=O)c1cc(-c2ccc(OC)cc2F)nc2nc(SC)nc(O)c12 nan
CHEMBL1562765 49195 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 8 3.1 COC(=O)c1cc(-c2ccc(OC)cc2F)nc2nc(SC)nc(O)c12 nan
20956964 49196 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 0 9 0.6 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)CC1 nan
CHEMBL1562772 49196 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 0 9 0.6 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)CC1 nan
15988783 49241 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 7 1 10 2.8 Cc1sc2ncn(CC(=O)Nc3ccc(C(C)C)cc3)c(=O)c2c1S(=O)(=O)N1CCN(c2ncccn2)CC1 nan
CHEMBL1563146 49241 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 7 1 10 2.8 Cc1sc2ncn(CC(=O)Nc3ccc(C(C)C)cc3)c(=O)c2c1S(=O)(=O)N1CCN(c2ncccn2)CC1 nan
20923169 49298 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 0 6 2.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)CC(C)C1 nan
CHEMBL1563711 49298 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 0 6 2.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)CC(C)C1 nan
16009570 49434 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1cn2c(=O)cc(COc3cccc(NC(=O)c4ccccc4C)c3)nc2s1 nan
CHEMBL1564898 49434 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1cn2c(=O)cc(COc3cccc(NC(=O)c4ccccc4C)c3)nc2s1 nan
22517528 49446 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 3.0 CC1CCN(S(=O)(=O)c2nnc(NC(=O)c3ccccc3Br)s2)CC1 nan
CHEMBL1564984 49446 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 3.0 CC1CCN(S(=O)(=O)c2nnc(NC(=O)c3ccccc3Br)s2)CC1 nan
16001900 49888 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 8 2 8 3.6 COc1ccc(CCNc2nc(S)nc3cc(OC)c(OC)cc23)cc1OC nan
CHEMBL1568426 49888 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 8 2 8 3.6 COc1ccc(CCNc2nc(S)nc3cc(OC)c(OC)cc23)cc1OC nan
2952518 49957 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 571 9 3 9 6.0 CCOc1ccccc1NC(=O)CSC1=C(C#N)C(c2ccco2)C(C(=O)Nc2nc3ccccc3s2)=C(C)N1 nan
CHEMBL1569028 49957 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 571 9 3 9 6.0 CCOc1ccccc1NC(=O)CSC1=C(C#N)C(c2ccco2)C(C(=O)Nc2nc3ccccc3s2)=C(C)N1 nan
18562928 49971 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 8 1 8 2.2 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCCCC4)nn23)cc1 nan
CHEMBL1569159 49971 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 8 1 8 2.2 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCCCC4)nn23)cc1 nan
3152775 50196 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 4 2 7 5.0 Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccc(C)o4)C3c3ccc(O)cc3)sc2c1 nan
CHEMBL1571071 50196 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 4 2 7 5.0 Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccc(C)o4)C3c3ccc(O)cc3)sc2c1 nan
3564285 50489 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 5 4.3 CN(C)CCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1cccc(Br)c1 nan
5036767 50489 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 5 4.3 CN(C)CCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1cccc(Br)c1 nan
CHEMBL1573867 50489 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 5 4.3 CN(C)CCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1cccc(Br)c1 nan
1325969 50501 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 0 7 5.3 COc1cc(-c2nnc(COc3ccc4cc(Br)ccc4c3)o2)cc(OC)c1OC nan
CHEMBL1574014 50501 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 0 7 5.3 COc1cc(-c2nnc(COc3ccc4cc(Br)ccc4c3)o2)cc(OC)c1OC nan
3613213 50666 11 None -1000 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 2 3 4.6 O=C(O)CC(NC(=O)c1sc2ccccc2c1Cl)c1ccc(F)cc1 nan
CHEMBL1575774 50666 11 None -1000 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 2 3 4.6 O=C(O)CC(NC(=O)c1sc2ccccc2c1Cl)c1ccc(F)cc1 nan
2352763 50694 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 5 1 4 2.6 NC(=O)COC(=O)CSc1cccc2cccc(Cl)c12 nan
CHEMBL1576037 50694 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 5 1 4 2.6 NC(=O)COC(=O)CSc1cccc2cccc(Cl)c12 nan
135433192 50986 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 1 4 3.8 Oc1nc(SCc2ccccc2F)nc2ccccc12 nan
CHEMBL1578484 50986 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 1 4 3.8 Oc1nc(SCc2ccccc2F)nc2ccccc12 nan
18107118 51004 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 5 2.9 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)Nc1ccccn1 nan
CHEMBL1578588 51004 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 5 2.9 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)Nc1ccccn1 nan
1838209 51050 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 2 8 1.2 N#C/C(=C\c1c(N2CCC(C(N)=O)CC2)nc2ccccn2c1=O)C(=O)NCc1ccco1 nan
CHEMBL1578976 51050 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 2 8 1.2 N#C/C(=C\c1c(N2CCC(C(N)=O)CC2)nc2ccccn2c1=O)C(=O)NCc1ccco1 nan
3802907 51117 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 1 6 4.1 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Br)c1)c1cc2ccccc2o1 nan
4542697 51117 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 1 6 4.1 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Br)c1)c1cc2ccccc2o1 nan
CHEMBL1579576 51117 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 1 6 4.1 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Br)c1)c1cc2ccccc2o1 nan
16196197 51129 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 4 6.4 Cc1cc(/C(O)=C(/C([S-])=Nc2ccc(F)cc2)[n+]2ccccc2)c(C)n1Cc1ccccc1Cl nan
3610394 51129 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 4 6.4 Cc1cc(/C(O)=C(/C([S-])=Nc2ccc(F)cc2)[n+]2ccccc2)c(C)n1Cc1ccccc1Cl nan
CHEMBL1579745 51129 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 4 6.4 Cc1cc(/C(O)=C(/C([S-])=Nc2ccc(F)cc2)[n+]2ccccc2)c(C)n1Cc1ccccc1Cl nan
2357568 51147 6 None -5 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 6 4.7 O=C(CSc1nnc(-c2cccs2)n1-c1ccccc1)Nc1ccccc1 nan
CHEMBL1579942 51147 6 None -5 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 6 4.7 O=C(CSc1nnc(-c2cccs2)n1-c1ccccc1)Nc1ccccc1 nan
4831734 51177 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 7 1 6 3.8 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2c3c(nc4ccccc24)CCC3)c1 nan
CHEMBL1580173 51177 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 7 1 6 3.8 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2c3c(nc4ccccc24)CCC3)c1 nan
1476967 51209 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 0 6 2.0 c1cn(-c2ccc(-c3ccnc4ncnn34)cc2)cn1 nan
CHEMBL1580435 51209 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 0 6 2.0 c1cn(-c2ccc(-c3ccnc4ncnn34)cc2)cn1 nan
7190795 51222 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 0 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)c1ccccc1 nan
CHEMBL1580576 51222 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 0 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)c1ccccc1 nan
16194926 51297 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 7 2.5 Cc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
CHEMBL1581174 51297 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 7 2.5 Cc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
3357076 51374 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 5 3.4 CCN(CC)S(=O)(=O)c1ccc(N2CCCCC2)c(NC(=O)c2ccncc2)c1 nan
CHEMBL1581844 51374 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 5 3.4 CCN(CC)S(=O)(=O)c1ccc(N2CCCCC2)c(NC(=O)c2ccncc2)c1 nan
3151315 51528 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 8 1.9 Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1583158 51528 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 8 1.9 Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)c(=N)n(CC4CCCO4)c3nc12 nan
3721854 51646 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 2 1 7 2.1 Nc1c(C(=O)N2CCOCC2)sc2nc(N3CCOCC3)c3c(c12)CCCC3 nan
CHEMBL1584034 51646 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 2 1 7 2.1 Nc1c(C(=O)N2CCOCC2)sc2nc(N3CCOCC3)c3c(c12)CCCC3 nan
3911608 51754 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 4.5 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1 nan
CHEMBL1584955 51754 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 4.5 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1 nan
7207569 51933 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 1 7 1.8 O=C(NCCc1nnc2ccc(SCC(=O)N3CCCC3)nn12)c1ccccc1 nan
CHEMBL1586420 51933 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 1 7 1.8 O=C(NCCc1nnc2ccc(SCC(=O)N3CCCC3)nn12)c1ccccc1 nan
7190486 52031 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
CHEMBL1587249 52031 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
5225306 52067 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.9 CC1CCCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1587533 52067 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.9 CC1CCCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
4975167 52080 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 7 1 5 3.1 CCCc1cc(=O)oc2c(C)c(OCC(=O)NCc3ccccn3)ccc12 nan
CHEMBL1587597 52080 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 7 1 5 3.1 CCCc1cc(=O)oc2c(C)c(OCC(=O)NCc3ccccn3)ccc12 nan
5236958 52261 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 2.7 CCN(CC)S(=O)(=O)c1ccc(Cl)c(NC(=O)CSc2cccc[n+]2[O-])c1 nan
CHEMBL1589189 52261 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 2.7 CCN(CC)S(=O)(=O)c1ccc(Cl)c(NC(=O)CSc2cccc[n+]2[O-])c1 nan
16022898 52346 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 7 1 6 2.7 CCOCCCNc1nc2ccccc2n2c(CC)nnc12 nan
CHEMBL1589922 52346 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 7 1 6 2.7 CCOCCCNc1nc2ccccc2n2c(CC)nnc12 nan
16009827 52357 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1OC nan
CHEMBL1590063 52357 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1OC nan
1391194 52427 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 4 3.9 O=C(O)CCNc1nc(-c2ccccc2)c2cc(Br)ccc2n1 nan
1391195 52427 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 4 3.9 O=C(O)CCNc1nc(-c2ccccc2)c2cc(Br)ccc2n1 nan
CHEMBL1590944 52427 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 4 3.9 O=C(O)CCNc1nc(-c2ccccc2)c2cc(Br)ccc2n1 nan
18572144 52450 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 2 6 2.6 Cn1c(SCC(=O)NCCc2ccccc2)ncc(C(=O)Nc2ccc(F)cc2)c1=O nan
CHEMBL1591283 52450 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 2 6 2.6 Cn1c(SCC(=O)NCCc2ccccc2)ncc(C(=O)Nc2ccc(F)cc2)c1=O nan
20903635 52474 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 0 9 1.9 CCCN1CCN(C(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)CC1 nan
CHEMBL1591509 52474 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 0 9 1.9 CCCN1CCN(C(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)CC1 nan
16012276 52497 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 5 2.3 Cc1cc(C)n2nc(CNC(=O)c3ccc(Cl)cc3)nc2n1 nan
CHEMBL1591819 52497 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 5 2.3 Cc1cc(C)n2nc(CNC(=O)c3ccc(Cl)cc3)nc2n1 nan
5303336 52531 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 1 5 4.2 CCOc1ccc(-c2oc3cc(Cl)ccc3c(=O)c2O)cc1OC nan
CHEMBL1592283 52531 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 1 5 4.2 CCOc1ccc(-c2oc3cc(Cl)ccc3c(=O)c2O)cc1OC nan
2790635 52641 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 2 4 4.1 Cc1ccc(OCCCC(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)cc1 nan
CHEMBL1593935 52641 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 2 4 4.1 Cc1ccc(OCCCC(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)cc1 nan
3476583 52825 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3F)n2)cc1 nan
CHEMBL1595488 52825 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3F)n2)cc1 nan
1958370 52843 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 7 2.5 COCCNS(=O)(=O)c1cc(-c2nn3c(C)nnc3c3ccccc23)ccc1C nan
CHEMBL1595653 52843 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 7 2.5 COCCNS(=O)(=O)c1cc(-c2nn3c(C)nnc3c3ccccc23)ccc1C nan
4601439 53017 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 2 7 3.9 COc1cccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)c1 nan
CHEMBL1597228 53017 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 2 7 3.9 COc1cccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)c1 nan
4151069 53230 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 10 0.6 COC(=O)c1cc(NS(=O)(=O)c2ccc3c(c2)c(=O)n(C)c(=O)n3C)cc(C(=O)OC)c1 nan
CHEMBL1599214 53230 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 10 0.6 COC(=O)c1cc(NS(=O)(=O)c2ccc3c(c2)c(=O)n(C)c(=O)n3C)cc(C(=O)OC)c1 nan
2890665 53302 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 3 1 3 3.6 CC(=O)C1=C(O)C(=O)N(c2ccc(F)cc2)C1c1ccc(C)cc1 nan
CHEMBL1599834 53302 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 3 1 3 3.6 CC(=O)C1=C(O)C(=O)N(c2ccc(F)cc2)C1c1ccc(C)cc1 nan
16020305 53620 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 12 1 6 4.3 CCCN(CCC)C(=O)Cn1c(=O)n(-c2ccc(CC)cc2)c(=O)c2ccc(C(=O)NCCc3ccccc3)cc21 nan
CHEMBL1602912 53620 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 12 1 6 4.3 CCCN(CCC)C(=O)Cn1c(=O)n(-c2ccc(CC)cc2)c(=O)c2ccc(C(=O)NCCc3ccccc3)cc21 nan
910705 53707 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 2 0 4 2.4 O=[N+]([O-])c1ccc(-c2cn3c(n2)CCC3)cc1 nan
CHEMBL1603668 53707 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 2 0 4 2.4 O=[N+]([O-])c1ccc(-c2cn3c(n2)CCC3)cc1 nan
1146176 53856 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 0 4 4.7 CC1CCN(C(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)n2)CC1 nan
CHEMBL1604923 53856 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 0 4 4.7 CC1CCN(C(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)n2)CC1 nan
16019480 53946 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 0 9 2.9 CCc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCN(CC)CC2)c2sccc23)cc1 nan
CHEMBL1605620 53946 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 0 9 2.9 CCc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCN(CC)CC2)c2sccc23)cc1 nan
1410148 54061 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.5 CCOc1ccc(C(=O)Nc2ccc3oc(-c4cccnc4)nc3c2)cc1 nan
CHEMBL1606536 54061 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.5 CCOc1ccc(C(=O)Nc2ccc3oc(-c4cccnc4)nc3c2)cc1 nan
2918495 54093 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 8 2.5 COc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1OC nan
CHEMBL1606762 54093 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 8 2.5 COc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1OC nan
5730347 54143 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 4 0 4 3.9 CCC(=O)c1ccc(/C=C/c2nc3ccccc3n2C)o1 nan
CHEMBL1607132 54143 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 4 0 4 3.9 CCC(=O)c1ccc(/C=C/c2nc3ccccc3n2C)o1 nan
4426797 54227 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 10 -0.6 Cn1c(=O)c2c(nc(CN3CCN(C(=O)c4ccco4)CC3)n2CCCO)n(C)c1=O nan
CHEMBL1607800 54227 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 10 -0.6 Cn1c(=O)c2c(nc(CN3CCN(C(=O)c4ccco4)CC3)n2CCCO)n(C)c1=O nan
1325691 54260 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 1 1 7 3.2 Sc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CCCC3 nan
CHEMBL1608119 54260 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 1 1 7 3.2 Sc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CCCC3 nan
2966904 54264 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 7 2 7 3.4 CC(=O)c1sc2nc(SCC(=O)NCCc3ccccc3)nc(O)c2c1C nan
CHEMBL1608140 54264 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 7 2 7 3.4 CC(=O)c1sc2nc(SCC(=O)NCCc3ccccc3)nc(O)c2c1C nan
16406841 54270 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 3 0 6 3.1 Cc1c(Br)c(=O)oc2cc(OCC(=O)N3C[C@@H]4C[C@H](C3)Cn3c4cccc3=O)ccc12 nan
CHEMBL1608190 54270 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 3 0 6 3.1 Cc1c(Br)c(=O)oc2cc(OCC(=O)N3C[C@@H]4C[C@H](C3)Cn3c4cccc3=O)ccc12 nan
54686430 54335 31 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 2 4 1.8 CCCNC(=O)c1c(O)c2cccc3c2n(c1=O)CCC3 nan
CHEMBL1608771 54335 31 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 2 4 1.8 CCCNC(=O)c1c(O)c2cccc3c2n(c1=O)CCC3 nan
6107794 54393 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 7 1 7 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)c(OC)c1 nan
CHEMBL1609202 54393 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 7 1 7 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)c(OC)c1 nan
2576098 54425 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 5 1 5 2.7 Cc1sc2ncnc(NCCCN3CCCC3=O)c2c1C nan
CHEMBL1609414 54425 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 5 1 5 2.7 Cc1sc2ncnc(NCCCN3CCCC3=O)c2c1C nan
3641030 54481 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 1 3 5.1 CC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(Cl)cc3)o2)cc1 nan
CHEMBL1609950 54481 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 1 3 5.1 CC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(Cl)cc3)o2)cc1 nan
2868074 54499 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 1 3 4.7 CC(=O)C1=C(O)C(=O)N(c2cccc(Br)c2)C1c1ccc(Br)cc1 nan
CHEMBL1610073 54499 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 1 3 4.7 CC(=O)C1=C(O)C(=O)N(c2cccc(Br)c2)C1c1ccc(Br)cc1 nan
2790804 54610 18 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 6 3.8 O=[N+]([O-])c1ccc(-c2nc(NCC3CCCO3)c3ccccc3n2)cc1 nan
CHEMBL1611050 54610 18 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 6 3.8 O=[N+]([O-])c1ccc(-c2nc(NCC3CCCO3)c3ccccc3n2)cc1 nan
2934073 54861 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1cccc(Cl)c1)c1ccco1 nan
CHEMBL1613356 54861 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1cccc(Cl)c1)c1ccco1 nan
4581262 55297 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 4.4 CC1CCN(CCCn2c(=S)[nH]c3c(sc4ccccc43)c2=O)CC1 nan
CHEMBL1377318 55297 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 4.4 CC1CCN(CCCn2c(=S)[nH]c3c(sc4ccccc43)c2=O)CC1 nan
CHEMBL1618739 55297 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 4.4 CC1CCN(CCCn2c(=S)[nH]c3c(sc4ccccc43)c2=O)CC1 nan
1099157 55323 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 4 4.4 O=C(CN1CCCCC1)Nc1c2c(nc3ccccc13)N(c1ccccc1)CC2 nan
CHEMBL1389219 55323 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 4 4.4 O=C(CN1CCCCC1)Nc1c2c(nc3ccccc13)N(c1ccccc1)CC2 nan
CHEMBL1618947 55323 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 4 4.4 O=C(CN1CCCCC1)Nc1c2c(nc3ccccc13)N(c1ccccc1)CC2 nan
4055296 55450 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 5.8 O=[N+]([O-])c1cccc(-c2cc3sc4ccccc4[n+]3cc2-c2cccc([N+](=O)[O-])c2)c1 nan
CHEMBL1420869 55450 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 5.8 O=[N+]([O-])c1cccc(-c2cc3sc4ccccc4[n+]3cc2-c2cccc([N+](=O)[O-])c2)c1 nan
CHEMBL1620041 55450 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 5.8 O=[N+]([O-])c1cccc(-c2cc3sc4ccccc4[n+]3cc2-c2cccc([N+](=O)[O-])c2)c1 nan
655842 55598 11 None -12 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 5 3.0 CSCCC(Nc1ncnc2ccc(Br)cc12)C(=O)O nan
CHEMBL1466356 55598 11 None -12 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 5 3.0 CSCCC(Nc1ncnc2ccc(Br)cc12)C(=O)O nan
CHEMBL1621365 55598 11 None -12 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 5 3.0 CSCCC(Nc1ncnc2ccc(Br)cc12)C(=O)O nan
3848238 55974 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 5 5.5 N#Cc1c(SC(C(=O)O)c2ccccc2)nc2c(c1-c1cccs1)CCCC2 nan
CHEMBL1548688 55974 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 5 5.5 N#Cc1c(SC(C(=O)O)c2ccccc2)nc2c(c1-c1cccs1)CCCC2 nan
CHEMBL1624498 55974 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 5 5.5 N#Cc1c(SC(C(=O)O)c2ccccc2)nc2c(c1-c1cccs1)CCCC2 nan
3589783 55987 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 2 6 5.1 CC1(C)CC2=NC3=C(C(=O)c4ccccc43)C(c3cc([N+](=O)[O-])ccc3O)C2=C(O)C1 nan
CHEMBL1566042 55987 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 2 6 5.1 CC1(C)CC2=NC3=C(C(=O)c4ccccc43)C(c3cc([N+](=O)[O-])ccc3O)C2=C(O)C1 nan
CHEMBL1624662 55987 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 2 6 5.1 CC1(C)CC2=NC3=C(C(=O)c4ccccc43)C(c3cc([N+](=O)[O-])ccc3O)C2=C(O)C1 nan
9560158 72169 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 9 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1980603 72169 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 9 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
9624156 72243 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 5 4.4 N#CCC(=O)N/N=C/c1ccc(N2N=C(c3ccccc3)CC2c2ccccc2)cc1 nan
CHEMBL1982521 72243 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 5 4.4 N#CCC(=O)N/N=C/c1ccc(N2N=C(c3ccccc3)CC2c2ccccc2)cc1 nan
1995859 72774 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 7 1.3 COCCCn1/c(=N/C(C)=O)c(C#N)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL2000901 72774 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 7 1.3 COCCCn1/c(=N/C(C)=O)c(C#N)cc2c(=O)n3cccc(C)c3nc21 nan
65599 105395 45 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL311948 105395 45 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1cnc2c1c(=O)n(C)c(=O)n2C nan
2864416 106859 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 7 1.6 Cc1[nH]n(-c2ccc([N+](=O)[O-])cc2)c(=O)c1/C=N/CCN1CCN(C(=O)C(C)C)CC1 nan
CHEMBL3145301 106859 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 7 1.6 Cc1[nH]n(-c2ccc([N+](=O)[O-])cc2)c(=O)c1/C=N/CCN1CCN(C(=O)C(C)C)CC1 nan
5935610 107580 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 1 1 3 3.9 CCn1c2c(c3cc(Br)ccc31)CCC/C2=N\O nan
CHEMBL3189713 107580 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 1 1 3 3.9 CCn1c2c(c3cc(Br)ccc31)CCC/C2=N\O nan
6279969 107857 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 0 6 2.1 CN(C)/C=N/c1nc2nccc(-c3cccs3)n2n1 nan
CHEMBL3192852 107857 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 0 6 2.1 CN(C)/C=N/c1nc2nccc(-c3cccs3)n2n1 nan
6860035 108089 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 7 1 8 3.0 COc1ccc(OC)c(/C=N/n2c(S)nnc2COc2ccccc2)c1 nan
CHEMBL3195667 108089 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 7 1 8 3.0 COc1ccc(OC)c(/C=N/n2c(S)nnc2COc2ccccc2)c1 nan
135467322 108670 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 6 4.3 COC(=O)/C(Nc1ccccc1)=C(\C(=O)C(=O)N(C)c1ccccc1)C(=O)c1ccc(Cl)cc1 nan
CHEMBL3208147 108670 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 6 4.3 COC(=O)/C(Nc1ccccc1)=C(\C(=O)C(=O)N(C)c1ccccc1)C(=O)c1ccc(Cl)cc1 nan
2805193 108783 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 5 1 7 2.6 CCO/C(O)=C(C#N)/C=N/c1ccsc1C(=O)OC nan
CHEMBL3209558 108783 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 5 1 7 2.6 CCO/C(O)=C(C#N)/C=N/c1ccsc1C(=O)OC nan
5867179 108991 3 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.1 C/C(N)=C(/C#N)C(=O)COC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL3212349 108991 3 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.1 C/C(N)=C(/C#N)C(=O)COC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
3221537 112592 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 0 5 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\C)S3 nan
CHEMBL3209727 112592 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 0 5 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\C)S3 nan
CHEMBL3302425 112592 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 0 5 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\C)S3 nan
264006 178539 13 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 4 9 -1.0 C=CCNc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
CHEMBL46703 178539 13 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 4 9 -1.0 C=CCNc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
833435 197647 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 3 4 2.9 Cc1sc(NC(=S)NC(=O)C2CCCCC2)c(C(N)=O)c1C nan
CHEMBL571065 197647 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 3 4 2.9 Cc1sc(NC(=S)NC(=O)C2CCCCC2)c(C(N)=O)c1C nan
22334103 200886 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 513 9 2 8 1.6 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1Cl nan
CHEMBL601585 200886 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 513 9 2 8 1.6 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1Cl nan
4167655 28219 10 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.3 Brc1ccc(-c2nnc3sc(CNC4CCCC4)cn23)cc1 nan
CHEMBL1374064 28219 10 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.3 Brc1ccc(-c2nnc3sc(CNC4CCCC4)cn23)cc1 nan
16018920 28454 6 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 6 4.8 CCc1nnc(SCC(=O)Nc2ccc(F)cc2F)c2cc3sc(C)cc3n12 nan
CHEMBL1375688 28454 6 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 6 4.8 CCc1nnc(SCC(=O)Nc2ccc(F)cc2F)c2cc3sc(C)cc3n12 nan
3348974 39162 10 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 11 0.5 CCc1nnc(NC(=O)CSc2nc(C)nc3c2c(=O)n(C)c(=O)n3C)s1 nan
CHEMBL1469832 39162 10 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 11 0.5 CCc1nnc(NC(=O)CSc2nc(C)nc3c2c(=O)n(C)c(=O)n3C)s1 nan
4351083 47137 8 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 8 3.0 O=C(NN1C(=O)c2ccccc2NC1c1ccc([N+](=O)[O-])o1)c1ccc([N+](=O)[O-])cc1 nan
CHEMBL1543122 47137 8 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 8 3.0 O=C(NN1C(=O)c2ccccc2NC1c1ccc([N+](=O)[O-])o1)c1ccc([N+](=O)[O-])cc1 nan
3241486 49894 6 None 1 2 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 6 1 6 4.2 COc1ccc(C(=O)Nc2ccc(N3CCN(c4ccc(OC)cc4)CC3)c(C#N)c2)cc1 nan
CHEMBL1568468 49894 6 None 1 2 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 6 1 6 4.2 COc1ccc(C(=O)Nc2ccc(N3CCN(c4ccc(OC)cc4)CC3)c(C#N)c2)cc1 nan
1261644 50050 10 None 1 2 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 3 1 4 4.7 O=C(Nc1ccncc1)c1cc(-c2ccccn2)nc2ccc(Br)cc12 nan
CHEMBL1569872 50050 10 None 1 2 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 3 1 4 4.7 O=C(Nc1ccncc1)c1cc(-c2ccccn2)nc2ccc(Br)cc12 nan
759120 52533 34 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 1 3 4.4 O=C(O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1592299 52533 34 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 1 3 4.4 O=C(O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
16010305 7641 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 3.2 COCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccc(Cl)cc12 nan
CHEMBL1088575 7641 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 3.2 COCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccc(Cl)cc12 nan
16019548 10850 10 None -23 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 8 4.4 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(Cl)cc1)c1sccc12 nan
CHEMBL1172597 10850 10 None -23 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 8 4.4 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(Cl)cc1)c1sccc12 nan
16019364 10925 6 None -53 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 1 8 4.5 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccc(F)cc2)c2sccc23)cc1C nan
CHEMBL1173283 10925 6 None -53 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 1 8 4.5 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccc(F)cc2)c2sccc23)cc1C nan
5721990 14794 23 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 3 0 2 4.5 CN(C)c1ccc(/C=C/c2ccc3ccccc3n2)cc1 nan
CHEMBL120734 14794 23 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 3 0 2 4.5 CN(C)c1ccc(/C=C/c2ccc3ccccc3n2)cc1 nan
3565 19340 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 2 2 2.2 CC1=NCCc2c1[nH]c1cc(O)ccc21 nan
CHEMBL129177 19340 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 2 2 2.2 CC1=NCCc2c1[nH]c1cc(O)ccc21 nan
CHEMBL1473205 19340 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 2 2 2.2 CC1=NCCc2c1[nH]c1cc(O)ccc21 nan
2803232 19487 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 2 2 4.3 S=C(Nc1ccccc1)Nc1ccccc1-n1cccc1 nan
CHEMBL1299459 19487 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 2 2 4.3 S=C(Nc1ccccc1)Nc1ccccc1-n1cccc1 nan
1305405 19643 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 3 4 4.4 O=C(O)c1ccccc1NC(=S)NC(=O)c1sc2ccccc2c1Cl nan
CHEMBL1300720 19643 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 3 4 4.4 O=C(O)c1ccccc1NC(=S)NC(=O)c1sc2ccccc2c1Cl nan
24790327 19678 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 0 5 4.4 COc1ccc2cc(C(=O)C3CCCN(C(=O)c4cnn(C(C)C)c4)C3)ccc2c1 nan
CHEMBL1300972 19678 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 0 5 4.4 COc1ccc2cc(C(=O)C3CCCN(C(=O)c4cnn(C(C)C)c4)C3)ccc2c1 nan
5826640 19746 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 10 1 7 4.1 CCCCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1301431 19746 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 10 1 7 4.1 CCCCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
2410711 19765 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 5 3.5 CCOc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)cc1 nan
CHEMBL1301615 19765 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 5 3.5 CCOc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)cc1 nan
5918716 19834 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 7 0.8 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NC)CC1 nan
CHEMBL1302267 19834 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 7 0.8 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NC)CC1 nan
910973 19961 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 1 2 6 1.6 N#CC(C#N)=C1NC(N)=C(C#N)C(c2ccccc2)=C1C#N nan
CHEMBL1303255 19961 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 1 2 6 1.6 N#CC(C#N)=C1NC(N)=C(C#N)C(c2ccccc2)=C1C#N nan
2472728 20135 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 1 7 2.7 Cc1sc2ncnc(SCC(=O)NC(=O)c3cccn3C)c2c1C nan
CHEMBL1304667 20135 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 1 7 2.7 Cc1sc2ncnc(SCC(=O)NC(=O)c3cccn3C)c2c1C nan
3544771 20157 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 0 9 3.2 O=c1c2sccc2nc(SCc2cc(=O)n3ccccc3n2)n1Cc1ccccn1 nan
CHEMBL1304859 20157 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 0 9 3.2 O=c1c2sccc2nc(SCc2cc(=O)n3ccccc3n2)n1Cc1ccccn1 nan
7295015 20297 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 5 3.6 CSc1ccccc1-c1nnc(NC(=O)Cc2ccccc2)o1 nan
CHEMBL1305973 20297 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 5 3.6 CSc1ccccc1-c1nnc(NC(=O)Cc2ccccc2)o1 nan
654420 20300 5 None -28 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 5 0 5 2.8 CCOC(=O)CSc1nc(CC)nc2ccccc12 nan
CHEMBL1305990 20300 5 None -28 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 5 0 5 2.8 CCOC(=O)CSc1nc(CC)nc2ccccc12 nan
4021231 20310 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 2 7 2.7 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc(F)cc4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1306067 20310 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 2 7 2.7 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc(F)cc4)c(=N)n(CC4CCCO4)c3nc12 nan
833786 20361 14 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 3 1 4 4.2 Sc1nc(SCc2ccccc2)nc2ccccc12 nan
CHEMBL1306480 20361 14 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 3 1 4 4.2 Sc1nc(SCc2ccccc2)nc2ccccc12 nan
865618 20372 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 0 4 3.6 CN(C)c1ccc(-c2nnc(-c3ccccc3F)o2)cc1 nan
CHEMBL1306590 20372 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 0 4 3.6 CN(C)c1ccc(-c2nnc(-c3ccccc3F)o2)cc1 nan
6078291 20479 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 4.6 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1307444 20479 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 4.6 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
2820469 20558 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 3.4 CSc1sc(C(=O)NCC2CC2)c2c1S(=O)(=O)N(C)c1ccccc1-2 nan
CHEMBL1308054 20558 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 3.4 CSc1sc(C(=O)NCC2CC2)c2c1S(=O)(=O)N(C)c1ccccc1-2 nan
5012705 20568 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 9 2 6 3.7 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCCc1ccccc1 nan
CHEMBL1308124 20568 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 9 2 6 3.7 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCCc1ccccc1 nan
1201985 20718 9 None -2 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 0 6 3.8 O=C(CSc1nc2ccccc2nc1SCC(=O)N1CCCCC1)N1CCCCC1 nan
CHEMBL1309335 20718 9 None -2 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 0 6 3.8 O=C(CSc1nc2ccccc2nc1SCC(=O)N1CCCCC1)N1CCCCC1 nan
24891893 20726 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 9 -0.0 CCc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1309394 20726 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 9 -0.0 CCc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
1596915 20740 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 2 7 4.6 Cc1csc(NC(=O)c2sc3nc(-c4cccs4)ccc3c2N)n1 nan
CHEMBL1309478 20740 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 2 7 4.6 Cc1csc(NC(=O)c2sc3nc(-c4cccs4)ccc3c2N)n1 nan
3236246 20822 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 7 1 8 2.8 CCC(Sc1ccc2nnc(-c3ccc(OC)c(OC)c3)n2n1)C(=O)O nan
CHEMBL1310295 20822 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 7 1 8 2.8 CCC(Sc1ccc2nnc(-c3ccc(OC)c(OC)c3)n2n1)C(=O)O nan
4881170 20929 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 0 6 3.0 Cc1nc(SC2CCOC2=O)c2c(C)c(C)sc2n1 nan
CHEMBL1311178 20929 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 0 6 3.0 Cc1nc(SC2CCOC2=O)c2c(C)c(C)sc2n1 nan
5813760 20975 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 5 1 6 4.4 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccc(Br)cc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1311567 20975 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 5 1 6 4.4 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccc(Br)cc1)c1ccc2c(c1)OCCO2 nan
3682235 21050 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1312109 21050 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
3588555 21129 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 580 5 1 8 3.8 Cc1cc(Br)ccc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
CHEMBL1312634 21129 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 580 5 1 8 3.8 Cc1cc(Br)ccc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
2332949 21140 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 2 5 4.7 Cc1ccc(-c2c(C#N)c(S)nc(C)c2C(=O)Nc2ccccc2C)o1 nan
CHEMBL1312698 21140 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 2 5 4.7 Cc1ccc(-c2c(C#N)c(S)nc(C)c2C(=O)Nc2ccccc2C)o1 nan
20957089 21149 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 8 1 9 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCc4ccco4)nn23)CC1 nan
CHEMBL1312760 21149 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 8 1 9 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCc4ccco4)nn23)CC1 nan
7064857 21441 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 5.1 CCc1cccc(C)c1Nc1c(-c2ccc(N(C)C)cc2)nc2cnccn12 nan
CHEMBL1315626 21441 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 5.1 CCc1cccc(C)c1Nc1c(-c2ccc(N(C)C)cc2)nc2cnccn12 nan
16299684 21452 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 7 2.8 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(NC(=O)c2nn(C)c(=O)c3ccccc23)c1 nan
CHEMBL1315774 21452 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 7 2.8 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(NC(=O)c2nn(C)c(=O)c3ccccc23)c1 nan
16010795 21462 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 8 1 8 2.8 COc1ccc(CCn2c(=O)c3cccnc3n(CC(=O)Nc3cccc(C)c3)c2=O)cc1OC nan
CHEMBL1315899 21462 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 8 1 8 2.8 COc1ccc(CCn2c(=O)c3cccnc3n(CC(=O)Nc3cccc(C)c3)c2=O)cc1OC nan
16018148 21542 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 4 4.4 CCn1cc2c(n1)-c1c(oc(C(=O)Nc3cccc(C)c3C)c1C)CC2 nan
CHEMBL1316992 21542 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 4 4.4 CCn1cc2c(n1)-c1c(oc(C(=O)Nc3cccc(C)c3C)c1C)CC2 nan
5921518 21600 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 1 8 2.1 COCCCNC(=O)/C(C#N)=C/c1c(N2CCN(c3ccccc3)CC2)nc2ccccn2c1=O nan
CHEMBL1317700 21600 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 1 8 2.1 COCCCNC(=O)/C(C#N)=C/c1c(N2CCN(c3ccccc3)CC2)nc2ccccn2c1=O nan
4062026 21647 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 4 1 6 4.5 Cc1ccc(Cl)cc1NC(=O)c1oc2ccc(S(=O)(=O)N3CCC4(CC3)OCCO4)cc2c1C nan
CHEMBL1318364 21647 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 4 1 6 4.5 Cc1ccc(Cl)cc1NC(=O)c1oc2ccc(S(=O)(=O)N3CCC4(CC3)OCCO4)cc2c1C nan
16027568 21648 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)c1 nan
CHEMBL1318374 21648 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)c1 nan
16028281 21662 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 7 3.4 CCc1cccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)c1 nan
CHEMBL1318465 21662 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 7 3.4 CCc1cccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)c1 nan
16017220 21683 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 8 1 6 4.8 Cc1nn(CCCC(=O)NCc2ccc(OC(C)C)cc2)c(=O)c2c1sc1ccccc12 nan
CHEMBL1318645 21683 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 8 1 6 4.8 Cc1nn(CCCC(=O)NCc2ccc(OC(C)C)cc2)c(=O)c2c1sc1ccccc12 nan
16027652 21734 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 9 1 8 4.3 CC(C)Cc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
CHEMBL1319006 21734 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 9 1 8 4.3 CC(C)Cc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
2998240 21841 5 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 1 5 4.2 O=C(NCc1ccc(Cl)cc1)c1cc2c(nc3sccn32)s1 nan
CHEMBL1319990 21841 5 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 1 5 4.2 O=C(NCc1ccc(Cl)cc1)c1cc2c(nc3sccn32)s1 nan
16007411 21859 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 3 2 3 4.4 CC(C)c1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1 nan
CHEMBL1320105 21859 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 3 2 3 4.4 CC(C)c1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1 nan
7692481 21897 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 3 3.4 COc1cc2cc(C(=O)N3CCc4ccccc4C3)[nH]c2cc1OC nan
CHEMBL1320436 21897 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 3 3.4 COc1cc2cc(C(=O)N3CCc4ccccc4C3)[nH]c2cc1OC nan
16019337 21967 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)cc1C nan
CHEMBL1321011 21967 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)cc1C nan
16017632 22010 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 3 2 6 5.0 Cc1c(C(=O)Nc2ccccc2)sc2nc(-c3cc4cc(Cl)ccc4oc3=O)[nH]c(=O)c12 nan
CHEMBL1321440 22010 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 3 2 6 5.0 Cc1c(C(=O)Nc2ccccc2)sc2nc(-c3cc4cc(Cl)ccc4oc3=O)[nH]c(=O)c12 nan
15988428 22012 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 1 0 5 3.6 Cn1c(=O)n(-c2cccc(Cl)c2)c(=O)c2sc3ccccc3c21 nan
CHEMBL1321495 22012 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 1 0 5 3.6 Cn1c(=O)n(-c2cccc(Cl)c2)c(=O)c2sc3ccccc3c21 nan
2988303 22014 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 6 3.2 Cn1c2ccc(F)cc2c2nnc(SCCN3CCCCC3)nc21 nan
CHEMBL1321509 22014 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 6 3.2 Cn1c2ccc(F)cc2c2nnc(SCCN3CCCCC3)nc21 nan
16017566 22045 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 2.9 Cc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
CHEMBL1321733 22045 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 2.9 Cc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
2158383 22198 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 6 1 6 2.1 CCOCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1323129 22198 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 6 1 6 2.1 CCOCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
6076700 22330 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 10 2 7 2.1 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2cccnc2)cc1 nan
CHEMBL1324242 22330 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 10 2 7 2.1 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2cccnc2)cc1 nan
16805712 22374 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 8 2 9 1.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)nnc12 nan
CHEMBL1324587 22374 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 8 2 9 1.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)nnc12 nan
3152453 22613 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 3 8 1.1 Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)c(=N)n(CCCO)c3nc12 nan
CHEMBL1326883 22613 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 3 8 1.1 Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)c(=N)n(CCCO)c3nc12 nan
5048043 22836 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1328648 22836 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
135706200 22859 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 3.2 CN(Cc1nc(O)c2ccccc2n1)C(=O)c1cccc(S(=O)(=O)N2CCCCCC2)c1 nan
CHEMBL1328897 22859 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 3.2 CN(Cc1nc(O)c2ccccc2n1)C(=O)c1cccc(S(=O)(=O)N2CCCCCC2)c1 nan
5730619 22884 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C\C(=O)c3ccncc3)cc2)c1C nan
CHEMBL1329130 22884 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C\C(=O)c3ccncc3)cc2)c1C nan
2937900 22919 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 5 4.3 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1ccccc1F)c1cccs1 nan
CHEMBL1329400 22919 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 5 4.3 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1ccccc1F)c1cccs1 nan
2765497 22933 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 2.4 Cc1ccc(S(=O)(=O)C(C)C(=O)NCCS(=O)(=O)c2ccc(Cl)cc2)cc1 nan
CHEMBL1329544 22933 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 2.4 Cc1ccc(S(=O)(=O)C(C)C(=O)NCCS(=O)(=O)c2ccc(Cl)cc2)cc1 nan
44142302 22936 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 2.8 CN(C)c1ccc(C#Cc2ccc3cc(CCO)oc(=O)c3c2)cc1 nan
CHEMBL1329575 22936 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 2.8 CN(C)c1ccc(C#Cc2ccc3cc(CCO)oc(=O)c3c2)cc1 nan
16011595 22989 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 9 1 7 4.7 CCCCOc1ccc(CNC(=O)C2CCCN(c3nnc(-n4c(C)ccc4C)s3)C2)cc1 nan
CHEMBL1330008 22989 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 9 1 7 4.7 CCCCOc1ccc(CNC(=O)C2CCCN(c3nnc(-n4c(C)ccc4C)s3)C2)cc1 nan
4181210 23013 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 3.9 Cc1ccc(NC(=O)CSc2nnc3ccc4ccccc4n23)cc1 nan
CHEMBL1330254 23013 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 3.9 Cc1ccc(NC(=O)CSc2nnc3ccc4ccccc4n23)cc1 nan
1548033 23015 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 3 3 7 -0.6 CN(C)C(=O)CNc1nnc(S)nc1O nan
CHEMBL1330266 23015 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 3 3 7 -0.6 CN(C)C(=O)CNc1nnc(S)nc1O nan
1960924 23107 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 4 6 2.4 COc1ccc(C(=O)NC(=S)Nc2ccc3[nH]c(O)nc3c2)c(OC)c1 nan
CHEMBL1330933 23107 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 4 6 2.4 COc1ccc(C(=O)NC(=S)Nc2ccc3[nH]c(O)nc3c2)c(OC)c1 nan
16022880 23177 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 2 7 4.3 COc1ccccc1NC(=O)Cn1c(=O)c(CNc2ccccc2)cc2cc(OC)c(OC)cc21 nan
CHEMBL1331405 23177 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 2 7 4.3 COc1ccccc1NC(=O)Cn1c(=O)c(CNc2ccccc2)cc2cc(OC)c(OC)cc21 nan
995088 23216 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 4 4.9 Cc1ccc(-c2cc(C(=O)NCc3cnn(C)c3C)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1331738 23216 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 4 4.9 Cc1ccc(-c2cc(C(=O)NCc3cnn(C)c3C)c3cc(Br)ccc3n2)cc1 nan
4975488 23399 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 0 8 1.8 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(C)CC4)o3)nnc2c2ccccc12 nan
CHEMBL1333127 23399 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 0 8 1.8 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(C)CC4)o3)nnc2c2ccccc12 nan
5219389 23458 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 1 7 2.9 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc3ccccc3oc2=O)c1 nan
CHEMBL1333624 23458 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 1 7 2.9 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc3ccccc3oc2=O)c1 nan
1298840 23468 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 7 5.1 CCn1c(SCC(=O)Nc2nc3ccccc3s2)nnc1-c1ccc(Br)cc1 nan
CHEMBL1333690 23468 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 7 5.1 CCn1c(SCC(=O)Nc2nc3ccccc3s2)nnc1-c1ccc(Br)cc1 nan
3586634 23489 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 5.2 CCCCn1c(SCC(=O)Nc2cccc(OC)c2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1333854 23489 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 5.2 CCCCn1c(SCC(=O)Nc2cccc(OC)c2)nc2c(sc3ccccc32)c1=O nan
1088584 23494 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 3 3.8 CC(=O)c1cn(CC(=O)Nc2ccc(C)cc2)c2ccccc12 nan
CHEMBL1333897 23494 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 3 3.8 CC(=O)c1cn(CC(=O)Nc2ccc(C)cc2)c2ccccc12 nan
1912959 23604 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 4 7 2.5 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
5728937 23604 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 4 7 2.5 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
5925428 23604 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 4 7 2.5 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
CHEMBL1334749 23604 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 4 7 2.5 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
5302178 23621 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
CHEMBL1334923 23621 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
15988344 23711 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 8 1 7 4.6 COc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccccc2Cl)cc1 nan
CHEMBL1335550 23711 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 8 1 7 4.6 COc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccccc2Cl)cc1 nan
3236871 23751 7 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 1 0 2 3.7 CCn1c(C)cc(=S)c2ccccc21 nan
CHEMBL1335833 23751 7 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 1 0 2 3.7 CCn1c(C)cc(=S)c2ccccc21 nan
3323389 23770 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 2 7 4.0 CC(=O)c1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)cc1 nan
CHEMBL1336041 23770 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 2 7 4.0 CC(=O)c1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)cc1 nan
135413771 23861 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 4.9 COc1cc(C2CC(c3c(C)cc(C)nc3O)=NN2c2ccccc2F)cc(OC)c1OC nan
CHEMBL1336821 23861 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 4.9 COc1cc(C2CC(c3c(C)cc(C)nc3O)=NN2c2ccccc2F)cc(OC)c1OC nan
2140203 23866 1 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 3 0 7 2.9 COc1ccc(-n2nnnc2-c2nc3ccccc3s2)cc1 nan
CHEMBL1336848 23866 1 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 3 0 7 2.9 COc1ccc(-n2nnnc2-c2nc3ccccc3s2)cc1 nan
2088251 23912 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 0 6 3.1 CCOc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1 nan
CHEMBL1337298 23912 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 0 6 3.1 CCOc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1 nan
1301366 23927 14 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 5 4.1 O=C(CCSc1nnc2ccc3ccccc3n12)Nc1ccc(F)cc1 nan
CHEMBL1337428 23927 14 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 5 4.1 O=C(CCSc1nnc2ccc3ccccc3n12)Nc1ccc(F)cc1 nan
16015123 23969 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 5 4.6 Cc1cccc(C)c1OCC(=O)Nc1nc(-c2ccc(Br)cc2)ns1 nan
CHEMBL1337810 23969 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 5 4.6 Cc1cccc(C)c1OCC(=O)Nc1nc(-c2ccc(Br)cc2)ns1 nan
16034823 23994 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 6 1 4 4.9 Cc1oc(-c2cccc(Br)c2)nc1CN1CCC(C(=O)NCc2ccccc2)CC1 nan
CHEMBL1338052 23994 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 6 1 4 4.9 Cc1oc(-c2cccc(Br)c2)nc1CN1CCC(C(=O)NCc2ccccc2)CC1 nan
2137854 24098 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
CHEMBL1338842 24098 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
16023227 24112 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 2 6 4.7 O=C(Cn1c(=O)c(CNc2ccccc2)cc2cc3c(cc21)OCCO3)Nc1ccccc1Cl nan
CHEMBL1339042 24112 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 2 6 4.7 O=C(Cn1c(=O)c(CNc2ccccc2)cc2cc3c(cc21)OCCO3)Nc1ccccc1Cl nan
4012037 24182 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 0 5 4.3 c1coc(CSc2ncnc3c2oc2ccccc23)c1 nan
CHEMBL1339672 24182 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 0 5 4.3 c1coc(CSc2ncnc3c2oc2ccccc23)c1 nan
16406923 24321 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 3 6 2.3 Cc1coc2c1c(C)cc1oc(=O)c(CC(=O)NCC(=O)N[C@H](C(=O)O)C(C)C)c(C)c12 nan
CHEMBL1340985 24321 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 3 6 2.3 Cc1coc2c1c(C)cc1oc(=O)c(CC(=O)NCC(=O)N[C@H](C(=O)O)C(C)C)c(C)c12 nan
1859832 24368 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 0 7 4.3 COc1ccc(CCn2c(-c3ccc(F)cc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1OC nan
CHEMBL1341311 24368 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 0 7 4.3 COc1ccc(CCn2c(-c3ccc(F)cc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1OC nan
6402475 24603 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 1 4 4.2 Nc1nc(-c2ccc(Cl)cc2)nnc1-c1ccc(Br)cc1 nan
CHEMBL1343242 24603 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 1 4 4.2 Nc1nc(-c2ccc(Cl)cc2)nnc1-c1ccc(Br)cc1 nan
1831284 24633 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 Cc1cc(C)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
4401304 24633 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 Cc1cc(C)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
CHEMBL1343474 24633 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 Cc1cc(C)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
3238813 24646 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 1 5 3.8 COc1ccc(-c2cc(C(=O)Nc3cccc(C(C)=O)c3)no2)cc1 nan
CHEMBL1343596 24646 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 1 5 3.8 COc1ccc(-c2cc(C(=O)Nc3cccc(C(C)=O)c3)no2)cc1 nan
2821813 24715 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 3 4.9 O=C(Nc1ccc(Cl)cc1Cl)c1ccc2ncsc2c1 nan
CHEMBL1344238 24715 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 3 4.9 O=C(Nc1ccc(Cl)cc1Cl)c1ccc2ncsc2c1 nan
3158796 24791 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 2 2 5 2.9 Cc1cccc(N2C(S)=C(C#N)C(=O)NC2c2ccco2)c1 nan
CHEMBL1344888 24791 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 2 2 5 2.9 Cc1cccc(N2C(S)=C(C#N)C(=O)NC2c2ccco2)c1 nan
2558333 24859 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 9 4.8 CCc1cc2c(SCc3nc(O)c4c(C)c(C(C)=O)sc4n3)ncnc2s1 nan
CHEMBL1345471 24859 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 9 4.8 CCc1cc2c(SCc3nc(O)c4c(C)c(C(C)=O)sc4n3)ncnc2s1 nan
7708092 24916 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 7 2.8 COc1ccc(C(=O)Nc2nnc(S(=O)(=O)Cc3ccccc3)s2)cc1 nan
CHEMBL1346001 24916 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 7 2.8 COc1ccc(C(=O)Nc2nnc(S(=O)(=O)Cc3ccccc3)s2)cc1 nan
4519571 25067 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 6 2.9 O=c1c2cc(Cl)ccc2nc(-c2ccc([N+](=O)[O-])cc2)n1O nan
CHEMBL1347185 25067 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 6 2.9 O=c1c2cc(Cl)ccc2nc(-c2ccc([N+](=O)[O-])cc2)n1O nan
24790251 25231 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 4 4.2 O=C(NCC1CCOCC1)c1ccc2nc(Cc3cccc(Cl)c3)oc2c1 nan
CHEMBL1348671 25231 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 4 4.2 O=C(NCC1CCOCC1)c1ccc2nc(Cc3cccc(Cl)c3)oc2c1 nan
16194270 25337 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 3.6 COc1cccc(CNC(=O)CSc2ccc(-c3cccs3)nn2)c1 nan
CHEMBL1349515 25337 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 3.6 COc1cccc(CNC(=O)CSc2ccc(-c3cccs3)nn2)c1 nan
2308471 25412 6 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 0 5 5.7 N#Cc1c(-c2ccc(F)cc2)cc(C2CC2)nc1SCC(=O)c1cccs1 nan
CHEMBL1350179 25412 6 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 0 5 5.7 N#Cc1c(-c2ccc(F)cc2)cc(C2CC2)nc1SCC(=O)c1cccs1 nan
1246228 25486 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 4.5 Cc1sc(NC(=O)c2oc3ccccc3c2C)c(C#N)c1C nan
CHEMBL1350806 25486 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 4.5 Cc1sc(NC(=O)c2oc3ccccc3c2C)c(C#N)c1C nan
3810755 25664 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(F)cc1)c1cc2ccccc2o1 nan
5224304 25664 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(F)cc1)c1cc2ccccc2o1 nan
CHEMBL1352306 25664 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(F)cc1)c1cc2ccccc2o1 nan
3710699 25776 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 3 0 5 3.2 CSc1nnc(-c2ccccc2SC)o1 nan
CHEMBL1353167 25776 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 3 0 5 3.2 CSc1nnc(-c2ccccc2SC)o1 nan
2408978 25871 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 4 3.8 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(Br)cc1 nan
CHEMBL1353794 25871 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 4 3.8 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(Br)cc1 nan
2137114 25961 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 5 4.4 Cc1ccc(C)c(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)c1 nan
CHEMBL1354500 25961 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 5 4.4 Cc1ccc(C)c(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)c1 nan
7177775 25990 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 4 0 7 1.8 Cc1ccc2nc(SCC(=O)N3CCN(c4ccccc4)CC3)nc(=O)n2c1 nan
CHEMBL1354880 25990 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 4 0 7 1.8 Cc1ccc2nc(SCC(=O)N3CCN(c4ccccc4)CC3)nc(=O)n2c1 nan
16015313 25994 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 5.8 COc1cccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4Cl)c3C)nc2C)c1 nan
CHEMBL1354922 25994 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 5.8 COc1cccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4Cl)c3C)nc2C)c1 nan
16019333 25995 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 4.8 CCc1ccc(Nc2nc3c(S(=O)(=O)c4ccc(C)cc4)nnn3c3ccsc23)cc1 nan
CHEMBL1354928 25995 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 4.8 CCc1ccc(Nc2nc3c(S(=O)(=O)c4ccc(C)cc4)nnn3c3ccsc23)cc1 nan
15988332 26025 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 0 9 2.1 CC(=O)c1ccc(N2CCN(C(=O)CCc3nnc4n(C)c(=O)c5sccc5n34)CC2)cc1 nan
CHEMBL1355272 26025 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 0 9 2.1 CC(=O)c1ccc(N2CCN(C(=O)CCc3nnc4n(C)c(=O)c5sccc5n34)CC2)cc1 nan
15988502 26058 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 4 4.5 O=C(Cn1c(=O)nc(-c2ccccc2)c2ccccc21)Nc1ccc(Cl)cc1F nan
CHEMBL1355773 26058 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 4 4.5 O=C(Cn1c(=O)nc(-c2ccccc2)c2ccccc21)Nc1ccc(Cl)cc1F nan
2893260 26163 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 9 4.0 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc1nnc(C(C)C)s1 nan
CHEMBL1357131 26163 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 9 4.0 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc1nnc(C(C)C)s1 nan
16018894 26171 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 0 7 5.8 CCc1nnc(SCc2nc(-c3ccccc3)oc2C)c2cc3sccc3n12 nan
CHEMBL1357169 26171 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 0 7 5.8 CCc1nnc(SCc2nc(-c3ccccc3)oc2C)c2cc3sccc3n12 nan
16012142 26207 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 5 5.0 CC(CNC(=O)Cn1ncc2c3ccccc3n(Cc3cccc(Cl)c3)c2c1=O)c1ccccc1 nan
CHEMBL1357797 26207 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 5 5.0 CC(CNC(=O)Cn1ncc2c3ccccc3n(Cc3cccc(Cl)c3)c2c1=O)c1ccccc1 nan
16018042 26225 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 5 3.2 CN(C)c1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
CHEMBL1358052 26225 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 5 3.2 CN(C)c1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
7711889 26285 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 6 0.2 Cn1c(CNS(=O)(=O)c2ccc(Cl)cc2)cc(=O)n(C)c1=O nan
CHEMBL1358800 26285 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 6 0.2 Cn1c(CNS(=O)(=O)c2ccc(Cl)cc2)cc(=O)n(C)c1=O nan
16018591 26348 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.7 COc1cc(NS(=O)(=O)c2cc3c(cc2C)N(C)CCO3)cc(OC)c1OC nan
CHEMBL1359260 26348 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.7 COc1cc(NS(=O)(=O)c2cc3c(cc2C)N(C)CCO3)cc(OC)c1OC nan
4302860 26359 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
4302861 26359 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1359331 26359 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
1270409 26369 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 11 -0.4 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC(C)(C)C)n2C)n(C)c1=O nan
CHEMBL1359403 26369 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 11 -0.4 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC(C)(C)C)n2C)n(C)c1=O nan
1472977 26437 16 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 0 3 5.3 Brc1cc(Br)c2nc(-c3ccc(N4CCOCC4)cc3)ccc2c1 nan
CHEMBL1360031 26437 16 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 0 3 5.3 Brc1cc(Br)c2nc(-c3ccc(N4CCOCC4)cc3)ccc2c1 nan
5910118 26472 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 7 3.3 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1360299 26472 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 7 3.3 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
2519123 26531 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 5 1 5 2.2 Cc1cccc(-c2nnc(SCC(=O)NC3CC3)n2C)c1 nan
CHEMBL1360828 26531 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 5 1 5 2.2 Cc1cccc(-c2nnc(SCC(=O)NC3CC3)n2C)c1 nan
1637639 26589 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 7 1 5 3.8 CC(=O)c1sc(NC(=O)CCCOc2ccccc2C)nc1C nan
CHEMBL1361423 26589 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 7 1 5 3.8 CC(=O)c1sc(NC(=O)CCCOc2ccccc2C)nc1C nan
16029936 26601 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.5 Cc1cc(C(=O)Nc2c(C)nc3ccccn3c2=O)ccc1[N+](=O)[O-] nan
CHEMBL1361527 26601 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.5 Cc1cc(C(=O)Nc2c(C)nc3ccccn3c2=O)ccc1[N+](=O)[O-] nan
16021826 26617 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cc(Cl)ccc2C)c(-c2ccccc2)n1 nan
CHEMBL1361623 26617 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cc(Cl)ccc2C)c(-c2ccccc2)n1 nan
135399263 26740 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 3.7 Cc1cccc(C)c1NC(=O)CSc1nc(O)c2ccccc2n1 nan
CHEMBL1362620 26740 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 3.7 Cc1cccc(C)c1NC(=O)CSc1nc(O)c2ccccc2n1 nan
5225696 26854 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 2 3 2.3 CC1=C(C#N)C(NC(=O)c2ccccc2Cl)(C(F)(F)F)C(=O)N1 nan
CHEMBL1363628 26854 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 2 3 2.3 CC1=C(C#N)C(NC(=O)c2ccccc2Cl)(C(F)(F)F)C(=O)N1 nan
1300378 26906 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 5 3.9 CC(=O)c1ccc(NC(=O)COc2ccccc2C(=O)Nc2ccc(C)cn2)cc1 nan
CHEMBL1364136 26906 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 5 3.9 CC(=O)c1ccc(NC(=O)COc2ccccc2C(=O)Nc2ccc(C)cn2)cc1 nan
1207158 26930 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 2 5 4.7 O=C(CSc1nc(-c2ccccc2)nc2ccccc12)Nc1cccc(C(=O)O)c1 nan
CHEMBL1364382 26930 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 2 5 4.7 O=C(CSc1nc(-c2ccccc2)nc2ccccc12)Nc1cccc(C(=O)O)c1 nan
658008 26932 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 6 1 5 3.7 CCN(CC)C(=O)CSC1=C(C#N)C(c2cccs2)C=C(C)N1 nan
CHEMBL1364397 26932 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 6 1 5 3.7 CCN(CC)C(=O)CSC1=C(C#N)C(c2cccs2)C=C(C)N1 nan
1071060 27152 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 2 6 3.1 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2OC)c1C nan
CHEMBL1366254 27152 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 2 6 3.1 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2OC)c1C nan
711643 27201 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 5 3.7 Cc1ccc(C(=O)Nc2nnc(COc3ccccc3)s2)cc1 nan
CHEMBL1366637 27201 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 5 3.7 Cc1ccc(C(=O)Nc2nnc(COc3ccccc3)s2)cc1 nan
16030455 27202 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 4 6.0 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)Nc1ccccc1C(F)(F)F nan
CHEMBL1366645 27202 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 4 6.0 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)Nc1ccccc1C(F)(F)F nan
16010113 27210 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 6 1 6 3.3 CC(C)Oc1ccc(CNC(=O)C2CCN(c3nc4ccccc4n(C)c3=O)CC2)cc1 nan
CHEMBL1366755 27210 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 6 1 6 3.3 CC(C)Oc1ccc(CNC(=O)C2CCN(c3nc4ccccc4n(C)c3=O)CC2)cc1 nan
2115552 27235 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 6 3.2 Cc1[nH]c2ccccc2c1C(=O)COC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 nan
CHEMBL1366975 27235 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 6 3.2 Cc1[nH]c2ccccc2c1C(=O)COC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 nan
868037 27336 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 4 3.4 COc1cccc2c(S)c(CCC(C)=O)c(C)nc12 nan
CHEMBL1367790 27336 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 4 3.4 COc1cccc2c(S)c(CCC(C)=O)c(C)nc12 nan
1086871 27473 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 8 1 8 3.4 COc1ccc(Cc2nnc(NC(=O)c3ccc(OC)c(OC)c3)s2)cc1OC nan
CHEMBL1368875 27473 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 8 1 8 3.4 COc1ccc(Cc2nnc(NC(=O)c3ccc(OC)c(OC)c3)s2)cc1OC nan
2054025 27760 10 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 7 4.0 COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1 nan
CHEMBL1370794 27760 10 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 7 4.0 COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1 nan
2951249 27822 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(OC)c(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)c1 nan
4590179 27822 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(OC)c(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1371319 27822 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(OC)c(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)c1 nan
1520515 27912 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 3 0 7 4.4 COc1ccc(-c2nc3ccccc3n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c23)cc1 nan
CHEMBL1372041 27912 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 3 0 7 4.4 COc1ccc(-c2nc3ccccc3n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c23)cc1 nan
15988500 27974 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 584 13 2 9 3.7 CCCCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)NCc3cccc(OC)c3OC)c2=O)CC1 nan
CHEMBL1372455 27974 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 584 13 2 9 3.7 CCCCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)NCc3cccc(OC)c3OC)c2=O)CC1 nan
16030415 28057 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 4.0 Cc1ccc2nc(COc3ccccc3NC(=O)c3ccccc3F)cc(=O)n2c1 nan
CHEMBL1372965 28057 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 4.0 Cc1ccc2nc(COc3ccccc3NC(=O)c3ccccc3F)cc(=O)n2c1 nan
3141921 28083 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 4 4.1 N#CCSc1nc(-c2ccccc2)nc2ccc(F)cc12 nan
CHEMBL1373143 28083 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 4 4.1 N#CCSc1nc(-c2ccccc2)nc2ccc(F)cc12 nan
5740603 28195 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 2 4 3.3 COc1ccc2[nH]c(/C(C#N)=C\c3ccc(C(=O)O)cc3)nc2c1 nan
CHEMBL1373830 28195 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 2 4 3.3 COc1ccc2[nH]c(/C(C#N)=C\c3ccc(C(=O)O)cc3)nc2c1 nan
4965542 28224 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 11 0.2 C=CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
CHEMBL1374122 28224 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 11 0.2 C=CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
3496625 28225 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 7 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(OCc3ccccc3)cc2)no1 nan
CHEMBL1374123 28225 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 7 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(OCc3ccccc3)cc2)no1 nan
2945949 28321 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 1 5 2.5 O=C(CCN1C(=O)c2cccc3cccc(c23)C1=O)Nc1ccon1 nan
CHEMBL1374764 28321 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 1 5 2.5 O=C(CCN1C(=O)c2cccc3cccc(c23)C1=O)Nc1ccon1 nan
15989514 28361 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 535 8 1 7 3.7 O=C(Cn1c(=O)n(CCCS(=O)(=O)C2CCCCC2)c(=O)c2ccccc21)Nc1ccc(F)c(Cl)c1 nan
CHEMBL1375013 28361 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 535 8 1 7 3.7 O=C(Cn1c(=O)n(CCCS(=O)(=O)C2CCCCC2)c(=O)c2ccccc21)Nc1ccc(F)c(Cl)c1 nan
2212703 28427 10 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 4 1 4 3.0 O=C(O)Cn1cc(C(=O)c2cccs2)c2ccccc21 nan
CHEMBL1375453 28427 10 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 4 1 4 3.0 O=C(O)Cn1cc(C(=O)c2cccs2)c2ccccc21 nan
2471579 28451 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 9 2 7 5.5 COc1ccc(-c2nc(NC(=O)c3ccc(OCC(=O)Nc4ccc(F)cc4)c(OC)c3)sc2C)cc1 nan
CHEMBL1375669 28451 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 9 2 7 5.5 COc1ccc(-c2nc(NC(=O)c3ccc(OCC(=O)Nc4ccc(F)cc4)c(OC)c3)sc2C)cc1 nan
3167528 28467 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 2 7 2.9 Cc1ccc(OCC(=O)NNC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 nan
CHEMBL1375776 28467 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 2 7 2.9 Cc1ccc(OCC(=O)NNC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 nan
2397772 28499 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 10 1.1 COc1cc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)ccc1OCCC(C)C nan
CHEMBL1376204 28499 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 10 1.1 COc1cc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)ccc1OCCC(C)C nan
1767629 28563 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 4 5.0 O=c1oc2c3c(ccc2c2ccccc12)OCN(Cc1ccccc1Cl)C3 nan
CHEMBL1376703 28563 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 4 5.0 O=c1oc2c3c(ccc2c2ccccc12)OCN(Cc1ccccc1Cl)C3 nan
16024679 28649 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 6 3.3 COc1cccc(C(=O)c2cn(CC(=O)NCc3ccccc3)c3nc(C)ccc3c2=O)c1 nan
CHEMBL1377672 28649 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 6 3.3 COc1cccc(C(=O)c2cn(CC(=O)NCc3ccccc3)c3nc(C)ccc3c2=O)c1 nan
135520779 28665 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 6 3.3 CCCc1nc2oc3c(O)ncnc3c2c2c1COC(C)(C)C2 nan
CHEMBL1377764 28665 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 6 3.3 CCCc1nc2oc3c(O)ncnc3c2c2c1COC(C)(C)C2 nan
16194561 28673 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)s1 nan
CHEMBL1377828 28673 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)s1 nan
16025409 28679 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 6 2.6 NC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1cccc(F)c1)S2(=O)=O nan
CHEMBL1377886 28679 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 6 2.6 NC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1cccc(F)c1)S2(=O)=O nan
2816168 28713 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 0 8 1.2 CCOC(=O)c1nnn2c1nc(N1CCN(C)CC1)c1ccccc12 nan
CHEMBL1378192 28713 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 0 8 1.2 CCOC(=O)c1nnn2c1nc(N1CCN(C)CC1)c1ccccc12 nan
16021577 28740 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 6 2.3 CCCNC(=O)C1CCN(c2ncnc3c2nc2n3CCCCC2)CC1 nan
CHEMBL1378416 28740 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 6 2.3 CCCNC(=O)C1CCN(c2ncnc3c2nc2n3CCCCC2)CC1 nan
20886481 28881 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 4 3.9 CC(C)Oc1ccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)cc1 nan
CHEMBL1379683 28881 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 4 3.9 CC(C)Oc1ccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)cc1 nan
2731492 28882 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 3 2 3 3.7 COc1cccc(NC(S)=Nc2cc(C)cc(C)n2)c1 nan
CHEMBL1379684 28882 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 3 2 3 3.7 COc1cccc(NC(S)=Nc2cc(C)cc(C)n2)c1 nan
614385 28928 83 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 225 1 2 4 2.7 Nc1ccc(-c2nc3cc(N)ccc3o2)cc1 nan
CHEMBL1380161 28928 83 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 225 1 2 4 2.7 Nc1ccc(-c2nc3cc(N)ccc3o2)cc1 nan
16187343 28967 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 0 7 4.1 CC(=O)c1ccc(-c2nnc(CCC(=O)N(C)Cc3cccc4cnccc34)o2)s1 nan
CHEMBL1380413 28967 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 0 7 4.1 CC(=O)c1ccc(-c2nnc(CCC(=O)N(C)Cc3cccc4cnccc34)o2)s1 nan
705209 28969 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 2 6 2.7 N#Cc1c(N)n(-c2ccc(C(=O)O)cc2)c2nc3ccccc3nc12 nan
CHEMBL1380440 28969 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 2 6 2.7 N#Cc1c(N)n(-c2ccc(C(=O)O)cc2)c2nc3ccccc3nc12 nan
3724835 28995 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 3.3 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
5033543 28995 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 3.3 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1380602 28995 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 3.3 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
1445317 28999 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 1 1 2 3.4 CCc1cc2ccc(C)cc2nc1S nan
CHEMBL1380640 28999 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 1 1 2 3.4 CCc1cc2ccc(C)cc2nc1S nan
4430260 29190 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 4 0 6 2.2 O=[N+]([O-])c1cccc(OCc2cn3cccnc3n2)c1 nan
CHEMBL1382302 29190 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 4 0 6 2.2 O=[N+]([O-])c1cccc(OCc2cn3cccnc3n2)c1 nan
3785801 29286 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 1 6 4.6 CCCCN(CCCC)C(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCCC3 nan
CHEMBL1383130 29286 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 1 6 4.6 CCCCN(CCCC)C(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCCC3 nan
3151314 29293 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 2 8 1.6 N=c1c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
CHEMBL1383245 29293 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 2 8 1.6 N=c1c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
16241852 29351 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.6 CCc1ccc(-n2c(=O)c3ccccc3n3c(S)nnc23)cc1.CN(C)C=O nan
CHEMBL1383752 29351 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.6 CCc1ccc(-n2c(=O)c3ccccc3n3c(S)nnc23)cc1.CN(C)C=O nan
9550688 29385 2 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 0 6 3.2 O=c1sc(N2CCN(c3ccc(F)cc3)CC2)nc2ccsc12 nan
CHEMBL1384034 29385 2 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 0 6 3.2 O=c1sc(N2CCN(c3ccc(F)cc3)CC2)nc2ccsc12 nan
23004552 29409 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 0 8 0.5 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3sccn3c2=O)CC1 nan
CHEMBL1384314 29409 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 0 8 0.5 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3sccn3c2=O)CC1 nan
1830897 29482 12 None -5 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 5 2.7 O=c1c(Cl)c(NS(=O)(=O)c2ccccc2)cnn1-c1ccccc1 nan
CHEMBL1384824 29482 12 None -5 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 5 2.7 O=c1c(Cl)c(NS(=O)(=O)c2ccccc2)cnn1-c1ccccc1 nan
2488909 29607 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 1 7 1.6 COC(=O)CNC(=O)CSc1nnc2cc(C)c3ccccc3n12 nan
CHEMBL1386026 29607 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 1 7 1.6 COC(=O)CNC(=O)CSc1nnc2cc(C)c3ccccc3n12 nan
1301168 29770 9 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 6 4.6 Cc1ccc(S(=O)(=O)c2nc(Nc3ccccc3C#N)sc2Cl)cc1 nan
CHEMBL1387246 29770 9 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 6 4.6 Cc1ccc(S(=O)(=O)c2nc(Nc3ccccc3C#N)sc2Cl)cc1 nan
6264256 29783 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 1 8 4.1 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)cc1OC nan
CHEMBL1387384 29783 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 1 8 4.1 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)cc1OC nan
20904611 29868 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 10 1 9 1.8 COCCCn1c(=O)c2sccc2n2c(CCCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1388050 29868 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 10 1 9 1.8 COCCCn1c(=O)c2sccc2n2c(CCCC(=O)NCC3CCCO3)nnc12 nan
2819135 29946 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 6 3.3 COc1cccc(-c2c(C#N)c(SC)nc3cc(C)nn23)c1 nan
CHEMBL1388609 29946 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 6 3.3 COc1cccc(-c2c(C#N)c(SC)nc3cc(C)nn23)c1 nan
900107 30029 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 2 1 6 -1.0 NC(=O)Cn1cnc2nc3n(c2c1=O)CCC3 nan
CHEMBL1389257 30029 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 2 1 6 -1.0 NC(=O)Cn1cnc2nc3n(c2c1=O)CCC3 nan
1934247 30056 7 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 527 9 2 6 5.3 COCCCNC(=O)c1c(NC(=O)c2ccccc2Cl)n(Cc2ccccc2)c2nc3ccccc3nc12 nan
CHEMBL1389486 30056 7 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 527 9 2 6 5.3 COCCCNC(=O)c1c(NC(=O)c2ccccc2Cl)n(Cc2ccccc2)c2nc3ccccc3nc12 nan
2012798 30146 9 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 7 4.4 Cc1ccc(Cn2c(N)c(S(=O)(=O)c3cccs3)c3nc4ccccc4nc32)cc1 nan
CHEMBL1390254 30146 9 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 7 4.4 Cc1ccc(Cn2c(N)c(S(=O)(=O)c3cccs3)c3nc4ccccc4nc32)cc1 nan
6290194 30256 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 1 7 3.3 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1391210 30256 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 1 7 3.3 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
16193052 30316 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 4 2.9 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccc(Br)cc1 nan
CHEMBL1391769 30316 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 4 2.9 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccc(Br)cc1 nan
886207 30472 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.3 CCNc1nc(C)c2cc(Br)c(=O)n(CC)c2n1 nan
CHEMBL1393118 30472 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.3 CCNc1nc(C)c2cc(Br)c(=O)n(CC)c2n1 nan
2889346 30487 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 1 4 3.5 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cn2)C1c1ccc(F)cc1 nan
CHEMBL1393200 30487 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 1 4 3.5 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cn2)C1c1ccc(F)cc1 nan
6622405 30491 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 0 6 2.9 CCn1c(=O)c2cc(C(=O)N(C)CC(OC)OC)sc2c2ccccc21 nan
CHEMBL1393223 30491 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 0 6 2.9 CCn1c(=O)c2cc(C(=O)N(C)CC(OC)OC)sc2c2ccccc21 nan
5181542 30519 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(Cl)cc2)no1 nan
CHEMBL1393467 30519 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(Cl)cc2)no1 nan
20917879 30526 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 0 6 2.4 CN(Cc1ccco1)S(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
CHEMBL1393505 30526 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 0 6 2.4 CN(Cc1ccco1)S(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
20888749 30559 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 8 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CC(C)OC(C)C2)s1 nan
CHEMBL1393784 30559 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 8 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CC(C)OC(C)C2)s1 nan
2135574 30629 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 9 1 8 4.4 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(OCC)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
CHEMBL1394559 30629 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 9 1 8 4.4 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(OCC)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
16033270 30630 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 5.3 Cc1ccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1394566 30630 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 5.3 Cc1ccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
16025819 30635 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 4 5.4 CCc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1394644 30635 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 4 5.4 CCc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
16018820 30643 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 7 1 8 4.7 CCc1nnc(SCC(=O)Nc2cc(Cl)c(OC)cc2OC)c2cc3oc(C)cc3n12 nan
CHEMBL1394778 30643 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 7 1 8 4.7 CCc1nnc(SCC(=O)Nc2cc(Cl)c(OC)cc2OC)c2cc3oc(C)cc3n12 nan
5144289 30666 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 4 3.4 O=C(NCCc1ccc(Cl)cc1)c1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1 nan
CHEMBL1394997 30666 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 4 3.4 O=C(NCCc1ccc(Cl)cc1)c1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1 nan
16031990 30680 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.7 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Br)cc3)nn2)s1 nan
CHEMBL1395113 30680 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.7 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Br)cc3)nn2)s1 nan
6200398 30699 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 7 2.8 CNc1oc(/C=C/c2cc(OC)c(OC)c(OC)c2)nc1C#N nan
CHEMBL1395288 30699 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 7 2.8 CNc1oc(/C=C/c2cc(OC)c(OC)c(OC)c2)nc1C#N nan
16033416 30708 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 5 5.8 CCOc1ccc(-c2cc(C(=O)NCc3ccc(OC)cc3)c3c(-c4ccc(F)cc4)[nH]nc3n2)cc1 nan
CHEMBL1395414 30708 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 5 5.8 CCOc1ccc(-c2cc(C(=O)NCc3ccc(OC)cc3)c3c(-c4ccc(F)cc4)[nH]nc3n2)cc1 nan
5323079 30734 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 4 5.2 CCOc1ccc(NC(=O)CSc2c3c(nc4ccccc24)CCCC3)cc1 nan
CHEMBL1395837 30734 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 4 5.2 CCOc1ccc(NC(=O)CSc2c3c(nc4ccccc24)CCCC3)cc1 nan
16024553 30737 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 5 4.2 Cc1ccc(CNC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)cc1 nan
CHEMBL1395881 30737 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 5 4.2 Cc1ccc(CNC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)cc1 nan
5296856 30759 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 4 2.6 Cc1cccn2c3c(c(=O)nc12)C(c1cccc(F)c1)CC(=O)N3 nan
CHEMBL1396255 30759 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 4 2.6 Cc1cccn2c3c(c(=O)nc12)C(c1cccc(F)c1)CC(=O)N3 nan
1730979 30762 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 1 3 6.9 O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1cc(-c2cccs2)nc2ccccc12 nan
CHEMBL1396294 30762 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 1 3 6.9 O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1cc(-c2cccs2)nc2ccccc12 nan
16019329 30766 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 4 0 9 2.6 CCN1CCN(c2nc3c(S(=O)(=O)c4ccc(C)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1396323 30766 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 4 0 9 2.6 CCN1CCN(c2nc3c(S(=O)(=O)c4ccc(C)cc4)nnn3c3ccsc23)CC1 nan
16018658 30777 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.9 CCc1cccc(C)c1NC(=O)C(CC)Sc1nncn2c1cc1occc12 nan
CHEMBL1396473 30777 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.9 CCc1cccc(C)c1NC(=O)C(CC)Sc1nncn2c1cc1occc12 nan
20885686 30843 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 1 6 1.4 Cc1nn(CCCC(=O)NCc2ccc(F)cc2)c(=O)c2nccn12 nan
CHEMBL1397376 30843 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 1 6 1.4 Cc1nn(CCCC(=O)NCc2ccc(F)cc2)c(=O)c2nccn12 nan
4904384 30861 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 1 3 3.5 COc1cc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2cc1OC nan
CHEMBL1397630 30861 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 1 3 3.5 COc1cc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2cc1OC nan
22517504 30912 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 2.3 Cc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N2CCCCC2)s1 nan
CHEMBL1398370 30912 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 2.3 Cc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N2CCCCC2)s1 nan
15989335 30927 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 13 2 7 4.4 CCOc1ccc(NC(=O)Cn2c(=O)n(CCCCC(=O)NCCc3ccc(Cl)cc3)c(=O)c3ccccc32)cc1 nan
CHEMBL1398481 30927 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 13 2 7 4.4 CCOc1ccc(NC(=O)Cn2c(=O)n(CCCCC(=O)NCCc3ccc(Cl)cc3)c(=O)c3ccccc32)cc1 nan
16022088 30936 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 4 0 6 4.8 COc1ccc2c(c1)c1c(c(=O)n(-c3cc(Cl)ccc3C)c(=O)n1Cc1ccc(F)cc1)n2C nan
CHEMBL1398563 30936 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 4 0 6 4.8 COc1ccc2c(c1)c1c(c(=O)n(-c3cc(Cl)ccc3C)c(=O)n1Cc1ccc(F)cc1)n2C nan
3594054 31031 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 5 6.2 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Br)c1 nan
CHEMBL1399458 31031 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 5 6.2 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Br)c1 nan
16017733 31044 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 5 2.8 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccccc1C(F)(F)F nan
CHEMBL1399598 31044 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 5 2.8 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccccc1C(F)(F)F nan
16023027 31154 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
CHEMBL1400601 31154 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
2992172 31295 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 5 1 7 2.8 CCOC(=O)c1sc(NC(=O)c2ccc(OC(C)=O)cc2)nc1C nan
CHEMBL1401867 31295 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 5 1 7 2.8 CCOC(=O)c1sc(NC(=O)c2ccc(OC(C)=O)cc2)nc1C nan
3124205 31349 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 4 3.3 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(F)cc2)cc1 nan
CHEMBL1402337 31349 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 4 3.3 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(F)cc2)cc1 nan
3833466 31390 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 1 8 4.3 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1402650 31390 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 1 8 4.3 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
1451311 31403 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 5 0 5 3.4 CCOC(=O)CSc1nc(C(C)C)nc2ccccc12 nan
CHEMBL1402735 31403 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 5 0 5 3.4 CCOC(=O)CSc1nc(C(C)C)nc2ccccc12 nan
698553 31429 35 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 4 3.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1 nan
CHEMBL1403001 31429 35 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 4 3.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1 nan
2679217 31479 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 1 5 3.5 COc1ccc2oc(C(=O)Nc3nccs3)c(C)c2c1 nan
CHEMBL1403552 31479 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 1 5 3.5 COc1ccc2oc(C(=O)Nc3nccs3)c(C)c2c1 nan
3705005 31567 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 0 0 1 4.2 Brc1cc(Br)c2nc3c(cc2c1)CCC3 nan
CHEMBL1404252 31567 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 0 0 1 4.2 Brc1cc(Br)c2nc3c(cc2c1)CCC3 nan
738260 31628 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 4.1 COc1cc2ccccc2cc1C(=O)Nc1ccc(Cl)cn1 nan
CHEMBL1404986 31628 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 4.1 COc1cc2ccccc2cc1C(=O)Nc1ccc(Cl)cn1 nan
16406961 31639 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 2 1 6 2.8 Cc1c(CC(=O)N2C[C@@H]3C[C@H](C2)Cn2c3cccc2=O)c(=O)oc2cc(O)c(Cl)cc12 nan
CHEMBL1405140 31639 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 2 1 6 2.8 Cc1c(CC(=O)N2C[C@@H]3C[C@H](C2)Cn2c3cccc2=O)c(=O)oc2cc(O)c(Cl)cc12 nan
1277429 31700 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 0 7 3.5 c1ccc(-c2cc3c(N4CCN(c5ncccn5)CC4)ncnc3s2)cc1 nan
CHEMBL1405710 31700 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 0 7 3.5 c1ccc(-c2cc3c(N4CCN(c5ncccn5)CC4)ncnc3s2)cc1 nan
135681062 31715 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 2 6 0.1 O=C(NCCCN1CCCC1=O)c1c(O)nc2ccccn2c1=O nan
CHEMBL1405883 31715 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 2 6 0.1 O=C(NCCCN1CCCC1=O)c1c(O)nc2ccccn2c1=O nan
2479912 31726 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 7 1.2 Cn1c(N)c(C(=O)COc2ccc(Cl)cc2Cl)c(=O)n(C)c1=O nan
CHEMBL1405949 31726 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 7 1.2 Cn1c(N)c(C(=O)COc2ccc(Cl)cc2Cl)c(=O)n(C)c1=O nan
665818 31889 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 5 2.2 CNc1ncnc2c3cc(OC)ccc3n(C)c12 nan
CHEMBL1407387 31889 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 5 2.2 CNc1ncnc2c3cc(OC)ccc3n(C)c12 nan
2956880 31894 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 4 2.7 O=C(Nc1ccc(N2CCOCC2)cc1)C1CC(=O)N(c2ccc(F)cc2)C1 nan
CHEMBL1407427 31894 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 4 2.7 O=C(Nc1ccc(N2CCOCC2)cc1)C1CC(=O)N(c2ccc(F)cc2)C1 nan
7080333 31941 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 4 3.9 Cc1c(-c2cccc(NC(=O)Cc3ccccc3)c2)nc2ncccn12 nan
CHEMBL1407681 31941 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 4 3.9 Cc1c(-c2cccc(NC(=O)Cc3ccccc3)c2)nc2ncccn12 nan
16016996 32046 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 3 0 6 2.4 Cc1ccc(Cl)cc1N1CCN(C(=O)C(C)n2ncn3cccc3c2=O)CC1 nan
CHEMBL1408470 32046 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 3 0 6 2.4 Cc1ccc(Cl)cc1N1CCN(C(=O)C(C)n2ncn3cccc3c2=O)CC1 nan
236431 32075 68 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 1 1 1 3.6 CC(=O)Nc1ccc(Br)c2ccccc12 nan
CHEMBL1408731 32075 68 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 1 1 1 3.6 CC(=O)Nc1ccc(Br)c2ccccc12 nan
16019396 32175 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 5 1 10 4.2 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NCc1ccc3c(c1)OCO3)c1sccc12 nan
CHEMBL1409519 32175 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 5 1 10 4.2 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NCc1ccc3c(c1)OCO3)c1sccc12 nan
6625357 32190 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 7 1 6 1.3 Cc1nn(CCCC(=O)NCCc2ccccc2)c(=O)c2nccn12 nan
CHEMBL1409636 32190 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 7 1 6 1.3 Cc1nn(CCCC(=O)NCCc2ccccc2)c(=O)c2nccn12 nan
302041 32543 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 7 1.9 Cn1c2ccccc2c2nnc(SCCN3CCOCC3)nc21 nan
CHEMBL1412491 32543 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 7 1.9 Cn1c2ccccc2c2nnc(SCCN3CCOCC3)nc21 nan
2100500 32555 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 1 3 4.1 Cc1c(Cl)cccc1NC(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O nan
CHEMBL1412600 32555 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 1 3 4.1 Cc1c(Cl)cccc1NC(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O nan
2059848 32680 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 2 8 3.2 Cc1cc(C)nc(SCC(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)n1 nan
CHEMBL1413582 32680 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 2 8 3.2 Cc1cc(C)nc(SCC(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)n1 nan
16017166 32739 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 6 4.0 COc1cccc(CNC(=O)CCCn2nc(C)c3sc4ccccc4c3c2=O)c1 nan
CHEMBL1414014 32739 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 6 4.0 COc1cccc(CNC(=O)CCCn2nc(C)c3sc4ccccc4c3c2=O)c1 nan
2919306 32769 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 5 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(C)o2)C1c1cccc(Br)c1 nan
CHEMBL1414306 32769 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 5 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(C)o2)C1c1cccc(Br)c1 nan
16015068 32776 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 4 4.8 Cc1c(Cl)cccc1NC(=O)CSc1cc(-c2ccccc2)ncn1 nan
CHEMBL1414379 32776 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 4 4.8 Cc1c(Cl)cccc1NC(=O)CSc1cc(-c2ccccc2)ncn1 nan
16010393 32787 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 2 0 3 5.9 Cc1cccc2c1-c1sc(C(=O)N(C)c3cccc(C(F)(F)F)c3)cc1CO2 nan
CHEMBL1414451 32787 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 2 0 3 5.9 Cc1cccc2c1-c1sc(C(=O)N(C)c3cccc(C(F)(F)F)c3)cc1CO2 nan
3245690 33107 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 2 1 7 4.2 Cc1nc2ccc3nc(NC(=O)c4ccc5c(c4)OCCO5)sc3c2s1 nan
CHEMBL1417231 33107 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 2 1 7 4.2 Cc1nc2ccc3nc(NC(=O)c4ccc5c(c4)OCCO5)sc3c2s1 nan
24792497 33192 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 8 2.5 COc1ccc2cc(C#N)c(SCC(=O)Nc3nonc3C)nc2c1 nan
CHEMBL1417975 33192 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 8 2.5 COc1ccc2cc(C#N)c(SCC(=O)Nc3nonc3C)nc2c1 nan
2473907 33351 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 3.1 CCOC(=O)c1cc(-c2ccc(F)cc2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 nan
CHEMBL1419339 33351 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 3.1 CCOC(=O)c1cc(-c2ccc(F)cc2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 nan
2980984 33443 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 1 6 4.3 CC1(C)Cc2c(sc3c2c(N)nc(=S)n3Cc2ccccc2)CO1 nan
CHEMBL1420144 33443 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 1 6 4.3 CC1(C)Cc2c(sc3c2c(N)nc(=S)n3Cc2ccccc2)CO1 nan
16745931 33590 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 3 2 6 3.9 Cc1ccc(-c2csc3nc4cc(C(=O)NC5CCC(O)CC5)ccc4c(=O)n23)cc1 nan
CHEMBL1421354 33590 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 3 2 6 3.9 Cc1ccc(-c2csc3nc4cc(C(=O)NC5CCC(O)CC5)ccc4c(=O)n23)cc1 nan
2138543 33668 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
CHEMBL1422079 33668 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
6045016 33829 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 9 1 7 4.3 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1423355 33829 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 9 1 7 4.3 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
3725185 33866 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 4 5.2 CN(C)c1ccc(P(=O)(OCc2ccccc2)C(O)c2ccc(Cl)cc2)cc1 nan
CHEMBL1423606 33866 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 4 5.2 CN(C)c1ccc(P(=O)(OCc2ccccc2)C(O)c2ccc(Cl)cc2)cc1 nan
135420429 33870 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 2 9 3.4 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1nnc(C)s1 nan
CHEMBL1423657 33870 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 2 9 3.4 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1nnc(C)s1 nan
950417 34016 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 0 7 1.2 Cc1cccn2c(=O)c(C=C(C#N)C#N)c(N3CCN(C)CC3)nc12 nan
CHEMBL1424893 34016 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 0 7 1.2 Cc1cccn2c(=O)c(C=C(C#N)C#N)c(N3CCN(C)CC3)nc12 nan
4008202 34337 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 9 1.9 CCOC(=O)c1sc2nc(C)nc(SCC(=O)NC3CCS(=O)(=O)C3)c2c1C nan
CHEMBL1427679 34337 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 9 1.9 CCOC(=O)c1sc2nc(C)nc(SCC(=O)NC3CCS(=O)(=O)C3)c2c1C nan
2810151 34365 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 1 4 3.7 O=C(Nc1nc2ccccc2c(=O)s1)c1ccc(F)cc1Cl nan
CHEMBL1427961 34365 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 1 4 3.7 O=C(Nc1nc2ccccc2c(=O)s1)c1ccc(F)cc1Cl nan
4603734 34560 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 7 2.3 O=C(COc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1Cl nan
CHEMBL1429555 34560 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 7 2.3 O=C(COc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1Cl nan
2369101 34567 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 5 3.2 CCN1C(=O)C(=C2C=C(C)N(Cc3ccco3)C(C)=C2)C(=O)N(CC)C1=S nan
CHEMBL1429586 34567 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 5 3.2 CCN1C(=O)C(=C2C=C(C)N(Cc3ccco3)C(C)=C2)C(=O)N(CC)C1=S nan
6110891 34577 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 3.4 O=C(C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1429670 34577 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 3.4 O=C(C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 nan
3186593 34800 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 8 0.3 CC1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
CHEMBL1431426 34800 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 8 0.3 CC1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
4836291 34900 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 3 4.9 CCC1CCCCN1C(=O)COc1c(Br)cc(Br)c2cccnc12 nan
CHEMBL1432322 34900 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 3 4.9 CCC1CCCCN1C(=O)COc1c(Br)cc(Br)c2cccnc12 nan
3236746 34917 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 7 2 4 3.9 CCOc1ccc(OCC)c(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 nan
CHEMBL1432463 34917 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 7 2 4 3.9 CCOc1ccc(OCC)c(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 nan
5186080 35002 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 3 0 5 3.1 CC1(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)CC1(Cl)Cl nan
CHEMBL1433143 35002 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 3 0 5 3.1 CC1(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)CC1(Cl)Cl nan
16025762 35041 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)C1 nan
CHEMBL1433427 35041 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)C1 nan
16031695 35111 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 5 2.7 CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)cc1 nan
CHEMBL1434575 35111 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 5 2.7 CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)cc1 nan
1003863 35128 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 2 5 5.6 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(Cl)cc4F)sc3n2)c1 nan
CHEMBL1434727 35128 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 2 5 5.6 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(Cl)cc4F)sc3n2)c1 nan
16404473 35159 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 545 8 1 8 3.7 COc1cc(OC)c(OC)cc1/C=C1\Oc2cc(OCC(=O)N3Cc4ccccc4C[C@H]3C(=O)O)ccc2C1=O nan
CHEMBL1435093 35159 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 545 8 1 8 3.7 COc1cc(OC)c(OC)cc1/C=C1\Oc2cc(OCC(=O)N3Cc4ccccc4C[C@H]3C(=O)O)ccc2C1=O nan
24891925 35178 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 7 2.3 O=C(CSc1nnc2ccc(-c3ccc(F)cc3)nn12)NCC1CCCO1 nan
CHEMBL1435281 35178 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 7 2.3 O=C(CSc1nnc2ccc(-c3ccc(F)cc3)nn12)NCC1CCCO1 nan
16416480 35182 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 6 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1 nan
5457481 35182 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 6 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1 nan
CHEMBL1435346 35182 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 6 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1 nan
16034509 35186 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 6 4.6 CN(C)c1ccc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
CHEMBL1435377 35186 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 6 4.6 CN(C)c1ccc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
15989215 35199 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 8 2.8 COc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(OC)c(OC)c3)c(=O)c3ccccc32)cc1 nan
CHEMBL1435575 35199 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 8 2.8 COc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(OC)c(OC)c3)c(=O)c3ccccc32)cc1 nan
4281326 35257 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 4 5.3 Cc1cccc(C)c1OCC(=O)Nc1c(C(=O)c2ccccc2)oc2ccccc12 nan
CHEMBL1436278 35257 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 4 5.3 Cc1cccc(C)c1OCC(=O)Nc1c(C(=O)c2ccccc2)oc2ccccc12 nan
16009492 35349 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3cccc(NC(=O)c4ccccc4F)c3)cc(=O)n12 nan
CHEMBL1437588 35349 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3cccc(NC(=O)c4ccccc4F)c3)cc(=O)n12 nan
16015683 35351 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 1 5 5.9 O=C(Nc1ccc2nc(SCC(=O)N3CCc4ccccc43)sc2c1)c1ccc(Cl)cc1 nan
CHEMBL1437631 35351 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 1 5 5.9 O=C(Nc1ccc2nc(SCC(=O)N3CCc4ccccc43)sc2c1)c1ccc(Cl)cc1 nan
16025792 35363 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 5 4.9 COc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1437725 35363 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 5 4.9 COc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
4523316 35468 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 0 5 2.6 CN(C(=O)c1cc2c(=O)n3ccccc3nc2n1C)C1CCCCC1 nan
CHEMBL1438580 35468 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 0 5 2.6 CN(C(=O)c1cc2c(=O)n3ccccc3nc2n1C)C1CCCCC1 nan
16012068 35527 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 2.6 Cc1cc(=O)n2nc(N3CCC(C(=O)NCc4ccc(Cl)cc4)CC3)sc2n1 nan
CHEMBL1439177 35527 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 2.6 Cc1cc(=O)n2nc(N3CCC(C(=O)NCc4ccc(Cl)cc4)CC3)sc2n1 nan
3846910 35548 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 2 6 4.2 Cc1ccccc1NC(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCCC3 nan
CHEMBL1439341 35548 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 2 6 4.2 Cc1ccccc1NC(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCCC3 nan
4246549 35711 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 1 4 5.2 Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCCCCC4)cc3c2C)c(C)c1 nan
CHEMBL1440777 35711 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 1 4 5.2 Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCCCCC4)cc3c2C)c(C)c1 nan
4230097 35730 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 9 1 9 4.1 O=C(O)CCCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
CHEMBL1440951 35730 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 9 1 9 4.1 O=C(O)CCCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
3272255 35864 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 2 7 0.7 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCC(C(N)=O)CC3)c(=O)c2c1C nan
CHEMBL1442168 35864 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 2 7 0.7 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCC(C(N)=O)CC3)c(=O)c2c1C nan
1077468 35893 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 2 8 1.8 Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CCCN4CCOCC4)c3nc12 nan
CHEMBL1442429 35893 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 2 8 1.8 Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CCCN4CCOCC4)c3nc12 nan
20876076 35907 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 0.8 COc1ccc(C)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1442544 35907 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 0.8 COc1ccc(C)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
7217841 35952 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 6 2.9 Cc1nnc2ccc(-c3ccc(NC(=O)c4ccco4)cc3)nn12 nan
CHEMBL1442956 35952 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 6 2.9 Cc1nnc2ccc(-c3ccc(NC(=O)c4ccco4)cc3)nn12 nan
2975734 35961 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 0 7 2.3 CCOC(=O)C1CCCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)C1 nan
CHEMBL1443010 35961 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 0 7 2.3 CCOC(=O)C1CCCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)C1 nan
4611621 36117 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 6 4.8 COc1ccc(C2=NN(c3ccc(C(=O)O)cc3)C(c3ccc(OC)c(OC)c3)C2)cc1 nan
CHEMBL1444507 36117 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 6 4.8 COc1ccc(C2=NN(c3ccc(C(=O)O)cc3)C(c3ccc(OC)c(OC)c3)C2)cc1 nan
817359 36134 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 3 3.6 CC(=O)c1ccc(NC(=S)NC(=O)Cc2ccc(Cl)cc2)cc1 nan
CHEMBL1444699 36134 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 3 3.6 CC(=O)c1ccc(NC(=S)NC(=O)Cc2ccc(Cl)cc2)cc1 nan
4051948 36137 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 5 4.6 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccc(Cl)c2)o1 nan
CHEMBL1444743 36137 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 5 4.6 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccc(Cl)c2)o1 nan
3186591 36174 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 8 0.5 CC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1445043 36174 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 8 0.5 CC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
16187836 36268 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 1 10 1.1 COc1ccccc1-c1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1445914 36268 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 1 10 1.1 COc1ccccc1-c1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
16017757 36384 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 5 2.9 CCc1ccc(NC(=O)Cn2ccn(-c3cccc(Cl)c3)c(=O)c2=O)cc1 nan
CHEMBL1446963 36384 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 5 2.9 CCc1ccc(NC(=O)Cn2ccn(-c3cccc(Cl)c3)c(=O)c2=O)cc1 nan
2769301 36541 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 4 3.7 COc1ccc(-c2cc(C(=O)Nc3ccccc3F)on2)cc1 nan
CHEMBL1448341 36541 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 4 3.7 COc1ccc(-c2cc(C(=O)Nc3ccccc3F)on2)cc1 nan
3658309 36695 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 548 11 1 8 4.8 COc1cc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
CHEMBL1449439 36695 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 548 11 1 8 4.8 COc1cc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
3652194 36760 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 1 0 2 5.5 Brc1cc(Br)c2nc(-c3cccs3)ccc2c1 nan
CHEMBL1449966 36760 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 1 0 2 5.5 Brc1cc(Br)c2nc(-c3cccs3)ccc2c1 nan
3244704 36868 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 2 7 3.3 COc1ccc(C2C=C(c3cccs3)Nc3nc(CCCO)nn32)cc1 nan
CHEMBL1450888 36868 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 2 7 3.3 COc1ccc(C2C=C(c3cccs3)Nc3nc(CCCO)nn32)cc1 nan
1774540 37045 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 4 5.0 O=c1oc2c3c(ccc2c2ccccc12)OCN(Cc1cccc(Cl)c1)C3 nan
CHEMBL1452222 37045 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 4 5.0 O=c1oc2c3c(ccc2c2ccccc12)OCN(Cc1cccc(Cl)c1)C3 nan
649434 37133 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 7 4.2 CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
CHEMBL1452945 37133 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 7 4.2 CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
16187616 37283 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 10 2.8 COc1ccc(-c2nnc3ccc(SCC(=O)Nc4cc(C)on4)nn23)cc1OC nan
CHEMBL1454124 37283 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 10 2.8 COc1ccc(-c2nnc3ccc(SCC(=O)Nc4cc(C)on4)nn23)cc1OC nan
17580690 37320 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 1 1 2 3.5 Cc1c(C(=O)N2CC(C)OC(C)C2)[nH]c2ccc(Br)cc12 nan
CHEMBL1454451 37320 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 1 1 2 3.5 Cc1c(C(=O)N2CC(C)OC(C)C2)[nH]c2ccc(Br)cc12 nan
18204435 37415 5 None -48 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 4 2 6 3.5 CNC(=O)c1ccc(NC(=O)C2CCN(c3ncnc4sc(C)c(C)c34)CC2)cc1 nan
CHEMBL1455259 37415 5 None -48 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 4 2 6 3.5 CNC(=O)c1ccc(NC(=O)C2CCN(c3ncnc4sc(C)c(C)c34)CC2)cc1 nan
1265180 37522 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 8 1.0 CCCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1456231 37522 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 8 1.0 CCCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
24793479 37640 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 6 3.3 COc1ccc(C(=O)NNC(=O)CSc2nc(C(C)C)nc3ccccc23)cc1 nan
CHEMBL1457367 37640 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 6 3.3 COc1ccc(C(=O)NNC(=O)CSc2nc(C(C)C)nc3ccccc23)cc1 nan
24819691 37732 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 3 4 3.2 COc1ccc2cc(OCC(=O)NNC(=O)Nc3ccc(F)cc3)ccc2c1 nan
CHEMBL1458070 37732 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 3 4 3.2 COc1ccc2cc(OCC(=O)NNC(=O)Nc3ccc(F)cc3)ccc2c1 nan
675984 37837 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 0 2 4.0 O=C(COc1ccc2ccccc2c1Br)N1CCCCC1 nan
CHEMBL1458979 37837 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 0 2 4.0 O=C(COc1ccc2ccccc2c1Br)N1CCCCC1 nan
866601 37969 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 5 3.4 O=C(NC1CCCCCC1)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1460115 37969 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 5 3.4 O=C(NC1CCCCCC1)c1cc2c(=O)n3ccccc3nc2s1 nan
20912606 38158 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 0 7 3.4 CN(C)CCN(Cc1ccccc1)C(=O)C1CCN(c2ncnc3c2nc2n3CCCCC2)CC1 nan
CHEMBL1461808 38158 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 0 7 3.4 CN(C)CCN(Cc1ccccc1)C(=O)C1CCN(c2ncnc3c2nc2n3CCCCC2)CC1 nan
2745719 38383 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 1 5 2.8 CC(=O)Nc1nccc(-c2cc(-c3ccccc3)no2)n1 nan
CHEMBL1463690 38383 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 1 5 2.8 CC(=O)Nc1nccc(-c2cc(-c3ccccc3)no2)n1 nan
741378 38539 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 3.4 COC(=O)Sc1nnc(-c2ccc(Br)cc2)o1 nan
CHEMBL1464821 38539 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 3.4 COC(=O)Sc1nnc(-c2ccc(Br)cc2)o1 nan
203396 38570 88 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 1 0 3 2.8 O=c1c(Br)c(Br)cnn1-c1ccccc1 nan
CHEMBL1465040 38570 88 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 1 0 3 2.8 O=c1c(Br)c(Br)cnn1-c1ccccc1 nan
3518230 38590 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 4.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(Cl)cc1)c1cc2ccccc2o1 nan
4024784 38590 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 4.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(Cl)cc1)c1cc2ccccc2o1 nan
CHEMBL1465171 38590 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 4.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(Cl)cc1)c1cc2ccccc2o1 nan
24791767 38642 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 0 6 3.5 CCN(Cc1cnn(C)c1)C(=O)c1cc(COc2ccc3c(c2)CCCC3)on1 nan
CHEMBL1465549 38642 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 0 6 3.5 CCN(Cc1cnn(C)c1)C(=O)c1cc(COc2ccc3c(c2)CCCC3)on1 nan
16241464 38855 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 0 8 2.7 CN(C)C=O.O=[N+]([O-])c1cccc(COc2ncnc3cc([N+](=O)[O-])ccc23)c1 nan
CHEMBL1467247 38855 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 0 8 2.7 CN(C)C=O.O=[N+]([O-])c1cccc(COc2ncnc3cc([N+](=O)[O-])ccc23)c1 nan
1244301 38954 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 2 3.8 Cc1c(C(=O)NCc2ccccc2F)oc2ccccc12 nan
CHEMBL1468217 38954 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 2 3.8 Cc1c(C(=O)NCc2ccccc2F)oc2ccccc12 nan
18561646 39002 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 9 0.6 CC(C)Cc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1468525 39002 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 9 0.6 CC(C)Cc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
4257704 39060 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 1 7 3.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)c1 nan
CHEMBL1468952 39060 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 1 7 3.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)c1 nan
20957237 39196 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 9 1.7 COc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1470126 39196 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 9 1.7 COc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
1261892 39199 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 2 5 3.7 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(-c3ccccn3)nc3ccc(Br)cc23)cc1 nan
CHEMBL1470208 39199 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 2 5 3.7 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(-c3ccccn3)nc3ccc(Br)cc23)cc1 nan
2725142 39311 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 7 2.4 COc1nc(N)c(C#N)c(-c2ccc(N(C)CCC#N)cc2)c1C#N nan
CHEMBL1471123 39311 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 7 2.4 COc1nc(N)c(C#N)c(-c2ccc(N(C)CCC#N)cc2)c1C#N nan
15988569 39496 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 6 5.5 Cc1ccc(-c2nc(-c3cc4cccc(OCc5ccc(F)cc5)c4oc3=O)no2)cc1 nan
CHEMBL1472849 39496 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 6 5.5 Cc1ccc(-c2nc(-c3cc4cccc(OCc5ccc(F)cc5)c4oc3=O)no2)cc1 nan
1166244 39507 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 5.6 Cc1cccc(C)c1NC(=O)CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)n1 nan
CHEMBL1472996 39507 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 5.6 Cc1cccc(C)c1NC(=O)CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)n1 nan
16025417 39525 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 8 1 7 5.3 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2ccccc2C)S3(=O)=O)cc1 nan
CHEMBL1473284 39525 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 8 1 7 5.3 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2ccccc2C)S3(=O)=O)cc1 nan
16009695 39591 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 4 1 6 4.5 O=C(Cn1c(=O)n(-c2ccccc2Cl)c(=O)c2sc3ccccc3c21)NC1CCCCC1 nan
CHEMBL1474245 39591 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 4 1 6 4.5 O=C(Cn1c(=O)n(-c2ccccc2Cl)c(=O)c2sc3ccccc3c21)NC1CCCCC1 nan
2158398 39597 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 1 6 3.8 COc1ccc(Cl)cc1NC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1474329 39597 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 1 6 3.8 COc1ccc(Cl)cc1NC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
16009720 39602 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 4.9 COc1ccc(CNc2nc3c(-c4ccc(C)cc4)nnn3c3ccccc23)cc1 nan
CHEMBL1474419 39602 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 4.9 COc1ccc(CNc2nc3c(-c4ccc(C)cc4)nnn3c3ccccc23)cc1 nan
16016110 39640 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 1 7 4.8 Cc1ccc(CNc2ccc(-c3nc(-c4ccco4)no3)cc2[N+](=O)[O-])cc1 nan
CHEMBL1474896 39640 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 1 7 4.8 Cc1ccc(CNc2ccc(-c3nc(-c4ccco4)no3)cc2[N+](=O)[O-])cc1 nan
16033296 39642 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccccc1CNC(=O)c1sc2ncnc(N(C)C3CCCCC3)c2c1C nan
CHEMBL1474937 39642 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccccc1CNC(=O)c1sc2ncnc(N(C)C3CCCCC3)c2c1C nan
3155029 39693 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 5 2.1 COc1ccc(CCNC(=O)CN2C(=O)COc3ccc(C)cc32)cc1OC nan
CHEMBL1475587 39693 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 5 2.1 COc1ccc(CCNC(=O)CN2C(=O)COc3ccc(C)cc32)cc1OC nan
16020275 39696 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 9 2 7 4.6 CCc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(OC)cc3)c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc32)cc1 nan
CHEMBL1475630 39696 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 9 2 7 4.6 CCc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(OC)cc3)c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc32)cc1 nan
16415433 39698 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1OC nan
5513689 39698 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1OC nan
CHEMBL1475648 39698 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1OC nan
3646895 39716 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 9 1 7 4.9 CCOCCCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1475830 39716 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 9 1 7 4.9 CCOCCCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
16020214 39720 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 644 7 2 8 4.4 O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2ccc(C(=O)NCc3ccc4c(c3)OCO4)cc21)Nc1ccc(Br)cc1F nan
CHEMBL1475923 39720 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 644 7 2 8 4.4 O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2ccc(C(=O)NCc3ccc4c(c3)OCO4)cc21)Nc1ccc(Br)cc1F nan
15990518 39733 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 4.9 CCOC(=O)c1cccc(NC(=O)c2cc3cc4cc(OC)ccc4nc3s2)c1 nan
CHEMBL1476197 39733 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 4.9 CCOC(=O)c1cccc(NC(=O)c2cc3cc4cc(OC)ccc4nc3s2)c1 nan
16018050 39773 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 COc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1OC nan
CHEMBL1476725 39773 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 COc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1OC nan
18572231 39797 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 8 2.6 CCOc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
CHEMBL1477019 39797 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 8 2.6 CCOc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
5294687 39829 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 8 2 4 5.3 CCCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1477360 39829 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 8 2 4 5.3 CCCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
3096467 39901 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 8 0 5 4.2 CCn1c(/C=C/N(C(C)=O)c2ccccc2)[n+](CCCS(=O)(=O)[O-])c2cc(Cl)c(Cl)cc21 nan
5751261 39901 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 8 0 5 4.2 CCn1c(/C=C/N(C(C)=O)c2ccccc2)[n+](CCCS(=O)(=O)[O-])c2cc(Cl)c(Cl)cc21 nan
CHEMBL1477993 39901 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 8 0 5 4.2 CCn1c(/C=C/N(C(C)=O)c2ccccc2)[n+](CCCS(=O)(=O)[O-])c2cc(Cl)c(Cl)cc21 nan
2027019 39968 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 7 5.3 CSc1nc(SCC(=O)O)c2sc3nc(-c4ccccc4)c4c(c3c2n1)CCC4 nan
CHEMBL1478587 39968 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 7 5.3 CSc1nc(SCC(=O)O)c2sc3nc(-c4ccccc4)c4c(c3c2n1)CCC4 nan
2487220 40083 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 3.8 CCn1cc(C(=O)OCC(=O)Nc2cccc(Cl)c2Cl)c(=O)c2ccc(C)nc21 nan
CHEMBL1479594 40083 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 3.8 CCn1cc(C(=O)OCC(=O)Nc2cccc(Cl)c2Cl)c(=O)c2ccc(C)nc21 nan
16024523 40144 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 5 3.6 Cc1ccc(C(=O)c2cn(CC(=O)NCc3ccccc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1480079 40144 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 5 3.6 Cc1ccc(C(=O)c2cn(CC(=O)NCc3ccccc3)c3nc(C)ccc3c2=O)cc1 nan
16019201 40158 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 7 4.2 COc1ccc(Cn2c(=O)c3oc4ccccc4c3n(CC(=O)Nc3cc(C)cc(C)c3)c2=O)cc1 nan
CHEMBL1480191 40158 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 7 4.2 COc1ccc(Cn2c(=O)c3oc4ccccc4c3n(CC(=O)Nc3cc(C)cc(C)c3)c2=O)cc1 nan
5925055 40353 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Cl)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1481881 40353 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Cl)c1)c1ccc2c(c1)OCCO2 nan
7258994 40361 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 8 1.9 Cc1ccc2nc(SCC(=O)Nc3ccc4c(c3)OCCO4)nc(=O)n2c1 nan
CHEMBL1481935 40361 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 8 1.9 Cc1ccc2nc(SCC(=O)Nc3ccc4c(c3)OCCO4)nc(=O)n2c1 nan
1470918 40443 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 4 3.7 Cc1ccccc1C(=O)NN(C)c1nc2ccccc2nc1C(F)(F)F nan
CHEMBL1482653 40443 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 4 3.7 Cc1ccccc1C(=O)NN(C)c1nc2ccccc2nc1C(F)(F)F nan
3122172 40487 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 3 4.6 CC(=O)C1=C(O)C(=O)N(c2cccc(Br)c2)C1c1ccccc1Cl nan
CHEMBL1483069 40487 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 3 4.6 CC(=O)C1=C(O)C(=O)N(c2cccc(Br)c2)C1c1ccccc1Cl nan
1093408 40537 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 2 5 4.3 COCc1cc(C)nc2sc(C(=O)Nc3ccccc3Br)c(N)c12 nan
CHEMBL1483523 40537 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 2 5 4.3 COCc1cc(C)nc2sc(C(=O)Nc3ccccc3Br)c(N)c12 nan
1868051 40569 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 7 3.4 CSc1nc(SCC(=O)O)c2c3c(sc2n1)COC(C)(C)C3 nan
CHEMBL1483727 40569 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 7 3.4 CSc1nc(SCC(=O)O)c2c3c(sc2n1)COC(C)(C)C3 nan
4968512 40668 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 209 1 2 5 2.1 Nc1ccccc1-c1nnc(S)s1 nan
CHEMBL1484500 40668 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 209 1 2 5 2.1 Nc1ccccc1-c1nnc(S)s1 nan
1130974 40703 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 2 6 3.5 CCOc1ccc(NC(=O)c2sc(NC(C)=O)c(C(=O)OC)c2C)cc1 nan
CHEMBL1484851 40703 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 2 6 3.5 CCOc1ccc(NC(=O)c2sc(NC(C)=O)c(C(=O)OC)c2C)cc1 nan
16023029 40835 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 6 2.9 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccc(F)cc2)s1 nan
CHEMBL1486082 40835 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 6 2.9 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccc(F)cc2)s1 nan
2122608 40859 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 6 1 5 4.1 CC(=O)c1sc(NC(=O)COc2ccc(C(C)C)c(C)c2)nc1C nan
CHEMBL1486351 40859 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 6 1 5 4.1 CC(=O)c1sc(NC(=O)COc2ccc(C(C)C)c(C)c2)nc1C nan
15988496 40901 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 6 0 6 5.2 CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(-c2ccc(F)c(Cl)c2)c(=O)c2sc3ccccc3c21 nan
CHEMBL1486634 40901 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 6 0 6 5.2 CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(-c2ccc(F)c(Cl)c2)c(=O)c2sc3ccccc3c21 nan
5058050 41007 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 7 0 5 4.0 CCCCN(CCCC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1487547 41007 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 7 0 5 4.0 CCCCN(CCCC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
1120443 41131 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 1 7 5.9 CCOc1cc(-c2nc3c(c(CC)nn3-c3ccccc3)c3cc(OC)c(OC)cc23)ccc1O nan
CHEMBL1488401 41131 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 1 7 5.9 CCOc1cc(-c2nc3c(c(CC)nn3-c3ccccc3)c3cc(OC)c(OC)cc23)ccc1O nan
1415522 41210 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 5 6.4 CCN(CC)C(=O)c1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N nan
CHEMBL1488995 41210 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 5 6.4 CCN(CC)C(=O)c1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N nan
2014552 41326 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 2 9 2.0 CCOc1cc(C2C(C#N)=C(N)SC(N)=C2C#N)ccc1OCCN1CCOCC1 nan
CHEMBL1489906 41326 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 2 9 2.0 CCOc1cc(C2C(C#N)=C(N)SC(N)=C2C#N)ccc1OCCN1CCOCC1 nan
2873834 41401 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 1 7 4.3 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccccc3c2=O)C2=C(O)CCCC2=N1 nan
CHEMBL1490473 41401 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 1 7 4.3 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccccc3c2=O)C2=C(O)CCCC2=N1 nan
1536777 41645 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 5 4.4 Cc1sc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2c1C nan
CHEMBL1492096 41645 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 5 4.4 Cc1sc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2c1C nan
2419865 41745 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 5 0 5 3.7 COc1ccc(C(C)=O)cc1COc1nc(C)nc2ccccc12 nan
CHEMBL1492888 41745 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 5 0 5 3.7 COc1ccc(C(C)=O)cc1COc1nc(C)nc2ccccc12 nan
1102906 41753 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 2 4 3.0 O=C(O)c1ccc(N2C(=O)c3cccc4c(C(=O)O)ccc(c34)C2=O)cc1 nan
CHEMBL1492995 41753 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 2 4 3.0 O=C(O)c1ccc(N2C(=O)c3cccc4c(C(=O)O)ccc(c34)C2=O)cc1 nan
3467703 41833 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 2 0 2 3.4 C=CCN1C(=O)c2cccc3c(Br)ccc(c23)C1=O nan
CHEMBL1493801 41833 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 2 0 2 3.4 C=CCN1C(=O)c2cccc3c(Br)ccc(c23)C1=O nan
7711621 41854 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 2 7 -0.5 CC(=O)Nc1ccc(S(=O)(=O)NCc2cc(=O)n(C)c(=O)n2C)cc1 nan
CHEMBL1494013 41854 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 2 7 -0.5 CC(=O)Nc1ccc(S(=O)(=O)NCc2cc(=O)n(C)c(=O)n2C)cc1 nan
681202 41923 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 3 3 3 3.6 Cc1sc(N=C(S)Nc2ccc(F)cc2)c(C(N)=O)c1C nan
CHEMBL1494694 41923 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 3 3 3 3.6 Cc1sc(N=C(S)Nc2ccc(F)cc2)c(C(N)=O)c1C nan
2451170 42003 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 1 6 2.8 CCOC(=O)c1sc2nc(C)nc(S)c2c1C nan
CHEMBL1495560 42003 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 1 6 2.8 CCOC(=O)c1sc2nc(C)nc(S)c2c1C nan
16017877 42045 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 0 4 2.6 Cc1ccccc1Cn1ccn(-c2ccc(F)c(F)c2)c(=O)c1=O nan
CHEMBL1495957 42045 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 0 4 2.6 Cc1ccccc1Cn1ccn(-c2ccc(F)c(F)c2)c(=O)c1=O nan
2917647 42168 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 6 3.5 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(Cl)cc1)c1ccco1 nan
CHEMBL1497016 42168 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 6 3.5 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(Cl)cc1)c1ccco1 nan
3493986 42189 8 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 8 1 6 5.3 CCOc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3ccccc3C)cc2)cc1 nan
CHEMBL1497174 42189 8 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 8 1 6 5.3 CCOc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3ccccc3C)cc2)cc1 nan
4260589 42226 5 None -5 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 9 2 6 4.8 CCCC1(c2ccccc2)NC(=O)N(CC(=O)Nc2sc(-c3ccccc3)cc2C(=O)OCC)C1=O nan
CHEMBL1497431 42226 5 None -5 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 9 2 6 4.8 CCCC1(c2ccccc2)NC(=O)N(CC(=O)Nc2sc(-c3ccccc3)cc2C(=O)OCC)C1=O nan
1234241 42287 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 1 1 5 2.9 Cc1nnc(S)c2nn(-c3ccccc3F)c(C)c12 nan
CHEMBL1498110 42287 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 1 1 5 2.9 Cc1nnc(S)c2nn(-c3ccccc3F)c(C)c12 nan
4056802 42490 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 2.8 Cc1cccn2c(=O)c3cc(C(=O)NCCCOC(C)C)sc3nc12 nan
CHEMBL1499876 42490 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 2.8 Cc1cccn2c(=O)c3cc(C(=O)NCCCOC(C)C)sc3nc12 nan
2908462 42495 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 7 1 6 3.1 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccccc1)c1ccco1 nan
CHEMBL1499902 42495 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 7 1 6 3.1 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccccc1)c1ccco1 nan
2551439 42627 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 0 8 1.7 COc1ccc(OCCOC(=O)c2nc3nccc(C)n3n2)cc1 nan
CHEMBL1501099 42627 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 0 8 1.7 COc1ccc(OCCOC(=O)c2nc3nccc(C)n3n2)cc1 nan
716763 42651 29 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 3.3 O=C(O)c1ccc(N2C(=O)c3cccc4cccc(c34)C2=O)cc1 nan
CHEMBL1501298 42651 29 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 3.3 O=C(O)c1ccc(N2C(=O)c3cccc4cccc(c34)C2=O)cc1 nan
5012247 42702 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 0 11 -2.0 CCN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1CCS(=O)(=O)C1 nan
CHEMBL1501780 42702 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 0 11 -2.0 CCN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1CCS(=O)(=O)C1 nan
2816746 43041 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 2 6 4.1 CCOC(=O)c1c(N=C(S)NCc2ccccc2)sc2c1CCN(C(=O)OCC)C2 nan
CHEMBL1504775 43041 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 2 6 4.1 CCOC(=O)c1c(N=C(S)NCc2ccccc2)sc2c1CCN(C(=O)OCC)C2 nan
2363951 43055 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 9 0.2 Cn1c(N)c(C(=O)COC(=O)CCC(=O)c2ccc(F)cc2)c(=O)n(C)c1=O nan
CHEMBL1504909 43055 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 9 0.2 Cn1c(N)c(C(=O)COC(=O)CCC(=O)c2ccc(F)cc2)c(=O)n(C)c1=O nan
3238944 43102 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 1 6 3.4 Cc1cccc(Nc2nn3c(=O)c4ccccc4nc3s2)c1 nan
CHEMBL1505300 43102 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 1 6 3.4 Cc1cccc(Nc2nn3c(=O)c4ccccc4nc3s2)c1 nan
7190519 43148 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 9 2.4 O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1nccs1 nan
CHEMBL1505657 43148 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 9 2.4 O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1nccs1 nan
3154081 43361 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 8 4.0 CCCOc1cccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1507529 43361 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 8 4.0 CCCOc1cccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
1803037 43548 9 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 5 6.1 Cc1cccc(NC(=O)CSc2nc(C)c(CC(=O)c3ccc(Br)cc3)c(C)c2C#N)c1C nan
CHEMBL1509120 43548 9 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 5 6.1 Cc1cccc(NC(=O)CSc2nc(C)c(CC(=O)c3ccc(Br)cc3)c(C)c2C#N)c1C nan
3772923 43560 23 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 0 1 3 2.4 Cc1nc(S)c(C#N)c2c1CCCC2 nan
CHEMBL1509207 43560 23 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 0 1 3 2.4 Cc1nc(S)c(C#N)c2c1CCCC2 nan
3150659 43693 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.3 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCCC3 nan
CHEMBL1510456 43693 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.3 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCCC3 nan
2318166 43727 7 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 4.7 CC(C)c1ccc(-c2c(C#N)c(N)nc(SCC(=O)N3CCCCCC3)c2C#N)cc1 nan
CHEMBL1510689 43727 7 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 4.7 CC(C)c1ccc(-c2c(C#N)c(N)nc(SCC(=O)N3CCCCCC3)c2C#N)cc1 nan
4382156 43801 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 4 2.2 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccccc1F nan
CHEMBL1511309 43801 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 4 2.2 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccccc1F nan
5825936 43858 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 10 1 8 3.3 C=CCOc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
CHEMBL1511801 43858 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 10 1 8 3.3 C=CCOc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
1234706 43889 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 2 6 3.5 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nc(C)cc(C)n2)cc1 nan
CHEMBL1512389 43889 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 2 6 3.5 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nc(C)cc(C)n2)cc1 nan
18572258 43900 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 7 2.9 O=C(CSc1nnc2ccc(-c3ccc(Br)cc3)nn12)NCC1CCCO1 nan
CHEMBL1512477 43900 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 7 2.9 O=C(CSc1nnc2ccc(-c3ccc(Br)cc3)nn12)NCC1CCCO1 nan
7205055 43929 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 6 3.3 CCN1CCN(Cc2c(O)ccc3cc(-c4ccc(OC)cc4)c(=O)oc23)CC1 nan
CHEMBL1512819 43929 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 6 3.3 CCN1CCN(Cc2c(O)ccc3cc(-c4ccc(OC)cc4)c(=O)oc23)CC1 nan
53229784 43931 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1 nan
5457315 43931 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1 nan
CHEMBL1512839 43931 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1 nan
16026424 43965 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 0 7 3.4 COC(=O)c1sc2ccccc2c1S(=O)(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
CHEMBL1513424 43965 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 0 7 3.4 COC(=O)c1sc2ccccc2c1S(=O)(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
16019493 43980 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 3.6 Cc1ccc(S(=O)(=O)NCCc2nnc3ccc(SCc4ccccc4C)nn23)cc1 nan
CHEMBL1513611 43980 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 3.6 Cc1ccc(S(=O)(=O)NCCc2nnc3ccc(SCc4ccccc4C)nn23)cc1 nan
15989126 43984 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 11 2 7 4.7 Cc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
CHEMBL1513634 43984 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 11 2 7 4.7 Cc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
1252356 44000 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 1 6 5.5 Cc1cc(C)cc(NC(=O)CSc2oc(-c3ccccc3)nc2S(=O)(=O)c2ccccc2)c1 nan
CHEMBL1513969 44000 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 1 6 5.5 Cc1cc(C)cc(NC(=O)CSc2oc(-c3ccccc3)nc2S(=O)(=O)c2ccccc2)c1 nan
16406807 44004 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 3 6 2.7 CC[C@@H](C)[C@H](NC(=O)CNC(=O)Cc1c(C)c2c(cc(C)c3c(C)coc32)oc1=O)C(=O)O nan
CHEMBL1514043 44004 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 3 6 2.7 CC[C@@H](C)[C@H](NC(=O)CNC(=O)Cc1c(C)c2c(cc(C)c3c(C)coc32)oc1=O)C(=O)O nan
2135573 44035 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 514 8 1 8 4.1 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
CHEMBL1514550 44035 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 514 8 1 8 4.1 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
16018084 44077 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 COc1ccc(OC)c(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1515147 44077 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 COc1ccc(OC)c(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
4302940 44078 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 4 5.4 CCn1cc(CNC(=O)c2cc(-c3ccc(C)cc3)nc3ccc(Br)cc23)c(C)n1 nan
CHEMBL1515178 44078 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 4 5.4 CCn1cc(CNC(=O)c2cc(-c3ccc(C)cc3)nc3ccc(Br)cc23)c(C)n1 nan
15989010 44093 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 7 1 8 3.0 Cc1cccc(Cn2c(=O)n(CCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c1 nan
CHEMBL1515330 44093 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 7 1 8 3.0 Cc1cccc(Cn2c(=O)n(CCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c1 nan
20885696 44254 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 9 1 8 1.4 COc1ccc(CCNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1OC nan
CHEMBL1517314 44254 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 9 1 8 1.4 COc1ccc(CCNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1OC nan
1488779 44478 23 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 4 4.6 COc1ccc(Oc2nccc(-c3ccc(F)cc3)c2C#N)cc1 nan
CHEMBL1519391 44478 23 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 4 4.6 COc1ccc(Oc2nccc(-c3ccc(F)cc3)c2C#N)cc1 nan
3154197 44479 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 2 8 0.6 Cn1c(=O)c2c(ncn2CC(O)CNc2cccc(Cl)c2)n(C)c1=O nan
CHEMBL1519401 44479 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 2 8 0.6 Cn1c(=O)c2c(ncn2CC(O)CNc2cccc(Cl)c2)n(C)c1=O nan
5309980 44521 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 1 6 2.5 CC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(=O)O nan
CHEMBL1519790 44521 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 1 6 2.5 CC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(=O)O nan
20873023 44610 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 1 10 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2ccc(OC)cc2)c1=O nan
CHEMBL1520622 44610 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 1 10 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2ccc(OC)cc2)c1=O nan
135407280 44638 35 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 2 1 5 2.4 CSc1nc(O)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1520797 44638 35 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 2 1 5 2.4 CSc1nc(O)c(C#N)c(-c2ccccc2)n1 nan
2868262 44702 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 1 3 4.7 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1ccc(Br)cc1 nan
CHEMBL1521342 44702 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 1 3 4.7 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1ccc(Br)cc1 nan
646901 44753 3 None -4 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 3.6 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1cc(C)on1)OCO3 nan
CHEMBL1521729 44753 3 None -4 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 3.6 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1cc(C)on1)OCO3 nan
16012248 44769 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 5 5.0 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)Nc3ccc(C)c(Cl)c3)c(C)nc21 nan
CHEMBL1521906 44769 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 5 5.0 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)Nc3ccc(C)c(Cl)c3)c(C)nc21 nan
5086217 44791 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.6 CCOC(=O)c1c(N=C(S)Nc2ccc(F)cc2)sc2c1CCC2 nan
CHEMBL1522109 44791 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.6 CCOC(=O)c1c(N=C(S)Nc2ccc(F)cc2)sc2c1CCC2 nan
2929681 44863 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 2 7 2.6 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CCc4ccccc4)c3nc12 nan
CHEMBL1522811 44863 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 2 7 2.6 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CCc4ccccc4)c3nc12 nan
352022 44905 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 3 0 7 0.5 CCCSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1523163 44905 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 3 0 7 0.5 CCCSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
861889 44915 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 3 4.0 Cc1ccc2nc(SCC(=O)NC3CCCC3)c(C)cc2c1 nan
CHEMBL1523239 44915 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 3 4.0 Cc1ccc2nc(SCC(=O)NC3CCCC3)c(C)cc2c1 nan
4099138 44920 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 9 2 8 3.5 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1523295 44920 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 9 2 8 3.5 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1ccc2c(c1)OCO2 nan
5760985 45201 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 4 1 4 4.8 O=C(C1=C(O)C(=O)N(c2ccccn2)C1c1ccc(F)cc1)c1ccc(Br)cc1 nan
CHEMBL1525962 45201 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 4 1 4 4.8 O=C(C1=C(O)C(=O)N(c2ccccn2)C1c1ccc(F)cc1)c1ccc(Br)cc1 nan
3186625 45424 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 2 9 0.7 CC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
CHEMBL1527889 45424 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 2 9 0.7 CC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
1166606 45496 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 8 1 6 5.3 COc1ccc(NC(=O)CCSc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)n2)cc1 nan
CHEMBL1528550 45496 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 8 1 6 5.3 COc1ccc(NC(=O)CCSc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)n2)cc1 nan
1109837 45577 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.2 Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ncccc3o2)cc1 nan
CHEMBL1529226 45577 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.2 Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ncccc3o2)cc1 nan
4413149 45600 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 4 3.1 Cc1ccc(Cl)cc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
CHEMBL1529453 45600 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 4 3.1 Cc1ccc(Cl)cc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
6086754 45663 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.9 COc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1529980 45663 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.9 COc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
4881121 45703 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 0 7 2.0 CCc1cc2c(SCC(=O)N(C)C3CCS(=O)(=O)C3)ncnc2s1 nan
CHEMBL1530432 45703 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 0 7 2.0 CCc1cc2c(SCC(=O)N(C)C3CCS(=O)(=O)C3)ncnc2s1 nan
15988929 45756 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 12 2 8 3.7 COc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2)c(=O)c2sccc21 nan
CHEMBL1530799 45756 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 12 2 8 3.7 COc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2)c(=O)c2sccc21 nan
2956077 45823 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 3 3.4 COc1ccc2cc(Br)ccc2c1CC(=O)NCC1CCCO1 nan
CHEMBL1531449 45823 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 3 3.4 COc1ccc2cc(Br)ccc2c1CC(=O)NCC1CCCO1 nan
646794 46243 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 6 2.4 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1cccnc1)c1ccco1 nan
CHEMBL1535358 46243 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 6 2.4 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1cccnc1)c1ccco1 nan
9551120 46379 0 None -14 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 3.0 CCOC(=O)Cn1c(=S)[nH]c2c(oc3ccc(Cl)cc32)c1=O nan
CHEMBL1536779 46379 0 None -14 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 3.0 CCOC(=O)Cn1c(=S)[nH]c2c(oc3ccc(Cl)cc32)c1=O nan
5297702 46480 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 1 3 4.2 Nc1c2c(nc3cccc(Cl)c13)N(c1ccccc1)CC2 nan
CHEMBL1537611 46480 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 1 3 4.2 Nc1c2c(nc3cccc(Cl)c13)N(c1ccccc1)CC2 nan
5069161 46674 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccccc1Cl nan
CHEMBL1539200 46674 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccccc1Cl nan
1373674 46744 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 8 0.1 Cn1c(=O)c2c(nc(SCC(=O)NC3CCCC3)n2C)n(C)c1=O nan
CHEMBL1539818 46744 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 8 0.1 Cn1c(=O)c2c(nc(SCC(=O)NC3CCCC3)n2C)n(C)c1=O nan
20888840 46785 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 0 8 2.2 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(C)CC2)s1 nan
CHEMBL1540109 46785 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 0 8 2.2 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(C)CC2)s1 nan
2823604 46865 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 3 0 4 3.2 COC(=O)CSc1ccnc2cc(Cl)ccc12 nan
CHEMBL1540846 46865 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 3 0 4 3.2 COC(=O)CSc1ccnc2cc(Cl)ccc12 nan
2502748 46899 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 7 0 7 3.0 COc1cc(CN(C)Cc2cc(=O)n3ccsc3n2)ccc1OC(F)F nan
CHEMBL1541111 46899 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 7 0 7 3.0 COc1cc(CN(C)Cc2cc(=O)n3ccsc3n2)ccc1OC(F)F nan
3119316 46958 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 4 3.9 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(Br)cc2)cc1 nan
CHEMBL1541516 46958 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 4 3.9 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(Br)cc2)cc1 nan
4885704 47011 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccccc1F nan
CHEMBL1541978 47011 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccccc1F nan
20884256 47193 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 8 0.5 Cc1nn(CC(=O)NCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
CHEMBL1543621 47193 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 8 0.5 Cc1nn(CC(=O)NCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
1451421 47294 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 0 6 3.9 CCOC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1544289 47294 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 0 6 3.9 CCOC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
7120054 47370 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1cccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)c1 nan
CHEMBL1544911 47370 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1cccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)c1 nan
3192298 47390 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 215 2 0 5 1.3 Cc1nc2ccccn2c1C(=O)OCC#N nan
CHEMBL1545062 47390 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 215 2 0 5 1.3 Cc1nc2ccccn2c1C(=O)OCC#N nan
976399 47398 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 4 4.1 Cc1ccc(OC(=O)c2ccc3nc(C)sc3c2)cc1 nan
CHEMBL1545103 47398 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 4 4.1 Cc1ccc(OC(=O)c2ccc3nc(C)sc3c2)cc1 nan
3455851 47496 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 4 3.2 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(F)cc1 nan
CHEMBL1545899 47496 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 4 3.2 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(F)cc1 nan
2431161 47705 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 6 3.6 CC(C)[C@H](NC(=O)c1ccccc1Cl)C(=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1547817 47705 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 6 3.6 CC(C)[C@H](NC(=O)c1ccccc1Cl)C(=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
3111438 47761 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 0 4 3.2 CC(=O)OCCCN1C(=O)c2cccc3cc(Br)cc(c23)C1=O nan
CHEMBL1548381 47761 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 0 4 3.2 CC(=O)OCCCN1C(=O)c2cccc3cc(Br)cc(c23)C1=O nan
24792694 47762 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 6 1.9 Cn1c2ccccc2c2nnc(SCC(=O)NC3CC3)nc21 nan
CHEMBL1548382 47762 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 6 1.9 Cn1c2ccccc2c2nnc(SCC(=O)NC3CC3)nc21 nan
664646 47777 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 3.6 COc1ccc(C(=O)OCc2cc3cccc(C)c3nc2O)cc1 nan
CHEMBL1548510 47777 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 3.6 COc1ccc(C(=O)OCc2cc3cccc(C)c3nc2O)cc1 nan
839503 47798 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 3 3 3.0 O=C(Nc1ccccc1C(=O)O)c1ccc(NC(=O)C2CC2)cc1 nan
CHEMBL1548673 47798 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 3 3 3.0 O=C(Nc1ccccc1C(=O)O)c1ccc(NC(=O)C2CC2)cc1 nan
4839425 47891 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 0 10 0.2 CN(C)S(=O)(=O)c1cc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1Cl nan
CHEMBL1549482 47891 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 0 10 0.2 CN(C)S(=O)(=O)c1cc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1Cl nan
838258 47974 25 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 1 1 3 3.6 Sc1nc(-c2ccccc2)nc2ccccc12 nan
CHEMBL1550135 47974 25 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 1 1 3 3.6 Sc1nc(-c2ccccc2)nc2ccccc12 nan
2794423 48003 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 2 2.3 NC1=CC(=O)c2cccc3cccc1c23 nan
CHEMBL1550366 48003 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 2 2.3 NC1=CC(=O)c2cccc3cccc1c23 nan
16187761 48027 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 7 2.2 Cc1cc(C)n2nc(C(=O)N3CCCC(CNS(=O)(=O)c4cccs4)C3)cc2n1 nan
CHEMBL1550610 48027 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 7 2.2 Cc1cc(C)n2nc(C(=O)N3CCCC(CNS(=O)(=O)c4cccs4)C3)cc2n1 nan
4969856 48102 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 2 6 2.1 CC(=O)Nc1ccc(Nc2ncnc3c2cnn3C)cc1 nan
CHEMBL1551291 48102 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 2 6 2.1 CC(=O)Nc1ccc(Nc2ncnc3c2cnn3C)cc1 nan
16009663 48105 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 1 7 4.8 CSc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)c1 nan
CHEMBL1551326 48105 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 1 7 4.8 CSc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)c1 nan
7184893 48181 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 8 3.7 CCCCNc1nc2c(S(=O)(=O)c3ccc(C)cc3)nnn2c2ccsc12 nan
CHEMBL1552371 48181 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 8 3.7 CCCCNc1nc2c(S(=O)(=O)c3ccc(C)cc3)nnn2c2ccsc12 nan
1003444 48192 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 3 2 5 5.7 Nc1c(C(=O)Nc2ccc(Cl)cc2F)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1552586 48192 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 3 2 5 5.7 Nc1c(C(=O)Nc2ccc(Cl)cc2F)sc2nc(-c3cccs3)ccc12 nan
1841026 48222 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 0 8 1.6 CCOC(=O)/C(C#N)=C/c1c(N2CCN(CC)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1553005 48222 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 0 8 1.6 CCOC(=O)/C(C#N)=C/c1c(N2CCN(CC)CC2)nc2c(C)cccn2c1=O nan
15988107 48224 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 0 7 3.8 CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(Cc2ccccc2)c(=O)c2c1c1cc(OC)ccc1n2C nan
CHEMBL1553031 48224 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 0 7 3.8 CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(Cc2ccccc2)c(=O)c2c1c1cc(OC)ccc1n2C nan
16009750 48228 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 4.9 Cc1cccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)c1 nan
CHEMBL1553063 48228 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 4.9 Cc1cccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)c1 nan
15988172 48246 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 2 4 2.2 CCCCNC(=O)c1ccc2c(=O)n(-c3ccccc3)c(=O)[nH]c2c1 nan
CHEMBL1553275 48246 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 2 4 2.2 CCCCNC(=O)c1ccc2c(=O)n(-c3ccccc3)c(=O)[nH]c2c1 nan
135697665 48256 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 9 1.8 O=C(OCc1nc(O)c2sccc2n1)c1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1553392 48256 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 9 1.8 O=C(OCc1nc(O)c2sccc2n1)c1cccc(S(=O)(=O)N2CCOCC2)c1 nan
5927505 48450 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 523 7 1 7 4.1 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Br)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1556043 48450 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 523 7 1 7 4.1 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Br)c1)c1ccc2c(c1)OCCO2 nan
2195056 48483 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 2 4.7 O=C(Nc1ccc(F)cc1)c1ccc(COc2ccccc2)cc1 nan
CHEMBL1556330 48483 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 2 4.7 O=C(Nc1ccc(F)cc1)c1ccc(COc2ccccc2)cc1 nan
5301777 48500 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 2 6 5.9 COC(=O)c1ccccc1NC(=O)c1sc2nc(C)cc(C)c2c1NC(=O)c1ccccc1Cl nan
CHEMBL1556556 48500 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 2 6 5.9 COC(=O)c1ccccc1NC(=O)c1sc2nc(C)cc(C)c2c1NC(=O)c1ccccc1Cl nan
3404081 48523 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2c(C)cc(S)nc2c1 nan
CHEMBL1556798 48523 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2c(C)cc(S)nc2c1 nan
1348154 48530 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 4 4.9 O=C(Cc1ccc(Cl)cc1)Nc1ccc2nn(-c3ccc(Cl)cc3)nc2c1 nan
CHEMBL1556858 48530 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 4 4.9 O=C(Cc1ccc(Cl)cc1)Nc1ccc2nn(-c3ccc(Cl)cc3)nc2c1 nan
3708288 48542 7 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 1 4 7 2.3 N#Cc1c(N)nc2c3c(sc(=N)c2c1N)NC(=O)CC3c1ccccc1 nan
CHEMBL1556915 48542 7 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 1 4 7 2.3 N#Cc1c(N)nc2c3c(sc(=N)c2c1N)NC(=O)CC3c1ccccc1 nan
285470 48583 29 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CCNc1nc(Cl)nc(-c2cn(-c3ccccc3)c3ccccc23)n1 nan
CHEMBL1557270 48583 29 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CCNc1nc(Cl)nc(-c2cn(-c3ccccc3)c3ccccc23)n1 nan
16009846 48628 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 5 1 8 1.7 COc1ccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)c(OC)c1 nan
CHEMBL1557614 48628 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 5 1 8 1.7 COc1ccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)c(OC)c1 nan
16010737 48637 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 6 3.1 CCc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(C)cc3)c(=O)c3cccnc32)cc1 nan
CHEMBL1557693 48637 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 6 3.1 CCc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(C)cc3)c(=O)c3cccnc32)cc1 nan
3333649 48796 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 5 3.2 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)c1cccs1 nan
CHEMBL1559037 48796 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 5 3.2 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)c1cccs1 nan
1166246 48851 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 5.6 Cc1ccc(NC(=O)CCSc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2)c(C)c1 nan
CHEMBL1559537 48851 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 5.6 Cc1ccc(NC(=O)CCSc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2)c(C)c1 nan
16009080 49054 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 569 7 1 7 6.7 CCOc1ccc(-c2cc3nc(C4CCN(C(=O)OC(C)(C)C)CC4)c(C(=O)Nc4cccc(CC)c4)cn3n2)cc1 nan
CHEMBL1561508 49054 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 569 7 1 7 6.7 CCOc1ccc(-c2cc3nc(C4CCN(C(=O)OC(C)(C)C)CC4)c(C(=O)Nc4cccc(CC)c4)cn3n2)cc1 nan
3141845 49112 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 1 4 6.0 COc1cc(NC(=O)c2ccc(Cl)cc2Cl)ccc1-c1cc2ccccc2oc1=O nan
CHEMBL1562003 49112 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 1 4 6.0 COc1cc(NC(=O)c2ccc(Cl)cc2Cl)ccc1-c1cc2ccccc2oc1=O nan
2510921 49218 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 1 5 2.8 O=C(CNC(=O)C1CCCCC1)OCC(=O)c1ccc(Cl)s1 nan
CHEMBL1562941 49218 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 1 5 2.8 O=C(CNC(=O)C1CCCCC1)OCC(=O)c1ccc(Cl)s1 nan
4800554 49340 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 6 3.8 COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccc2nc(C)sc2c1 nan
CHEMBL1563979 49340 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 6 3.8 COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccc2nc(C)sc2c1 nan
16009343 49359 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 0 5 4.3 Cc1ccccc1OCc1cc(=O)n2c(-c3ccccc3)csc2n1 nan
CHEMBL1564149 49359 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 0 5 4.3 Cc1ccccc1OCc1cc(=O)n2c(-c3ccccc3)csc2n1 nan
4911790 49470 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 1 2 3.4 COc1ccc2cc(C(=O)N3CCc4ccccc4C3)[nH]c2c1 nan
CHEMBL1565220 49470 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 1 2 3.4 COc1ccc2cc(C(=O)N3CCc4ccccc4C3)[nH]c2c1 nan
974361 49526 12 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 6 3.9 Cc1onc(-c2ccccc2)c1C(=O)Nc1cccc2nsnc12 nan
CHEMBL1565576 49526 12 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 6 3.9 Cc1onc(-c2ccccc2)c1C(=O)Nc1cccc2nsnc12 nan
15989682 49553 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 8 1 8 3.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc1 nan
CHEMBL1565778 49553 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 8 1 8 3.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc1 nan
1977639 49556 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 5 5.2 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccccc2)cc1)c1ccccc1Cl nan
CHEMBL1565785 49556 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 5 5.2 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccccc2)cc1)c1ccccc1Cl nan
789538 49693 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 0 1 4 2.0 CC1=C(C)C(C)=C(C#N)C(=C(C#N)C#N)N1 nan
CHEMBL1566885 49693 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 0 1 4 2.0 CC1=C(C)C(C)=C(C#N)C(=C(C#N)C#N)N1 nan
3442888 49799 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 1 0 5 3.1 Cc1cccn2c(=O)c3cc(C(=O)N4CCCC(C)C4)sc3nc12 nan
CHEMBL1567700 49799 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 1 0 5 3.1 Cc1cccn2c(=O)c3cc(C(=O)N4CCCC(C)C4)sc3nc12 nan
16009353 50111 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 0 5 4.6 Cc1cccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1C nan
CHEMBL1570398 50111 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 0 5 4.6 Cc1cccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1C nan
16019299 50125 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 5 1 5 4.2 Cc1cc(C)c(NC(=O)CSc2ccc(-c3ccccn3)nn2)c(C)c1 nan
CHEMBL1570518 50125 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 5 1 5 4.2 Cc1cc(C)c(NC(=O)CSc2ccc(-c3ccccn3)nn2)c(C)c1 nan
4917201 50197 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 6 1.4 CC(C(=O)Nc1cccnc1)n1cc([N+](=O)[O-])cn1 nan
CHEMBL1571073 50197 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 6 1.4 CC(C(=O)Nc1cccnc1)n1cc([N+](=O)[O-])cn1 nan
15990163 50199 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 2 7 3.3 COc1ccc(S(=O)(=O)Nc2cc3c(cc2NCc2ccccc2)n(C)c(=O)n3C)cc1 nan
CHEMBL1571094 50199 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 2 7 3.3 COc1ccc(S(=O)(=O)Nc2cc3c(cc2NCc2ccccc2)n(C)c(=O)n3C)cc1 nan
16194623 50285 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 0 8 1.8 CC(=O)C(Sc1ccc2nnc(-c3cccnc3)n2n1)C(C)=O nan
CHEMBL1572020 50285 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 0 8 1.8 CC(=O)C(Sc1ccc2nnc(-c3cccnc3)n2n1)C(C)=O nan
135408736 50340 43 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 228 1 1 5 2.1 Sc1ncnc2c1cnn2-c1ccccc1 nan
CHEMBL1572500 50340 43 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 228 1 1 5 2.1 Sc1ncnc2c1cnn2-c1ccccc1 nan
2769007 50657 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 4 0 7 1.4 CCOC(=O)C(C)Sc1nc(=O)n2cc(C)ccc2n1 nan
CHEMBL1575703 50657 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 4 0 7 1.4 CCOC(=O)C(C)Sc1nc(=O)n2cc(C)ccc2n1 nan
2808306 50673 25 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 5 2 4 3.1 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)CCC(=O)O nan
CHEMBL1575844 50673 25 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 5 2 4 3.1 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)CCC(=O)O nan
4356534 50776 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 6 4.4 COc1ccc2nc(Cl)c(C3CC(c4ccco4)=NN3C(=O)CCCC(=O)O)cc2c1 nan
CHEMBL1576687 50776 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 6 4.4 COc1ccc2nc(Cl)c(C3CC(c4ccco4)=NN3C(=O)CCCC(=O)O)cc2c1 nan
22517522 50900 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 7 2.1 CC(Oc1ccccc1)C(=O)Nc1nnc(S(=O)(=O)N2CCCCC2)s1 nan
CHEMBL1577822 50900 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 7 2.1 CC(Oc1ccccc1)C(=O)Nc1nnc(S(=O)(=O)N2CCCCC2)s1 nan
20856926 51090 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 4 3.0 CC(=O)c1cccc(NC(=O)CNC(=O)c2cc3ccccc3o2)c1 nan
CHEMBL1579387 51090 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 4 3.0 CC(=O)c1cccc(NC(=O)CNC(=O)c2cc3ccccc3o2)c1 nan
4368409 51182 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 8 4.7 CCCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1580198 51182 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 8 4.7 CCCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
990451 51247 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 0 7 3.2 Cc1ccc(-n2nc3c(SCCN4CCOCC4)nnc(C)c3c2C)cc1 nan
CHEMBL1580766 51247 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 0 7 3.2 Cc1ccc(-n2nc3c(SCCN4CCOCC4)nnc(C)c3c2C)cc1 nan
661914 51335 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 3.7 COc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1581469 51335 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 3.7 COc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
679340 51347 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 1 2 6 1.8 Cc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)o1 nan
CHEMBL1581638 51347 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 1 2 6 1.8 Cc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)o1 nan
990454 51366 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 7 3.0 Cc1nnc(SCCN2CCOCC2)c2nn(-c3ccccc3F)c(C)c12 nan
CHEMBL1581794 51366 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 7 3.0 Cc1nnc(SCCN2CCOCC2)c2nn(-c3ccccc3F)c(C)c12 nan
2666708 51412 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 7 3.3 COc1cc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc(OC)c1C nan
CHEMBL1582108 51412 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 7 3.3 COc1cc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc(OC)c1C nan
1943119 51689 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 0 10 2.9 COCCn1c(-c2cc(OC)c(OC)c(OC)c2)nc2oc3cc(OC)ccc3c(=O)c2c1=O nan
CHEMBL1584456 51689 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 0 10 2.9 COCCn1c(-c2cc(OC)c(OC)c(OC)c2)nc2oc3cc(OC)ccc3c(=O)c2c1=O nan
5923696 51868 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 1 9 -0.3 N#C/C(=C\c1c(N2CCOCC2)nc2ccccn2c1=O)C(=O)NC1CCS(=O)(=O)C1 nan
CHEMBL1585817 51868 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 1 9 -0.3 N#C/C(=C\c1c(N2CCOCC2)nc2ccccn2c1=O)C(=O)NC1CCS(=O)(=O)C1 nan
11957204 51915 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 5.1 O=C(Nc1nccs1)c1cc2sccc2n1Cc1ccc(Cl)cc1 nan
CHEMBL1586282 51915 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 5.1 O=C(Nc1nccs1)c1cc2sccc2n1Cc1ccc(Cl)cc1 nan
2534667 51927 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 5 0 6 2.4 COc1ccc(C(C)=O)cc1COC(=O)c1cnc(C)cn1 nan
CHEMBL1586370 51927 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 5 0 6 2.4 COc1ccc(C(C)=O)cc1COC(=O)c1cnc(C)cn1 nan
2048070 51931 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 4 4.0 Cc1ccc(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)cc1C nan
CHEMBL1586414 51931 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 4 4.0 Cc1ccc(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)cc1C nan
4382155 51977 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 6 1 4 2.7 CCc1ccccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
CHEMBL1586776 51977 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 6 1 4 2.7 CCc1ccccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
3548898 52012 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 2 6 1.7 CC(=O)N1CCc2c(sc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)c2C(N)=O)C1 nan
CHEMBL1587022 52012 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 2 6 1.7 CC(=O)N1CCc2c(sc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)c2C(N)=O)C1 nan
3565925 52084 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.9 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCC(C)C3 nan
CHEMBL1587609 52084 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.9 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCC(C)C3 nan
661736 52103 14 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 6 3.5 Cc1ccccc1N1C(=O)CC(Sc2nnc(-c3ccccc3)o2)C1=O nan
CHEMBL1587764 52103 14 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 6 3.5 Cc1ccccc1N1C(=O)CC(Sc2nnc(-c3ccccc3)o2)C1=O nan
5919084 52156 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 7 2.9 O=C(C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccc(F)cc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1588231 52156 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 7 2.9 O=C(C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccc(F)cc1)c1ccc2c(c1)OCCO2 nan
859793 52184 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 0 9 -0.6 Cn1c(=O)c2c(nc(SCCN3CCOCC3)n2C)n(C)c1=O nan
CHEMBL1588519 52184 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 0 9 -0.6 Cn1c(=O)c2c(nc(SCCN3CCOCC3)n2C)n(C)c1=O nan
4203923 52254 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 4.4 CCN(CC)CCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1cccs1 nan
4573010 52254 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 4.4 CCN(CC)CCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1cccs1 nan
CHEMBL1589149 52254 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 4.4 CCN(CC)CCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1cccs1 nan
16016946 52335 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 5 4.5 Cc1c(Cl)cccc1NC(=O)Cn1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1589855 52335 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 5 4.5 Cc1c(Cl)cccc1NC(=O)Cn1nc(C)c2sc3ccccc3c2c1=O nan
16014998 52337 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2ccc(C)cc2)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1589876 52337 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2ccc(C)cc2)c(C#N)c(-c2ccccc2)n1 nan
16017572 52349 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 6 1.7 CCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
CHEMBL1589962 52349 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 6 1.7 CCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
16019870 52354 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 6 4.8 COc1ccc(OC)c(NC(=O)CSc2cn(CC(=O)N3CCCCCC3)c3ccccc23)c1 nan
CHEMBL1590046 52354 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 6 4.8 COc1ccc(OC)c(NC(=O)CSc2cn(CC(=O)N3CCCCCC3)c3ccccc23)c1 nan
8070199 52366 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 8 1 7 3.5 Cn1nnnc1SCCCNCc1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1590182 52366 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 8 1 7 3.5 Cn1nnnc1SCCCNCc1ccc(-c2ccc(Br)cc2)o1 nan
1252599 52385 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 7 1.9 COC(=O)c1cc(CN2C(=O)c3ccccc3C2=O)c(O)c([N+](=O)[O-])c1 nan
CHEMBL1590469 52385 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 7 1.9 COC(=O)c1cc(CN2C(=O)c3ccccc3C2=O)c(O)c([N+](=O)[O-])c1 nan
3438312 52404 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 2 5 3.3 COc1ccccc1Cn1c(=S)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O nan
CHEMBL1590737 52404 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 2 5 3.3 COc1ccccc1Cn1c(=S)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O nan
8391566 52432 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 0 7 2.5 Cc1nnc(SCc2cc(=O)n3c(C)cccc3n2)s1 nan
CHEMBL1590986 52432 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 0 7 2.5 Cc1nnc(SCc2cc(=O)n3c(C)cccc3n2)s1 nan
16017932 52460 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 4 1 6 5.8 CCN(CC)c1ccc2cc(-c3nc4sc5c(c4c(=O)[nH]3)CCC(C(C)(C)C)C5)c(=O)oc2c1 nan
CHEMBL1591378 52460 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 4 1 6 5.8 CCN(CC)c1ccc2cc(-c3nc4sc5c(c4c(=O)[nH]3)CCC(C(C)(C)C)C5)c(=O)oc2c1 nan
7152123 52558 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 6 4.3 COc1ccc(-c2cn3nc(SCC(=O)Nc4ccccc4F)ccc3n2)cc1 nan
CHEMBL1592684 52558 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 6 4.3 COc1ccc(-c2cn3nc(SCC(=O)Nc4ccccc4F)ccc3n2)cc1 nan
20885677 52582 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 6 1 6 1.3 Cc1nn(CCCC(=O)NCc2ccccc2)c(=O)c2nccn12 nan
CHEMBL1592977 52582 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 6 1 6 1.3 Cc1nn(CCCC(=O)NCc2ccccc2)c(=O)c2nccn12 nan
16403621 52585 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 1 7 3.0 COc1ccc(OC)c(/C=C2\Oc3cc(OCC(=O)N4CCC(C(=O)O)CC4)ccc3C2=O)c1 nan
CHEMBL1593051 52585 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 1 7 3.0 COc1ccc(OC)c(/C=C2\Oc3cc(OCC(=O)N4CCC(C(=O)O)CC4)ccc3C2=O)c1 nan
20893093 52594 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 3 1 7 3.0 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3cccc(Cl)c3C)sc2n1 nan
CHEMBL1593179 52594 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 3 1 7 3.0 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3cccc(Cl)c3C)sc2n1 nan
16018628 52654 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 0 7 5.4 Cc1oc(-c2ccccc2Cl)nc1CSc1nncn2c1cc1occc12 nan
CHEMBL1594061 52654 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 0 7 5.4 Cc1oc(-c2ccccc2Cl)nc1CSc1nncn2c1cc1occc12 nan
16025303 52805 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 7 1 6 5.2 Cc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
CHEMBL1595335 52805 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 7 1 6 5.2 Cc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
5310070 52813 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 0 8 1.8 CCOC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1595390 52813 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 0 8 1.8 CCOC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
15991139 52845 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 0 4 5.2 CCC(C)OC(=O)/C(C#N)=C\c1ccc(-c2cccc(C(F)(F)F)c2)o1 nan
CHEMBL1595672 52845 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 0 4 5.2 CCC(C)OC(=O)/C(C#N)=C\c1ccc(-c2cccc(C(F)(F)F)c2)o1 nan
5135766 52937 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 3 5.0 O=C(COc1ccc2oc3c(c2c1)CCCC3)Nc1ccc(Cl)cc1 nan
CHEMBL1596555 52937 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 3 5.0 O=C(COc1ccc2oc3c(c2c1)CCCC3)Nc1ccc(Cl)cc1 nan
3653425 53026 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 3.7 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)cc1 nan
661006 53026 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 3.7 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)cc1 nan
CHEMBL1597383 53026 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 3.7 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)cc1 nan
2991609 53030 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 7 2 4 1.6 Cc1ccc(OCC(=O)NCCNC(=O)c2cccnc2)cc1C nan
CHEMBL1597415 53030 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 7 2 4 1.6 Cc1ccc(OCC(=O)NCCNC(=O)c2cccnc2)cc1C nan
20893092 53089 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 1 7 2.4 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3ccccc3C)sc2n1 nan
CHEMBL1597947 53089 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 1 7 2.4 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3ccccc3C)sc2n1 nan
44666769 53111 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 6 0.9 Cc1cc(=O)oc2c(CN3CCN(CCO)CC3)c(O)ccc12 nan
5289738 53111 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 6 0.9 Cc1cc(=O)oc2c(CN3CCN(CCO)CC3)c(O)ccc12 nan
CHEMBL1598157 53111 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 6 0.9 Cc1cc(=O)oc2c(CN3CCN(CCO)CC3)c(O)ccc12 nan
5310246 53122 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 1 6 4.0 COc1ccc(-c2cn3c(C)c(C(=O)Nc4ccncc4)sc3n2)cc1 nan
CHEMBL1598249 53122 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 1 6 4.0 COc1ccc(-c2cn3c(C)c(C(=O)Nc4ccncc4)sc3n2)cc1 nan
2807627 53178 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 217 1 0 5 1.4 CC1CCCN(c2ccc3nncn3n2)C1 nan
CHEMBL1598761 53178 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 217 1 0 5 1.4 CC1CCCN(c2ccc3nncn3n2)C1 nan
22514515 53262 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 0 7 0.9 CCOC(=O)C1CCN(C(=O)Cn2nc(CC)n3cccc3c2=O)CC1 nan
CHEMBL1599442 53262 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 0 7 0.9 CCOC(=O)C1CCN(C(=O)Cn2nc(CC)n3cccc3c2=O)CC1 nan
2913046 53448 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 5 5.1 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)c(Cl)c2)o1 nan
CHEMBL1601179 53448 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 5 5.1 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)c(Cl)c2)o1 nan
3152554 53475 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.3 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1Cl)c1ccco1 nan
CHEMBL1601448 53475 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.3 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1Cl)c1ccco1 nan
3733422 53522 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 4.2 COc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1 nan
CHEMBL1602024 53522 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 4.2 COc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1 nan
3185717 53525 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 8 3.2 Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)c1C nan
CHEMBL1602063 53525 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 8 3.2 Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)c1C nan
1541054 53853 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 5 4.3 CCOc1cccc(NC(=O)CSc2nc(C)c3c(c2C#N)CCCC3)c1 nan
CHEMBL1604887 53853 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 5 4.3 CCOc1cccc(NC(=O)CSc2nc(C)c3c(c2C#N)CCCC3)c1 nan
20885689 53918 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
CHEMBL1605440 53918 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
2890303 54019 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 4 2.7 CC(=O)C1=C(O)C(=O)N(c2ccccn2)C1c1cccc(F)c1 nan
CHEMBL1606210 54019 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 4 2.7 CC(=O)C1=C(O)C(=O)N(c2ccccn2)C1c1cccc(F)c1 nan
16030495 54060 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 4 5.9 Cc1ccc(Cl)cc1NC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1606531 54060 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 4 5.9 Cc1ccc(Cl)cc1NC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
855274 54192 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 2 0 5 2.0 COc1ccc2cc(C#N)c(N3CCOCC3)nc2c1 nan
CHEMBL1607471 54192 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 2 0 5 2.0 COc1ccc2cc(C#N)c(N3CCOCC3)nc2c1 nan
3663093 54216 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 2 8 4.6 CCc1nnc(NC(=O)CSc2nc3c([nH]c4ccccc43)c(=O)n2-c2cc(C)cc(C)c2)s1 nan
CHEMBL1607685 54216 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 2 8 4.6 CCc1nnc(NC(=O)CSc2nc3c([nH]c4ccccc43)c(=O)n2-c2cc(C)cc(C)c2)s1 nan
889917 54317 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 5 1 3 3.7 CCc1c(SCCC(=O)O)nc2ccccc2c1C nan
CHEMBL1608598 54317 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 5 1 3 3.7 CCc1c(SCCC(=O)O)nc2ccccc2c1C nan
7120053 54468 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1cccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)c1 nan
CHEMBL1609827 54468 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1cccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)c1 nan
2371304 54507 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 6 2.8 O=C(CSc1ncnc2ccccc12)NCc1ccc2c(c1)OCO2 nan
CHEMBL1610145 54507 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 6 2.8 O=C(CSc1ncnc2ccccc12)NCc1ccc2c(c1)OCO2 nan
4380426 54554 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1nnc(-c2ccccc2Cl)s1)c1ccccc1F nan
CHEMBL1610533 54554 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1nnc(-c2ccccc2Cl)s1)c1ccccc1F nan
2813334 54638 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 6 3.2 CCOC(=O)C1CCCN(C(=O)c2csc(-c3ccc4c(c3)CCO4)n2)C1 nan
CHEMBL1611317 54638 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 6 3.2 CCOC(=O)C1CCCN(C(=O)c2csc(-c3ccc4c(c3)CCO4)n2)C1 nan
16014906 54684 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 2 3.7 Cc1ccc(CNC(=O)c2cc3cc(C)ccc3n2C)cc1 nan
CHEMBL1611737 54684 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 2 3.7 Cc1ccc(CNC(=O)c2cc3cc(C)ccc3n2C)cc1 nan
4853715 54695 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 5 3.6 CC(=O)c1sc(NC(=O)c2cnc(Cl)c(Cl)c2)nc1C nan
CHEMBL1611812 54695 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 5 3.6 CC(=O)c1sc(NC(=O)c2cnc(Cl)c(Cl)c2)nc1C nan
16009370 54708 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 0 5 5.3 O=c1cc(COc2ccc(Cl)cc2Cl)nc2scc(-c3ccccc3)n12 nan
CHEMBL1611935 54708 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 0 5 5.3 O=c1cc(COc2ccc(Cl)cc2Cl)nc2scc(-c3ccccc3)n12 nan
24892471 55005 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 9 1 5 6.4 CCCCNc1c(-c2ccc(SC(C)CC)c(OC)c2)nc2ccc(C)cn12 nan
CHEMBL1356182 55005 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 9 1 5 6.4 CCCCNc1c(-c2ccc(SC(C)CC)c(OC)c2)nc2ccc(C)cn12 nan
CHEMBL1616404 55005 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 9 1 5 6.4 CCCCNc1c(-c2ccc(SC(C)CC)c(OC)c2)nc2ccc(C)cn12 nan
24789689 55365 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 2 4 3.3 CC(=O)Nc1ccc(-c2sc(Nc3ccccc3)n[n+]2C)cc1 nan
CHEMBL1395742 55365 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 2 4 3.3 CC(=O)Nc1ccc(-c2sc(Nc3ccccc3)n[n+]2C)cc1 nan
CHEMBL1619301 55365 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 2 4 3.3 CC(=O)Nc1ccc(-c2sc(Nc3ccccc3)n[n+]2C)cc1 nan
6489920 55512 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 3 0 2 3.1 CCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
CHEMBL1428082 55512 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 3 0 2 3.1 CCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
CHEMBL1620517 55512 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 3 0 2 3.1 CCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
5064206 55560 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.9 Cc1cc[n+]2cc(-c3cccc([N+](=O)[O-])c3)c(-c3cccc([N+](=O)[O-])c3)cc2c1 nan
CHEMBL1455685 55560 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.9 Cc1cc[n+]2cc(-c3cccc([N+](=O)[O-])c3)c(-c3cccc([N+](=O)[O-])c3)cc2c1 nan
CHEMBL1621049 55560 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.9 Cc1cc[n+]2cc(-c3cccc([N+](=O)[O-])c3)c(-c3cccc([N+](=O)[O-])c3)cc2c1 nan
820476 55814 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 1 2.2 Nc1ccc2ccc3cccc[n+]3c2c1 nan
CHEMBL1522563 55814 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 1 2.2 Nc1ccc2ccc3cccc[n+]3c2c1 nan
CHEMBL1623170 55814 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 1 2.2 Nc1ccc2ccc3cccc[n+]3c2c1 nan
1560419 55818 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 7 2 4 3.4 O=C(O)CCCCCNc1ncnc2ccc(Br)cc12 nan
CHEMBL1517106 55818 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 7 2 4 3.4 O=C(O)CCCCCNc1ncnc2ccc(Br)cc12 nan
CHEMBL1623202 55818 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 7 2 4 3.4 O=C(O)CCCCCNc1ncnc2ccc(Br)cc12 nan
1567753 55830 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 7 1 5 3.7 COc1ccc(-c2nc(NCCCN(C)C)c3ccccc3n2)cc1 nan
CHEMBL1534121 55830 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 7 1 5 3.7 COc1ccc(-c2nc(NCCCN(C)C)c3ccccc3n2)cc1 nan
CHEMBL1623318 55830 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 7 1 5 3.7 COc1ccc(-c2nc(NCCCN(C)C)c3ccccc3n2)cc1 nan
818329 55995 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 4 4.0 Sc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1 nan
CHEMBL1568356 55995 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 4 4.0 Sc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1 nan
CHEMBL1624703 55995 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 4 4.0 Sc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1 nan
3146476 69782 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
5767654 69782 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
6248042 69782 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
CHEMBL193627 69782 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
CHEMBL584458 69782 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
2152519 71958 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 7 0 9 3.6 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1ccccc1OCC nan
CHEMBL1973861 71958 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 7 0 9 3.6 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1ccccc1OCC nan
2003230 72212 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 0 8 1.2 CCOC(=O)c1cc2c(=O)n3cccc(C)c3nc2n(CCOC)/c1=N\C(C)=O nan
CHEMBL1981685 72212 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 0 8 1.2 CCOC(=O)c1cc2c(=O)n3cccc(C)c3nc2n(CCOC)/c1=N\C(C)=O nan
9580624 72361 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 6 1 7 2.5 COc1cccc(/C=N/Nc2ncccc2[N+](=O)[O-])c1OC nan
CHEMBL1986514 72361 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 6 1 7 2.5 COc1cccc(/C=N/Nc2ncccc2[N+](=O)[O-])c1OC nan
9564678 72505 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 9 -0.4 COc1ccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1991163 72505 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 9 -0.4 COc1ccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
135406177 72529 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 2 2 4 3.6 Cc1ccc(O)c(/N=C/C2=C(O)c3ccccc3C2=O)c1 nan
CHEMBL1991885 72529 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 2 2 4 3.6 Cc1ccc(O)c(/N=C/C2=C(O)c3ccccc3C2=O)c1 nan
9583975 72616 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 2 6 5.8 Nc1c(C(=O)N/N=C/c2ccccc2Cl)oc2nc(-c3ccccc3)cc(-c3ccco3)c12 nan
CHEMBL1995041 72616 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 2 6 5.8 Nc1c(C(=O)N/N=C/c2ccccc2Cl)oc2nc(-c3ccccc3)cc(-c3ccco3)c12 nan
5936993 72787 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 0 2 6.9 CCN(CC)c1ccc(/C=C/c2cc(-c3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL2001294 72787 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 0 2 6.9 CCN(CC)c1ccc(/C=C/c2cc(-c3ccccc3)c3ccccc3n2)cc1 nan
735993 87981 41 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 1 4 3.1 CN(C)c1ccc(-c2nc3cc(N)ccc3o2)cc1 nan
CHEMBL234378 87981 41 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 1 4 3.1 CN(C)c1ccc(-c2nc3cc(N)ccc3o2)cc1 nan
9638128 107726 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 7 0 5 3.4 CCN(CC)c1ccc(C(=O)c2cnc(/N=C/N(C)C)s2)cc1 nan
CHEMBL3191439 107726 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 7 0 5 3.4 CCN(CC)c1ccc(C(=O)c2cnc(/N=C/N(C)C)s2)cc1 nan
24892228 107830 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 0 8 2.7 COCCn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2c(OC)ccc(OC)c21 nan
CHEMBL3192568 107830 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 0 8 2.7 COCCn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2c(OC)ccc(OC)c21 nan
46497908 107990 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 10 0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C\c2ccccc2[N+](=O)[O-])n(C)c1=O nan
CHEMBL3194459 107990 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 10 0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C\c2ccccc2[N+](=O)[O-])n(C)c1=O nan
135412189 108215 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 3 10 1.0 COc1cc(/C=N/Nc2nc(O)nnc2C)cc([N+](=O)[O-])c1O nan
CHEMBL3197005 108215 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 3 10 1.0 COc1cc(/C=N/Nc2nc(O)nnc2C)cc([N+](=O)[O-])c1O nan
4122444 108479 11 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 6 2.4 CCOC(=O)c1s/c(=N\C(=O)c2cccs2)n(C)c1C nan
CHEMBL3199794 108479 11 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 6 2.4 CCOC(=O)c1s/c(=N\C(=O)c2cccs2)n(C)c1C nan
5343366 108484 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 4 0 7 1.8 CSc1nncn1/N=C/c1ccc([N+](=O)[O-])cc1 nan
CHEMBL3199842 108484 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 4 0 7 1.8 CSc1nncn1/N=C/c1ccc([N+](=O)[O-])cc1 nan
135411619 108494 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 4 1 8 1.5 Cc1nn(-c2ccc([N+](=O)[O-])cc2)c(O)c1/C=N/N1CCOCC1 nan
CHEMBL3199911 108494 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 4 1 8 1.5 Cc1nn(-c2ccc([N+](=O)[O-])cc2)c(O)c1/C=N/N1CCOCC1 nan
9955 142312 101 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 135 0 2 4 -0.1 Nc1nc2ncnc-2c[nH]1 nan
CHEMBL1356616 142312 101 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 135 0 2 4 -0.1 Nc1nc2ncnc-2c[nH]1 nan
CHEMBL388594 142312 101 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 135 0 2 4 -0.1 Nc1nc2ncnc-2c[nH]1 nan
154730799 167652 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 8 1 7 4.0 CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 nan
65191 167652 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 8 1 7 4.0 CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 nan
CHEMBL1306565 167652 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 8 1 7 4.0 CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 nan
CHEMBL4302011 167652 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 8 1 7 4.0 CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 nan
21551 184226 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 2 0 6 0.6 Cn1c(=O)c2c(nc(Cc3ccccc3)n2C)n(C)c1=O nan
CHEMBL483661 184226 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 2 0 6 0.6 Cn1c(=O)c2c(nc(Cc3ccccc3)n2C)n(C)c1=O nan
4380636 200983 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 5.3 CC(C)c1ccc(Nc2c(-c3ccccn3)nc3ccccn23)cc1 nan
CHEMBL602150 200983 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 5.3 CC(C)c1ccc(Nc2c(-c3ccccn3)nc3ccccn23)cc1 nan
1499 2078 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
3779 2078 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
536 2078 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
CHEMBL434 2078 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
DB01064 2078 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
3762 14440 27 None 1 3 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 5 4 4 1.9 CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 nan
CHEMBL1201153 14440 27 None 1 3 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 5 4 4 1.9 CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 nan
CHEMBL1201213 14440 27 None 1 3 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 5 4 4 1.9 CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 nan
1214032 19730 13 None -2 2 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 526 6 1 7 6.1 CC1(C)Cc2nc3sc4c(SCC(=O)NC(c5ccccc5)c5ccccc5)ncnc4c3cc2CO1 nan
CHEMBL1301335 19730 13 None -2 2 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 526 6 1 7 6.1 CC1(C)Cc2nc3sc4c(SCC(=O)NC(c5ccccc5)c5ccccc5)ncnc4c3cc2CO1 nan
15990933 21741 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 2 3 6.2 CC(C)c1ccc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)cc1 nan
CHEMBL1319127 21741 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 2 3 6.2 CC(C)c1ccc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)cc1 nan
1716420 22040 14 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 5 6.5 COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)Nc4cccc(C(F)(F)F)c4)c(Br)c3n2)cc1 nan
CHEMBL1321710 22040 14 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 5 6.5 COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)Nc4cccc(C(F)(F)F)c4)c(Br)c3n2)cc1 nan
2919028 24341 15 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 10 3.9 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(OC)c(OC)c2)nc1C nan
CHEMBL1341127 24341 15 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 10 3.9 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(OC)c(OC)c2)nc1C nan
16019314 30869 12 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 5 1 9 4.9 COc1ccc(C)cc1Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 nan
CHEMBL1397774 30869 12 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 5 1 9 4.9 COc1ccc(C)cc1Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 nan
944832 31530 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 0 2 3 3.0 Sc1[nH]cnc2c3cc(Cl)ccc3nc1-2 nan
CHEMBL1404042 31530 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 0 2 3 3.0 Sc1[nH]cnc2c3cc(Cl)ccc3nc1-2 nan
4024853 31671 8 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.6 CCCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc(N(C)C)cc4)nc3c2)cc1 nan
CHEMBL1405437 31671 8 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.6 CCCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc(N(C)C)cc4)nc3c2)cc1 nan
24892224 34074 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 9 0.5 CC(C)c1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1425449 34074 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 9 0.5 CC(C)c1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
16033262 36243 1 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 1 5 5.9 Cc1c(C(=O)Nc2ccc(Br)cc2F)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1445708 36243 1 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 1 5 5.9 Cc1c(C(=O)Nc2ccc(Br)cc2F)sc2ncnc(N(C)C3CCCCC3)c12 nan
4179349 39565 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 8 1 7 5.6 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1473745 39565 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 8 1 7 5.6 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
2810065 42929 6 None 1 2 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 2 1 5 4.0 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)c1ccco1 nan
CHEMBL1503612 42929 6 None 1 2 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 2 1 5 4.0 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)c1ccco1 nan
16019583 44058 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 4 0 9 3.1 CCN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1514816 44058 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 4 0 9 3.1 CCN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
16023031 44592 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 6 3.1 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccc(F)cc3)s2)cc1 nan
CHEMBL1520434 44592 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 6 3.1 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccc(F)cc3)s2)cc1 nan
16030551 48092 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 4 5.1 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1 nan
CHEMBL1551173 48092 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 4 5.1 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1 nan
16009713 53948 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 4.9 COc1ccc(-c2nnn3c2nc(NCc2ccc(C)cc2)c2ccccc23)cc1 nan
CHEMBL1605623 53948 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 4.9 COc1ccc(-c2nnn3c2nc(NCc2ccc(C)cc2)c2ccccc23)cc1 nan
49858523 89505 0 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 0 5 5.0 CCCC[C@]12Cc3cc(C#N)ccc3[C@H](O1)c1c(cc(C)n(Cc3ccccc3)c1=O)O2 nan
CHEMBL2373613 89505 0 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 0 5 5.0 CCCC[C@]12Cc3cc(C#N)ccc3[C@H](O1)c1c(cc(C)n(Cc3ccccc3)c1=O)O2 nan
16010255 5940 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 7 5.1 Cc1ccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccc(Cl)cc23)c(C)c1 nan
CHEMBL1079970 5940 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 7 5.1 Cc1ccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccc(Cl)cc23)c(C)c1 nan
16010278 6099 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 7 4.4 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1cc(Cl)ccc12 nan
CHEMBL1080898 6099 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 7 4.4 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1cc(Cl)ccc12 nan
18560284 6314 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 7 1 8 3.3 O=C1CCCN1CCCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccccc12 nan
CHEMBL1082027 6314 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 7 1 8 3.3 O=C1CCCN1CCCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccccc12 nan
16010337 6352 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 4.1 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)C)c2cc(Cl)ccc23)cc1 nan
CHEMBL1082207 6352 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 4.1 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)C)c2cc(Cl)ccc23)cc1 nan
7185123 10645 6 None -851 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 nan
CHEMBL1170673 10645 6 None -851 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 nan
16019553 10674 6 None -912 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 8 4.4 CC(C)CCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 nan
CHEMBL1170871 10674 6 None -912 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 8 4.4 CC(C)CCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 nan
16019312 10866 1 None -144 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 9 4.2 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
CHEMBL1172727 10866 1 None -144 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 9 4.2 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
4968664 19667 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3cc(C)ccc3C)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1300883 19667 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3cc(C)ccc3C)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
16435505 19703 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CC3CCCO3)c(=O)n2c1 nan
CHEMBL1301161 19703 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CC3CCCO3)c(=O)n2c1 nan
1451395 19729 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.6 Cc1cccc(NC(=O)CSc2nc(COc3ccccc3)nc3ccccc23)c1C nan
CHEMBL1301326 19729 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.6 Cc1cccc(NC(=O)CSc2nc(COc3ccccc3)nc3ccccc23)c1C nan
1019237 19890 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 6 2 5 3.6 COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)n1 nan
CHEMBL1302646 19890 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 6 2 5 3.6 COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)n1 nan
1176215 20073 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 1 7 3.7 CCc1nnc(NC(=O)CSc2nc3cc(OC)ccc3cc2C)s1 nan
CHEMBL1304139 20073 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 1 7 3.7 CCc1nnc(NC(=O)CSc2nc3cc(OC)ccc3cc2C)s1 nan
706653 20079 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 1 1 5 3.5 N#Cc1c(-c2ccccc2)c(C#N)c2nc3ccccc3n2c1N nan
CHEMBL1304187 20079 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 1 1 5 3.5 N#Cc1c(-c2ccccc2)c(C#N)c2nc3ccccc3n2c1N nan
2060107 20125 6 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.7 COc1ccc(NC(=O)CSc2nnc(-c3cccs3)n2-c2ccccc2)cc1 nan
CHEMBL1304585 20125 6 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.7 COc1ccc(NC(=O)CSc2nnc(-c3cccs3)n2-c2ccccc2)cc1 nan
16034541 20336 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 6 3.5 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Br)s1 nan
CHEMBL1306241 20336 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 6 3.5 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Br)s1 nan
12005386 20418 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 6 4.7 CCCCOc1ccc(C(=O)Nn2c(-c3cccs3)nc3ccccc3c2=O)cc1 nan
CHEMBL1306967 20418 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 6 4.7 CCCCOc1ccc(C(=O)Nn2c(-c3cccs3)nc3ccccc3c2=O)cc1 nan
24818410 20670 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 6 0 6 4.2 COc1cccc(COC(=O)c2c(C)nn(-c3ccccc3)c2Cl)c1OC nan
CHEMBL1308959 20670 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 6 0 6 4.2 COc1cccc(COC(=O)c2c(C)nn(-c3ccccc3)c2Cl)c1OC nan
2081889 20943 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.1 Cc1sc2nc(SCC(=O)NCc3ccco3)n(Cc3ccccc3)c(=O)c2c1C nan
CHEMBL1311321 20943 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.1 Cc1sc2nc(SCC(=O)NCc3ccco3)n(Cc3ccccc3)c(=O)c2c1C nan
2102674 20969 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 3.6 Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(F)cc2)no1 nan
CHEMBL1311532 20969 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 3.6 Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(F)cc2)no1 nan
651309 21307 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 2.8 Cc1ccc2cc(C#N)c(SCC(=O)NCC3CCCO3)nc2c1 nan
CHEMBL1314039 21307 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 2.8 Cc1ccc2cc(C#N)c(SCC(=O)NCC3CCCO3)nc2c1 nan
16028453 21374 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 3 4 5.4 CCc1ccccc1NC(=O)Nc1cc(C(=O)NCc2ccc(OC)cc2)ccc1N1CCCC1 nan
CHEMBL1314777 21374 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 3 4 5.4 CCc1ccccc1NC(=O)Nc1cc(C(=O)NCc2ccc(OC)cc2)ccc1N1CCCC1 nan
15990013 21387 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 2 8 3.4 COc1ccccc1CNC(=O)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
CHEMBL1314976 21387 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 2 8 3.4 COc1ccccc1CNC(=O)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
16025439 21408 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 7 1 6 4.6 Cc1ccccc1CN1c2ccccc2-c2nc(SCC(=O)NCc3ccccc3)ncc2S1(=O)=O nan
CHEMBL1315303 21408 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 7 1 6 4.6 Cc1ccccc1CN1c2ccccc2-c2nc(SCC(=O)NCc3ccccc3)ncc2S1(=O)=O nan
18579745 21430 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 7 2.9 CCOC(=O)c1nn(-c2ccc(F)cc2)c(=O)cc1OCC(=O)Nc1cccc(C)c1 nan
CHEMBL1315496 21430 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 7 2.9 CCOC(=O)c1nn(-c2ccc(F)cc2)c(=O)cc1OCC(=O)Nc1cccc(C)c1 nan
135455826 21481 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 1 5 4.9 Cc1ccc(-c2cc(C(F)F)nc3sc4c(O)ncnc4c23)cc1 nan
CHEMBL1316104 21481 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 1 5 4.9 Cc1ccc(-c2cc(C(F)F)nc3sc4c(O)ncnc4c23)cc1 nan
16008870 21495 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 2 1 4 3.9 Cn1c(C(=O)Nc2cccc(Cl)c2)cc2c(=O)n(C)c3ccccc3c21 nan
CHEMBL1316241 21495 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 2 1 4 3.9 Cn1c(C(=O)Nc2cccc(Cl)c2)cc2c(=O)n(C)c3ccccc3c21 nan
16024585 21500 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 3.5 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NC3CCCCC3)c2n1 nan
CHEMBL1316336 21500 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 3.5 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NC3CCCCC3)c2n1 nan
16023032 21504 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 2 5 4.7 CC(=O)c1ccc(NC(=O)c2cccc(NC(=O)N3CCSc4ncccc43)c2)cc1 nan
CHEMBL1316423 21504 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 2 5 4.7 CC(=O)c1ccc(NC(=O)c2cccc(NC(=O)N3CCSc4ncccc43)c2)cc1 nan
937929 21517 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 4 3.6 Cc1nc(N)c(C#N)c(-c2cccnc2)c1-c1ccccc1 nan
CHEMBL1316609 21517 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 4 3.6 Cc1nc(N)c(C#N)c(-c2cccnc2)c1-c1ccccc1 nan
16009522 21554 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 Cc1csc2nc(COc3ccc(NC(=O)COc4ccccc4)cc3)cc(=O)n12 nan
CHEMBL1317126 21554 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 Cc1csc2nc(COc3ccc(NC(=O)COc4ccccc4)cc3)cc(=O)n12 nan
16020239 21619 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 527 6 1 5 5.2 Cc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3n(Cc3cccc(F)c3)c2=O)cc1 nan
CHEMBL1317963 21619 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 527 6 1 5 5.2 Cc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3n(Cc3cccc(F)c3)c2=O)cc1 nan
16022974 21620 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 5 1 6 4.8 Cc1nnc(N2CCC(C(=O)NCc3ccc(F)cc3)CC2)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
CHEMBL1317977 21620 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 5 1 6 4.8 Cc1nnc(N2CCC(C(=O)NCc3ccc(F)cc3)CC2)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
3450154 21656 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 6 2.6 CC(=O)c1sc(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2F)nc1C nan
CHEMBL1318435 21656 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 6 2.6 CC(=O)c1sc(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2F)nc1C nan
15988872 21657 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 6 5.4 CCOC(=O)c1c(NC(=O)c2cc(-c3ccc(Cl)cc3)on2)sc2c1CCCC2 nan
CHEMBL1318439 21657 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 6 5.4 CCOC(=O)c1c(NC(=O)c2cc(-c3ccc(Cl)cc3)on2)sc2c1CCCC2 nan
16008607 21660 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 6 1.6 Cc1nc2c(c(C)c1CCC(=O)NCc1ccc(F)cc1)c(=O)n(C)c(=O)n2C nan
CHEMBL1318457 21660 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 6 1.6 Cc1nc2c(c(C)c1CCC(=O)NCc1ccc(F)cc1)c(=O)n(C)c(=O)n2C nan
15991398 21678 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 4 6.3 Cc1ccc(NC(=O)c2cc3c(-c4ccccc4)nn(-c4ccccc4)c3s2)cc1 nan
CHEMBL1318575 21678 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 4 6.3 Cc1ccc(NC(=O)c2cc3c(-c4ccccc4)nn(-c4ccccc4)c3s2)cc1 nan
3144686 21705 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 4 4.3 CCC(C)NC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1 nan
CHEMBL1318807 21705 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 4 4.3 CCC(C)NC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1 nan
1329083 21751 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 4 4.7 Cc1cccc(C)c1NC(=O)COc1ccccc1C(=O)Nc1ccc(Br)cn1 nan
CHEMBL1319204 21751 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 4 4.7 Cc1cccc(C)c1NC(=O)COc1ccccc1C(=O)Nc1ccc(Br)cn1 nan
1983515 21779 8 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 6 1 6 5.3 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccs1 nan
CHEMBL1319447 21779 8 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 6 1 6 5.3 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccs1 nan
20889080 21825 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 4.1 CC(CNc1nc2ccc(Cl)cc2n2cnnc12)c1ccccc1 nan
CHEMBL1319804 21825 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 4.1 CC(CNc1nc2ccc(Cl)cc2n2cnnc12)c1ccccc1 nan
16017559 21931 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N3CCC(C)CC3)s2)c1 nan
CHEMBL1320668 21931 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N3CCC(C)CC3)s2)c1 nan
16029569 22069 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 5 4.5 Cc1cc2c(=O)c(C(=O)c3ccncc3)cn(CC(=O)Nc3cccc(C)c3C)c2cc1C nan
CHEMBL1321921 22069 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 5 4.5 Cc1cc2c(=O)c(C(=O)c3ccncc3)cn(CC(=O)Nc3cccc(C)c3C)c2cc1C nan
15989030 22101 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 9 2 7 3.9 Cc1ccc(CNC(=O)CCCn2c(=O)c3sccc3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1 nan
CHEMBL1322214 22101 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 9 2 7 3.9 Cc1ccc(CNC(=O)CCCn2c(=O)c3sccc3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1 nan
4412940 22166 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 5.1 CCOc1ccc(-n2cc(C(=O)Nc3ccccc3OCC)c3cc(OC)c(OC)cc3c2=O)cc1 nan
CHEMBL1322786 22166 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 5.1 CCOc1ccc(-n2cc(C(=O)Nc3ccccc3OCC)c3cc(OC)c(OC)cc3c2=O)cc1 nan
3197538 22214 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 5.3 CCCc1nc(SCC(=O)N2c3ccccc3CC2C)c2c(C)c(C)sc2n1 nan
CHEMBL1323376 22214 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 5.3 CCCc1nc(SCC(=O)N2c3ccccc3CC2C)c2c(C)c(C)sc2n1 nan
3223224 22343 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 2.5 Cc1ccnc(N2CCC(C(=O)NCc3ccccc3F)CC2)n1 nan
CHEMBL1324395 22343 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 2.5 Cc1ccnc(N2CCC(C(=O)NCc3ccccc3F)CC2)n1 nan
16025301 22354 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 594 8 1 8 5.4 CCOC(=O)c1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)c1 nan
CHEMBL1324479 22354 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 594 8 1 8 5.4 CCOC(=O)c1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)c1 nan
24818748 22397 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 3 5 3.9 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)c(OC)c1 nan
CHEMBL1324786 22397 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 3 5 3.9 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)c(OC)c1 nan
15991180 22472 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 4 6.4 CCOc1ccc(C(=O)Nc2ccc(Cl)c(-c3nc4cc(C)cc(C)c4o3)c2)cc1 nan
CHEMBL1325481 22472 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 4 6.4 CCOc1ccc(C(=O)Nc2ccc(Cl)c(-c3nc4cc(C)cc(C)c4o3)c2)cc1 nan
794333 22596 61 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 0 2 3.7 COc1ccc(C(=O)c2ccc(Br)cc2)cc1 nan
CHEMBL1326786 22596 61 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 0 2 3.7 COc1ccc(C(=O)c2ccc(Br)cc2)cc1 nan
16012102 22618 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
CHEMBL1326931 22618 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
2097459 22634 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 1 3 4.1 Cc1ccc(NC(=O)Cn2cc(C(F)(F)F)cc(Cl)c2=O)cc1Cl nan
CHEMBL1327066 22634 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 1 3 4.1 Cc1ccc(NC(=O)Cn2cc(C(F)(F)F)cc(Cl)c2=O)cc1Cl nan
15988236 22655 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 7 2.1 CCC(C)NC(=O)Cn1c(=O)n(-c2cc(OC)cc(OC)c2)c(=O)c2ccccc21 nan
CHEMBL1327218 22655 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 7 2.1 CCC(C)NC(=O)Cn1c(=O)n(-c2cc(OC)cc(OC)c2)c(=O)c2ccccc21 nan
6825246 22692 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 581 8 2 8 1.9 CCOc1ccc(-n2c([S-])c(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)[n+]3cc(C(N)=O)ccc23)cc1 nan
CHEMBL1327580 22692 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 581 8 2 8 1.9 CCOc1ccc(-n2c([S-])c(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)[n+]3cc(C(N)=O)ccc23)cc1 nan
3192843 22724 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 2 6 2.8 O=C(Cn1nnc(-c2ccccc2NC(=O)c2ccccc2F)n1)NC1CCCC1 nan
CHEMBL1327798 22724 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 2 6 2.8 O=C(Cn1nnc(-c2ccccc2NC(=O)c2ccccc2F)n1)NC1CCCC1 nan
2816102 22786 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 259 2 0 5 3.3 CCOc1ncnc2c1sc1nc(C)cc(C)c12 nan
CHEMBL1328179 22786 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 259 2 0 5 3.3 CCOc1ncnc2c1sc1nc(C)cc(C)c12 nan
16009635 22932 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 8 4.5 COc1ccc(C(=O)Nc2cccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)c2)cc1OC nan
CHEMBL1329536 22932 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 8 4.5 COc1ccc(C(=O)Nc2cccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)c2)cc1OC nan
753116 22993 57 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 3 4.3 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)o1 nan
CHEMBL1330042 22993 57 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 3 4.3 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)o1 nan
4246541 23102 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 4 4.9 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)Nc3ccc(Br)cc3F)c(C)c2c1 nan
CHEMBL1330918 23102 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 4 4.9 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)Nc3ccc(Br)cc3F)c(C)c2c1 nan
701957 23168 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 2 0 3 3.4 CCOc1cc(C)cc2oc(=O)c3c(c12)CCCC3 nan
CHEMBL1331353 23168 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 2 0 3 3.4 CCOc1cc(C)cc2oc(=O)c3c(c12)CCCC3 nan
16014559 23169 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.9 COc1ccc(-c2nc3nc(C)cc(Nc4cccc(C(F)(F)F)c4)n3n2)cc1 nan
CHEMBL1331359 23169 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.9 COc1ccc(-c2nc3nc(C)cc(Nc4cccc(C(F)(F)F)c4)n3n2)cc1 nan
16009329 23244 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 1 7 3.3 O=C(Cn1cc(S(=O)(=O)c2ccc(F)cc2)c(=O)c2cc3c(cc21)OCO3)Nc1ccccc1 nan
CHEMBL1331963 23244 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 1 7 3.3 O=C(Cn1cc(S(=O)(=O)c2ccc(F)cc2)c(=O)c2cc3c(cc21)OCO3)Nc1ccccc1 nan
2151601 23291 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 5.5 Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1332323 23291 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 5.5 Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 nan
5310234 23384 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 8 2.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)NCc1ccco1 nan
CHEMBL1333013 23384 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 8 2.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)NCc1ccco1 nan
16018028 23503 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 4 2.6 O=C(Cn1c(=O)c2cccn2c2ccccc21)NCCc1ccccc1 nan
CHEMBL1333957 23503 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 4 2.6 O=C(Cn1c(=O)c2cccn2c2ccccc21)NCCc1ccccc1 nan
3174233 23561 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 10 3 7 3.1 CCCCOc1ccc(N(CC(=O)NC2CCCCC2)C(=O)c2snc(C(N)=O)c2N)cc1 nan
CHEMBL1334365 23561 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 10 3 7 3.1 CCCCOc1ccc(N(CC(=O)NC2CCCCC2)C(=O)c2snc(C(N)=O)c2N)cc1 nan
2237458 23569 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 8 2.3 COCc1cc(C)nc(SCC(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)c1C#N nan
CHEMBL1334406 23569 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 8 2.3 COCc1cc(C)nc(SCC(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)c1C#N nan
16030555 23625 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 0 4 5.9 O=C(CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1)N1CCCc2ccccc21 nan
CHEMBL1334948 23625 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 0 4 5.9 O=C(CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1)N1CCCc2ccccc21 nan
1257917 23645 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 2 1 4 3.0 O=C(Nc1ccc(F)cc1F)c1cc2ncc(Br)cn2n1 nan
CHEMBL1335101 23645 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 2 1 4 3.0 O=C(Nc1ccc(F)cc1F)c1cc2ncc(Br)cn2n1 nan
16010812 23677 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 3 0 7 3.8 Fc1ccc(N2CCN(c3nc4ccccc4c4nc(-c5cccnc5)nn34)CC2)cc1 nan
CHEMBL1335280 23677 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 3 0 7 3.8 Fc1ccc(N2CCN(c3nc4ccccc4c4nc(-c5cccnc5)nn34)CC2)cc1 nan
16015336 23706 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 5.4 CCc1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccc5c(c4)OCO5)c3C)nc2C)cc1 nan
CHEMBL1335512 23706 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 5.4 CCc1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccc5c(c4)OCO5)c3C)nc2C)cc1 nan
1450291 23783 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)c2cc(C#N)c(SCC(=O)Nc3cc(C)on3)nc2c1 nan
CHEMBL1336163 23783 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)c2cc(C#N)c(SCC(=O)Nc3cc(C)on3)nc2c1 nan
5115564 23787 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 3 7 5.7 N#Cc1ccccc1NC(=O)C1SC(Nc2ccccc2)=C(c2nc3ccccc3s2)C1=N nan
CHEMBL1336187 23787 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 3 7 5.7 N#Cc1ccccc1NC(=O)C1SC(Nc2ccccc2)=C(c2nc3ccccc3s2)C1=N nan
1366812 24126 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 4 5.3 Cc1ccc(-c2nc3ccccc3s2)cc1NC(=O)COc1ccccc1 nan
CHEMBL1339140 24126 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 4 5.3 Cc1ccc(-c2nc3ccccc3s2)cc1NC(=O)COc1ccccc1 nan
1860843 24253 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 2 5 5.2 Nc1c(C(=O)Nc2ccc(Br)cc2)sc2nc(-c3ccco3)ccc12 nan
CHEMBL1340363 24253 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 2 5 5.2 Nc1c(C(=O)Nc2ccc(Br)cc2)sc2nc(-c3ccco3)ccc12 nan
1258323 24319 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 2 6 3.6 Nc1c(C(=O)NCCc2ccccc2)sc2nc(N3CCOCC3)c3c(c12)CCCC3 nan
CHEMBL1340956 24319 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 2 6 3.6 Nc1c(C(=O)NCCc2ccccc2)sc2nc(N3CCOCC3)c3c(c12)CCCC3 nan
1248113 24331 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 0 7 3.3 CCOC(=O)c1cc(OC(=O)c2cccs2)n(-c2ccccc2)n1 nan
CHEMBL1341066 24331 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 0 7 3.3 CCOC(=O)c1cc(OC(=O)c2cccs2)n(-c2ccccc2)n1 nan
2478762 24579 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 6 3.3 Cc1c(C(=O)OCC(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2c1ccc1ccccc12 nan
CHEMBL1343023 24579 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 6 3.3 Cc1c(C(=O)OCC(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2c1ccc1ccccc12 nan
3243891 24592 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 6 2.6 Cc1ccc(CNc2nc3ccccc3n3nnnc23)cc1 nan
CHEMBL1343134 24592 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 6 2.6 Cc1ccc(CNc2nc3ccccc3n3nnnc23)cc1 nan
2242090 24785 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 2 5 3.5 CS(=O)(=O)c1ccc2nc(NC(=O)Nc3ccccc3F)sc2c1 nan
CHEMBL1344848 24785 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 2 5 3.5 CS(=O)(=O)c1ccc2nc(NC(=O)Nc3ccccc3F)sc2c1 nan
665134 24821 7 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 3.7 O=C1CC(c2ccc(F)cc2)Cc2nc(NCc3ccco3)ncc21 nan
CHEMBL1345142 24821 7 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 3.7 O=C1CC(c2ccc(F)cc2)Cc2nc(NCc3ccco3)ncc21 nan
1096895 24870 48 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 2 5 0.6 O=C(O)c1nn2cc(CCO)cnc2c1Cl nan
CHEMBL1345601 24870 48 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 2 5 0.6 O=C(O)c1nn2cc(CCO)cnc2c1Cl nan
3640616 24941 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 6 3.4 O=C(OC1CCOC1=O)c1cc(-c2cccs2)nc2ccccc12 nan
CHEMBL1346240 24941 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 6 3.4 O=C(OC1CCOC1=O)c1cc(-c2cccs2)nc2ccccc12 nan
4846975 25113 22 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 3 4.5 Sc1ncc(-c2ccc(Cl)cc2)n1-c1ccccc1 nan
CHEMBL1347553 25113 22 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 3 4.5 Sc1ncc(-c2ccc(Cl)cc2)n1-c1ccccc1 nan
5219047 25159 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 5 2 4 2.1 CCC(C)NC(=O)COC(=O)c1ccc(Cl)cc1O nan
CHEMBL1347937 25159 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 5 2 4 2.1 CCC(C)NC(=O)COC(=O)c1ccc(Cl)cc1O nan
16193959 25195 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 563 11 2 9 2.0 NS(=O)(=O)c1ccc(CCNC(=O)CCCn2c(SCC(=O)N3CCCC3)nc3ccsc3c2=O)cc1 nan
CHEMBL1348274 25195 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 563 11 2 9 2.0 NS(=O)(=O)c1ccc(CCNC(=O)CCCn2c(SCC(=O)N3CCCC3)nc3ccsc3c2=O)cc1 nan
3342394 25440 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 1 5 3.3 C=CCN1C(=O)c2ccccc2Sc2ccc(C(=O)NCC(OC)OC)cc21 nan
CHEMBL1350401 25440 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 1 5 3.3 C=CCN1C(=O)c2ccccc2Sc2ccc(C(=O)NCC(OC)OC)cc21 nan
16011056 25942 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 6 4.1 CCc1cc2c(cc3c(=O)n(CCCC(=O)NCc4cccc(Br)c4)ncn32)s1 nan
CHEMBL1354311 25942 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 6 4.1 CCc1cc2c(cc3c(=O)n(CCCC(=O)NCc4cccc(Br)c4)ncn32)s1 nan
16025634 25951 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 4.1 Cc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)cc1F nan
CHEMBL1354359 25951 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 4.1 Cc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)cc1F nan
16009946 25985 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 1.6 CCc1cccc(CC)c1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1354862 25985 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 1.6 CCc1cccc(CC)c1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
16018892 26009 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 0 7 5.9 CCc1nnc(SCc2nc(-c3ccccc3F)oc2C)c2cc3sccc3n12 nan
CHEMBL1355121 26009 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 0 7 5.9 CCc1nnc(SCc2nc(-c3ccccc3F)oc2C)c2cc3sccc3n12 nan
4363763 26080 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 5 0 8 4.0 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC2CCCO2)/c1=N\C(=O)c1ccc(C(C)(C)C)cc1 nan
CHEMBL1356044 26080 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 5 0 8 4.0 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC2CCCO2)/c1=N\C(=O)c1ccc(C(C)(C)C)cc1 nan
16024946 26096 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 1 4 4.1 O=C(NCc1ccccc1Cl)c1ccc2c(c1)nnn2C1CCCC1 nan
CHEMBL1356218 26096 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 1 4 4.1 O=C(NCc1ccccc1Cl)c1ccc2c(c1)nnn2C1CCCC1 nan
15990261 26099 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 7 4.1 Cc1nnc2c(N3CCN(c4ccccc4)CC3)nc3ccc(C(=O)c4ccccc4)cc3n12 nan
CHEMBL1356236 26099 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 7 4.1 Cc1nnc2c(N3CCN(c4ccccc4)CC3)nc3ccc(C(=O)c4ccccc4)cc3n12 nan
16031511 26103 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 6 4.1 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(F)cc3)s2)cc1 nan
CHEMBL1356303 26103 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 6 4.1 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(F)cc3)s2)cc1 nan
16030397 26119 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 5 3.4 COCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
CHEMBL1356573 26119 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 5 3.4 COCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
16009450 26136 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 7 3.5 O=C(COc1ccc(F)cc1)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1356791 26136 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 7 3.5 O=C(COc1ccc(F)cc1)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
756766 26148 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 1 4 3.8 Cn1c(SCc2cccc(F)c2)nc2c([nH]c3ccccc32)c1=O nan
CHEMBL1356946 26148 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 1 4 3.8 Cn1c(SCc2cccc(F)c2)nc2c([nH]c3ccccc32)c1=O nan
2141078 26160 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 6 4.7 COc1ccc(CNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1 nan
CHEMBL1357087 26160 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 6 4.7 COc1ccc(CNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1 nan
15988374 26191 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 569 6 0 6 5.7 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(F)cc1)S2(=O)=O)c1ccc(Br)cc1 nan
CHEMBL1357521 26191 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 569 6 0 6 5.7 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(F)cc1)S2(=O)=O)c1ccc(Br)cc1 nan
16020301 26205 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 2 7 4.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3ccc(F)cc3)c2=O)cc1 nan
CHEMBL1357758 26205 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 2 7 4.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3ccc(F)cc3)c2=O)cc1 nan
16024673 26215 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 6 3.9 COc1cccc(C(=O)c2cn(CC(=O)NCc3ccccc3Cl)c3nc(C)ccc3c2=O)c1 nan
CHEMBL1357949 26215 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 6 3.9 COc1cccc(C(=O)c2cn(CC(=O)NCc3ccccc3Cl)c3nc(C)ccc3c2=O)c1 nan
16016274 26233 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 0 6 4.2 Cc1cccc(-c2noc(-c3ccc(N4CCCC4)c([N+](=O)[O-])c3)n2)c1 nan
CHEMBL1358183 26233 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 0 6 4.2 Cc1cccc(-c2noc(-c3ccc(N4CCCC4)c([N+](=O)[O-])c3)n2)c1 nan
20880782 26245 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 1 7 3.0 CC1CCCCN1CCNC(=O)CCc1nnc2n(Cc3ccccc3)c(=O)c3ccccc3n12 nan
CHEMBL1358259 26245 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 1 7 3.0 CC1CCCCN1CCNC(=O)CCc1nnc2n(Cc3ccccc3)c(=O)c3ccccc3n12 nan
15988865 26261 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 1 5 3.6 Cc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1 nan
CHEMBL1358506 26261 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 1 5 3.6 Cc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1 nan
16009824 26278 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 6 2 7 4.0 NS(=O)(=O)c1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccc(Cl)cc23)cc1 nan
CHEMBL1358725 26278 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 6 2 7 4.0 NS(=O)(=O)c1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccc(Cl)cc23)cc1 nan
1231059 26281 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.7 CC(=O)Nc1cccc(-c2nnc(-c3ccc(C)cc3)o2)c1 nan
CHEMBL1358793 26281 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.7 CC(=O)Nc1cccc(-c2nnc(-c3ccc(C)cc3)o2)c1 nan
1317893 26325 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 5 5.2 Cc1cc(OCC(=O)Nc2cc(-c3nc4ncccc4o3)ccc2C)ccc1Cl nan
CHEMBL1359048 26325 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 5 5.2 Cc1cc(OCC(=O)Nc2cc(-c3nc4ncccc4o3)ccc2C)ccc1Cl nan
3410425 26440 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 0 7 3.7 CCOCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(OCC)ccc21 nan
CHEMBL1360046 26440 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 0 7 3.7 CCOCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(OCC)ccc21 nan
2335932 26522 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 2.8 Cc1cccc(C)c1NC(=O)COC(=O)c1ccc2c(c1)OCO2 nan
CHEMBL1360771 26522 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 2.8 Cc1cccc(C)c1NC(=O)COC(=O)c1ccc2c(c1)OCO2 nan
16009752 26585 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 5 4.5 CCCCNc1nc2c(-c3cccc(C)c3)nnn2c2ccccc12 nan
CHEMBL1361402 26585 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 5 4.5 CCCCNc1nc2c(-c3cccc(C)c3)nnn2c2ccccc12 nan
16022921 26598 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.7 CCOc1ccccc1CNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)CC1 nan
CHEMBL1361507 26598 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.7 CCOc1ccccc1CNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)CC1 nan
2345644 26670 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 7 3.5 COc1cccc(C(=O)Nc2nnc(-c3ccc(OC)cc3OC)s2)c1 nan
CHEMBL1362103 26670 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 7 3.5 COc1cccc(C(=O)Nc2nnc(-c3ccc(OC)cc3OC)s2)c1 nan
16022913 26713 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 6 4.3 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1362452 26713 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 6 4.3 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
1313404 26727 10 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 7 4.0 CCOc1cc(C2C(C(=O)OC)=CN(C3CCCC3)C=C2C(=O)OC)cc(Br)c1O nan
CHEMBL1362550 26727 10 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 7 4.0 CCOc1cc(C2C(C(=O)OC)=CN(C3CCCC3)C=C2C(=O)OC)cc(Br)c1O nan
3448294 26748 24 None -19 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 0 3 5.0 O=Cc1cc2ccccc2nc1SCc1ccc(Cl)cc1 nan
CHEMBL1362687 26748 24 None -19 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 0 3 5.0 O=Cc1cc2ccccc2nc1SCc1ccc(Cl)cc1 nan
16026537 26873 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 6 4.2 CC(=O)c1cccc(NC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)c1 nan
CHEMBL1363862 26873 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 6 4.2 CC(=O)c1cccc(NC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)c1 nan
16009886 26883 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 7 4.3 COc1cccc(-n2c(=O)c3sc4ccccc4c3n(CC(=O)Nc3ccccc3C)c2=O)c1 nan
CHEMBL1363941 26883 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 7 4.3 COc1cccc(-n2c(=O)c3sc4ccccc4c3n(CC(=O)Nc3ccccc3C)c2=O)c1 nan
3359750 26951 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.2 O=C(CSc1nc(-c2ccccc2)c2ccccc2n1)Nc1ccc(F)cc1 nan
CHEMBL1364552 26951 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.2 O=C(CSc1nc(-c2ccccc2)c2ccccc2n1)Nc1ccc(F)cc1 nan
16019445 27006 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 8 5.7 Cc1ccc(C)c(Nc2nc3c(S(=O)(=O)c4ccc(C(C)C)cc4)nnn3c3ccsc23)c1 nan
CHEMBL1365021 27006 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 8 5.7 Cc1ccc(C)c(Nc2nc3c(S(=O)(=O)c4ccc(C(C)C)cc4)nnn3c3ccsc23)c1 nan
1152421 27205 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 6 5.4 CCOc1ccccc1NC(=O)CSc1nc(-c2cccs2)cc(C(F)(F)F)n1 nan
CHEMBL1366693 27205 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 6 5.4 CCOc1ccccc1NC(=O)CSc1nc(-c2cccs2)cc(C(F)(F)F)n1 nan
1080694 27233 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 5 3.2 CC1(C)CC(=O)c2sc(NS(=O)(=O)c3ccc(F)cc3)nc2C1 nan
CHEMBL1366962 27233 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 5 3.2 CC1(C)CC(=O)c2sc(NS(=O)(=O)c3ccc(F)cc3)nc2C1 nan
16022984 27307 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.0 COc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1367585 27307 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.0 COc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
16015654 27460 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 6 1 5 4.7 CC(=O)Nc1ccc2nc(SCCOc3ccc(C)cc3)sc2c1 nan
CHEMBL1368731 27460 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 6 1 5 4.7 CC(=O)Nc1ccc2nc(SCCOc3ccc(C)cc3)sc2c1 nan
2918354 27755 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 5 3.7 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1cccc(Br)c1 nan
CHEMBL1370753 27755 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 5 3.7 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1cccc(Br)c1 nan
1005238 27791 19 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 7 3.5 Cc1cc(NC(=O)CSc2nc3c(c(-c4cccnc4)c2C#N)CCC3)no1 nan
CHEMBL1371055 27791 19 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 7 3.5 Cc1cc(NC(=O)CSc2nc3c(c(-c4cccnc4)c2C#N)CCC3)no1 nan
1442423 28089 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 6 4.0 Cc1cc(NC(=O)CSc2nc(C(C)(C)C)nc3ccccc23)no1 nan
CHEMBL1373175 28089 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 6 4.0 Cc1cc(NC(=O)CSc2nc(C(C)(C)C)nc3ccccc23)no1 nan
6615570 28146 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 4 1 7 3.7 COc1ccc(C)cc1NC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C nan
CHEMBL1373530 28146 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 4 1 7 3.7 COc1ccc(C)cc1NC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C nan
2410746 28166 41 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 2 5 3.0 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)cc1 nan
CHEMBL1373647 28166 41 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 2 5 3.0 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)cc1 nan
16009969 28293 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 7 1.3 CN(CC(=O)Nc1ccc(Cl)cc1F)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1374581 28293 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 7 1.3 CN(CC(=O)Nc1ccc(Cl)cc1F)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
9547710 28295 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 9 0.3 Cn1c(N)c(C(=O)COC(=O)c2ccnc3ccccc23)c(=O)n(C)c1=O nan
CHEMBL1374591 28295 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 9 0.3 Cn1c(N)c(C(=O)COC(=O)c2ccnc3ccccc23)c(=O)n(C)c1=O nan
4414022 28325 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 7 1 6 4.0 CCOC(=O)c1c(NC(=O)C(C)Oc2ccccc2F)sc(C(C)=O)c1C nan
CHEMBL1374782 28325 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 7 1 6 4.0 CCOC(=O)c1c(NC(=O)C(C)Oc2ccccc2F)sc(C(C)=O)c1C nan
679950 28388 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 2.9 CCN(CC)c1ccc(-c2c(C#N)c(N)nc(OC)c2C#N)cc1 nan
CHEMBL1375207 28388 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 2.9 CCN(CC)c1ccc(-c2c(C#N)c(N)nc(OC)c2C#N)cc1 nan
5297522 28399 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 2 7 4.0 CCOC(=O)c1ccc(NC(=O)c2sc3nc4c(cc3c2N)N2CCC4CC2)cc1 nan
CHEMBL1375280 28399 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 2 7 4.0 CCOC(=O)c1ccc(NC(=O)c2sc3nc4c(cc3c2N)N2CCC4CC2)cc1 nan
16022988 28446 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 7 2.8 CCNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(OC)cc4)nc23)CC1 nan
CHEMBL1375625 28446 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 7 2.8 CCNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(OC)cc4)nc23)CC1 nan
1224964 28450 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 2 3 4.2 O=C(Nc1ccc(C(=O)NC2CCCCC2)cc1)c1cncc(Br)c1 nan
CHEMBL1375663 28450 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 2 3 4.2 O=C(Nc1ccc(C(=O)NC2CCCCC2)cc1)c1cncc(Br)c1 nan
16009514 28533 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1ccc(C(=O)Nc2ccc(OCc3cc(=O)n4c(C)csc4n3)cc2)cc1 nan
CHEMBL1376473 28533 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1ccc(C(=O)Nc2ccc(OCc3cc(=O)n4c(C)csc4n3)cc2)cc1 nan
16010769 28606 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 3.6 Cc1ccc(Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cccnc32)cc1 nan
CHEMBL1377217 28606 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 3.6 Cc1ccc(Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cccnc32)cc1 nan
16024487 28660 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 1 5 4.2 Cc1cc(C)cc(NC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3ccc(C)nc32)c1 nan
CHEMBL1377738 28660 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 1 5 4.2 Cc1cc(C)cc(NC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3ccc(C)nc32)c1 nan
20887350 28953 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 0 7 1.3 Cc1nn(CC(=O)N2CCC3(CC2)OCCO3)c(=O)c2cc3ccccc3n12 nan
CHEMBL1380351 28953 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 0 7 1.3 Cc1nn(CC(=O)N2CCC3(CC2)OCCO3)c(=O)c2cc3ccccc3n12 nan
1943710 29112 8 None -6 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 7 5.1 CCCCc1nc2sc3c(SCC(=O)NCc4ccco4)ncnc3c2c2c1CCC2 nan
CHEMBL1381564 29112 8 None -6 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 7 5.1 CCCCc1nc2sc3c(SCC(=O)NCc4ccco4)ncnc3c2c2c1CCC2 nan
2220993 29149 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 4.5 Cc1cc(NC(=O)c2cc(-c3ccccn3)nc3c(Cl)cccc23)no1 nan
CHEMBL1381905 29149 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 4.5 Cc1cc(NC(=O)c2cc(-c3ccccn3)nc3c(Cl)cccc23)no1 nan
2551678 29157 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.3 Cc1[nH]c2ccccc2c1C(=O)CSc1nc2ccccc2c(=O)n1-c1ccccc1F nan
CHEMBL1381998 29157 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.3 Cc1[nH]c2ccccc2c1C(=O)CSc1nc2ccccc2c(=O)n1-c1ccccc1F nan
15997541 29427 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 2 7 3.4 COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cccc(Cl)c3)c3ccccc3c2=O)cc1OC nan
CHEMBL1384419 29427 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 2 7 3.4 COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cccc(Cl)c3)c3ccccc3c2=O)cc1OC nan
2412434 29500 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 2 6 2.0 NS(=O)(=O)c1ccc(NC(=O)CSc2ncnc3ccccc23)cc1 nan
CHEMBL1385049 29500 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 2 6 2.0 NS(=O)(=O)c1ccc(NC(=O)CSc2ncnc3ccccc23)cc1 nan
1490540 29507 16 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 4 1 4 3.9 COc1ccccc1CNc1ncnc2cc(Cl)ccc12 nan
CHEMBL1385084 29507 16 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 4 1 4 3.9 COc1ccccc1CNc1ncnc2cc(Cl)ccc12 nan
1442725 29550 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 4 3.9 CC(C)c1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1385478 29550 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 4 3.9 CC(C)c1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
660521 29629 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 6 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1sc3c(c1C#N)CCC3)CCCCC2 nan
CHEMBL1386214 29629 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 6 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1sc3c(c1C#N)CCC3)CCCCC2 nan
658023 29955 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 2 7 2.7 CCOc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)c(OCC)c1 nan
CHEMBL1388744 29955 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 2 7 2.7 CCOc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)c(OCC)c1 nan
5913531 30008 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 8 1 8 3.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1389094 30008 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 8 1 8 3.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
135749817 30153 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 2 4 4.9 N#C/C(=C(\O)c1cc(Cl)sc1Cl)c1nc2ccccc2[nH]1 nan
CHEMBL1390333 30153 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 2 4 4.9 N#C/C(=C(\O)c1cc(Cl)sc1Cl)c1nc2ccccc2[nH]1 nan
135468428 30331 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 5 2 7 5.1 Cc1cc(-n2c(SCC(=O)Nc3ccc(Br)cc3)nc3nnc(C)c-3c2N)ccc1Cl nan
CHEMBL1391897 30331 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 5 2 7 5.1 Cc1cc(-n2c(SCC(=O)Nc3ccc(Br)cc3)nc3nnc(C)c-3c2N)ccc1Cl nan
5393174 30357 42 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 1 4 3.2 COc1ccc(-c2cc3ccc(O)cc3oc2=O)cc1 nan
CHEMBL1392132 30357 42 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 1 4 3.2 COc1ccc(-c2cc3ccc(O)cc3oc2=O)cc1 nan
738837 30383 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 2 1 2 3.9 Cc1occc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL1392331 30383 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 2 1 2 3.9 Cc1occc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
16194581 30451 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 9 0.9 CC(Sc1nc(-c2ccco2)nc2c1c(=O)n(C)c(=O)n2C)C(=O)O nan
CHEMBL1392938 30451 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 9 0.9 CC(Sc1nc(-c2ccco2)nc2c1c(=O)n(C)c(=O)n2C)C(=O)O nan
16029022 30676 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 2.5 COC(=O)c1ccc(NC(=O)c2cc(S(=O)(=O)N3CCC(C)CC3)cn2C)cc1 nan
CHEMBL1395073 30676 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 2.5 COC(=O)c1ccc(NC(=O)c2cc(S(=O)(=O)N3CCC(C)CC3)cn2C)cc1 nan
16024525 30724 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 5 4.2 Cc1ccc(C(=O)c2cn(CC(=O)NCc3ccccc3Cl)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1395642 30724 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 5 4.2 Cc1ccc(C(=O)c2cn(CC(=O)NCc3ccccc3Cl)c3nc(C)ccc3c2=O)cc1 nan
16009355 30730 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 0 5 5.1 CC(C)c1ccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)cc1 nan
CHEMBL1395773 30730 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 0 5 5.1 CC(C)c1ccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)cc1 nan
16012262 30783 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 1.7 Cc1cccc(NC(=O)CCS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)c1C nan
CHEMBL1396597 30783 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 1.7 Cc1cccc(NC(=O)CCS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)c1C nan
16425494 30802 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.9 CN1CCN(Cc2c(O)ccc3cc(-c4ccccc4)c(=O)oc23)CC1 nan
5522461 30802 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.9 CN1CCN(Cc2c(O)ccc3cc(-c4ccccc4)c(=O)oc23)CC1 nan
CHEMBL1396834 30802 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.9 CN1CCN(Cc2c(O)ccc3cc(-c4ccccc4)c(=O)oc23)CC1 nan
15988387 30806 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 2 4 2.2 COc1cccc(C(=O)NC2=NC(c3ccccc3F)CC(=O)N2)c1 nan
CHEMBL1396902 30806 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 2 4 2.2 COc1cccc(C(=O)NC2=NC(c3ccccc3F)CC(=O)N2)c1 nan
16030463 30826 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 0 4 4.6 CC1CCN(C(=O)CSc2nc3ccccc3nc2Cc2ccccc2)CC1 nan
CHEMBL1397149 30826 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 0 4 4.6 CC1CCN(C(=O)CSc2nc3ccccc3nc2Cc2ccccc2)CC1 nan
16011758 30836 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 8 1 7 2.8 COc1ccc(OC)c(CNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)c1 nan
CHEMBL1397253 30836 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 8 1 7 2.8 COc1ccc(OC)c(CNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)c1 nan
15988254 30894 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 0 7 3.1 COc1cc(OC)cc(-n2c(=O)c3ccccc3n(Cc3ccccc3C#N)c2=O)c1 nan
CHEMBL1398033 30894 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 0 7 3.1 COc1cc(OC)cc(-n2c(=O)c3ccccc3n(Cc3ccccc3C#N)c2=O)c1 nan
5089883 30903 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 0 6 5.9 O=C(CSc1oc(-c2ccc(F)cc2)nc1S(=O)(=O)c1ccccc1)c1ccc(Cl)cc1 nan
CHEMBL1398184 30903 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 0 6 5.9 O=C(CSc1oc(-c2ccc(F)cc2)nc1S(=O)(=O)c1ccccc1)c1ccc(Cl)cc1 nan
16020303 30908 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 2 7 4.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3cccc(F)c3)c2=O)cc1 nan
CHEMBL1398259 30908 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 2 7 4.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3cccc(F)c3)c2=O)cc1 nan
16025636 30914 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 4 1 6 3.9 CN1c2cc(Cl)ccc2-c2nc(SCC(=O)Nc3ccc(F)cc3F)ncc2S1(=O)=O nan
CHEMBL1398402 30914 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 4 1 6 3.9 CN1c2cc(Cl)ccc2-c2nc(SCC(=O)Nc3ccc(F)cc3F)ncc2S1(=O)=O nan
16030333 30923 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 6 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2OC)cc1 nan
CHEMBL1398464 30923 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 6 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2OC)cc1 nan
16022444 30949 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 2 7 4.8 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3nc2s1 nan
CHEMBL1398653 30949 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 2 7 4.8 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3nc2s1 nan
4135187 31002 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 1 6 4.4 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccccc2F)cc1 nan
CHEMBL1399236 31002 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 1 6 4.4 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccccc2F)cc1 nan
2135591 31006 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.7 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(Cl)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
CHEMBL1399275 31006 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.7 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(Cl)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
135546815 31013 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 5 4.0 Cc1ccc(NC(=O)C(C)Sc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)c(C)c1 nan
CHEMBL1399310 31013 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 5 4.0 Cc1ccc(NC(=O)C(C)Sc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)c(C)c1 nan
135513990 31060 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 2 5 4.4 Cc1c(Br)ccc(NC(=O)CSc2nc(O)c3ccccc3n2)c1C nan
CHEMBL1399762 31060 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 2 5 4.4 Cc1c(Br)ccc(NC(=O)CSc2nc(O)c3ccccc3n2)c1C nan
6484563 31136 36 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 0 2 2 3.4 SC1=NC2(CCCCC2)Nc2ccccc21 nan
CHEMBL1400466 31136 36 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 0 2 2 3.4 SC1=NC2(CCCCC2)Nc2ccccc21 nan
16011170 31158 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 4.6 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(Cl)cc1F nan
CHEMBL1400646 31158 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 4.6 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(Cl)cc1F nan
2404851 31184 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 1 7 1.0 O=S(=O)(c1cccc(-c2nnc(S)o2)c1)N1CCOCC1 nan
CHEMBL1400922 31184 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 1 7 1.0 O=S(=O)(c1cccc(-c2nnc(S)o2)c1)N1CCOCC1 nan
659778 31209 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1F nan
CHEMBL1401137 31209 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1F nan
4852309 31224 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 6 1 3 4.5 COc1cc(C(=O)NC(c2ccccc2)c2ccccc2)cc(OC)c1C nan
CHEMBL1401266 31224 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 6 1 3 4.5 COc1cc(C(=O)NC(c2ccccc2)c2ccccc2)cc(OC)c1C nan
1994854 31227 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 8 3.6 CCn1c(SCC(=O)Nc2ccc(C(C)=O)cc2)nc2nc3c(cc2c1=O)COC(C)(C)C3 nan
CHEMBL1401292 31227 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 8 3.6 CCn1c(SCC(=O)Nc2ccc(C(C)=O)cc2)nc2nc3c(cc2c1=O)COC(C)(C)C3 nan
16011439 31527 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 9 1 6 6.3 COc1ccc(Cn2c(SCc3ccc(C(=O)NC(C)c4ccccc4)cc3)nc3cccnc32)cc1 nan
CHEMBL1404015 31527 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 9 1 6 6.3 COc1ccc(Cn2c(SCc3ccc(C(=O)NC(C)c4ccccc4)cc3)nc3cccnc32)cc1 nan
2456084 31532 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 8 2 8 4.0 COc1cc(NC(=O)c2ccco2)c(C(=O)OCC(=O)Nc2ncc(Cl)cc2Cl)cc1OC nan
CHEMBL1404053 31532 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 8 2 8 4.0 COc1cc(NC(=O)c2ccco2)c(C(=O)OCC(=O)Nc2ncc(Cl)cc2Cl)cc1OC nan
2826390 31624 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 5 2.9 COC(=O)c1sccc1NC(=O)C1CC(C)=C(C)CC1C(=O)O nan
CHEMBL1404933 31624 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 5 2.9 COC(=O)c1sccc1NC(=O)C1CC(C)=C(C)CC1C(=O)O nan
16007508 31636 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 3 5.7 CCc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
CHEMBL1405105 31636 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 3 5.7 CCc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
1930124 31727 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 7 5.3 CCCCn1c(NS(=O)(=O)c2ccccc2)c(S(=O)(=O)c2ccc(C)cc2)c2nc3ccccc3nc21 nan
CHEMBL1405964 31727 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 7 5.3 CCCCn1c(NS(=O)(=O)c2ccccc2)c(S(=O)(=O)c2ccc(C)cc2)c2nc3ccccc3nc21 nan
135464462 31882 20 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 6 3.1 CN(C)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
CHEMBL1407344 31882 20 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 6 3.1 CN(C)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
3221573 31913 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 8 3 5 3.0 COCCCN=C(S)NCCNc1nc2c(C)c(C)ccc2cc1C#N nan
CHEMBL1407546 31913 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 8 3 5 3.0 COCCCN=C(S)NCCNc1nc2c(C)c(C)ccc2cc1C#N nan
266900 31927 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 1 1 3 4.3 COC(=O)c1cc(C)nc2c(C)cc3[nH]c4ccccc4c3c12 nan
CHEMBL1407610 31927 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 1 1 3 4.3 COC(=O)c1cc(C)nc2c(C)cc3[nH]c4ccccc4c3c12 nan
16018228 31990 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 5 1.1 CN(C)CCNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
CHEMBL1408060 31990 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 5 1.1 CN(C)CCNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
800213 32022 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 4 4.8 CC(C)(C)c1ccc(-c2nnc(NC(=O)c3ccccc3)s2)cc1 nan
CHEMBL1408281 32022 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 4 4.8 CC(C)(C)c1ccc(-c2nnc(NC(=O)c3ccccc3)s2)cc1 nan
4837904 32086 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 6 4.1 COc1ccc(CCNC(=O)Cc2c(C)c3cc4c(C)coc4cc3oc2=O)cc1OC nan
CHEMBL1408806 32086 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 6 4.1 COc1ccc(CCNC(=O)Cc2c(C)c3cc4c(C)coc4cc3oc2=O)cc1OC nan
915456 32089 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 2 4 4.6 Oc1ccccc1-c1nc(NCc2ccccc2)c2ccccc2n1 nan
CHEMBL1408828 32089 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 2 4 4.6 Oc1ccccc1-c1nc(NCc2ccccc2)c2ccccc2n1 nan
15988127 32219 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 570 6 3 6 7.6 COc1ccccc1NC(=O)c1sc2nc(C)c(C(=O)Nc3ccc(C)cc3C)c(-c3ccccc3Cl)c2c1N nan
CHEMBL1409862 32219 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 570 6 3 6 7.6 COc1ccccc1NC(=O)c1sc2nc(C)c(C(=O)Nc3ccc(C)cc3C)c(-c3ccccc3Cl)c2c1N nan
649505 32222 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 1 7 2.3 O=C(Nc1ccc2c(c1)OCO2)C1CCN(c2ccc(S(=O)(=O)N3CCOCC3)cc2)CC1 nan
CHEMBL1409886 32222 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 1 7 2.3 O=C(Nc1ccc2c(c1)OCO2)C1CCN(c2ccc(S(=O)(=O)N3CCOCC3)cc2)CC1 nan
688670 32240 29 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 0 4 3.5 COc1ccc(-c2cc(=O)c3cc(OC)ccc3o2)cc1 nan
CHEMBL1410006 32240 29 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 0 4 3.5 COc1ccc(-c2cc(=O)c3cc(OC)ccc3o2)cc1 nan
4137223 32348 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 1 5 5.2 Cc1nc(N2CCC(C)CC2)c2c(C)c(C(=O)Nc3ccc(C)c(F)c3)sc2n1 nan
CHEMBL1410912 32348 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 1 5 5.2 Cc1nc(N2CCC(C)CC2)c2c(C)c(C(=O)Nc3ccc(C)c(F)c3)sc2n1 nan
1088392 32539 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 1 7 3.0 COC(=O)c1sc(NC(=O)c2c(OC)cccc2OC)c(C#N)c1C nan
CHEMBL1412474 32539 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 1 7 3.0 COC(=O)c1sc(NC(=O)c2c(OC)cccc2OC)c(C#N)c1C nan
790792 32700 42 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 2 1 3 3.4 CCc1c(C)nc2ccc(OC)cc2c1S nan
CHEMBL1413735 32700 42 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 2 1 3 3.4 CCc1c(C)nc2ccc(OC)cc2c1S nan
16015840 32733 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 4 5.0 Cc1cccc(-c2nc3cc(NC(=O)COc4ccccc4F)ccc3o2)c1 nan
CHEMBL1413987 32733 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 4 5.0 Cc1cccc(-c2nc3cc(NC(=O)COc4ccccc4F)ccc3o2)c1 nan
655034 32829 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 8 2 7 2.4 COc1cc(CC(NC(C)=O)C(=O)NC2CCN(c3nc(C)cc(C)c3C#N)CC2)cc(OC)c1 nan
CHEMBL1414774 32829 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 8 2 7 2.4 COc1cc(CC(NC(C)=O)C(=O)NC2CCN(c3nc(C)cc(C)c3C#N)CC2)cc(OC)c1 nan
16016268 32831 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 0 8 5.0 COc1ccccc1N1CCN(c2ccc(-c3nc(-c4ccccc4C)no3)cc2[N+](=O)[O-])CC1 nan
CHEMBL1414801 32831 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 0 8 5.0 COc1ccccc1N1CCN(c2ccc(-c3nc(-c4ccccc4C)no3)cc2[N+](=O)[O-])CC1 nan
2156145 32928 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 2 9 4.3 COc1ccc(-n2c(SCC(=O)Nc3cc(C)on3)nc3c4ccccc4nc-3c2O)cc1 nan
CHEMBL1415709 32928 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 2 9 4.3 COc1ccc(-n2c(SCC(=O)Nc3cc(C)on3)nc3c4ccccc4nc-3c2O)cc1 nan
7190669 32989 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1 nan
CHEMBL1416264 32989 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1 nan
16012962 33004 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 0 6 3.9 Fc1cccc(-n2ncc3c2ncn2nc(-c4ccccc4Cl)nc32)c1 nan
CHEMBL1416375 33004 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 0 6 3.9 Fc1cccc(-n2ncc3c2ncn2nc(-c4ccccc4Cl)nc32)c1 nan
4808145 33161 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 7 1.3 Cn1c(=O)c2c(ncn2CCOc2ccc(Br)cc2)n(C)c1=O nan
CHEMBL1417778 33161 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 7 1.3 Cn1c(=O)c2c(ncn2CCOc2ccc(Br)cc2)n(C)c1=O nan
16009664 33240 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
CHEMBL1418446 33240 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
4625060 33311 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 3 2 4 2.2 O=C(CC1N=C2c3ccccc3NC(=S)N2C1=O)NC1CCCCC1 nan
CHEMBL1419028 33311 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 3 2 4 2.2 O=C(CC1N=C2c3ccccc3NC(=S)N2C1=O)NC1CCCCC1 nan
665236 33357 8 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 7 4.4 CCc1nc(SCC(=O)Nc2ccc3c(c2)OCCO3)c2oc3ccccc3c2n1 nan
CHEMBL1419387 33357 8 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 7 4.4 CCc1nc(SCC(=O)Nc2ccc3c(c2)OCCO3)c2oc3ccccc3c2n1 nan
20927027 33374 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 7 2.0 O=S(=O)(c1ccc(-c2ccc(O)nn2)o1)N1CCN(c2ccccc2)CC1 nan
CHEMBL1419593 33374 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 7 2.0 O=S(=O)(c1ccc(-c2ccc(O)nn2)o1)N1CCN(c2ccccc2)CC1 nan
16024782 33533 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 5 3.9 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4F)CC3)ccc2c1)N1CCCCC1 nan
CHEMBL1420848 33533 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 5 3.9 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4F)CC3)ccc2c1)N1CCCCC1 nan
3185701 33557 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 541 10 3 8 3.0 CCOc1ccc(C(C(=O)NCC2CCCO2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2F)cc1 nan
CHEMBL1421091 33557 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 541 10 3 8 3.0 CCOc1ccc(C(C(=O)NCC2CCCO2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2F)cc1 nan
1078539 33810 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 0 7 2.5 Cc1cccc(-n2ncc3c(N4CCC5(CC4)OCCO5)ncnc32)c1 nan
CHEMBL1423202 33810 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 0 7 2.5 Cc1cccc(-n2ncc3c(N4CCC5(CC4)OCCO5)ncnc32)c1 nan
993322 33849 15 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 4.2 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)Nc3cc(C)on3)n2)cc1 nan
CHEMBL1423477 33849 15 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 4.2 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)Nc3cc(C)on3)n2)cc1 nan
16194711 34059 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 9 1.5 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(CCNC(=O)c4ccccc4)n3n2)CC1 nan
CHEMBL1425185 34059 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 9 1.5 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(CCNC(=O)c4ccccc4)n3n2)CC1 nan
661193 34243 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 5 1 7 1.9 Cc1cccc(-n2ncc3c(NCCN4CCOCC4)ncnc32)c1 nan
CHEMBL1426726 34243 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 5 1 7 1.9 Cc1cccc(-n2ncc3c(NCCN4CCOCC4)ncnc32)c1 nan
2999700 34388 3 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 5 4.6 Cn1c(/C(C#N)=C(\O)COc2ccc3ccccc3c2)nc2ccccc21 nan
CHEMBL1428087 34388 3 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 5 4.6 Cn1c(/C(C#N)=C(\O)COc2ccc3ccccc3c2)nc2ccccc21 nan
1371384 34511 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 225 1 1 4 2.7 Cc1ccc(/C=C2/SC(=O)NC2=S)o1 nan
CHEMBL1429158 34511 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 225 1 1 4 2.7 Cc1ccc(/C=C2/SC(=O)NC2=S)o1 nan
2815019 34808 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 8 0.7 Cn1c(=O)c2c(nc(Sc3ccccc3N)n2C)n(C)c1=O nan
CHEMBL1431497 34808 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 8 0.7 Cn1c(=O)c2c(nc(Sc3ccccc3N)n2C)n(C)c1=O nan
2114663 34851 6 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 5 5.3 Cc1onc(-c2ccccc2)c1C(=O)Nc1nc(-c2cc(F)ccc2F)cs1 nan
CHEMBL1431887 34851 6 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 5 5.3 Cc1onc(-c2ccccc2)c1C(=O)Nc1nc(-c2cc(F)ccc2F)cs1 nan
650995 34954 14 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 6 4.2 Cc1nonc1NC(=O)CSc1nc2cc(Cl)ccc2c2c1CCCC2 nan
CHEMBL1432773 34954 14 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 6 4.2 Cc1nonc1NC(=O)CSc1nc2cc(Cl)ccc2c2c1CCCC2 nan
15989049 35044 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 529 8 1 8 3.9 O=C(CCCn1c(=O)c2sccc2n(Cc2ccc(F)cc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1433448 35044 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 529 8 1 8 3.9 O=C(CCCn1c(=O)c2sccc2n(Cc2ccc(F)cc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
16009658 35058 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)cc1)c1cccc(F)c1 nan
CHEMBL1433649 35058 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)cc1)c1cccc(F)c1 nan
16030989 35064 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 0 7 4.3 COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
CHEMBL1433722 35064 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 0 7 4.3 COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
15990910 35077 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 2 4 5.8 CSc1cccc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
CHEMBL1433922 35077 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 2 4 5.8 CSc1cccc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
16008787 35118 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 4.3 COc1ccccc1CNC(=O)c1cc2c(=O)oc3ccc(C)cc3c2s1 nan
CHEMBL1434647 35118 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 4.3 COc1ccccc1CNC(=O)c1cc2c(=O)oc3ccc(C)cc3c2s1 nan
16022785 35119 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 6 1 8 3.5 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3nc(-c4ccccc4)no3)c(=O)c3ccccc32)c(C)c1 nan
CHEMBL1434648 35119 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 6 1 8 3.5 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3nc(-c4ccccc4)no3)c(=O)c3ccccc32)c(C)c1 nan
24819144 35124 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 6 6.0 COC(=O)c1ccc(/C=C/c2c(-c3ccsc3)oc3ccc(N4CCOCC4)cc23)cc1 nan
CHEMBL1434681 35124 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 6 6.0 COC(=O)c1ccc(/C=C/c2c(-c3ccsc3)oc3ccc(N4CCOCC4)cc23)cc1 nan
135546816 35130 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 2 6 3.8 CCOc1ccccc1NC(=O)C(C)Sc1nc(-c2ccccc2)c(C#N)c(=O)[nH]1 nan
CHEMBL1434743 35130 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 2 6 3.8 CCOc1ccccc1NC(=O)C(C)Sc1nc(-c2ccccc2)c(C#N)c(=O)[nH]1 nan
16024519 35148 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 7 3.7 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCCO4)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1435013 35148 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 7 3.7 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCCO4)c3nc(C)ccc3c2=O)cc1 nan
16018510 35152 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 5 5.3 COc1cccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCCCC4)ccc23)c1 nan
CHEMBL1435044 35152 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 5 5.3 COc1cccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCCCC4)ccc23)c1 nan
15988487 35162 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 1 4 4.3 CC1(C)CC(=O)c2cc(-c3nc(-c4ccccc4)cs3)c(=O)[nH]c2C1 nan
CHEMBL1435109 35162 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 1 4 4.3 CC1(C)CC(=O)c2cc(-c3nc(-c4ccccc4)cs3)c(=O)[nH]c2C1 nan
6225711 35227 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 4 3.6 Cc1cc(O)c2c(C)c(CC(=O)NCc3ccccc3Cl)c(=O)oc2c1 nan
CHEMBL1435970 35227 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 4 3.6 Cc1cc(O)c2c(C)c(CC(=O)NCc3ccccc3Cl)c(=O)oc2c1 nan
15987771 35231 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 0 5 3.5 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)c21 nan
CHEMBL1436008 35231 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 0 5 3.5 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)c21 nan
5059361 35250 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 0 6 4.7 Cc1cccc(-c2nc3ccccc3n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c23)c1 nan
CHEMBL1436184 35250 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 0 6 4.7 Cc1cccc(-c2nc3ccccc3n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c23)c1 nan
4230972 35322 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 543 9 2 7 4.8 CC(C)c1ccc(NC(=O)CSC2=Nc3ccccc3C3=NC(CCC(=O)NCc4ccco4)C(=O)N23)cc1 nan
CHEMBL1437178 35322 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 543 9 2 7 4.8 CC(C)c1ccc(NC(=O)CSC2=Nc3ccccc3C3=NC(CCC(=O)NCc4ccco4)C(=O)N23)cc1 nan
16007712 35323 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 0 6 3.5 CCN(CC)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)N1CCN(c3cc(Cl)ccc3C)CC1)cn2C nan
CHEMBL1437207 35323 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 0 6 3.5 CCN(CC)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)N1CCN(c3cc(Cl)ccc3C)CC1)cn2C nan
15988469 35404 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 6 1 6 4.8 COc1ccc(NC(=O)C2CCN(c3ccc(Sc4ccc(C)cc4)nn3)CC2)cc1 nan
CHEMBL1438027 35404 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 6 1 6 4.8 COc1ccc(NC(=O)C2CCN(c3ccc(Sc4ccc(C)cc4)nn3)CC2)cc1 nan
3230795 35418 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 0 6 4.6 CN(C(=O)CSC1=NC2C(N=N1)c1cc(Br)ccc1N2C)C1CCCCC1 nan
CHEMBL1438136 35418 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 0 6 4.6 CN(C(=O)CSC1=NC2C(N=N1)c1cc(Br)ccc1N2C)C1CCCCC1 nan
16017737 35629 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 5 1.9 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccc(F)cc1 nan
CHEMBL1440044 35629 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 5 1.9 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccc(F)cc1 nan
16024943 35674 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 4.0 CC(=O)c1ccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)cc1 nan
CHEMBL1440442 35674 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 4.0 CC(=O)c1ccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)cc1 nan
16195917 35747 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 8 0.2 Cn1c(N)c(C(=O)COC(=O)CC2CC3CCC2C3)c(=O)n(C)c1=O nan
CHEMBL1441131 35747 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 8 0.2 Cn1c(N)c(C(=O)COC(=O)CC2CC3CCC2C3)c(=O)n(C)c1=O nan
16009208 35843 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 6 3.2 CCOc1ccc(CNC(=O)Cn2ncc3c(=O)oc4ccc(C)cc4c32)cc1 nan
CHEMBL1441997 35843 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 6 3.2 CCOc1ccc(CNC(=O)Cn2ncc3c(=O)oc4ccc(C)cc4c32)cc1 nan
2980137 36055 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 7 2.7 COc1ccc(-n2c(SC(C)C(=O)N3CCOCC3)nc3ccccc3c2=O)cc1 nan
CHEMBL1443960 36055 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 7 2.7 COc1ccc(-n2c(SC(C)C(=O)N3CCOCC3)nc3ccccc3c2=O)cc1 nan
2421482 36122 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 9 3.0 CCOC(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 nan
CHEMBL1444560 36122 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 9 3.0 CCOC(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 nan
2136705 36167 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 1 7 3.8 COc1cc2c(=O)c(S(=O)(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3C)c2cc1OC nan
CHEMBL1444994 36167 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 1 7 3.8 COc1cc2c(=O)c(S(=O)(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3C)c2cc1OC nan
4154281 36189 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 5 5.3 O=C(CSc1ncnc2c1sc1ccccc12)Nc1ccc(Br)cc1 nan
CHEMBL1445182 36189 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 5 5.3 O=C(CSc1ncnc2c1sc1ccccc12)Nc1ccc(Br)cc1 nan
738863 36216 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 4 3.6 O=C(Nc1nc(=O)c2ccccc2s1)c1ccc(Cl)cc1 nan
CHEMBL1445436 36216 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 4 3.6 O=C(Nc1nc(=O)c2ccccc2s1)c1ccc(Cl)cc1 nan
3151463 36577 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 7 1.8 COCCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1448581 36577 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 7 1.8 COCCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3ccccc3nc21 nan
20903711 36649 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 7 1.1 COCCNC(=O)CCc1nnc2ccc(N3CCC(C)CC3)nn12 nan
CHEMBL1449064 36649 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 7 1.1 COCCNC(=O)CCc1nnc2ccc(N3CCC(C)CC3)nn12 nan
9550466 36661 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 6 1 4 5.5 Cc1ccc(-n2nc(C)c3c(C)c(CCC(=O)NC(C)c4ccccc4)c(C)nc32)cc1 nan
CHEMBL1449158 36661 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 6 1 4 5.5 Cc1ccc(-n2nc(C)c3c(C)c(CCC(=O)NC(C)c4ccccc4)c(C)nc32)cc1 nan
1440341 36667 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 3 4.8 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1ccccc1)CCC3 nan
CHEMBL1449215 36667 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 3 4.8 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1ccccc1)CCC3 nan
1034641 36785 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 1 5 3.8 Cc1ccc(-n2c(N)c(C#N)c(-c3ccc(Cl)cc3)c(C#N)c2=O)cc1 nan
CHEMBL1450150 36785 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 1 5 3.8 Cc1ccc(-n2c(N)c(C#N)c(-c3ccc(Cl)cc3)c(C#N)c2=O)cc1 nan
16009195 36805 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 5 3.5 CCN(Cc1ccccc1)C(=O)Cn1ncc2c(=O)oc3ccc(C)cc3c21 nan
CHEMBL1450283 36805 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 5 3.5 CCN(Cc1ccccc1)C(=O)Cn1ncc2c(=O)oc3ccc(C)cc3c21 nan
1341628 36867 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 4 5.8 CC(=O)c1ccc(NC(=O)c2cn(-c3ccccc3)nc2-c2ccc(Br)cc2)cc1 nan
CHEMBL1450882 36867 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 4 5.8 CC(=O)c1ccc(NC(=O)c2cn(-c3ccccc3)nc2-c2ccc(Br)cc2)cc1 nan
16019140 37280 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 8 3.9 Cc1cc(C)cc(NC(=O)Cn2c(=O)n(Cc3ccc4c(c3)OCO4)c(=O)c3oc4ccccc4c32)c1 nan
CHEMBL1454100 37280 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 8 3.9 Cc1cc(C)cc(NC(=O)Cn2c(=O)n(Cc3ccc4c(c3)OCO4)c(=O)c3oc4ccccc4c32)c1 nan
16009221 37324 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 1 7 4.6 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(CC)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
CHEMBL1454484 37324 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 1 7 4.6 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(CC)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
16026522 37352 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 5 4.3 CCOC(=O)c1sc2cccc(F)c2c1S(=O)(=O)NCc1ccccc1Cl nan
CHEMBL1454707 37352 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 5 4.3 CCOC(=O)c1sc2cccc(F)c2c1S(=O)(=O)NCc1ccccc1Cl nan
6011252 37395 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 12 1 8 4.5 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCN2CCOCC2)cc1OC nan
CHEMBL1455062 37395 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 12 1 8 4.5 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCN2CCOCC2)cc1OC nan
16026066 37411 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 4 1 4 4.7 CCc1ccccc1NC(=O)C1CCN(C2=NS(=O)(=O)C(c3ccc(C)c(C)c3)=C2C)CC1 nan
CHEMBL1455235 37411 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 4 1 4 4.7 CCc1ccccc1NC(=O)C1CCN(C2=NS(=O)(=O)C(c3ccc(C)c(C)c3)=C2C)CC1 nan
24819160 37520 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 0 6 5.9 COC(=O)c1ccc(/C=C/c2c(-c3ccc(OC)cc3)oc3ccc(N4CCOCC4)cc23)cc1 nan
CHEMBL1456226 37520 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 0 6 5.9 COC(=O)c1ccc(/C=C/c2c(-c3ccc(OC)cc3)oc3ccc(N4CCOCC4)cc23)cc1 nan
135520065 37715 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 8 2 8 2.5 COC(=O)C(CC(C)C)NC(=O)CSc1nc(O)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1457936 37715 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 8 2 8 2.5 COC(=O)C(CC(C)C)NC(=O)CSc1nc(O)c(C#N)c(-c2ccccc2)n1 nan
2125831 37762 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 2 2 3.9 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(Cl)cc2F)c1C nan
CHEMBL1458351 37762 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 2 2 3.9 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(Cl)cc2F)c1C nan
1110886 38032 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 3 5 5.4 CC(=O)Nc1ccc(-c2cc(-c3ccc(NC(C)=O)cc3)nc(-c3ccc(NC(C)=O)cc3)n2)cc1 nan
CHEMBL1460618 38032 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 3 5 5.4 CC(=O)Nc1ccc(-c2cc(-c3ccc(NC(C)=O)cc3)nc(-c3ccc(NC(C)=O)cc3)n2)cc1 nan
17255621 38088 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 2 6 3.7 CCOc1ccc(NC(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1 nan
CHEMBL1461095 38088 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 2 6 3.7 CCOc1ccc(NC(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1 nan
4437250 38091 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 6 2 2 4.2 CCN=C(S)N(CCc1c(C)[nH]c2ccccc12)Cc1cccnc1 nan
CHEMBL1461107 38091 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 6 2 2 4.2 CCN=C(S)N(CCc1c(C)[nH]c2ccccc12)Cc1cccnc1 nan
2784799 38217 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 1 1 4 2.5 O=C1C([N+](=O)[O-])=C(O)c2cccc3cccc1c23 nan
CHEMBL1462267 38217 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 1 1 4 2.5 O=C1C([N+](=O)[O-])=C(O)c2cccc3cccc1c23 nan
1442463 38384 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 5 4.0 CC(C)(C)c1nc(SCC(=O)N2CC(=O)Nc3ccccc32)c2ccccc2n1 nan
CHEMBL1463696 38384 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 5 4.0 CC(C)(C)c1nc(SCC(=O)N2CC(=O)Nc3ccccc32)c2ccccc2n1 nan
664194 38412 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 0 7 2.7 c1ccc(-n2ncc3c2ncn2nc(-c4ccco4)nc32)cc1 nan
CHEMBL1463869 38412 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 0 7 2.7 c1ccc(-n2ncc3c2ncn2nc(-c4ccco4)nc32)cc1 nan
2370579 38477 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 8 -0.4 Cn1c(N)c(C(=O)COC(=O)C2CCCC2)c(=O)n(C)c1=O nan
CHEMBL1464368 38477 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 8 -0.4 Cn1c(N)c(C(=O)COC(=O)C2CCCC2)c(=O)n(C)c1=O nan
4230513 38519 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 9 0.6 CC(C)Cn1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1464655 38519 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 9 0.6 CC(C)Cn1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
1214727 38655 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 1 5 4.2 Cc1c(-c2ccc(Cl)cc2)oc(=O)c2c(N)n(-c3ccccc3)nc12 nan
CHEMBL1465659 38655 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 1 5 4.2 Cc1c(-c2ccc(Cl)cc2)oc(=O)c2c(N)n(-c3ccccc3)nc12 nan
4225516 38760 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 5 3.5 O=C(O)c1cccnc1SCc1cn2cc(Br)ccc2n1 nan
CHEMBL1466534 38760 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 5 3.5 O=C(O)c1cccnc1SCc1cn2cc(Br)ccc2n1 nan
16020097 38871 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 9 1 7 3.3 CCCCN(C)CCNC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1467366 38871 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 9 1 7 3.3 CCCCN(C)CCNC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c1c1ccccc1n2C nan
3137696 38887 25 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 0 7 -0.2 COCCn1c(Br)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1467508 38887 25 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 0 7 -0.2 COCCn1c(Br)nc2c1c(=O)n(C)c(=O)n2C nan
2396532 38986 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 2 9 -0.1 CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
CHEMBL1468416 38986 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 2 9 -0.1 CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
4994172 39112 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 2 5 4.0 Nc1cc(C(=O)Nc2ccc(Cl)cc2)ccc1N1CC2CC(C1)c1cccc(=O)n1C2 nan
CHEMBL1469442 39112 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 2 5 4.0 Nc1cc(C(=O)Nc2ccc(Cl)cc2)ccc1N1CC2CC(C1)c1cccc(=O)n1C2 nan
2517516 39264 8 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 2.7 CC(C)COc1ccc(C(=O)N2C(=O)c3ccc(N)cc3C2=O)cc1 nan
CHEMBL1470757 39264 8 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 2.7 CC(C)COc1ccc(C(=O)N2C(=O)c3ccc(N)cc3C2=O)cc1 nan
4968659 39393 6 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 9 2 6 6.1 CCc1ccc(-c2nc(NC(=O)c3ccc(OCC(=O)Nc4ccc(F)cc4)c(OC)c3)sc2C)cc1 nan
CHEMBL1471857 39393 6 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 9 2 6 6.1 CCc1ccc(-c2nc(NC(=O)c3ccc(OCC(=O)Nc4ccc(F)cc4)c(OC)c3)sc2C)cc1 nan
16032187 39503 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 8 2.7 Cc1cc(NC(=O)CSc2ncc(C(=O)Nc3ccc(Cl)cc3)c(=O)n2C)no1 nan
CHEMBL1472946 39503 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 8 2.7 Cc1cc(NC(=O)CSc2ncc(C(=O)Nc3ccc(Cl)cc3)c(=O)n2C)no1 nan
16416626 39546 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 6 2.3 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccc1 nan
7205030 39546 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 6 2.3 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccc1 nan
CHEMBL1473511 39546 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 6 2.3 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccc1 nan
16022561 39548 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 2 7 5.0 Cc1c(Cl)cccc1Nc1nn2c(=O)c3ccc(C(=O)NCCc4ccccc4)cc3nc2s1 nan
CHEMBL1473551 39548 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 2 7 5.0 Cc1c(Cl)cccc1Nc1nn2c(=O)c3ccc(C(=O)NCCc4ccccc4)cc3nc2s1 nan
16025981 39584 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 5 4.3 O=c1cc2nc(-c3ccccc3F)nc(SCc3ccc(Br)cc3)n2[nH]1 nan
CHEMBL1474099 39584 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 5 4.3 O=c1cc2nc(-c3ccccc3F)nc(SCc3ccc(Br)cc3)n2[nH]1 nan
5302625 39615 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 2 5 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2OC)cc1 nan
CHEMBL1474507 39615 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 2 5 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2OC)cc1 nan
20893081 39653 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 8 2.1 COc1ccc(NC(=O)C2CCCN2c2nn3c(=O)cc(C)nc3s2)cc1 nan
CHEMBL1475089 39653 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 8 2.1 COc1ccc(NC(=O)C2CCCN2c2nn3c(=O)cc(C)nc3s2)cc1 nan
15988958 39671 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 2 7 4.5 Cc1ccc(CNC(=O)CCCCCn2c(=O)c3sccc3n(CC(=O)Nc3ccc(C)c(F)c3)c2=O)cc1 nan
CHEMBL1475354 39671 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 2 7 4.5 Cc1ccc(CNC(=O)CCCCCn2c(=O)c3sccc3n(CC(=O)Nc3ccc(C)c(F)c3)c2=O)cc1 nan
16020297 39692 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 557 7 1 6 5.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(Cc3ccc(F)cc3Cl)c2=O)cc1 nan
CHEMBL1475582 39692 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 557 7 1 6 5.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(Cc3ccc(F)cc3Cl)c2=O)cc1 nan
16015655 39745 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 6 5.6 COc1ccccc1C(=O)Nc1ccc2nc(SCC(=O)N3CCCc4ccccc43)sc2c1 nan
CHEMBL1476387 39745 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 6 5.6 COc1ccccc1C(=O)Nc1ccc2nc(SCC(=O)N3CCCc4ccccc43)sc2c1 nan
15988828 39778 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 4.0 O=C(Nc1cccc(Cl)c1)c1cc(-c2ccc3c(c2)OCO3)on1 nan
CHEMBL1476787 39778 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 4.0 O=C(Nc1cccc(Cl)c1)c1cc(-c2ccc3c(c2)OCO3)on1 nan
15988909 39819 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 0 7 3.4 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3ccc(F)cc3)c2=O)c1 nan
CHEMBL1477251 39819 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 0 7 3.4 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3ccc(F)cc3)c2=O)c1 nan
16027484 39835 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 8 3.8 O=C(Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1)c1cccc(F)c1 nan
CHEMBL1477385 39835 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 8 3.8 O=C(Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1)c1cccc(F)c1 nan
16009837 39843 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 7 4.7 COc1cccc(NC(=O)Cn2c(=O)n(-c3ccc(Cl)cc3)c(=O)c3sc4ccccc4c32)c1 nan
CHEMBL1477435 39843 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 7 4.7 COc1cccc(NC(=O)Cn2c(=O)n(-c3ccc(Cl)cc3)c(=O)c3sc4ccccc4c32)c1 nan
663717 39898 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 7 4.0 CCOCCCn1cnc2c(c1=O)c1nc3ccccc3nc1n2-c1ccc(C)cc1 nan
CHEMBL1477914 39898 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 7 4.0 CCOCCCn1cnc2c(c1=O)c1nc3ccccc3nc1n2-c1ccc(C)cc1 nan
16018985 39913 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 5 4.3 O=C(NCCc1ccc(Cl)cc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1478117 39913 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 5 4.3 O=C(NCCc1ccc(Cl)cc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
15988423 39993 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 4 2.8 COc1ccccc1NC(=O)c1cc2c([nH]c1=O)CC(C)(C)CC2=O nan
CHEMBL1478841 39993 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 4 2.8 COc1ccccc1NC(=O)c1cc2c([nH]c1=O)CC(C)(C)CC2=O nan
24819115 40044 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 5 6 2.9 Nc1c(Cl)cc(-c2nc3cc(C(=O)NCCO)ccc3c(O)c2O)cc1Cl nan
CHEMBL1479302 40044 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 5 6 2.9 Nc1c(Cl)cc(-c2nc3cc(C(=O)NCCO)ccc3c(O)c2O)cc1Cl nan
2511800 40068 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 2 5 4.0 CCOc1ncccc1C(=O)Nc1ccc(C(=O)Nc2ccc(OC)cc2)cc1 nan
CHEMBL1479469 40068 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 2 5 4.0 CCOc1ncccc1C(=O)Nc1ccc(C(=O)Nc2ccc(OC)cc2)cc1 nan
3352626 40211 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 11 1 6 5.3 CCCC[S+]([O-])CC(O)CSc1nc(-c2ccc(OC)cc2)cc(-c2ccccc2)c1C#N nan
CHEMBL1480619 40211 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 11 1 6 5.3 CCCC[S+]([O-])CC(O)CSc1nc(-c2ccc(OC)cc2)cc(-c2ccccc2)c1C#N nan
20957489 40357 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)n2n1 nan
CHEMBL1481894 40357 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)n2n1 nan
16033868 40362 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 2 9 4.0 COc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4cccs4)cc3nc2s1 nan
CHEMBL1481939 40362 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 2 9 4.0 COc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4cccs4)cc3nc2s1 nan
5297519 40412 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 5 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1ccc(C(F)(F)F)cc1)C1CCN2CC1 nan
CHEMBL1482409 40412 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 5 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1ccc(C(F)(F)F)cc1)C1CCN2CC1 nan
16030774 40474 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 9 1.2 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3F)nc2n(C)c1=O nan
CHEMBL1482929 40474 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 9 1.2 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3F)nc2n(C)c1=O nan
16017755 40553 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 5 2.0 O=C(Cn1ccn(-c2cccc(Cl)c2)c(=O)c1=O)NCCc1ccccc1 nan
CHEMBL1483603 40553 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 5 2.0 O=C(Cn1ccn(-c2cccc(Cl)c2)c(=O)c1=O)NCCc1ccccc1 nan
16015423 40567 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 1 6 6.2 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccccc3F)cc2s1 nan
CHEMBL1483703 40567 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 1 6 6.2 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccccc3F)cc2s1 nan
1477383 40847 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 3 3 2.7 O=C(NC(=S)Nc1cccc2[nH]ncc12)c1ccccc1 nan
CHEMBL1486203 40847 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 3 3 2.7 O=C(NC(=S)Nc1cccc2[nH]ncc12)c1ccccc1 nan
16009820 40880 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 5 4.5 CC(C)Nc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
CHEMBL1486479 40880 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 5 4.5 CC(C)Nc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
646986 40965 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 1 5 3.5 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccnc1)c1ccco1 nan
CHEMBL1487207 40965 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 1 5 3.5 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccnc1)c1ccco1 nan
15996976 41064 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 2 4 3.0 CC1CCN(S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccc(F)cc4)c(=O)c3c2)CC1 nan
CHEMBL1487954 41064 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 2 4 3.0 CC1CCN(S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccc(F)cc4)c(=O)c3c2)CC1 nan
24260 41223 89 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 1 3 3 2.4 Nc1ccc(-c2nc3cc(N)ccc3[nH]2)cc1 nan
CHEMBL1489074 41223 89 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 1 3 3 2.4 Nc1ccc(-c2nc3cc(N)ccc3[nH]2)cc1 nan
3144653 41230 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 5 3.8 CCCNC(=O)CSc1nc(-c2ccc(OC)cc2)cc(C(F)(F)F)n1 nan
CHEMBL1489101 41230 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 5 3.8 CCCNC(=O)CSc1nc(-c2ccc(OC)cc2)cc(C(F)(F)F)n1 nan
5079958 41231 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 3 4.6 CCc1ccc(Sc2cc(C(=O)O)c3ccccc3n2)cc1 nan
CHEMBL1489124 41231 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 3 4.6 CCc1ccc(Sc2cc(C(=O)O)c3ccccc3n2)cc1 nan
16001343 41273 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 7 1 7 3.3 COc1cc(NC(=O)CSc2cc(=O)n(C)c3ccccc23)cc(OC)c1OC nan
CHEMBL1489463 41273 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 7 1 7 3.3 COc1cc(NC(=O)CSc2cc(=O)n(C)c3ccccc23)cc(OC)c1OC nan
1327191 41300 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 2 6 4.8 COc1ccc(OC)c(Nc2nc(-c3ccccc3O)nc3ccccc23)c1 nan
CHEMBL1489694 41300 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 2 6 4.8 COc1ccc(OC)c(Nc2nc(-c3ccccc3O)nc3ccccc23)c1 nan
3151460 41321 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 7 2.2 COCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1489888 41321 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 7 2.2 COCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
4282213 41385 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.8 CC1CCCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)C1 nan
CHEMBL1490341 41385 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.8 CC1CCCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)C1 nan
28358990 41592 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 6 5.1 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Cl)c(C(F)(F)F)oc23)CC1 nan
5451590 41592 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 6 5.1 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Cl)c(C(F)(F)F)oc23)CC1 nan
CHEMBL1491733 41592 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 6 5.1 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Cl)c(C(F)(F)F)oc23)CC1 nan
16025965 41672 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 10 1.4 CCOC(=O)c1cccc(NC(=O)c2cnc3sc(N4CCOCC4)nn3c2=O)c1 nan
CHEMBL1492345 41672 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 10 1.4 CCOC(=O)c1cccc(NC(=O)c2cnc3sc(N4CCOCC4)nn3c2=O)c1 nan
6157069 41739 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1OC nan
CHEMBL1492815 41739 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1OC nan
12005902 41776 10 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 1 10 4.1 COc1ccc(-c2nnc3ccc(SCC(=O)Nc4nc5ccccc5s4)nn23)cc1OC nan
CHEMBL1493244 41776 10 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 1 10 4.1 COc1ccc(-c2nnc3ccc(SCC(=O)Nc4nc5ccccc5s4)nn23)cc1OC nan
16022789 41787 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 6 1 8 3.5 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3nc(-c4ccccc4)no3)c(=O)c3ccccc32)cc1C nan
CHEMBL1493335 41787 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 6 1 8 3.5 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3nc(-c4ccccc4)no3)c(=O)c3ccccc32)cc1C nan
2096572 41852 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 5 5.0 COc1ccc2c(C)cc(SCC(=O)Nc3ncc(Cl)cc3Cl)nc2c1 nan
CHEMBL1493965 41852 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 5 5.0 COc1ccc2c(C)cc(SCC(=O)Nc3ncc(Cl)cc3Cl)nc2c1 nan
16026311 42000 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 4.5 CCc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4ccc(F)cc4C)c32)cc1 nan
CHEMBL1495516 42000 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 4.5 CCc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4ccc(F)cc4C)c32)cc1 nan
4258482 42124 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 0 5 5.6 Cc1cccc(Cc2c(C)nc3nc(SCc4ccccc4Cl)nn3c2C)c1 nan
CHEMBL1496672 42124 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 0 5 5.6 Cc1cccc(Cc2c(C)nc3nc(SCc4ccccc4Cl)nn3c2C)c1 nan
17583888 42160 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 6 1 5 3.5 CCCc1cc(=O)oc2c(C)c(OCC(=O)Nc3ccccn3)ccc12 nan
CHEMBL1496919 42160 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 6 1 5 3.5 CCCc1cc(=O)oc2c(C)c(OCC(=O)Nc3ccccn3)ccc12 nan
3260315 42230 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 9 0.6 Cc1ccc(Cl)cc1NC(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1497548 42230 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 9 0.6 Cc1ccc(Cl)cc1NC(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
1488204 42520 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 4 0 5 5.3 O=S(=O)(c1ccccc1)c1cnc(-c2cccnc2)nc1-c1ccc(Cl)c(Cl)c1 nan
CHEMBL1500120 42520 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 4 0 5 5.3 O=S(=O)(c1ccccc1)c1cnc(-c2cccnc2)nc1-c1ccc(Cl)c(Cl)c1 nan
5309910 43051 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 2 7 2.2 CCOc1ccc(Cn2nnc(C(=O)NCc3ccc(OC)cc3)c2N)cc1 nan
CHEMBL1504868 43051 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 2 7 2.2 CCOc1ccc(Cn2nnc(C(=O)NCc3ccc(OC)cc3)c2N)cc1 nan
135422740 43099 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 5 1 7 4.8 Nc1c2cnnc-2nc(SCC(=O)c2ccc(Br)cc2)n1-c1ccc(Br)cc1 nan
CHEMBL1505277 43099 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 5 1 7 4.8 Nc1c2cnnc-2nc(SCC(=O)c2ccc(Br)cc2)n1-c1ccc(Br)cc1 nan
4975174 43650 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 0 7 1.2 COCCCn1c(C(=O)N2CCOCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1510079 43650 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 0 7 1.2 COCCCn1c(C(=O)N2CCOCC2)cc2c(=O)n3ccccc3nc21 nan
6236457 43674 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 523 7 1 10 4.0 COc1cc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nnc(C)s2)cc(OC)c1OC nan
CHEMBL1510318 43674 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 523 7 1 10 4.0 COc1cc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nnc(C)s2)cc(OC)c1OC nan
135399378 43702 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 2 7 2.5 CCOc1ccc(N2CC(=O)C(c3nc(O)c4ccccc4n3)=C2N)cc1 nan
CHEMBL1510511 43702 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 2 7 2.5 CCOc1ccc(N2CC(=O)C(c3nc(O)c4ccccc4n3)=C2N)cc1 nan
16026527 43883 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 6 3.7 COc1ccc(CNC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)cc1 nan
CHEMBL1512255 43883 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 6 3.7 COc1ccc(CNC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)cc1 nan
16012611 43902 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 4 4.8 Cc1nc2c(c(C)nn2C(C)(C)C)c(C)c1CCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1512506 43902 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 4 4.8 Cc1nc2c(c(C)nn2C(C)(C)C)c(C)c1CCC(=O)Nc1ccc(F)cc1 nan
4405319 43933 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4cccc5ccccc45)nc3c2)cc1 nan
CHEMBL1512869 43933 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4cccc5ccccc45)nc3c2)cc1 nan
16024551 43960 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 7 4.4 CCOC(=O)c1ccc(NC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)cc1 nan
CHEMBL1513333 43960 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 7 4.4 CCOC(=O)c1ccc(NC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)cc1 nan
135416471 43967 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 Cc1ccc(-c2nc3c4ccccc4[nH]c(=O)n3n2)cc1 nan
CHEMBL1513443 43967 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 Cc1ccc(-c2nc3c4ccccc4[nH]c(=O)n3n2)cc1 nan
1306158 43989 19 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 1 5 5.2 COc1cc(OC)cc(C(=O)Nc2ccccc2-c2nc3ccccc3s2)c1 nan
CHEMBL1513732 43989 19 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 1 5 5.2 COc1cc(OC)cc(C(=O)Nc2ccccc2-c2nc3ccccc3s2)c1 nan
1887235 44025 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 5 4.8 COc1ccc(NC(=O)CCn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)cc1 nan
CHEMBL1514436 44025 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 5 4.8 COc1ccc(NC(=O)CCn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)cc1 nan
2158481 44037 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 2 1 5 4.1 Cc1cccc(NC(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)c1C nan
CHEMBL1514582 44037 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 2 1 5 4.1 Cc1cccc(NC(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)c1C nan
2134751 44038 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 10 1 8 4.5 O=C(CCCCCn1c(=O)c2sccc2n(Cc2ccccc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1514595 44038 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 10 1 8 4.5 O=C(CCCCCn1c(=O)c2sccc2n(Cc2ccccc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
7990486 44041 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 6 2.5 COc1cccc(CNC(=O)COC(=O)/C(C#N)=C/c2ccc(N(C)C)cc2)c1 nan
CHEMBL1514625 44041 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 6 2.5 COc1cccc(CNC(=O)COC(=O)/C(C#N)=C/c2ccc(N(C)C)cc2)c1 nan
16016989 44054 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 1 5 4.1 Cc1ccc(CNC(=O)C(C)n2nc(C)c3sc4ccccc4c3c2=O)cc1 nan
CHEMBL1514781 44054 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 1 5 4.1 Cc1ccc(CNC(=O)C(C)n2nc(C)c3sc4ccccc4c3c2=O)cc1 nan
4246910 44061 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 0 10 0.0 CCOCCn1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1514858 44061 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 0 10 0.0 CCOCCn1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
16030776 44065 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 10 1.9 Cc1cc(NC(=O)CSc2nc(-c3ccccc3F)nc3c2c(=O)n(C)c(=O)n3C)no1 nan
CHEMBL1514941 44065 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 10 1.9 Cc1cc(NC(=O)CSc2nc(-c3ccccc3F)nc3c2c(=O)n(C)c(=O)n3C)no1 nan
16022121 44088 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 4 0 7 2.9 COc1ccc2c(c1)c1c(c(=O)n(-c3cccc(Cl)c3)c(=O)n1CC(=O)N1CCCC1)n2C nan
CHEMBL1515298 44088 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 4 0 7 2.9 COc1ccc2c(c1)c1c(c(=O)n(-c3cccc(Cl)c3)c(=O)n1CC(=O)N1CCCC1)n2C nan
6418314 44094 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 5 5.4 CCC(Sc1nnc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1)C(=O)NC1CCCC1 nan
CHEMBL1515335 44094 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 5 5.4 CCC(Sc1nnc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1)C(=O)NC1CCCC1 nan
16031608 44104 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 2 6 2.6 COc1ccc(NC(=O)C2CCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)CC2)c(OC)c1 nan
CHEMBL1515521 44104 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 2 6 2.6 COc1ccc(NC(=O)C2CCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)CC2)c(OC)c1 nan
16014254 44111 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 2 6 3.2 NS(=O)(=O)c1ccc(CCNC(=O)c2nc(SCc3ccccc3F)ncc2Cl)cc1 nan
CHEMBL1515689 44111 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 2 6 3.2 NS(=O)(=O)c1ccc(CCNC(=O)c2nc(SCc3ccccc3F)ncc2Cl)cc1 nan
16009753 44122 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 1 0 5 3.8 Cn1c(=O)n(-c2ccc(Br)cc2F)c(=O)c2sc3ccccc3c21 nan
CHEMBL1515791 44122 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 1 0 5 3.8 Cn1c(=O)n(-c2ccc(Br)cc2F)c(=O)c2sc3ccccc3c21 nan
16029066 44134 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 3.0 CC(=O)c1ccc(NC(=O)c2cc(S(=O)(=O)N3CCCCCC3)cn2C)cc1 nan
CHEMBL1515983 44134 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 3.0 CC(=O)c1ccc(NC(=O)c2cc(S(=O)(=O)N3CCCCCC3)cn2C)cc1 nan
16027656 44141 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 9 4.0 CC(C)Cc1nn2c(=O)cc(COC(=O)c3cccc(NC(=O)c4cccs4)c3)nc2s1 nan
CHEMBL1516060 44141 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 9 4.0 CC(C)Cc1nn2c(=O)cc(COC(=O)c3cccc(NC(=O)c4cccs4)c3)nc2s1 nan
16030468 44156 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1ccc(OCC(=O)Nc2ccccc2OCc2cc(=O)n3ccccc3n2)cc1C nan
CHEMBL1516233 44156 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1ccc(OCC(=O)Nc2ccccc2OCc2cc(=O)n3ccccc3n2)cc1C nan
15990035 44157 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 2 7 3.2 CC(C)CCNC(=O)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
CHEMBL1516237 44157 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 2 7 3.2 CC(C)CCNC(=O)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
6220215 44204 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 3 3.2 CC1=CC2=NC(=O)/C(=C/c3c(C)[nH]c4ccc(C)cc34)C(=N)N2O1 nan
CHEMBL1516846 44204 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 3 3.2 CC1=CC2=NC(=O)/C(=C/c3c(C)[nH]c4ccc(C)cc34)C(=N)N2O1 nan
3238933 44253 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 O=C(Nc1c(C(=O)Nc2cccc(F)c2)oc2ccccc12)c1ccc2c(c1)OCO2 nan
CHEMBL1517304 44253 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 O=C(Nc1c(C(=O)Nc2cccc(F)c2)oc2ccccc12)c1ccc2c(c1)OCO2 nan
24687299 44315 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 3.9 CC(=O)c1sc(NC(=O)c2cccc(N3C(=O)CCC3=O)c2)nc1-c1ccccc1 nan
CHEMBL1517943 44315 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 3.9 CC(=O)c1sc(NC(=O)c2cccc(N3C(=O)CCC3=O)c2)nc1-c1ccccc1 nan
16009652 44331 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 2 4 5.8 O=C(Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12)c1cc2ccccc2o1 nan
CHEMBL1518097 44331 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 2 4 5.8 O=C(Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12)c1cc2ccccc2o1 nan
3298558 44371 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 7 1 7 3.7 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(c2ccccc2)CC1 nan
CHEMBL1518549 44371 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 7 1 7 3.7 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(c2ccccc2)CC1 nan
5286935 44386 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 2 2 4 2.4 Cc1ccc(NC(=O)/C(C#N)=C(\N)C(Cl)(Cl)Cl)nc1 nan
CHEMBL1518626 44386 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 2 2 4 2.4 Cc1ccc(NC(=O)/C(C#N)=C(\N)C(Cl)(Cl)Cl)nc1 nan
16031509 44434 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 6 4.6 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(Cl)cc3)s2)cc1 nan
CHEMBL1519036 44434 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 6 4.6 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(Cl)cc3)s2)cc1 nan
938163 44474 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 5 3.2 CC(=O)Nc1cccc(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1519354 44474 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 5 3.2 CC(=O)Nc1cccc(-c2nnc3c4ccccc4c(C)nn23)c1 nan
2473851 44475 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 9 2 6 2.5 COc1cc(C(=O)NCCNC(=O)c2cc(OC)c(C)c(OC)c2)cc(OC)c1C nan
CHEMBL1519363 44475 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 9 2 6 2.5 COc1cc(C(=O)NCCNC(=O)c2cc(OC)c(C)c(OC)c2)cc(OC)c1C nan
24687548 44567 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 7 1 10 2.1 COc1ccc(OC)c(-c2csc(NC(=O)CSc3nnnn3C)n2)c1 nan
CHEMBL1520201 44567 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 7 1 10 2.1 COc1ccc(OC)c(-c2csc(NC(=O)CSc3nnnn3C)n2)c1 nan
1142116 44571 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 4 4.7 O=C(CSc1nc2c(c(C(F)(F)F)n1)CCc1ccccc1-2)NCc1ccccc1 nan
CHEMBL1520265 44571 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 4 4.7 O=C(CSc1nc2c(c(C(F)(F)F)n1)CCc1ccccc1-2)NCc1ccccc1 nan
2577415 44833 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 0 8 2.4 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)c2csc(N3CCCCC3)n2)cc1 nan
CHEMBL1522536 44833 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 0 8 2.4 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)c2csc(N3CCCCC3)n2)cc1 nan
16027586 44998 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 8 3.6 CCc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
CHEMBL1524058 44998 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 8 3.6 CCc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
22581682 45023 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 6 3.9 COc1ccc(-c2cn3nc(SCC(=O)NC4CCCCC4)ccc3n2)cc1 nan
CHEMBL1524339 45023 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 6 3.9 COc1ccc(-c2cn3nc(SCC(=O)NC4CCCCC4)ccc3n2)cc1 nan
2814763 45035 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 1 4.2 O=C(Nc1ccc(F)cc1)c1cc2cc(Cl)ccc2[nH]1 nan
CHEMBL1524425 45035 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 1 4.2 O=C(Nc1ccc(F)cc1)c1cc2cc(Cl)ccc2[nH]1 nan
16012570 45103 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.4 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)NCc3ccccc3Cl)c(C)nc21 nan
CHEMBL1525143 45103 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.4 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)NCc3ccccc3Cl)c(C)nc21 nan
3119681 45408 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 3 6.1 O=C(Cc1ccccc1)Nc1sc2c(c1C(=O)Nc1cccc(Cl)c1)CCCCC2 nan
CHEMBL1527765 45408 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 3 6.1 O=C(Cc1ccccc1)Nc1sc2c(c1C(=O)Nc1cccc(Cl)c1)CCCCC2 nan
3370309 45589 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 2 7 3.5 CCN(CCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)c1cccc(C)c1 nan
CHEMBL1529348 45589 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 2 7 3.5 CCN(CCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)c1cccc(C)c1 nan
3178487 45644 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.8 CCn1c(SCC(=O)N2CCC(C)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1529806 45644 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.8 CCn1c(SCC(=O)N2CCC(C)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
3161332 45897 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 4 5.4 COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1ccccc1F nan
CHEMBL1532063 45897 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 4 5.4 COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1ccccc1F nan
3787408 46000 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 7 5.3 CCCCn1c(NS(=O)(=O)c2ccc(C)cc2)c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc21 nan
CHEMBL1532953 46000 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 7 5.3 CCCCn1c(NS(=O)(=O)c2ccc(C)cc2)c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc21 nan
2105095 46001 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 7 3.7 Cc1cc(NC(=O)CSc2nc3cc(Cl)ccc3c(=O)n2CC(C)C)no1 nan
CHEMBL1532957 46001 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 7 3.7 Cc1cc(NC(=O)CSc2nc3cc(Cl)ccc3c(=O)n2CC(C)C)no1 nan
2965497 46004 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 4 0 5 4.2 O=C(c1cc(-c2ccccn2)nc2ccc(Br)cc12)N1CCN(S(=O)(=O)c2ccccc2)CC1 nan
CHEMBL1532981 46004 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 4 0 5 4.2 O=C(c1cc(-c2ccccn2)nc2ccc(Br)cc12)N1CCN(S(=O)(=O)c2ccccc2)CC1 nan
16019855 46058 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 0 5 3.8 Cc1ccccc1-c1noc(-c2cc3ccccc3oc2=O)n1 nan
CHEMBL1533477 46058 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 0 5 3.8 Cc1ccccc1-c1noc(-c2cc3ccccc3oc2=O)n1 nan
17374586 46521 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 0 4 3.5 CCC(Oc1cc(Cl)ccc1Cl)C(=O)N1CCC2(CC1)OCCO2 nan
CHEMBL1537906 46521 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 0 4 3.5 CCC(Oc1cc(Cl)ccc1Cl)C(=O)N1CCC2(CC1)OCCO2 nan
1078178 46827 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 7 2 6 3.2 COc1cc(OC)cc(C(=O)Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)c1 nan
CHEMBL1540495 46827 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 7 2 6 3.2 COc1cc(OC)cc(C(=O)Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)c1 nan
721260 46861 38 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 2 1 5 1.7 CCOC(=O)c1cc(C#N)c(S)nc1C nan
CHEMBL1540818 46861 38 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 2 1 5 1.7 CCOC(=O)c1cc(C#N)c(S)nc1C nan
657993 46873 14 None -31 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 1 4 3.4 COc1ccc(-c2c(C#N)c(S)nc3c2CCC3)cc1 nan
CHEMBL1540912 46873 14 None -31 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 1 4 3.4 COc1ccc(-c2c(C#N)c(S)nc3c2CCC3)cc1 nan
1356173 47321 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 2 4 4.8 CCOC(=O)c1c(N=C(S)Nc2ccc(C)cc2)sc2c1CCC2 nan
CHEMBL1544543 47321 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 2 4 4.8 CCOC(=O)c1c(N=C(S)Nc2ccc(C)cc2)sc2c1CCC2 nan
16195345 47451 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 2 8 0.4 Cn1c(=O)c2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)NCC3CCCO3)ccc2n(C)c1=O nan
CHEMBL1545503 47451 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 2 8 0.4 Cn1c(=O)c2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)NCC3CCCO3)ccc2n(C)c1=O nan
2868878 47466 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 3 4.1 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1cccc(F)c1 nan
CHEMBL1545607 47466 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 3 4.1 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1cccc(F)c1 nan
3186499 47486 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 8 3.5 CCc1nnc(NC(=O)CSc2nc3cc4c(cc3cc2C)OCCO4)s1 nan
CHEMBL1545790 47486 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 8 3.5 CCc1nnc(NC(=O)CSc2nc3cc4c(cc3cc2C)OCCO4)s1 nan
1485832 47554 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 1 4 4.6 O=C(Nc1ccccc1)c1cc2c(=O)c3ccccc3oc2nc1C(F)(F)F nan
CHEMBL1546403 47554 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 1 4 4.6 O=C(Nc1ccccc1)c1cc2c(=O)c3ccccc3oc2nc1C(F)(F)F nan
24892595 47733 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 2 7 3.8 COCCn1c(SCC(=O)Nc2cccc(F)c2)nc2c3ccccc3nc-2c1O nan
CHEMBL1548166 47733 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 2 7 3.8 COCCn1c(SCC(=O)Nc2cccc(F)c2)nc2c3ccccc3nc-2c1O nan
4223534 47753 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 2 4.5 CC1(C)C(CSc2nc3ccccc3[nH]2)C1(Cl)Cl nan
CHEMBL1548301 47753 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 2 4.5 CC1(C)C(CSc2nc3ccccc3[nH]2)C1(Cl)Cl nan
818439 47829 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 1 2 7 1.1 COC(=O)c1sc2nc(N)c(C#N)cc2c1N nan
CHEMBL1548988 47829 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 1 2 7 1.1 COC(=O)c1sc2nc(N)c(C#N)cc2c1N nan
1417035 47900 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 1 8 1.0 Cn1c(=O)c2c(nc(SCc3ccc(C(=O)O)cc3)n2C)n(C)c1=O nan
CHEMBL1549569 47900 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 1 8 1.0 Cn1c(=O)c2c(nc(SCc3ccc(C(=O)O)cc3)n2C)n(C)c1=O nan
1838684 47932 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 6 4.3 O=C(COc1ccc(Cl)cc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
CHEMBL1549821 47932 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 6 4.3 O=C(COc1ccc(Cl)cc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
1777240 48085 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 5 2.3 Cc1cc(OCC(=O)N2CCC(C(=O)O)CC2)c2c3c(c(=O)oc2c1)CCC3 nan
CHEMBL1551078 48085 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 5 2.3 Cc1cc(OCC(=O)N2CCC(C(=O)O)CC2)c2c3c(c(=O)oc2c1)CCC3 nan
16009855 48129 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 5 1 6 4.5 O=C(Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2sc3ccccc3c21)Nc1ccc(F)cc1F nan
CHEMBL1551826 48129 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 5 1 6 4.5 O=C(Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2sc3ccccc3c21)Nc1ccc(F)cc1F nan
16030710 48135 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 5 1 9 3.3 COC(=O)c1ccc(NC(=O)N2CCN(Cc3cc(=O)n4nc(-c5ccc(C)cc5)sc4n3)CC2)cc1 nan
CHEMBL1551878 48135 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 5 1 9 3.3 COC(=O)c1ccc(NC(=O)N2CCN(Cc3cc(=O)n4nc(-c5ccc(C)cc5)sc4n3)CC2)cc1 nan
1004076 48138 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4C)sc3n2)cc1 nan
CHEMBL1551914 48138 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4C)sc3n2)cc1 nan
7222625 48199 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 6 4.4 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(C)c(F)c3)nn2)s1 nan
CHEMBL1552706 48199 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 6 4.4 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(C)c(F)c3)nn2)s1 nan
16010352 48235 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 8 1 4 4.6 CCOC(=O)c1c(C)c(-c2ccccc2)n(CC(=O)NCCc2cccc(C)c2)c1C nan
CHEMBL1553141 48235 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 8 1 4 4.6 CCOC(=O)c1c(C)c(-c2ccccc2)n(CC(=O)NCCc2cccc(C)c2)c1C nan
16030832 48289 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 1 4 4.2 O=C(Nc1ccccc1C(=O)N1CCCCC1)c1nsc2ccccc12 nan
CHEMBL1553983 48289 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 1 4 4.2 O=C(Nc1ccccc1C(=O)N1CCCCC1)c1nsc2ccccc12 nan
16012075 48295 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 4.2 CC(=O)c1ccc(NC(=O)Cn2ncc3c4ccccc4n(Cc4ccccc4)c3c2=O)cc1 nan
CHEMBL1554061 48295 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 4.2 CC(=O)c1ccc(NC(=O)Cn2ncc3c4ccccc4n(Cc4ccccc4)c3c2=O)cc1 nan
16008778 48297 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 0 9 1.9 CCOC(=O)Cn1c(=O)oc2cc(S(=O)(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)ccc21 nan
CHEMBL1554084 48297 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 0 9 1.9 CCOC(=O)Cn1c(=O)oc2cc(S(=O)(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)ccc21 nan
3147967 48301 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 6 3.6 Cc1cccc(NC(=O)CSc2nnc3c4ccccc4n(C)c3n2)c1 nan
CHEMBL1554132 48301 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 6 3.6 Cc1cccc(NC(=O)CSc2nnc3c4ccccc4n(C)c3n2)c1 nan
1222858 48308 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 8 3.3 COC(=O)c1sc(NC(=O)/C=C/c2ccc(OC)c(OC)c2)c(C(=O)OC)c1C nan
CHEMBL1554200 48308 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 8 3.3 COC(=O)c1sc(NC(=O)/C=C/c2ccc(OC)c(OC)c2)c(C(=O)OC)c1C nan
16027476 48309 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccccc1C(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1 nan
CHEMBL1554206 48309 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccccc1C(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1 nan
15989095 48310 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 2 7 2.2 NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
CHEMBL1554211 48310 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 2 7 2.2 NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
15991109 48315 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 3 5.2 Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1ccc(F)cc1F nan
CHEMBL1554314 48315 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 3 5.2 Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1ccc(F)cc1F nan
3503858 48323 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 1 6 5.3 CCC(C)NC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1Cc1ccccc1Cl nan
CHEMBL1554470 48323 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 1 6 5.3 CCC(C)NC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1Cc1ccccc1Cl nan
16024920 48358 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 5 5.0 CCCOc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1555031 48358 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 5 5.0 CCCOc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16009072 48366 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 4 2.8 CCOc1ccc(S(=O)(=O)c2c[nH]c3ccccc3c2=O)cc1 nan
CHEMBL1555115 48366 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 4 2.8 CCOc1ccc(S(=O)(=O)c2c[nH]c3ccccc3c2=O)cc1 nan
16015125 48369 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 5 4.6 Cc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1C nan
CHEMBL1555140 48369 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 5 4.6 Cc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1C nan
9550626 48412 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 7 1 7 3.9 CCOC(=O)c1c(NC(=O)c2cc(CC(C)C)on2)sc(C(C)=O)c1C nan
CHEMBL1555685 48412 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 7 1 7 3.9 CCOC(=O)c1c(NC(=O)c2cc(CC(C)C)on2)sc(C(C)=O)c1C nan
2176795 48453 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 2 5 3.8 Cc1onc(-c2ccccc2Cl)c1C(=O)NC(=S)NCC(=O)c1ccccc1 nan
CHEMBL1556085 48453 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 2 5 3.8 Cc1onc(-c2ccccc2Cl)c1C(=O)NC(=S)NCC(=O)c1ccccc1 nan
16022893 48588 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 6 4.8 Cc1ccc(-n2nc3c(N4CCC(C(=O)NC(C)c5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1557305 48588 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 6 4.8 Cc1ccc(-n2nc3c(N4CCC(C(=O)NC(C)c5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
16011715 48656 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 6 2.9 Cc1cc(F)ccc1Nc1nc2ccccc2n2nnnc12 nan
CHEMBL1557862 48656 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 6 2.9 Cc1cc(F)ccc1Nc1nc2ccccc2n2nnnc12 nan
15989730 48661 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 5 3.6 Cc1cc(C)cc(Nc2nc3ccccc3n3cnnc23)c1 nan
CHEMBL1557912 48661 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 5 3.6 Cc1cc(C)cc(Nc2nc3ccccc3n3cnnc23)c1 nan
16011441 48746 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 9 1 6 5.9 COc1ccc(Cn2c(SCc3ccc(C(=O)NCc4ccccc4F)cc3)nc3cccnc32)cc1 nan
CHEMBL1558654 48746 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 9 1 6 5.9 COc1ccc(Cn2c(SCc3ccc(C(=O)NCc4ccccc4F)cc3)nc3cccnc32)cc1 nan
16030801 48785 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 4.4 COc1ccc(-c2cc3ccc(O)c(CN4CCCC(C)C4)c3oc2=O)cc1 nan
CHEMBL1558940 48785 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 4.4 COc1ccc(-c2cc3ccc(O)c(CN4CCCC(C)C4)c3oc2=O)cc1 nan
1970873 48788 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 0 10 3.5 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccc(F)cc5)s4)c3nc12 nan
CHEMBL1558965 48788 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 0 10 3.5 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccc(F)cc5)s4)c3nc12 nan
16024619 48803 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 7 4.3 CCOC(=O)c1ccc(NC(=O)Cn2cc(C(=O)c3ccc(CC)cc3)c(=O)c3ccc(C)nc32)cc1 nan
CHEMBL1559093 48803 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 7 4.3 CCOC(=O)c1ccc(NC(=O)Cn2cc(C(=O)c3ccc(CC)cc3)c(=O)c3ccc(C)nc32)cc1 nan
135448823 48906 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 8 2.7 Cc1cc(NC(=O)CSc2nc(O)c(C#N)c(-c3ccccc3)n2)no1 nan
CHEMBL1560048 48906 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 8 2.7 Cc1cc(NC(=O)CSc2nc(O)c(C#N)c(-c3ccccc3)n2)no1 nan
20944767 49009 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 4 3.3 O=C(CN1c2ccccc2S(=O)(=O)c2ccccc21)NCc1ccccc1 nan
CHEMBL1561113 49009 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 4 3.3 O=C(CN1c2ccccc2S(=O)(=O)c2ccccc21)NCc1ccccc1 nan
938228 49036 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 1 5 3.3 COc1cccc(-c2cc(-c3cccnc3)nc(N)c2C#N)c1 nan
CHEMBL1561334 49036 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 1 5 3.3 COc1cccc(-c2cc(-c3cccnc3)nc(N)c2C#N)c1 nan
2136514 49265 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
CHEMBL1563400 49265 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
16195481 49308 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 3 8 2.2 COc1cc2nc(S)nc(NCCc3ccc(S(N)(=O)=O)cc3)c2cc1OC nan
CHEMBL1563755 49308 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 3 8 2.2 COc1cc2nc(S)nc(NCCc3ccc(S(N)(=O)=O)cc3)c2cc1OC nan
16010206 49453 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 7 1.6 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1 nan
CHEMBL1565063 49453 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 7 1.6 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1 nan
16017589 49675 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 7 1.5 O=C(Nc1nnc(S(=O)(=O)N2CCOCC2)s1)c1ccccc1Cl nan
CHEMBL1566733 49675 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 7 1.5 O=C(Nc1nnc(S(=O)(=O)N2CCOCC2)s1)c1ccccc1Cl nan
2764046 49679 52 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 3 4.8 O=C(O)Cc1sc(-c2ccccc2Cl)nc1-c1ccccc1 nan
CHEMBL1566761 49679 52 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 3 4.8 O=C(O)Cc1sc(-c2ccccc2Cl)nc1-c1ccccc1 nan
1419199 49698 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 6 1 5 4.6 O=C(O)CCCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
1419200 49698 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 6 1 5 4.6 O=C(O)CCCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
CHEMBL1566925 49698 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 6 1 5 4.6 O=C(O)CCCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
1101443 49786 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 3 5.0 O=C(Nc1ccc2oc(-c3cccc(F)c3)nc2c1)c1ccccc1F nan
CHEMBL1567607 49786 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 3 5.0 O=C(Nc1ccc2oc(-c3cccc(F)c3)nc2c1)c1ccccc1F nan
663542 49899 15 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 5 4.2 O=C(CSc1ncnc2c1oc1ccccc12)Nc1cccc(F)c1 nan
CHEMBL1568508 49899 15 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 5 4.2 O=C(CSc1ncnc2c1oc1ccccc12)Nc1cccc(F)c1 nan
2837061 49904 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 2 3 4.9 O=C(Nc1cccc(NC(=O)c2ccc(Cl)cc2)n1)c1ccc(Cl)cc1 nan
CHEMBL1568556 49904 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 2 3 4.9 O=C(Nc1cccc(NC(=O)c2ccc(Cl)cc2)n1)c1ccc(Cl)cc1 nan
6618042 49915 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 6 3.5 CCCCn1c(=O)nc2n(-c3ccc(OC)cc3)c3ccccc3cc-2c1=O nan
CHEMBL1568603 49915 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 6 3.5 CCCCn1c(=O)nc2n(-c3ccc(OC)cc3)c3ccccc3cc-2c1=O nan
648080 49978 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 6 3.6 COc1ccc2cc(C)c(SCC(=O)Nc3cc(C)on3)nc2c1 nan
CHEMBL1569235 49978 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 6 3.6 COc1ccc2cc(C)c(SCC(=O)Nc3cc(C)on3)nc2c1 nan
2726812 50023 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 0 4 3.4 COC(=O)c1cc2cc(Cl)ccc2nc1SC nan
CHEMBL1569571 50023 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 0 4 3.4 COC(=O)c1cc2cc(Cl)ccc2nc1SC nan
802608 50167 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 2 4.3 COc1ccc(Br)cc1C(=O)Nc1cccc(C)c1C nan
CHEMBL1570796 50167 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 2 4.3 COc1ccc(Br)cc1C(=O)Nc1cccc(C)c1C nan
1247683 50188 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 6 3.2 Cc1cc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c(C)o1 nan
CHEMBL1570956 50188 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 6 3.2 Cc1cc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c(C)o1 nan
2874268 50240 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 1 5 3.0 Cc1cc(NCCCN(C)C)n2c(nc3ccccc32)c1C#N nan
CHEMBL1571576 50240 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 1 5 3.0 Cc1cc(NCCCN(C)C)n2c(nc3ccccc32)c1C#N nan
15988316 50254 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 2.7 CCOC(=O)c1ccc(NC(=O)COC(=O)c2cn(CC)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1571739 50254 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 2.7 CCOC(=O)c1ccc(NC(=O)COC(=O)c2cn(CC)c3nc(C)ccc3c2=O)cc1 nan
6037218 50325 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1572317 50325 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
995077 50410 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 4 4.3 Cn1cc(CNC(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cn1 nan
CHEMBL1573031 50410 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 4 4.3 Cn1cc(CNC(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cn1 nan
1927600 50510 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 540 8 2 5 7.1 CCc1ccccc1NC(=O)CSc1nc(C)c(C(=O)Nc2ccccc2)c(-c2ccc(Cl)cc2)c1C#N nan
CHEMBL1574096 50510 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 540 8 2 5 7.1 CCc1ccccc1NC(=O)CSc1nc(C)c(C(=O)Nc2ccccc2)c(-c2ccc(Cl)cc2)c1C#N nan
857532 50519 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 3 4.3 CCc1cc2cccc(C)c2nc1SCC(=O)NC1CCCC1 nan
CHEMBL1574178 50519 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 3 4.3 CCc1cc2cccc(C)c2nc1SCC(=O)NC1CCCC1 nan
7206308 50542 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 3.1 O=C(CSc1ccc(-c2ccc3c(c2)OCO3)nn1)Nc1nccs1 nan
CHEMBL1574382 50542 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 3.1 O=C(CSc1ccc(-c2ccc3c(c2)OCO3)nn1)Nc1nccs1 nan
2906920 50713 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 4 4.3 O=C(Nc1ccc(N2C(=O)C3CCCCC3C2=O)cc1Cl)c1cccs1 nan
CHEMBL1576225 50713 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 4 4.3 O=C(Nc1ccc(N2C(=O)C3CCCCC3C2=O)cc1Cl)c1cccs1 nan
135444827 50722 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 3.0 COc1cccc(N2CC(=O)C(c3nc4ccccc4s3)=C2N)c1 nan
CHEMBL1576321 50722 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 3.0 COc1cccc(N2CC(=O)C(c3nc4ccccc4s3)=C2N)c1 nan
4099135 50790 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 9 2 6 4.4 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1cccc(Cl)c1 nan
CHEMBL1576790 50790 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 9 2 6 4.4 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1cccc(Cl)c1 nan
652081 50995 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 8 1.8 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(Cc4cccnc4)c3nc12 nan
CHEMBL1578543 50995 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 8 1.8 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(Cc4cccnc4)c3nc12 nan
2040375 51019 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 0 6 4.7 COc1cc2oc(=O)c3c(c2cc1OCC(=O)c1c(C)n(C)c2ccccc12)CCCC3 nan
CHEMBL1578721 51019 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 0 6 4.7 COc1cc2oc(=O)c3c(c2cc1OCC(=O)c1c(C)n(C)c2ccccc12)CCCC3 nan
5100816 51174 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 10 2 6 3.0 O=C(COC(=O)c1cccnc1SCC(=O)NCc1ccccc1)NCc1ccccc1 nan
CHEMBL1580143 51174 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 10 2 6 3.0 O=C(COC(=O)c1cccnc1SCC(=O)NCc1ccccc1)NCc1ccccc1 nan
2823757 51713 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 1 2 4.4 CC(C)(C)c1ccc(C(=O)Nc2ccc(F)cc2)s1 nan
CHEMBL1584690 51713 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 1 2 4.4 CC(C)(C)c1ccc(C(=O)Nc2ccc(F)cc2)s1 nan
1447358 51926 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 2 6 1.7 CC(C)C(=O)NNC(=O)CN1CCN(c2nc(-c3ccccc3)cs2)CC1 nan
CHEMBL1586366 51926 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 2 6 1.7 CC(C)C(=O)NNC(=O)CN1CCN(c2nc(-c3ccccc3)cs2)CC1 nan
2123807 52101 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 2 7 0.9 COc1ccc(C(=O)Nc2cccc3c2C(=O)NC3=O)cc1S(=O)(=O)N1CCOCC1 nan
CHEMBL1587750 52101 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 2 7 0.9 COc1ccc(C(=O)Nc2cccc3c2C(=O)NC3=O)cc1S(=O)(=O)N1CCOCC1 nan
2639566 52310 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 0 6 3.1 COc1ccc(C(=O)COc2ccc3ccc(=O)oc3c2)c(OC)c1 nan
CHEMBL1589654 52310 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 0 6 3.1 COc1ccc(C(=O)COc2ccc3ccc(=O)oc3c2)c(OC)c1 nan
16027668 52339 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 8 3.4 COc1ccccc1C(=O)Nc1cccc(C(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
CHEMBL1589886 52339 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 8 3.4 COc1ccccc1C(=O)Nc1cccc(C(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
16027394 52348 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 1 8 3.4 Cc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
CHEMBL1589930 52348 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 1 8 3.4 Cc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
16007616 52364 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 5 3.6 CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)NCc1ccc(F)cc1)cn2C nan
CHEMBL1590166 52364 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 5 3.6 CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)NCc1ccc(F)cc1)cn2C nan
16018888 52381 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 3 0 5 5.2 Cc1nnc(SCc2ccccc2Cl)c2cc3sccc3n12 nan
CHEMBL1590393 52381 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 3 0 5 5.2 Cc1nnc(SCc2ccccc2Cl)c2cc3sccc3n12 nan
2058614 52384 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 0 8 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1cc(C)cc(C)c1 nan
CHEMBL1590410 52384 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 0 8 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1cc(C)cc(C)c1 nan
16025295 52395 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 7 1 6 5.8 CCc1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)c1 nan
CHEMBL1590637 52395 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 7 1 6 5.8 CCc1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)c1 nan
16017896 52435 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 0 7 2.7 COc1ccc(N2CCN(C(=O)c3sc4nc5n(c(=O)c4c3C)CCC5)CC2)cc1 nan
CHEMBL1591031 52435 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 0 7 2.7 COc1ccc(N2CCN(C(=O)c3sc4nc5n(c(=O)c4c3C)CCC5)CC2)cc1 nan
16024829 52473 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 1 4 4.6 O=C(Nc1ccc(F)cc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1591484 52473 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 1 4 4.6 O=C(Nc1ccc(F)cc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
16027514 52484 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)c1 nan
CHEMBL1591656 52484 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)c1 nan
16012296 52491 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 2 5.0 Cc1cccc(NC(=O)c2ccc(-c3ccccc3)s2)c1 nan
CHEMBL1591740 52491 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 2 5.0 Cc1cccc(NC(=O)c2ccc(-c3ccccc3)s2)c1 nan
16019608 52541 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 8 3.3 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)C)c2sccc23)cc1 nan
CHEMBL1592430 52541 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 8 3.3 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)C)c2sccc23)cc1 nan
135546866 52597 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 2 4 3.7 Cc1ccc(NC(=O)C(C)Sc2nc3c(c(=O)[nH]2)CCCC3)cc1Cl nan
CHEMBL1593216 52597 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 2 4 3.7 Cc1ccc(NC(=O)C(C)Sc2nc3c(c(=O)[nH]2)CCCC3)cc1Cl nan
3955100 52603 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 8 1 7 4.2 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(C)ccc3OC)o2)cc1 nan
CHEMBL1593290 52603 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 8 1 7 4.2 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(C)ccc3OC)o2)cc1 nan
16019825 52620 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 2 4 3.2 Cc1ccc(C)c(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)C2)c1 nan
CHEMBL1593576 52620 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 2 4 3.2 Cc1ccc(C)c(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)C2)c1 nan
7598919 52814 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 5 3.5 CCOC(=O)c1ccc(NC(=O)c2cccn(Cc3ccccc3F)c2=O)cc1 nan
CHEMBL1595394 52814 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 5 3.5 CCOC(=O)c1ccc(NC(=O)c2cccn(Cc3ccccc3F)c2=O)cc1 nan
2135415 52849 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 6 2.0 Cc1ccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)cc1 nan
CHEMBL1595713 52849 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 6 2.0 Cc1ccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)cc1 nan
15988650 52896 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 5 5.6 Cc1cc(NC(=O)c2cc(-c3ccc(Br)cc3)on2)nn1Cc1ccc(Cl)cc1 nan
CHEMBL1596161 52896 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 5 5.6 Cc1cc(NC(=O)c2cc(-c3ccc(Br)cc3)on2)nn1Cc1ccc(Cl)cc1 nan
16009387 52915 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 1 7 3.9 O=C(Cn1cc(S(=O)(=O)c2ccc(Cl)cc2)c(=O)c2ccccc21)Nc1ccc2c(c1)OCO2 nan
CHEMBL1596294 52915 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 1 7 3.9 O=C(Cn1cc(S(=O)(=O)c2ccc(Cl)cc2)c(=O)c2ccccc21)Nc1ccc2c(c1)OCO2 nan
16028259 52939 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 6 3.0 CCOc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccc(F)cc4)ccn3n2)cc1 nan
CHEMBL1596560 52939 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 6 3.0 CCOc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccc(F)cc4)ccn3n2)cc1 nan
1450700 52953 2 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 0 7 2.5 CCOC(=O)CSc1nc2cc3c(cc2cc1C#N)OCCO3 nan
CHEMBL1596663 52953 2 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 0 7 2.5 CCOC(=O)CSc1nc2cc3c(cc2cc1C#N)OCCO3 nan
859504 52971 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 0 6 3.3 Cc1cc2cc3c(cc2nc1SCC(=O)OC(C)C)OCO3 nan
CHEMBL1596835 52971 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 0 6 3.3 Cc1cc2cc3c(cc2nc1SCC(=O)OC(C)C)OCO3 nan
20903879 52983 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 8 1.7 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)c1 nan
CHEMBL1596921 52983 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 8 1.7 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)c1 nan
5922522 53045 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 9 1 6 4.7 CCCCOc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccncc2)c(C)c1 nan
CHEMBL1597564 53045 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 9 1 6 4.7 CCCCOc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccncc2)c(C)c1 nan
16031965 53050 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 2 6 4.1 COc1ccc(-c2nc(C)c(CCNC(=O)C(=O)Nc3c(C)cccc3C)s2)cc1OC nan
CHEMBL1597608 53050 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 2 6 4.1 COc1ccc(-c2nc(C)c(CCNC(=O)C(=O)Nc3c(C)cccc3C)s2)cc1OC nan
4656755 53070 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 5 3.9 COc1ccc(C(=O)Nc2cc(C)c3c(=O)oc4ccccc4c3n2)cc1 nan
CHEMBL1597754 53070 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 5 3.9 COc1ccc(C(=O)Nc2cc(C)c3c(=O)oc4ccccc4c3n2)cc1 nan
16030399 53090 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 0 4 4.9 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCC(C)CC2)cc1 nan
CHEMBL1597953 53090 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 0 4 4.9 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCC(C)CC2)cc1 nan
23603072 53234 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 0 7 0.7 CC1CCCN(C(=O)CCS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)C1 nan
CHEMBL1599245 53234 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 0 7 0.7 CC1CCCN(C(=O)CCS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)C1 nan
16009708 53385 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 2 5 5.0 COc1ccc(CC(=O)Nc2c(C(=O)Nc3ccc(F)cc3)oc3ccccc23)cc1OC nan
CHEMBL1600646 53385 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 2 5 5.0 COc1ccc(CC(=O)Nc2c(C(=O)Nc3ccc(F)cc3)oc3ccccc23)cc1OC nan
1093818 53458 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1cccnc1)c1cc(-c2ccc(Cl)cc2Cl)on1 nan
CHEMBL1601278 53458 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1cccnc1)c1cc(-c2ccc(Cl)cc2Cl)on1 nan
4327872 53542 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 0 6 1.4 CC1CN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC(C)O1 nan
CHEMBL1602225 53542 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 0 6 1.4 CC1CN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC(C)O1 nan
7199971 53696 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 8 3.5 Cc1ccc(-n2ncc3c(SCC(=O)Nc4cc(C)on4)ncnc32)c(C)c1 nan
CHEMBL1603605 53696 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 8 3.5 Cc1ccc(-n2ncc3c(SCC(=O)Nc4cc(C)on4)ncnc32)c(C)c1 nan
22522531 53704 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 1 4 3.5 CCc1cccc(NC(=O)Cn2c(=O)c3cccn3c3ccccc32)c1 nan
CHEMBL1603663 53704 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 1 4 3.5 CCc1cccc(NC(=O)Cn2c(=O)c3cccn3c3ccccc32)c1 nan
7763635 53794 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 7 0 7 1.7 COc1ccc(C(=O)COC(=O)CN2C(=O)c3ccccc3C2=O)c(OC)c1 nan
CHEMBL1604328 53794 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 7 0 7 1.7 COc1ccc(C(=O)COC(=O)CN2C(=O)c3ccccc3C2=O)c(OC)c1 nan
1072346 53907 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.5 O=C(CSc1nc(-c2ccccc2)nc2ccccc12)Nc1nccs1 nan
CHEMBL1605363 53907 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.5 O=C(CSc1nc(-c2ccccc2)nc2ccccc12)Nc1nccs1 nan
1005145 53944 14 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.6 N#Cc1cc2c(nc1SCC(=O)Nc1sc3c(c1C#N)CCC3)CCC2 nan
CHEMBL1605614 53944 14 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.6 N#Cc1cc2c(nc1SCC(=O)Nc1sc3c(c1C#N)CCC3)CCC2 nan
15991041 53998 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 2 3 5.7 CCCOc1ccc(C(=O)Nc2ccc(NC(=O)c3ccccc3)c(Br)c2)cc1 nan
CHEMBL1606046 53998 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 2 3 5.7 CCCOc1ccc(C(=O)Nc2ccc(NC(=O)c3ccccc3)c(Br)c2)cc1 nan
2934348 54158 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 2 6 3.4 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccc(O)c1)c1ccco1 nan
CHEMBL1607257 54158 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 2 6 3.4 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccc(O)c1)c1ccco1 nan
16027345 54224 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 4.4 CCCNC(=O)Cn1nc(-c2ccc(C)c(C)c2)c2cnc3ccc(OC)cc3c21 nan
CHEMBL1607743 54224 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 4.4 CCCNC(=O)Cn1nc(-c2ccc(C)c(C)c2)c2cnc3ccc(OC)cc3c21 nan
753354 54234 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 0 6 2.6 O=C1c2ccccc2C(=O)N1c1nc2nccc(-c3ccccc3)n2n1 nan
CHEMBL1607842 54234 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 0 6 2.6 O=C1c2ccccc2C(=O)N1c1nc2nccc(-c3ccccc3)n2n1 nan
3512516 54367 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 7 4.2 CCOc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)cc1 nan
CHEMBL1609027 54367 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 7 4.2 CCOc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)cc1 nan
16011054 54381 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 6 4.0 CCc1cc2c(cc3c(=O)n(CCCC(=O)NCc4cccc(Cl)c4)ncn32)s1 nan
CHEMBL1609118 54381 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 6 4.0 CCc1cc2c(cc3c(=O)n(CCCC(=O)NCc4cccc(Cl)c4)ncn32)s1 nan
2422324 54486 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 3 8 -0.1 COCCn1c(N)c(C(=S)NC(=O)c2cccs2)c(=O)[nH]c1=O nan
CHEMBL1609964 54486 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 3 8 -0.1 COCCn1c(N)c(C(=S)NC(=O)c2cccs2)c(=O)[nH]c1=O nan
16007504 54544 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 6 1 4 5.2 COc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
CHEMBL1610456 54544 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 6 1 4 5.2 COc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
2134793 54553 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 0 6 5.6 COCCCn1c(SCc2cccc(Cl)c2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1610529 54553 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 0 6 5.6 COCCCn1c(SCc2cccc(Cl)c2)nc2c(sc3ccccc32)c1=O nan
3374134 54580 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 4 2.4 O=C(Cn1c(=S)[nH]c2ccccc2c1=O)NCCc1ccccc1 nan
CHEMBL1610861 54580 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 4 2.4 O=C(Cn1c(=S)[nH]c2ccccc2c1=O)NCCc1ccccc1 nan
3185781 54668 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 10 3 8 2.2 COCCN(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCCC1)c1ccc(N(C)C)cc1 nan
CHEMBL1611537 54668 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 10 3 8 2.2 COCCN(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCCC1)c1ccc(N(C)C)cc1 nan
3353363 54681 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 6 4.1 COc1ccc(C2CC(=O)c3cnc(N4CCc5ccccc54)nc3C2)cc1OC nan
CHEMBL1611722 54681 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 6 4.1 COc1ccc(C2CC(=O)c3cnc(N4CCc5ccccc54)nc3C2)cc1OC nan
2201483 55632 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
5739455 55632 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
9587736 55632 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
CHEMBL1442349 55632 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
CHEMBL1621693 55632 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
354678 55817 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 1.6 CCC1(OC(=O)CN)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
CHEMBL1518154 55817 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 1.6 CCC1(OC(=O)CN)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
CHEMBL1623188 55817 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 1.6 CCC1(OC(=O)CN)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
24792219 55949 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 4 6.5 Fc1ccc(-[n+]2nc(Nc3ccccc3)sc2-c2ccc(OCc3ccccc3)cc2)cc1 nan
CHEMBL1551405 55949 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 4 6.5 Fc1ccc(-[n+]2nc(Nc3ccccc3)sc2-c2ccc(OCc3ccccc3)cc2)cc1 nan
CHEMBL1624286 55949 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 4 6.5 Fc1ccc(-[n+]2nc(Nc3ccccc3)sc2-c2ccc(OCc3ccccc3)cc2)cc1 nan
3490356 72429 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 0 5 2.2 C#CCn1/c(=N/C(=O)CSC(C)=O)sc2cc(F)ccc21 nan
CHEMBL1988684 72429 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 0 5 2.2 C#CCn1/c(=N/C(=O)CSC(C)=O)sc2cc(F)ccc21 nan
1522244 85464 79 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 164 0 1 3 1.9 Cn1c(S)nc2ccccc21 nan
CHEMBL227086 85464 79 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 164 0 1 3 1.9 Cn1c(S)nc2ccccc21 nan
25252625 107588 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 6 1 5 1.8 COc1ccc(CC(=O)N/N=C/c2cccnc2)cc1OC nan
CHEMBL3189886 107588 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 6 1 5 1.8 COc1ccc(CC(=O)N/N=C/c2cccnc2)cc1OC nan
9701594 107744 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 2 6 2.1 O=C(N/N=C1\C/C(=N\NC(=O)c2ccncc2)c2ccccc21)c1ccncc1 nan
CHEMBL3191689 107744 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 2 6 2.1 O=C(N/N=C1\C/C(=N\NC(=O)c2ccncc2)c2ccccc21)c1ccncc1 nan
4141152 108839 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 0 5 2.6 CCOC(=O)c1s/c(=N\C(=O)c2cccc(C)c2)n(C)c1C nan
CHEMBL3210377 108839 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 0 5 2.6 CCOC(=O)c1s/c(=N\C(=O)c2cccc(C)c2)n(C)c1C nan
2150923 109042 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 0 7 3.1 CCn1/c(=N/C(=O)c2cccc(N3C(=O)CCC3=O)c2)sc2c(OC)ccc(OC)c21 nan
CHEMBL3212992 109042 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 0 7 3.1 CCn1/c(=N/C(=O)c2cccc(N3C(=O)CCC3=O)c2)sc2c(OC)ccc(OC)c21 nan
1477780 199056 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 1 6 3.0 COc1cc(-c2nc3ccc(N4CCN(C)CC4)cc3[nH]2)cc(OC)c1OC nan
CHEMBL587856 199056 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 1 6 3.0 COc1cc(-c2nc3ccc(N4CCN(C)CC4)cc3[nH]2)cc(OC)c1OC nan
7190643 21024 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1311897 21024 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
1739479 21369 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 0 4 6.0 Cc1cc(Br)cc2c(C(=O)OCC(=O)c3ccccc3)cc(-c3ccccc3)nc12 nan
CHEMBL1314681 21369 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 0 4 6.0 Cc1cc(Br)cc2c(C(=O)OCC(=O)c3ccccc3)cc(-c3ccccc3)nc12 nan
15988299 21766 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
CHEMBL1319322 21766 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
4146227 26869 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 7 5.6 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1363837 26869 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 7 5.6 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
15988966 30829 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 10 1 4 6.5 CC(C)CN(CCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12)CC(C)C nan
CHEMBL1397188 30829 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 10 1 4 6.5 CC(C)CN(CCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12)CC(C)C nan
1398096 31170 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 7 2 5 2.8 CC(C)c1nnc(NC(=O)CCC(=O)NCc2ccc(F)cc2)s1 nan
CHEMBL1400798 31170 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 7 2 5 2.8 CC(C)c1nnc(NC(=O)CCC(=O)NCc2ccc(F)cc2)s1 nan
24792315 31506 2 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 9 1.9 CCc1nnc(NC(=O)CSc2nnc3nc(C)cc(C)n23)s1 nan
CHEMBL1403815 31506 2 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 9 1.9 CCc1nnc(NC(=O)CSc2nnc3nc(C)cc(C)n23)s1 nan
15991483 39549 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 8 0 6 6.1 CCOc1ccc(-c2nnc(SCC(=O)c3ccc(Br)cc3)n2-c2ccccc2)cc1 nan
CHEMBL1473564 39549 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 8 0 6 6.1 CCOc1ccc(-c2nnc(SCC(=O)c3ccc(Br)cc3)n2-c2ccccc2)cc1 nan
4299978 43826 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 9 1.5 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nnc2ccccn12 nan
CHEMBL1511455 43826 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 9 1.5 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nnc2ccccn12 nan
16019368 52647 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 10 4.5 COc1cc(Nc2nc3c(S(=O)(=O)c4ccc(C)c(C)c4)nnn3c3ccsc23)cc(OC)c1 nan
CHEMBL1593977 52647 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 10 4.5 COc1cc(Nc2nc3c(S(=O)(=O)c4ccc(C)c(C)c4)nnn3c3ccsc23)cc(OC)c1 nan
814542 53076 25 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 215 0 2 3 2.7 Cc1ccc2[nH]c3c(S)ncnc3c2c1 nan
CHEMBL1597829 53076 25 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 215 0 2 3 2.7 Cc1ccc2[nH]c3c(S)ncnc3c2c1 nan
9619102 72413 8 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 1 11 -0.4 COc1ccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1OC nan
CHEMBL1988156 72413 8 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 1 11 -0.4 COc1ccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1OC nan
16010435 6166 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 6 1 8 5.0 COc1ccccc1CNc1nc2c(S(=O)(=O)c3ccc(C)c(C)c3)nnn2c2ccc(Cl)cc12 nan
CHEMBL1081265 6166 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 6 1 8 5.0 COc1ccccc1CNc1nc2c(S(=O)(=O)c3ccc(C)c(C)c3)nnn2c2ccc(Cl)cc12 nan
1375940 7524 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 5 1.0 COc1ccccc1NC=C1C(=O)N(C)C(=O)N(C)C1=O nan
CHEMBL1087646 7524 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 5 1.0 COc1ccccc1NC=C1C(=O)N(C)C(=O)N(C)C1=O nan
16019310 10727 11 None -47 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 8 4.2 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccc(F)cc2)c2sccc23)cc1 nan
CHEMBL1171436 10727 11 None -47 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 8 4.2 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccc(F)cc2)c2sccc23)cc1 nan
16019394 10833 8 None -37 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 1 8 4.6 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 nan
CHEMBL1172405 10833 8 None -37 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 1 8 4.6 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 nan
16019397 10927 11 None -54 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 9 4.5 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
CHEMBL1173286 10927 11 None -54 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 9 4.5 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
684664 15408 27 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 5 2.7 N#Cc1c(N)nc(N2CCCC2)c(C#N)c1-c1ccccc1 nan
CHEMBL1215029 15408 27 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 5 2.7 N#Cc1c(N)nc(N2CCCC2)c(C#N)c1-c1ccccc1 nan
34768 16369 59 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O nan
CHEMBL1230732 16369 59 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O nan
CHEMBL3392220 16369 59 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O nan
3733180 19647 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.7 O=C(Nc1nnc(-c2ccccc2F)s1)c1ccccc1F nan
CHEMBL1300733 19647 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.7 O=C(Nc1nnc(-c2ccccc2F)s1)c1ccccc1F nan
3815083 19686 30 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 1 1 5 2.5 N#Cc1cnn2c(N)c(-c3ccc(Cl)cc3)cnc12 nan
CHEMBL1301028 19686 30 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 1 1 5 2.5 N#Cc1cnn2c(N)c(-c3ccc(Cl)cc3)cnc12 nan
2219338 19839 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 2 3 5.0 O=C(Nc1cccc(C(F)(F)F)c1)c1cccnc1NCCc1ccccc1 nan
CHEMBL1302293 19839 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 2 3 5.0 O=C(Nc1cccc(C(F)(F)F)c1)c1cccnc1NCCc1ccccc1 nan
1217579 19845 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 0 6 4.5 N#Cc1ccc(-c2nc3cc(C#N)c(C#N)cc3nc2-c2ccccc2)cc1C#N nan
CHEMBL1302356 19845 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 0 6 4.5 N#Cc1ccc(-c2nc3cc(C#N)c(C#N)cc3nc2-c2ccccc2)cc1C#N nan
1244329 19919 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 7 3.6 COC(=O)c1c(-c2cccnc2)csc1NC(=O)c1ccc2c(c1)OCO2 nan
CHEMBL1302889 19919 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 7 3.6 COC(=O)c1c(-c2cccnc2)csc1NC(=O)c1ccc2c(c1)OCO2 nan
2740109 20056 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 2 0 5 3.5 N#Cc1c(N2CCOCC2)nsc1-c1ccc(C(F)(F)F)cc1 nan
CHEMBL1303994 20056 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 2 0 5 3.5 N#Cc1c(N2CCOCC2)nsc1-c1ccc(C(F)(F)F)cc1 nan
1462693 20326 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 8 2 7 2.3 COc1ccc(CNC(=O)CSc2nnc(NC(=O)C3CC3)s2)cc1 nan
CHEMBL1306151 20326 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 8 2 7 2.3 COc1ccc(CNC(=O)CSc2nnc(NC(=O)C3CC3)s2)cc1 nan
2158311 20328 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 5 5.1 O=C(CSc1ncnc2c1oc1ccccc12)Nc1ccccc1C(F)(F)F nan
CHEMBL1306166 20328 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 5 5.1 O=C(CSc1ncnc2c1oc1ccccc12)Nc1ccccc1C(F)(F)F nan
940263 20363 40 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 175 0 1 2 2.8 Cc1cc(S)c2ccccc2n1 nan
CHEMBL1306515 20363 40 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 175 0 1 2 2.8 Cc1cc(S)c2ccccc2n1 nan
3678328 20660 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 5 4.0 O=C(COC(=O)c1cccc(Br)c1)Nc1cccc2c1C(=O)c1ccccc1C2=O nan
CHEMBL1308878 20660 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 5 4.0 O=C(COC(=O)c1cccc(Br)c1)Nc1cccc2c1C(=O)c1ccccc1C2=O nan
3942275 20797 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 7 4.6 CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3nc(-c4cc5ccccc5o4)cs3)cc2)CC(C)O1 nan
CHEMBL1310132 20797 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 7 4.6 CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3nc(-c4cc5ccccc5o4)cs3)cc2)CC(C)O1 nan
2744150 21252 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 7 4.3 Cc1nc(-c2nnc(SCC(=O)Nc3cc(Cl)cc(Cl)c3)n2C)cs1 nan
CHEMBL1313563 21252 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 7 4.3 Cc1nc(-c2nnc(SCC(=O)Nc3cc(Cl)cc(Cl)c3)n2C)cs1 nan
2997549 21323 8 None -7 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 8 2.9 Cc1ccc(S(=O)(=O)c2c(N)n(CCN3CCOCC3)c3nc4ccccc4nc23)cc1C nan
CHEMBL1314156 21323 8 None -7 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 8 2.9 Cc1ccc(S(=O)(=O)c2c(N)n(CCN3CCOCC3)c3nc4ccccc4nc23)cc1C nan
16009918 21334 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 1 7 1.5 Cc1ccc(Cl)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1314250 21334 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 1 7 1.5 Cc1ccc(Cl)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
135458483 21348 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 1.7 Cc1ccn2c(=O)c(C(=O)NCCc3ccccc3)c(O)nc2c1 nan
CHEMBL1314355 21348 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 1.7 Cc1ccn2c(=O)c(C(=O)NCCc3ccccc3)c(O)nc2c1 nan
16024181 21370 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 3 0 4 3.9 Cc1cccc(N2C(=O)CS(=O)(=O)C23C(=O)N(Cc2c(F)cccc2Cl)c2ccccc23)c1 nan
CHEMBL1314689 21370 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 3 0 4 3.9 Cc1cccc(N2C(=O)CS(=O)(=O)C23C(=O)N(Cc2c(F)cccc2Cl)c2ccccc23)c1 nan
4913767 21381 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 0 7 3.2 COC(=O)Cc1c(C)c2ccc3c(c2oc1=O)CN(Cc1ccccc1OC)CO3 nan
CHEMBL1314916 21381 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 0 7 3.2 COC(=O)Cc1c(C)c2ccc3c(c2oc1=O)CN(Cc1ccccc1OC)CO3 nan
16027662 21392 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 7 3.5 O=C(Nc1cccc(C(=O)OCc2cc(=O)n3ccsc3n2)c1)c1ccc(F)cc1 nan
CHEMBL1315065 21392 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 7 3.5 O=C(Nc1cccc(C(=O)OCc2cc(=O)n3ccsc3n2)c1)c1ccc(F)cc1 nan
16021060 21425 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 3.7 COc1ccc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)cc1OC nan
CHEMBL1315440 21425 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 3.7 COc1ccc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)cc1OC nan
4524401 21437 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 8 1 8 4.0 COC(=O)c1ccccc1NC(=O)CSc1nc2ccsc2c(=O)n1CCC(C)C nan
CHEMBL1315570 21437 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 8 1 8 4.0 COC(=O)c1ccccc1NC(=O)CSc1nc2ccsc2c(=O)n1CCC(C)C nan
16020822 21439 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 5 6.0 O=C(NC1CCCCC1)c1ccc(Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
CHEMBL1315619 21439 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 5 6.0 O=C(NC1CCCCC1)c1ccc(Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
16016226 21455 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 5.0 CC(=O)c1cccc(NC(=O)c2nc(-c3ccccc3)n(-c3cccc(Cl)c3)n2)c1 nan
CHEMBL1315816 21455 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 5.0 CC(=O)c1cccc(NC(=O)c2nc(-c3ccccc3)n(-c3cccc(Cl)c3)n2)c1 nan
16009840 21458 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 5.2 COc1ccccc1NC(=O)c1oc2ccccc2c1NC(=O)C1CCCCC1 nan
CHEMBL1315829 21458 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 5.2 COc1ccccc1NC(=O)c1oc2ccccc2c1NC(=O)C1CCCCC1 nan
16025104 21476 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 5 4.4 CC(=O)c1cccc(NC(=O)c2cnn(-c3cccc(C)c3)c2-n2cccc2)c1 nan
CHEMBL1316030 21476 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 5 4.4 CC(=O)c1cccc(NC(=O)c2cnn(-c3cccc(C)c3)c2-n2cccc2)c1 nan
1083262 21484 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 0 5 4.4 CCOC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)c1C#N nan
CHEMBL1316119 21484 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 0 5 4.4 CCOC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)c1C#N nan
20940443 21503 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 3 4.5 CCCNC(=O)c1cc(-c2ccccc2)c(N2CCCCC2)s1 nan
CHEMBL1316420 21503 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 3 4.5 CCCNC(=O)c1cc(-c2ccccc2)c(N2CCCCC2)s1 nan
16022216 21548 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 4 4.7 CC(=O)c1ccc(NC(=O)CC(c2cccs2)N2Cc3ccccc3C2=O)cc1 nan
CHEMBL1317049 21548 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 4 4.7 CC(=O)c1ccc(NC(=O)CC(c2cccs2)N2Cc3ccccc3C2=O)cc1 nan
16027421 21555 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 8 3.7 COc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4c(C)csc4n3)c2)c1 nan
CHEMBL1317129 21555 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 8 3.7 COc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4c(C)csc4n3)c2)c1 nan
2159322 21569 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 3 0 6 3.6 CCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2c(C)ccc(OC)c21 nan
CHEMBL1317343 21569 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 3 0 6 3.6 CCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2c(C)ccc(OC)c21 nan
16028188 21586 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 2 3 3.8 Cc1cccc(NC(=O)c2cc3c([nH]c2=O)CC(c2ccccc2)CC3=O)c1 nan
CHEMBL1317555 21586 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 2 3 3.8 Cc1cccc(NC(=O)c2cc3c([nH]c2=O)CC(c2ccccc2)CC3=O)c1 nan
16023037 21601 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 6 3.6 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccc(Cl)cc3)s2)cc1 nan
CHEMBL1317727 21601 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 6 3.6 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccc(Cl)cc3)s2)cc1 nan
2227086 21608 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 3 2.5 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1cccc(Cl)c1 nan
CHEMBL1317881 21608 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 3 2.5 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1cccc(Cl)c1 nan
16024891 21644 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 5 4.9 CSc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1318327 21644 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 5 4.9 CSc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16025877 21671 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 8 2.9 CC(C)Oc1ccc(CNC(=O)c2cnc3sc(N4CCCCC4)nn3c2=O)cc1 nan
CHEMBL1318545 21671 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 8 2.9 CC(C)Oc1ccc(CNC(=O)c2cnc3sc(N4CCCCC4)nn3c2=O)cc1 nan
16445400 21694 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 2 1 5 2.8 Cc1nonc1NC(=O)c1oc2ccc(F)cc2c1C nan
CHEMBL1318745 21694 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 2 1 5 2.8 Cc1nonc1NC(=O)c1oc2ccc(F)cc2c1C nan
16022946 21789 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1319510 21789 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
16022818 21855 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 5.2 Cc1ccc(Cl)cc1NC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)CC1 nan
CHEMBL1320089 21855 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 5.2 Cc1ccc(Cl)cc1NC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)CC1 nan
4183241 21860 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.5 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccc(F)cc3)n2)cc1 nan
CHEMBL1320138 21860 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.5 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccc(F)cc3)n2)cc1 nan
3167480 21870 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 6 5.1 Cc1ccc2nc(SCC(=O)Nc3ccc4sc(C)nc4c3)c(C#N)cc2c1 nan
CHEMBL1320193 21870 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 6 5.1 Cc1ccc2nc(SCC(=O)Nc3ccc4sc(C)nc4c3)c(C#N)cc2c1 nan
16023651 21873 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 7 3 5 3.6 Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(CS(=O)(=O)Cc2cccc(C)c2)N3)cc1 nan
CHEMBL1320214 21873 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 7 3 5 3.6 Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(CS(=O)(=O)Cc2cccc(C)c2)N3)cc1 nan
16009865 21902 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 1 6 3.6 O=C(Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
CHEMBL1320479 21902 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 1 6 3.6 O=C(Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
3613580 22037 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 1 5 3.7 CNc1nc(-c2ccccc2)nc(-c2ccc(OC)cc2)c1C#N nan
CHEMBL1321693 22037 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 1 5 3.7 CNc1nc(-c2ccccc2)nc(-c2ccc(OC)cc2)c1C#N nan
16026062 22202 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 1 7 2.6 Cc1cccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)c1C nan
CHEMBL1323207 22202 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 1 7 2.6 Cc1cccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)c1C nan
720155 22232 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 2 2 4.8 Cc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(C)c3)c2)c1 nan
CHEMBL1323476 22232 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 2 2 4.8 Cc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(C)c3)c2)c1 nan
866639 22255 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 6 2.4 Cc1cccn2c(=O)c3cc(C(=O)N4COCC4(C)C)sc3nc12 nan
CHEMBL1323660 22255 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 6 2.4 Cc1cccn2c(=O)c3cc(C(=O)N4COCC4(C)C)sc3nc12 nan
7597258 22380 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 4 3.7 Cc1ccc(-c2nnc(NC(=O)Cc3ccc(F)cc3)o2)c(C)c1 nan
CHEMBL1324652 22380 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 4 3.7 Cc1ccc(-c2nnc(NC(=O)Cc3ccc(F)cc3)o2)c(C)c1 nan
20903561 22437 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 2 5 3.1 O=C(Nc1ccc(F)cc1)C1CCCN(S(=O)(=O)c2ccc3nc(O)ccc3c2)C1 nan
CHEMBL1325113 22437 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 2 5 3.1 O=C(Nc1ccc(F)cc1)C1CCCN(S(=O)(=O)c2ccc3nc(O)ccc3c2)C1 nan
1239703 22454 8 None -7 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.0 CCc1nnc(NC(=O)CSc2nc3c(cc2C#N)CCCC3)s1 nan
CHEMBL1325279 22454 8 None -7 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.0 CCc1nnc(NC(=O)CSc2nc3c(cc2C#N)CCCC3)s1 nan
4053254 22550 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 2 5 3.1 COc1ccc(NC(=O)CCn2c(=S)[nH]c3ccccc3c2=O)cc1 nan
CHEMBL1326345 22550 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 2 5 3.1 COc1ccc(NC(=O)CCn2c(=S)[nH]c3ccccc3c2=O)cc1 nan
2742890 22636 5 None -7 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 3 2 2 4.3 COc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3Br)cc2c1 nan
CHEMBL1327081 22636 5 None -7 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 3 2 2 4.3 COc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3Br)cc2c1 nan
16030465 22701 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 4 4.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)N1CCCCC1 nan
CHEMBL1327646 22701 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 4 4.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)N1CCCCC1 nan
2330460 22760 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 7 5.0 Cc1nn(-c2ccccc2Cl)c2sc(C(=O)Nc3nnc(C4CC4)s3)cc12 nan
CHEMBL1328005 22760 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 7 5.0 Cc1nn(-c2ccccc2Cl)c2sc(C(=O)Nc3nnc(C4CC4)s3)cc12 nan
1048410 23203 8 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 4 5.6 COc1cc(NC(=O)c2ccc(-c3ccc(Br)cc3)o2)ccc1NC(=O)C(C)C nan
CHEMBL1331632 23203 8 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 4 5.6 COc1cc(NC(=O)c2ccc(-c3ccc(Br)cc3)o2)ccc1NC(=O)C(C)C nan
1088560 23212 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 1 3 4.1 CC(=O)c1cn(CC(=O)Nc2ccc(C)c(C)c2)c2ccccc12 nan
CHEMBL1331684 23212 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 1 3 4.1 CC(=O)c1cn(CC(=O)Nc2ccc(C)c(C)c2)c2ccccc12 nan
16022830 23314 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 5.2 Cc1ccc(NC(=O)C2CCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)CC2)c(Cl)c1 nan
CHEMBL1332482 23314 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 5.2 Cc1ccc(NC(=O)C2CCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)CC2)c(Cl)c1 nan
4443607 23518 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 1 5 3.3 COc1cc2[nH]c(=S)n(Cc3ccc(F)cc3)c(=O)c2cc1OC nan
CHEMBL1334074 23518 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 1 5 3.3 COc1cc2[nH]c(=S)n(Cc3ccc(F)cc3)c(=O)c2cc1OC nan
3245441 23562 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 3.1 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc1c2c(nc3c1CCC3)CCC2 nan
CHEMBL1334367 23562 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 3.1 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc1c2c(nc3c1CCC3)CCC2 nan
16009378 23639 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 0 5 3.8 Cc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c(C)c1 nan
CHEMBL1335076 23639 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 0 5 3.8 Cc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c(C)c1 nan
135454500 23886 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 7 4.6 Cc1cc(-n2c(SCC(=O)Nc3ccc(F)c(F)c3)nc3nnc(C)c-3c2N)ccc1Cl nan
CHEMBL1337074 23886 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 7 4.6 Cc1cc(-n2c(SCC(=O)Nc3ccc(F)c(F)c3)nc3nnc(C)c-3c2N)ccc1Cl nan
16023881 23972 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 2 2 4.2 O=C(Nc1ccc(F)cc1F)c1cc2ccc3cccnc3c2[nH]1 nan
CHEMBL1337846 23972 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 2 2 4.2 O=C(Nc1ccc(F)cc1F)c1cc2ccc3cccnc3c2[nH]1 nan
3458131 24138 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 4 5.1 Cc1nc(SCc2ccc(F)cc2)c2oc3ccccc3c2n1 nan
CHEMBL1339257 24138 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 4 5.1 Cc1nc(SCc2ccc(F)cc2)c2oc3ccccc3c2n1 nan
3677224 24166 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 6 3.3 O=C(NCCc1ccccc1)c1cc(-c2ccncc2)nc2ccc(S(=O)(=O)N3CCOCC3)cc12 nan
CHEMBL1339543 24166 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 6 3.3 O=C(NCCc1ccccc1)c1cc(-c2ccncc2)nc2ccc(S(=O)(=O)N3CCOCC3)cc12 nan
4625935 24225 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 4 4.4 CC(=O)c1sc(NC(=O)c2ccc(F)cc2)nc1-c1ccccc1 nan
CHEMBL1340080 24225 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 4 4.4 CC(=O)c1sc(NC(=O)c2ccc(F)cc2)nc1-c1ccccc1 nan
1873236 24500 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 1 7 2.6 COC(=O)c1ccc2c(=O)n(Cc3ccc4c(c3)OCO4)c(=S)[nH]c2c1 nan
CHEMBL1342433 24500 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 1 7 2.6 COC(=O)c1ccc2c(=O)n(Cc3ccc4c(c3)OCO4)c(=S)[nH]c2c1 nan
1302080 24560 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 2 4 2.8 O=C(CCc1ccccc1)NC(=S)Nc1ccc2c(c1)C(=O)OC2 nan
CHEMBL1342849 24560 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 2 4 2.8 O=C(CCc1ccccc1)NC(=S)Nc1ccc2c(c1)C(=O)OC2 nan
3185654 24605 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 9 3 8 3.3 COc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCC1)c1ccc(N(C)C)cc1 nan
CHEMBL1343261 24605 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 9 3 8 3.3 COc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCC1)c1ccc(N(C)C)cc1 nan
1164441 24656 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 7 4.8 COc1ccc2nc(SCC(=O)Nc3ccc4sc(C)nc4c3)c(C#N)cc2c1 nan
CHEMBL1343720 24656 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 7 4.8 COc1ccc2nc(SCC(=O)Nc3ccc4sc(C)nc4c3)c(C#N)cc2c1 nan
653965 24681 5 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 4 3.8 Cc1cc(C)c2nc(SCC(=O)N3CCCCC3)c(C#N)cc2c1 nan
CHEMBL1343941 24681 5 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 4 3.8 Cc1cc(C)c2nc(SCC(=O)N3CCCCC3)c(C#N)cc2c1 nan
5068572 25147 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 6 3.1 COc1ccc(Cn2c(=S)[nH]c3cc(OC)c(OC)cc3c2=O)cc1 nan
CHEMBL1347842 25147 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 6 3.1 COc1ccc(Cn2c(=S)[nH]c3cc(OC)c(OC)cc3c2=O)cc1 nan
2992621 25192 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 4 3.0 COc1cccc2cc(C(=O)NCc3ccc(C)cc3)c(=O)oc12 nan
CHEMBL1348238 25192 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 4 3.0 COc1cccc2cc(C(=O)NCc3ccc(C)cc3)c(=O)oc12 nan
2785932 25268 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 0 0 5 1.4 Cn1c(=O)c2cc3ccc(Cl)cc3nc2n(C)c1=O nan
CHEMBL1348983 25268 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 0 0 5 1.4 Cn1c(=O)c2cc3ccc(Cl)cc3nc2n(C)c1=O nan
20929691 25293 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 3.0 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccco3)c2n1 nan
CHEMBL1349170 25293 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 3.0 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccco3)c2n1 nan
1261778 25525 11 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 3 1 3 5.6 Cc1cccc2c(C(=O)Nc3ccc(Br)cc3)cc(-c3ccccn3)nc12 nan
CHEMBL1351124 25525 11 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 3 1 3 5.6 Cc1cccc2c(C(=O)Nc3ccc(Br)cc3)cc(-c3ccccn3)nc12 nan
2309203 25528 7 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 2 4 4.3 O=C(NCCCCNC(=O)c1ccc(Br)s1)c1ccc(Br)s1 nan
CHEMBL1351160 25528 7 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 2 4 4.3 O=C(NCCCCNC(=O)c1ccc(Br)s1)c1ccc(Br)s1 nan
1945599 25661 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 6 3.7 COc1cc(C(=O)NC(=S)Nc2cccc3nc(C)ccc23)cc(OC)c1OC nan
CHEMBL1352289 25661 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 6 3.7 COc1cc(C(=O)NC(=S)Nc2cccc3nc(C)ccc23)cc(OC)c1OC nan
2345662 25770 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 1 6 2.8 COc1ccc(-c2nnc(NC(=O)C(C)C)s2)c(OC)c1 nan
CHEMBL1353144 25770 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 1 6 2.8 COc1ccc(-c2nnc(NC(=O)C(C)C)s2)c(OC)c1 nan
2588947 25806 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.2 COc1ccc2c(-c3ccccc3)cc(SCC(=O)NC(N)=O)nc2c1 nan
CHEMBL1353338 25806 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.2 COc1ccc2c(-c3ccccc3)cc(SCC(=O)NC(N)=O)nc2c1 nan
16024589 25940 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccccc3Cl)c2n1 nan
CHEMBL1354308 25940 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccccc3Cl)c2n1 nan
24981187 25948 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 7 0 7 2.0 CCOC(=O)C1CCN(C(=O)COC(=O)C2CCN(S(=O)(=O)c3ccc(C)c(C)c3)CC2)CC1 nan
CHEMBL1354340 25948 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 7 0 7 2.0 CCOC(=O)C1CCN(C(=O)COC(=O)C2CCN(S(=O)(=O)c3ccc(C)c(C)c3)CC2)CC1 nan
16015624 25978 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 6 5.8 Cc1ccccc1OCC(=O)Nc1ccc2nc(SCCOc3ccccc3)sc2c1 nan
CHEMBL1354759 25978 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 6 5.8 Cc1ccccc1OCC(=O)Nc1ccc2nc(SCCOc3ccccc3)sc2c1 nan
16022729 26036 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 2.5 Cc1noc(Cn2c(=O)c3ccccc3n(CC(=O)Nc3cc(Cl)ccc3C)c2=O)n1 nan
CHEMBL1355436 26036 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 2.5 Cc1noc(Cn2c(=O)c3ccccc3n(CC(=O)Nc3cc(Cl)ccc3C)c2=O)n1 nan
15989639 26039 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.4 COc1ccc(CCn2c(=O)c3ccccc3n(CC(=O)Nc3cccc(C)c3)c2=O)cc1OC nan
CHEMBL1355514 26039 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.4 COc1ccc(CCn2c(=O)c3ccccc3n(CC(=O)Nc3cccc(C)c3)c2=O)cc1OC nan
16023098 26044 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 1 5 4.1 Cc1nnc2c3ccccc3nc(Nc3ccc(F)cc3Cl)n12 nan
CHEMBL1355617 26044 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 1 5 4.1 Cc1nnc2c3ccccc3nc(Nc3ccc(F)cc3Cl)n12 nan
2150160 26045 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 6 4.2 COCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
CHEMBL1355622 26045 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 6 4.2 COCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
135546934 26050 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 3 3 7 4.3 Cc1cccc(NC(=O)c2sc3nc(-c4cc5ccc(O)cc5oc4=O)[nH]c(=O)c3c2C)c1 nan
CHEMBL1355684 26050 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 3 3 7 4.3 Cc1cccc(NC(=O)c2sc3nc(-c4cc5ccc(O)cc5oc4=O)[nH]c(=O)c3c2C)c1 nan
135419178 26071 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 2 5 4.8 CC(=O)Nc1ccc(/C=C/c2nc(-c3ccccc3O)n(-c3ccccc3)n2)cc1 nan
CHEMBL1355898 26071 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 2 5 4.8 CC(=O)Nc1ccc(/C=C/c2nc(-c3ccccc3O)n(-c3ccccc3)n2)cc1 nan
16017045 26116 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 0 6 4.8 CCC(C(=O)N1CCN(c2cccc(C)c2C)CC1)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1356499 26116 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 0 6 4.8 CCC(C(=O)N1CCN(c2cccc(C)c2C)CC1)n1nc(C)c2sc3ccccc3c2c1=O nan
15990110 26118 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 0 5 5.3 Cc1ccc(C)c(N2CCN(C(c3ccccc3)c3nnc(-c4ccccc4)o3)CC2)c1 nan
CHEMBL1356570 26118 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 0 5 5.3 Cc1ccc(C)c(N2CCN(C(c3ccccc3)c3nnc(-c4ccccc4)o3)CC2)c1 nan
5886984 26123 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 6.8 COc1c(Cl)cc(Cl)cc1/C=C(\C#N)c1nc(-c2ccc(Cl)cc2)cs1 nan
CHEMBL1356614 26123 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 6.8 COc1c(Cl)cc(Cl)cc1/C=C(\C#N)c1nc(-c2ccc(Cl)cc2)cs1 nan
16018240 26145 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 5.2 Cc1c(C(=O)NCc2ccc(N(C)C)cc2)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
CHEMBL1356884 26145 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 5.2 Cc1c(C(=O)NCc2ccc(N(C)C)cc2)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
2219490 26155 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 1 4 5.1 O=C(Cn1cc(C(=O)c2ccco2)c2ccccc21)Nc1ccccc1C(F)(F)F nan
CHEMBL1357026 26155 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 1 4 5.1 O=C(Cn1cc(C(=O)c2ccco2)c2ccccc21)Nc1ccccc1C(F)(F)F nan
16007510 26180 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 1 4 5.6 CCOc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
CHEMBL1357328 26180 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 1 4 5.6 CCOc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
16010573 26181 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 8 1 7 2.6 CCOc1ccccc1NC(=O)Cn1c(=O)n(CCC(C)C)c(=O)c2cccnc21 nan
CHEMBL1357333 26181 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 8 1 7 2.6 CCOc1ccccc1NC(=O)Cn1c(=O)n(CCC(C)C)c(=O)c2cccnc21 nan
7533493 26187 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 6 4.1 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(F)ccc3F)o2)cc1 nan
CHEMBL1357469 26187 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 6 4.1 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(F)ccc3F)o2)cc1 nan
16030313 26211 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.1 Cc1ccccc1C(=O)Nc1ccc(OCc2cc(=O)n3cccc(C)c3n2)cc1 nan
CHEMBL1357868 26211 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.1 Cc1ccccc1C(=O)Nc1ccc(OCc2cc(=O)n3cccc(C)c3n2)cc1 nan
7244606 26214 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 0 7 2.9 C#CCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(OC)c(OC)cc21 nan
CHEMBL1357945 26214 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 0 7 2.9 C#CCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(OC)c(OC)cc21 nan
16018859 26218 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 4.1 O=C(CCCn1c(=O)c2cccn2c2cccnc21)Nc1ccccc1C(F)(F)F nan
CHEMBL1357984 26218 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 4.1 O=C(CCCn1c(=O)c2cccn2c2cccnc21)Nc1ccccc1C(F)(F)F nan
16009434 26222 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 7 1 7 3.4 O=C(COc1ccccc1)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1358022 26222 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 7 1 7 3.4 O=C(COc1ccccc1)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
15987969 26298 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 1 4 4.1 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)CCC(=O)Nc3cccc(CC)c3)c21 nan
CHEMBL1358851 26298 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 1 4 4.1 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)CCC(=O)Nc3cccc(CC)c3)c21 nan
3799752 26299 8 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 2.4 COc1ccc(OC)c(N/C=C2/C(=O)NC(=S)N(Cc3ccccc3)C2=O)c1 nan
CHEMBL1358861 26299 8 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 2.4 COc1ccc(OC)c(N/C=C2/C(=O)NC(=S)N(Cc3ccccc3)C2=O)c1 nan
7210861 26376 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 2 5 3.6 CCn1c(SCC(=O)Nc2ccccc2)nc2c([nH]c3ccccc32)c1=O nan
CHEMBL1359450 26376 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 2 5 3.6 CCn1c(SCC(=O)Nc2ccccc2)nc2c([nH]c3ccccc32)c1=O nan
1818953 26536 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 0 6 5.7 C=C(C)Cn1c(SCC(=O)c2ccc(Br)cc2)nc2sc3c(c2c1=O)CCCC3 nan
CHEMBL1360901 26536 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 0 6 5.7 C=C(C)Cn1c(SCC(=O)c2ccc(Br)cc2)nc2sc3c(c2c1=O)CCCC3 nan
16022921 26598 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.7 CCOc1ccccc1CNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)CC1 nan
CHEMBL1361507 26598 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.7 CCOc1ccccc1CNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)CC1 nan
4329717 26611 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 2 3 4.2 CC(NC(=O)c1cc(O)nc2ccc(Br)cc12)c1ccccc1 nan
CHEMBL1361599 26611 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 2 3 4.2 CC(NC(=O)c1cc(O)nc2ccc(Br)cc12)c1ccccc1 nan
3475073 26649 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 2 5.4 Cc1cc2ccccc2n1CCNC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
CHEMBL1361903 26649 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 2 5.4 Cc1cc2ccccc2n1CCNC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
16022126 26678 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 5 4.5 COc1cc(OC)c(NC(=O)c2c(N3CCCC3=O)c3cc(C)ccc3n2C)cc1Cl nan
CHEMBL1362140 26678 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 5 4.5 COc1cc(OC)c(NC(=O)c2c(N3CCCC3=O)c3cc(C)ccc3n2C)cc1Cl nan
1984900 26703 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 531 8 1 7 5.0 CCOc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3cccs3)cc2)cc1 nan
CHEMBL1362375 26703 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 531 8 1 7 5.0 CCOc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3cccs3)cc2)cc1 nan
6471827 26734 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 9 2.4 Cc1nnc(NC(=O)C(C)Sc2nnc(-c3ccco3)n2C)s1 nan
CHEMBL1362583 26734 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 9 2.4 Cc1nnc(NC(=O)C(C)Sc2nnc(-c3ccco3)n2C)s1 nan
7693885 26747 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 4 1 4 3.9 COc1ccc(C(=O)Nc2cc(-c3ccc(C)cc3)no2)cc1 nan
CHEMBL1362677 26747 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 4 1 4 3.9 COc1ccc(C(=O)Nc2cc(-c3ccc(C)cc3)no2)cc1 nan
16019393 26758 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 8 4.0 CCCCNc1nc2c(S(=O)(=O)c3ccc(Cl)cc3)nnn2c2ccsc12 nan
CHEMBL1362800 26758 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 8 4.0 CCCCNc1nc2c(S(=O)(=O)c3ccc(Cl)cc3)nnn2c2ccsc12 nan
22334175 26776 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 548 10 2 10 2.8 COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cc(OC)c(OC)c(OC)c3)c3ccccc3c2=O)cc1OC nan
CHEMBL1362992 26776 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 548 10 2 10 2.8 COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cc(OC)c(OC)c(OC)c3)c3ccccc3c2=O)cc1OC nan
645413 26788 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 5 3.4 Cc1cc(C(F)F)n2nc(C(=O)Nc3ccccc3Br)nc2n1 nan
CHEMBL1363101 26788 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 5 3.4 Cc1cc(C(F)F)n2nc(C(=O)Nc3ccccc3Br)nc2n1 nan
16024545 26798 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 4.8 Cc1ccc(C)c(NC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)c1 nan
CHEMBL1363144 26798 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 4.8 Cc1ccc(C)c(NC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)c1 nan
4447999 26834 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 2 6 4.6 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCC(=O)NC2CCCCC2)cc1C nan
CHEMBL1363483 26834 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 2 6 4.6 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCC(=O)NC2CCCCC2)cc1C nan
16030946 26884 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 4.1 COc1ccc(NC(=O)CSc2ccc3nc(-c4ccccc4)cn3n2)cc1OC nan
CHEMBL1363950 26884 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 4.1 COc1ccc(NC(=O)CSc2ccc3nc(-c4ccccc4)cn3n2)cc1OC nan
1960168 26942 9 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 2 0 5 4.4 Cc1ccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccc(F)cc2)cc1 nan
CHEMBL1364491 26942 9 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 2 0 5 4.4 Cc1ccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccc(F)cc2)cc1 nan
1258567 27135 17 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.5 COc1ccc(-c2cc(-c3ccccc3)nc(SCC(=O)Nc3nccs3)c2C#N)cc1 nan
CHEMBL1366086 27135 17 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.5 COc1ccc(-c2cc(-c3ccccc3)nc(SCC(=O)Nc3nccs3)c2C#N)cc1 nan
5726342 27169 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 3 3.8 CN1C(=O)C(O)=C(C(=O)c2ccc(Br)cc2)C1c1ccc(F)cc1 nan
CHEMBL1366379 27169 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 3 3.8 CN1C(=O)C(O)=C(C(=O)c2ccc(Br)cc2)C1c1ccc(F)cc1 nan
16015810 27183 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 5 5.3 COc1ccc(OCC(=O)Nc2cccc(-c3nc4ccccc4s3)c2C)cc1 nan
CHEMBL1366460 27183 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 5 5.3 COc1ccc(OCC(=O)Nc2cccc(-c3nc4ccccc4s3)c2C)cc1 nan
5204153 27204 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 5 2 7 1.3 CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3ccc4c(c3)C(=O)NC4=O)cc2)CC1 nan
CHEMBL1366674 27204 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 5 2 7 1.3 CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3ccc4c(c3)C(=O)NC4=O)cc2)CC1 nan
16015685 27242 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 5.5 Cc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc54)sc3c2)cc1 nan
CHEMBL1367053 27242 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 5.5 Cc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc54)sc3c2)cc1 nan
561651 27355 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 0 3 4.6 c1ccc(C2=NN(c3ccccc3)C(c3ccco3)C2)cc1 nan
CHEMBL1367925 27355 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 0 3 4.6 c1ccc(C2=NN(c3ccccc3)C(c3ccco3)C2)cc1 nan
16022119 27584 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 0 8 3.9 COc1ccc2c(c1)c1c(c(=O)n(-c3ccc(OC)c(OC)c3)c(=O)n1Cc1ccc(F)cc1)n2C nan
CHEMBL1369667 27584 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 0 8 3.9 COc1ccc2c(c1)c1c(c(=O)n(-c3ccc(OC)c(OC)c3)c(=O)n1Cc1ccc(F)cc1)n2C nan
16024643 27614 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 5 3.9 CCc1ccc(C(=O)c2cn(CC(=O)NCCc3ccccc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1369852 27614 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 5 3.9 CCc1ccc(C(=O)c2cn(CC(=O)NCCc3ccccc3)c3nc(C)ccc3c2=O)cc1 nan
16018703 27659 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 0 6 3.4 Cc1ccc(Cl)cc1N1CCN(C(=O)CCn2c(=O)c3cccn3c3cccnc32)CC1 nan
CHEMBL1370112 27659 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 0 6 3.4 Cc1ccc(Cl)cc1N1CCN(C(=O)CCn2c(=O)c3cccn3c3cccnc32)CC1 nan
16017844 27736 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 6 1.6 COc1cccc(-n2ccn(CC(=O)NCc3ccc(C)cc3)c(=O)c2=O)c1 nan
CHEMBL1370655 27736 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 6 1.6 COc1cccc(-n2ccn(CC(=O)NCc3ccc(C)cc3)c(=O)c2=O)c1 nan
2053979 27751 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 0 5 4.0 CCN(C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1)C1CCCCC1 nan
CHEMBL1370734 27751 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 0 5 4.0 CCN(C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1)C1CCCCC1 nan
2999996 27778 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 3 0 9 2.9 O=C(OCc1cc(=O)n2c(n1)sc1ccccc12)c1ccc2c(=O)n3c(nc2c1)CCC3 nan
CHEMBL1370976 27778 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 3 0 9 2.9 O=C(OCc1cc(=O)n2c(n1)sc1ccccc12)c1ccc2c(=O)n3c(nc2c1)CCC3 nan
2212806 27832 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 2 4 5.1 Cc1cccc(NC(=O)c2cc(NC(=O)c3ccco3)ccc2N2CCCCC2)c1 nan
CHEMBL1371405 27832 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 2 4 5.1 Cc1cccc(NC(=O)c2cc(NC(=O)c3ccco3)ccc2N2CCCCC2)c1 nan
4069120 27850 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 5 4.7 COc1ccc(OC)c(NC(=O)c2oc(=O)c3ccccc3c2-c2ccccc2)c1 nan
CHEMBL1371548 27850 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 5 4.7 COc1ccc(OC)c(NC(=O)c2oc(=O)c3ccccc3c2-c2ccccc2)c1 nan
862401 27863 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 4 3.7 COc1ccc2nc(SCC(=O)NC3CCCC3)c(C)cc2c1 nan
CHEMBL1371650 27863 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 4 3.7 COc1ccc2nc(SCC(=O)NC3CCCC3)c(C)cc2c1 nan
941550 27867 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 6 3.4 COc1ccc2nc(O)c(COC(=O)c3cccs3)cc2c1 nan
CHEMBL1371690 27867 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 6 3.4 COc1ccc2nc(O)c(COC(=O)c3cccs3)cc2c1 nan
648869 27988 5 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 0 5 3.9 CCOc1ccc2cc(C#N)c(SCC(=O)N3CCC(C)CC3)nc2c1 nan
CHEMBL1372547 27988 5 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 0 5 3.9 CCOc1ccc2cc(C#N)c(SCC(=O)N3CCC(C)CC3)nc2c1 nan
664361 28035 12 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1nc(SCC(=O)Nc2ccccc2)c2oc3ccccc3c2n1 nan
CHEMBL1372818 28035 12 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1nc(SCC(=O)Nc2ccccc2)c2oc3ccccc3c2n1 nan
2404728 28165 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.4 O=C(COC(=O)c1ccc(Cl)cc1O)NC(=O)C1CCCCC1 nan
CHEMBL1373640 28165 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.4 O=C(COC(=O)c1ccc(Cl)cc1O)NC(=O)C1CCCCC1 nan
711468 28202 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 1 1 3 3.3 Cc1cc(-c2cccc(Br)c2)c(C#N)c(N)n1 nan
CHEMBL1373906 28202 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 1 1 3 3.3 Cc1cc(-c2cccc(Br)c2)c(C#N)c(N)n1 nan
660358 28244 21 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 8 4.8 CCOC(=O)c1sc(NC(=O)CSc2nc3c(cc2C#N)CCCCCC3)c(C#N)c1C nan
CHEMBL1374224 28244 21 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 8 4.8 CCOC(=O)c1sc(NC(=O)CSc2nc3c(cc2C#N)CCCCCC3)c(C#N)c1C nan
848636 28289 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 6 5.1 Cc1sc2ncnc(Sc3nc4ccccc4s3)c2c1C nan
CHEMBL1374559 28289 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 6 5.1 Cc1sc2ncnc(Sc3nc4ccccc4s3)c2c1C nan
22330687 28312 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 1 8 4.3 COc1ccc(C)cc1NC(=O)c1sc2ncnc(N3CCN(c4ccccn4)CC3)c2c1C nan
CHEMBL1374703 28312 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 1 8 4.3 COc1ccc(C)cc1NC(=O)c1sc2ncnc(N3CCN(c4ccccn4)CC3)c2c1C nan
16421351 28339 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1OC nan
5513687 28339 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1OC nan
CHEMBL1374848 28339 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1OC nan
2113664 28466 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 0 8 4.2 CCc1cc2c(SCC(=O)C(C#N)=C3N(C)c4ccccc4N3C)ncnc2s1 nan
CHEMBL1375768 28466 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 0 8 4.2 CCc1cc2c(SCC(=O)C(C#N)=C3N(C)c4ccccc4N3C)ncnc2s1 nan
1049792 28517 24 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 0 5 5.0 COc1ccc(-c2cc(-c3ccc(OC)cc3)c(C#N)c(SC)n2)cc1 nan
CHEMBL1376368 28517 24 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 0 5 5.0 COc1ccc(-c2cc(-c3ccc(OC)cc3)c(C#N)c(SC)n2)cc1 nan
3141909 28522 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 2 0 4 3.0 Cc1cccc2cc(C#N)c(SCC#N)nc12 nan
CHEMBL1376381 28522 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 2 0 4 3.0 Cc1cccc2cc(C#N)c(SCC#N)nc12 nan
1086373 28575 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 1 6 3.6 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCc3ccco3)n2)c1 nan
CHEMBL1376846 28575 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 1 6 3.6 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCc3ccco3)n2)c1 nan
16024493 28664 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 5 3.3 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)NCc3ccccc3)c2n1 nan
CHEMBL1377756 28664 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 5 3.3 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)NCc3ccccc3)c2n1 nan
16018882 28670 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 9 1 5 4.2 CCOc1ccc(N(CC)S(=O)(=O)N2CCCC(C(=O)Nc3ccc(OC)c(Cl)c3)C2)cc1 nan
CHEMBL1377806 28670 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 9 1 5 4.2 CCOc1ccc(N(CC)S(=O)(=O)N2CCCC(C(=O)Nc3ccc(OC)c(Cl)c3)C2)cc1 nan
2426511 28738 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 240 0 0 4 2.7 Cc1cc(=O)n2c(sc3ccccc32)c1C#N nan
CHEMBL1378393 28738 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 240 0 0 4 2.7 Cc1cc(=O)n2c(sc3ccccc32)c1C#N nan
2060585 28753 68 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 1 1 2 1.4 O=C(c1ccccc1Cl)N1CCNCC1 nan
CHEMBL1378602 28753 68 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 1 1 2 1.4 O=C(c1ccccc1Cl)N1CCNCC1 nan
54680441 28827 20 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 3 4 2.6 O=C(NCc1ccccc1)c1c(O)nc2ccccc2c1O nan
CHEMBL1379243 28827 20 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 3 4 2.6 O=C(NCc1ccccc1)c1c(O)nc2ccccc2c1O nan
7502810 28885 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 3.9 Cc1cc(NC(=O)CSc2ccc(-c3ccc(Br)cc3)nn2)no1 nan
CHEMBL1379696 28885 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 3.9 Cc1cc(NC(=O)CSc2ccc(-c3ccc(Br)cc3)nn2)no1 nan
663350 28945 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 0 9 2.9 COc1cc(OC)c(-c2nn3c(-c4cccnc4)nnc3s2)cc1OC nan
CHEMBL1380292 28945 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 0 9 2.9 COc1cc(OC)c(-c2nn3c(-c4cccnc4)nnc3s2)cc1OC nan
551775 29039 13 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 0 5 4.0 CCN(CC)C(=O)CSc1nc(C)cc(-c2cccs2)c1C#N nan
CHEMBL1380940 29039 13 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 0 5 4.0 CCN(CC)C(=O)CSc1nc(C)cc(-c2cccs2)c1C#N nan
6470016 29175 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 2 2 3.4 CC1=C(C)CC(C(=O)NCc2cccc(Cl)c2)C(C(=O)O)C1 nan
CHEMBL1382205 29175 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 2 2 3.4 CC1=C(C)CC(C(=O)NCc2cccc(Cl)c2)C(C(=O)O)C1 nan
4908628 29184 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 4 3.4 Cc1ccc(S(=O)(=O)N(C)Cc2cc3cc(C)ccc3nc2O)cc1 nan
CHEMBL1382276 29184 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 4 3.4 Cc1ccc(S(=O)(=O)N(C)Cc2cc3cc(C)ccc3nc2O)cc1 nan
1450725 29187 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 0 7 1.8 N#Cc1cc2cc3c(cc2nc1SCC(=O)N1CCOCC1)OCO3 nan
CHEMBL1382288 29187 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 0 7 1.8 N#Cc1cc2cc3c(cc2nc1SCC(=O)N1CCOCC1)OCO3 nan
5155717 29344 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 2 5 2.1 NS(=O)(=O)c1ccc(CCn2c(=S)[nH]c3ccc(F)cc3c2=O)cc1 nan
CHEMBL1383680 29344 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 2 5 2.1 NS(=O)(=O)c1ccc(CCn2c(=S)[nH]c3ccc(F)cc3c2=O)cc1 nan
1271521 29538 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 4.9 O=C(Nc1ccc(-c2noc(-c3ccccc3F)n2)cc1)c1cccs1 nan
CHEMBL1385411 29538 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 4.9 O=C(Nc1ccc(-c2noc(-c3ccccc3F)n2)cc1)c1cccs1 nan
1604314 29676 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 6 3.6 CCOC(=O)C1=C(c2ccccc2)O/C(=C(/C(=O)OC)C(F)(F)F)S1 nan
CHEMBL1386476 29676 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 6 3.6 CCOC(=O)C1=C(c2ccccc2)O/C(=C(/C(=O)OC)C(F)(F)F)S1 nan
2815677 29692 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 3 0 6 1.5 CCOC(=O)c1cn2nc(N3CCCC3)ccc2n1 nan
CHEMBL1386622 29692 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 3 0 6 1.5 CCOC(=O)c1cn2nc(N3CCCC3)ccc2n1 nan
979520 29815 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 9 2 4 4.5 COc1cc(CNCc2ccccc2Cl)ccc1OCC(=O)NC1CCCCC1 nan
CHEMBL1387627 29815 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 9 2 4 4.5 COc1cc(CNCc2ccccc2Cl)ccc1OCC(=O)NC1CCCCC1 nan
855469 29851 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 3.4 Cc1cc(NC(=O)CSc2nc3c(C)cccc3cc2C#N)no1 nan
CHEMBL1387916 29851 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 3.4 Cc1cc(NC(=O)CSc2nc3c(C)cccc3cc2C#N)no1 nan
1026561 29862 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 2 3 4.5 CCOc1ccc(Br)cc1C(=O)Nc1ccc(C(=O)NCC(C)C)cc1 nan
CHEMBL1388002 29862 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 2 3 4.5 CCOc1ccc(Br)cc1C(=O)Nc1ccc(C(=O)NCC(C)C)cc1 nan
2372910 29907 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 2 0 5 3.3 c1ccc(-c2cc(-c3nnco3)c3ccccc3n2)nc1 nan
CHEMBL1388328 29907 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 2 0 5 3.3 c1ccc(-c2cc(-c3nnco3)c3ccccc3n2)nc1 nan
4909035 30147 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 5 4.0 Cc1cccc(-c2nc3c(c(SCC(=O)N4CCCC4)n2)COC(C)(C)C3)c1 nan
CHEMBL1390262 30147 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 5 4.0 Cc1cccc(-c2nc3c(c(SCC(=O)N4CCCC4)n2)COC(C)(C)C3)c1 nan
20969169 30174 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 1 7 4.1 COc1ccc(Cl)cc1NC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C nan
CHEMBL1390480 30174 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 1 7 4.1 COc1ccc(Cl)cc1NC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C nan
4688970 30181 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 1 6 4.2 Cc1nc(N2CCOCC2)c2c(C)c(C(=O)Nc3ccc(F)cc3Cl)sc2n1 nan
CHEMBL1390558 30181 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 1 6 4.2 Cc1nc(N2CCOCC2)c2c(C)c(C(=O)Nc3ccc(F)cc3Cl)sc2n1 nan
6621188 30185 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 6 2 4 2.3 CCc1ccc(NC(=O)CNC(=O)Cn2ccc3ccccc3c2=O)cc1 nan
CHEMBL1390571 30185 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 6 2 4 2.3 CCc1ccc(NC(=O)CNC(=O)Cn2ccc3ccccc3c2=O)cc1 nan
24687564 30322 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 2 7 4.0 CCOC(=O)c1c(NC(=O)COc2ccccc2C#N)sc2c1CC(C)(C)NC2(C)C nan
CHEMBL1391818 30322 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 2 7 4.0 CCOC(=O)c1c(NC(=O)COc2ccccc2C#N)sc2c1CC(C)(C)NC2(C)C nan
8030390 30419 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 3.1 Cc1c(C)c2ccc(OCC(=O)Nc3ccccn3)c(C)c2oc1=O nan
CHEMBL1392611 30419 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 3.1 Cc1c(C)c2ccc(OCC(=O)Nc3ccccn3)c(C)c2oc1=O nan
649622 30490 3 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 0 7 2.5 CCOC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 nan
CHEMBL1393221 30490 3 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 0 7 2.5 CCOC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 nan
16024685 30588 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 5 1 5 5.2 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)Nc3ccccc3C(F)(F)F)c2n1 nan
CHEMBL1394039 30588 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 5 1 5 5.2 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)Nc3ccccc3C(F)(F)F)c2n1 nan
3844740 30590 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 3 7 3.8 COc1ccc(C2C=C(c3ccc(Cl)cc3)Nc3nc(NC(=O)CCC(=O)O)nn32)cc1 nan
CHEMBL1394052 30590 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 3 7 3.8 COc1ccc(C2C=C(c3ccc(Cl)cc3)Nc3nc(NC(=O)CCC(=O)O)nn32)cc1 nan
16024945 30602 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 1 4 4.8 O=C(Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)nnn2C1CCCC1 nan
CHEMBL1394171 30602 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 1 4 4.8 O=C(Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)nnn2C1CCCC1 nan
2136700 30609 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 3.8 Cc1ccccc1NC(=O)Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2ccccc21 nan
CHEMBL1394236 30609 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 3.8 Cc1ccccc1NC(=O)Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2ccccc21 nan
16017140 30647 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 5 5.0 Cc1ccc(C)c(NC(=O)CCCn2nc(C)c3sc4ccccc4c3c2=O)c1 nan
CHEMBL1394852 30647 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 5 5.0 Cc1ccc(C)c(NC(=O)CCCn2nc(C)c3sc4ccccc4c3c2=O)c1 nan
16022416 30648 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 7 4.6 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCCc4ccccc4)cc3nc2s1 nan
CHEMBL1394859 30648 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 7 4.6 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCCc4ccccc4)cc3nc2s1 nan
16030605 30655 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 0 5 5.3 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)N1CCCc2ccccc21 nan
CHEMBL1394911 30655 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 0 5 5.3 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)N1CCCc2ccccc21 nan
16034772 30691 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 1 6 4.6 Cc1nn(CCCC(=O)Nc2cccc(C(F)(F)F)c2)c(=O)c2nn(-c3ccccc3)c(C)c12 nan
CHEMBL1395185 30691 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 1 6 4.6 Cc1nn(CCCC(=O)Nc2cccc(C(F)(F)F)c2)c(=O)c2nn(-c3ccccc3)c(C)c12 nan
2007143 30695 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 1.9 CCOC(=O)CNC(=O)c1ccc(-c2nn(C)c(=O)c3ccccc23)cc1 nan
CHEMBL1395237 30695 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 1.9 CCOC(=O)CNC(=O)c1ccc(-c2nn(C)c(=O)c3ccccc23)cc1 nan
16019606 30696 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 4.7 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccccc2Cl)c2sccc23)cc1 nan
CHEMBL1395245 30696 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 4.7 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccccc2Cl)c2sccc23)cc1 nan
16018799 30698 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 1 5 3.2 CCc1cccc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)c1 nan
CHEMBL1395272 30698 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 1 5 3.2 CCc1cccc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)c1 nan
15987986 30717 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 6 1 4 4.0 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)CCC(=O)Nc3ccc(C)c(F)c3)c21 nan
CHEMBL1395557 30717 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 6 1 4 4.0 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)CCC(=O)Nc3ccc(C)c(F)c3)c21 nan
16009626 30731 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 2 3 5.7 Cc1cc(C)cc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)c1 nan
CHEMBL1395778 30731 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 2 3 5.7 Cc1cc(C)cc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)c1 nan
16017553 30754 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 6 2.7 O=C(Nc1nnc(S(=O)(=O)N2CCCCC2)s1)c1ccccc1Br nan
CHEMBL1396131 30754 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 6 2.7 O=C(Nc1nnc(S(=O)(=O)N2CCCCC2)s1)c1ccccc1Br nan
16033012 30779 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 4 0 7 3.3 O=C(Cn1c(=O)n2nc(-c3cccc(F)c3)nc2c2ccccc21)N1CCN(c2ccccc2F)CC1 nan
CHEMBL1396543 30779 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 4 0 7 3.3 O=C(Cn1c(=O)n2nc(-c3cccc(F)c3)nc2c2ccccc21)N1CCN(c2ccccc2F)CC1 nan
15989006 30786 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 8 3.5 O=C(CCn1c(=O)c2sccc2n(Cc2ccc(F)cc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1396634 30786 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 8 3.5 O=C(CCn1c(=O)c2sccc2n(Cc2ccc(F)cc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
16009460 30809 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 3.6 COc1ccc(C(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1OC nan
CHEMBL1396932 30809 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 3.6 COc1ccc(C(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1OC nan
3408184 30820 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 5 5.8 CCOc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
CHEMBL1397049 30820 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 5 5.8 CCOc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
4345038 30825 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 3 5.2 CN(Cc1ccccc1)S(=O)(=O)c1ccc(F)c(C(=O)Nc2cccc(Cl)c2Cl)c1 nan
CHEMBL1397130 30825 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 3 5.2 CN(Cc1ccccc1)S(=O)(=O)c1ccc(F)c(C(=O)Nc2cccc(Cl)c2Cl)c1 nan
16017005 30827 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 4.9 CCOc1ccc(NC(=O)C(=O)c2cc(C)n(-c3cc(C)cc(C)c3)c2C)cc1 nan
CHEMBL1397170 30827 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 4.9 CCOc1ccc(NC(=O)C(=O)c2cc(C)n(-c3cc(C)cc(C)c3)c2C)cc1 nan
16009843 30889 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 1 6 3.4 O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
CHEMBL1398005 30889 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 1 6 3.4 O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
15988021 30905 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 514 12 2 10 1.0 COCCNC(=O)CCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)Nc2ccccc2OC)c1=O nan
CHEMBL1398191 30905 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 514 12 2 10 1.0 COCCNC(=O)CCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)Nc2ccccc2OC)c1=O nan
2288826 31088 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 3 4 0.6 O=C1NC(=O)C(=CNc2cc(F)cc(F)c2)C(=O)N1 nan
CHEMBL1400030 31088 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 3 4 0.6 O=C1NC(=O)C(=CNc2cc(F)cc(F)c2)C(=O)N1 nan
16009302 31172 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.7 Cn1c2ccccc2c2cnn(CC(=O)Nc3ccccc3F)c(=O)c21 nan
CHEMBL1400803 31172 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.7 Cn1c2ccccc2c2cnn(CC(=O)Nc3ccccc3F)c(=O)c21 nan
16010052 31186 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 5 4.9 COc1ccc(CCNC(=O)Cn2c(-c3cccs3)cc3cc(F)ccc32)cc1OC nan
CHEMBL1400938 31186 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 5 4.9 COc1ccc(CCNC(=O)Cn2c(-c3cccs3)cc3cc(F)ccc32)cc1OC nan
16022925 31327 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 0 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)N(C)Cc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1402121 31327 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 0 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)N(C)Cc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
3238641 31375 37 None -354 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 5 1 3 3.0 COc1ccc(OCc2cccc(C(=O)O)c2)cc1 nan
CHEMBL1402510 31375 37 None -354 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 5 1 3 3.0 COc1ccc(OCc2cccc(C(=O)O)c2)cc1 nan
24792811 31386 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 4 0 5 4.4 Cc1cccc(N2CCN(c3ccc4cc(S(=O)(=O)N5CCCCC5)ccc4n3)CC2C)c1 nan
CHEMBL1402620 31386 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 4 0 5 4.4 Cc1cccc(N2CCN(c3ccc4cc(S(=O)(=O)N5CCCCC5)ccc4n3)CC2C)c1 nan
13020032 31422 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 5 2.9 COc1ccc(C[C@H]2c3cc(O)c(OC)cc3CC[N+]2(C)[O-])cc1O nan
CHEMBL1402907 31422 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 5 2.9 COc1ccc(C[C@H]2c3cc(O)c(OC)cc3CC[N+]2(C)[O-])cc1O nan
3456065 31426 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 4 4.8 Oc1nnc(Cc2ccc(-c3ccc(Cl)cc3)o2)c2ccccc12 nan
CHEMBL1402979 31426 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 4 4.8 Oc1nnc(Cc2ccc(-c3ccc(Cl)cc3)o2)c2ccccc12 nan
807671 31463 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 2 2 4 2.7 Cc1nc(NC(=O)c2ccccc2O)sc1C nan
CHEMBL1403354 31463 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 2 2 4 2.7 Cc1nc(NC(=O)c2ccccc2O)sc1C nan
24979173 31503 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 8 1 6 3.2 COc1ccccc1NC(=O)COC(=O)c1ccccc1SCC(=O)N1CCCC1 nan
CHEMBL1403792 31503 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 8 1 6 3.2 COc1ccccc1NC(=O)COC(=O)c1ccccc1SCC(=O)N1CCCC1 nan
1300573 31513 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 4 4.7 Cc1cccc(NC(=O)Cn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)c1 nan
CHEMBL1403862 31513 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 4 4.7 Cc1cccc(NC(=O)Cn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)c1 nan
3176404 31563 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 5 2 3 3.9 Cc1cccc(CCNCc2cc3cccc(C)c3nc2O)c1 nan
CHEMBL1404217 31563 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 5 2 3 3.9 Cc1cccc(CCNCc2cc3cccc(C)c3nc2O)c1 nan
2941406 31620 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 1 2 5 4.2 Cc1c(C#N)c(N)nc2c3c(sc12)NC(=O)CC3c1ccc(Cl)cc1 nan
CHEMBL1404915 31620 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 1 2 5 4.2 Cc1c(C#N)c(N)nc2c3c(sc12)NC(=O)CC3c1ccc(Cl)cc1 nan
663707 31705 15 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 4 4.8 Fc1ccc(CSc2ncnc3c2oc2ccccc23)cc1 nan
CHEMBL1405769 31705 15 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 4 4.8 Fc1ccc(CSc2ncnc3c2oc2ccccc23)cc1 nan
3207570 31714 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 5 3.1 CCc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
CHEMBL1405871 31714 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 5 3.1 CCc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
2102520 31869 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 6 1 7 5.0 COc1cc(C(=O)Nc2nc3ccc(C)cc3s2)ccc1OCc1c(C)noc1C nan
CHEMBL1407262 31869 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 6 1 7 5.0 COc1cc(C(=O)Nc2nc3ccc(C)cc3s2)ccc1OCc1c(C)noc1C nan
672442 31954 15 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 5 3.3 N#Cc1c(N)nc(N2CCCC2)c(C#N)c1-c1ccc(Cl)cc1 nan
CHEMBL1407760 31954 15 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 5 3.3 N#Cc1c(N)nc(N2CCCC2)c(C#N)c1-c1ccc(Cl)cc1 nan
15989447 31965 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 8 1 5 4.1 O=C(CCCn1c(=O)c2ccccc2n(Cc2cccc(F)c2)c1=O)NCc1ccccc1Cl nan
CHEMBL1407901 31965 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 8 1 5 4.1 O=C(CCCn1c(=O)c2ccccc2n(Cc2cccc(F)c2)c1=O)NCc1ccccc1Cl nan
5524322 32001 18 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 4.5 CSc1nsc(/C=C/Nc2cccc(Cl)c2)c1C#N nan
CHEMBL1408147 32001 18 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 4.5 CSc1nsc(/C=C/Nc2cccc(Cl)c2)c1C#N nan
135454349 32085 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 2 6 2.6 CCc1ccc(N2CC(=O)C(c3nc(O)c4ccccc4n3)=C2N)cc1 nan
CHEMBL1408793 32085 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 2 6 2.6 CCc1ccc(N2CC(=O)C(c3nc(O)c4ccccc4n3)=C2N)cc1 nan
16012616 32135 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 0 10 3.5 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccccc5F)s4)c3nc12 nan
CHEMBL1409190 32135 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 0 10 3.5 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccccc5F)s4)c3nc12 nan
16026074 32192 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 4 1 4 4.1 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccccc2C)CC1 nan
CHEMBL1409660 32192 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 4 1 4 4.1 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccccc2C)CC1 nan
5294544 32201 16 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 1 1 4 2.4 CCn1c(=S)[nH]c2nc3c(cc2c1=O)CCCC3 nan
CHEMBL1409738 32201 16 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 1 1 4 2.4 CCn1c(=S)[nH]c2nc3c(cc2c1=O)CCCC3 nan
3208202 32243 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 3 7 3.3 CCc1cc2c(C)ccc(C)c2nc1SCC(=O)Nc1cnc(O)nc1O nan
CHEMBL1410014 32243 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 3 7 3.3 CCc1cc2c(C)ccc(C)c2nc1SCC(=O)Nc1cnc(O)nc1O nan
2136000 32252 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.0 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
CHEMBL1410088 32252 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.0 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
2056596 32366 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 2 5 2.6 CCn1ncc(Br)c1C(=O)Nc1sc2c(c1C(N)=O)CCC2 nan
CHEMBL1411085 32366 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 2 5 2.6 CCn1ncc(Br)c1C(=O)Nc1sc2c(c1C(N)=O)CCC2 nan
15988949 32380 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 2 7 4.5 Cc1ccc(NC(=O)Cn2c(=O)n(CCCCCC(=O)NCc3ccc(F)cc3)c(=O)c3sccc32)cc1C nan
CHEMBL1411183 32380 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 2 7 4.5 Cc1ccc(NC(=O)Cn2c(=O)n(CCCCCC(=O)NCc3ccc(F)cc3)c(=O)c3sccc32)cc1C nan
4390376 32409 4 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 6 3.7 COc1ccc(-c2csc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)n2)cc1 nan
CHEMBL1411409 32409 4 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 6 3.7 COc1ccc(-c2csc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)n2)cc1 nan
627327 32469 34 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 1 0 3 3.6 O=c1oc(-c2ccc(Br)cc2)nc2ccccc12 nan
CHEMBL1411919 32469 34 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 1 0 3 3.6 O=c1oc(-c2ccc(Br)cc2)nc2ccccc12 nan
16017002 32507 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 6 1.8 CCOc1ccc(CNC(=O)C(C)n2ncn3cccc3c2=O)cc1 nan
CHEMBL1412238 32507 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 6 1.8 CCOc1ccc(CNC(=O)C(C)n2ncn3cccc3c2=O)cc1 nan
16026072 32556 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 5 4.2 CCOc1ccccc1CNC(=O)C1CCN(C2=NS(=O)(=O)C(c3ccc(C)c(C)c3)=C2C)CC1 nan
CHEMBL1412601 32556 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 5 4.2 CCOc1ccccc1CNC(=O)C1CCN(C2=NS(=O)(=O)C(c3ccc(C)c(C)c3)=C2C)CC1 nan
646655 32567 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 2.8 Cc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
CHEMBL1412670 32567 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 2.8 Cc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
1246434 32571 14 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 1 5 4.7 O=C(Nc1nnc(C2CCCCC2)s1)c1ccc(Br)s1 nan
CHEMBL1412704 32571 14 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 1 5 4.7 O=C(Nc1nnc(C2CCCCC2)s1)c1ccc(Br)s1 nan
1952877 32591 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 2 5 2.0 Cc1cc(C)c2oc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)cc(=O)c2c1 nan
CHEMBL1412873 32591 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 2 5 2.0 Cc1cc(C)c2oc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)cc(=O)c2c1 nan
16017227 32616 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 0 6 2.2 Cc1nn(CC(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)c(=O)c2cccn12 nan
CHEMBL1413003 32616 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 0 6 2.2 Cc1nn(CC(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)c(=O)c2cccn12 nan
15996885 32624 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 1 8 3.7 COc1cccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)c1 nan
CHEMBL1413061 32624 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 1 8 3.7 COc1cccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)c1 nan
2314879 32673 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 6 3.3 CCCCn1c2nc3ccccc3nc2c2c(=N)oc(C)nc21 nan
CHEMBL1413521 32673 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 6 3.3 CCCCn1c2nc3ccccc3nc2c2c(=N)oc(C)nc21 nan
694926 32688 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 1 5 3.3 Cc1cccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c1 nan
CHEMBL1413648 32688 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 1 5 3.3 Cc1cccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c1 nan
16025383 32798 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 6 4.4 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(F)cc1)S2(=O)=O)NCCc1ccccc1 nan
CHEMBL1414539 32798 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 6 4.4 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(F)cc1)S2(=O)=O)NCCc1ccccc1 nan
16010143 32863 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 3 5.6 Cc1ccc(Cn2c(C(=O)NCc3ccccc3Cl)cc3sccc32)cc1 nan
CHEMBL1415124 32863 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 3 5.6 Cc1ccc(Cn2c(C(=O)NCc3ccccc3Cl)cc3sccc32)cc1 nan
663372 32865 14 None -14 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 0 4 4.2 Cc1ccc(C2CC(=O)c3cnc(N4CC(C)CC(C)C4)nc3C2)cc1 nan
CHEMBL1415139 32865 14 None -14 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 0 4 4.2 Cc1ccc(C2CC(=O)c3cnc(N4CC(C)CC(C)C4)nc3C2)cc1 nan
16029519 32876 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 5 0 6 2.9 CN(C)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3cccc(Cl)c3)CC1)CCS2 nan
CHEMBL1415234 32876 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 5 0 6 2.9 CN(C)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3cccc(Cl)c3)CC1)CCS2 nan
1088534 32910 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 6 1 4 3.9 CCOc1ccc(NC(=O)Cn2cc(C(C)=O)c3ccccc32)cc1 nan
CHEMBL1415529 32910 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 6 1 4 3.9 CCOc1ccc(NC(=O)Cn2cc(C(C)=O)c3ccccc32)cc1 nan
2701522 32933 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 6 1 6 2.8 CCSc1nnc(NC(=O)Cc2ccccc2OC)s1 nan
CHEMBL1415759 32933 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 6 1 6 2.8 CCSc1nnc(NC(=O)Cc2ccccc2OC)s1 nan
20880977 33037 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 9 1 8 2.5 O=C(CCc1nnc2n(Cc3ccc(Cl)cc3)c(=O)c3ccccc3n12)NCCCN1CCOCC1 nan
CHEMBL1416665 33037 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 9 1 8 2.5 O=C(CCc1nnc2n(Cc3ccc(Cl)cc3)c(=O)c3ccccc3n12)NCCCN1CCOCC1 nan
16025415 33054 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 1 6 5.5 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2ccccc2C)S3(=O)=O)c1 nan
CHEMBL1416823 33054 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 1 6 5.5 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2ccccc2C)S3(=O)=O)c1 nan
24792644 33190 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 4 3.8 CN(C)c1ccc(-c2ccc3c(=O)c4ccccc4n(C)c3c2)cn1 nan
CHEMBL1417964 33190 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 4 3.8 CN(C)c1ccc(-c2ccc3c(=O)c4ccccc4n(C)c3c2)cn1 nan
16030529 33205 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 7 0 4 5.8 CCN(C(=O)CSc1nc2ccccc2nc1Cc1ccc(F)cc1)c1cccc(C)c1 nan
CHEMBL1418101 33205 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 7 0 4 5.8 CCN(C(=O)CSc1nc2ccccc2nc1Cc1ccc(F)cc1)c1cccc(C)c1 nan
1936615 33268 11 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 7 4.5 CC1(C)Cc2nc3sc4c(SCC(=O)NCc5ccccc5)ncnc4c3cc2CO1 nan
CHEMBL1418632 33268 11 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 7 4.5 CC1(C)Cc2nc3sc4c(SCC(=O)NCc5ccccc5)ncnc4c3cc2CO1 nan
3574260 33341 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccccc1Cl nan
CHEMBL1419267 33341 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccccc1Cl nan
5069803 33809 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 4 2.2 CC(C)C(=O)N1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1 nan
CHEMBL1423181 33809 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 4 2.2 CC(C)C(=O)N1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1 nan
4298772 33869 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 3 1 4 2.8 Cc1ccc(NC(=O)c2ccc(-n3cccn3)nc2)cc1 nan
CHEMBL1423637 33869 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 3 1 4 2.8 Cc1ccc(NC(=O)c2ccc(-n3cccn3)nc2)cc1 nan
135521903 33932 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 2 7 4.7 Cc1ccc(-n2c(SCC(=O)NCCC3=CCCCC3)nc3nnc(C)c-3c2N)cc1Cl nan
CHEMBL1424164 33932 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 2 7 4.7 Cc1ccc(-n2c(SCC(=O)NCCC3=CCCCC3)nc3nnc(C)c-3c2N)cc1Cl nan
5009230 34210 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 1 3 4.6 O=c1c2ccc(Cl)cc2[nH]c(=S)n1CCC1=CCCCC1 nan
CHEMBL1426475 34210 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 1 3 4.6 O=c1c2ccc(Cl)cc2[nH]c(=S)n1CCC1=CCCCC1 nan
1004501 34227 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 8 1 6 5.8 COc1ccc(-c2cc(-c3cccs3)c(C#N)c(SCC(=O)NCc3ccccc3)n2)cc1 nan
CHEMBL1426581 34227 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 8 1 6 5.8 COc1ccc(-c2cc(-c3cccs3)c(C#N)c(SCC(=O)NCc3ccccc3)n2)cc1 nan
1398121 34250 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 4 5.1 Cc1nc(Nc2ccccc2)c2oc3ccc(Cl)cc3c2n1 nan
CHEMBL1426816 34250 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 4 5.1 Cc1nc(Nc2ccccc2)c2oc3ccc(Cl)cc3c2n1 nan
2916457 34309 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 0 4 2.1 O=C1c2nc3ccccn3c2C(=O)N1Cc1ccccc1 nan
CHEMBL1427322 34309 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 0 4 2.1 O=C1c2nc3ccccn3c2C(=O)N1Cc1ccccc1 nan
2785858 34549 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 0 0 5 0.8 Cn1c(=O)c2cc3ccccc3nc2n(C)c1=O nan
CHEMBL1429441 34549 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 0 0 5 0.8 Cn1c(=O)c2cc3ccccc3nc2n(C)c1=O nan
1474449 34798 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 5 3.8 Nc1c(-c2cccs2)cnc2c(-c3ccc(F)cc3)cnn12 nan
CHEMBL1431364 34798 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 5 3.8 Nc1c(-c2cccs2)cnc2c(-c3ccc(F)cc3)cnn12 nan
22548378 34803 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 6 2.0 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3cc4c(cc3C)NC(=O)CO4)CC2)cc1 nan
CHEMBL1431452 34803 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 6 2.0 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3cc4c(cc3C)NC(=O)CO4)CC2)cc1 nan
3239990 34859 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 3 0 7 3.1 CCOC(=O)N1CCN(C(=O)c2nn(-c3ccc(C)cc3)c(=O)c3c2c2ccccc2n3C)CC1 nan
CHEMBL1431956 34859 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 3 0 7 3.1 CCOC(=O)N1CCN(C(=O)c2nn(-c3ccc(C)cc3)c(=O)c3c2c2ccccc2n3C)CC1 nan
1480466 34878 24 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CC(C)Nc1nc(-c2cccnc2)nc(-c2ccc(Cl)cc2)c1C#N nan
CHEMBL1432166 34878 24 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CC(C)Nc1nc(-c2cccnc2)nc(-c2ccc(Cl)cc2)c1C#N nan
24792375 34899 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 2.5 COc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
CHEMBL1432321 34899 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 2.5 COc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
1049756 35030 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 5 4.3 COc1ccccc1NC(=O)c1c(NC(=O)c2ccco2)sc2c1CCC2 nan
CHEMBL1433354 35030 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 5 4.3 COc1ccccc1NC(=O)c1c(NC(=O)c2ccco2)sc2c1CCC2 nan
2227785 35043 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 7 5.3 COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc(OC)c(OC)c(OC)c1 nan
CHEMBL1433437 35043 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 7 5.3 COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc(OC)c(OC)c(OC)c1 nan
16027247 35055 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 4.9 COc1ccc2ncc3c(-c4ccc(C)c(C)c4)nn(CC(=O)NC4CCCC4)c3c2c1 nan
CHEMBL1433603 35055 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 4.9 COc1ccc2ncc3c(-c4ccc(C)c(C)c4)nn(CC(=O)NC4CCCC4)c3c2c1 nan
16024617 35076 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 7 1 6 4.8 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)c(Cl)c3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1433920 35076 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 7 1 6 4.8 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)c(Cl)c3)c3nc(C)ccc3c2=O)cc1 nan
16019055 35095 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.0 Cc1ccccc1CCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1434234 35095 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.0 Cc1ccccc1CCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
2135389 35098 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 7 1 6 4.0 COc1cccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc(OC)ccc32)c1 nan
CHEMBL1434264 35098 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 7 1 6 4.0 COc1cccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc(OC)ccc32)c1 nan
16026966 35104 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 9 3.1 O=C(COc1ccc(F)cc1)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
CHEMBL1434365 35104 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 9 3.1 O=C(COc1ccc(F)cc1)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
16021030 35115 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 3 5.9 CC(CNC(=O)Cn1c(-c2cccs2)cc2cc(Cl)ccc21)c1ccccc1 nan
CHEMBL1434633 35115 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 3 5.9 CC(CNC(=O)Cn1c(-c2cccs2)cc2cc(Cl)ccc21)c1ccccc1 nan
2134800 35149 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 9 1 7 4.1 COCCCn1c(SCC(=O)NCc2ccccc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1435016 35149 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 9 1 7 4.1 COCCCn1c(SCC(=O)NCc2ccccc2)nc2c(sc3ccccc32)c1=O nan
16022354 35176 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 1 6 4.9 Cc1ccc(Cn2c(SCC(=O)NCc3ccc(Cl)cc3)nc3ccsc3c2=O)cc1 nan
CHEMBL1435272 35176 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 1 6 4.9 Cc1ccc(Cn2c(SCC(=O)NCc3ccc(Cl)cc3)nc3ccsc3c2=O)cc1 nan
16022956 35216 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.7 Cc1nnc(N2CCC(C(=O)NCCc3ccccc3)CC2)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
CHEMBL1435842 35216 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.7 Cc1nnc(N2CCC(C(=O)NCCc3ccccc3)CC2)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
16015098 35217 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 4.5 Cc1nc(SCC(=O)Nc2ccccc2C)cc(-c2ccccc2)n1 nan
CHEMBL1435853 35217 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 4.5 Cc1nc(SCC(=O)Nc2ccccc2C)cc(-c2ccccc2)n1 nan
16024515 35221 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 4.5 COc1ccc(Cl)cc1NC(=O)Cn1cc(C(=O)c2ccc(C)cc2)c(=O)c2ccc(C)nc21 nan
CHEMBL1435881 35221 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 4.5 COc1ccc(Cl)cc1NC(=O)Cn1cc(C(=O)c2ccc(C)cc2)c(=O)c2ccc(C)nc21 nan
16025955 35230 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 8 1.6 O=C(NCc1ccccc1Cl)c1cnc2sc(N3CCOCC3)nn2c1=O nan
CHEMBL1436007 35230 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 8 1.6 O=C(NCc1ccccc1Cl)c1cnc2sc(N3CCOCC3)nn2c1=O nan
15988055 35252 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 2 1 8 3.4 Cc1cccc(C)c1Nc1nn2c(=O)c3cc4c(cc3nc2s1)OCO4 nan
CHEMBL1436214 35252 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 2 1 8 3.4 Cc1cccc(C)c1Nc1nn2c(=O)c3cc4c(cc3nc2s1)OCO4 nan
1166237 35263 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 7 5.4 CCOc1ccc(NC(=O)CCSc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2)cc1 nan
CHEMBL1436413 35263 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 7 5.4 CCOc1ccc(NC(=O)CCSc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2)cc1 nan
4076476 35281 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.1 COc1cccc(C(=O)Nc2c(C(=O)c3ccc(F)cc3)oc3ccccc23)c1 nan
CHEMBL1436707 35281 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.1 COc1cccc(C(=O)Nc2c(C(=O)c3ccc(F)cc3)oc3ccccc23)c1 nan
16012965 35288 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 3 5.3 CCCCN(Cc1cc2cc(C)ccc2nc1O)C(=O)c1cccc(Cl)c1 nan
CHEMBL1436801 35288 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 3 5.3 CCCCN(Cc1cc2cc(C)ccc2nc1O)C(=O)c1cccc(Cl)c1 nan
16031323 35293 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 8 1 8 3.7 COc1cc(-c2cc3n(C)c(C)c(CCC(=O)Nc4ccc(F)cc4)c(=O)n3n2)cc(OC)c1OC nan
CHEMBL1436894 35293 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 8 1 8 3.7 COc1cc(-c2cc3n(C)c(C)c(CCC(=O)Nc4ccc(F)cc4)c(=O)n3n2)cc(OC)c1OC nan
3533132 35372 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 3.3 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)c1cncc(Br)c1 nan
CHEMBL1437784 35372 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 3.3 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)c1cncc(Br)c1 nan
4650106 35414 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 2 5 4.2 O=C(NCc1cccnc1)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 nan
CHEMBL1438098 35414 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 2 5 4.2 O=C(NCc1cccnc1)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 nan
959085 35500 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 1 4 3.5 CC(=O)c1sc(NC(=O)c2ccc(C)c(C)c2)nc1C nan
CHEMBL1438925 35500 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 1 4 3.5 CC(=O)c1sc(NC(=O)c2ccc(C)c(C)c2)nc1C nan
16026319 35521 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 4.5 CCc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4ccc(C)c(F)c4)c32)cc1 nan
CHEMBL1439096 35521 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 4.5 CCc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4ccc(C)c(F)c4)c32)cc1 nan
16015553 35523 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 6 2 6 5.2 Cc1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccco4)cc3s2)cc1 nan
CHEMBL1439122 35523 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 6 2 6 5.2 Cc1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccco4)cc3s2)cc1 nan
15988982 35644 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 524 8 2 7 3.8 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(CCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
CHEMBL1440158 35644 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 524 8 2 7 3.8 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(CCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
2137007 35884 9 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 8 2.8 COCCNc1nc2c(S(=O)(=O)c3cc(C)ccc3C)nnn2c2ccccc12 nan
CHEMBL1442335 35884 9 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 8 2.8 COCCNc1nc2c(S(=O)(=O)c3cc(C)ccc3C)nnn2c2ccccc12 nan
3156591 35902 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 7 3.0 CCCNS(=O)(=O)c1cc(-c2nnc3c4ccccc4c(C)nn23)ccc1OC nan
CHEMBL1442508 35902 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 7 3.0 CCCNS(=O)(=O)c1cc(-c2nnc3c4ccccc4c(C)nn23)ccc1OC nan
16009539 35942 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccccc4F)cc3)cc(=O)n12 nan
CHEMBL1442799 35942 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccccc4F)cc3)cc(=O)n12 nan
1119348 35960 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 0 6 4.2 COc1cccc2cc(-c3nnc(-c4ccc(Cl)cc4)o3)c(=O)oc12 nan
CHEMBL1443005 35960 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 0 6 4.2 COc1cccc2cc(-c3nnc(-c4ccc(Cl)cc4)o3)c(=O)oc12 nan
3456574 36140 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 2 5 1.8 COCCn1c(=S)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O nan
CHEMBL1444789 36140 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 2 5 1.8 COCCn1c(=S)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O nan
15987577 36156 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.3 Cc1cc(Cl)ccc1OCC(=O)Nc1c(Cl)ccc2nsnc12 nan
CHEMBL1444928 36156 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.3 Cc1cc(Cl)ccc1OCC(=O)Nc1c(Cl)ccc2nsnc12 nan
1529015 36158 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 5.3 CCOC(=O)c1c(-c2ccc(C)s2)csc1NC(=O)c1cccs1 nan
CHEMBL1444931 36158 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 5.3 CCOC(=O)c1c(-c2ccc(C)s2)csc1NC(=O)c1cccs1 nan
3238506 36191 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 1 7 3.0 CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3nc4ccccc4s3)cc2)CC1 nan
CHEMBL1445199 36191 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 1 7 3.0 CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3nc4ccccc4s3)cc2)CC1 nan
629629 36208 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 3 5.4 CC(=O)Nc1ccc(-c2cc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 nan
CHEMBL1445350 36208 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 3 5.4 CC(=O)Nc1ccc(-c2cc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 nan
16008367 36235 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 1 6 4.6 COc1cc(OC)c(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)cc1Cl nan
CHEMBL1445604 36235 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 1 6 4.6 COc1cc(OC)c(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)cc1Cl nan
16031877 36262 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 4.0 CCOC(=O)C1CCCN(Cc2cn3c(-c4ccc(Br)cc4)nnc3s2)C1 nan
CHEMBL1445888 36262 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 4.0 CCOC(=O)C1CCCN(Cc2cn3c(-c4ccc(Br)cc4)nnc3s2)C1 nan
3116123 36282 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 7 2.1 COc1ccccc1NC(=O)CSc1nc(N)c(C#N)cc1C#N nan
CHEMBL1446094 36282 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 7 2.1 COc1ccccc1NC(=O)CSc1nc(N)c(C#N)cc1C#N nan
3462774 36318 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 8 2 5 3.6 CCOCCCn1c(=S)[nH]c2cc(C(=O)NCc3ccc(F)cc3)ccc2c1=O nan
CHEMBL1446438 36318 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 8 2 5 3.6 CCOCCCn1c(=S)[nH]c2cc(C(=O)NCc3ccc(F)cc3)ccc2c1=O nan
1478332 36548 23 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 0 5 3.1 CCOC(=O)c1cc2c(=O)c3cc(C)ccc3oc2nc1C nan
CHEMBL1448380 36548 23 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 0 5 3.1 CCOC(=O)c1cc2c(=O)c3cc(C)ccc3oc2nc1C nan
15990626 36575 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 4 6.1 CCOc1ccc2ncc3c(-c4ccc(C)cc4)nn(-c4cccc(F)c4)c3c2c1 nan
CHEMBL1448570 36575 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 4 6.1 CCOc1ccc2ncc3c(-c4ccc(C)cc4)nn(-c4cccc(F)c4)c3c2c1 nan
16007612 36611 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 1 5 3.8 Cc1ccc(CCNC(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)cc1 nan
CHEMBL1448823 36611 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 1 5 3.8 Cc1ccc(CCNC(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)cc1 nan
2201274 36653 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 6 3.5 COc1cccc(-c2nnc(NC(=O)Cc3cccs3)s2)c1 nan
CHEMBL1449110 36653 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 6 3.5 COc1cccc(-c2nnc(NC(=O)Cc3cccs3)s2)c1 nan
16017301 36827 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 7 3.2 CC(C)CN(c1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2ccco2)s1 nan
CHEMBL1450497 36827 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 7 3.2 CC(C)CN(c1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2ccco2)s1 nan
3646626 36844 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 9 1 7 5.3 CC(C)OCCCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1450646 36844 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 9 1 7 5.3 CC(C)OCCCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
1389502 36894 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 1 3 4.0 O=C(Nc1cc(Cl)cc(Cl)c1)c1coc(=O)c(Br)c1 nan
CHEMBL1451156 36894 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 1 3 4.0 O=C(Nc1cc(Cl)cc(Cl)c1)c1coc(=O)c(Br)c1 nan
653554 36952 11 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 7 4.1 Cc1sc2nc(SCC(=O)NCc3ccco3)n(-c3ccccc3)c(=O)c2c1C nan
CHEMBL1451583 36952 11 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 7 4.1 Cc1sc2nc(SCC(=O)NCc3ccco3)n(-c3ccccc3)c(=O)c2c1C nan
135476823 36956 1 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 7 2.7 Cc1cccc(-n2c(SCC(=O)N3CCCC3)nc3nnc(C)c-3c2N)c1 nan
CHEMBL1451599 36956 1 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 7 2.7 Cc1cccc(-n2c(SCC(=O)N3CCCC3)nc3nnc(C)c-3c2N)c1 nan
2029273 37043 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 6 5.2 COc1cccc(-c2ccc(-c3noc(-c4ccccc4Br)n3)c(OC)n2)c1 nan
CHEMBL1452203 37043 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 6 5.2 COc1cccc(-c2ccc(-c3noc(-c4ccccc4Br)n3)c(OC)n2)c1 nan
5058847 37054 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 6 3.0 COc1cc(NC(=O)Cn2c(C)cc3ccccc3c2=O)cc(OC)c1OC nan
CHEMBL1452293 37054 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 6 3.0 COc1cc(NC(=O)Cn2c(C)cc3ccccc3c2=O)cc(OC)c1OC nan
16027444 37084 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
CHEMBL1452550 37084 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
4256434 37247 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 5.1 Cc1ccc(-c2nc(NC(=O)CSc3cc(C)c4ccccc4n3)ns2)cc1 nan
CHEMBL1453902 37247 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 5.1 Cc1ccc(-c2nc(NC(=O)CSc3cc(C)c4ccccc4n3)ns2)cc1 nan
16008459 37253 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 0 4 4.8 CCOc1ccc2c(c1)c(=O)c(C(=O)c1ccccc1)cn2Cc1ccccc1F nan
CHEMBL1453936 37253 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 0 4 4.8 CCOc1ccc2c(c1)c(=O)c(C(=O)c1ccccc1)cn2Cc1ccccc1F nan
991456 37279 3 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 4 4.1 COc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)NCc2ccco2)cc1 nan
CHEMBL1454096 37279 3 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 4 4.1 COc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)NCc2ccco2)cc1 nan
808336 37347 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 1 0 6 1.8 Cc1ccc(-c2nn3c(=O)c(C)nnc3s2)cc1 nan
CHEMBL1454681 37347 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 1 0 6 1.8 Cc1ccc(-c2nn3c(=O)c(C)nnc3s2)cc1 nan
16017701 37350 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 7 3.9 CCC(Sc1nc2nccnc2c(=O)n1Cc1ccc(C)cc1)C(=O)NC1CCCCC1 nan
CHEMBL1454690 37350 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 7 3.9 CCC(Sc1nc2nccnc2c(=O)n1Cc1ccc(C)cc1)C(=O)NC1CCCCC1 nan
15988663 37370 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 1 5 3.9 COc1ccc(OC)c(-c2cc(C(=O)NCc3ccc(Cl)cc3)no2)c1 nan
CHEMBL1454826 37370 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 1 5 3.9 COc1ccc(OC)c(-c2cc(C(=O)NCc3ccc(Cl)cc3)no2)c1 nan
599450 37467 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 1 3 3.6 O=C(Nc1ccc2c(c1)C(=O)OC2)c1ccc(C(F)(F)F)cc1 nan
CHEMBL1455771 37467 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 1 3 3.6 O=C(Nc1ccc2c(c1)C(=O)OC2)c1ccc(C(F)(F)F)cc1 nan
3981165 37499 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 5 2.5 CCOc1ncccc1C(=O)Nc1ccc(S(=O)(=O)N2CCCC2)cc1 nan
CHEMBL1456046 37499 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 5 2.5 CCOc1ncccc1C(=O)Nc1ccc(S(=O)(=O)N2CCCC2)cc1 nan
15989547 37514 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 8 1 5 3.6 O=C(CCn1c(=O)c2ccccc2n(Cc2cccc(Cl)c2)c1=O)NCCc1ccccc1 nan
CHEMBL1456174 37514 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 8 1 5 3.6 O=C(CCn1c(=O)c2ccccc2n(Cc2cccc(Cl)c2)c1=O)NCCc1ccccc1 nan
16027694 37549 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1ccccc1OCC(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1456495 37549 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1ccccc1OCC(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2ccsc2n1 nan
3242698 37579 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 2 7 4.2 Cc1ccccc1NC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
CHEMBL1456820 37579 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 2 7 4.2 Cc1ccccc1NC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
16024703 37632 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NC3CCCCC3)c2n1 nan
CHEMBL1457278 37632 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NC3CCCCC3)c2n1 nan
7066852 37642 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 2 3 5.8 Cc1ccc2nc(-c3c[nH]c4ccccc34)c(Nc3ccccc3C)n2c1 nan
CHEMBL1457410 37642 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 2 3 5.8 Cc1ccc2nc(-c3c[nH]c4ccccc34)c(Nc3ccccc3C)n2c1 nan
16030759 37658 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 0 6 4.4 O=C(c1ccc2c(c1)OCCO2)N(Cc1cccnc1)c1nc2ccc(F)cc2s1 nan
CHEMBL1457518 37658 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 0 6 4.4 O=C(c1ccc2c(c1)OCCO2)N(Cc1cccnc1)c1nc2ccc(F)cc2s1 nan
3347951 37664 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.5 CNC(=O)C(Sc1nc(C)nc2c1oc1ccccc12)C(C)=O nan
CHEMBL1457585 37664 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.5 CNC(=O)C(Sc1nc(C)nc2c1oc1ccccc12)C(C)=O nan
654954 37781 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 3.4 Cc1ccc2nc(SCC(=O)NCc3ccco3)c(C#N)cc2c1 nan
CHEMBL1458514 37781 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 3.4 Cc1ccc2nc(SCC(=O)NCc3ccco3)c(C#N)cc2c1 nan
861942 37838 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 0 6 3.7 COc1ccc(OC)c(-c2csc(N(C)C(=O)c3ccco3)n2)c1 nan
CHEMBL1458992 37838 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 0 6 3.7 COc1ccc(OC)c(-c2csc(N(C)C(=O)c3ccco3)n2)c1 nan
2570053 38119 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 0 7 1.8 Cc1ccnc2nc(C(=O)OCCOc3ccc(F)cc3)nn12 nan
CHEMBL1461384 38119 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 0 7 1.8 Cc1ccnc2nc(C(=O)OCCOc3ccc(F)cc3)nn12 nan
2109478 38145 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 4 1 5 3.9 Cc1cc(NC(=O)COc2ccc3oc4ccccc4c3c2)no1 nan
CHEMBL1461645 38145 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 4 1 5 3.9 Cc1cc(NC(=O)COc2ccc3oc4ccccc4c3c2)no1 nan
3243431 38153 7 None -11 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 2 4 5.6 CCOc1ccc(C(=O)Nc2ccc(NC(=O)c3ccco3)c(Cl)c2)cc1Br nan
CHEMBL1461732 38153 7 None -11 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 2 4 5.6 CCOc1ccc(C(=O)Nc2ccc(NC(=O)c3ccco3)c(Cl)c2)cc1Br nan
24789924 38244 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 1 8 3.7 COc1ccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)cc1 nan
CHEMBL1462423 38244 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 1 8 3.7 COc1ccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)cc1 nan
651585 38272 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 7 2.1 COC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 nan
CHEMBL1462713 38272 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 7 2.1 COC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 nan
2134888 38277 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 9 1 9 2.4 COc1ccc(C=O)cc1Cn1c(=O)n(CCC(=O)NCc2ccco2)c(=O)c2sccc21 nan
CHEMBL1462748 38277 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 9 1 9 2.4 COc1ccc(C=O)cc1Cn1c(=O)n(CCC(=O)NCc2ccco2)c(=O)c2sccc21 nan
658551 38573 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 7 2.0 CCCOC(=O)CSc1nc(N)c(C#N)c(CC)c1C#N nan
CHEMBL1465062 38573 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 7 2.0 CCCOC(=O)CSc1nc(N)c(C#N)c(CC)c1C#N nan
2571531 38598 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 0 10 3.3 CCCCn1c(SCc2cc(=O)n3ccsc3n2)nc2cc(C(=O)OC)ccc2c1=O nan
CHEMBL1465204 38598 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 0 10 3.3 CCCCn1c(SCc2cc(=O)n3ccsc3n2)nc2cc(C(=O)OC)ccc2c1=O nan
2207742 38600 8 None -11 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 6 3.8 CCc1c(C)sc(N=C(S)Nc2nc(C)cc(C)n2)c1C(=O)OC nan
CHEMBL1465216 38600 8 None -11 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 6 3.8 CCc1c(C)sc(N=C(S)Nc2nc(C)cc(C)n2)c1C(=O)OC nan
1299194 38782 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 8 3.9 CCOC(=O)c1ccc(NC(=O)CSc2nnc(-c3cccs3)n2CC)cc1 nan
CHEMBL1466656 38782 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 8 3.9 CCOC(=O)c1ccc(NC(=O)CSc2nnc(-c3cccs3)n2CC)cc1 nan
7502637 38836 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 3.3 COc1ccc(-c2ccc(SCC(=O)Nc3nccs3)nn2)cc1OC nan
CHEMBL1467089 38836 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 3.3 COc1ccc(-c2ccc(SCC(=O)Nc3nccs3)nn2)cc1OC nan
1086372 38852 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 1 5 4.7 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCCc3cccc(Cl)c3)n2)c1 nan
CHEMBL1467241 38852 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 1 5 4.7 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCCc3cccc(Cl)c3)n2)c1 nan
865458 38863 6 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 2 0 4 2.8 COc1ccc2nc(SC)c(C#N)cc2c1 nan
CHEMBL1467309 38863 6 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 2 0 4 2.8 COc1ccc2nc(SC)c(C#N)cc2c1 nan
20886167 39158 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.6 COc1cccc(CNC(=O)Cn2c(=O)c3cccn3c3ccccc32)c1 nan
CHEMBL1469817 39158 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.6 COc1cccc(CNC(=O)Cn2c(=O)c3cccn3c3ccccc32)c1 nan
2045894 39168 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 0 5 4.9 Cc1ccc(-c2nc(=S)c3c(n2Cc2cccnc2)CC(C)(C)OC3)cc1 nan
CHEMBL1469903 39168 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 0 5 4.9 Cc1ccc(-c2nc(=S)c3c(n2Cc2cccnc2)CC(C)(C)OC3)cc1 nan
1035368 39289 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 4.2 COc1ccc2nc(NC(=O)CSc3nc4ccccc4o3)sc2c1 nan
CHEMBL1470920 39289 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 4.2 COc1ccc2nc(NC(=O)CSc3nc4ccccc4o3)sc2c1 nan
16009198 39467 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCO4)cc1 nan
CHEMBL1472528 39467 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCO4)cc1 nan
15988292 39479 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 586 8 3 6 6.3 COCCCNC(=O)c1sc2nc(C)c(C(=O)Nc3ccc(Cl)cc3)c(-c3ccc(Br)cc3)c2c1N nan
CHEMBL1472621 39479 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 586 8 3 6 6.3 COCCCNC(=O)c1sc2nc(C)c(C(=O)Nc3ccc(Cl)cc3)c(-c3ccc(Br)cc3)c2c1N nan
16027199 39500 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 6 3.7 CC(C)NC(=O)C1CCC(Cn2c(=O)c3sccc3n(Cc3ccc(F)cc3)c2=O)CC1 nan
CHEMBL1472919 39500 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 6 3.7 CC(C)NC(=O)C1CCC(Cn2c(=O)c3sccc3n(Cc3ccc(F)cc3)c2=O)CC1 nan
15988974 39504 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 12 2 7 4.6 CCc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccc(C)cc2)c(=O)c2sccc21 nan
CHEMBL1472973 39504 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 12 2 7 4.6 CCc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccc(C)cc2)c(=O)c2sccc21 nan
9505887 39518 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 0 6 2.3 N#Cc1ccc(OC(=O)C2CCN(C3=NS(=O)(=O)c4ccccc43)CC2)cc1 nan
CHEMBL1473154 39518 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 0 6 2.3 N#Cc1ccc(OC(=O)C2CCN(C3=NS(=O)(=O)c4ccccc43)CC2)cc1 nan
16021070 39522 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 3.7 COc1ccc(OC)c(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
CHEMBL1473236 39522 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 3.7 COc1ccc(OC)c(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
7786274 39530 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 2 5 3.0 O=C(COC(=O)c1cc(Br)ccc1O)Nc1cccnc1Cl nan
CHEMBL1473370 39530 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 2 5 3.0 O=C(COC(=O)c1cc(Br)ccc1O)Nc1cccnc1Cl nan
16017273 39545 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 5 1.7 Cc1nn(CC(=O)Nc2cc(F)ccc2F)c(=O)c2cccn12 nan
CHEMBL1473495 39545 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 5 1.7 Cc1nn(CC(=O)Nc2cc(F)ccc2F)c(=O)c2cccn12 nan
15990603 39581 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 5 6.2 CCOC(=O)c1ccc2ncc3c(-c4ccccc4)nn(-c4ccc(F)c(Cl)c4)c3c2c1 nan
CHEMBL1474033 39581 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 5 6.2 CCOC(=O)c1ccc2ncc3c(-c4ccccc4)nn(-c4ccc(F)c(Cl)c4)c3c2c1 nan
16015614 39601 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 5 5.1 CC(C)C(=O)Nc1ccc2nc(SCCOc3ccccc3)sc2c1 nan
CHEMBL1474414 39601 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 5 5.1 CC(C)C(=O)Nc1ccc2nc(SCCOc3ccccc3)sc2c1 nan
16012115 39609 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 3.7 COc1cccc(CNC(=O)Cn2ncc3c4ccccc4n(Cc4ccccc4)c3c2=O)c1 nan
CHEMBL1474469 39609 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 3.7 COc1cccc(CNC(=O)Cn2ncc3c4ccccc4n(Cc4ccccc4)c3c2=O)c1 nan
15987618 39628 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 3 0 4 5.7 CCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c1cccc(C(F)(F)F)c1 nan
CHEMBL1474699 39628 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 3 0 4 5.7 CCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c1cccc(C(F)(F)F)c1 nan
16016392 39629 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 1 4 4.9 CC(C)NC(=O)N1[C@H](c2cccs2)[C@@H](C)C(=O)[C@@H](C)[C@@H]1c1cccs1 nan
CHEMBL1474706 39629 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 1 4 4.9 CC(C)NC(=O)N1[C@H](c2cccs2)[C@@H](C)C(=O)[C@@H](C)[C@@H]1c1cccs1 nan
15989047 39661 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 8 1 9 3.0 N#Cc1ccccc1Cn1c(=O)n(CCCC(=O)NCc2ccc3c(c2)OCO3)c(=O)c2sccc21 nan
CHEMBL1475184 39661 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 8 1 9 3.0 N#Cc1ccccc1Cn1c(=O)n(CCCC(=O)NCc2ccc3c(c2)OCO3)c(=O)c2sccc21 nan
1300955 39687 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 4.1 COc1ccc(CNc2ncnc3c2cnn3-c2ccc(Cl)cc2)cc1 nan
CHEMBL1475511 39687 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 4.1 COc1ccc(CNc2ncnc3c2cnn3-c2ccc(Cl)cc2)cc1 nan
16021946 39719 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 4 0 6 4.8 Cc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1CC(=O)c1ccc(Cl)cc1)n2C nan
CHEMBL1475915 39719 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 4 0 6 4.8 Cc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1CC(=O)c1ccc(Cl)cc1)n2C nan
16009716 39755 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 6 4.1 O=C(Cn1c(=O)n(-c2ccccc2Cl)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
CHEMBL1476522 39755 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 6 4.1 O=C(Cn1c(=O)n(-c2ccccc2Cl)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
2387574 39845 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.0 CCS(=O)(=O)c1ccc2oc(Nc3cc(Cl)ccc3OC)nc2c1 nan
CHEMBL1477466 39845 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.0 CCS(=O)(=O)c1ccc2oc(Nc3cc(Cl)ccc3OC)nc2c1 nan
651813 39846 7 None -7 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 6 4.1 CCc1nc(SCC(=O)NCc2ccco2)c2c3c(sc2n1)CCCC3 nan
CHEMBL1477471 39846 7 None -7 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 6 4.1 CCc1nc(SCC(=O)NCc2ccco2)c2c3c(sc2n1)CCCC3 nan
135542325 39883 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 7 4.0 Cc1nnc2nc(SCC(=O)NC3CCCCC3)n(-c3ccc(Br)cc3)c(N)c1-2 nan
CHEMBL1477773 39883 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 7 4.0 Cc1nnc2nc(SCC(=O)NC3CCCCC3)n(-c3ccc(Br)cc3)c(N)c1-2 nan
4154279 39900 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 5 5.5 Cc1c(Cl)cccc1NC(=O)CSc1ncnc2c1sc1ccccc12 nan
CHEMBL1477945 39900 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 5 5.5 Cc1c(Cl)cccc1NC(=O)CSc1ncnc2c1sc1ccccc12 nan
647217 39948 1 None 1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 8 3.5 CCS(=O)(=O)Nc1ccc(-c2nnc(SCC(=O)c3cccc(OC)c3)o2)cc1 nan
CHEMBL1478450 39948 1 None 1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 8 3.5 CCS(=O)(=O)Nc1ccc(-c2nnc(SCC(=O)c3cccc(OC)c3)o2)cc1 nan
356316 40057 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 4 2.9 Cc1ccc(S(=O)(=O)c2cc3ccccc3oc2=O)cc1 nan
CHEMBL1479392 40057 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 4 2.9 Cc1ccc(S(=O)(=O)c2cc3ccccc3oc2=O)cc1 nan
16009796 40195 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 6 4.4 COc1ccc(-n2c(=O)c3sc4ccccc4c3n(Cc3ccccc3)c2=O)cc1 nan
CHEMBL1480505 40195 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 6 4.4 COc1ccc(-n2c(=O)c3sc4ccccc4c3n(Cc3ccccc3)c2=O)cc1 nan
16024583 40223 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 1 7 3.5 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)Nc3ccc4c(c3)OCCO4)c2n1 nan
CHEMBL1480766 40223 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 1 7 3.5 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)Nc3ccc4c(c3)OCCO4)c2n1 nan
3273049 40316 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 533 7 1 7 4.4 CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(C(C)C)C2 nan
CHEMBL1481475 40316 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 533 7 1 7 4.4 CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(C(C)C)C2 nan
3662250 40343 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 2.9 COc1ccc(-c2cc(C(=O)Nc3cc(C)on3)no2)cc1OC nan
CHEMBL1481783 40343 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 2.9 COc1ccc(-c2cc(C(=O)Nc3cc(C)on3)no2)cc1OC nan
5763301 40420 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 0 3 3.8 Cn1c(/C=C/c2ccc(Cl)cc2)nc2ccccc2c1=O nan
CHEMBL1482443 40420 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 0 3 3.8 Cn1c(/C=C/c2ccc(Cl)cc2)nc2ccccc2c1=O nan
16030274 40488 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 2 3 4.4 Cc1cccc2c(=O)cc(CSCC(=O)Nc3ccc(Cl)cc3)[nH]c12 nan
CHEMBL1483081 40488 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 2 3 4.4 Cc1cccc2c(=O)cc(CSCC(=O)Nc3ccc(Cl)cc3)[nH]c12 nan
135419126 40532 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 2 1 3 6.5 Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(c2cccc(Br)c2)C1 nan
CHEMBL1483478 40532 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 2 1 3 6.5 Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(c2cccc(Br)c2)C1 nan
16010346 40547 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 0 7 5.0 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N(C)Cc2ccccc2)c2cc(Cl)ccc23)cc1C nan
CHEMBL1483574 40547 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 0 7 5.0 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N(C)Cc2ccccc2)c2cc(Cl)ccc23)cc1C nan
1482113 40740 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 5 2 5 3.7 COCc1cc(O)nc2cc(NC(=O)c3cccc(OC)c3)c(C)cc12 nan
CHEMBL1485213 40740 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 5 2 5 3.7 COCc1cc(O)nc2cc(NC(=O)c3cccc(OC)c3)c(C)cc12 nan
848452 40776 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 4 2.9 COC(=O)c1ccc2ccn(CC(=O)NC3CCCCC3)c2c1 nan
CHEMBL1485568 40776 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 4 2.9 COC(=O)c1ccc2ccn(CC(=O)NC3CCCCC3)c2c1 nan
6491858 40897 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 7 3.4 COc1cccc(NC(=O)CSc2nc(O)c3c(C)csc3n2)c1 nan
CHEMBL1486601 40897 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 7 3.4 COc1cccc(NC(=O)CSc2nc(O)c3c(C)csc3n2)c1 nan
12005495 40932 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 2 4 4.0 Cc1cccc(C)c1NC(=O)C(NS(=O)(=O)c1cccs1)c1ccccc1 nan
CHEMBL1486971 40932 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 2 4 4.0 Cc1cccc(C)c1NC(=O)C(NS(=O)(=O)c1cccs1)c1ccccc1 nan
2007999 41003 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 6 3.4 CC(C)c1nc2sc3c(SCC(N)=O)ncnc3c2c2c1CCC2 nan
CHEMBL1487512 41003 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 6 3.4 CC(C)c1nc2sc3c(SCC(N)=O)ncnc3c2c2c1CCC2 nan
1604294 41030 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 4 5.9 Cc1ccc(OCCCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)cc1 nan
CHEMBL1487726 41030 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 4 5.9 Cc1ccc(OCCCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)cc1 nan
3847044 41196 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 8 4.1 COC(=O)CSc1nc2sc3c(c2c(=O)n1-c1ccc(C)cc1)CC(C(C)C)OC3 nan
CHEMBL1488882 41196 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 8 4.1 COC(=O)CSc1nc2sc3c(c2c(=O)n1-c1ccc(C)cc1)CC(C(C)C)OC3 nan
3531068 41265 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 5 1 8 4.5 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc3nc(-c4ccc(C)cc4)cc(C(F)(F)F)n3n2)c1 nan
CHEMBL1489426 41265 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 5 1 8 4.5 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc3nc(-c4ccc(C)cc4)cc(C(F)(F)F)n3n2)c1 nan
3149408 41351 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 6 8 -1.2 Cc1ccc(C2=NNC(C(O)C(O)C(O)C(O)CO)S2)cc1 nan
CHEMBL1490120 41351 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 6 8 -1.2 Cc1ccc(C2=NNC(C(O)C(O)C(O)C(O)CO)S2)cc1 nan
15996835 41419 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 6 3.9 COc1cc2nc(S)nc(NCCc3ccc(C)cc3)c2cc1OC nan
CHEMBL1490579 41419 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 6 3.9 COc1cc2nc(S)nc(NCCc3ccc(C)cc3)c2cc1OC nan
5216415 41457 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 0 5 5.2 COc1cccc2cc(-c3nc(-c4ccc(Cl)cc4)cs3)c(=O)oc12 nan
CHEMBL1490839 41457 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 0 5 5.2 COc1cccc2cc(-c3nc(-c4ccc(Cl)cc4)cs3)c(=O)oc12 nan
16022523 41516 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 7 2.3 Cn1cnc2c(=O)oc3ccc(S(=O)(=O)N4CCN(c5ccccc5F)CC4)cc3c21 nan
CHEMBL1491216 41516 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 7 2.3 Cn1cnc2c(=O)oc3ccc(S(=O)(=O)N4CCN(c5ccccc5F)CC4)cc3c21 nan
16034710 41744 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 5 3.9 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccccc3)c2n1 nan
CHEMBL1492881 41744 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 5 3.9 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccccc3)c2n1 nan
1319924 41773 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 9 0 6 4.8 CCCS(=O)(=O)c1c(S(=O)(=O)CCC)c2cc(CC)ccn2c1C(=O)c1ccc(Cl)cc1 nan
CHEMBL1493213 41773 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 9 0 6 4.8 CCCS(=O)(=O)c1c(S(=O)(=O)CCC)c2cc(CC)ccn2c1C(=O)c1ccc(Cl)cc1 nan
16423380 41789 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 7 2.9 COc1ccc(-c2cc3ccc(O)c(CN4CCN(C)CC4)c3oc2=O)cc1OC nan
7205024 41789 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 7 2.9 COc1ccc(-c2cc3ccc(O)c(CN4CCN(C)CC4)c3oc2=O)cc1OC nan
CHEMBL1493339 41789 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 7 2.9 COc1ccc(-c2cc3ccc(O)c(CN4CCN(C)CC4)c3oc2=O)cc1OC nan
6823777 41815 6 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 526 8 3 6 3.3 Cc1ccc(-n2c([S-])c(C(=O)Nc3ccc(OC(F)F)cc3)[n+]3ccc(C(=O)NCCO)cc23)cc1C nan
CHEMBL1493546 41815 6 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 526 8 3 6 3.3 Cc1ccc(-n2c([S-])c(C(=O)Nc3ccc(OC(F)F)cc3)[n+]3ccc(C(=O)NCCO)cc23)cc1C nan
1091748 41819 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 2 5 3.5 O=C(Nc1ccccc1C(=O)Nc1ccc2c(c1)OCO2)c1ccco1 nan
CHEMBL1493592 41819 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 2 5 3.5 O=C(Nc1ccccc1C(=O)Nc1ccc2c(c1)OCO2)c1ccco1 nan
4885142 42208 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 4 4.4 CC(=O)c1ccc(N2CCN(c3ccnc4cc(Cl)ccc34)CC2)cc1 nan
CHEMBL1497325 42208 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 4 4.4 CC(=O)c1ccc(N2CCN(c3ccnc4cc(Cl)ccc34)CC2)cc1 nan
665746 42263 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 0 5 3.5 O=C1c2oc3ccccc3c(=O)c2C(c2cccnc2)N1Cc1ccco1 nan
CHEMBL1497863 42263 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 0 5 3.5 O=C1c2oc3ccccc3c(=O)c2C(c2cccnc2)N1Cc1ccco1 nan
1478337 42292 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 2 1 4 5.2 Cc1ccc2oc3nc(C)c(C(=O)Nc4cccc(C(F)(F)F)c4)cc3c(=O)c2c1 nan
CHEMBL1498149 42292 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 2 1 4 5.2 Cc1ccc2oc3nc(C)c(C(=O)Nc4cccc(C(F)(F)F)c4)cc3c(=O)c2c1 nan
1877175 42381 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 1 6 2.9 CCOc1ccc(C(=O)Nc2nc(C)c(C(=O)OC)s2)cc1 nan
CHEMBL1498972 42381 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 1 6 2.9 CCOc1ccc(C(=O)Nc2nc(C)c(C(=O)OC)s2)cc1 nan
663555 42628 10 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.6 Cc1cccc(C(=O)OCc2cc3ccccc3nc2O)c1 nan
CHEMBL1501108 42628 10 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.6 Cc1cccc(C(=O)OCc2cc3ccccc3nc2O)c1 nan
1482342 42809 24 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 2 1 7 2.2 CSc1nc2ncc(-c3ccsc3)c(N)n2n1 nan
CHEMBL1502638 42809 24 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 2 1 7 2.2 CSc1nc2ncc(-c3ccsc3)c(N)n2n1 nan
6624089 43084 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 5 1 4 3.3 O=C(Cn1c(=O)c2cccn2c2ccccc21)NCCc1ccc(Cl)cc1 nan
CHEMBL1505154 43084 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 5 1 4 3.3 O=C(Cn1c(=O)c2cccn2c2ccccc21)NCCc1ccc(Cl)cc1 nan
1488509 43112 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 240 3 1 4 1.9 O=C(Nc1ccnc(-c2ccncc2)n1)C1CC1 nan
CHEMBL1505422 43112 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 240 3 1 4 1.9 O=C(Nc1ccnc(-c2ccncc2)n1)C1CC1 nan
8484069 43292 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 8 3.3 CC(=O)c1ccc(NC(=O)CSc2nnc(NC(=O)c3ccco3)s2)cc1 nan
CHEMBL1506911 43292 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 8 3.3 CC(=O)c1ccc(NC(=O)CSc2nnc(NC(=O)c3ccco3)s2)cc1 nan
2880344 43337 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 6 4.7 COc1ccc(CC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)cc1OC nan
CHEMBL1507312 43337 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 6 4.7 COc1ccc(CC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)cc1OC nan
1440345 43426 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 3 1 3 3.2 Cc1cc2cc3c(cc2nc1SCC(=O)O)CCC3 nan
CHEMBL1508003 43426 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 3 1 3 3.2 Cc1cc2cc3c(cc2nc1SCC(=O)O)CCC3 nan
4435004 43615 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 4 1 3 3.8 CCCn1c(NC(=O)c2ccc(F)cc2)nc2ccccc21 nan
CHEMBL1509719 43615 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 4 1 3 3.8 CCCn1c(NC(=O)c2ccc(F)cc2)nc2ccccc21 nan
2676980 43637 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 6 2.6 O=C(Cn1cnc2ccccc2c1=O)Nc1nc2ccccc2s1 nan
CHEMBL1509918 43637 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 6 2.6 O=C(Cn1cnc2ccccc2c1=O)Nc1nc2ccccc2s1 nan
2402709 43687 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 2 7 3.0 NS(=O)(=O)c1ccc(NC(=O)COC(=O)c2cn(-c3ccccc3)nc2-c2ccccc2)cc1 nan
CHEMBL1510422 43687 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 2 7 3.0 NS(=O)(=O)c1ccc(NC(=O)COC(=O)c2cn(-c3ccccc3)nc2-c2ccccc2)cc1 nan
16024491 43896 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 7 3.3 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccc4c(c3)OCCO4)c2n1 nan
CHEMBL1512438 43896 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 7 3.3 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccc4c(c3)OCCO4)c2n1 nan
7184798 43904 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 7 3.5 CC(C)Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCCCC3)nnc12 nan
CHEMBL1512523 43904 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 7 3.5 CC(C)Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCCCC3)nnc12 nan
16025847 43922 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.4 Cc1cccc(CNC(=O)c2cnc3sc(N4CCCCC4)nn3c2=O)c1 nan
CHEMBL1512717 43922 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.4 Cc1cccc(CNC(=O)c2cnc3sc(N4CCCCC4)nn3c2=O)c1 nan
16026525 43923 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 4.6 CCc1ccccc1NC(=O)C(C)n1c(=O)cc(C)c2c(C)nn(-c3ccccc3)c21 nan
CHEMBL1512723 43923 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 4.6 CCc1ccccc1NC(=O)C(C)n1c(=O)cc(C)c2c(C)nn(-c3ccccc3)c21 nan
16026338 43925 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 5 4.7 Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4cc(Cl)ccc4C)c32)cc1 nan
CHEMBL1512750 43925 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 5 4.7 Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4cc(Cl)ccc4C)c32)cc1 nan
7066893 43945 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 2 6 4.8 COc1cc(-c2nc3sccn3c2Nc2cccc(C)c2)ccc1O nan
CHEMBL1513064 43945 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 2 6 4.8 COc1cc(-c2nc3sccn3c2Nc2cccc(C)c2)ccc1O nan
16025357 43955 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 6 1 6 5.8 Cc1ccc(CN2c3ccccc3-c3nc(SCC(=O)Nc4c(C)cc(C)cc4C)ncc3S2(=O)=O)cc1 nan
CHEMBL1513190 43955 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 6 1 6 5.8 Cc1ccc(CN2c3ccccc3-c3nc(SCC(=O)Nc4c(C)cc(C)cc4C)ncc3S2(=O)=O)cc1 nan
16010879 43983 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.9 COc1cc2nc(NCCc3cccc(C)c3)n3nc(-c4ccccc4)nc3c2cc1OC nan
CHEMBL1513631 43983 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.9 COc1cc2nc(NCCc3cccc(C)c3)n3nc(-c4ccccc4)nc3c2cc1OC nan
2947326 44010 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 2 6 3.9 CCOC(=O)c1ccc(NC(=O)CSc2nc3c(C)c(Br)cnc3[nH]2)cc1 nan
CHEMBL1514184 44010 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 2 6 3.9 CCOC(=O)c1ccc(NC(=O)CSc2nc3c(C)c(Br)cnc3[nH]2)cc1 nan
15988389 44047 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 3 5.3 O=C(NCCc1ccccc1)c1cc(-c2ccccc2)nc2n[nH]c(-c3ccccc3)c12 nan
CHEMBL1514741 44047 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 3 5.3 O=C(NCCc1ccccc1)c1cc(-c2ccccc2)nc2n[nH]c(-c3ccccc3)c12 nan
16027439 44081 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 7 4.3 Cc1csc2nc(COC(=O)c3cccc(NC(=O)c4cccc(Cl)c4)c3)cc(=O)n12 nan
CHEMBL1515224 44081 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 7 4.3 Cc1csc2nc(COC(=O)c3cccc(NC(=O)c4cccc(Cl)c4)c3)cc(=O)n12 nan
3324743 44085 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 1 4 5.2 CCc1ccc(OCC(=O)Nc2c(C(=O)c3ccccc3)oc3ccccc23)cc1 nan
CHEMBL1515282 44085 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 1 4 5.2 CCc1ccc(OCC(=O)Nc2c(C(=O)c3ccccc3)oc3ccccc23)cc1 nan
1035668 44131 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 5 5.7 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1 nan
CHEMBL1515955 44131 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 5 5.7 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1 nan
16009680 44149 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 0 4 4.6 Cc1ccc(S(=O)(=O)c2cn(Cc3ccc(F)cc3)c3cc(F)c(F)cc3c2=O)cc1 nan
CHEMBL1516142 44149 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 0 4 4.6 Cc1ccc(S(=O)(=O)c2cn(Cc3ccc(F)cc3)c3cc(F)c(F)cc3c2=O)cc1 nan
1516716 44172 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 3 5 3.7 Nc1c(C(=O)Nc2ccc(C(=O)O)cc2)sc2nc3c(cc12)CCCC3 nan
CHEMBL1516550 44172 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 3 5 3.7 Nc1c(C(=O)Nc2ccc(C(=O)O)cc2)sc2nc3c(cc12)CCCC3 nan
15989644 44174 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 531 5 1 5 4.1 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)N3CCC(C)CC3)c3ccccc3c2=O)c(Br)c1 nan
CHEMBL1516553 44174 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 531 5 1 5 4.1 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)N3CCC(C)CC3)c3ccccc3c2=O)c(Br)c1 nan
16027696 44211 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1cccc(OCC(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
CHEMBL1516896 44211 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1cccc(OCC(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
16009847 44269 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 4 0 6 5.1 O=c1c2sc3ccccc3c2n(Cc2cccc(C(F)(F)F)c2)c(=O)n1Cc1ccco1 nan
CHEMBL1517455 44269 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 4 0 6 5.1 O=c1c2sc3ccccc3c2n(Cc2cccc(C(F)(F)F)c2)c(=O)n1Cc1ccco1 nan
16010572 44271 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 8 4.0 COc1ccc(OC)c(CCNc2nc3ccccc3c3nc(-c4cccnc4)nn23)c1 nan
CHEMBL1517540 44271 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 8 4.0 COc1ccc(OC)c(CCNc2nc3ccccc3c3nc(-c4cccnc4)nn23)c1 nan
1073734 44279 19 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 5 3.6 Cc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1C nan
CHEMBL1517640 44279 19 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 5 3.6 Cc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1C nan
15990463 44350 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 543 8 2 6 4.6 Cc1cccc(NC(=O)CSC2=Nc3ccccc3C3=NC(CCC(=O)NCc4ccc(F)cc4)C(=O)N23)c1 nan
CHEMBL1518319 44350 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 543 8 2 6 4.6 Cc1cccc(NC(=O)CSC2=Nc3ccccc3C3=NC(CCC(=O)NCc4ccc(F)cc4)C(=O)N23)c1 nan
890719 44402 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 4 2 4 0.9 CCN1C(=O)/C(=C\NCc2ccccc2)C(=O)NC1=S nan
CHEMBL1518771 44402 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 4 2 4 0.9 CCN1C(=O)/C(=C\NCc2ccccc2)C(=O)NC1=S nan
4457184 44423 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 2 2 7 2.2 N#Cc1c(N2CCCCC2)nc(N)c2c(N)nc3c(c12)CC(CCl)O3 nan
CHEMBL1518944 44423 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 2 2 7 2.2 N#Cc1c(N2CCCCC2)nc(N)c2c(N)nc3c(c12)CC(CCl)O3 nan
16013971 44453 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 0 7 3.7 Cc1nnc(N2CCN(c3ccc(Cl)cc3)CC2)c2c1nnn2Cc1ccc(F)cc1 nan
CHEMBL1519203 44453 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 0 7 3.7 Cc1nnc(N2CCN(c3ccc(Cl)cc3)CC2)c2c1nnn2Cc1ccc(F)cc1 nan
1557528 44473 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 8 0 5 5.1 Cc1ccc(OCCOCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)cc1 nan
CHEMBL1519353 44473 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 8 0 5 5.1 Cc1ccc(OCCOCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)cc1 nan
2158290 44507 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 9 0 9 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CCCOC)/c1=N/C(=O)C(C)(C)Oc1ccc(Cl)cc1 nan
CHEMBL1519687 44507 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 9 0 9 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CCCOC)/c1=N/C(=O)C(C)(C)Oc1ccc(Cl)cc1 nan
4379652 44648 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 10 1.1 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3cccs3)nc2n(C)c1=O nan
CHEMBL1520875 44648 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 10 1.1 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3cccs3)nc2n(C)c1=O nan
5925852 44694 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 1 10 3.2 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1521267 44694 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 1 10 3.2 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
16018871 44730 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 7 1 6 2.8 COc1ccc(CNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1521570 44730 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 7 1 6 2.8 COc1ccc(CNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)cc1 nan
17252948 44832 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 5 3.9 Cc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1C nan
CHEMBL1522534 44832 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 5 3.9 Cc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1C nan
16009486 44869 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 9 3.9 COc1cc(C(=O)Nc2ccccc2OCc2cc(=O)n3c(C)csc3n2)cc(OC)c1OC nan
CHEMBL1522858 44869 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 9 3.9 COc1cc(C(=O)Nc2ccccc2OCc2cc(=O)n3c(C)csc3n2)cc(OC)c1OC nan
932437 44899 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 4 4.9 Cc1ccc(-c2nnc3c4ccccc4c(-c4ccccc4)nn23)cc1 nan
CHEMBL1523117 44899 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 4 4.9 Cc1ccc(-c2nnc3c4ccccc4c(-c4ccccc4)nn23)cc1 nan
2084813 44947 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 2 2 3.5 CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(F)ccc2C)c1C nan
CHEMBL1523555 44947 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 2 2 3.5 CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(F)ccc2C)c1C nan
663733 44990 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 8 3.1 Cc1nc2c(sc3nc4c(cc32)COC(C)(C)C4)c(=O)n1CC(=O)NCc1ccco1 nan
CHEMBL1523984 44990 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 8 3.1 Cc1nc2c(sc3nc4c(cc32)COC(C)(C)C4)c(=O)n1CC(=O)NCc1ccco1 nan
16027443 45095 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 7 4.3 Cc1csc2nc(COC(=O)c3ccccc3NC(=O)c3ccccc3Cl)cc(=O)n12 nan
CHEMBL1525043 45095 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 7 4.3 Cc1csc2nc(COC(=O)c3ccccc3NC(=O)c3ccccc3Cl)cc(=O)n12 nan
1299413 45186 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 5 3.1 C=CCn1c(SCC(=O)NC2CCCCC2)nc2ccccc2c1=O nan
CHEMBL1525864 45186 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 5 3.1 C=CCn1c(SCC(=O)NC2CCCCC2)nc2ccccc2c1=O nan
4174172 45346 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 7 0 6 4.9 COc1cc2c(cc1OC)C(COc1ccc3c(C)cc(=O)oc3c1)N(C(=O)Cc1ccccc1)CC2 nan
CHEMBL1527205 45346 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 7 0 6 4.9 COc1cc2c(cc1OC)C(COc1ccc3c(C)cc(=O)oc3c1)N(C(=O)Cc1ccccc1)CC2 nan
757005 45625 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 8 2 5 2.7 CCCc1cc(C(=O)OC)c(NC(=O)CCCC(=O)O)s1 nan
CHEMBL1529664 45625 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 8 2 5 2.7 CCCc1cc(C(=O)OC)c(NC(=O)CCCC(=O)O)s1 nan
4067774 45729 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 7 1 4 6.0 CCCOc1ccc(C(=O)Nc2c(C(=O)c3ccc(C)cc3)oc3ccccc23)cc1 nan
CHEMBL1530590 45729 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 7 1 4 6.0 CCCOc1ccc(C(=O)Nc2c(C(=O)c3ccc(C)cc3)oc3ccccc23)cc1 nan
3420293 45868 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 4 1 7 2.9 Cc1ccc(NC(=O)c2sc3ncn(CC(=O)N4CCOCC4)c(=O)c3c2C)c(Br)c1 nan
CHEMBL1531811 45868 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 4 1 7 2.9 Cc1ccc(NC(=O)c2sc3ncn(CC(=O)N4CCOCC4)c(=O)c3c2C)c(Br)c1 nan
821799 45894 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 5 2.1 CSc1nc2ccc(Br)cn2c(=O)c1C#N nan
CHEMBL1532047 45894 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 5 2.1 CSc1nc2ccc(Br)cn2c(=O)c1C#N nan
1475615 45923 18 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 6 5.0 O=C(Nc1cc2c(=O)n(-c3ccc(Oc4ccccc4)cc3)ccc2oc1=O)c1ccccc1 nan
CHEMBL1532311 45923 18 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 6 5.0 O=C(Nc1cc2c(=O)n(-c3ccc(Oc4ccccc4)cc3)ccc2oc1=O)c1ccccc1 nan
15989915 45967 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 5 4.6 COc1ccc(C2CC(=O)c3c([nH]c(C(=O)OCc4ccccc4)c3C)C2)cc1OC nan
CHEMBL1532686 45967 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 5 4.6 COc1ccc(C2CC(=O)c3c([nH]c(C(=O)OCc4ccccc4)c3C)C2)cc1OC nan
656128 45996 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 5 0 6 2.8 CCOc1ccc2cc(C#N)c(SCC(=O)OC)nc2c1 nan
CHEMBL1532931 45996 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 5 0 6 2.8 CCOc1ccc2cc(C#N)c(SCC(=O)OC)nc2c1 nan
3137936 46125 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 5 3.4 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2C)c1C nan
CHEMBL1534032 46125 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 5 3.4 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2C)c1C nan
16011802 46175 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 6 3.4 COc1ccc(C(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1OC nan
CHEMBL1534572 46175 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 6 3.4 COc1ccc(C(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1OC nan
3410008 46195 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 2 5 2.8 CCOc1ccc(N/C=C2/C(=O)NC(=S)N(Cc3ccccc3)C2=O)cc1 nan
CHEMBL1534800 46195 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 2 5 2.8 CCOc1ccc(N/C=C2/C(=O)NC(=S)N(Cc3ccccc3)C2=O)cc1 nan
5949916 46237 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 4 4.0 Cc1[nH]c2nc(SCC(=O)c3ccccc3)nc-2cc1Br nan
CHEMBL1535293 46237 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 4 4.0 Cc1[nH]c2nc(SCC(=O)c3ccccc3)nc-2cc1Br nan
2820834 46248 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 7 5.6 CSc1sc(-c2nnc(SCC(=O)Nc3ccc(Cl)cc3)n2C)c2c1C=CCC2 nan
CHEMBL1535400 46248 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 7 5.6 CSc1sc(-c2nnc(SCC(=O)Nc3ccc(Cl)cc3)n2C)c2c1C=CCC2 nan
16019886 46315 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 3.2 Cc1cccc(NC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCCC4)cc32)c1C nan
CHEMBL1536151 46315 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 3.2 Cc1cccc(NC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCCC4)cc32)c1C nan
891752 46375 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 4 3.6 COc1cc(Cl)c(C)cc1NC(=O)c1ccc2c(c1)OCO2 nan
CHEMBL1536712 46375 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 4 3.6 COc1cc(Cl)c(C)cc1NC(=O)c1ccc2c(c1)OCO2 nan
664078 46669 2 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 1 4 3.3 COc1cccc(OCc2nc3cc(Br)c[nH]c-3n2)c1 nan
CHEMBL1539150 46669 2 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 1 4 3.3 COc1cccc(OCc2nc3cc(Br)c[nH]c-3n2)c1 nan
841141 47020 10 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 5 2.2 COC(=O)c1c(NC(=O)c2ccccc2)sc(C(N)=O)c1C nan
CHEMBL1542119 47020 10 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 5 2.2 COC(=O)c1c(NC(=O)c2ccccc2)sc(C(N)=O)c1C nan
664933 47182 11 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.6 Cc1nc(SCC(=O)Nc2ccc(F)cc2)c2oc3ccccc3c2n1 nan
CHEMBL1543543 47182 11 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.6 Cc1nc(SCC(=O)Nc2ccc(F)cc2)c2oc3ccccc3c2n1 nan
3240821 47254 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 8 2.9 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(C(=O)c2ccco2)CC1 nan
CHEMBL1544051 47254 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 8 2.9 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(C(=O)c2ccco2)CC1 nan
1861702 47311 8 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 8 2.7 CC(C)OC(=O)CSc1nc(N)c(C#N)c(-c2ccco2)c1C#N nan
CHEMBL1544436 47311 8 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 8 2.7 CC(C)OC(=O)CSc1nc(N)c(C#N)c(-c2ccco2)c1C#N nan
3164596 47440 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 2.7 COc1ccc2cc(C(=O)NCc3ccccc3)c(=O)oc2c1 nan
CHEMBL1545409 47440 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 2.7 COc1ccc2cc(C(=O)NCc3ccccc3)c(=O)oc2c1 nan
4340721 47494 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 4.0 COc1ccc2cc(C#N)c(Nc3cccc(F)c3)nc2c1 nan
CHEMBL1545865 47494 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 4.0 COc1ccc2cc(C#N)c(Nc3cccc(F)c3)nc2c1 nan
2106365 47497 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 1 5 4.1 Oc1nc(-c2cccnc2)nc2sc(-c3ccccc3)cc12 nan
CHEMBL1545901 47497 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 1 5 4.1 Oc1nc(-c2cccnc2)nc2sc(-c3ccccc3)cc12 nan
902245 47644 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 3 1 3 4.9 CCc1cc2cc(C(=O)Nc3ccc(F)cc3)sc2s1 nan
CHEMBL1547204 47644 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 3 1 3 4.9 CCc1cc2cc(C(=O)Nc3ccc(F)cc3)sc2s1 nan
1088622 47674 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 9 1.2 CCOc1ccc(-c2c(C#N)c(N)nc3c2c(=O)n(C)c(=O)n3C)cc1OC nan
CHEMBL1547487 47674 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 9 1.2 CCOc1ccc(-c2c(C#N)c(N)nc3c2c(=O)n(C)c(=O)n3C)cc1OC nan
2801256 47813 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 1 5 2.4 Cc1nc(-c2cc(C#N)c(O)nc2C)cs1 nan
CHEMBL1548830 47813 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 1 5 2.4 Cc1nc(-c2cc(C#N)c(O)nc2C)cs1 nan
4601866 47924 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 10 3 6 3.4 NS(=O)(=O)c1ccc(CCNC(=O)CCCCCn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 nan
CHEMBL1549770 47924 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 10 3 6 3.4 NS(=O)(=O)c1ccc(CCNC(=O)CCCCCn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 nan
2731089 47972 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 2 7 2.6 COc1ccc(CCNC(=S)NC(=O)c2cc(OC)c(OC)c(OC)c2)cc1OC nan
CHEMBL1550121 47972 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 2 7 2.6 COc1ccc(CCNC(=S)NC(=O)c2cc(OC)c(OC)c(OC)c2)cc1OC nan
5122884 48004 5 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 2.8 COc1ccc2cc(CCN3C(=O)c4ccccc4C3=O)c(O)nc2c1 nan
CHEMBL1550382 48004 5 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 2.8 COc1ccc2cc(CCN3C(=O)c4ccccc4C3=O)c(O)nc2c1 nan
1490541 48010 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 3 4.2 Cc1ccccc1CNc1ncnc2cc(Cl)ccc12 nan
CHEMBL1550435 48010 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 3 4.2 Cc1ccccc1CNc1ncnc2cc(Cl)ccc12 nan
15944825 48072 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 1 5 4.2 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1550942 48072 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 1 5 4.2 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
15988480 48090 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 6 2.4 COC(=O)c1cc(Cl)ccc1NC(=O)Cn1c(C)cc(C)c(C#N)c1=O nan
CHEMBL1551156 48090 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 6 2.4 COC(=O)c1cc(Cl)ccc1NC(=O)Cn1c(C)cc(C)c(C#N)c1=O nan
16025269 48093 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 2 5 4.7 COC(=O)c1c(SCC(=O)Nc2ccccc2C(F)(F)F)[nH]c2ccc(Cl)cc2c1=O nan
CHEMBL1551199 48093 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 2 5 4.7 COC(=O)c1c(SCC(=O)Nc2ccccc2C(F)(F)F)[nH]c2ccc(Cl)cc2c1=O nan
16009432 48108 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 6 3.9 Cc1cccc(C(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)c1 nan
CHEMBL1551357 48108 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 6 3.9 Cc1cccc(C(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)c1 nan
3151519 48111 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 8 3 8 1.4 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccccc4)c(=N)n(CCOCCO)c3nc12 nan
CHEMBL1551451 48111 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 8 3 8 1.4 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccccc4)c(=N)n(CCOCCO)c3nc12 nan
16007408 48117 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 2 3 3.7 Cc1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1F nan
CHEMBL1551538 48117 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 2 3 3.7 Cc1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1F nan
16021062 48127 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 1 6 3.5 COC(=O)c1ccccc1NC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 nan
CHEMBL1551793 48127 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 1 6 3.5 COC(=O)c1ccccc1NC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 nan
1189625 48134 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.3 CCOc1ccc(C(=O)Nc2c(C(=O)c3ccc(OC)cc3)oc3ccccc23)cc1 nan
CHEMBL1551857 48134 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.3 CCOc1ccc(C(=O)Nc2c(C(=O)c3ccc(OC)cc3)oc3ccccc23)cc1 nan
16008906 48141 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 5 3.0 COc1cccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
CHEMBL1551951 48141 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 5 3.0 COc1cccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
16011042 48151 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 2 3 4.8 O=C(Nc1ccc(F)cc1)c1ccc2c(c1)NC(=O)c1ccccc1S2 nan
CHEMBL1552027 48151 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 2 3 4.8 O=C(Nc1ccc(F)cc1)c1ccc2c(c1)NC(=O)c1ccccc1S2 nan
4412264 48152 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 0 8 4.5 CCOC(=O)CSc1nc2c(sc3cccc(F)c32)c(=O)n1Cc1ccc(OC)cc1 nan
CHEMBL1552040 48152 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 0 8 4.5 CCOC(=O)CSc1nc2c(sc3cccc(F)c32)c(=O)n1Cc1ccc(OC)cc1 nan
1187153 48154 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 3.5 CCOC(=O)c1cnc2c(Cl)c(Cl)ccc2c1NCCN1CCOCC1 nan
CHEMBL1552062 48154 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 3.5 CCOC(=O)c1cnc2c(Cl)c(Cl)ccc2c1NCCN1CCOCC1 nan
16027700 48176 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 8 3.7 Cc1ccc(OCC(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)cc1C nan
CHEMBL1552279 48176 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 8 3.7 Cc1ccc(OCC(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)cc1C nan
16032167 48194 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 2 8 3.5 Cn1c(SCC(=O)Nc2nc3ccccc3s2)ncc(C(=O)Nc2ccc(F)cc2)c1=O nan
CHEMBL1552642 48194 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 2 8 3.5 Cn1c(SCC(=O)Nc2nc3ccccc3s2)ncc(C(=O)Nc2ccc(F)cc2)c1=O nan
16024489 48212 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 5 4.5 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccc(C)c(Cl)c3)c2n1 nan
CHEMBL1552935 48212 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 5 4.5 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccc(C)c(Cl)c3)c2n1 nan
16030793 48213 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 5 5.2 COc1ccccc1-c1cc(NC(=O)COc2ccccc2Cl)n(-c2ccccc2)n1 nan
CHEMBL1552946 48213 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 5 5.2 COc1ccccc1-c1cc(NC(=O)COc2ccccc2Cl)n(-c2ccccc2)n1 nan
16020265 48220 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 6 2.5 Cc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3n(CC(N)=O)c2=O)cc1 nan
CHEMBL1552986 48220 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 6 2.5 Cc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3n(CC(N)=O)c2=O)cc1 nan
16024860 48241 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 4 3.9 O=S(=O)(c1ccc2nc(Nc3ccc(F)cc3)ccc2c1)N1CCCC1 nan
CHEMBL1553226 48241 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 4 3.9 O=S(=O)(c1ccc2nc(Nc3ccc(F)cc3)ccc2c1)N1CCCC1 nan
16014611 48250 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 5 3.1 CSc1ccc(NC(=O)C2CCN(c3ncccn3)CC2)cc1 nan
CHEMBL1553334 48250 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 5 3.1 CSc1ccc(NC(=O)C2CCN(c3ncccn3)CC2)cc1 nan
16018242 48266 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1OC nan
CHEMBL1553551 48266 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1OC nan
16020219 48269 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 4 4.2 Cn1c(=O)c2cc(C(=O)NC3CCCCCC3)sc2c2ccccc21 nan
CHEMBL1553584 48269 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 4 4.2 Cn1c(=O)c2cc(C(=O)NC3CCCCCC3)sc2c2ccccc21 nan
3158758 48271 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 4.2 COc1cc(OC)c(C2Nc3c(C)cccc3-c3cc(C)nn32)cc1OC nan
CHEMBL1553632 48271 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 4.2 COc1cc(OC)c(C2Nc3c(C)cccc3-c3cc(C)nn32)cc1OC nan
15989000 48274 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 1 8 2.8 O=C(CCn1c(=O)c2sccc2n(Cc2ccccc2F)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1553743 48274 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 1 8 2.8 O=C(CCn1c(=O)c2sccc2n(Cc2ccccc2F)c1=O)NCc1ccc2c(c1)OCO2 nan
2580267 48281 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 2.9 Cc1cc(C)cc(NC(=O)COC(=O)c2ccc3c(c2)OCCO3)c1 nan
CHEMBL1553826 48281 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 2.9 Cc1cc(C)cc(NC(=O)COC(=O)c2ccc3c(c2)OCCO3)c1 nan
16033854 48285 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 8 3.1 COC(=O)c1ccc2c(=O)n3nc(Nc4ccc(F)cc4F)sc3nc2c1 nan
CHEMBL1553893 48285 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 8 3.1 COC(=O)c1ccc2c(=O)n3nc(Nc4ccc(F)cc4F)sc3nc2c1 nan
16030113 48300 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 6 3.5 Cc1cccc(CNC(=O)Cn2nc(C)c3nn(-c4ccc(Cl)cc4)c(C)c3c2=O)c1 nan
CHEMBL1554129 48300 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 6 3.5 Cc1cccc(CNC(=O)Cn2nc(C)c3nn(-c4ccc(Cl)cc4)c(C)c3c2=O)c1 nan
4361698 48319 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 540 5 0 8 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC2CCCO2)/c1=N\C(=O)c1cccc(C(F)(F)F)c1 nan
CHEMBL1554379 48319 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 540 5 0 8 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC2CCCO2)/c1=N\C(=O)c1cccc(C(F)(F)F)c1 nan
16282512 48321 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 6 1 5 3.2 Cc1ccc(NC(=O)CN(C)C(=O)COc2ncnc3ccc(Br)cc23)cc1 nan
CHEMBL1554437 48321 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 6 1 5 3.2 Cc1ccc(NC(=O)CN(C)C(=O)COc2ncnc3ccc(Br)cc23)cc1 nan
16009851 48324 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 7 4.2 COc1cccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3sc4ccccc4c32)c1 nan
CHEMBL1554474 48324 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 7 4.2 COc1cccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3sc4ccccc4c32)c1 nan
16011879 48325 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 2 4.1 Cc1ccc(CNC(=O)Cc2csc3ccccc23)cc1 nan
CHEMBL1554476 48325 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 2 4.1 Cc1ccc(CNC(=O)Cc2csc3ccccc23)cc1 nan
15988910 48328 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 5 0 10 2.6 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3cc(=O)n4c(C)cccc4n3)c2=O)c1 nan
CHEMBL1554524 48328 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 5 0 10 2.6 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3cc(=O)n4c(C)cccc4n3)c2=O)c1 nan
16009798 48329 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 1 5 4.8 Fc1cccc(-c2nnn3c2nc(NC2CCCCC2)c2ccccc23)c1 nan
CHEMBL1554525 48329 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 1 5 4.8 Fc1cccc(-c2nnn3c2nc(NC2CCCCC2)c2ccccc23)c1 nan
16019045 48330 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 8 1 7 4.0 CCOc1cc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)ccc1OC nan
CHEMBL1554576 48330 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 8 1 7 4.0 CCOc1cc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)ccc1OC nan
16010240 48344 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 3 5.3 CC(C)c1ccc(NC(=O)c2cc3sc(Cl)cc3n2C)cc1 nan
CHEMBL1554758 48344 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 3 5.3 CC(C)c1ccc(NC(=O)c2cc3sc(Cl)cc3n2C)cc1 nan
16016717 48375 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 2 3 6.0 CCc1ccccc1NC(=O)Nc1ccc2c(c1)N(CC)C(=O)c1ccccc1S2 nan
CHEMBL1555228 48375 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 2 3 6.0 CCc1ccccc1NC(=O)Nc1ccc2c(c1)N(CC)C(=O)c1ccccc1S2 nan
15999699 48377 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 5 3.7 CCCCNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1555241 48377 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 5 3.7 CCCCNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C nan
16024527 48457 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 6 4.2 COc1ccc(C(=O)c2cn(CC(=O)Nc3cc(C)ccc3C)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1556147 48457 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 6 4.2 COc1ccc(C(=O)c2cn(CC(=O)Nc3cc(C)ccc3C)c3nc(C)ccc3c2=O)cc1 nan
884827 48458 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 1 5 3.8 CCOc1ccc(Nc2nc3ccccc3c(=O)s2)cc1 nan
CHEMBL1556149 48458 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 1 5 3.8 CCOc1ccc(Nc2nc3ccccc3c(=O)s2)cc1 nan
1299811 48479 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 0 8 3.4 COC(=O)CSc1ncnc2c1sc1nc3c(cc12)COC(C)(C)C3 nan
CHEMBL1556306 48479 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 0 8 3.4 COC(=O)CSc1ncnc2c1sc1nc3c(cc12)COC(C)(C)C3 nan
1297627 48509 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 1 3 4.1 CC(=O)c1ccc(NC(=S)N2CCN(c3cccc(Cl)c3)CC2)cc1 nan
CHEMBL1556657 48509 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 1 3 4.1 CC(=O)c1ccc(NC(=S)N2CCN(c3cccc(Cl)c3)CC2)cc1 nan
1262055 48511 7 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 5.3 CCn1c(SCC(=O)Nc2cccc(F)c2)nnc1-c1cc2cc(Br)ccc2o1 nan
CHEMBL1556666 48511 7 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 5.3 CCn1c(SCC(=O)Nc2cccc(F)c2)nnc1-c1cc2cc(Br)ccc2o1 nan
2769090 48671 25 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 0 5 2.8 CC(=O)c1cc(C#N)c(N2CCN(c3ccccc3)CC2)nc1C nan
CHEMBL1558006 48671 25 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 0 5 2.8 CC(=O)c1cc(C#N)c(N2CCN(c3ccccc3)CC2)nc1C nan
16015862 48842 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 5.7 Cc1ccc(SCC(=O)Nc2ccc3oc(-c4ccc(F)cc4)nc3c2)cc1 nan
CHEMBL1559463 48842 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 5.7 Cc1ccc(SCC(=O)Nc2ccc3oc(-c4ccc(F)cc4)nc3c2)cc1 nan
3208119 48868 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 4.4 CCc1cc2ccc(C)c(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1559714 48868 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 4.4 CCc1cc2ccc(C)c(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
16286863 49042 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 2 6 2.7 CC(OC(=O)c1cc(Br)ccc1O)C(=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1561413 49042 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 2 6 2.7 CC(OC(=O)c1cc(Br)ccc1O)C(=O)NCc1ccc2c(c1)OCO2 nan
24686491 49200 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 3.2 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)Nc1ccc(C)cn1 nan
CHEMBL1562813 49200 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 3.2 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)Nc1ccc(C)cn1 nan
135884418 49216 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 7 3.9 COc1cc2ccccc2cc1C(=O)OCc1nc(O)c2sccc2n1 nan
CHEMBL1562918 49216 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 7 3.9 COc1cc2ccccc2cc1C(=O)OCc1nc(O)c2sccc2n1 nan
664089 49266 8 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.6 Cc1nc(SCC(=O)Nc2cccc(F)c2)c2oc3ccccc3c2n1 nan
CHEMBL1563407 49266 8 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.6 Cc1nc(SCC(=O)Nc2cccc(F)c2)c2oc3ccccc3c2n1 nan
16008603 49267 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 7 1.5 COc1ccc(CNC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1563417 49267 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 7 1.5 COc1ccc(CNC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 nan
16025580 49315 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 4 1 6 4.6 Cc1cc(C)c(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(C)S3(=O)=O)c(C)c1 nan
CHEMBL1563792 49315 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 4 1 6 4.6 Cc1cc(C)c(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(C)S3(=O)=O)c(C)c1 nan
654285 49432 1 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 6 1.7 N#Cc1cc2cc3c(cc2nc1N1CCOCC1)OCO3 nan
CHEMBL1564877 49432 1 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 6 1.7 N#Cc1cc2cc3c(cc2nc1N1CCOCC1)OCO3 nan
4282255 49534 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 4 1 6 2.6 COc1cc([N+](=O)[O-])cc2sc(NC(=O)C3CC3)nc12 nan
CHEMBL1565614 49534 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 4 1 6 2.6 COc1cc([N+](=O)[O-])cc2sc(NC(=O)C3CC3)nc12 nan
151922 49808 64 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 12 1 1 5.2 O=C(O)CCCCCCCCCCCc1ccccc1 nan
CHEMBL1567811 49808 64 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 12 1 1 5.2 O=C(O)CCCCCCCCCCCc1ccccc1 nan
4289114 49931 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 4 6.0 Cc1ccc(C(=O)c2oc3ccccc3c2NC(=O)C(C)Oc2ccccc2Cl)cc1 nan
CHEMBL1568822 49931 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 4 6.0 Cc1ccc(C(=O)c2oc3ccccc3c2NC(=O)C(C)Oc2ccccc2Cl)cc1 nan
650090 49962 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 0 9 2.7 Cn1c(=O)c2c(nc(SCC(=O)c3cccs3)n2Cc2ccc(F)cc2)n(C)c1=O nan
CHEMBL1569069 49962 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 0 9 2.7 Cn1c(=O)c2c(nc(SCC(=O)c3cccs3)n2Cc2ccc(F)cc2)n(C)c1=O nan
1336265 50100 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 2 6 2.5 COC(=O)c1sc(NC(=S)NC(=O)c2ccccc2F)nc1C nan
CHEMBL1570262 50100 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 2 6 2.5 COC(=O)c1sc(NC(=S)NC(=O)c2ccccc2F)nc1C nan
1834757 50141 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 5 6.7 CCN(CC)c1ccc2cc(-c3nc(-c4ccc(Cl)cc4Cl)cs3)c(=O)oc2c1 nan
CHEMBL1570631 50141 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 5 6.7 CCN(CC)c1ccc2cc(-c3nc(-c4ccc(Cl)cc4Cl)cs3)c(=O)oc2c1 nan
661116 50219 8 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 8 3.2 COc1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 nan
CHEMBL1571331 50219 8 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 8 3.2 COc1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 nan
3228933 50279 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 8 3.5 CCc1nc(SCC(=O)Nc2c(C)nn(C)c2C)c2cnn(-c3ccccc3)c2n1 nan
CHEMBL1571990 50279 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 8 3.5 CCc1nc(SCC(=O)Nc2c(C)nn(C)c2C)c2cnn(-c3ccccc3)c2n1 nan
998563 50289 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 3 5.8 Cc1ccc(NC(=O)c2cc(-c3cccs3)nc3ccccc23)c(C)c1 nan
CHEMBL1572046 50289 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 3 5.8 Cc1ccc(NC(=O)c2cc(-c3cccs3)nc3ccccc23)c(C)c1 nan
5038692 50327 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 1.9 O=C(O)C1Cc2ccccc2CN1C(=O)CSc1nnc2ccccn12 nan
CHEMBL1572334 50327 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 1.9 O=C(O)C1Cc2ccccc2CN1C(=O)CSc1nnc2ccccn12 nan
16020271 50601 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 7 1 6 5.1 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(Cc3cccc(Cl)c3)c2=O)cc1 nan
CHEMBL1575057 50601 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 7 1 6 5.1 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(Cc3cccc(Cl)c3)c2=O)cc1 nan
1637692 50613 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 1 5 4.1 CC(=O)c1sc(NC(=O)CCCOc2ccc(Cl)cc2)nc1C nan
CHEMBL1575283 50613 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 1 5 4.1 CC(=O)c1sc(NC(=O)CCCOc2ccc(Cl)cc2)nc1C nan
2446441 50883 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 2 2 4.2 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)cc2Br)c1C nan
CHEMBL1577640 50883 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 2 2 4.2 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)cc2Br)c1C nan
2868371 50908 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 6 2 7 2.5 CCOc1ccccc1NC(=O)CSc1nc(N)c(C#N)cc1C#N nan
CHEMBL1577894 50908 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 6 2 7 2.5 CCOc1ccccc1NC(=O)CSc1nc(N)c(C#N)cc1C#N nan
7207360 50912 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 7 3.4 CCOC(=O)c1ccc(NC(=O)CSc2ccc(-c3ccncc3)nn2)cc1 nan
CHEMBL1577921 50912 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 7 3.4 CCOC(=O)c1ccc(NC(=O)CSc2ccc(-c3ccncc3)nn2)cc1 nan
24891931 50992 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 2 7 0.7 NS(=O)(=O)c1ccc(CCNC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)cc1 nan
CHEMBL1578510 50992 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 2 7 0.7 NS(=O)(=O)c1ccc(CCNC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)cc1 nan
712274 51030 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 3 5 2.2 NC(=O)c1ccc2nc(NC(=O)c3ccc(N)cc3)sc2c1 nan
CHEMBL1578798 51030 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 3 5 2.2 NC(=O)c1ccc2nc(NC(=O)c3ccc(N)cc3)sc2c1 nan
7416477 51181 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 4 3.5 Cc1cccc(C(=O)OCC(=O)c2cccc(Br)c2)c1O nan
CHEMBL1580196 51181 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 4 3.5 Cc1cccc(C(=O)OCC(=O)c2cccc(Br)c2)c1O nan
16193583 51210 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 10 1 8 3.3 CCCCNC(=O)CSc1nc2ccc(N3CCOCC3)cc2c(=O)n1Cc1ccc(OC)cc1 nan
CHEMBL1580449 51210 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 10 1 8 3.3 CCCCNC(=O)CSc1nc2ccc(N3CCOCC3)cc2c(=O)n1Cc1ccc(OC)cc1 nan
135421577 51255 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 3 2 3 2.0 C=CCN1C(=O)/C(=C/c2cc3ccccc3[nH]2)C(=O)NC1=S nan
CHEMBL1580833 51255 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 3 2 3 2.0 C=CCN1C(=O)/C(=C/c2cc3ccccc3[nH]2)C(=O)NC1=S nan
652265 51310 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 4.1 O=C(Nc1ccc(Oc2ccccc2)cc1)C1CCN(c2ncccn2)CC1 nan
CHEMBL1581276 51310 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 4.1 O=C(Nc1ccc(Oc2ccccc2)cc1)C1CCN(c2ncccn2)CC1 nan
4455225 51399 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 9 2 5 3.5 CCOCCCn1c(=S)[nH]c2cc(C(=O)NCCc3ccccc3)ccc2c1=O nan
CHEMBL1582016 51399 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 9 2 5 3.5 CCOCCCn1c(=S)[nH]c2cc(C(=O)NCCc3ccccc3)ccc2c1=O nan
135693216 51651 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 5 2.9 Cc1cccc(CCNC(=O)Cn2ncc3c4ccccc4nc-3c2O)c1 nan
CHEMBL1584056 51651 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 5 2.9 Cc1cccc(CCNC(=O)Cn2ncc3c4ccccc4nc-3c2O)c1 nan
3662539 51674 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 1 4 7 3.1 N#Cc1c(N)nc2c3c(sc(=N)c2c1N)NC(=O)CC3c1c(F)cccc1Cl nan
CHEMBL1584309 51674 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 1 4 7 3.1 N#Cc1c(N)nc2c3c(sc(=N)c2c1N)NC(=O)CC3c1c(F)cccc1Cl nan
24819718 51806 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 2 4.0 O=C(c1cc2ccccc2cc1O)N1CCCC(C(F)(F)F)C1 nan
CHEMBL1585344 51806 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 2 4.0 O=C(c1cc2ccccc2cc1O)N1CCCC(C(F)(F)F)C1 nan
2112635 51959 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 2 6 2.9 Cc1nc(NCc2ccc(S(N)(=O)=O)cc2)c2c(C)c(C)sc2n1 nan
CHEMBL1586644 51959 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 2 6 2.9 Cc1nc(NCc2ccc(S(N)(=O)=O)cc2)c2c(C)c(C)sc2n1 nan
135441025 51973 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 2 4 3.7 CCCn1c(=O)c(-c2nc3ccccc3[nH]2)c(O)c2ccccc21 nan
CHEMBL1586724 51973 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 2 4 3.7 CCCn1c(=O)c(-c2nc3ccccc3[nH]2)c(O)c2ccccc21 nan
2158327 52015 11 None -17 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 3.9 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccc(F)cc1 nan
CHEMBL1587044 52015 11 None -17 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 3.9 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccc(F)cc1 nan
20876043 52187 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 8 0.5 COc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)c1 nan
CHEMBL1588535 52187 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 8 0.5 COc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)c1 nan
16016041 52338 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 4 4.5 COc1ccc(CC(=O)Nc2nc3c(s2)CC(C(C)(C)C)CC3)cc1 nan
CHEMBL1589883 52338 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 4 4.5 COc1ccc(CC(=O)Nc2nc3c(s2)CC(C(C)(C)C)CC3)cc1 nan
4671465 52363 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 2 4 3.3 NC(=O)c1ccc(NC(=O)c2ccc(COc3ccc(F)cc3)o2)cc1 nan
CHEMBL1590137 52363 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 2 4 3.3 NC(=O)c1ccc(NC(=O)c2ccc(COc3ccc(F)cc3)o2)cc1 nan
16009149 52393 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 3 5.5 Cc1ccc(CNC(=O)CSc2c3c(nc4cc(Cl)ccc24)CCCC3)cc1 nan
CHEMBL1590589 52393 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 3 5.5 Cc1ccc(CNC(=O)CSc2c3c(nc4cc(Cl)ccc24)CCCC3)cc1 nan
16026741 52401 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 0 8 2.8 O=C(COc1ccc(Cl)cc1)OCc1cc(=O)n2nc(C3CC3)sc2n1 nan
CHEMBL1590675 52401 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 0 8 2.8 O=C(COc1ccc(Cl)cc1)OCc1cc(=O)n2nc(C3CC3)sc2n1 nan
16025957 52407 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 8 1.6 O=C(NCc1ccc(Cl)cc1)c1cnc2sc(N3CCOCC3)nn2c1=O nan
CHEMBL1590760 52407 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 8 1.6 O=C(NCc1ccc(Cl)cc1)c1cnc2sc(N3CCOCC3)nn2c1=O nan
16033877 52408 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 8 4.0 O=C(NCc1cccs1)c1ccc2c(=O)n3nc(Nc4ccccc4)sc3nc2c1 nan
CHEMBL1590761 52408 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 8 4.0 O=C(NCc1cccs1)c1ccc2c(=O)n3nc(Nc4ccccc4)sc3nc2c1 nan
18567961 52425 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 9 2 6 3.3 COc1ccc(C(=O)Nc2nc(CC(=O)NCCc3ccccc3OC)cs2)cc1 nan
CHEMBL1590928 52425 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 9 2 6 3.3 COc1ccc(C(=O)Nc2nc(CC(=O)NCCc3ccccc3OC)cs2)cc1 nan
16021437 52452 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 2 4 6.6 Cc1cc(Nc2cccc(Cl)c2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 nan
CHEMBL1591314 52452 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 2 4 6.6 Cc1cc(Nc2cccc(Cl)c2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 nan
16030267 52465 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 0 4 4.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCCCC2)cc1 nan
CHEMBL1591398 52465 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 0 4 4.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCCCC2)cc1 nan
15988978 52466 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 1 7 3.9 COc1ccc(NC(=O)Cn2c(=O)n(-c3cccc(C(F)(F)F)c3)c(=O)c3sccc32)cc1 nan
CHEMBL1591409 52466 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 1 7 3.9 COc1ccc(NC(=O)Cn2c(=O)n(-c3cccc(C(F)(F)F)c3)c(=O)c3sccc32)cc1 nan
4905426 52469 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.4 COc1ccc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2c1 nan
CHEMBL1591442 52469 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.4 COc1ccc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2c1 nan
15989516 52510 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 9 2 6 4.0 O=C(Cn1c(=O)n(CC2CCC(C(=O)NCCc3ccccc3)CC2)c(=O)c2ccccc21)Nc1ccccc1 nan
CHEMBL1592027 52510 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 9 2 6 4.0 O=C(Cn1c(=O)n(CC2CCC(C(=O)NCCc3ccccc3)CC2)c(=O)c2ccccc21)Nc1ccccc1 nan
15991260 52530 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 2 7 1.4 CCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
CHEMBL1592271 52530 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 2 7 1.4 CCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
16027708 52553 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 7 4.7 CC(C)(C)c1ccc(C(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1592618 52553 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 7 4.7 CC(C)(C)c1ccc(C(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)cc1 nan
16027669 52554 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 1 7 4.9 O=C(Nc1ccccc1C(=O)OCc1cc(=O)n2c3c(sc2n1)CCCC3)c1cccc(Cl)c1 nan
CHEMBL1592645 52554 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 1 7 4.9 O=C(Nc1ccccc1C(=O)OCc1cc(=O)n2c3c(sc2n1)CCCC3)c1cccc(Cl)c1 nan
16024581 52565 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 5 3.7 Cc1ccc(CNC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc1 nan
CHEMBL1592799 52565 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 5 3.7 Cc1ccc(CNC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc1 nan
16020979 52596 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 7 4.5 COc1cc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc(OC)c1 nan
CHEMBL1593212 52596 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 7 4.5 COc1cc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc(OC)c1 nan
16012982 52610 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 3 5.7 Cc1cccc(N(Cc2cc3ccccc3nc2O)C(=O)c2cccc(Cl)c2)c1 nan
CHEMBL1593385 52610 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 3 5.7 Cc1cccc(N(Cc2cc3ccccc3nc2O)C(=O)c2cccc(Cl)c2)c1 nan
5143379 52611 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 2 3 5.0 CC(=O)Nc1cc(C(=O)NCc2ccc(F)cc2)ccc1Sc1ccc(F)cc1 nan
CHEMBL1593424 52611 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 2 3 5.0 CC(=O)Nc1cc(C(=O)NCc2ccc(F)cc2)ccc1Sc1ccc(F)cc1 nan
16322180 52627 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 5 3.7 Cc1nc(SC(C)C(=O)NC2(C#N)CCCCC2)c(C#N)c(C)c1C nan
CHEMBL1593705 52627 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 5 3.7 Cc1nc(SC(C)C(=O)NC2(C#N)CCCCC2)c(C#N)c(C)c1C nan
16024549 52633 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 6 4.6 CCOc1ccccc1NC(=O)Cn1cc(C(=O)c2ccc(Cl)cc2)c(=O)c2ccc(C)nc21 nan
CHEMBL1593798 52633 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 6 4.6 CCOc1ccccc1NC(=O)Cn1cc(C(=O)c2ccc(Cl)cc2)c(=O)c2ccc(C)nc21 nan
16019841 52637 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 7 4.1 CC(C)Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3Cl)nnc12 nan
CHEMBL1593835 52637 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 7 4.1 CC(C)Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3Cl)nnc12 nan
16026849 52644 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 1 5 3.8 COc1ccc(Cn2ccc3nc(C)c(C(=O)NCc4ccc(F)cc4)cc3c2=O)cc1 nan
CHEMBL1593965 52644 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 1 5 3.8 COc1ccc(Cn2ccc3nc(C)c(C(=O)NCc4ccc(F)cc4)cc3c2=O)cc1 nan
16024916 52650 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 4.9 CSc1ccc(CCNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1594028 52650 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 4.9 CSc1ccc(CCNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16024610 52660 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 4.8 CCc1ccc(C(=O)c2cn(CC(=O)Nc3cccc(C)c3C)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1594130 52660 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 4.8 CCc1ccc(C(=O)c2cn(CC(=O)Nc3cccc(C)c3C)c3nc(C)ccc3c2=O)cc1 nan
2140504 52806 20 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 6 3.4 N#Cc1cc2c(nc1SCC(=O)Nc1nccs1)CCCCC2 nan
CHEMBL1595336 52806 20 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 6 3.4 N#Cc1cc2c(nc1SCC(=O)Nc1nccs1)CCCCC2 nan
16024587 52889 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 5 3.4 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccccc3)c2n1 nan
CHEMBL1596100 52889 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 5 3.4 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccccc3)c2n1 nan
865538 52927 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 3 1 3 4.0 Cc1ccc2nc(NCc3ccccc3)c(C#N)cc2c1 nan
CHEMBL1596421 52927 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 3 1 3 4.0 Cc1ccc2nc(NCc3ccccc3)c(C#N)cc2c1 nan
16008803 52938 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 4 5.8 CCOc1ccccc1NC(=O)c1cc2c(Cl)nc3ccccc3c2s1 nan
CHEMBL1596557 52938 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 4 5.8 CCOc1ccccc1NC(=O)c1cc2c(Cl)nc3ccccc3c2s1 nan
1191858 52946 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 0 6 3.8 COc1ccc(-c2cc(=O)c3cc(OCC(=O)OC(C)C)ccc3o2)cc1 nan
CHEMBL1596612 52946 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 0 6 3.8 COc1ccc(-c2cc(=O)c3cc(OCC(=O)OC(C)C)ccc3o2)cc1 nan
16011437 52950 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 10 1 6 5.8 COc1ccc(Cn2c(SCc3ccc(C(=O)NCCc4ccccc4)cc3)nc3cccnc32)cc1 nan
CHEMBL1596645 52950 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 10 1 6 5.8 COc1ccc(Cn2c(SCc3ccc(C(=O)NCCc4ccccc4)cc3)nc3cccnc32)cc1 nan
2110721 52969 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 2 2 3.5 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(F)c(F)c2F)c1C nan
CHEMBL1596828 52969 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 2 2 3.5 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(F)c(F)c2F)c1C nan
15991384 53005 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 4 6.2 COc1c(C)cccc1C(=O)Nc1ccc(-c2nc3ccccc3s2)c(Cl)c1 nan
CHEMBL1597164 53005 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 4 6.2 COc1c(C)cccc1C(=O)Nc1ccc(-c2nc3ccccc3s2)c(Cl)c1 nan
9397360 53183 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 8 3.6 CCc1nnc(NC(=O)C2CCN(c3ncnc4sc(C)c(C)c34)CC2)s1 nan
CHEMBL1598832 53183 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 8 3.6 CCc1nnc(NC(=O)C2CCN(c3ncnc4sc(C)c(C)c34)CC2)s1 nan
1873710 53205 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 5 5.3 CCOc1nc(-c2ccc(C)cc2)ccc1-c1noc(-c2ccccc2F)n1 nan
CHEMBL1599008 53205 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 5 5.3 CCOc1nc(-c2ccc(C)cc2)ccc1-c1noc(-c2ccccc2F)n1 nan
16016553 53225 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 5 4.1 Cc1cc(C)cc(OCC(=O)Nc2nonc2-c2ccc(Br)cc2)c1 nan
CHEMBL1599164 53225 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 5 4.1 Cc1cc(C)cc(OCC(=O)Nc2nonc2-c2ccc(Br)cc2)c1 nan
16027417 53245 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 8 4.1 Cc1csc2nc(COC(=O)c3cccc(NC(=O)COc4ccccc4Cl)c3)cc(=O)n12 nan
CHEMBL1599306 53245 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 8 4.1 Cc1csc2nc(COC(=O)c3cccc(NC(=O)COc4ccccc4Cl)c3)cc(=O)n12 nan
5059359 53313 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 2 0 6 4.4 Cn1c(=O)c2c(-c3ccccc3)n3c4ccccc4nc(-c4ccccc4)c3c2n(C)c1=O nan
CHEMBL1599921 53313 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 2 0 6 4.4 Cn1c(=O)c2c(-c3ccccc3)n3c4ccccc4nc(-c4ccccc4)c3c2n(C)c1=O nan
16019821 53394 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 2 6 3.4 CCOc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
CHEMBL1600701 53394 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 2 6 3.4 CCOc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
16021830 53523 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.4 CSc1ncc(C(=O)Nc2ccc(F)cc2F)c(-c2ccccc2)n1 nan
CHEMBL1602038 53523 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.4 CSc1ncc(C(=O)Nc2ccc(F)cc2F)c(-c2ccccc2)n1 nan
4197620 53544 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 1 6 2.7 COc1ccc(Cl)cc1NC(=O)c1cnc2sccn2c1=O nan
CHEMBL1602236 53544 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 1 6 2.7 COc1ccc(Cl)cc1NC(=O)c1cnc2sccn2c1=O nan
16026568 53578 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 4.8 Cc1cc(C)c(NC(=O)C(C)n2c(=O)cc(-c3ccccc3)c3c(C)nn(C)c32)c(C)c1 nan
CHEMBL1602546 53578 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 4.8 Cc1cc(C)c(NC(=O)C(C)n2c(=O)cc(-c3ccccc3)c3c(C)nn(C)c32)c(C)c1 nan
1482197 53609 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 5 0 4 4.0 COc1ccc(C(=O)c2ccc(-c3ccc(OC)cc3)nc2)cc1 nan
CHEMBL1602835 53609 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 5 0 4 4.0 COc1ccc(C(=O)c2ccc(-c3ccc(OC)cc3)nc2)cc1 nan
16023008 53623 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 7 4.1 COc1ccc(-n2nc3c(N4CCC(C(=O)NCc5cccc(F)c5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1602958 53623 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 7 4.1 COc1ccc(-n2nc3c(N4CCC(C(=O)NCc5cccc(F)c5)CC4)nnc(C)c3c2C)cc1 nan
4077604 53689 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.1 O=C(NCC1CCCO1)c1ccc2c(=O)n(-c3ccc(F)cc3)c(=S)[nH]c2c1 nan
CHEMBL1603522 53689 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.1 O=C(NCC1CCCO1)c1ccc2c(=O)n(-c3ccc(F)cc3)c(=S)[nH]c2c1 nan
16008430 53766 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 6 0 6 5.0 COc1ccc(N2CCN(C(=O)CCc3c(C)nc4cc(-c5ccc(Cl)cc5)nn4c3C)CC2)cc1 nan
CHEMBL1604039 53766 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 6 0 6 5.0 COc1ccc(N2CCN(C(=O)CCc3c(C)nc4cc(-c5ccc(Cl)cc5)nn4c3C)CC2)cc1 nan
2319103 53776 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 7 2 6 4.7 CC(=O)Nc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3ccc(F)cc3)cc2)cc1 nan
CHEMBL1604161 53776 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 7 2 6 4.7 CC(=O)Nc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3ccc(F)cc3)cc2)cc1 nan
1105833 53835 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 2 0 2 5.2 N#Cc1c(-c2cccc(F)c2)cc(-c2ccccc2)nc1Br nan
CHEMBL1604724 53835 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 2 0 2 5.2 N#Cc1c(-c2cccc(F)c2)cc(-c2ccccc2)nc1Br nan
13283806 53949 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 3 4.2 O=S1(=O)c2ccccc2N(Cc2ccccc2)c2ccccc21 nan
CHEMBL1605626 53949 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 3 4.2 O=S1(=O)c2ccccc2N(Cc2ccccc2)c2ccccc21 nan
606829 54031 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 1 2 5.1 Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1606319 54031 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 1 2 5.1 Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 nan
2877673 54071 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 0 4 4.3 CCCC(=O)N1CCN(c2ccc(C(=O)c3ccc(OC)c(Br)c3)cc2F)CC1 nan
CHEMBL1606636 54071 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 0 4 4.3 CCCC(=O)N1CCN(c2ccc(C(=O)c3ccc(OC)c(Br)c3)cc2F)CC1 nan
16025505 54135 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 4.1 CC(C)c1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(C)S3(=O)=O)cc1 nan
CHEMBL1607091 54135 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 4.1 CC(C)c1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(C)S3(=O)=O)cc1 nan
16019209 54149 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 7 4.2 COc1ccc(Cn2c(=O)c3oc4ccccc4c3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1 nan
CHEMBL1607174 54149 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 7 4.2 COc1ccc(Cn2c(=O)c3oc4ccccc4c3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1 nan
1166591 54248 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 5 5.4 COc1ccc(-c2cc(C(F)(F)F)nc(SCCC(=O)Nc3ccccc3F)n2)cc1 nan
CHEMBL1608012 54248 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 5 5.4 COc1ccc(-c2cc(C(F)(F)F)nc(SCCC(=O)Nc3ccccc3F)n2)cc1 nan
939124 54470 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 6 3.6 CC(=O)c1c(C)nc(Nc2nc3ccccc3s2)nc1C nan
CHEMBL1609840 54470 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 6 3.6 CC(=O)c1c(C)nc(Nc2nc3ccccc3s2)nc1C nan
15989162 54500 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 542 10 2 7 3.8 COc1ccccc1CNC(=O)CCCn1c(=O)c2ccccc2n(CC(=O)Nc2c(C)cc(C)cc2C)c1=O nan
CHEMBL1610075 54500 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 542 10 2 7 3.8 COc1ccccc1CNC(=O)CCCn1c(=O)c2ccccc2n(CC(=O)Nc2c(C)cc(C)cc2C)c1=O nan
2542807 54537 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 1 4 4.2 Cc1cc(C)c(NC(=O)CSc2nc(C)cc(C)c2C#N)c(C)c1 nan
CHEMBL1610420 54537 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 1 4 4.2 Cc1cc(C)c(NC(=O)CSc2nc(C)cc(C)c2C#N)c(C)c1 nan
1192919 54666 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.1 COc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2ccc(F)cc2)cc1 nan
CHEMBL1611527 54666 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.1 COc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2ccc(F)cc2)cc1 nan
16024853 54787 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 4 4.2 O=C(NCCc1ccccc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1612612 54787 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 4 4.2 O=C(NCCc1ccccc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
24789826 55035 0 None -56 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 4 5.8 CCN(CC)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1307717 55035 0 None -56 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 4 5.8 CCN(CC)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1616626 55035 0 None -56 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 4 5.8 CCN(CC)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
135448704 55229 34 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 4 4 1.4 N=C(N)Nc1nc(O)c2cc(Br)ccc2n1 nan
CHEMBL1319156 55229 34 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 4 4 1.4 N=C(N)Nc1nc(O)c2cc(Br)ccc2n1 nan
CHEMBL1618027 55229 34 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 4 4 1.4 N=C(N)Nc1nc(O)c2cc(Br)ccc2n1 nan
3773369 55687 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 5 2.9 COc1ccc(CCn2c(S)nc3ccccc3c2=O)cc1 nan
CHEMBL1483432 55687 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 5 2.9 COc1ccc(CCn2c(S)nc3ccccc3c2=O)cc1 nan
CHEMBL1622111 55687 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 5 2.9 COc1ccc(CCn2c(S)nc3ccccc3c2=O)cc1 nan
6886091 107833 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 3 1 6 3.2 Cn1c(=O)n(C)c2cc(/C=N/NC(=O)c3cc4cc(Br)ccc4o3)ccc21 nan
CHEMBL3192586 107833 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 3 1 6 3.2 Cn1c(=O)n(C)c2cc(/C=N/NC(=O)c3cc4cc(Br)ccc4o3)ccc21 nan
3221539 107892 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 8 0 6 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\CCOC)S3 nan
CHEMBL3193316 107892 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 8 0 6 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\CCOC)S3 nan
9615796 108221 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.3 Cn1c(=O)n(C)c2cc(/C=N/NC(=O)c3ccc(Cl)cc3)ccc21 nan
CHEMBL3197069 108221 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.3 Cn1c(=O)n(C)c2cc(/C=N/NC(=O)c3ccc(Cl)cc3)ccc21 nan
24892226 108311 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 0 9 2.2 COC(=O)Cn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2c(OC)ccc(OC)c21 nan
CHEMBL3197975 108311 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 0 9 2.2 COC(=O)Cn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2c(OC)ccc(OC)c21 nan
6341421 108363 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 3 1 3 3.6 CCCn1c(C)cs/c1=N\C(=S)Nc1ccccc1 nan
CHEMBL3198424 108363 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 3 1 3 3.6 CCCn1c(C)cs/c1=N\C(=S)Nc1ccccc1 nan
6065517 108776 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 5 2 4 1.1 CC(C)NC(=O)CC(=O)N/N=C/c1cccs1 nan
CHEMBL3209441 108776 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 5 2 4 1.1 CC(C)NC(=O)CC(=O)N/N=C/c1cccs1 nan
135485035 108926 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 5 3.9 COc1ccc(Cl)cc1/N=C/c1c(O)oc2ccccc2c1=O nan
CHEMBL3211560 108926 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 5 3.9 COc1ccc(Cl)cc1/N=C/c1c(O)oc2ccccc2c1=O nan
17584634 109129 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 0 5 2.7 COc1ccc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2Cc2ccc(F)cc2)cc1 nan
CHEMBL3214247 109129 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 0 5 2.7 COc1ccc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2Cc2ccc(F)cc2)cc1 nan
6869045 112571 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 7 2 5 1.8 NCCCCCC(=O)N/N=C/c1coc2ccccc2c1=O nan
CHEMBL3194304 112571 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 7 2 5 1.8 NCCCCCC(=O)N/N=C/c1coc2ccccc2c1=O nan
CHEMBL3301898 112571 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 7 2 5 1.8 NCCCCCC(=O)N/N=C/c1coc2ccccc2c1=O nan
658981 117038 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 1 5 2.7 CCOC(=O)c1c(N)sc(=S)c2c1CCC2 nan
CHEMBL3392035 117038 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 1 5 2.7 CCOC(=O)c1c(N)sc(=S)c2c1CCC2 nan
2241546 120385 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 1 4 3.8 Cc1ccc(C(=O)Nc2nc(-c3ccccc3)ns2)cc1 nan
CHEMBL353651 120385 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 1 4 3.8 Cc1ccc(C(=O)Nc2nc(-c3ccccc3)ns2)cc1 nan
878295 173189 33 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 1 1 1 3.8 O=c1cc(-c2ccccc2)c2cc(Cl)ccc2[nH]1 nan
CHEMBL452292 173189 33 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 1 1 1 3.8 O=c1cc(-c2ccccc2)c2cc(Cl)ccc2[nH]1 nan
16010872 199048 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 7 4.4 COc1cc2nc(NCCC(C)C)n3nc(-c4ccccc4)nc3c2cc1OC nan
CHEMBL587492 199048 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 7 4.4 COc1cc2nc(NCCC(C)C)n3nc(-c4ccccc4)nc3c2cc1OC nan
16017892 199107 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 6 3.4 CCOc1ccc(NC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)cc1 nan
CHEMBL589232 199107 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 6 3.4 CCOc1ccc(NC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)cc1 nan
1370186 199657 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 4 4.8 Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ccccc3o2)cc1 nan
CHEMBL593119 199657 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 4 4.8 Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ccccc3o2)cc1 nan
372 58 103 None -107 5 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 4 9 -1.3 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2N nan
8974 58 103 None -107 5 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 4 9 -1.3 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2N nan
CHEMBL285819 58 103 None -107 5 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 4 9 -1.3 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2N nan
16019683 24047 1 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.6 Cc1ccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1338399 24047 1 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.6 Cc1ccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
3486944 24969 10 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 0 4 2.5 Cc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)c(C)n1-c1ccccc1 nan
CHEMBL1346519 24969 10 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 0 4 2.5 Cc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)c(C)n1-c1ccccc1 nan
665622 30122 7 None 3 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 11 2.8 CC1(C)Cc2c(sc3c2c2ncnn2c2nnc(SCC(=O)NCc4ccco4)n32)CO1 nan
CHEMBL1390005 30122 7 None 3 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 11 2.8 CC1(C)Cc2c(sc3c2c2ncnn2c2nnc(SCC(=O)NCc4ccco4)n32)CO1 nan
16019552 35161 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 8 4.1 Cc1ccc(CNc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)cc1 nan
CHEMBL1435107 35161 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 8 4.1 Cc1ccc(CNc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)cc1 nan
665286 35550 9 None 3 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 3.2 CCC1(C)Cc2c(sc3c2c2ncnn2c2nnc(SCC(=O)NCc4ccco4)n32)CO1 nan
CHEMBL1439367 35550 9 None 3 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 3.2 CCC1(C)Cc2c(sc3c2c2ncnn2c2nnc(SCC(=O)NCc4ccco4)n32)CO1 nan
2054021 35774 15 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 7 3.6 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nccs1 nan
CHEMBL1441380 35774 15 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 7 3.6 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nccs1 nan
1395606 35812 9 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 1 5 4.7 CCOc1ccc(-n2nc3ccc(NC(=O)c4ccc(C)cc4C)cc3n2)cc1 nan
CHEMBL1441729 35812 9 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 1 5 4.7 CCOc1ccc(-n2nc3ccc(NC(=O)c4ccc(C)cc4C)cc3n2)cc1 nan
997264 38838 5 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 5 2.9 Cc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 nan
CHEMBL1467097 38838 5 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 5 2.9 Cc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 nan
1552186 39499 17 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 5 1 4 6.8 Cc1ccc2nc(-c3ccc(NC(=O)COc4ccc(Br)cc4Br)cc3)sc2c1 nan
CHEMBL1472916 39499 17 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 5 1 4 6.8 Cc1ccc2nc(-c3ccc(NC(=O)COc4ccc(Br)cc4Br)cc3)sc2c1 nan
16009715 41920 11 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
CHEMBL1494680 41920 11 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
16018178 48221 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.5 Cc1ccc(CNC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)cc1 nan
CHEMBL1552994 48221 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.5 Cc1ccc(CNC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)cc1 nan
15991072 52391 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 1 4 6.3 O=C(Nc1ccc2oc(-c3ccc(Br)cc3)nc2c1)c1cc2ccccc2o1 nan
CHEMBL1590554 52391 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 1 4 6.3 O=C(Nc1ccc2oc(-c3ccc(Br)cc3)nc2c1)c1cc2ccccc2o1 nan
2988582 52580 14 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 1 4 5.1 Cc1cc(-c2nc3ncccc3o2)ccc1NC(=O)c1ccc(Cl)cc1 nan
CHEMBL1592961 52580 14 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 1 4 5.1 Cc1cc(-c2nc3ncccc3o2)ccc1NC(=O)c1ccc(Cl)cc1 nan
15988483 52643 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 2 4 3.7 CC(=O)c1ccc(NC(=O)c2cc3c([nH]c2=O)CC(c2ccccc2)CC3=O)cc1 nan
CHEMBL1593961 52643 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 2 4 3.7 CC(=O)c1ccc(NC(=O)c2cc3c([nH]c2=O)CC(c2ccccc2)CC3=O)cc1 nan
1367050 53954 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 6 3.8 CCOc1ccc(-n2nc3ccc(NC(=O)COc4ccccc4)cc3n2)cc1 nan
CHEMBL1605697 53954 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 6 3.8 CCOc1ccc(-n2nc3ccc(NC(=O)COc4ccccc4)cc3n2)cc1 nan
4429605 71665 12 None -1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 0 7 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(S(=O)(=O)N(C)c3ccccc3)cc2)n(C)c1C nan
CHEMBL1964939 71665 12 None -1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 0 7 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(S(=O)(=O)N(C)c3ccccc3)cc2)n(C)c1C nan
16010338 5845 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 2 8 2.9 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCCNC(C)=O)c2cc(Cl)ccc23)cc1 nan
CHEMBL1079456 5845 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 2 8 2.9 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCCNC(C)=O)c2cc(Cl)ccc23)cc1 nan
135446757 8021 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 2 3.9 O=c1[nH]c(/C=C/c2ccc(Br)cc2)nc2ccccc12 nan
CHEMBL1091028 8021 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 2 3.9 O=c1[nH]c(/C=C/c2ccc(Br)cc2)nc2ccccc12 nan
250997 10458 3 None -12 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 10 3.5 COc1cc(SSc2cc(OC)cc([N+](=O)[O-])c2N)c(N)c([N+](=O)[O-])c1 nan
CHEMBL116548 10458 3 None -12 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 10 3.5 COc1cc(SSc2cc(OC)cc([N+](=O)[O-])c2N)c(N)c([N+](=O)[O-])c1 nan
16019609 10580 10 None -223 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 4.7 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)c2ccccc2)c2sccc23)cc1 nan
CHEMBL1170098 10580 10 None -223 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 4.7 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)c2ccccc2)c2sccc23)cc1 nan
16019288 10659 7 None -234 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 8 4.2 O=S(=O)(c1cccc(Cl)c1)c1nnn2c1nc(NC1CCCC1)c1sccc12 nan
CHEMBL1170696 10659 7 None -234 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 8 4.2 O=S(=O)(c1cccc(Cl)c1)c1nnn2c1nc(NC1CCCC1)c1sccc12 nan
16019546 10678 6 None -676 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 8 3.8 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1sccc12 nan
CHEMBL1170891 10678 6 None -676 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 8 3.8 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1sccc12 nan
16019576 10865 6 None -1995 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 9 3.8 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
CHEMBL1172726 10865 6 None -1995 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 9 3.8 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
7246142 10890 8 None -85 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 8 3.6 CC(C)Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 nan
CHEMBL1172934 10890 8 None -85 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 8 3.6 CC(C)Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 nan
747391 15633 17 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 3.8 CCOC(=O)c1sc(NC(=O)c2ccco2)nc1-c1ccccc1 nan
CHEMBL1222145 15633 17 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 3.8 CCOC(=O)c1sc(NC(=O)c2ccco2)nc1-c1ccccc1 nan
5309696 19526 1 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 6 2.8 CCn1c(=O)cc(OCC(=O)Nc2nc(C)cs2)c2ccccc21 nan
CHEMBL1299766 19526 1 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 6 2.8 CCn1c(=O)cc(OCC(=O)Nc2nc(C)cs2)c2ccccc21 nan
1716419 19601 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 5 4.7 CCCCNC(=O)c1nn2c(C(F)(F)F)cc(-c3ccc(OC)cc3)nc2c1Br nan
CHEMBL1300444 19601 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 5 4.7 CCCCNC(=O)c1nn2c(C(F)(F)F)cc(-c3ccc(OC)cc3)nc2c1Br nan
135468422 19627 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 2 9 4.4 COc1ccc(NC(=O)CSc2nc3nnc(C)c-3c(N)n2-c2ccc(Cl)c(C)c2)cc1OC nan
CHEMBL1300619 19627 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 2 9 4.4 COc1ccc(NC(=O)CSc2nc3nnc(C)c-3c(N)n2-c2ccc(Cl)c(C)c2)cc1OC nan
5112617 19779 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 3 4 2.2 CC(C)CC(=O)NC(=S)Nc1sc2c(c1C(N)=O)CCC2 nan
CHEMBL1301780 19779 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 3 4 2.2 CC(C)CC(=O)NC(=S)Nc1sc2c(c1C(N)=O)CCC2 nan
1440349 19814 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.4 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1c(C)cccc1C)CCC3 nan
CHEMBL1302141 19814 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.4 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1c(C)cccc1C)CCC3 nan
648939 19816 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 3.1 Cc1cc(C)c2cc(C#N)c(SCC(=O)NCC3CCCO3)nc2c1 nan
CHEMBL1302172 19816 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 3.1 Cc1cc(C)c2cc(C#N)c(SCC(=O)NCC3CCCO3)nc2c1 nan
3221134 19858 5 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 6 4.0 COCCN(Cc1cc2cc(C)ccc2n2nnnc12)C(S)=Nc1ccccc1C nan
CHEMBL1302436 19858 5 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 6 4.0 COCCN(Cc1cc2cc(C)ccc2n2nnnc12)C(S)=Nc1ccccc1C nan
1864418 19860 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 6 3.5 CC(C)Cc1nc2sc3c(SCC(N)=O)ncnc3c2c2c1CCC2 nan
CHEMBL1302453 19860 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 6 3.5 CC(C)Cc1nc2sc3c(SCC(N)=O)ncnc3c2c2c1CCC2 nan
22334119 19877 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 8 2 7 2.6 COc1ccc(-n2nc(C(=O)NCC(=O)NCc3ccc(F)cc3)c3ccccc3c2=O)cc1OC nan
CHEMBL1302552 19877 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 8 2 7 2.6 COc1ccc(-n2nc(C(=O)NCC(=O)NCc3ccc(F)cc3)c3ccccc3c2=O)cc1OC nan
1173246 20041 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 2 6 4.2 Cc1ccc(C)c2c1cc(C)c1nnc(SCC(=O)Nc3cccc(C(=O)O)c3)n12 nan
CHEMBL1303849 20041 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 2 6 4.2 Cc1ccc(C)c2c1cc(C)c1nnc(SCC(=O)Nc3cccc(C(=O)O)c3)n12 nan
135455179 20160 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 4 3.0 Cc1cccc(NC2=NC(=O)C(Cc3ccccc3)S2)n1 nan
135480855 20160 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 4 3.0 Cc1cccc(NC2=NC(=O)C(Cc3ccccc3)S2)n1 nan
135554164 20160 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 4 3.0 Cc1cccc(NC2=NC(=O)C(Cc3ccccc3)S2)n1 nan
CHEMBL1304888 20160 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 4 3.0 Cc1cccc(NC2=NC(=O)C(Cc3ccccc3)S2)n1 nan
16188302 20241 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 1 4 5.4 CCN(C(=O)c1cc2c(O)nc3ccc(C)cc3c2s1)c1cccc(C)c1 nan
CHEMBL1305636 20241 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 1 4 5.4 CCN(C(=O)c1cc2c(O)nc3ccc(C)cc3c2s1)c1cccc(C)c1 nan
3612019 20299 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 2 4 2.5 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc(Cl)s1 nan
CHEMBL1305985 20299 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 2 4 2.5 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc(Cl)s1 nan
4243407 20461 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 4.8 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NC(c5ccccc5)c5ccccc5)cnc4c3cc2CO1 nan
CHEMBL1307313 20461 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 4.8 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NC(c5ccccc5)c5ccccc5)cnc4c3cc2CO1 nan
664182 20506 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 7 4.9 CC(C)c1nc2sc3c(SCC(=O)NCc4ccco4)ncnc3c2c2c1CCC2 nan
CHEMBL1307669 20506 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 7 4.9 CC(C)c1nc2sc3c(SCC(=O)NCc4ccco4)ncnc3c2c2c1CCC2 nan
2823681 20617 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 2 1 4.9 Cc1cc(C)c2[nH]c(C(=O)Nc3ccc(F)cc3Br)cc2c1 nan
CHEMBL1308537 20617 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 2 1 4.9 Cc1cc(C)c2[nH]c(C(=O)Nc3ccc(F)cc3Br)cc2c1 nan
135443911 20631 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 6 3.5 COc1ccc(N2CC(=O)C(c3nc(-c4ccccc4)cs3)=C2N)cc1 nan
CHEMBL1308652 20631 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 6 3.5 COc1ccc(N2CC(=O)C(c3nc(-c4ccccc4)cs3)=C2N)cc1 nan
7206305 20704 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 8 2.9 Cc1cc(NC(=O)CSc2ccc(-c3ccc4c(c3)OCO4)nn2)no1 nan
CHEMBL1309267 20704 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 8 2.9 Cc1cc(NC(=O)CSc2ccc(-c3ccc4c(c3)OCO4)nn2)no1 nan
546665 20830 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 5 3.0 CC(C)(C)S(=O)(=O)c1cnc(-c2ccc(Cl)cc2)nc1N nan
CHEMBL1310343 20830 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 5 3.0 CC(C)(C)S(=O)(=O)c1cnc(-c2ccc(Cl)cc2)nc1N nan
54693834 20915 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 3 2 5 2.9 CC1CCc2cc(F)cc3c(O)c(C(=O)NCc4ccco4)c(=O)n1c23 nan
CHEMBL1311072 20915 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 3 2 5 2.9 CC1CCc2cc(F)cc3c(O)c(C(=O)NCc4ccco4)c(=O)n1c23 nan
16746300 20938 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 618 8 0 8 6.1 COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CC(=O)N1CCN(c2ccccc2)CC1)c1ccc2c(c1)OCO2 nan
CHEMBL1311273 20938 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 618 8 0 8 6.1 COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CC(=O)N1CCN(c2ccccc2)CC1)c1ccc2c(c1)OCO2 nan
3413238 20940 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 2 7 2.8 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4ncsc4c3)sc2c1 nan
CHEMBL1311288 20940 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 2 7 2.8 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4ncsc4c3)sc2c1 nan
245201 20954 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 214 3 1 7 0.9 CNc1nc(SC)n(C)c(=O)c1N=O nan
CHEMBL1311401 20954 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 214 3 1 7 0.9 CNc1nc(SC)n(C)c(=O)c1N=O nan
16194626 21003 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 6 2.6 COc1ccc(N2CCN(C(c3cccs3)C(C)NS(C)(=O)=O)CC2)cc1 nan
CHEMBL1311746 21003 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 6 2.6 COc1ccc(N2CCN(C(c3cccs3)C(C)NS(C)(=O)=O)CC2)cc1 nan
3586870 21114 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 3 0 4 3.4 COc1ccc(Oc2cnc3ccccc3n2)cc1 nan
CHEMBL1312526 21114 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 3 0 4 3.4 COc1ccc(Oc2cnc3ccccc3n2)cc1 nan
645988 21143 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.3 O=C(CSc1nc2c(c(C(F)(F)F)n1)CCc1ccccc1-2)NCc1ccco1 nan
CHEMBL1312719 21143 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.3 O=C(CSc1nc2c(c(C(F)(F)F)n1)CCc1ccccc1-2)NCc1ccco1 nan
660699 21217 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 2 7 3.6 N#Cc1c(N)nc(SCC(=O)NCCc2ccccc2)c(C#N)c1-c1cccs1 nan
CHEMBL1313254 21217 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 2 7 3.6 N#Cc1c(N)nc(SCC(=O)NCCc2ccccc2)c(C#N)c1-c1cccs1 nan
6619041 21219 8 None -6 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 9 2 8 3.2 CCOc1ccc(NC(=O)CNC(=O)c2nn(-c3ccc(OC)c(OC)c3)c(=O)c3ccccc23)cc1 nan
CHEMBL1313270 21219 8 None -6 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 9 2 8 3.2 CCOc1ccc(NC(=O)CNC(=O)c2nn(-c3ccc(OC)c(OC)c3)c(=O)c3ccccc23)cc1 nan
2731590 21259 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 5 2.8 O=c1c2ccccc2[nH]c(=S)n1-c1ccc2c(c1)OCCO2 nan
CHEMBL1313595 21259 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 5 2.8 O=c1c2ccccc2[nH]c(=S)n1-c1ccc2c(c1)OCCO2 nan
11957277 21276 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 0 8 3.9 O=[N+]([O-])C(/C=C(\Cl)[N+](=O)[O-])=C1N(Cc2ccc(Cl)nc2)CCN1Cc1ccc(Cl)nc1 nan
CHEMBL1313693 21276 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 0 8 3.9 O=[N+]([O-])C(/C=C(\Cl)[N+](=O)[O-])=C1N(Cc2ccc(Cl)nc2)CCN1Cc1ccc(Cl)nc1 nan
16012576 21336 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 7 4.1 COc1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(OC)c1 nan
CHEMBL1314269 21336 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 7 4.1 COc1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(OC)c1 nan
16020367 21342 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 8 4.4 COC(=O)c1ccccc1NC(=O)c1cc2c(-c3ccc(OC)c(OC)c3)nn(C)c2s1 nan
CHEMBL1314309 21342 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 8 4.4 COC(=O)c1ccccc1NC(=O)c1cc2c(-c3ccc(OC)c(OC)c3)nn(C)c2s1 nan
16009631 21345 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 7 4.5 COc1ccc(C(=O)Nc2cccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)c2)cc1 nan
CHEMBL1314331 21345 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 7 4.5 COc1ccc(C(=O)Nc2cccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)c2)cc1 nan
16008545 21346 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 6 4.3 COc1ccc(C(=O)c2cn(Cc3cccc(C)c3)c3cc4c(cc3c2=O)OCO4)cc1 nan
CHEMBL1314337 21346 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 6 4.3 COc1ccc(C(=O)c2cn(Cc3cccc(C)c3)c3cc4c(cc3c2=O)OCO4)cc1 nan
16018962 21351 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.6 O=C(NCc1ccccc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1314402 21351 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.6 O=C(NCc1ccccc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16026094 21362 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 3.1 CC(C)c1ccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1 nan
CHEMBL1314533 21362 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 3.1 CC(C)c1ccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1 nan
2152595 21376 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 4 0 7 2.9 COC(=O)c1ccc2c(c1)s/c(=N/C(=O)c1ccc(S(=O)(=O)N3CCCCC3)cc1)n2C nan
CHEMBL1314815 21376 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 4 0 7 2.9 COC(=O)c1ccc2c(c1)s/c(=N/C(=O)c1ccc(S(=O)(=O)N3CCCCC3)cc1)n2C nan
135437061 21377 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3[nH]nc(C)c3c2=N)cc1Cl nan
CHEMBL1314816 21377 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3[nH]nc(C)c3c2=N)cc1Cl nan
16019424 21382 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 0 8 4.5 CC1CCCN(c2nc3c(S(=O)(=O)c4ccc(C(C)C)cc4)nnn3c3ccsc23)C1 nan
CHEMBL1314919 21382 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 0 8 4.5 CC1CCCN(c2nc3c(S(=O)(=O)c4ccc(C(C)C)cc4)nnn3c3ccsc23)C1 nan
16010115 21386 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 2.8 Cc1ccc(CNC(=O)C2CCN(c3nc4ccccc4n(C)c3=O)CC2)cc1 nan
CHEMBL1314966 21386 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 2.8 Cc1ccc(CNC(=O)C2CCN(c3nc4ccccc4n(C)c3=O)CC2)cc1 nan
16020210 21391 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 8 2 8 4.0 CCc1ccc(NC(=O)Cn2c(=O)n(-c3ccccc3)c(=O)c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc32)cc1 nan
CHEMBL1315042 21391 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 8 2 8 4.0 CCc1ccc(NC(=O)Cn2c(=O)n(-c3ccccc3)c(=O)c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc32)cc1 nan
16021834 21403 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 4 4.7 CSc1ncc(C(=O)Nc2c(C)cccc2C)c(-c2ccccc2)n1 nan
CHEMBL1315205 21403 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 4 4.7 CSc1ncc(C(=O)Nc2c(C)cccc2C)c(-c2ccccc2)n1 nan
3516704 21406 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 7 4.4 CCOCCCn1c(SCC(=O)NCc2ccccc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1315294 21406 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 7 4.4 CCOCCCn1c(SCC(=O)NCc2ccccc2)nc2c(sc3ccccc32)c1=O nan
16009766 21422 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 2 5 6.1 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c2cc3ccccc3o2)cc1 nan
CHEMBL1315409 21422 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 2 5 6.1 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c2cc3ccccc3o2)cc1 nan
16018863 21429 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 5 3.8 O=C(CCCn1c(=O)c2cccn2c2cccnc21)Nc1ccccc1Br nan
CHEMBL1315473 21429 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 5 3.8 O=C(CCCn1c(=O)c2cccn2c2cccnc21)Nc1ccccc1Br nan
16026940 21447 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 9 3.3 Cc1cccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)c1 nan
CHEMBL1315714 21447 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 9 3.3 Cc1cccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)c1 nan
2808363 21469 25 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 1 5 2.7 COC(=O)c1sccc1NC(=O)c1ccc(C#N)cc1 nan
CHEMBL1315955 21469 25 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 1 5 2.7 COC(=O)c1sccc1NC(=O)c1ccc(C#N)cc1 nan
16019191 21483 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 2 5.2 O=C(CCc1cn(Cc2ccc(F)cc2)c2ccccc12)NC1CCCCC1 nan
CHEMBL1316117 21483 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 2 5.2 O=C(CCc1cn(Cc2ccc(F)cc2)c2ccccc12)NC1CCCCC1 nan
16031991 21488 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 4.1 CCOC(=O)c1ccc(NC(=O)CSc2ccc(-c3sc(C)nc3C)nn2)cc1 nan
CHEMBL1316148 21488 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 4.1 CCOC(=O)c1ccc(NC(=O)CSc2ccc(-c3sc(C)nc3C)nn2)cc1 nan
2135282 21489 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 8 4.0 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(OC)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
CHEMBL1316149 21489 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 8 4.0 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(OC)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
16008335 21494 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 2 6 4.4 O=C(Nc1ccc(C(F)(F)F)cc1)C1CCC(CNS(=O)(=O)c2cccc3nsnc23)CC1 nan
CHEMBL1316232 21494 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 2 6 4.4 O=C(Nc1ccc(C(F)(F)F)cc1)C1CCC(CNS(=O)(=O)c2cccc3nsnc23)CC1 nan
16034305 21506 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 7 1 5 4.5 CC(C)CCNC(=O)c1cc(-c2cccnc2)nc2ccc(S(=O)(=O)N3CCC(C)CC3)cc12 nan
CHEMBL1316467 21506 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 7 1 5 4.5 CC(C)CCNC(=O)c1cc(-c2cccnc2)nc2ccc(S(=O)(=O)N3CCC(C)CC3)cc12 nan
3162808 21510 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 6 4.8 COc1ccc(C2CC(=O)c3cnc4c(-c5ccc(F)cc5)c(C)nn4c3C2)cc1OC nan
CHEMBL1316500 21510 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 6 4.8 COc1ccc(C2CC(=O)c3cnc4c(-c5ccc(F)cc5)c(C)nn4c3C2)cc1OC nan
3674872 21511 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 3.0 CCn1c(SCC(=O)Nc2ccccc2C(=O)OC)nc2ccsc2c1=O nan
CHEMBL1316511 21511 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 3.0 CCn1c(SCC(=O)Nc2ccccc2C(=O)OC)nc2ccsc2c1=O nan
7223037 21558 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 2 4 4.3 CCc1ccccc1NC(=O)C(=O)NCCc1sc(-c2cccc(C)c2)nc1C nan
CHEMBL1317197 21558 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 2 4 4.3 CCc1ccccc1NC(=O)C(=O)NCCc1sc(-c2cccc(C)c2)nc1C nan
16026110 21568 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 5 4.2 CC1=C(c2ccc(C(C)C)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 nan
CHEMBL1317332 21568 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 5 4.2 CC1=C(c2ccc(C(C)C)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 nan
7205418 21582 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1ccc(-n2ncc3c(NCc4ccccc4)ncnc32)cc1Cl nan
CHEMBL1317524 21582 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1ccc(-n2ncc3c(NCc4ccccc4)ncnc32)cc1Cl nan
16008313 21595 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 6 2 6 4.4 Cc1ccc(NC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)c(Cl)c1 nan
CHEMBL1317641 21595 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 6 2 6 4.4 Cc1ccc(NC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)c(Cl)c1 nan
16026429 21599 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 3 1 7 1.2 Cc1cc2c(cc1NS(=O)(=O)c1cccc(C#N)c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1317692 21599 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 3 1 7 1.2 Cc1cc2c(cc1NS(=O)(=O)c1cccc(C#N)c1)n(C)c(=O)c(=O)n2C nan
15989759 21611 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 5 3.3 Cc1ccc2nc(NCc3ccc(F)cc3)c3nncn3c2c1 nan
CHEMBL1317896 21611 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 5 3.3 Cc1ccc2nc(NCc3ccc(F)cc3)c3nncn3c2c1 nan
16016705 21628 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 4 2.6 O=C(CCC(=O)N1CCOc2ccccc21)NCc1cccs1 nan
CHEMBL1318069 21628 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 4 2.6 O=C(CCC(=O)N1CCOc2ccccc21)NCc1cccs1 nan
15988587 21635 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 6 1 6 4.5 O=C(Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2sc3ccccc3c21)NCc1ccccc1Cl nan
CHEMBL1318209 21635 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 6 1 6 4.5 O=C(Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2sc3ccccc3c21)NCc1ccccc1Cl nan
7245933 21639 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 0 6 3.4 CCOc1ccc(S(=O)(=O)c2cc3cccc(OCC)c3oc2=O)cc1 nan
CHEMBL1318269 21639 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 0 6 3.4 CCOc1ccc(S(=O)(=O)c2cc3cccc(OCC)c3oc2=O)cc1 nan
1164100 21677 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 0 6 3.4 COc1cccc(-c2nnc(SCC(=O)N3CCc4ccccc43)o2)c1 nan
CHEMBL1318572 21677 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 0 6 3.4 COc1cccc(-c2nnc(SCC(=O)N3CCc4ccccc43)o2)c1 nan
4077176 21687 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 3 5.6 CCC(C)NC(=O)c1cc(Sc2cccc(Cl)c2)nc2ccccc12 nan
CHEMBL1318673 21687 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 3 5.6 CCC(C)NC(=O)c1cc(Sc2cccc(Cl)c2)nc2ccccc12 nan
4055959 21712 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 3.6 Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C)c(C)c1 nan
CHEMBL1318877 21712 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 3.6 Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C)c(C)c1 nan
16022946 21789 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1319510 21789 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
2967498 21851 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 5 1 5 3.6 O=C(Nc1nccs1)c1ccc(COc2ccccc2)o1 nan
CHEMBL1320036 21851 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 5 1 5 3.6 O=C(Nc1nccs1)c1ccc(COc2ccccc2)o1 nan
5139336 21865 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 4.4 Cc1cccc2sc(NC(=O)c3ccc(OCC4CCCO4)cc3)nc12 nan
CHEMBL1320175 21865 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 4.4 Cc1cccc2sc(NC(=O)c3ccc(OCC4CCCO4)cc3)nc12 nan
16030546 21872 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 6 3.5 COc1ccccc1C(=O)Nc1cccc(OCc2cc(=O)n3ccccc3n2)c1 nan
CHEMBL1320207 21872 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 6 3.5 COc1ccccc1C(=O)Nc1cccc(OCc2cc(=O)n3ccccc3n2)c1 nan
16030772 21917 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.8 Cn1c(=O)c2c(SCC(=O)NCc3ccco3)nc(-c3ccccc3F)nc2n(C)c1=O nan
CHEMBL1320595 21917 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.8 Cn1c(=O)c2c(SCC(=O)NCc3ccco3)nc(-c3ccccc3F)nc2n(C)c1=O nan
16016685 21927 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 2 3 4.3 CCCCNC(=O)Nc1ccc2c(c1)N(C)C(=O)c1ccccc1S2 nan
CHEMBL1320647 21927 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 2 3 4.3 CCCCNC(=O)Nc1ccc2c(c1)N(C)C(=O)c1ccccc1S2 nan
16033946 21933 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 1 7 4.4 CCOC(=O)c1ccc(Nc2ncnc3c2cnn3-c2cccc(Cl)c2)cc1 nan
CHEMBL1320676 21933 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 1 7 4.4 CCOC(=O)c1ccc(Nc2ncnc3c2cnn3-c2cccc(Cl)c2)cc1 nan
944701 21939 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 4 1 6 2.9 COc1ccc2nc(O)c(COC(=O)c3ccco3)cc2c1 nan
CHEMBL1320788 21939 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 4 1 6 2.9 COc1ccc2nc(O)c(COC(=O)c3ccco3)cc2c1 nan
5135847 21971 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 2 4 3.8 CCOC(=O)c1cc2c(nc1N=C(S)NCc1ccccc1)CCCC2 nan
CHEMBL1321064 21971 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 2 4 3.8 CCOC(=O)c1cc2c(nc1N=C(S)NCc1ccccc1)CCCC2 nan
3634798 21974 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 0 7 4.5 CCOC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1CCc1ccccc1 nan
CHEMBL1321100 21974 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 0 7 4.5 CCOC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1CCc1ccccc1 nan
6473515 21990 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 2 5 3.1 COc1ccc(S(=O)(=O)Nc2ccccn2)cc1C(=O)Nc1ccccc1 nan
CHEMBL1321208 21990 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 2 5 3.1 COc1ccc(S(=O)(=O)Nc2ccccn2)cc1C(=O)Nc1ccccc1 nan
16026080 22025 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 7 2.6 CCc1ccccc1NC(=O)c1cnc2sc(N3CCCC3)nn2c1=O nan
CHEMBL1321609 22025 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 7 2.6 CCc1ccccc1NC(=O)c1cnc2sc(N3CCCC3)nn2c1=O nan
661514 22030 9 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 8 2.7 COc1ccc(-c2nnc3sc(CN4C(=O)c5ccccc5C4=O)nn23)cc1 nan
CHEMBL1321633 22030 9 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 8 2.7 COc1ccc(-c2nnc3sc(CN4C(=O)c5ccccc5C4=O)nn23)cc1 nan
963196 22068 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 5 1 3 4.5 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)c(C)c1 nan
CHEMBL1321920 22068 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 5 1 3 4.5 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)c(C)c1 nan
1034156 22071 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 2 4 2.9 Cc1cc2oc(C(=O)NCc3ccc(S(N)(=O)=O)cc3)c(C)c2cc1C nan
CHEMBL1321976 22071 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 2 4 2.9 Cc1cc2oc(C(=O)NCc3ccc(S(N)(=O)=O)cc3)c(C)c2cc1C nan
16026098 22072 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 1 5 3.7 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 nan
CHEMBL1321983 22072 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 1 5 3.7 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 nan
1480476 22125 24 None -12 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CC(C)Nc1nc(-c2ccncc2)nc(-c2ccc(Cl)cc2)c1C#N nan
CHEMBL1322430 22125 24 None -12 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CC(C)Nc1nc(-c2ccncc2)nc(-c2ccc(Cl)cc2)c1C#N nan
16021832 22243 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 4 4.7 CSc1ncc(C(=O)Nc2cccc(C)c2C)c(-c2ccccc2)n1 nan
CHEMBL1323559 22243 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 4 4.7 CSc1ncc(C(=O)Nc2cccc(C)c2C)c(-c2ccccc2)n1 nan
4868391 22290 34 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 3 4.5 Sc1ncc(-c2ccc(Cl)cc2)n1Cc1ccccc1 nan
CHEMBL1323909 22290 34 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 3 4.5 Sc1ncc(-c2ccc(Cl)cc2)n1Cc1ccccc1 nan
7284118 22294 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 9 1 5 3.2 CCOc1ccc(CCNC(=O)Cn2ccc3ccccc3c2=O)cc1OCC nan
CHEMBL1323924 22294 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 9 1 5 3.2 CCOc1ccc(CCNC(=O)Cn2ccc3ccccc3c2=O)cc1OCC nan
2135896 22312 6 None -158 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 7 2 7 2.4 COc1ccc(OC)c(NC(=O)c2nnn(CCc3ccccc3)c2N)c1 nan
CHEMBL1324085 22312 6 None -158 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 7 2 7 2.4 COc1ccc(OC)c(NC(=O)c2nnn(CCc3ccccc3)c2N)c1 nan
3422137 22317 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 8 0 9 2.0 COCCn1c(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1324117 22317 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 8 0 9 2.0 COCCn1c(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
16015664 22367 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 7 1 6 6.6 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccc(Cl)cc3)on2)cc1 nan
CHEMBL1324545 22367 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 7 1 6 6.6 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccc(Cl)cc3)on2)cc1 nan
5299986 22410 23 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 4 1 5 5.1 N#Cc1cc2c(nc1SCC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C1CCN2CC1 nan
CHEMBL1324899 22410 23 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 4 1 5 5.1 N#Cc1cc2c(nc1SCC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C1CCN2CC1 nan
2967360 22431 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 4 5.3 Cc1ccc(N(Cc2cc3ccc(C)cc3nc2O)S(=O)(=O)c2ccccc2)c(C)c1 nan
CHEMBL1325059 22431 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 4 5.3 Cc1ccc(N(Cc2cc3ccc(C)cc3nc2O)S(=O)(=O)c2ccccc2)c(C)c1 nan
4013085 22449 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 7 2.7 CCOC(=O)c1ccc(NC2Nc3cc(C)nn3S2)cc1 nan
CHEMBL1325232 22449 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 7 2.7 CCOC(=O)c1ccc(NC2Nc3cc(C)nn3S2)cc1 nan
4877095 22467 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 1 6 4.1 CCOC(=O)c1sc(NC(=O)c2cc3c(s2)CCC(C)C3)nc1C nan
CHEMBL1325413 22467 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 1 6 4.1 CCOC(=O)c1sc(NC(=O)c2cc3c(s2)CCC(C)C3)nc1C nan
16012280 22477 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 1.7 Cc1cccc(C)c1NC(=O)CCS(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1325535 22477 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 1.7 Cc1cccc(C)c1NC(=O)CCS(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
16011188 22490 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.4 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(C)cc1C nan
CHEMBL1325716 22490 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.4 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(C)cc1C nan
709602 22498 5 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 2 5 3.6 Cc1c(NC(=O)c2nc[nH]n2)cccc1-c1nc2ccccc2s1 nan
CHEMBL1325780 22498 5 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 2 5 3.6 Cc1c(NC(=O)c2nc[nH]n2)cccc1-c1nc2ccccc2s1 nan
3619431 22561 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 0 4 5.7 O=C(c1cccs1)c1cn(CCOc2ccc(Cl)cc2)c2ccccc12 nan
CHEMBL1326440 22561 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 0 4 5.7 O=C(c1cccs1)c1cn(CCOc2ccc(Cl)cc2)c2ccccc12 nan
663870 22568 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.6 Cc1ccc(C(=O)OCc2cc3ccccc3nc2O)cc1 nan
CHEMBL1326511 22568 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.6 Cc1ccc(C(=O)OCc2cc3ccccc3nc2O)cc1 nan
16018929 22578 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 11 1 7 3.6 CCOc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)cc1OCC nan
CHEMBL1326604 22578 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 11 1 7 3.6 CCOc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)cc1OCC nan
17583882 22587 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 1 5 3.5 CCCCc1cc(=O)oc2cc(OCC(=O)Nc3ccccn3)ccc12 nan
CHEMBL1326654 22587 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 1 5 3.5 CCCCc1cc(=O)oc2cc(OCC(=O)Nc3ccccn3)ccc12 nan
1477181 22631 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 6 3.7 CC(=O)c1cc(C#N)c(NCc2cc(-c3ccccc3)no2)nc1C nan
CHEMBL1327040 22631 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 6 3.7 CC(=O)c1cc(C#N)c(NCc2cc(-c3ccccc3)no2)nc1C nan
16034758 22639 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.6 COc1ccc(NC(=O)c2sc3nc[nH]c(=O)c3c2C)cc1OC nan
CHEMBL1327116 22639 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.6 COc1ccc(NC(=O)c2sc3nc[nH]c(=O)c3c2C)cc1OC nan
16008896 22647 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 5 3.0 COc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)cc1 nan
CHEMBL1327173 22647 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 5 3.0 COc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)cc1 nan
4227789 22678 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 6 0 5 5.5 CCN(CC)C(=O)C1CCCN(c2ncnc3c2c(-c2ccccc2)cn3-c2cccc(C)c2)C1 nan
CHEMBL1327499 22678 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 6 0 5 5.5 CCN(CC)C(=O)C1CCCN(c2ncnc3c2c(-c2ccccc2)cn3-c2cccc(C)c2)C1 nan
16032611 22783 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 2 3 2.9 O=C(NC1CC(=O)N(c2ccc(Cl)cc2)C1)C(=O)c1c[nH]c2ccccc12 nan
CHEMBL1328167 22783 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 2 3 2.9 O=C(NC1CC(=O)N(c2ccc(Cl)cc2)C1)C(=O)c1c[nH]c2ccccc12 nan
1426216 22853 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 2 8 4.1 Cc1cc(=O)n2c(C(=O)Nc3ccc(C(=O)OC(C)C)cc3)c(C(=O)Nc3ccccc3)sc2n1 nan
CHEMBL1328860 22853 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 2 8 4.1 Cc1cc(=O)n2c(C(=O)Nc3ccc(C(=O)OC(C)C)cc3)c(C(=O)Nc3ccccc3)sc2n1 nan
857007 22854 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 5 1 4 4.2 Cc1cc2cc(C)c(SCC(=O)NCc3ccco3)nc2cc1C nan
CHEMBL1328861 22854 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 5 1 4 4.2 Cc1cc2cc(C)c(SCC(=O)NCc3ccco3)nc2cc1C nan
16015065 22867 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 6 5.3 CC(=O)c1cccc(NC(=O)c2sc(-n3nc(C)c(CCC(C)C)c3C)nc2C)c1 nan
CHEMBL1328989 22867 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 6 5.3 CC(=O)c1cccc(NC(=O)c2sc(-n3nc(C)c(CCC(C)C)c3C)nc2C)c1 nan
7294635 22894 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 4 4.7 Nc1c(C(=O)Nc2ccccc2Cl)c2ccccn2c1C(=O)c1ccccc1 nan
CHEMBL1329216 22894 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 4 4.7 Nc1c(C(=O)Nc2ccccc2Cl)c2ccccn2c1C(=O)c1ccccc1 nan
2986428 22925 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 8 4.0 CC(C)CNc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CC(C)(C)OC3 nan
CHEMBL1329460 22925 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 8 4.0 CC(C)CNc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CC(C)(C)OC3 nan
7422802 22929 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 2.8 Cc1ccc(Cn2cccc(C(=O)Nc3cc(C)on3)c2=O)cc1 nan
CHEMBL1329510 22929 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 2.8 Cc1ccc(Cn2cccc(C(=O)Nc3cc(C)on3)c2=O)cc1 nan
7889414 22975 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 10 1.5 CCCn1c(N)c(C(=O)CSc2ncnc3sccc23)c(=O)n(C)c1=O nan
CHEMBL1329885 22975 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 10 1.5 CCCn1c(N)c(C(=O)CSc2ncnc3sccc23)c(=O)n(C)c1=O nan
1038210 22985 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 6 0 8 2.7 CCOC(=O)CCSc1nc(N2CCOCC2)c2c(c1C#N)CC(C)(C)OC2 nan
CHEMBL1329993 22985 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 6 0 8 2.7 CCOC(=O)CCSc1nc(N2CCOCC2)c2c(c1C#N)CC(C)(C)OC2 nan
16009180 23032 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCO4)c3ccc(OC)cc3c2=O)cc1 nan
CHEMBL1330381 23032 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCO4)c3ccc(OC)cc3c2=O)cc1 nan
1510063 23046 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 4 3.4 CCC(=O)c1cc2c(cc1NC(=O)c1ccccc1F)OCCO2 nan
CHEMBL1330472 23046 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 4 3.4 CCC(=O)c1cc2c(cc1NC(=O)c1ccccc1F)OCCO2 nan
16019798 23081 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 2 6 2.6 COc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)C2)cc1OC nan
CHEMBL1330797 23081 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 2 6 2.6 COc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)C2)cc1OC nan
1078194 23130 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 2 5 3.5 Cc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)cc1C nan
CHEMBL1331082 23130 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 2 5 3.5 Cc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)cc1C nan
1367422 23132 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 6 3.6 O=C(NC(=S)Nc1cccc(-c2nc3ncccc3o2)c1)c1ccco1 nan
CHEMBL1331090 23132 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 6 3.6 O=C(NC(=S)Nc1cccc(-c2nc3ncccc3o2)c1)c1ccco1 nan
15990786 23155 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 13 2 5 6.4 CCCCN(CCCNC(=O)c1cc(Nc2ccc(OC)cc2)nc2ccccc12)Cc1ccccc1 nan
CHEMBL1331246 23155 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 13 2 5 6.4 CCCCN(CCCNC(=O)c1cc(Nc2ccc(OC)cc2)nc2ccccc12)Cc1ccccc1 nan
1426224 23163 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 2 6 4.1 CCc1ccc(NC(=O)c2c(C(=O)Nc3ccccc3)sc3nc(C)cc(=O)n23)cc1 nan
CHEMBL1331302 23163 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 2 6 4.1 CCc1ccc(NC(=O)c2c(C(=O)Nc3ccccc3)sc3nc(C)cc(=O)n23)cc1 nan
16009858 23192 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 9 2 6 5.7 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3OC)oc3ccccc23)cc1OCC nan
CHEMBL1331538 23192 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 9 2 6 5.7 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3OC)oc3ccccc23)cc1OCC nan
965763 23225 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 4 3.8 Cc1cc(OCC(=O)Nc2ccc3oc(=O)ccc3c2)ccc1Cl nan
CHEMBL1331830 23225 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 4 3.8 Cc1cc(OCC(=O)Nc2ccc3oc(=O)ccc3c2)ccc1Cl nan
4216258 23261 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 3 6 6.0 CCOc1ccccc1Nc1sc(C(=O)c2ccccc2)c(N)c1C(=O)Nc1ccccc1 nan
CHEMBL1332095 23261 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 3 6 6.0 CCOc1ccccc1Nc1sc(C(=O)c2ccccc2)c(N)c1C(=O)Nc1ccccc1 nan
2670204 23272 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 0 9 1.7 COc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)c(OC)c1 nan
CHEMBL1332216 23272 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 0 9 1.7 COc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)c(OC)c1 nan
2151601 23291 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 5.5 Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1332323 23291 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 5.5 Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 nan
16012517 23295 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 2 5 6.3 CCOc1ccc(-c2cc(NC(=O)Nc3ccccc3C(F)(F)F)c(C(=O)OC)s2)cc1 nan
CHEMBL1332340 23295 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 2 5 6.3 CCOc1ccc(-c2cc(NC(=O)Nc3ccccc3C(F)(F)F)c(C(=O)OC)s2)cc1 nan
2243529 23296 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 0 3 3.7 O=C(c1cccs1)N1C(=O)c2cccc3cccc1c23 nan
CHEMBL1332342 23296 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 0 3 3.7 O=C(c1cccs1)N1C(=O)c2cccc3cccc1c23 nan
867009 23413 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 2 3 3.7 COc1ccc(Cl)cc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C nan
CHEMBL1333261 23413 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 2 3 3.7 COc1ccc(Cl)cc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C nan
677173 23440 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 2 4 3.5 CCCc1nnc(N=C(S)Nc2ccccc2)s1 nan
CHEMBL1333504 23440 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 2 4 3.5 CCCc1nnc(N=C(S)Nc2ccccc2)s1 nan
3623159 23474 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 7 1 4 5.3 CCOc1ccc(Sc2cc(C(=O)NC(C)CC)c3ccccc3n2)cc1 nan
CHEMBL1333744 23474 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 7 1 4 5.3 CCOc1ccc(Sc2cc(C(=O)NC(C)CC)c3ccccc3n2)cc1 nan
16008956 23512 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 7 1 6 4.2 CCn1c(=O)c2cc(C(=O)NCCc3ccc(OC)c(OC)c3)sc2c2ccccc21 nan
CHEMBL1334014 23512 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 7 1 6 4.2 CCn1c(=O)c2cc(C(=O)NCCc3ccc(OC)c(OC)c3)sc2c2ccccc21 nan
2196864 23557 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 4.2 CCn1c(Cc2ccccc2)nnc1SCC(=O)Nc1nc2ccccc2s1 nan
CHEMBL1334332 23557 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 4.2 CCn1c(Cc2ccccc2)nnc1SCC(=O)Nc1nc2ccccc2s1 nan
3622707 23631 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 4 5.1 Cc1nc(SCc2cccc(F)c2)c2oc3ccccc3c2n1 nan
CHEMBL1335007 23631 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 4 5.1 Cc1nc(SCc2cccc(F)c2)c2oc3ccccc3c2n1 nan
16008370 23657 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 1 4 3.7 Cn1c(=O)cc(SCC(=O)NCc2ccc(F)cc2)c2cc(Cl)ccc21 nan
CHEMBL1335160 23657 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 1 4 3.7 Cn1c(=O)cc(SCC(=O)NCc2ccc(F)cc2)c2cc(Cl)ccc21 nan
16020489 23696 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 0 5 3.7 CCN(CC)c1cc2c(cc1F)c(=O)c(S(=O)(=O)c1cccc(C)c1)cn2C nan
CHEMBL1335441 23696 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 0 5 3.7 CCN(CC)c1cc2c(cc1F)c(=O)c(S(=O)(=O)c1cccc(C)c1)cn2C nan
16012518 23700 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 5 5.3 CCOc1ccccc1NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccccc2)c1C nan
CHEMBL1335479 23700 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 5 5.3 CCOc1ccccc1NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccccc2)c1C nan
16018933 23707 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 1 7 2.8 COc1ccc(OC)c(CCNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)c1 nan
CHEMBL1335514 23707 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 1 7 2.8 COc1ccc(OC)c(CCNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)c1 nan
16022436 23718 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 2 7 5.2 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3nc2s1 nan
CHEMBL1335596 23718 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 2 7 5.2 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3nc2s1 nan
3221114 23758 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 6 1 6 3.3 COCCN=C(S)N(Cc1cc2cc(C)ccc2n2nnnc12)C1CCCC1 nan
CHEMBL1335947 23758 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 6 1 6 3.3 COCCN=C(S)N(Cc1cc2cc(C)ccc2n2nnnc12)C1CCCC1 nan
16015039 23775 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 5.4 CCc1ccccc1NC(=O)c1sc(-n2nc(C)c(Cc3ccc4c(c3)OCO4)c2C)nc1C nan
CHEMBL1336092 23775 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 5.4 CCc1ccccc1NC(=O)c1sc(-n2nc(C)c(Cc3ccc4c(c3)OCO4)c2C)nc1C nan
2138945 23799 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 5 3.5 O=C(Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1)c1ccc(F)cc1 nan
CHEMBL1336262 23799 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 5 3.5 O=C(Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1)c1ccc(F)cc1 nan
6220215 23856 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 3 3.2 CC1=CC2=NC(=O)/C(=C\c3c(C)[nH]c4ccc(C)cc34)C(=N)N2O1 nan
CHEMBL1336784 23856 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 3 3.2 CC1=CC2=NC(=O)/C(=C\c3c(C)[nH]c4ccc(C)cc34)C(=N)N2O1 nan
16026936 23893 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 0 9 3.0 O=C(COc1ccccc1)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
CHEMBL1337126 23893 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 0 9 3.0 O=C(COc1ccccc1)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
1486592 23945 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 4 1 7 1.7 COc1ccc(Nc2nc(N(C)C)oc(=O)c2C#N)cc1 nan
CHEMBL1337568 23945 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 4 1 7 1.7 COc1ccc(Nc2nc(N(C)C)oc(=O)c2C#N)cc1 nan
1485789 23966 23 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 2 4.3 O=C(c1ccc(F)cc1)c1ccc(-c2ccc(F)cc2)nc1 nan
CHEMBL1337770 23966 23 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 2 4.3 O=C(c1ccc(F)cc1)c1ccc(-c2ccc(F)cc2)nc1 nan
16033861 24000 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 2 8 4.6 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4cccs4)cc3nc2s1 nan
CHEMBL1338096 24000 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 2 8 4.6 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4cccs4)cc3nc2s1 nan
1265732 24052 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 4 5.4 O=C(Cn1c(S)nc(-c2ccccc2)c1-c1ccccc1)c1ccccc1 nan
CHEMBL1338427 24052 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 4 5.4 O=C(Cn1c(S)nc(-c2ccccc2)c1-c1ccccc1)c1ccccc1 nan
16026086 24109 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 7 2.3 Cc1ccccc1NC(=O)c1cnc2sc(N3CCCC3)nn2c1=O nan
CHEMBL1339014 24109 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 7 2.3 Cc1ccccc1NC(=O)c1cnc2sc(N3CCCC3)nn2c1=O nan
15944700 24318 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 2 5 4.4 O=C(Nc1cc(Cl)cc(Cl)c1)c1ccc(Cn2c(=O)[nH]c3ccsc3c2=O)cc1 nan
CHEMBL1340950 24318 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 2 5 4.4 O=C(Nc1cc(Cl)cc(Cl)c1)c1ccc(Cn2c(=O)[nH]c3ccsc3c2=O)cc1 nan
5069163 24333 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 2 7 2.9 COc1ccc(CNC(=O)CCCn2c(=S)[nH]c3cc4c(cc3c2=O)OCO4)cc1 nan
CHEMBL1341068 24333 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 2 7 2.9 COc1ccc(CNC(=O)CCCn2c(=S)[nH]c3cc4c(cc3c2=O)OCO4)cc1 nan
855559 24456 2 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 3.5 CCN(C(=O)c1ccco1)c1nnc(-c2ccc(OC)cc2)s1 nan
CHEMBL1342076 24456 2 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 3.5 CCN(C(=O)c1ccco1)c1nnc(-c2ccc(OC)cc2)s1 nan
3149126 24470 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 10 2 7 3.5 CCOCCCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2ccccc2c1=O nan
CHEMBL1342207 24470 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 10 2 7 3.5 CCOCCCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2ccccc2c1=O nan
1086862 24489 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 7 3.4 COc1ccc(C(=O)Nc2nnc(Cc3ccc(OC)c(OC)c3)s2)cc1 nan
CHEMBL1342348 24489 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 7 3.4 COc1ccc(C(=O)Nc2nnc(Cc3ccc(OC)c(OC)c3)s2)cc1 nan
5443591 24528 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 8 1 6 3.8 CCOC(=O)/C(C#N)=C\c1ccc(OCC(=O)Nc2ccc(C)cc2C)c(OC)c1 nan
CHEMBL1342661 24528 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 8 1 6 3.8 CCOC(=O)/C(C#N)=C\c1ccc(OCC(=O)Nc2ccc(C)cc2C)c(OC)c1 nan
665611 24565 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 1 6 3.9 Cc1cc(-c2nnc3sc(-c4ccc(Cl)cc4Cl)nn23)[nH]n1 nan
CHEMBL1342889 24565 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 1 6 3.9 Cc1cc(-c2nnc3sc(-c4ccc(Cl)cc4Cl)nn23)[nH]n1 nan
5063932 24623 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 2 5 3.6 O=C(NCc1ccco1)c1ccc2c(=O)n(-c3ccccc3)c(=S)[nH]c2c1 nan
CHEMBL1343363 24623 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 2 5 3.6 O=C(NCc1ccco1)c1ccc2c(=O)n(-c3ccccc3)c(=S)[nH]c2c1 nan
2452051 24772 4 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 8 4.6 N#Cc1ccc(CSc2nnc(NC(=O)c3ccc4ncsc4c3)s2)cc1 nan
CHEMBL1344739 24772 4 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 8 4.6 N#Cc1ccc(CSc2nnc(NC(=O)c3ccc4ncsc4c3)s2)cc1 nan
2335388 24860 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 2 1 5 3.0 Cc1ccnc(NC(=O)c2ccc3c(c2)S(=O)(=O)c2ccccc2C3=O)c1 nan
CHEMBL1345474 24860 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 2 1 5 3.0 Cc1ccnc(NC(=O)c2ccc3c(c2)S(=O)(=O)c2ccccc2C3=O)c1 nan
666154 24861 9 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 6 4.2 Cc1ccc(-n2nc(C)c3c(-c4cccs4)c(C#N)c(N)nc32)cc1 nan
CHEMBL1345487 24861 9 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 6 4.2 Cc1ccc(-n2nc(C)c3c(-c4cccs4)c(C#N)c(N)nc32)cc1 nan
2040126 24866 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 2 6 2.6 Cc1ccc(/C=C2\SC(=S)N(CCC(=O)NNS(=O)(=O)c3ccccc3)C2=O)cc1 nan
CHEMBL1345551 24866 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 2 6 2.6 Cc1ccc(/C=C2\SC(=S)N(CCC(=O)NNS(=O)(=O)c3ccccc3)C2=O)cc1 nan
3185713 24939 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 10 3 8 3.1 CCc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NCC1CCCO1)c1ccc(N(C)C)cc1 nan
CHEMBL1346198 24939 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 10 3 8 3.1 CCc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NCC1CCCO1)c1ccc(N(C)C)cc1 nan
1409877 25001 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 2.8 Cc1cccc(NC(=O)COC(=O)c2ccc3c(c2)OCO3)c1C nan
CHEMBL1346710 25001 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 2.8 Cc1cccc(NC(=O)COC(=O)c2ccc3c(c2)OCO3)c1C nan
3846689 25019 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 6 2.4 COCc1nc2oc3ccc(F)cc3c(=O)c2cc1C(=O)OC nan
CHEMBL1346831 25019 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 6 2.4 COCc1nc2oc3ccc(F)cc3c(=O)c2cc1C(=O)OC nan
2813569 25068 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 6 3.3 O=C(COc1ncnc2cc(Cl)ccc12)c1ccc2c(c1)OCCO2 nan
CHEMBL1347186 25068 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 6 3.3 O=C(COc1ncnc2cc(Cl)ccc12)c1ccc2c(c1)OCCO2 nan
2426514 25129 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 1 0 5 2.6 Cc1cc(=O)n2nc(-c3ccccc3)sc2c1C#N nan
CHEMBL1347674 25129 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 1 0 5 2.6 Cc1cc(=O)n2nc(-c3ccccc3)sc2c1C#N nan
2950848 25202 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 6 1 5 3.2 COCc1cc(C)nc(SCC(=O)NC2CCCCC2C)c1C#N nan
CHEMBL1348333 25202 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 6 1 5 3.2 COCc1cc(C)nc(SCC(=O)NC2CCCCC2C)c1C#N nan
664720 25247 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 7 5.4 CC(C)c1nc2sc3c(NCc4ccco4)ncnc3c2c2c1COC(C)(C)C2 nan
CHEMBL1348840 25247 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 7 5.4 CC(C)c1nc2sc3c(NCc4ccco4)ncnc3c2c2c1COC(C)(C)C2 nan
780682 25352 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 3 3.8 C=CCn1c(NC(=O)c2ccc(C)cc2)nc2ccccc21 nan
CHEMBL1349635 25352 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 3 3.8 C=CCn1c(NC(=O)c2ccc(C)cc2)nc2ccccc21 nan
7157934 25463 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 1.6 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc(S(=O)(=O)N2CCCC2)cc1 nan
CHEMBL1350603 25463 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 1.6 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc(S(=O)(=O)N2CCCC2)cc1 nan
16194401 25564 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 2 6 2.8 CCOC(=O)N1CCC(NC(=O)c2cc3c(O)nc4ccccc4c3n2C)CC1 nan
CHEMBL1351462 25564 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 2 6 2.8 CCOC(=O)N1CCC(NC(=O)c2cc3c(O)nc4ccccc4c3n2C)CC1 nan
1433829 25696 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 5 1 5 2.5 COc1ccc2nc(SCC(=O)NC3CC3)c(C#N)cc2c1 nan
CHEMBL1352517 25696 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 5 1 5 2.5 COc1ccc2nc(SCC(=O)NC3CC3)c(C#N)cc2c1 nan
5112429 25729 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 2 7 1.9 N#CCC(=O)NNc1c([N+](=O)[O-])cc(C(F)(F)F)cc1[N+](=O)[O-] nan
CHEMBL1352781 25729 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 2 7 1.9 N#CCC(=O)NNc1c([N+](=O)[O-])cc(C(F)(F)F)cc1[N+](=O)[O-] nan
4850085 25760 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 2 8 2.8 CCOC(=O)c1sc2nc(C)nc(NCCc3ccc(S(N)(=O)=O)cc3)c2c1C nan
CHEMBL1353043 25760 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 2 8 2.8 CCOC(=O)c1sc2nc(C)nc(NCCc3ccc(S(N)(=O)=O)cc3)c2c1C nan
3350830 25903 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 2 4 4.7 Cc1cc(C)c(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)c(Cl)c1 nan
CHEMBL1354025 25903 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 2 4 4.7 Cc1cc(C)c(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)c(Cl)c1 nan
16017542 25946 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 7 3.6 CCN(c1ccc(C)cc1C)S(=O)(=O)c1nnc(NC(=O)c2ccccc2OC)s1 nan
CHEMBL1354338 25946 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 7 3.6 CCN(c1ccc(C)cc1C)S(=O)(=O)c1nnc(NC(=O)c2ccccc2OC)s1 nan
3415736 25960 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 2 6 2.3 COc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(S(=O)(=O)N4CCCC4)cc23)c(OC)c1 nan
CHEMBL1354486 25960 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 2 6 2.3 COc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(S(=O)(=O)N4CCCC4)cc23)c(OC)c1 nan
16008465 25967 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 4 4.5 Cc1nc2cc(-c3cccc(F)c3)nn2c(C)c1CCC(=O)NC1CCCCC1 nan
CHEMBL1354574 25967 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 4 4.5 Cc1nc2cc(-c3cccc(F)c3)nn2c(C)c1CCC(=O)NC1CCCCC1 nan
16008364 25968 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 1 4 5.0 Cc1ccc(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)c(Br)c1 nan
CHEMBL1354597 25968 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 1 4 5.0 Cc1ccc(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)c(Br)c1 nan
16034362 25970 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 9 1 9 2.1 CSCCC(NS(=O)(=O)c1ccc2c(c1)oc(=O)n2C)C(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
CHEMBL1354617 25970 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 9 1 9 2.1 CSCCC(NS(=O)(=O)c1ccc2c(c1)oc(=O)n2C)C(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
16029590 25975 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 1 3 5.8 O=C(Nc1ccc(Br)cc1F)c1ccc2nc(CCc3ccccc3)oc2c1 nan
CHEMBL1354702 25975 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 1 3 5.8 O=C(Nc1ccc(Br)cc1F)c1ccc2nc(CCc3ccccc3)oc2c1 nan
16024765 25980 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 3 1 4 3.8 O=C(Cn1c(=O)c(C(F)(F)F)nc2ccccc21)Nc1cccc(Br)c1 nan
CHEMBL1354803 25980 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 3 1 4 3.8 O=C(Cn1c(=O)c(C(F)(F)F)nc2ccccc21)Nc1cccc(Br)c1 nan
16026345 25986 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 5 2.6 Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)NC(C)C)c32)cc1 nan
CHEMBL1354863 25986 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 5 2.6 Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)NC(C)C)c32)cc1 nan
7872437 25988 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 3 6 3.8 CC(=O)Nc1ccc(NC(=O)CCc2nc(O)c3c4c(sc3n2)CCCC4)cc1 nan
CHEMBL1354869 25988 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 3 6 3.8 CC(=O)Nc1ccc(NC(=O)CCc2nc(O)c3c4c(sc3n2)CCCC4)cc1 nan
2135022 25998 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.3 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(C)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
CHEMBL1354981 25998 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.3 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(C)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
135416424 26001 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 3 2 6 4.8 Cc1ccc2oc(-c3cc(NC(=O)c4ccc5c(c4)OCCO5)cc(C)c3O)nc2c1 nan
CHEMBL1355004 26001 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 3 2 6 4.8 Cc1ccc2oc(-c3cc(NC(=O)c4ccc5c(c4)OCCO5)cc(C)c3O)nc2c1 nan
16019041 26020 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 8 1 6 3.2 CC(C)OCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1355237 26020 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 8 1 6 3.2 CC(C)OCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
135437043 26030 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 3 7 3.3 CCOc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3[nH]nc(C)c3c2=N)cc1 nan
CHEMBL1355309 26030 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 3 7 3.3 CCOc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3[nH]nc(C)c3c2=N)cc1 nan
16011751 26035 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 2 7 3.3 CCOC(=O)c1ccc(NC(=O)CC(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1 nan
CHEMBL1355424 26035 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 2 7 3.3 CCOC(=O)c1ccc(NC(=O)CC(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1 nan
16027630 26038 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1ccccc1OCC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1355500 26038 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1ccccc1OCC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3ccsc3n2)cc1 nan
16025481 26043 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 3.4 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(C)S3(=O)=O)cc1 nan
CHEMBL1355611 26043 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 3.4 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(C)S3(=O)=O)cc1 nan
16020103 26051 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 7 4.2 CCOc1ccc(CNC(=O)c2nn(-c3ccc(OC)cc3)c(=O)c3c2c2ccccc2n3C)cc1 nan
CHEMBL1355692 26051 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 7 4.2 CCOc1ccc(CNC(=O)c2nn(-c3ccc(OC)cc3)c(=O)c3c2c2ccccc2n3C)cc1 nan
16026942 26057 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 9 3.3 Cc1ccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)cc1 nan
CHEMBL1355764 26057 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 9 3.3 Cc1ccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)cc1 nan
16011703 26061 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 7 3.6 COc1ccc(CCNc2nc3ccc(Cl)cc3n3cnnc23)cc1OC nan
CHEMBL1355798 26061 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 7 3.6 COc1ccc(CCNc2nc3ccc(Cl)cc3n3cnnc23)cc1OC nan
16026082 26062 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 7 2.6 CCc1ccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1 nan
CHEMBL1355799 26062 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 7 2.6 CCc1ccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1 nan
16027128 26089 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 3 0 4 4.6 Cc1cc(=O)n(Cc2cccc(Br)c2)c2c1c(C)nn2-c1ccccc1 nan
CHEMBL1356158 26089 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 3 0 4 4.6 Cc1cc(=O)n(Cc2cccc(Br)c2)c2c1c(C)nn2-c1ccccc1 nan
16020942 26097 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 3 5.4 CC(NC(=O)Cn1c(-c2cccs2)cc2cc(F)ccc21)c1ccccc1 nan
CHEMBL1356228 26097 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 3 5.4 CC(NC(=O)Cn1c(-c2cccs2)cc2cc(F)ccc21)c1ccccc1 nan
2869380 26114 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 2 3 5.9 O=C(Nc1sc2c(c1C(=O)Nc1ccccc1Cl)CCCC2)c1ccccc1F nan
CHEMBL1356452 26114 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 2 3 5.9 O=C(Nc1sc2c(c1C(=O)Nc1ccccc1Cl)CCCC2)c1ccccc1F nan
4802695 26120 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 3 5 2.2 O=C(COC(=O)c1cc(Cl)ccc1O)NC(=O)NCc1ccccc1 nan
CHEMBL1356574 26120 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 3 5 2.2 O=C(COC(=O)c1cc(Cl)ccc1O)NC(=O)NCc1ccccc1 nan
16015066 26127 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 4 4.8 Cc1nc(SCC(=O)Nc2ccccc2Cl)cc(-c2ccccc2)n1 nan
CHEMBL1356682 26127 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 4 4.8 Cc1nc(SCC(=O)Nc2ccccc2Cl)cc(-c2ccccc2)n1 nan
16018801 26141 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 2 7 1.0 NS(=O)(=O)c1ccc(CCNC(=O)CCn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1356848 26141 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 2 7 1.0 NS(=O)(=O)c1ccc(CCNC(=O)CCn2c(=O)c3cccn3c3cccnc32)cc1 nan
24687225 26146 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 8 0 8 3.1 COc1cccc(COC(=O)c2cc(S(=O)(=O)N3CCCCC3)ccc2N2CCOCC2)c1OC nan
CHEMBL1356898 26146 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 8 0 8 3.1 COc1cccc(COC(=O)c2cc(S(=O)(=O)N3CCCCC3)ccc2N2CCOCC2)c1OC nan
16015534 26151 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 4.3 CCOC(=O)CSc1nc2ccc(NC(=O)c3ccc(F)cc3)cc2s1 nan
CHEMBL1357001 26151 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 4.3 CCOC(=O)CSc1nc2ccc(NC(=O)c3ccc(F)cc3)cc2s1 nan
15989556 26152 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 1 9 2.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3cc(OC)c(OC)cc32)cc1 nan
CHEMBL1357013 26152 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 1 9 2.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3cc(OC)c(OC)cc32)cc1 nan
16025511 26166 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 4.0 CCN1c2ccccc2-c2nc(SCC(=O)Nc3cccc(C)c3C)ncc2S1(=O)=O nan
CHEMBL1357149 26166 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 4.0 CCN1c2ccccc2-c2nc(SCC(=O)Nc3cccc(C)c3C)ncc2S1(=O)=O nan
20903553 26184 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 2 6 3.0 COc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
CHEMBL1357354 26184 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 2 6 3.0 COc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
16031127 26195 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 5 5.2 CSc1ccc(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)cc1 nan
CHEMBL1357550 26195 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 5 5.2 CSc1ccc(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)cc1 nan
1146087 26199 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 5 4.7 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCc3ccc(F)cc3)n2)cc1 nan
CHEMBL1357694 26199 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 5 4.7 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCc3ccc(F)cc3)n2)cc1 nan
16027571 26220 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 9 2.9 CS(=O)(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
CHEMBL1358013 26220 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 9 2.9 CS(=O)(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
16027432 26230 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 1 9 3.1 Cc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)c3cccs3)nc2s1 nan
CHEMBL1358125 26230 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 1 9 3.1 Cc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)c3cccs3)nc2s1 nan
16012175 26234 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 5 4.7 Cc1ccccc1Cn1c2ccccc2c2cnn(CC(=O)NCCc3ccc(Cl)cc3)c(=O)c21 nan
CHEMBL1358188 26234 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 5 4.7 Cc1ccccc1Cn1c2ccccc2c2cnn(CC(=O)NCCc3ccc(Cl)cc3)c(=O)c21 nan
16011822 26239 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 7 4.2 CCOc1ccc(NC(=O)C2CCN(c3nnc(-n4c(C)ccc4C)s3)CC2)cc1 nan
CHEMBL1358209 26239 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 7 4.2 CCOc1ccc(NC(=O)C2CCN(c3nnc(-n4c(C)ccc4C)s3)CC2)cc1 nan
16015787 26240 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 6 6.0 COc1ccc(-c2cc(C(=O)Nc3c(C(=O)c4ccc(C)c(F)c4)oc4ccccc34)no2)cc1 nan
CHEMBL1358232 26240 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 6 6.0 COc1ccc(-c2cc(C(=O)Nc3c(C(=O)c4ccc(C)c(F)c4)oc4ccccc34)no2)cc1 nan
16009454 26275 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 CC(Oc1ccccc1)C(=O)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1358685 26275 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 CC(Oc1ccccc1)C(=O)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
16022826 26297 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 4.7 CCOc1ccc(NC(=O)C2CCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)CC2)cc1 nan
CHEMBL1358850 26297 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 4.7 CCOc1ccc(NC(=O)C2CCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)CC2)cc1 nan
654435 26319 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 6 4.2 O=C(CSc1nc2ccccc2o1)Nc1nc2ccccc2s1 nan
CHEMBL1359027 26319 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 6 4.2 O=C(CSc1nc2ccccc2o1)Nc1nc2ccccc2s1 nan
16009817 26326 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 4 1 7 5.0 Brc1cccc(-c2nnn3c2nc(NCc2ccc4c(c2)OCO4)c2ccccc23)c1 nan
CHEMBL1359062 26326 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 4 1 7 5.0 Brc1cccc(-c2nnn3c2nc(NCc2ccc4c(c2)OCO4)c2ccccc23)c1 nan
16009648 26398 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 5 4.3 COc1ccc(Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1359678 26398 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 5 4.3 COc1ccc(Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
16020569 26435 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 5 4.3 CCCn1cc(S(=O)(=O)c2ccc(C)cc2)c(=O)c2cc(F)c(N3CCCC3)cc21 nan
CHEMBL1360010 26435 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 5 4.3 CCCn1cc(S(=O)(=O)c2ccc(C)cc2)c(=O)c2cc(F)c(N3CCCC3)cc21 nan
135546909 26447 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 2 6 3.7 COc1ccc(CN2CCc3nc(SCC(=O)Nc4cc(C)cc(C)c4)[nH]c(=O)c3C2)cc1 nan
CHEMBL1360113 26447 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 2 6 3.7 COc1ccc(CN2CCc3nc(SCC(=O)Nc4cc(C)cc(C)c4)[nH]c(=O)c3C2)cc1 nan
3185716 26471 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 10 3 8 3.7 CC(C)c1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)cc1 nan
CHEMBL1360292 26471 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 10 3 8 3.7 CC(C)c1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)cc1 nan
2819025 26490 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 1 1 5 1.9 N#Cc1cnc2cc(-c3ccccc3)nn2c1N nan
CHEMBL1360465 26490 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 1 1 5 1.9 N#Cc1cnc2cc(-c3ccccc3)nn2c1N nan
2141195 26511 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 4.7 CCc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccccc1)cn2CC(=O)Nc1cc(C)ccc1C nan
CHEMBL1360707 26511 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 4.7 CCc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccccc1)cn2CC(=O)Nc1cc(C)ccc1C nan
135436940 26513 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 7 5.0 Oc1cc(-c2ccc(F)cc2)nc(SCc2nc(-c3cccc(Cl)c3)no2)n1 nan
CHEMBL1360713 26513 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 7 5.0 Oc1cc(-c2ccc(F)cc2)nc(SCc2nc(-c3cccc(Cl)c3)no2)n1 nan
16009483 26532 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 9 1 7 1.4 CCCCN(C)CCNC(=O)C1CCCN(S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)C1 nan
CHEMBL1360843 26532 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 9 1 7 1.4 CCCCN(C)CCNC(=O)C1CCCN(S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)C1 nan
2135565 26583 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCCO4)c3ccc(F)cc3c2=O)cc1 nan
CHEMBL1361368 26583 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCCO4)c3ccc(F)cc3c2=O)cc1 nan
7598414 26645 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 2.8 Cc1cccc(Cn2cccc(C(=O)Nc3cc(C)on3)c2=O)c1 nan
CHEMBL1361891 26645 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 2.8 Cc1cccc(Cn2cccc(C(=O)Nc3cc(C)on3)c2=O)c1 nan
1071174 26647 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 8 1 7 3.8 CCOc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3ccccc3c2=O)cc1 nan
CHEMBL1361894 26647 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 8 1 7 3.8 CCOc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3ccccc3c2=O)cc1 nan
857565 26712 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 4.2 Cc1cc(NC(=O)CSc2nc3c(C)c(C)ccc3cc2C)no1 nan
CHEMBL1362451 26712 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 4.2 Cc1cc(NC(=O)CSc2nc3c(C)c(C)ccc3cc2C)no1 nan
790083 26811 58 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 0 4 4.2 COc1ccccc1-c1nc(-c2ccc(Br)cc2)no1 nan
CHEMBL1363291 26811 58 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 0 4 4.2 COc1ccccc1-c1nc(-c2ccc(Br)cc2)no1 nan
2137970 26870 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.1 COc1ccc(S(=O)(=O)c2cn(CC(=O)Nc3ccccc3)c3ccc(Cl)cc3c2=O)cc1 nan
CHEMBL1363852 26870 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.1 COc1ccc(S(=O)(=O)c2cn(CC(=O)Nc3ccccc3)c3ccc(Cl)cc3c2=O)cc1 nan
22522543 26919 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 1 4 3.2 Cc1ccc(NC(=O)Cn2c(=O)c3cccn3c3ccccc32)cc1 nan
CHEMBL1364334 26919 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 1 4 3.2 Cc1ccc(NC(=O)Cn2c(=O)c3cccn3c3ccccc32)cc1 nan
1581690 26960 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 10 2 6 4.6 CCCCCOc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3cc(C)on3)cc2)cc1 nan
CHEMBL1364631 26960 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 10 2 6 4.6 CCCCCOc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3cc(C)on3)cc2)cc1 nan
1759638 26988 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 513 5 1 5 5.3 Cc1c(CCC(=O)N2CCC(C(=O)O)(c3ccccc3)CC2)c(=O)oc2cc3oc4c(c3cc12)CCCC4 nan
CHEMBL1364853 26988 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 513 5 1 5 5.3 Cc1c(CCC(=O)N2CCC(C(=O)O)(c3ccccc3)CC2)c(=O)oc2cc3oc4c(c3cc12)CCCC4 nan
2137118 27090 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 6 1 6 4.2 COc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccc(F)cc1)cn2CC(=O)Nc1ccc(C)cc1C nan
CHEMBL1365673 27090 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 6 1 6 4.2 COc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccc(F)cc1)cn2CC(=O)Nc1ccc(C)cc1C nan
16008395 27116 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 6 3.7 CCn1c(=O)cc(OCC(=O)Nc2cc(Cl)c(OC)cc2OC)c2ccccc21 nan
CHEMBL1365942 27116 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 6 3.7 CCn1c(=O)cc(OCC(=O)Nc2cc(Cl)c(OC)cc2OC)c2ccccc21 nan
2155747 27125 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 7 1 8 3.2 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(C)on3)o2)cc1 nan
CHEMBL1366006 27125 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 7 1 8 3.2 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(C)on3)o2)cc1 nan
16012964 27127 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 3 5.0 CCCN(Cc1cc2cc(C)ccc2nc1O)C(=O)c1cccc(Cl)c1 nan
CHEMBL1366015 27127 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 3 5.0 CCCN(Cc1cc2cc(C)ccc2nc1O)C(=O)c1cccc(Cl)c1 nan
2474394 27179 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 1 4 3.5 CCCn1c(=O)[nH]c(=O)c2c(C(F)(F)F)cc(-c3ccc(C)cc3)nc21 nan
CHEMBL1366444 27179 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 1 4 3.5 CCCn1c(=O)[nH]c(=O)c2c(C(F)(F)F)cc(-c3ccc(C)cc3)nc21 nan
17757029 27211 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 0 8 4.6 CCOC(=O)COc1ccc([N+](=O)[O-])cc1-c1ccnc2cc(-c3ccc(Cl)cc3)nn12 nan
CHEMBL1366773 27211 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 0 8 4.6 CCOC(=O)COc1ccc([N+](=O)[O-])cc1-c1ccnc2cc(-c3ccc(Cl)cc3)nn12 nan
5087310 27363 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 1 7 2.8 COc1cc2c(cc1OC)n(CC(=O)NC1CCCCCC1)n1c(C)cc(=O)nc21 nan
CHEMBL1367963 27363 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 1 7 2.8 COc1cc2c(cc1OC)n(CC(=O)NC1CCCCCC1)n1c(C)cc(=O)nc21 nan
4825943 27372 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 2.8 CC(Sc1nc2ccccc2c(=O)n1C)C(=O)Nc1ccc2c(c1)OCCO2 nan
CHEMBL1368013 27372 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 2.8 CC(Sc1nc2ccccc2c(=O)n1C)C(=O)Nc1ccc2c(c1)OCCO2 nan
16022825 27392 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 1 10 1.9 Cc1ccc(C)c(NC(=O)Cn2c(=O)n(Cc3nc(C)no3)c(=O)c3cc4c(cc32)OCO4)c1 nan
CHEMBL1368194 27392 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 1 10 1.9 Cc1ccc(C)c(NC(=O)Cn2c(=O)n(Cc3nc(C)no3)c(=O)c3cc4c(cc32)OCO4)c1 nan
709853 27435 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 5 2.7 COc1ccc(CNC(=O)c2cc3cccc(OC)c3oc2=O)cc1 nan
CHEMBL1368522 27435 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 5 2.7 COc1ccc(CNC(=O)c2cc3cccc(OC)c3oc2=O)cc1 nan
16019023 27455 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 8 1 6 2.9 CCOCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1368698 27455 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 8 1 6 2.9 CCOCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
1898787 27470 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 1.9 COC(=O)CSc1nc(N)c(C#N)c(-c2ccco2)c1C#N nan
CHEMBL1368847 27470 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 1.9 COC(=O)CSc1nc(N)c(C#N)c(-c2ccco2)c1C#N nan
16746213 27484 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 542 11 3 5 4.4 NC(=O)CC(NC(=O)Cc1ccc(Br)cc1)c1ccc(NCCc2ccccc2F)c([N+](=O)[O-])c1 nan
CHEMBL1368944 27484 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 542 11 3 5 4.4 NC(=O)CC(NC(=O)Cc1ccc(Br)cc1)c1ccc(NCCc2ccccc2F)c([N+](=O)[O-])c1 nan
15989069 27486 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 12 1 9 2.7 CCN(CC)C(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccc3c(c2)OCO3)c(=O)c2sccc21 nan
CHEMBL1368950 27486 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 12 1 9 2.7 CCN(CC)C(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccc3c(c2)OCO3)c(=O)c2sccc21 nan
3417357 27526 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 4 0 6 4.9 Cc1cc(C)c(Cn2c(=O)n(-c3ccccc3Cl)c(=O)c3c(C)c(C(=O)N(C)C)sc32)c(C)c1 nan
CHEMBL1369202 27526 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 4 0 6 4.9 Cc1cc(C)c(Cn2c(=O)n(-c3ccccc3Cl)c(=O)c3c(C)c(C(=O)N(C)C)sc32)c(C)c1 nan
4454678 27554 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 7 4.4 Cc1cc(OCC(=O)Nc2cc(-c3nn4c(C)nnc4s3)ccc2C)ccc1Cl nan
CHEMBL1369422 27554 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 7 4.4 Cc1cc(OCC(=O)Nc2cc(-c3nn4c(C)nnc4s3)ccc2C)ccc1Cl nan
16034378 27632 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 7 1 4 3.5 COc1ccc(C(=O)CCC(=O)Nc2cccc(C(C)=O)c2)cc1 nan
CHEMBL1369934 27632 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 7 1 4 3.5 COc1ccc(C(=O)CCC(=O)Nc2cccc(C(C)=O)c2)cc1 nan
16746462 27654 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 8 1 6 3.3 COc1cc(O)c(C(CCN2CCOCC2)c2ccc(N(C)C)cc2)c(OC)c1 nan
CHEMBL1370067 27654 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 8 1 6 3.3 COc1cc(O)c(C(CCN2CCOCC2)c2ccc(N(C)C)cc2)c(OC)c1 nan
3236293 27656 9 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 7 1 8 3.3 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccsc2c1=O nan
CHEMBL1370078 27656 9 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 7 1 8 3.3 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccsc2c1=O nan
5310561 27708 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.8 CCOc1ccccc1-c1nc(C(N)=O)c2nc(O)n(-c3ccc(F)cc3)c2n1 nan
CHEMBL1370473 27708 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.8 CCOc1ccccc1-c1nc(C(N)=O)c2nc(O)n(-c3ccc(F)cc3)c2n1 nan
667326 27721 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 7 1 5 3.5 CCOCCCNc1ncc2c(n1)CC(c1ccc(C)cc1)CC2=O nan
CHEMBL1370544 27721 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 7 1 5 3.5 CCOCCCNc1ncc2c(n1)CC(c1ccc(C)cc1)CC2=O nan
135546918 27734 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 2 6 3.6 CCCN1CCc2nc(SCC(=O)Nc3ccc(C)c(Cl)c3)nc(O)c2C1 nan
CHEMBL1370635 27734 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 2 6 3.6 CCCN1CCc2nc(SCC(=O)Nc3ccc(C)c(Cl)c3)nc(O)c2C1 nan
3628612 27765 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 5 4.4 CCc1nc(SCC(=O)NCCc2ccccc2)c2oc3ccccc3c2n1 nan
CHEMBL1370855 27765 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 5 4.4 CCc1nc(SCC(=O)NCCc2ccccc2)c2oc3ccccc3c2n1 nan
1348188 27911 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.6 Cc1cccc(-c2nc3cc(NC(=O)Cc4ccc(Cl)cc4)ccc3o2)c1 nan
CHEMBL1372034 27911 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.6 Cc1cccc(-c2nc3cc(NC(=O)Cc4ccc(Cl)cc4)ccc3o2)c1 nan
1854798 27936 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 1 0 5 3.6 Cn1c(=O)nc2n(-c3ccc(Br)cc3)c3cccc(Cl)c3cc-2c1=O nan
CHEMBL1372184 27936 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 1 0 5 3.6 Cn1c(=O)nc2n(-c3ccc(Br)cc3)c3cccc(Cl)c3cc-2c1=O nan
16019423 28007 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 1 9 5.0 CC(C)c1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
CHEMBL1372659 28007 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 1 9 5.0 CC(C)c1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
16031591 28068 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 6 3.4 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc(-c4coc(C)n4)cc3)CC2)cc1 nan
CHEMBL1373010 28068 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 6 3.4 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc(-c4coc(C)n4)cc3)CC2)cc1 nan
2684697 28143 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 5 3.7 COc1ccc(C)cc1NC(=O)c1ccc2c(=O)n3c(nc2c1)CCCCC3 nan
CHEMBL1373515 28143 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 5 3.7 COc1ccc(C)cc1NC(=O)c1ccc2c(=O)n3c(nc2c1)CCCCC3 nan
652717 28159 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 2 5 5.1 CCN1CCCC1CN(Cc1cc2cc(C)cc(C)c2nc1O)C(=O)Nc1ccccc1OC nan
CHEMBL1373605 28159 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 2 5 5.1 CCN1CCCC1CN(Cc1cc2cc(C)cc(C)c2nc1O)C(=O)Nc1ccccc1OC nan
16015413 28170 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 1 6 6.2 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccc(F)cc3)cc2s1 nan
CHEMBL1373657 28170 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 1 6 6.2 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccc(F)cc3)cc2s1 nan
16033161 28206 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 2 5 4.6 O=C(Nc1ccc(N2CCN(CCOc3ccc(Cl)cc3)CC2)c(C(=O)O)c1)c1ccc(F)cc1 nan
CHEMBL1373926 28206 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 2 5 4.6 O=C(Nc1ccc(N2CCN(CCOc3ccc(Cl)cc3)CC2)c(C(=O)O)c1)c1ccc(F)cc1 nan
16030696 28212 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 2.9 CC(=O)c1ccc(NC(=O)CSc2nc(-c3ccccc3C)nc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1374004 28212 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 2.9 CC(=O)c1ccc(NC(=O)CSc2nc(-c3ccccc3C)nc3c2c(=O)n(C)c(=O)n3C)cc1 nan
15997814 28257 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 6 4.2 COc1cc2nc(S)nc(NCc3cccc(Cl)c3)c2cc1OC nan
CHEMBL1374312 28257 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 6 4.2 COc1cc2nc(S)nc(NCc3cccc(Cl)c3)c2cc1OC nan
4521283 28265 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 4 1 5 4.7 O=C(CN1C(=O)c2ccccc2Sc2ccc(C(=O)N3CCOCC3)cc21)Nc1ccc(Cl)cc1F nan
CHEMBL1374381 28265 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 4 1 5 4.7 O=C(CN1C(=O)c2ccccc2Sc2ccc(C(=O)N3CCOCC3)cc21)Nc1ccc(Cl)cc1F nan
3734127 28303 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 4 4.0 CCc1ccc(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)cc1 nan
CHEMBL1374637 28303 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 4 4.0 CCc1ccc(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)cc1 nan
669593 28318 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 2 1 5 2.1 O=C(Nc1nccs1)c1ccc2c(c1)OCO2 nan
CHEMBL1374723 28318 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 2 1 5 2.1 O=C(Nc1nccs1)c1ccc2c(c1)OCO2 nan
656234 28359 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 7 3.3 O=c1c2ccccc2nc(CSc2[nH]cnc3ncnc2-3)n1-c1ccccc1 nan
CHEMBL1375001 28359 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 7 3.3 O=c1c2ccccc2nc(CSc2[nH]cnc3ncnc2-3)n1-c1ccccc1 nan
4074625 28373 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 3 3 6 0.3 COC(=O)c1ccccc1NC=C1C(=O)NC(=S)NC1=O nan
CHEMBL1375120 28373 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 3 3 6 0.3 COC(=O)c1ccccc1NC=C1C(=O)NC(=S)NC1=O nan
828451 28473 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 4 1 4 4.6 CCOc1ccc(Nc2nc3c(C)cccc3cc2C#N)cc1 nan
CHEMBL1375831 28473 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 4 1 4 4.6 CCOc1ccc(Nc2nc3c(C)cccc3cc2C#N)cc1 nan
7246250 28478 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 3 0 5 3.4 COc1cc(Br)cc2cc(S(=O)(=O)c3ccccc3)c(=O)oc12 nan
CHEMBL1375897 28478 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 3 0 5 3.4 COc1cc(Br)cc2cc(S(=O)(=O)c3ccccc3)c(=O)oc12 nan
16029523 28500 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 0 6 2.3 CN(C)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3ccc(F)cc3)CC1)CCS2 nan
CHEMBL1376205 28500 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 0 6 2.3 CN(C)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3ccc(F)cc3)CC1)CCS2 nan
4048244 28528 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 13 1 8 4.1 CCOC(=O)c1sc(-c2ccccc2)cc1NC(=O)c1ccc(S(=O)(=O)N(CCOC)CCOC)cc1 nan
CHEMBL1376427 28528 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 13 1 8 4.1 CCOC(=O)c1sc(-c2ccccc2)cc1NC(=O)c1ccc(S(=O)(=O)N(CCOC)CCOC)cc1 nan
1629947 28567 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 2 4 1.6 O=C1NC(=S)NC(=O)C1=Cc1ccc2c(c1)CCN2CCCCl nan
CHEMBL1376754 28567 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 2 4 1.6 O=C1NC(=S)NC(=O)C1=Cc1ccc2c(c1)CCN2CCCCl nan
1281315 28583 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 4 2 6 6.1 COc1ccc(-c2c3c(nc4sc(C(=O)Nc5ccccc5F)c(N)c24)CC(C)(C)CC3=O)cc1 nan
CHEMBL1376941 28583 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 4 2 6 6.1 COc1ccc(-c2c3c(nc4sc(C(=O)Nc5ccccc5F)c(N)c24)CC(C)(C)CC3=O)cc1 nan
3640458 28607 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 6 1 7 3.6 CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(C)C2 nan
CHEMBL1377235 28607 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 6 1 7 3.6 CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(C)C2 nan
4307577 28643 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 10 2 4 6.4 CC(C)c1ccc(Nc2cc(C(=O)NCCCN(C)Cc3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1377592 28643 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 10 2 4 6.4 CC(C)c1ccc(Nc2cc(C(=O)NCCCN(C)Cc3ccccc3)c3ccccc3n2)cc1 nan
16193746 28724 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 4 1 6 2.3 Cc1ccc(N2C(=O)C3C4C=CC(CN=C(S)N5CCN(c6ccccn6)CC5)(O4)C3C2=O)cc1 nan
CHEMBL1378295 28724 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 4 1 6 2.3 Cc1ccc(N2C(=O)C3C4C=CC(CN=C(S)N5CCN(c6ccccn6)CC5)(O4)C3C2=O)cc1 nan
2220966 28766 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 3 3.4 Cc1c(Cl)ccc2c(C(N)=O)cc(-c3ccccn3)nc12 nan
CHEMBL1378741 28766 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 3 3.4 Cc1c(Cl)ccc2c(C(N)=O)cc(-c3ccccn3)nc12 nan
7422753 28781 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 4 2.2 NC(=O)c1ccc(NC(=O)c2cccn(Cc3ccccc3)c2=O)cc1 nan
CHEMBL1378862 28781 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 4 2.2 NC(=O)c1ccc(NC(=O)c2cccn(Cc3ccccc3)c2=O)cc1 nan
2815317 28789 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 2 0 5 3.8 Cc1cc(C)c2c(n1)sc1c(=O)n(Cc3ccc(F)cc3)cnc12 nan
CHEMBL1378935 28789 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 2 0 5 3.8 Cc1cc(C)c2c(n1)sc1c(=O)n(Cc3ccc(F)cc3)cnc12 nan
16193948 28805 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 2 6 3.5 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N=C(S)N1CCN(c2ccccn2)CC1 nan
CHEMBL1379050 28805 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 2 6 3.5 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N=C(S)N1CCN(c2ccccn2)CC1 nan
24746968 28926 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.1 Cc1nc(Nc2ccccc2F)c2nnn(Cc3ccccc3Cl)c2n1 nan
CHEMBL1380147 28926 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.1 Cc1nc(Nc2ccccc2F)c2nnn(Cc3ccccc3Cl)c2n1 nan
725312 28949 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 6 3.0 CCn1cnc2sc(C(=O)Nc3ccccc3OC)c(C)c2c1=O nan
CHEMBL1380313 28949 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 6 3.0 CCn1cnc2sc(C(=O)Nc3ccccc3OC)c(C)c2c1=O nan
24792708 28982 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 7 3.3 COc1ccc(CNC(=O)CSc2nnc(NC(=O)c3ccccc3F)s2)cc1 nan
CHEMBL1380537 28982 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 7 3.3 COc1ccc(CNC(=O)CSc2nnc(NC(=O)c3ccccc3F)s2)cc1 nan
3604840 29012 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 5 3.7 COc1cccc(-c2cc(C(=O)Nc3cccnc3Cl)no2)c1 nan
CHEMBL1380782 29012 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 5 3.7 COc1cccc(-c2cc(C(=O)Nc3cccnc3Cl)no2)c1 nan
1980822 29165 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 4 3.9 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C)n2)cc1 nan
CHEMBL1382084 29165 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 4 3.9 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C)n2)cc1 nan
555289 29225 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 1 4 3.6 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccccc2C)n1 nan
CHEMBL1382619 29225 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 1 4 3.6 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccccc2C)n1 nan
9550495 29421 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.2 Cc1ccc(-c2nc3ncccc3o2)cc1NC(=O)COc1ccccc1 nan
CHEMBL1384380 29421 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.2 Cc1ccc(-c2nc3ncccc3o2)cc1NC(=O)COc1ccccc1 nan
7161160 29438 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 7 0.3 CCOc1ccccc1NS(=O)(=O)c1cn(C)c(=O)n(C)c1=O nan
CHEMBL1384530 29438 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 7 0.3 CCOc1ccccc1NS(=O)(=O)c1cn(C)c(=O)n(C)c1=O nan
4271811 29493 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 6 0 5 3.2 CCCc1nc2ccccc2c(=O)n1CC(=O)c1ccc(OC)cc1 nan
CHEMBL1384958 29493 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 6 0 5 3.2 CCCc1nc2ccccc2c(=O)n1CC(=O)c1ccc(OC)cc1 nan
2123263 29502 7 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 9 3.5 CCCn1c(N)c(-c2nc(C3CCCC3)c(C(=O)c3ccc(NC(C)=O)cc3)s2)c(=O)n(C)c1=O nan
CHEMBL1385062 29502 7 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 9 3.5 CCCn1c(N)c(-c2nc(C3CCCC3)c(C(=O)c3ccc(NC(C)=O)cc3)s2)c(=O)n(C)c1=O nan
3243476 29548 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 3.4 CC(=O)Nc1nc2c(c3c1c(=O)oc1ccccc13)CC(C)CC2 nan
CHEMBL1385469 29548 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 3.4 CC(=O)Nc1nc2c(c3c1c(=O)oc1ccccc13)CC(C)CC2 nan
645034 29600 4 None -6 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 5 2.9 N#Cc1cc2cc3c(cc2nc1N1CCCCC1)OCCO3 nan
CHEMBL1385946 29600 4 None -6 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 5 2.9 N#Cc1cc2cc3c(cc2nc1N1CCCCC1)OCCO3 nan
1233014 29621 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.4 Cc1ccc(C#N)c(SCC(=O)Nc2nccs2)n1 nan
CHEMBL1386142 29621 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.4 Cc1ccc(C#N)c(SCC(=O)Nc2nccs2)n1 nan
818106 29649 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 4 4.0 COc1ccc(-c2nc3c4ccccc4ccn3c2C=O)cc1 nan
CHEMBL1386316 29649 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 4 4.0 COc1ccc(-c2nc3c4ccccc4ccn3c2C=O)cc1 nan
2803005 29652 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 2 3.8 NC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1386328 29652 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 2 3.8 NC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
743778 29686 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 1 3 3.2 Cc1cc(-c2ccc(Cl)cc2)c(C#N)c(N)n1 nan
CHEMBL1386595 29686 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 1 3 3.2 Cc1cc(-c2ccc(Cl)cc2)c(C#N)c(N)n1 nan
1078300 29690 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.4 COc1ccccc1NC(=O)c1sc2ncn(Cc3cccc(C)c3)c(=O)c2c1C nan
CHEMBL1386617 29690 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.4 COc1ccccc1NC(=O)c1sc2ncn(Cc3cccc(C)c3)c(=O)c2c1C nan
2197659 29743 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 5 2.6 COc1ccc2c(c1)c(=O)oc1cc(OCC(=O)NC3CC3)ccc12 nan
CHEMBL1387003 29743 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 5 2.6 COc1ccc2c(c1)c(=O)oc1cc(OCC(=O)NC3CC3)ccc12 nan
2368754 29765 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 0 4 2.1 CCN1C(=O)C(=C2C=C(C)OC(C)=C2)C(=O)N(CC)C1=S nan
CHEMBL1387204 29765 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 0 4 2.1 CCN1C(=O)C(=C2C=C(C)OC(C)=C2)C(=O)N(CC)C1=S nan
1590813 29810 19 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 1 5.9 O=C(Nc1ccc(Cl)cc1Cl)c1ccc(-c2ccccc2)cc1 nan
CHEMBL1387594 29810 19 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 1 5.9 O=C(Nc1ccc(Cl)cc1Cl)c1ccc(-c2ccccc2)cc1 nan
16194196 29823 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 8 2.6 CCOC(=O)N1CCN(C(=O)CCCCCn2c(=S)[nH]c3cc4c(cc3c2=O)OCO4)CC1 nan
CHEMBL1387679 29823 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 8 2.6 CCOC(=O)N1CCN(C(=O)CCCCCn2c(=S)[nH]c3cc4c(cc3c2=O)OCO4)CC1 nan
3961803 29845 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 8 -0.6 Cn1nc(C(=O)OCC(=O)NC2CCS(=O)(=O)C2)c2ccccc2c1=O nan
CHEMBL1387823 29845 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 8 -0.6 Cn1nc(C(=O)OCC(=O)NC2CCS(=O)(=O)C2)c2ccccc2c1=O nan
649021 29894 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 5 1 9 3.8 Cc1cccc2cc(C(c3nnnn3Cc3ccc4c(c3)OCO4)N3CCC(C)CC3)c(O)nc12 nan
CHEMBL1388237 29894 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 5 1 9 3.8 Cc1cccc2cc(C(c3nnnn3Cc3ccc4c(c3)OCO4)N3CCC(C)CC3)c(O)nc12 nan
2565451 29911 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 7 2.1 CCOC(=O)c1sc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)nc1C nan
CHEMBL1388388 29911 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 7 2.1 CCOC(=O)c1sc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)nc1C nan
20874214 29938 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 3.7 CC(C)c1nn2c(=O)cc(COc3cccc(NC(=O)c4ccco4)c3)nc2s1 nan
CHEMBL1388517 29938 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 3.7 CC(C)c1nn2c(=O)cc(COc3cccc(NC(=O)c4ccco4)c3)nc2s1 nan
736044 29997 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 2 5 1.3 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1 nan
CHEMBL1389015 29997 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 2 5 1.3 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1 nan
3581200 30066 4 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 5 4.9 O=C(Nc1nc(-c2ccc(F)c(F)c2)cs1)c1ccc(OCC2CCCO2)cc1 nan
CHEMBL1389543 30066 4 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 5 4.9 O=C(Nc1nc(-c2ccc(F)c(F)c2)cs1)c1ccc(OCC2CCCO2)cc1 nan
2815149 30182 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 1 0 4 3.3 Cn1c2ccccc2n2c(=O)cc(-c3ccccc3)c(C#N)c12 nan
CHEMBL1390567 30182 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 1 0 4 3.3 Cn1c2ccccc2n2c(=O)cc(-c3ccccc3)c(C#N)c12 nan
1480454 30328 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 5 3.1 CN(C)c1nc(-c2cccnc2)nc(-c2ccccc2)c1C#N nan
CHEMBL1391874 30328 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 5 3.1 CN(C)c1nc(-c2cccnc2)nc(-c2ccccc2)c1C#N nan
3151961 30338 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 3 1 6 2.6 CC(C)c1nnc(NC(=O)c2ccc3c(c2)OCO3)s1 nan
CHEMBL1391972 30338 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 3 1 6 2.6 CC(C)c1nnc(NC(=O)c2ccc3c(c2)OCO3)s1 nan
2818919 30479 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 0 5 5.2 FC(F)(F)c1cc(-c2cccs2)nc2cc(-c3cccs3)nn12 nan
CHEMBL1393159 30479 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 0 5 5.2 FC(F)(F)c1cc(-c2cccs2)nc2cc(-c3cccs3)nn12 nan
3597887 30486 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 7 4.2 Cc1ccc(-c2nc(S(=O)(=O)c3ccc(C)cc3)c(SCC(=O)NCC3CCCO3)o2)cc1 nan
CHEMBL1393192 30486 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 7 4.2 Cc1ccc(-c2nc(S(=O)(=O)c3ccc(C)cc3)c(SCC(=O)NCC3CCCO3)o2)cc1 nan
6498520 30536 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 6 2.9 CN=C(S)N(Cc1cc2cc(C)ccc2n2nnnc12)CC(C)(C)CN(C)C nan
CHEMBL1393589 30536 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 6 2.9 CN=C(S)N(Cc1cc2cc(C)ccc2n2nnnc12)CC(C)(C)CN(C)C nan
938851 30569 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 1 5 3.7 Cc1ccc2nc(O)c(COC(=O)c3cccs3)cc2c1 nan
CHEMBL1393863 30569 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 1 5 3.7 Cc1ccc2nc(O)c(COC(=O)c3cccs3)cc2c1 nan
2810066 30579 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 2.9 COc1cc2nc(NC(=O)c3ccccc3)sc(=O)c2cc1OC nan
CHEMBL1393944 30579 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 2.9 COc1cc2nc(NC(=O)c3ccccc3)sc(=O)c2cc1OC nan
16010814 30591 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 3 0 7 4.3 Clc1cccc(N2CCN(c3nc4ccccc4c4nc(-c5cccnc5)nn34)CC2)c1 nan
CHEMBL1394069 30591 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 3 0 7 4.3 Clc1cccc(N2CCN(c3nc4ccccc4c4nc(-c5cccnc5)nn34)CC2)c1 nan
16018745 30605 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 3 5.9 Cc1ccc(Cn2c(C(=O)O)c(CNCc3ccccc3Cl)c3ccc(C)cc32)cc1 nan
CHEMBL1394183 30605 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 3 5.9 Cc1ccc(Cn2c(C(=O)O)c(CNCc3ccccc3Cl)c3ccc(C)cc32)cc1 nan
16030321 30606 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 3.8 COc1ccccc1C(=O)Nc1ccc(OCc2cc(=O)n3cccc(C)c3n2)cc1 nan
CHEMBL1394221 30606 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 3.8 COc1ccccc1C(=O)Nc1ccc(OCc2cc(=O)n3cccc(C)c3n2)cc1 nan
16019476 30608 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 4.4 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
CHEMBL1394231 30608 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 4.4 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
16012300 30613 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 2 5.0 Cc1ccc(NC(=O)c2ccc(-c3ccccc3)s2)cc1 nan
CHEMBL1394287 30613 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 2 5.0 Cc1ccc(NC(=O)c2ccc(-c3ccccc3)s2)cc1 nan
16015419 30644 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 8 1 6 6.3 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccc(C)cc3)cc2s1 nan
CHEMBL1394800 30644 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 8 1 6 6.3 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccc(C)cc3)cc2s1 nan
5297365 30653 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 5 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1cccc(C(F)(F)F)c1)C1CCN2CC1 nan
CHEMBL1394905 30653 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 5 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1cccc(C(F)(F)F)c1)C1CCN2CC1 nan
1308289 30654 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 0 6 4.2 CCS(=O)(=O)c1c(S(=O)(=O)CC)c2cc(C(C)(C)C)ccn2c1C(=O)c1ccc(F)cc1 nan
CHEMBL1394907 30654 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 0 6 4.2 CCS(=O)(=O)c1c(S(=O)(=O)CC)c2cc(C(C)(C)C)ccn2c1C(=O)c1ccc(F)cc1 nan
7338094 30669 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 5 5.2 Cc1ccn2c(Nc3ccccc3C)c(-c3ccc(N4CCOCC4)cc3)nc2c1 nan
CHEMBL1395018 30669 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 5 5.2 Cc1ccn2c(Nc3ccccc3C)c(-c3ccc(N4CCOCC4)cc3)nc2c1 nan
1598875 30671 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 7 3.4 COC(=O)c1ccccc1NC(=O)CSc1nc2sc3c(c2c(=O)[nH]1)CCCC3 nan
CHEMBL1395042 30671 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 7 3.4 COC(=O)c1ccccc1NC(=O)CSc1nc2sc3c(c2c(=O)[nH]1)CCCC3 nan
705204 30681 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 1 1 5 3.7 N#Cc1c(N)n(-c2cccc(Cl)c2)c2nc3ccccc3nc12 nan
CHEMBL1395126 30681 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 1 1 5 3.7 N#Cc1c(N)n(-c2cccc(Cl)c2)c2nc3ccccc3nc12 nan
16011870 30687 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 6 6.9 Cc1oc(-c2ccccc2F)nc1Cn1c(SCc2cccc(C(F)(F)F)c2)nc2ccncc21 nan
CHEMBL1395173 30687 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 6 6.9 Cc1oc(-c2ccccc2F)nc1Cn1c(SCc2cccc(C(F)(F)F)c2)nc2ccncc21 nan
16011750 30688 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 7 4.2 CCC(C(=O)NCc1cc(OC)ccc1OC)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1395174 30688 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 7 4.2 CCC(C(=O)NCc1cc(OC)ccc1OC)n1nc(C)c2sc3ccccc3c2c1=O nan
7150993 30690 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 Cc1ccc2nc(NC(=O)CSc3nccn3Cc3ccccc3)sc2c1 nan
CHEMBL1395184 30690 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 Cc1ccc2nc(NC(=O)CSc3nccn3Cc3ccccc3)sc2c1 nan
16022376 30716 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 4.7 O=C(CSc1nc2ccsc2c(=O)n1Cc1ccc(F)cc1)NCc1ccc(Cl)cc1 nan
CHEMBL1395536 30716 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 4.7 O=C(CSc1nc2ccsc2c(=O)n1Cc1ccc(F)cc1)NCc1ccc(Cl)cc1 nan
16008365 30743 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 5 3.9 COc1cccc(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)c1 nan
CHEMBL1395994 30743 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 5 3.9 COc1cccc(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)c1 nan
16016520 30751 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 2 2 2 3.4 Cc1cccc(NC(=O)c2ccc3[nH]c(C)cc(=O)c3c2)c1 nan
CHEMBL1396103 30751 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 2 2 2 3.4 Cc1cccc(NC(=O)c2ccc3[nH]c(C)cc(=O)c3c2)c1 nan
16012961 30773 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 3.2 COc1ccc(Cc2nc3c4cnn(-c5cccc(F)c5)c4ncn3n2)cc1 nan
CHEMBL1396439 30773 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 3.2 COc1ccc(Cc2nc3c4cnn(-c5cccc(F)c5)c4ncn3n2)cc1 nan
16011203 30793 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 3.8 CCc1nn(CC(=O)Nc2c(C)cc(C)cc2C)c(=O)c2cc3sccc3n12 nan
CHEMBL1396725 30793 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 3.8 CCc1nn(CC(=O)Nc2c(C)cc(C)cc2C)c(=O)c2cc3sccc3n12 nan
5300039 30817 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 2 5 4.7 Nc1c(C(=O)Nc2ccc(Br)cc2F)sc2nc3c(cc12)N1CCC3CC1 nan
CHEMBL1397016 30817 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 2 5 4.7 Nc1c(C(=O)Nc2ccc(Br)cc2F)sc2nc3c(cc12)N1CCC3CC1 nan
16029565 30831 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 5 4.0 Cc1ccc(C)c(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(F)ccc32)c1 nan
CHEMBL1397193 30831 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 5 4.0 Cc1ccc(C)c(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(F)ccc32)c1 nan
9114471 30844 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 7 1.5 N#Cc1cc(C#N)c(SCC(=O)N2CC(=O)Nc3ccccc32)nc1N nan
CHEMBL1397378 30844 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 7 1.5 N#Cc1cc(C#N)c(SCC(=O)N2CC(=O)Nc3ccccc32)nc1N nan
16029539 30848 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 1 5 4.7 Cc1ccc2c(c1)c(=O)c(C(=O)c1ccncc1)cn2CC(=O)Nc1ccc(C(C)C)cc1 nan
CHEMBL1397433 30848 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 1 5 4.7 Cc1ccc2c(c1)c(=O)c(C(=O)c1ccncc1)cn2CC(=O)Nc1ccc(C(C)C)cc1 nan
16021836 30851 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 4.1 CSc1ncc(C(=O)NCc2ccc(C)cc2)c(-c2ccccc2)n1 nan
CHEMBL1397498 30851 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 4.1 CSc1ncc(C(=O)NCc2ccc(C)cc2)c(-c2ccccc2)n1 nan
16024513 30853 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 4.8 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C)cc3Cl)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1397525 30853 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 4.8 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C)cc3Cl)c3nc(C)ccc3c2=O)cc1 nan
4069971 30879 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 8 1 4 5.3 CCCCNC(=O)c1cc(Sc2ccc(OCC)cc2)nc2ccccc12 nan
CHEMBL1397896 30879 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 8 1 4 5.3 CCCCNC(=O)c1cc(Sc2ccc(OCC)cc2)nc2ccccc12 nan
402652 30897 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 6 3.7 O=c1c2ccccc2nc2sc(Nc3cccc(Cl)c3)nn12 nan
CHEMBL1398128 30897 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 6 3.7 O=c1c2ccccc2nc2sc(Nc3cccc(Cl)c3)nn12 nan
15988651 30898 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 4 3.8 O=C(Nc1cccc(C(F)(F)F)c1)C1CCN(S(=O)(=O)c2cccs2)CC1 nan
CHEMBL1398130 30898 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 4 3.8 O=C(Nc1cccc(C(F)(F)F)c1)C1CCN(S(=O)(=O)c2cccs2)CC1 nan
135455820 30909 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 5 4.6 Oc1ncnc2c1sc1nc(C(F)F)cc(-c3ccccc3)c12 nan
CHEMBL1398293 30909 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 5 4.6 Oc1ncnc2c1sc1nc(C(F)F)cc(-c3ccccc3)c12 nan
16019015 30920 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 6 1 5 3.5 CC(C)CCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1398441 30920 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 6 1 5 3.5 CC(C)CCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16032326 30937 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 6 5.9 CN1CCc2c(sc(NC(=O)CSc3ccc(F)cc3)c2-c2nc3ccccc3s2)C1 nan
CHEMBL1398567 30937 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 6 5.9 CN1CCc2c(sc(NC(=O)CSc3ccc(F)cc3)c2-c2nc3ccccc3s2)C1 nan
2105201 30965 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 8 1 9 4.9 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3c(=O)n2-c2ccccc2)sc(C(C)=O)c1C nan
CHEMBL1398840 30965 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 8 1 9 4.9 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3c(=O)n2-c2ccccc2)sc(C(C)=O)c1C nan
16021149 31010 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 1 5 5.8 O=C(NC1CCCCC1)c1ccc(Cn2c(SCc3ccccc3)nc3cccnc32)cc1 nan
CHEMBL1399300 31010 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 1 5 5.8 O=C(NC1CCCCC1)c1ccc(Cn2c(SCc3ccccc3)nc3cccnc32)cc1 nan
8351751 31038 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 0 8 2.1 CCOc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)cc1 nan
CHEMBL1399515 31038 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 0 8 2.1 CCOc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)cc1 nan
1386490 31052 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 0 5 4.8 COc1cccc(OCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)c1 nan
CHEMBL1399670 31052 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 0 5 4.8 COc1cccc(OCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)c1 nan
16007871 31063 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 1 4 5.2 O=C(NCc1ccco1)c1ccc2c(c1)N(Cc1ccc(Cl)cc1)C(=O)c1ccccc1[S+]2[O-] nan
CHEMBL1399777 31063 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 1 4 5.2 O=C(NCc1ccco1)c1ccc2c(c1)N(Cc1ccc(Cl)cc1)C(=O)c1ccccc1[S+]2[O-] nan
16011403 31065 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 5 6.0 O=C(NCc1ccc(F)cc1)c1ccc(Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
CHEMBL1399789 31065 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 5 6.0 O=C(NCc1ccc(F)cc1)c1ccc(Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
7293305 31068 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 5 3.6 COCCn1ccc2c(OCC(=O)Nc3c(C)cc(C)cc3C)cccc2c1=O nan
CHEMBL1399845 31068 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 5 3.6 COCCn1ccc2c(OCC(=O)Nc3c(C)cc(C)cc3C)cccc2c1=O nan
16030115 31205 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.4 CCc1cccc(C)c1NC(=O)Cn1nc(C)c2nn(-c3ccc(Cl)cc3)c(C)c2c1=O nan
CHEMBL1401110 31205 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.4 CCc1cccc(C)c1NC(=O)Cn1nc(C)c2nn(-c3ccc(Cl)cc3)c(C)c2c1=O nan
1163266 31219 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 1 1 5 2.2 Cc1ccc(-c2cc3ncc(C#N)c(N)n3n2)cc1 nan
CHEMBL1401234 31219 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 1 1 5 2.2 Cc1ccc(-c2cc3ncc(C#N)c(N)n3n2)cc1 nan
16024855 31241 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 3 1 4 5.1 Cc1cc(C)cc(NC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
CHEMBL1401368 31241 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 3 1 4 5.1 Cc1cc(C)cc(NC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
16011339 31347 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 2 5 5.2 CCOC(=O)c1ccccc1NC(=O)NC(C)c1c(-n2cccc2)sc(C)c1C nan
CHEMBL1402306 31347 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 2 5 5.2 CCOC(=O)c1ccccc1NC(=O)NC(C)c1c(-n2cccc2)sc(C)c1C nan
16019019 31357 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 3.7 O=C(NCCc1ccccc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1402402 31357 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 3.7 O=C(NCCc1ccccc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16011789 31431 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 5 3.6 Cc1ccc(-n2ncc3c(=O)n(Cc4ccccc4C)cnc32)cc1C nan
CHEMBL1403021 31431 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 5 3.6 Cc1ccc(-n2ncc3c(=O)n(Cc4ccccc4C)cnc32)cc1C nan
7096324 31448 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 2 3 2.5 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(c2)CCCC3)cc1 nan
CHEMBL1403204 31448 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 2 3 2.5 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(c2)CCCC3)cc1 nan
135437062 31473 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 3 6 3.5 CCC(C)NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1ccc(C)c(Cl)c1 nan
CHEMBL1403479 31473 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 3 6 3.5 CCC(C)NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1ccc(C)c(Cl)c1 nan
16026084 31534 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 3 1 7 2.1 O=C(Nc1cccc(F)c1)c1cnc2sc(N3CCCC3)nn2c1=O nan
CHEMBL1404065 31534 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 3 1 7 2.1 O=C(Nc1cccc(F)c1)c1cnc2sc(N3CCCC3)nn2c1=O nan
15999042 31570 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 6 2.8 O=C(Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sccc21)NC1CCCCC1 nan
CHEMBL1404291 31570 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 6 2.8 O=C(Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sccc21)NC1CCCCC1 nan
1617675 31612 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 3 0 5 6.2 Cc1cccc(-c2nc3c4c(-c5ccccc5)c(-c5ccccc5)oc4ncn3n2)c1 nan
CHEMBL1404812 31612 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 3 0 5 6.2 Cc1cccc(-c2nc3c4c(-c5ccccc5)c(-c5ccccc5)oc4ncn3n2)c1 nan
2390567 31646 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 2 6 2.9 N#Cc1ccsc1NC(=O)COC(=O)c1cc(Br)ccc1O nan
CHEMBL1405202 31646 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 2 6 2.9 N#Cc1ccsc1NC(=O)COC(=O)c1cc(Br)ccc1O nan
15988048 31706 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 10 2 9 2.1 COc1cc2c(=O)n(CCC(=O)NCC3CCCO3)c(=O)n(CC(=O)Nc3c(C)cccc3C)c2cc1OC nan
CHEMBL1405772 31706 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 10 2 9 2.1 COc1cc2c(=O)n(CCC(=O)NCC3CCCO3)c(=O)n(CC(=O)Nc3c(C)cccc3C)c2cc1OC nan
16024912 31710 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.5 Cc1ccccc1CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1405829 31710 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.5 Cc1ccccc1CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
2991576 31912 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 6 2.6 CCCCc1nc2sc3c(=O)n(N)cnc3c2c2c1CCC2 nan
CHEMBL1407541 31912 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 6 2.6 CCCCc1nc2sc3c(=O)n(N)cnc3c2c2c1CCC2 nan
3583749 31949 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 7 3.0 COC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)sc2c1CCN(C)C2 nan
CHEMBL1407736 31949 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 7 3.0 COC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)sc2c1CCN(C)C2 nan
3245299 31959 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 2 7 2.7 CCOc1ccccc1-c1nc(C(N)=O)c2nc(O)n(-c3ccccc3)c2n1 nan
CHEMBL1407835 31959 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 2 7 2.7 CCOc1ccccc1-c1nc(C(N)=O)c2nc(O)n(-c3ccccc3)c2n1 nan
6485917 32008 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 9 1 8 2.6 COc1ccc(CNCCSc2nnnn2-c2ccccc2)c(OC)c1 nan
CHEMBL1408179 32008 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 9 1 8 2.6 COc1ccc(CNCCSc2nnnn2-c2ccccc2)c(OC)c1 nan
2265197 32017 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 2 2 4.3 O=C(Nc1ccccc1C(=O)Nc1ccccc1)c1ccccc1F nan
CHEMBL1408256 32017 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 2 2 4.3 O=C(Nc1ccccc1C(=O)Nc1ccccc1)c1ccccc1F nan
15989388 32102 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 7 1 6 3.3 CCc1ccc(NC(=O)Cn2c(=O)n(CCC(=O)N3CCc4ccccc4C3)c(=O)c3ccccc32)cc1 nan
CHEMBL1408914 32102 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 7 1 6 3.3 CCc1ccc(NC(=O)Cn2c(=O)n(CCC(=O)N3CCc4ccccc4C3)c(=O)c3ccccc32)cc1 nan
1082765 32191 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 8 1 6 2.9 COc1ccc(CCNC(=O)COc2ccc3c(C)cc(=O)oc3c2)cc1OC nan
CHEMBL1409638 32191 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 8 1 6 2.9 COc1ccc(CCNC(=O)COc2ccc3c(C)cc(=O)oc3c2)cc1OC nan
1913870 32218 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 7 2 6 3.1 O=C(/C=C\Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1ccccc1 nan
CHEMBL1409860 32218 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 7 2 6 3.1 O=C(/C=C\Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1ccccc1 nan
2527257 32271 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 7 2 7 1.7 COc1ccc(C(=O)OCC(=O)Nc2sccc2C(N)=O)cc1OC nan
CHEMBL1410234 32271 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 7 2 7 1.7 COc1ccc(C(=O)OCC(=O)Nc2sccc2C(N)=O)cc1OC nan
2201015 32281 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 3.3 Cc1ccc(-n2c3c(cc(C(=O)NCC(=O)c4ccccc4)c2=O)C(=O)CCC3)cc1 nan
CHEMBL1410319 32281 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 3.3 Cc1ccc(-n2c3c(cc(C(=O)NCC(=O)c4ccccc4)c2=O)C(=O)CCC3)cc1 nan
2135385 32313 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 7 1 7 4.1 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
CHEMBL1410565 32313 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 7 1 7 4.1 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
1160042 32333 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 0 5 3.9 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)Cc2ccc(Cl)cc2)n1 nan
CHEMBL1410783 32333 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 0 5 3.9 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)Cc2ccc(Cl)cc2)n1 nan
16232595 32345 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 6 3.1 Cc1cc(C)c(C#N)c(SCC(=O)Nc2cccc(S(=O)(=O)N3CCCC3)c2)n1 nan
CHEMBL1410891 32345 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 6 3.1 Cc1cc(C)c(C#N)c(SCC(=O)Nc2cccc(S(=O)(=O)N3CCCC3)c2)n1 nan
1963060 32359 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 0 6 2.6 COCCn1c(-c2ccccc2)nc2c(c(=O)c3ccccc3n2C)c1=O nan
CHEMBL1411041 32359 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 0 6 2.6 COCCn1c(-c2ccccc2)nc2c(c(=O)c3ccccc3n2C)c1=O nan
1301263 32401 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 6 4.6 COc1ccc(CC(=O)Nc2ccc(-c3nnc(-c4ccccc4)o3)cc2)cc1OC nan
CHEMBL1411349 32401 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 6 4.6 COc1ccc(CC(=O)Nc2ccc(-c3nnc(-c4ccccc4)o3)cc2)cc1OC nan
2353143 32578 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 4 4.4 COc1cc(SC)ccc1C(=O)Nc1ncc(Cl)cc1Cl nan
CHEMBL1412778 32578 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 4 4.4 COc1cc(SC)ccc1C(=O)Nc1ncc(Cl)cc1Cl nan
135402203 32658 14 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 1 6 3.5 COc1ccc(OCCSc2nc(O)c3ccccc3n2)cc1 nan
CHEMBL1413382 32658 14 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 1 6 3.5 COc1ccc(OCCSc2nc(O)c3ccccc3n2)cc1 nan
8722509 32676 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 7 1 7 3.6 CC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccncc3)n2C2CC2)cc1 nan
CHEMBL1413558 32676 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 7 1 7 3.6 CC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccncc3)n2C2CC2)cc1 nan
3240816 32679 3 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 3 0 6 2.0 COC(=O)c1cn(C)c2ccc(S(=O)(=O)N3CC(C)CC(C)C3)cc2c1=O nan
CHEMBL1413578 32679 3 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 3 0 6 2.0 COC(=O)c1cn(C)c2ccc(S(=O)(=O)N3CC(C)CC(C)C3)cc2c1=O nan
3546772 32713 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 8 1 4 5.1 CC(C)OCCCNC(=O)c1cc(Sc2ccc(F)cc2)nc2ccccc12 nan
CHEMBL1413820 32713 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 8 1 4 5.1 CC(C)OCCCNC(=O)c1cc(Sc2ccc(F)cc2)nc2ccccc12 nan
2216801 32736 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.2 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCCC3)no1 nan
CHEMBL1414005 32736 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.2 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCCC3)no1 nan
16011480 32783 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 5 6.1 Cc1cccc(Cn2c(SCc3ccc(C(=O)NC4CCCCC4)cc3)nc3ccncc32)c1 nan
CHEMBL1414437 32783 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 5 6.1 Cc1cccc(Cn2c(SCc3ccc(C(=O)NC4CCCCC4)cc3)nc3ccncc32)c1 nan
3185714 32816 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 9 3 8 2.9 Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)c1 nan
CHEMBL1414702 32816 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 9 3 8 2.9 Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)c1 nan
16024849 32889 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 4.7 CC(NC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1)c1ccccc1 nan
CHEMBL1415340 32889 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 4.7 CC(NC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1)c1ccccc1 nan
1997619 32916 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 1 0 6 3.4 O=c1nc2sc3ccccc3n2c(=O)n1-c1ccc(Cl)c(Cl)c1 nan
CHEMBL1415577 32916 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 1 0 6 3.4 O=c1nc2sc3ccccc3n2c(=O)n1-c1ccc(Cl)c(Cl)c1 nan
601275 32943 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 7 2.7 CCc1nnc(NC(=O)CSc2nc(C)cc(C)c2C#N)s1 nan
CHEMBL1415875 32943 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 7 2.7 CCc1nnc(NC(=O)CSc2nc(C)cc(C)c2C#N)s1 nan
15988188 32968 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 7 2 4 2.9 CCCCCn1c(=O)[nH]c2cc(C(=O)NCc3ccc(F)cc3)ccc2c1=O nan
CHEMBL1416073 32968 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 7 2 4 2.9 CCCCCn1c(=O)[nH]c2cc(C(=O)NCc3ccc(F)cc3)ccc2c1=O nan
2135587 33022 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(F)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
CHEMBL1416515 33022 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(F)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
1829959 33028 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 1 6 4.6 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccccc2)cc1)c1cccs1 nan
CHEMBL1416570 33028 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 1 6 4.6 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccccc2)cc1)c1cccs1 nan
4044817 33045 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 4 1 6 4.1 CC(OC(=O)c1ccc2c(=O)n3c(nc2c1)CCCCC3)C(=O)Nc1ccc(F)cc1Cl nan
CHEMBL1416742 33045 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 4 1 6 4.1 CC(OC(=O)c1ccc2c(=O)n3c(nc2c1)CCCCC3)C(=O)Nc1ccc(F)cc1Cl nan
16012432 33046 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 2 5 3.0 O=C(NCc1cccc(Cl)c1)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 nan
CHEMBL1416749 33046 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 2 5 3.0 O=C(NCc1cccc(Cl)c1)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 nan
16033988 33062 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 2 0 5 2.8 Cc1ccc(-n2ncc3c(N(C)C)ncnc32)cc1Cl nan
CHEMBL1416927 33062 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 2 0 5 2.8 Cc1ccc(-n2ncc3c(N(C)C)ncnc32)cc1Cl nan
16031129 33127 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 2 6 4.5 COc1ccc(OC)c(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)c1 nan
CHEMBL1417406 33127 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 2 6 4.5 COc1ccc(OC)c(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)c1 nan
16018805 33142 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 6 3.3 COc1ccc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)cc1Cl nan
CHEMBL1417571 33142 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 6 3.3 COc1ccc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)cc1Cl nan
1490637 33185 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 2 5 4.5 COc1ccc(NC(=O)c2ccccc2Sc2ccc(NC(C)=O)nc2)cc1 nan
CHEMBL1417935 33185 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 2 5 4.5 COc1ccc(NC(=O)c2ccccc2Sc2ccc(NC(C)=O)nc2)cc1 nan
5768421 33208 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 9 1 6 3.8 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)c(C)c2)C1c1ccncc1 nan
CHEMBL1418118 33208 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 9 1 6 3.8 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)c(C)c2)C1c1ccncc1 nan
16025701 33257 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 9 3.7 COc1ccc(-n2nnc(-c3nsc(NC(=O)c4cccc(C)c4)n3)c2C)cc1OC nan
CHEMBL1418579 33257 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 9 3.7 COc1ccc(-n2nnc(-c3nsc(NC(=O)c4cccc(C)c4)n3)c2C)cc1OC nan
1248279 33280 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 2 7 3.9 COc1ccccc1Nc1nc(N)nc(-c2oc3ccccc3c2C)n1 nan
CHEMBL1418732 33280 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 2 7 3.9 COc1ccccc1Nc1nc(N)nc(-c2oc3ccccc3c2C)n1 nan
2082778 33315 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 3 2 3 3.6 COc1ccc(Br)c(C(=O)Nc2nc3ccccc3[nH]2)c1 nan
CHEMBL1419051 33315 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 3 2 3 3.6 COc1ccc(Br)c(C(=O)Nc2nc3ccccc3[nH]2)c1 nan
7708945 33333 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 1 4 4.3 Nc1c(-c2ccc(Cl)cc2)cnc2c(-c3ccccc3)cnn12 nan
CHEMBL1419219 33333 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 1 4 4.3 Nc1c(-c2ccc(Cl)cc2)cnc2c(-c3ccccc3)cnn12 nan
656027 33426 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 1 7 4.2 COc1ccc(CCN2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccs2)cc1OC nan
CHEMBL1420005 33426 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 1 7 4.2 COc1ccc(CCN2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccs2)cc1OC nan
16457257 33442 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 1 1 5 3.5 Cc1ccccc1-c1nc2c3ccccc3nc(S)n2n1 nan
CHEMBL1420123 33442 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 1 1 5 3.5 Cc1ccccc1-c1nc2c3ccccc3nc(S)n2n1 nan
5049250 33456 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 2.6 O=C(COc1cccc2cccnc12)NNC(=S)Nc1ccccc1 nan
CHEMBL1420194 33456 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 2.6 O=C(COc1cccc2cccnc12)NNC(=S)Nc1ccccc1 nan
2518728 33510 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.3 Cc1nn(Cc2ccc(F)cc2)c2sc(C(=O)Nc3nccs3)cc12 nan
CHEMBL1420654 33510 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.3 Cc1nn(Cc2ccc(F)cc2)c2sc(C(=O)Nc3nccs3)cc12 nan
1975568 33698 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 0 6 4.4 COc1ccc2c(c1)c1nc3ccccc3nc1n2CCCN1C(=O)c2ccccc2C1=O nan
CHEMBL1422285 33698 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 0 6 4.4 COc1ccc2c(c1)c1nc3ccccc3nc1n2CCCN1C(=O)c2ccccc2C1=O nan
2952481 33818 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 7 2 5 3.6 CCCC(=O)Nc1ccc(C(=O)Nc2ccc([N+](=O)[O-])cc2OC)cc1 nan
CHEMBL1423274 33818 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 7 2 5 3.6 CCCC(=O)Nc1ccc(C(=O)Nc2ccc([N+](=O)[O-])cc2OC)cc1 nan
4204373 33900 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 2 6 3.5 COc1cc2nc(S)nc(NCc3ccccc3)c2cc1OC nan
CHEMBL1423864 33900 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 2 6 3.5 COc1cc2nc(S)nc(NCc3ccccc3)c2cc1OC nan
3208003 33926 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cc(C)ccc2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1424112 33926 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cc(C)ccc2nc1SCC(=O)Nc1cc(C)on1 nan
4329755 34049 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 3 6.3 O=C(Cc1sc(-c2ccccc2Cl)nc1-c1ccccc1)Nc1ccccc1 nan
CHEMBL1425135 34049 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 3 6.3 O=C(Cc1sc(-c2ccccc2Cl)nc1-c1ccccc1)Nc1ccccc1 nan
2293921 34099 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 3 5 1.5 NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(NC(=O)C3CC3)cc2)cc1 nan
CHEMBL1425666 34099 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 3 5 1.5 NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(NC(=O)C3CC3)cc2)cc1 nan
2009311 34118 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 6 4.6 O=C(O)CSc1ncnc2c1sc1nc(-c3ccccc3)c3c(c12)CCC3 nan
CHEMBL1425879 34118 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 6 4.6 O=C(O)CSc1ncnc2c1sc1nc(-c3ccccc3)c3c(c12)CCC3 nan
3434681 34232 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 3 5 3.9 COc1ccccc1NS(=O)(=O)c1cccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 nan
CHEMBL1426649 34232 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 3 5 3.9 COc1ccccc1NS(=O)(=O)c1cccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 nan
3430748 34235 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 3 5 2.1 COc1ccc2c3c([nH]c2c1)C1CC2C(CC(O)C(OC)C2CO)CN1CC3 nan
CHEMBL1426665 34235 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 3 5 2.1 COc1ccc2c3c([nH]c2c1)C1CC2C(CC(O)C(OC)C2CO)CN1CC3 nan
16195448 34296 1 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 1 3 4.7 Cc1cccc(NC(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)n1 nan
CHEMBL1427245 34296 1 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 1 3 4.7 Cc1cccc(NC(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)n1 nan
1206713 34426 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 5 2.9 Cc1cccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc12 nan
CHEMBL1428460 34426 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 5 2.9 Cc1cccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc12 nan
2085163 34457 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 3.7 CCOc1ncccc1C(=O)Nc1ccc2nc(C)sc2c1 nan
CHEMBL1428703 34457 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 3.7 CCOc1ncccc1C(=O)Nc1ccc2nc(C)sc2c1 nan
3138587 34489 3 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 5 10 -2.3 CN(C)c1ccc2nc3c(=O)[nH]c(=O)nc-3n(CC(O)C(O)C(O)CO)c2c1 nan
CHEMBL1428985 34489 3 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 5 10 -2.3 CN(C)c1ccc2nc3c(=O)[nH]c(=O)nc-3n(CC(O)C(O)C(O)CO)c2c1 nan
1454920 34580 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 4.7 CCc1ccc2c(c1)cc(CN(C(S)=Nc1ccccc1C)C1CC1)c1nnnn12 nan
CHEMBL1429692 34580 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 4.7 CCc1ccc2c(c1)cc(CN(C(S)=Nc1ccccc1C)C1CC1)c1nnnn12 nan
748627 34607 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 4 4.7 Cc1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1 nan
CHEMBL1429854 34607 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 4 4.7 Cc1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1 nan
1478328 34672 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 0 5 3.0 CCc1nc2oc3ccc(C)cc3c(=O)c2cc1C(=O)OC nan
CHEMBL1430305 34672 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 0 5 3.0 CCc1nc2oc3ccc(C)cc3c(=O)c2cc1C(=O)OC nan
2950980 34726 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 4 6 3.8 O=C(O)c1cc(S(=O)(=O)O)cc(Nc2c3ccccc3nc3ccccc23)c1O nan
CHEMBL1430778 34726 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 4 6 3.8 O=C(O)c1cc(S(=O)(=O)O)cc(Nc2c3ccccc3nc3ccccc23)c1O nan
3452486 34814 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1cccc(NC(=O)CSc2ncnc3c2oc2ccccc23)c1 nan
CHEMBL1431571 34814 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1cccc(NC(=O)CSc2ncnc3c2oc2ccccc23)c1 nan
2031268 34847 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 2 0 5 4.2 Cc1cccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccccc2)c1 nan
CHEMBL1431855 34847 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 2 0 5 4.2 Cc1cccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccccc2)c1 nan
16030582 35046 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 2 7 4.1 Cc1ccc2[nH]c(CSc3nnc(NC(=O)COc4ccccc4F)s3)cc(=O)c2c1 nan
CHEMBL1433463 35046 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 2 7 4.1 Cc1ccc2[nH]c(CSc3nnc(NC(=O)COc4ccccc4F)s3)cc(=O)c2c1 nan
16014372 35060 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 4 4.7 Cc1ccc(CSc2ncc(Cl)c(C(=O)NCc3ccccc3)n2)cc1 nan
CHEMBL1433681 35060 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 4 4.7 Cc1ccc(CSc2ncc(Cl)c(C(=O)NCc3ccccc3)n2)cc1 nan
24980276 35090 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 2 8 2.9 CCOC(=O)c1c(NC(=O)COC(=O)CCOc2ccccc2C)sc(C(=O)NC)c1C nan
CHEMBL1434167 35090 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 2 8 2.9 CCOC(=O)c1c(NC(=O)COC(=O)CCOc2ccccc2C)sc(C(=O)NC)c1C nan
17757032 35093 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 1 0 4 4.6 Clc1ccc2c(c1)-c1c(cnc3cc(-c4ccccc4)nn13)CO2 nan
CHEMBL1434219 35093 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 1 0 4 4.6 Clc1ccc2c(c1)-c1c(cnc3cc(-c4ccccc4)nn13)CO2 nan
16018775 35094 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 5 3.7 Cc1cc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)ccc1Br nan
CHEMBL1434221 35094 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 5 3.7 Cc1cc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)ccc1Br nan
16018825 35105 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 8 2.4 COc1ccc(CCNC(=O)CCn2c(=O)c3cccn3c3cccnc32)c(OC)c1OC nan
CHEMBL1434453 35105 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 8 2.4 COc1ccc(CCNC(=O)CCn2c(=O)c3cccn3c3cccnc32)c(OC)c1OC nan
15989503 35112 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 7 3.2 Cc1cccc(NC(=O)Cn2c(=O)n(CCCS(=O)(=O)C3CCCCC3)c(=O)c3ccccc32)c1 nan
CHEMBL1434580 35112 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 7 3.2 Cc1cccc(NC(=O)Cn2c(=O)n(CCCS(=O)(=O)C3CCCCC3)c(=O)c3ccccc32)c1 nan
16034196 35113 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 9 2 7 5.2 CCOC(=O)c1ccc(N2CCN(c3cccc(OC)c3)CC2)c(NC(=O)Nc2ccc(OCC)cc2)c1 nan
CHEMBL1434618 35113 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 9 2 7 5.2 CCOC(=O)c1ccc(N2CCN(c3cccc(OC)c3)CC2)c(NC(=O)Nc2ccc(OCC)cc2)c1 nan
16030773 35122 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 4 5.0 Cc1cccc(OCC(=O)Nc2cc(-c3ccccc3F)nn2-c2ccccc2)c1 nan
CHEMBL1434674 35122 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 4 5.0 Cc1cccc(OCC(=O)Nc2cc(-c3ccccc3F)nn2-c2ccccc2)c1 nan
4153411 35150 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 4 5.6 Cc1cc(C)cc(OCC(=O)Nc2ccc(-c3nc4ccccc4s3)cc2)c1 nan
CHEMBL1435020 35150 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 4 5.6 Cc1cc(C)cc(OCC(=O)Nc2ccc(-c3nc4ccccc4s3)cc2)c1 nan
9516939 35151 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 3 1 6 3.2 COc1ccc2oc(C(=O)Nc3nnc(C)s3)c(C)c2c1 nan
CHEMBL1435035 35151 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 3 1 6 3.2 COc1ccc2oc(C(=O)Nc3nnc(C)s3)c(C)c2c1 nan
16016693 35166 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 2 4 5.5 CC(C)Oc1ccc(CNC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1 nan
CHEMBL1435186 35166 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 2 4 5.5 CC(C)Oc1ccc(CNC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1 nan
16026116 35183 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 9 1.7 COc1cccc(CNC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)c1OC nan
CHEMBL1435357 35183 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 9 1.7 COc1cccc(CNC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)c1OC nan
1821611 35193 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 5 5.9 COc1ccc(NC(=O)c2c(NC(=O)COc3ccc(Cl)cc3)sc3c2CCCCC3)cc1 nan
CHEMBL1435471 35193 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 5 5.9 COc1ccc(NC(=O)c2c(NC(=O)COc3ccc(Cl)cc3)sc3c2CCCCC3)cc1 nan
1251337 35201 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.2 COc1ccc(CNC(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)cc1 nan
CHEMBL1435587 35201 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.2 COc1ccc(CNC(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)cc1 nan
16010614 35226 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 5.2 Cc1ccc(CNc2nc3ccccc3c3nc(-c4cccc(C)c4)nn23)cc1 nan
CHEMBL1435932 35226 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 5.2 Cc1ccc(CNc2nc3ccccc3c3nc(-c4cccc(C)c4)nn23)cc1 nan
16025971 35229 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 2 6 4.1 Cc1ccc(NC(=O)CSc2nc(-c3ccccc3Cl)nc3cc(=O)[nH]n23)c(C)c1 nan
CHEMBL1436000 35229 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 2 6 4.1 Cc1ccc(NC(=O)CSc2nc(-c3ccccc3Cl)nc3cc(=O)[nH]n23)c(C)c1 nan
16023620 35238 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 3 5 3.4 Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(CS(=O)(=O)Cc2cccc(F)c2)N3)cc1 nan
CHEMBL1436076 35238 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 3 5 3.4 Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(CS(=O)(=O)Cc2cccc(F)c2)N3)cc1 nan
16001329 35259 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 0 7 4.9 COc1ccc(-c2nn(C)c3sc(C(=O)N4CCN(c5cccc(C)c5C)CC4)cc23)cc1OC nan
CHEMBL1436335 35259 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 0 7 4.9 COc1ccc(-c2nn(C)c3sc(C(=O)N4CCN(c5cccc(C)c5C)CC4)cc23)cc1OC nan
16015802 35265 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 4 6.5 Cc1ccc(SCC(=O)Nc2cccc(-c3nc4cc(Cl)ccc4o3)c2C)cc1 nan
CHEMBL1436447 35265 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 4 6.5 Cc1ccc(SCC(=O)Nc2cccc(-c3nc4cc(Cl)ccc4o3)c2C)cc1 nan
16008886 35270 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.3 COc1ccc(CNC(=O)c2cc3c(=O)oc4ccc(C)cc4c3s2)c(OC)c1 nan
CHEMBL1436510 35270 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.3 COc1ccc(CNC(=O)c2cc3c(=O)oc4ccc(C)cc4c3s2)c(OC)c1 nan
16024495 35310 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 9 1 7 3.3 COc1ccc(CCNC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3ccc(C)nc32)cc1OC nan
CHEMBL1437062 35310 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 9 1 7 3.3 COc1ccc(CCNC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3ccc(C)nc32)cc1OC nan
16019037 35319 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 0 6 4.6 CCOC(=O)c1cnc2cc(-c3ccc(OCC)cc3)nn2c1-c1ccccc1 nan
CHEMBL1437136 35319 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 0 6 4.6 CCOC(=O)c1cnc2cc(-c3ccc(OCC)cc3)nn2c1-c1ccccc1 nan
16030417 35343 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1cccc(OCC(=O)Nc2ccccc2OCc2cc(=O)n3cc(C)ccc3n2)c1 nan
CHEMBL1437458 35343 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1cccc(OCC(=O)Nc2ccccc2OCc2cc(=O)n3cc(C)ccc3n2)c1 nan
15987619 35346 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 4 5.7 CCCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c1cccc(Cl)c1 nan
CHEMBL1437513 35346 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 4 5.7 CCCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c1cccc(Cl)c1 nan
16027516 35354 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccccc1C(=O)Nc1cccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)c1 nan
CHEMBL1437665 35354 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccccc1C(=O)Nc1cccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)c1 nan
2986974 35358 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 5 4.5 Cc1cc(-c2nc3ncccc3o2)ccc1NC(=O)COc1ccccc1C nan
CHEMBL1437693 35358 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 5 4.5 Cc1cc(-c2nc3ncccc3o2)ccc1NC(=O)COc1ccccc1C nan
16025598 35416 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 1 7 4.1 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(C)S3(=O)=O)cc1 nan
CHEMBL1438111 35416 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 1 7 4.1 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(C)S3(=O)=O)cc1 nan
16012435 35429 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 0 4 3.7 CCc1nn(Cc2cccc(F)c2)c(=O)c2cc3cc(C)ccc3n12 nan
CHEMBL1438209 35429 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 0 4 3.7 CCc1nn(Cc2cccc(F)c2)c(=O)c2cc3cc(C)ccc3n12 nan
16014909 35519 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 2 3.7 Cc1ccc2c(c1)cc(C(=O)NCc1ccccc1C)n2C nan
CHEMBL1439084 35519 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 2 3.7 Cc1ccc2c(c1)cc(C(=O)NCc1ccccc1C)n2C nan
992393 35541 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 8 1 6 5.0 CCOC(=O)c1cnc2c(C)cc(Cl)cc2c1NCCc1ccc(OC)c(OC)c1 nan
CHEMBL1439287 35541 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 8 1 6 5.0 CCOC(=O)c1cnc2c(C)cc(Cl)cc2c1NCCc1ccc(OC)c(OC)c1 nan
2767956 35568 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 3 4.9 CSc1cc(-c2ccc(Cl)cc2)c(C(=O)NC(C)C)s1 nan
CHEMBL1439494 35568 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 3 4.9 CSc1cc(-c2ccc(Cl)cc2)c(C(=O)NC(C)C)s1 nan
3116122 35597 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 7 2.1 COc1ccc(NC(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 nan
CHEMBL1439707 35597 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 7 2.1 COc1ccc(NC(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 nan
16016094 35642 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 7 5.1 COc1ccc(-c2noc(-c3ccc(NC4CCCCC4)c([N+](=O)[O-])c3)n2)cc1 nan
CHEMBL1440140 35642 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 7 5.1 COc1ccc(-c2noc(-c3ccc(NC4CCCCC4)c([N+](=O)[O-])c3)n2)cc1 nan
1630787 35688 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 5 2 7 3.3 CC(C)(C)NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1 nan
CHEMBL1440595 35688 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 5 2 7 3.3 CC(C)(C)NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1 nan
16014413 35698 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 4 4.7 Cc1ccccc1CSc1ncc(Cl)c(C(=O)NCc2ccccc2)n1 nan
CHEMBL1440676 35698 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 4 4.7 Cc1ccccc1CSc1ncc(Cl)c(C(=O)NCc2ccccc2)n1 nan
15989176 35793 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 9 1 5 3.2 CCCCNC(=O)CCCn1c(=O)c2ccccc2n(Cc2ccccc2C)c1=O nan
CHEMBL1441599 35793 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 9 1 5 3.2 CCCCNC(=O)CCCn1c(=O)c2ccccc2n(Cc2ccccc2C)c1=O nan
16008898 35815 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 6 3.5 CCOC(=O)c1cccc(NC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
CHEMBL1441757 35815 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 6 3.5 CCOC(=O)c1cccc(NC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
1374312 35825 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 2 6 2.6 COc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 nan
CHEMBL1441823 35825 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 2 6 2.6 COc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 nan
979004 35829 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 0 10 2.6 CC(C)(C)c1nnc2sc(SCC(=O)c3ccc4c(c3)OCCO4)nn2c1=O nan
CHEMBL1441873 35829 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 0 10 2.6 CC(C)(C)c1nnc2sc(SCC(=O)c3ccc4c(c3)OCCO4)nn2c1=O nan
1860569 35853 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 2 0 5 4.2 Cc1ccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccccc2)cc1 nan
CHEMBL1442098 35853 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 2 0 5 4.2 Cc1ccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccccc2)cc1 nan
5302651 36043 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 5 3.7 CCc1ccc(NC(=O)CSc2nc(C)cc(COC)c2C#N)cc1 nan
CHEMBL1443840 36043 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 5 3.7 CCc1ccc(NC(=O)CSc2nc(C)cc(COC)c2C#N)cc1 nan
12006099 36081 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 13 1 7 4.1 CCCN(CCC)C(=O)Cn1c(=O)n(CCCCCC(=O)Nc2ccccc2)c(=O)c2sccc21 nan
CHEMBL1444172 36081 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 13 1 7 4.1 CCCN(CCC)C(=O)Cn1c(=O)n(CCCCCC(=O)Nc2ccccc2)c(=O)c2sccc21 nan
16019024 36115 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 7 1 6 2.5 COCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1444500 36115 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 7 1 6 2.5 COCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16034708 36118 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 5 3.6 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3)c2n1 nan
CHEMBL1444524 36118 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 5 3.6 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3)c2n1 nan
16016687 36138 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 2 5 4.8 COc1ccc(CNC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1OC nan
CHEMBL1444758 36138 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 2 5 4.8 COc1ccc(CNC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1OC nan
3238164 36163 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 3 3.1 O=C(CCN1CCN(c2ccc(F)cc2)CC1)Nc1ccc(F)cc1 nan
CHEMBL1444967 36163 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 3 3.1 O=C(CCN1CCN(c2ccc(F)cc2)CC1)Nc1ccc(F)cc1 nan
2296239 36164 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 8 1 6 2.7 CCn1c(SCC(=O)NCCOc2ccccc2)nc2ccccc2c1=O nan
CHEMBL1444971 36164 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 8 1 6 2.7 CCn1c(SCC(=O)NCCOc2ccccc2)nc2ccccc2c1=O nan
657584 36175 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 0 5 3.9 CC(C)Cc1nc(N2CCN(C(=O)Cc3ccccc3)CC2)c(C#N)c2c1COC(C)(C)C2 nan
CHEMBL1445051 36175 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 0 5 3.9 CC(C)Cc1nc(N2CCN(C(=O)Cc3ccccc3)CC2)c(C#N)c2c1COC(C)(C)C2 nan
15988979 36228 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 7 3.2 O=C(CCn1c(=O)c2sccc2n(CC(=O)Nc2ccccc2)c1=O)NCc1ccccc1Cl nan
CHEMBL1445545 36228 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 7 3.2 O=C(CCn1c(=O)c2sccc2n(CC(=O)Nc2ccccc2)c1=O)NCc1ccccc1Cl nan
16023569 36253 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 0 8 3.1 CC(=O)c1ccc(N2CCN(C(=O)CCn3cnc4onc(-c5ccc(F)cc5)c4c3=O)CC2)cc1 nan
CHEMBL1445781 36253 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 0 8 3.1 CC(=O)c1ccc(N2CCN(C(=O)CCn3cnc4onc(-c5ccc(F)cc5)c4c3=O)CC2)cc1 nan
7157939 36278 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 2 3 3.1 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1cc(Cl)ccc1Cl nan
CHEMBL1446030 36278 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 2 3 3.1 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1cc(Cl)ccc1Cl nan
1480468 36340 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 5 3.9 CC(C)Nc1nc(-c2ccncc2)nc(-c2ccccc2)c1C#N nan
CHEMBL1446611 36340 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 5 3.9 CC(C)Nc1nc(-c2ccncc2)nc(-c2ccccc2)c1C#N nan
2195706 36367 7 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 1 8 2.8 CCOC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
CHEMBL1446861 36367 7 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 1 8 2.8 CCOC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
16010637 36405 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 4.7 CCN(Cc1ccccc1)C(=O)c1cc2c(=O)[nH]c3ccc(C)cc3c2s1 nan
CHEMBL1447092 36405 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 4.7 CCN(Cc1ccccc1)C(=O)c1cc2c(=O)[nH]c3ccc(C)cc3c2s1 nan
2130696 36503 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.9 N#C/C(C(=O)NCc1ccco1)=C1/SC=C(c2ccccc2)N1c1ccccc1 nan
CHEMBL1447960 36503 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.9 N#C/C(C(=O)NCc1ccco1)=C1/SC=C(c2ccccc2)N1c1ccccc1 nan
4583349 36550 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 2 5 2.2 Cc1ccc(NC(=O)CCn2c(=O)[nH]c3ccsc3c2=O)cc1F nan
CHEMBL1448388 36550 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 2 5 2.2 Cc1ccc(NC(=O)CCn2c(=O)[nH]c3ccsc3c2=O)cc1F nan
5396132 36632 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 0 5 3.7 COc1cc(/C=C2/C(=O)ON=C2C)ccc1OCc1ccccc1F nan
CHEMBL1448972 36632 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 0 5 3.7 COc1cc(/C=C2/C(=O)ON=C2C)ccc1OCc1ccccc1F nan
1201887 36658 8 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 0 3 4.0 Cc1cccc(CSc2nc3c(cc2C#N)CCC3)c1 nan
CHEMBL1449126 36658 8 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 0 3 4.0 Cc1cccc(CSc2nc3c(cc2C#N)CCC3)c1 nan
649163 36662 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 0 5 3.0 CCN(CC)S(=O)(=O)c1ccc(Cl)c(C(=O)Oc2cccnc2)c1 nan
CHEMBL1449162 36662 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 0 5 3.0 CCN(CC)S(=O)(=O)c1ccc(Cl)c(C(=O)Oc2cccnc2)c1 nan
16019152 36719 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 7 4.0 Cc1ccccc1Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
CHEMBL1449607 36719 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 7 4.0 Cc1ccccc1Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
16017274 36738 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.6 CCN(CC)c1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
CHEMBL1449789 36738 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.6 CCN(CC)c1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
15996185 36746 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 2 4 4.7 CCC(C)NC(=O)CCC(=O)Nc1ccc2nc(N3CC(C)CC(C)C3)cc(C)c2c1 nan
CHEMBL1449862 36746 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 2 4 4.7 CCC(C)NC(=O)CCC(=O)Nc1ccc2nc(N3CC(C)CC(C)C3)cc(C)c2c1 nan
15989912 36750 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 7 5.4 Cc1cc(C)n(-c2nc3ccccc3nc2Nc2ccc(Cl)c(C(=O)OC(C)C)c2)n1 nan
CHEMBL1449881 36750 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 7 5.4 Cc1cc(C)n(-c2nc3ccccc3nc2Nc2ccc(Cl)c(C(=O)OC(C)C)c2)n1 nan
16020571 36911 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 4.2 CCn1cc(S(=O)(=O)c2cc(C)cc(C)c2)c(=O)c2cc(F)c(N3CCCC3)cc21 nan
CHEMBL1451264 36911 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 4.2 CCn1cc(S(=O)(=O)c2cc(C)cc(C)c2)c(=O)c2cc(F)c(N3CCCC3)cc21 nan
5058847 37054 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 6 3.0 COc1cc(NC(=O)Cn2c(C)cc3ccccc3c2=O)cc(OC)c1OC nan
CHEMBL1452293 37054 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 6 3.0 COc1cc(NC(=O)Cn2c(C)cc3ccccc3c2=O)cc(OC)c1OC nan
15988482 37184 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.4 Cc1ccc(C(=O)c2cn(Cc3ccc(F)cc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1453340 37184 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.4 Cc1ccc(C(=O)c2cn(Cc3ccc(F)cc3)c3nc(C)ccc3c2=O)cc1 nan
16019909 37192 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 0 8 3.8 COc1cc(-c2noc(-c3cc4cccc(C)c4oc3=O)n2)cc(OC)c1OC nan
CHEMBL1453424 37192 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 0 8 3.8 COc1cc(-c2noc(-c3cc4cccc(C)c4oc3=O)n2)cc(OC)c1OC nan
16024781 37233 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 4 1.9 O=C1C(=O)N(C2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)CCN1Cc1ccccc1 nan
CHEMBL1453815 37233 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 4 1.9 O=C1C(=O)N(C2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)CCN1Cc1ccccc1 nan
16024608 37243 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 1 7 3.5 COc1ccc(CCNC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc1OC nan
CHEMBL1453881 37243 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 1 7 3.5 COc1ccc(CCNC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc1OC nan
3940076 37256 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 1 5 3.3 Cc1ccc(CNc2nc3nc(C)c(Cl)c(C)n3n2)cc1 nan
CHEMBL1453947 37256 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 1 5 3.3 Cc1ccc(CNc2nc3nc(C)c(Cl)c(C)n3n2)cc1 nan
1604929 37261 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 5 4.6 CCCCn1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Cl)cc2)c1 nan
CHEMBL1453974 37261 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 5 4.6 CCCCn1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Cl)cc2)c1 nan
707946 37287 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 5 3.0 O=C(Nc1nc2nccc(-c3ccccc3)n2n1)c1ccccc1 nan
CHEMBL1454141 37287 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 5 3.0 O=C(Nc1nc2nccc(-c3ccccc3)n2n1)c1ccccc1 nan
16010581 37303 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 2.9 Cc1cc(C)cc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)c1 nan
CHEMBL1454246 37303 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 2.9 Cc1cc(C)cc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)c1 nan
15988208 37371 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 9 1.7 COC(=O)c1cccnc1-n1c(=O)c2cccnc2n(CC(=O)Nc2cccc(C)c2)c1=O nan
CHEMBL1454833 37371 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 9 1.7 COC(=O)c1cccnc1-n1c(=O)c2cccnc2n(CC(=O)Nc2cccc(C)c2)c1=O nan
5123668 37428 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 10 1 7 5.2 CCc1ccc(NC(=O)CSc2nc3c(sc4ccccc43)c(=O)n2CCN(CC)CC)cc1 nan
CHEMBL1455415 37428 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 10 1 7 5.2 CCc1ccc(NC(=O)CSc2nc3c(sc4ccccc43)c(=O)n2CCN(CC)CC)cc1 nan
135421575 37483 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 2 4 3.3 CCn1c(=O)c(-c2nc3ccccc3[nH]2)c(O)c2ccccc21 nan
CHEMBL1455904 37483 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 2 4 3.3 CCn1c(=O)c(-c2nc3ccccc3[nH]2)c(O)c2ccccc21 nan
914701 37510 8 None -7 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 1 0 4 4.3 CCc1nc2sc3c(Cl)ncnc3c2c2c1CCCC2 nan
CHEMBL1456130 37510 8 None -7 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 1 0 4 4.3 CCc1nc2sc3c(Cl)ncnc3c2c2c1CCCC2 nan
2023595 37634 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 4.1 COc1cccc(NC(=O)CSc2ncnc3c2oc2ccccc23)c1 nan
CHEMBL1457309 37634 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 4.1 COc1cccc(NC(=O)CSc2ncnc3c2oc2ccccc23)c1 nan
16024557 37670 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3ccc(Cl)cc3)cn(CC(=O)NC3CCCCC3)c2n1 nan
CHEMBL1457615 37670 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3ccc(Cl)cc3)cn(CC(=O)NC3CCCCC3)c2n1 nan
20920344 37693 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 4.4 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5cccs5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1457782 37693 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 4.4 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5cccs5)CC4)nnc(C)c3c2C)cc1 nan
3245484 37823 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 8 2 7 1.9 COc1cc2[nH]c(=O)n(CCC(=O)NC3CCN(Cc4ccccc4)CC3)c(=O)c2cc1OC nan
CHEMBL1458892 37823 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 8 2 7 1.9 COc1cc2[nH]c(=O)n(CCC(=O)NC3CCN(Cc4ccccc4)CC3)c(=O)c2cc1OC nan
2467173 37845 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 9 1 11 1.4 C=CCn1c(SCC(=O)c2c(N)n(CCC)c(=O)n(C)c2=O)nnc1-c1ccncc1 nan
CHEMBL1459057 37845 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 9 1 11 1.4 C=CCn1c(SCC(=O)c2c(N)n(CCC)c(=O)n(C)c2=O)nnc1-c1ccncc1 nan
3185309 37872 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 10 3 9 3.7 COc1ccc(OC)c(C(C(=O)NC2CCCCC2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2OC)c1 nan
CHEMBL1459257 37872 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 10 3 9 3.7 COc1ccc(OC)c(C(C(=O)NC2CCCCC2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2OC)c1 nan
2910207 37889 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 7 1 6 3.9 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Br)c1)c1ccco1 nan
CHEMBL1459409 37889 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 7 1 6 3.9 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Br)c1)c1ccco1 nan
2138506 38022 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 2 6 3.0 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N=C(S)N1CCN(C(=O)OCC)CC1 nan
CHEMBL1460540 38022 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 2 6 3.0 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N=C(S)N1CCN(C(=O)OCC)CC1 nan
1995746 38035 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 3 8 0.9 NC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccccn3)n2N)cc1 nan
CHEMBL1460633 38035 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 3 8 0.9 NC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccccn3)n2N)cc1 nan
1511731 38063 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 2.9 COc1ccc(C(=O)Nc2nc(C)c3cc4c(cc3n2)OCO4)cc1 nan
CHEMBL1460863 38063 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 2.9 COc1ccc(C(=O)Nc2nc(C)c3cc4c(cc3n2)OCO4)cc1 nan
4340474 38114 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 6 2 6 2.1 CCCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3 nan
CHEMBL1461327 38114 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 6 2 6 2.1 CCCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3 nan
2331607 38144 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 1 5 2.7 O=C(Nc1ccccn1)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O nan
CHEMBL1461642 38144 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 1 5 2.7 O=C(Nc1ccccn1)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O nan
4594455 38204 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 0 7 3.9 CSc1nc(N2CCN(c3ccccc3)CC2)cc(N2CCN(c3ccccc3)CC2)n1 nan
CHEMBL1462148 38204 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 0 7 3.9 CSc1nc(N2CCN(c3ccccc3)CC2)cc(N2CCN(c3ccccc3)CC2)n1 nan
661296 38235 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 2 1 3.2 CCc1c(C(=O)O)[nH]c2ccc(Br)cc12 nan
CHEMBL1462380 38235 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 2 1 3.2 CCc1c(C(=O)O)[nH]c2ccc(Br)cc12 nan
3183779 38266 5 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 5 1 9 3.7 Oc1nc2cc3c(cc2cc1C(c1nnnn1Cc1ccccc1)N1CCCCCC1)OCCO3 nan
CHEMBL1462671 38266 5 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 5 1 9 3.7 Oc1nc2cc3c(cc2cc1C(c1nnnn1Cc1ccccc1)N1CCCCCC1)OCCO3 nan
5418960 38285 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 1 1 4 3.3 O=c1c2cc3c(nc2[nH]c(=S)n1-c1ccccc1)CCCC3 nan
CHEMBL1462820 38285 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 1 1 4 3.3 O=c1c2cc3c(nc2[nH]c(=S)n1-c1ccccc1)CCCC3 nan
2766000 38317 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 10 1 8 3.9 COCCCn1c(SCc2ccc(OC)cc2)nc2cc(OC)c(OC)cc2c1=N nan
CHEMBL1463048 38317 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 10 1 8 3.9 COCCCn1c(SCc2ccc(OC)cc2)nc2cc(OC)c(OC)cc2c1=N nan
16188024 38340 2 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 4 5.0 Cc1ccc2nc(O)c3cc(C(=O)N(C)c4ccccc4C)sc3c2c1 nan
CHEMBL1463271 38340 2 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 4 5.0 Cc1ccc2nc(O)c3cc(C(=O)N(C)c4ccccc4C)sc3c2c1 nan
4429285 38354 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 7 3.7 COC(=O)c1ccc(Nc2ncnc3c2cnn3-c2cccc(C)c2)cc1 nan
CHEMBL1463413 38354 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 7 3.7 COC(=O)c1ccc(Nc2ncnc3c2cnn3-c2cccc(C)c2)cc1 nan
1738267 38359 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 8 1 4 5.2 O=C(CCC(=O)OCC(=O)c1ccc(-c2ccccc2)cc1)Nc1cccc(Cl)c1 nan
CHEMBL1463488 38359 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 8 1 4 5.2 O=C(CCC(=O)OCC(=O)c1ccc(-c2ccccc2)cc1)Nc1cccc(Cl)c1 nan
3761375 38483 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 0 4 4.3 CSc1nc(C)c2c(n1)N(c1ccc(C(C)C)cc1)CC2 nan
CHEMBL1464437 38483 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 0 4 4.3 CSc1nc(C)c2c(n1)N(c1ccc(C(C)C)cc1)CC2 nan
2044631 38538 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 2 4 4.3 Cc1cc(C)c(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)c(C)c1 nan
CHEMBL1464810 38538 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 2 4 4.3 Cc1cc(C)c(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)c(C)c1 nan
2372173 38584 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 4 4.4 CC(=O)c1sc(NC(=O)c2ccccc2F)nc1-c1ccccc1 nan
CHEMBL1465138 38584 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 4 4.4 CC(=O)c1sc(NC(=O)c2ccccc2F)nc1-c1ccccc1 nan
2988623 38806 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 0 6 3.2 CCOc1ccc(C(=O)N2CCN(c3cnn(-c4ccccc4)c(=O)c3Cl)CC2)cc1 nan
CHEMBL1466802 38806 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 0 6 3.2 CCOc1ccc(C(=O)N2CCN(c3cnn(-c4ccccc4)c(=O)c3Cl)CC2)cc1 nan
2428874 38826 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 2 4 1.9 O=C(Nc1cccc2c1C(=O)NC2=O)c1cccnc1Cl nan
CHEMBL1466996 38826 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 2 4 1.9 O=C(Nc1cccc2c1C(=O)NC2=O)c1cccnc1Cl nan
3574259 38846 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
CHEMBL1467198 38846 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
16007702 38878 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 5 2.6 CCn1cc(C(=O)NCCc2ccc(C)cc2)c(=O)c2cc(S(=O)(=O)N(C)C)ccc21 nan
CHEMBL1467433 38878 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 5 2.6 CCn1cc(C(=O)NCCc2ccc(C)cc2)c(=O)c2cc(S(=O)(=O)N(C)C)ccc21 nan
663318 38891 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 0 6 4.3 CC1CCN(c2nc3ccccc3nc2C(C#N)C(=O)OC2CCCCC2)CC1 nan
CHEMBL1467520 38891 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 0 6 4.3 CC1CCN(c2nc3ccccc3nc2C(C#N)C(=O)OC2CCCCC2)CC1 nan
2820576 38990 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 6 5.4 Cc1csc2sc(-c3ccnc(SCC(=O)NCc4ccccc4)n3)c(C)c12 nan
CHEMBL1468435 38990 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 6 5.4 Cc1csc2sc(-c3ccnc(SCC(=O)NCc4ccccc4)n3)c(C)c12 nan
970728 39008 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 2 2 5.0 Cc1cc(C)nc(NC(S)=Nc2cccc(Cl)c2Cl)c1 nan
CHEMBL1468575 39008 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 2 2 5.0 Cc1cc(C)nc(NC(S)=Nc2cccc(Cl)c2Cl)c1 nan
4294342 39011 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 2 2 3.6 Cc1cc2cc(CNC(=O)NC3CCCCC3)ccc2n1C nan
CHEMBL1468608 39011 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 2 2 3.6 Cc1cc2cc(CNC(=O)NC3CCCCC3)ccc2n1C nan
648454 39018 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 4 3.4 Cc1cc(C)nc(N2CCC(C(=O)Nc3ccc4c(c3)CCC4)CC2)n1 nan
CHEMBL1468653 39018 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 4 3.4 Cc1cc(C)nc(N2CCC(C(=O)Nc3ccc4c(c3)CCC4)CC2)n1 nan
7202588 39102 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 7 2.9 COC(=O)c1ccc2nc(NC(=O)CCS(=O)(=O)c3ccccc3)sc2c1 nan
CHEMBL1469363 39102 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 7 2.9 COC(=O)c1ccc2nc(NC(=O)CCS(=O)(=O)c3ccccc3)sc2c1 nan
1073207 39242 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 0 9 2.4 COc1ccc(-n2nnnc2SCC(=O)c2ccc3c(c2)OCCO3)cc1 nan
CHEMBL1470594 39242 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 0 9 2.4 COc1ccc(-n2nnnc2SCC(=O)c2ccc3c(c2)OCCO3)cc1 nan
3615142 39243 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 3 4.0 Cc1c(C(=O)Nc2cccnc2Cl)oc2ccccc12 nan
CHEMBL1470599 39243 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 3 4.0 Cc1c(C(=O)Nc2cccnc2Cl)oc2ccccc12 nan
16009952 39480 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 7 0.9 Cc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1F nan
CHEMBL1472658 39480 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 7 0.9 Cc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1F nan
1892783 39488 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 3 1 5 4.8 Cc1ccc(-c2nnc3c4ccccc4c(C)nn23)cc1NC(=O)c1ccccc1 nan
CHEMBL1472759 39488 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 3 1 5 4.8 Cc1ccc(-c2nnc3c4ccccc4c(C)nn23)cc1NC(=O)c1ccccc1 nan
16008277 39492 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 4 1 5 5.8 Cc1cc(N2CCC(C(=O)Nc3ccc(F)cc3F)CC2)n2nc(C)c(-c3ccc(Cl)cc3)c2n1 nan
CHEMBL1472790 39492 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 4 1 5 5.8 Cc1cc(N2CCC(C(=O)Nc3ccc(F)cc3F)CC2)n2nc(C)c(-c3ccc(Cl)cc3)c2n1 nan
16015830 39495 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 4 5.1 O=C(COc1ccccc1F)Nc1ccc(-c2nc3ccccc3s2)cc1 nan
CHEMBL1472798 39495 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 4 5.1 O=C(COc1ccccc1F)Nc1ccc(-c2nc3ccccc3s2)cc1 nan
16030736 39505 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 3 5.3 CC(C)(C)C(=O)Nc1cc(-c2cccc(Br)c2)nn1-c1ccccc1 nan
CHEMBL1472994 39505 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 3 5.3 CC(C)(C)C(=O)Nc1cc(-c2cccc(Br)c2)nn1-c1ccccc1 nan
16015144 39508 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 1 5 4.6 O=C(/C=C/c1ccc(Cl)cc1)Nc1nc(-c2cccs2)ns1 nan
CHEMBL1472998 39508 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 1 5 4.6 O=C(/C=C/c1ccc(Cl)cc1)Nc1nc(-c2cccs2)ns1 nan
16010790 39536 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 1 7 2.7 COc1ccc(Cn2c(=O)c3cccnc3n(CC(=O)Nc3ccc(C)c(F)c3)c2=O)cc1 nan
CHEMBL1473410 39536 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 1 7 2.7 COc1ccc(Cn2c(=O)c3cccnc3n(CC(=O)Nc3ccc(C)c(F)c3)c2=O)cc1 nan
16009809 39538 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 2 5 5.9 COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1 nan
CHEMBL1473436 39538 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 2 5 5.9 COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1 nan
16009067 39543 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 2 1 3 5.5 Cc1ccc2nc(Cl)c3cc(C(=O)NC4CCCCC4)sc3c2c1 nan
CHEMBL1473455 39543 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 2 1 3 5.5 Cc1ccc2nc(Cl)c3cc(C(=O)NC4CCCCC4)sc3c2c1 nan
864758 39550 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 6 2.1 CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnn3)cc2)cc1 nan
CHEMBL1473580 39550 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 6 2.1 CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnn3)cc2)cc1 nan
16010866 39551 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 1 7 2.9 COc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1Cl nan
CHEMBL1473610 39551 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 1 7 2.9 COc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1Cl nan
16008902 39553 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 4 3.3 Cc1cccc(CCNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
CHEMBL1473624 39553 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 4 3.3 Cc1cccc(CCNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
4425770 39559 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 4.4 Cc1cccc(-c2nnc(SCC(=O)Nc3ccc(C)c(C)c3)o2)c1 nan
CHEMBL1473697 39559 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 4.4 Cc1cccc(-c2nnc(SCC(=O)Nc3ccc(C)c(C)c3)o2)c1 nan
16025407 39564 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 6 1 6 5.2 Cc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2cccc(F)c2)S3(=O)=O)cc1F nan
CHEMBL1473728 39564 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 6 1 6 5.2 Cc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2cccc(F)c2)S3(=O)=O)cc1F nan
15989780 39610 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 1 5 4.9 Clc1ccc(CCNc2nc3cc(Cl)c(Cl)cc3n3cnnc23)cc1 nan
CHEMBL1474477 39610 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 1 5 4.9 Clc1ccc(CCNc2nc3cc(Cl)c(Cl)cc3n3cnnc23)cc1 nan
16034729 39622 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 1 7 5.0 COc1ccc(-c2cn3nc(N4CCC(C(=O)Nc5cccc(Cl)c5)CC4)sc3n2)cc1 nan
CHEMBL1474594 39622 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 1 7 5.0 COc1ccc(-c2cn3nc(N4CCC(C(=O)Nc5cccc(Cl)c5)CC4)sc3n2)cc1 nan
16012452 39634 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 2 5 2.4 O=C(NCc1ccccc1)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 nan
CHEMBL1474806 39634 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 2 5 2.4 O=C(NCc1ccccc1)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 nan
16020997 39636 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.9 Cc1ccc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1F nan
CHEMBL1474813 39636 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.9 Cc1ccc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1F nan
16012520 39664 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 2 5 4.9 CC(=O)Nc1ccc(NC(=O)CCc2c(C)nc3c(c(C)nn3-c3ccccc3)c2C)cc1 nan
CHEMBL1475217 39664 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 2 5 4.9 CC(=O)Nc1ccc(NC(=O)CCc2c(C)nc3c(c(C)nn3-c3ccccc3)c2C)cc1 nan
16008390 39669 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 4 4.2 CCc1ccc(CNC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)cc1 nan
CHEMBL1475336 39669 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 4 4.2 CCc1ccc(CNC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)cc1 nan
3225367 39673 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 3 5.8 Cc1cccc(C)c1NC(=O)c1cc2sccc2n1Cc1ccc(F)cc1 nan
CHEMBL1475367 39673 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 3 5.8 Cc1cccc(C)c1NC(=O)c1cc2sccc2n1Cc1ccc(F)cc1 nan
1983981 39681 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 0 4 5.2 Cc1ccc(-c2nn3c(-c4ccc(C)cc4)nnc3c3ccccc23)cc1 nan
CHEMBL1475431 39681 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 0 4 5.2 Cc1ccc(-c2nn3c(-c4ccc(C)cc4)nnc3c3ccccc23)cc1 nan
16030137 39695 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 7 1 7 3.6 CCOc1ccccc1CNC(=O)Cn1nc(C)c2nn(-c3ccc(Cl)cc3)c(C)c2c1=O nan
CHEMBL1475622 39695 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 7 1 7 3.6 CCOc1ccccc1CNC(=O)Cn1nc(C)c2nn(-c3ccc(Cl)cc3)c(C)c2c1=O nan
16016540 39697 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 2 2 3.7 Cc1cc(=O)c2cc(C(=O)Nc3cccc(C)c3C)ccc2[nH]1 nan
CHEMBL1475643 39697 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 2 2 3.7 Cc1cc(=O)c2cc(C(=O)Nc3cccc(C)c3C)ccc2[nH]1 nan
16026533 39705 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 7 4.0 COc1ccc(OC)c(NC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)c1 nan
CHEMBL1475722 39705 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 7 4.0 COc1ccc(OC)c(NC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)c1 nan
16030897 39709 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 1 6 4.8 COc1ccc(-c2cn3nc(SCC(=O)Nc4cccc(C)c4C)ccc3n2)cc1 nan
CHEMBL1475786 39709 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 1 6 4.8 COc1ccc(-c2cn3nc(SCC(=O)Nc4cccc(C)c4C)ccc3n2)cc1 nan
16012637 39730 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 0 10 3.3 Cc1ccc2nc3c(cc(C#N)c(=O)n3-c3nnc(SCc4ccccc4)s3)c(=O)n2c1 nan
CHEMBL1476168 39730 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 0 10 3.3 Cc1ccc2nc3c(cc(C#N)c(=O)n3-c3nnc(SCc4ccccc4)s3)c(=O)n2c1 nan
16009819 39740 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 8 4.3 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1Cl nan
CHEMBL1476323 39740 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 8 4.3 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1Cl nan
16009801 39746 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)c(OC)c1 nan
CHEMBL1476410 39746 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)c(OC)c1 nan
15987507 39751 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 4 6.1 Cc1cc(C)c2oc(-c3ccc(Cl)c(NC(=O)c4cccs4)c3)nc2c1 nan
CHEMBL1476493 39751 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 4 6.1 Cc1cc(C)c2oc(-c3ccc(Cl)c(NC(=O)c4cccs4)c3)nc2c1 nan
16030393 39759 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 4 5.2 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCc3ccccc32)cc1 nan
CHEMBL1476572 39759 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 4 5.2 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCc3ccccc32)cc1 nan
16010862 39767 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 2.9 Cc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1C nan
CHEMBL1476637 39767 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 2.9 Cc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1C nan
4154280 39780 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 5 5.9 CCc1ccccc1NC(=O)C(CC)Sc1ncnc2c1sc1ccccc12 nan
CHEMBL1476806 39780 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 5 5.9 CCc1ccccc1NC(=O)C(CC)Sc1ncnc2c1sc1ccccc12 nan
7184887 39794 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 0 8 3.4 CC1CCN(c2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)CC1 nan
CHEMBL1476979 39794 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 0 8 3.4 CC1CCN(c2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)CC1 nan
666072 39896 8 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 1 6 4.6 CSc1ccc(-c2c(C#N)c(N)nc3c2c(C)nn3-c2ccccc2)cc1 nan
CHEMBL1477886 39896 8 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 1 6 4.6 CSc1ccc(-c2c(C#N)c(N)nc3c2c(C)nn3-c2ccccc2)cc1 nan
2810062 39911 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 2 1 6 2.9 Cc1csc2c(=O)sc(NC(=O)c3ccco3)nc12 nan
CHEMBL1478110 39911 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 2 1 6 2.9 Cc1csc2c(=O)sc(NC(=O)c3ccco3)nc12 nan
16014364 39943 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 4 4.8 Cc1ccc(CNC(=O)c2nc(SCc3ccc(F)cc3)ncc2Cl)cc1 nan
CHEMBL1478416 39943 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 4 4.8 Cc1ccc(CNC(=O)c2nc(SCc3ccc(F)cc3)ncc2Cl)cc1 nan
947086 39966 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 0 4 4.1 COc1ccc(-c2c(C#N)c(C)nc3c2C(=O)c2ccccc2-3)cc1 nan
CHEMBL1478573 39966 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 0 4 4.1 COc1ccc(-c2c(C#N)c(C)nc3c2C(=O)c2ccccc2-3)cc1 nan
15990421 39977 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 1 4 5.9 Cc1cc(Br)ccc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1478684 39977 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 1 4 5.9 Cc1cc(Br)ccc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
2150494 39989 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 7 3.8 COCCn1c(SCC(=O)Nc2ccc(C)cc2)nc2c(oc3ccccc32)c1=O nan
CHEMBL1478802 39989 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 7 3.8 COCCn1c(SCC(=O)Nc2ccc(C)cc2)nc2c(oc3ccccc32)c1=O nan
9267240 39997 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 O=C(Nc1ccc(Cl)cc1F)c1ccc(-n2cncn2)cc1 nan
CHEMBL1478883 39997 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 O=C(Nc1ccc(Cl)cc1F)c1ccc(-n2cncn2)cc1 nan
16015604 40037 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 6 6.3 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccc(C)cc3)on2)cc1 nan
CHEMBL1479260 40037 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 6 6.3 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccc(C)cc3)on2)cc1 nan
4050786 40109 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 7 2.8 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(NC(C)=O)ccc21 nan
CHEMBL1479784 40109 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 7 2.8 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(NC(C)=O)ccc21 nan
16009694 40111 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 8 4.6 COc1ccc(-c2nnn3c2nc(NCCc2ccc(OC)c(OC)c2)c2ccccc23)cc1 nan
CHEMBL1479788 40111 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 8 4.6 COc1ccc(-c2nnn3c2nc(NCCc2ccc(OC)c(OC)c2)c2ccccc23)cc1 nan
2140519 40272 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 3 6 1.2 COC(=O)CCC(=O)NC(=S)Nc1sc(C)c(C)c1C(N)=O nan
CHEMBL1481122 40272 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 3 6 1.2 COC(=O)CCC(=O)NC(=S)Nc1sc(C)c(C)c1C(N)=O nan
16189596 40285 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 4 4.5 CCN1CCCc2cc(CN(CCN3CCOCC3)C(S)=Nc3ccccc3C)ccc21 nan
CHEMBL1481195 40285 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 4 4.5 CCN1CCCc2cc(CN(CCN3CCOCC3)C(S)=Nc3ccccc3C)ccc21 nan
6324455 40369 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 1 4 3.1 CCN(CC)S(=O)(=O)c1ccc2nc(O)c3ccccc3c2c1 nan
CHEMBL1482015 40369 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 1 4 3.1 CCN(CC)S(=O)(=O)c1ccc2nc(O)c3ccccc3c2c1 nan
4898982 40394 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 5 2.9 COc1ccc2cc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)[nH]c2c1 nan
CHEMBL1482223 40394 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 5 2.9 COc1ccc2cc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)[nH]c2c1 nan
16194617 40404 9 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 6 4.4 CCOc1ncccc1C(=O)Nc1cccc(-c2nc3cccnc3s2)c1 nan
CHEMBL1482332 40404 9 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 6 4.4 CCOc1ncccc1C(=O)Nc1cccc(-c2nc3cccnc3s2)c1 nan
7598416 40508 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 2.6 Cc1cccc(Cn2cccc(C(=O)Nc3nnc(C)s3)c2=O)c1 nan
CHEMBL1483270 40508 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 2.6 Cc1cccc(Cn2cccc(C(=O)Nc3nnc(C)s3)c2=O)c1 nan
16033878 40520 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 6 4.0 Cc1c(Cl)cccc1Nc1nn2c(=O)c3ccccc3nc2s1 nan
CHEMBL1483384 40520 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 6 4.0 Cc1c(Cl)cccc1Nc1nn2c(=O)c3ccccc3nc2s1 nan
5033969 40564 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 4 3.0 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(Cl)c(S(=O)(=O)N(C)C)c2)c1C nan
CHEMBL1483695 40564 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 4 3.0 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(Cl)c(S(=O)(=O)N(C)C)c2)c1C nan
2346667 40574 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 6 0 5 2.8 COc1ccc(C(=O)COC(=O)c2ccc(N(C)C)cc2)cc1 nan
CHEMBL1483762 40574 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 6 0 5 2.8 COc1ccc(C(=O)COC(=O)c2ccc(N(C)C)cc2)cc1 nan
4199549 40595 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 9 0 6 4.9 CCOc1ccccc1C(=O)N1CCc2cc(OC)c(OC)cc2C1COc1ccc(OC)cc1 nan
CHEMBL1483991 40595 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 9 0 6 4.9 CCOc1ccccc1C(=O)N1CCc2cc(OC)c(OC)cc2C1COc1ccc(OC)cc1 nan
135399202 40660 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 5 3.1 NC1=C(c2nc3ccccc3s2)C(=O)CN1C1CCCCC1 nan
CHEMBL1484439 40660 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 5 3.1 NC1=C(c2nc3ccccc3s2)C(=O)CN1C1CCCCC1 nan
2377756 40696 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 6 3.4 O=C(O)c1cccnc1Sc1ncnc2sc3c(c12)CCC3 nan
CHEMBL1484807 40696 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 6 3.4 O=C(O)c1cccnc1Sc1ncnc2sc3c(c12)CCC3 nan
135410529 40735 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 6 4.7 CCS(=O)(=O)c1cccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c1 nan
CHEMBL1485170 40735 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 6 4.7 CCS(=O)(=O)c1cccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c1 nan
135521955 40774 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 2 7 4.7 Cc1cc(-n2c(SCC(=O)NCCC3=CCCCC3)nc3nnc(C)c-3c2N)ccc1Cl nan
CHEMBL1485562 40774 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 2 7 4.7 Cc1cc(-n2c(SCC(=O)NCCC3=CCCCC3)nc3nnc(C)c-3c2N)ccc1Cl nan
15989053 40786 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 8 1 8 4.0 Cc1cc(C)c(Cn2c(=O)n(CCCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1485622 40786 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 8 1 8 4.0 Cc1cc(C)c(Cn2c(=O)n(CCCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c(C)c1 nan
4277738 40798 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 3 4.8 Sc1nc(-c2ccc(Br)cc2)cn1CCc1ccccc1 nan
CHEMBL1485734 40798 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 3 4.8 Sc1nc(-c2ccc(Br)cc2)cn1CCc1ccccc1 nan
16012072 40834 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 11 1 6 3.8 CCCCN(C)CCCNC(=O)Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O nan
CHEMBL1486036 40834 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 11 1 6 3.8 CCCCN(C)CCCNC(=O)Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O nan
1273744 40864 11 None -6 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 7 3.8 Cc1cc(C)c(C#N)c(SCC(=O)Nc2nnc(-c3ccccc3)s2)n1 nan
CHEMBL1486391 40864 11 None -6 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 7 3.8 Cc1cc(C)c(C#N)c(SCC(=O)Nc2nnc(-c3ccccc3)s2)n1 nan
16021806 40887 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 4 5.1 CSc1ncc(C(=O)Nc2ccccc2C(F)(F)F)c(-c2ccccc2)n1 nan
CHEMBL1486543 40887 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 4 5.1 CSc1ncc(C(=O)Nc2ccccc2C(F)(F)F)c(-c2ccccc2)n1 nan
5339079 40916 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 4 4.4 Cc1nc(-c2ccccc2)nc2nc(-c3ccccc3)cc(O)c12 nan
CHEMBL1486764 40916 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 4 4.4 Cc1nc(-c2ccccc2)nc2nc(-c3ccccc3)cc(O)c12 nan
702036 40993 13 None -19 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 1 0 5 4.2 N#Cc1c2c(c(-n3cnc4ccccc43)n3c1nc1ccccc13)CCC2 nan
CHEMBL1487421 40993 13 None -19 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 1 0 5 4.2 N#Cc1c2c(c(-n3cnc4ccccc43)n3c1nc1ccccc13)CCC2 nan
15989752 41013 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 3.9 Cc1ccc2nc(NCCc3ccc(Cl)cc3)c3nncn3c2c1 nan
CHEMBL1487625 41013 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 3.9 Cc1ccc2nc(NCCc3ccc(Cl)cc3)c3nncn3c2c1 nan
16008663 41026 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 8 1.6 COC(=O)c1ccc(NC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1487699 41026 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 8 1.6 COC(=O)c1ccc(NC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 nan
16025367 41122 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 570 7 1 7 5.4 COc1ccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2F)S3(=O)=O)cc1 nan
CHEMBL1488348 41122 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 570 7 1 7 5.4 COc1ccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2F)S3(=O)=O)cc1 nan
4611609 41128 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 3 6.2 CCc1ccc(OCC(=O)Nc2ccc3c(c2)c2ccccc2n3CC)c(Br)c1 nan
CHEMBL1488388 41128 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 3 6.2 CCc1ccc(OCC(=O)Nc2ccc3c(c2)c2ccccc2n3CC)c(Br)c1 nan
1726407 41149 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 4 6.4 CCOc1cccc(C(=O)Nc2ccc3oc(-c4ccc(C(C)(C)C)cc4)nc3c2)c1 nan
CHEMBL1488581 41149 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 4 6.4 CCOc1cccc(C(=O)Nc2ccc3oc(-c4ccc(C(C)(C)C)cc4)nc3c2)c1 nan
16030737 41185 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 10 2.0 Cc1ccc(-c2nc(SCC(=O)Nc3cc(C)on3)c3c(=O)n(C)c(=O)n(C)c3n2)cc1 nan
CHEMBL1488787 41185 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 10 2.0 Cc1ccc(-c2nc(SCC(=O)Nc3cc(C)on3)c3c(=O)n(C)c(=O)n(C)c3n2)cc1 nan
824820 41234 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 5 3.1 Cc1ccc(-n2c(N)c(C#N)c(-c3ccccc3)c(C#N)c2=O)cc1 nan
CHEMBL1489157 41234 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 5 3.1 Cc1ccc(-n2c(N)c(C#N)c(-c3ccccc3)c(C#N)c2=O)cc1 nan
2036296 41275 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 0 6 4.0 CCCCn1c(-c2cccs2)nc2oc3ccccc3c(=O)c2c1=O nan
CHEMBL1489469 41275 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 0 6 4.0 CCCCn1c(-c2cccs2)nc2oc3ccccc3c(=O)c2c1=O nan
3448820 41331 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 0 4 4.8 COc1cc2c(cc1OC)C(COc1ccc(F)cc1)N(C(=O)c1ccccc1F)CC2 nan
CHEMBL1489934 41331 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 0 4 4.8 COc1cc2c(cc1OC)C(COc1ccc(F)cc1)N(C(=O)c1ccccc1F)CC2 nan
655760 41406 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 4 3.0 Cc1ccc(C)c(NC(=O)Cn2nc(C)c3ccccc3c2=O)c1 nan
CHEMBL1490512 41406 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 4 3.0 Cc1ccc(C)c(NC(=O)Cn2nc(C)c3ccccc3c2=O)c1 nan
16007588 41438 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 5 4.1 CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)NCCc1ccc(Cl)cc1)cn2C nan
CHEMBL1490705 41438 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 5 4.1 CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)NCCc1ccc(Cl)cc1)cn2C nan
1483825 41445 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 4 4.3 FC(F)(F)c1cnc(-c2cnc(-c3cccnc3)nc2)c(Cl)c1 nan
CHEMBL1490743 41445 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 4 4.3 FC(F)(F)c1cnc(-c2cnc(-c3cccnc3)nc2)c(Cl)c1 nan
16194118 41471 8 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 8 2.0 CCOC(=O)c1ccc(NC(=S)N2CCN(c3ccc(N4CCOCC4)nn3)CC2)cc1 nan
CHEMBL1490926 41471 8 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 8 2.0 CCOC(=O)c1ccc(NC(=S)N2CCN(c3ccc(N4CCOCC4)nn3)CC2)cc1 nan
4578555 41492 17 None -7 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 3.9 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCCC1 nan
CHEMBL1491054 41492 17 None -7 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 3.9 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCCC1 nan
1147591 41553 19 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 3.0 COc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1 nan
CHEMBL1491533 41553 19 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 3.0 COc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1 nan
761949 41686 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 4 3.7 CC(=O)c1cnc2cc(-c3cccc(Br)c3)nn2c1C nan
CHEMBL1492474 41686 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 4 3.7 CC(=O)c1cnc2cc(-c3cccc(Br)c3)nn2c1C nan
16031672 41735 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 2 4 2.8 O=C(Nc1ccc(F)cc1F)C1CCN(S(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)CC1 nan
CHEMBL1492791 41735 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 2 4 2.8 O=C(Nc1ccc(F)cc1F)C1CCN(S(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)CC1 nan
3496289 41768 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 11 2 7 3.7 CCOc1cc2[nH]c(=S)n(Cc3ccc(C(=O)NCCCOC)cc3)c(=O)c2cc1OCC nan
CHEMBL1493174 41768 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 11 2 7 3.7 CCOc1cc2[nH]c(=S)n(Cc3ccc(C(=O)NCCCOC)cc3)c(=O)c2cc1OCC nan
16033055 41781 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 10 0 11 3.4 CCOc1ccc(C(=O)Cn2c(=O)n3nc(CCn4nc(C)cc4C)nc3c3cc(OC)c(OC)cc32)cc1 nan
CHEMBL1493282 41781 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 10 0 11 3.4 CCOc1ccc(C(=O)Cn2c(=O)n3nc(CCn4nc(C)cc4C)nc3c3cc(OC)c(OC)cc32)cc1 nan
6324582 41835 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 2 3 3.7 Cc1ccc2cc(CCNC(=O)CC(C)(C)C)c(O)nc2c1C nan
CHEMBL1493825 41835 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 2 3 3.7 Cc1ccc2cc(CCNC(=O)CC(C)(C)C)c(O)nc2c1C nan
2337492 41905 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 5 5.2 CCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c1ccc(C)cc1)c1ccccc12 nan
CHEMBL1494522 41905 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 5 5.2 CCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c1ccc(C)cc1)c1ccccc12 nan
16030367 41974 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 5.5 CCc1ccccc1NC(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1 nan
CHEMBL1495193 41974 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 5.5 CCc1ccccc1NC(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1 nan
659270 41980 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 1 8 2.7 CCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OC)cc2)c1C#N nan
CHEMBL1495223 41980 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 1 8 2.7 CCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OC)cc2)c1C#N nan
1473491 41981 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 0 4 4.3 O=C1c2ccccc2C(=O)N1CCc1csc(-c2cccc(Cl)c2)n1 nan
CHEMBL1495238 41981 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 0 4 4.3 O=C1c2ccccc2C(=O)N1CCc1csc(-c2cccc(Cl)c2)n1 nan
803577 42004 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 6 2.6 CC(=O)c1sc(NC(=O)c2ccc3c(c2)OCO3)nc1C nan
CHEMBL1495561 42004 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 6 2.6 CC(=O)c1sc(NC(=O)c2ccc3c(c2)OCO3)nc1C nan
16015766 42011 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 2 2 4.9 CC(C)CC(=O)Nc1ccc(Cl)c(-c2nc3ccccc3[nH]2)c1 nan
CHEMBL1495596 42011 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 2 2 4.9 CC(C)CC(=O)Nc1ccc(Cl)c(-c2nc3ccccc3[nH]2)c1 nan
1394903 42021 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 6 0 5 4.9 O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccn(Cc2ccccc2)c1)c1ccc(Br)cc1 nan
CHEMBL1495702 42021 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 6 0 5 4.9 O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccn(Cc2ccccc2)c1)c1ccc(Br)cc1 nan
9550975 42104 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 6 4.1 COc1ccccc1CNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1496499 42104 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 6 4.1 COc1ccccc1CNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C nan
7190533 42141 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 6 3.8 Cc1ccccc1CSc1ccc2nnc(-c3ccccn3)n2n1 nan
CHEMBL1496795 42141 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 6 3.8 Cc1ccccc1CSc1ccc2nnc(-c3ccccn3)n2n1 nan
22548523 42154 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 2.8 CN(Cc1ccccc1)S(=O)(=O)c1ccc2nc(O)ccc2c1 nan
CHEMBL1496881 42154 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 2.8 CN(Cc1ccccc1)S(=O)(=O)c1ccc2nc(O)ccc2c1 nan
16030464 42169 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 2 4 5.1 COc1ccccc1C(=O)Nc1ccccc1SCc1cc(=O)c2ccccc2[nH]1 nan
CHEMBL1497018 42169 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 2 4 5.1 COc1ccccc1C(=O)Nc1ccccc1SCc1cc(=O)c2ccccc2[nH]1 nan
3282397 42199 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 3.8 CCOc1ccc(-n2nc(C(=O)NC3CCCCC3)c3ccccc3c2=O)cc1 nan
CHEMBL1497244 42199 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 3.8 CCOc1ccc(-n2nc(C(=O)NC3CCCCC3)c3ccccc3c2=O)cc1 nan
2190255 42205 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 3 6 -0.1 CCN1C(=O)/C(=C/Nc2ccc(S(N)(=O)=O)cc2)C(=O)NC1=S nan
CHEMBL1497307 42205 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 3 6 -0.1 CCN1C(=O)/C(=C/Nc2ccc(S(N)(=O)=O)cc2)C(=O)NC1=S nan
860457 42276 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 0 6 2.6 CSc1nnc(-c2ccc(S(=O)(=O)N3CCCCC3)cc2)o1 nan
CHEMBL1497958 42276 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 0 6 2.6 CSc1nnc(-c2ccc(S(=O)(=O)N3CCCCC3)cc2)o1 nan
2815318 42355 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 7 2.2 CCOC(=O)Cn1cnc2c(sc3nc(C)cc(C)c32)c1=O nan
CHEMBL1498797 42355 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 7 2.2 CCOC(=O)Cn1cnc2c(sc3nc(C)cc(C)c32)c1=O nan
2126242 42359 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 5 4.3 COc1ccc2c(C)cc(SCC(=O)Nc3cccnc3Cl)nc2c1 nan
CHEMBL1498813 42359 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 5 4.3 COc1ccc2c(C)cc(SCC(=O)Nc3cccnc3Cl)nc2c1 nan
1105537 42448 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 8 1 6 3.2 CCOC(=O)/C(C#N)=C/c1ccc(OCC(=O)Nc2ccccc2)c(OC)c1 nan
CHEMBL1499500 42448 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 8 1 6 3.2 CCOC(=O)/C(C#N)=C/c1ccc(OCC(=O)Nc2ccccc2)c(OC)c1 nan
649649 42461 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 1 6 2.0 Cc1ccnc(N2CCC(C(=O)NCc3ccc4c(c3)OCO4)CC2)n1 nan
CHEMBL1499616 42461 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 1 6 2.0 Cc1ccnc(N2CCC(C(=O)NCc3ccc4c(c3)OCO4)CC2)n1 nan
866361 42462 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 5 2.8 O=c1c2ccccc2[nH]c(=S)n1Cc1ccc2c(c1)OCO2 nan
CHEMBL1499629 42462 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 5 2.8 O=c1c2ccccc2[nH]c(=S)n1Cc1ccc2c(c1)OCO2 nan
2764824 42488 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 2 2 2.8 CNC(=O)c1cc(C(=O)c2ccc(C(F)(F)F)cc2F)c[nH]1 nan
CHEMBL1499851 42488 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 2 2 2.8 CNC(=O)c1cc(C(=O)c2ccc(C(F)(F)F)cc2F)c[nH]1 nan
852955 42523 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 4 5.0 Cc1sc2nc(Cc3ccccc3)nc(O)c2c1-c1ccccc1 nan
CHEMBL1500159 42523 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 4 5.0 Cc1sc2nc(Cc3ccccc3)nc(O)c2c1-c1ccccc1 nan
135415434 42679 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 1 7 2.3 Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3nc(O)c4ccccc4n3)CC2)cc1 nan
CHEMBL1501602 42679 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 1 7 2.3 Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3nc(O)c4ccccc4n3)CC2)cc1 nan
54676936 42700 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 2 4 3.0 O=C(Nc1cccc(F)c1)c1c(O)c2cccc3c2n(c1=O)CCC3 nan
CHEMBL1501763 42700 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 2 4 3.0 O=C(Nc1cccc(F)c1)c1c(O)c2cccc3c2n(c1=O)CCC3 nan
1176241 42757 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 8 1 6 4.5 CCOc1ccc2nc(SCC(=O)Nc3ccc(S(=O)(=O)N4CCCC4)cc3)c(C)cc2c1 nan
CHEMBL1502202 42757 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 8 1 6 4.5 CCOc1ccc2nc(SCC(=O)Nc3ccc(S(=O)(=O)N4CCCC4)cc3)c(C)cc2c1 nan
734457 42856 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 257 3 1 5 2.6 COC(=O)c1ccc(Nc2nc(C)cc(C)n2)cc1 nan
CHEMBL1503104 42856 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 257 3 1 5 2.6 COC(=O)c1ccc(Nc2nc(C)cc(C)n2)cc1 nan
2515869 42880 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 5 2.9 CCC(=O)c1ccc(OCC(=O)c2ccc3c(c2)NC(=O)CO3)cc1 nan
CHEMBL1503299 42880 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 5 2.9 CCC(=O)c1ccc(OCC(=O)c2ccc3c(c2)NC(=O)CO3)cc1 nan
5310469 42910 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 0 8 3.3 COc1ccc(-c2nnc3ccc(SCC(=O)N4CCCCCC4)nn23)cc1OC nan
CHEMBL1503498 42910 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 0 8 3.3 COc1ccc(-c2nnc3ccc(SCC(=O)N4CCCCCC4)nn23)cc1OC nan
3574258 42918 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccc(Cl)cc1 nan
CHEMBL1503560 42918 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccc(Cl)cc1 nan
1859366 42923 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 4 5.0 Cc1ccc(S(=O)(=O)N(Cc2cc3ccc(C)cc3nc2O)c2ccccc2)cc1 nan
CHEMBL1503583 42923 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 4 5.0 Cc1ccc(S(=O)(=O)N(Cc2cc3ccc(C)cc3nc2O)c2ccccc2)cc1 nan
664334 43028 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 0 4 4.2 O=C1CC(c2ccc(F)cc2)Cc2nc(N3CCc4ccccc43)ncc21 nan
CHEMBL1504653 43028 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 0 4 4.2 O=C1CC(c2ccc(F)cc2)Cc2nc(N3CCc4ccccc43)ncc21 nan
2980439 43087 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 7 2 4 3.2 CCc1ccc(N2CCN(CCNC(=O)Nc3ccc(OC)cc3)CC2)cc1 nan
CHEMBL1505203 43087 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 7 2 4 3.2 CCc1ccc(N2CCN(CCNC(=O)Nc3ccc(OC)cc3)CC2)cc1 nan
661657 43097 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 0 7 3.3 O=C1c2ccccc2C(=O)N1Cc1nn2c(-c3ccc(Cl)cc3)nnc2s1 nan
CHEMBL1505268 43097 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 0 7 3.3 O=C1c2ccccc2C(=O)N1Cc1nn2c(-c3ccc(Cl)cc3)nnc2s1 nan
12006071 43115 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 0 6 4.5 O=C(CSc1ccc2nnc(-c3ccc(Cl)cc3)n2n1)N1CCCc2ccccc21 nan
CHEMBL1505466 43115 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 0 6 4.5 O=C(CSc1ccc2nnc(-c3ccc(Cl)cc3)n2n1)N1CCCc2ccccc21 nan
834457 43179 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 2 3 2.7 NS(=O)(=O)c1ccc(NCc2c(F)cccc2Cl)cc1 nan
CHEMBL1505860 43179 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 2 3 2.7 NS(=O)(=O)c1ccc(NCc2c(F)cccc2Cl)cc1 nan
1804684 43185 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 5 3.8 COCc1cc(C)nc(SCC(=O)Nc2cccc(C)c2C)c1C#N nan
CHEMBL1505914 43185 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 5 3.8 COCc1cc(C)nc(SCC(=O)Nc2cccc(C)c2C)c1C#N nan
3882765 43214 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 2 1 3.9 Cc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3)cc2c1 nan
CHEMBL1506222 43214 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 2 1 3.9 Cc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3)cc2c1 nan
3795359 43253 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 6 3.8 CCC(C)c1ccc(-n2c(=O)c3ccccc3n3c(S)nnc23)cc1 nan
CHEMBL1506487 43253 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 6 3.8 CCC(C)c1ccc(-n2c(=O)c3ccccc3n3c(S)nnc23)cc1 nan
4118928 43258 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 7 2 5 2.1 CCCCOCCCN1C(C)=CC(=C2C(=O)NC(=S)NC2=O)C=C1C nan
CHEMBL1506535 43258 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 7 2 5 2.1 CCCCOCCCN1C(C)=CC(=C2C(=O)NC(=S)NC2=O)C=C1C nan
1078308 43314 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.4 COc1ccccc1NC(=O)c1sc2ncn(Cc3ccccc3C)c(=O)c2c1C nan
CHEMBL1507058 43314 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.4 COc1ccccc1NC(=O)c1sc2ncn(Cc3ccccc3C)c(=O)c2c1C nan
1390207 43322 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 0 5 4.8 O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccn(Cc2ccccc2)c1)c1ccc(Cl)cc1 nan
CHEMBL1507117 43322 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 0 5 4.8 O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccn(Cc2ccccc2)c1)c1ccc(Cl)cc1 nan
9550860 43340 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 3 2.0 Cc1ccc(OC(=O)c2ccccc2P(=O)(O)O)cc1 nan
CHEMBL1507343 43340 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 3 2.0 Cc1ccc(OC(=O)c2ccccc2P(=O)(O)O)cc1 nan
2810073 43352 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 1 6 3.3 Cc1csc2c(=O)sc(NC(=O)c3cccs3)nc12 nan
CHEMBL1507430 43352 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 1 6 3.3 Cc1csc2c(=O)sc(NC(=O)c3cccs3)nc12 nan
20874463 43417 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 5 4.1 Cc1ccc(-c2nnn3c2nc(NC(C)C)c2ccccc23)cc1 nan
CHEMBL1507945 43417 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 5 4.1 Cc1ccc(-c2nnn3c2nc(NC(C)C)c2ccccc23)cc1 nan
5875901 43436 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 4 3.8 CCOC(=O)CN1C(=O)/C(=C/c2cccc(Br)c2)Oc2ccccc21 nan
CHEMBL1508095 43436 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 4 3.8 CCOC(=O)CN1C(=O)/C(=C/c2cccc(Br)c2)Oc2ccccc21 nan
649082 43467 2 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 2 7 2.6 O=C(Cn1nnc(-c2ccccc2NC(=O)c2ccco2)n1)NC1CCCCC1 nan
CHEMBL1508376 43467 2 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 2 7 2.6 O=C(Cn1nnc(-c2ccccc2NC(=O)c2ccco2)n1)NC1CCCCC1 nan
1735895 43770 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 2 7 3.2 CCc1ccc(OCC(=O)NNC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 nan
CHEMBL1511120 43770 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 2 7 3.2 CCc1ccc(OCC(=O)NNC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 nan
1186303 43795 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 2 6 3.3 CN(C)c1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3nccs3)cc2)cc1 nan
CHEMBL1511271 43795 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 2 6 3.3 CN(C)c1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3nccs3)cc2)cc1 nan
2815635 43831 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 2 4 5.7 O=C(Nc1ccccc1)Nc1sccc1-c1nc2ccccc2s1 nan
CHEMBL1511507 43831 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 2 4 5.7 O=C(Nc1ccccc1)Nc1sccc1-c1nc2ccccc2s1 nan
661880 43833 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 1 0 6 2.3 N#CCc1nc2c3c4c(sc3ncn2n1)CCCC4 nan
CHEMBL1511519 43833 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 1 0 6 2.3 N#CCc1nc2c3c4c(sc3ncn2n1)CCCC4 nan
4604131 43876 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 7 3.9 COc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3ccsc3c2=O)cc1 nan
CHEMBL1512120 43876 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 7 3.9 COc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3ccsc3c2=O)cc1 nan
16027453 43908 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 8 3.7 COc1ccccc1C(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2c(C)csc2n1 nan
CHEMBL1512551 43908 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 8 3.7 COc1ccccc1C(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2c(C)csc2n1 nan
16018474 43910 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 4 5.8 CCc1ccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCCCC4)ccc23)cc1 nan
CHEMBL1512597 43910 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 4 5.8 CCc1ccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCCCC4)ccc23)cc1 nan
16030606 43912 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.1 Cc1cccc(C(=O)Nc2cccc(OCc3cc(=O)n4cccc(C)c4n3)c2)c1 nan
CHEMBL1512611 43912 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.1 Cc1cccc(C(=O)Nc2cccc(OCc3cc(=O)n4cccc(C)c4n3)c2)c1 nan
16030447 43913 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.5 Cc1ccc2nc(COc3cccc(NC(=O)c4ccccc4Cl)c3)cc(=O)n2c1 nan
CHEMBL1512613 43913 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.5 Cc1ccc2nc(COc3cccc(NC(=O)c4ccccc4Cl)c3)cc(=O)n2c1 nan
7245878 43920 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 0 6 2.6 COc1ccc(S(=O)(=O)c2cc3cc(OC)ccc3oc2=O)cc1 nan
CHEMBL1512705 43920 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 0 6 2.6 COc1ccc(S(=O)(=O)c2cc3cc(OC)ccc3oc2=O)cc1 nan
16020157 43940 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 0 9 3.6 CCOC(=O)CSc1nc2cc(OC)c(OC)cc2c2nc(-c3ccccc3)nn12 nan
CHEMBL1512982 43940 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 0 9 3.6 CCOC(=O)CSc1nc2cc(OC)c(OC)cc2c2nc(-c3ccccc3)nn12 nan
16023839 43941 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 3 0 6 4.0 CN1CCN(C(=O)c2cnn(-c3cccc(Cl)c3)c2C2CCN(C(=O)OC(C)(C)C)CC2)CC1 nan
CHEMBL1513006 43941 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 3 0 6 4.0 CN1CCN(C(=O)c2cnn(-c3cccc(Cl)c3)c2C2CCN(C(=O)OC(C)(C)C)CC2)CC1 nan
3402023 43943 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 8 2 5 5.4 COc1ccc(CNC(=O)c2ccc(Sc3ccc(Cl)cc3)c(NC(C)=O)c2)c(OC)c1 nan
CHEMBL1513023 43943 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 8 2 5 5.4 COc1ccc(CNC(=O)c2ccc(Sc3ccc(Cl)cc3)c(NC(C)=O)c2)c(OC)c1 nan
16014785 43944 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 2 6 4.5 COC(=O)c1ccc(NC(=O)CSc2nc(C)cc(C)c2C(=O)Nc2ccccc2)cc1 nan
CHEMBL1513057 43944 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 2 6 4.5 COC(=O)c1ccc(NC(=O)CSc2nc(C)cc(C)c2C(=O)Nc2ccccc2)cc1 nan
16021019 43946 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 5 6.0 O=C(NC1CCCCC1)c1ccc(CSc2nc3cccnc3n2Cc2ccc(F)cc2)cc1 nan
CHEMBL1513070 43946 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 5 6.0 O=C(NC1CCCCC1)c1ccc(CSc2nc3cccnc3n2Cc2ccc(F)cc2)cc1 nan
16008530 43952 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 5 6.0 CSc1ccc(CCNC(=O)CCc2c(C)nc3c(c(C)nn3-c3ccc(C)c(C)c3)c2C)cc1 nan
CHEMBL1513168 43952 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 5 6.0 CSc1ccc(CCNC(=O)CCc2c(C)nc3c(c(C)nn3-c3ccc(C)c(C)c3)c2C)cc1 nan
16018739 43963 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 5 3.0 O=C(CCn1c(=O)c2cccn2c2cccnc21)NCc1ccc(Cl)cc1 nan
CHEMBL1513371 43963 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 5 3.0 O=C(CCn1c(=O)c2cccn2c2cccnc21)NCc1ccc(Cl)cc1 nan
16030719 43966 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 9 2.0 Cc1cccc(-c2nc(SCC(=O)NCc3ccco3)c3c(=O)n(C)c(=O)n(C)c3n2)c1 nan
CHEMBL1513435 43966 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 9 2.0 Cc1cccc(-c2nc(SCC(=O)NCc3ccco3)c3c(=O)n(C)c(=O)n(C)c3n2)c1 nan
16025371 43968 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 568 6 1 6 6.0 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2F)S3(=O)=O)c1 nan
CHEMBL1513466 43968 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 568 6 1 6 6.0 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2F)S3(=O)=O)c1 nan
16026779 43972 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 8 2.8 O=C(CNC(=O)c1ccc(F)cc1)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
CHEMBL1513507 43972 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 8 2.8 O=C(CNC(=O)c1ccc(F)cc1)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
16024940 43974 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 4 4.9 O=C(NCCc1ccccc1Cl)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1513535 43974 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 4 4.9 O=C(NCCc1ccccc1Cl)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
1316309 43986 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.6 Cc1ccc2oc(-c3ccc(Cl)c(NC(=O)Cc4ccccc4)c3)nc2c1 nan
CHEMBL1513652 43986 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.6 Cc1ccc2oc(-c3ccc(Cl)c(NC(=O)Cc4ccccc4)c3)nc2c1 nan
16025593 44001 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 3 0 8 3.9 Cc1c(-c2nc(-c3ccc4c(c3)OCO4)no2)nnn1-c1ccc(Br)cc1F nan
CHEMBL1514000 44001 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 3 0 8 3.9 Cc1c(-c2nc(-c3ccc4c(c3)OCO4)no2)nnn1-c1ccc(Br)cc1F nan
15989077 44016 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 10 1 8 4.8 Cc1cc(C)c(Cn2c(=O)n(CCCCCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1514246 44016 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 10 1 8 4.8 Cc1cc(C)c(Cn2c(=O)n(CCCCCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c(C)c1 nan
2689697 44021 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 5 3.2 COc1ccc(C(=O)OCC(=O)c2c[nH]c3ccccc23)cc1OC nan
CHEMBL1514340 44021 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 5 3.2 COc1ccc(C(=O)OCC(=O)c2c[nH]c3ccccc23)cc1OC nan
24982480 44034 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 5 2.3 CCN(Cc1ccccc1)C(=O)Cc1ccc(OC)c(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1514540 44034 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 5 2.3 CCN(Cc1ccccc1)C(=O)Cc1ccc(OC)c(S(=O)(=O)N2CCOCC2)c1 nan
16015735 44059 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 3 3 9 2.5 COC(=O)c1c(C)sc(-c2c(-c3ccc4c(c3)OCCO4)[nH]c3c2c(=O)[nH]c(=O)n3C)c1O nan
CHEMBL1514818 44059 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 3 3 9 2.5 COC(=O)c1c(C)sc(-c2c(-c3ccc4c(c3)OCCO4)[nH]c3c2c(=O)[nH]c(=O)n3C)c1O nan
16022151 44063 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 0 6 2.5 COc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1C)n2C nan
CHEMBL1514879 44063 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 0 6 2.5 COc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1C)n2C nan
16009667 44071 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 5 4.5 O=c1c2sc3ccccc3c2n(Cc2ccccc2)c(=O)n1Cc1ccccc1 nan
CHEMBL1515036 44071 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 5 4.5 O=c1c2sc3ccccc3c2n(Cc2ccccc2)c(=O)n1Cc1ccccc1 nan
5167801 44074 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 3 5.0 O=C(NC1CCCCC1)c1cc(Nc2ccccc2)nc2ccccc12 nan
CHEMBL1515050 44074 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 3 5.0 O=C(NC1CCCCC1)c1cc(Nc2ccccc2)nc2ccccc12 nan
16030854 44076 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 2 4 5.0 CC(NC(=O)c1ccc(NC(=O)c2nsc3ccccc23)cc1)c1ccccc1 nan
CHEMBL1515130 44076 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 2 4 5.0 CC(NC(=O)c1ccc(NC(=O)c2nsc3ccccc23)cc1)c1ccccc1 nan
135416423 44097 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 2 4 4.7 CCc1ccc2oc(-c3cc(NC(=O)C(C)C)cc(C)c3O)nc2c1 nan
CHEMBL1515394 44097 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 2 4 4.7 CCc1ccc2oc(-c3cc(NC(=O)C(C)C)cc(C)c3O)nc2c1 nan
8057488 44119 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 4 5.4 Cc1cc2nc(-c3ccc(OCc4ccccc4F)cc3)cc(C(F)(F)F)n2n1 nan
CHEMBL1515771 44119 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 4 5.4 Cc1cc2nc(-c3ccc(OCc4ccccc4F)cc3)cc(C(F)(F)F)n2n1 nan
4154278 44121 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 5.2 Cc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1C nan
CHEMBL1515779 44121 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 5.2 Cc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1C nan
16017003 44147 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 4 4.5 CCOc1ccccc1NC(=O)C(=O)c1cc(C)n(-c2ccc(F)cc2)c1C nan
CHEMBL1516117 44147 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 4 4.5 CCOc1ccccc1NC(=O)C(=O)c1cc(C)n(-c2ccc(F)cc2)c1C nan
7343169 44158 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 5 4.9 CCOC(=O)c1cnc2cc(-c3ccc(Cl)cc3)nn2c1-c1ccccc1 nan
CHEMBL1516275 44158 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 5 4.9 CCOC(=O)c1cnc2cc(-c3ccc(Cl)cc3)nn2c1-c1ccccc1 nan
3586950 44166 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 6 4.6 O=C(CSc1nc2ccsc2c(=O)n1-c1ccc(Br)cc1)NCc1ccccc1 nan
CHEMBL1516478 44166 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 6 4.6 O=C(CSc1nc2ccsc2c(=O)n1-c1ccc(Br)cc1)NCc1ccccc1 nan
3206747 44307 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 COc1cccc(CC(=O)Nc2nc3c(s2)C(=O)CC(C)(C)C3)c1 nan
CHEMBL1517888 44307 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 COc1cccc(CC(=O)Nc2nc3c(s2)C(=O)CC(C)(C)C3)c1 nan
985821 44311 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 3 5.0 O=C(Nc1cc(F)cc(F)c1)c1sc(Cl)nc1-c1ccccc1 nan
CHEMBL1517907 44311 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 3 5.0 O=C(Nc1cc(F)cc(F)c1)c1sc(Cl)nc1-c1ccccc1 nan
1093907 44312 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 2 7 1.5 CNS(=O)(=O)c1ccc(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)cc1 nan
CHEMBL1517917 44312 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 2 7 1.5 CNS(=O)(=O)c1ccc(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)cc1 nan
15991337 44335 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 0 7 4.8 CCc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2nc(C)c(C(=O)OC)s2)cc1 nan
CHEMBL1518140 44335 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 0 7 4.8 CCc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2nc(C)c(C(=O)OC)s2)cc1 nan
16011836 44377 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 6 5.0 COc1ccc(CSc2nc3ccncc3n2CC(=O)Nc2cc(C)cc(C)c2)cc1 nan
CHEMBL1518592 44377 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 6 5.0 COc1ccc(CSc2nc3ccncc3n2CC(=O)Nc2cc(C)cc(C)c2)cc1 nan
1086869 44426 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 6 3.4 COc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)c(OC)c1 nan
CHEMBL1518977 44426 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 6 3.4 COc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)c(OC)c1 nan
730225 44439 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 3 2 6 2.2 N#CCc1c(C#N)c(N)nc(Nc2ccccc2)c1C#N nan
CHEMBL1519080 44439 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 3 2 6 2.2 N#CCc1c(C#N)c(N)nc(Nc2ccccc2)c1C#N nan
1008965 44451 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 4 6.1 CC(=O)c1cccc(NC(=O)c2cc(-c3ccc(Cl)s3)nc3ccccc23)c1 nan
CHEMBL1519196 44451 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 4 6.1 CC(=O)c1cccc(NC(=O)c2cc(-c3ccc(Cl)s3)nc3ccccc23)c1 nan
16025959 44534 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 8 1.6 O=C(NCCc1ccc(Cl)cc1)c1cnc2sc(N3CCOCC3)nn2c1=O nan
CHEMBL1519916 44534 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 8 1.6 O=C(NCCc1ccc(Cl)cc1)c1cnc2sc(N3CCOCC3)nn2c1=O nan
2740242 44541 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 2 2 4 3.1 Cc1noc(C(F)(F)F)c1C(=O)NNC(=O)c1cccc(C(F)(F)F)c1 nan
CHEMBL1519973 44541 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 2 2 4 3.1 Cc1noc(C(F)(F)F)c1C(=O)NNC(=O)c1cccc(C(F)(F)F)c1 nan
16020184 44634 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 8 0 9 5.3 COc1cc2nc(SCc3cccc(Cl)c3)n3nc(CCn4nc(C)cc4C)nc3c2cc1OC nan
CHEMBL1520786 44634 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 8 0 9 5.3 COc1cc2nc(SCc3cccc(Cl)c3)n3nc(CCn4nc(C)cc4C)nc3c2cc1OC nan
15989989 44637 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 8 2 9 3.4 COc1ccc(CCNC(=O)c2ccc(Nc3nc4ccccc4n4nnnc34)cc2)cc1OC nan
CHEMBL1520796 44637 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 8 2 9 3.4 COc1ccc(CCNC(=O)c2ccc(Nc3nc4ccccc4n4nnnc34)cc2)cc1OC nan
742057 44678 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 6 3.1 O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)c1ccco1 nan
CHEMBL1521136 44678 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 6 3.1 O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)c1ccco1 nan
16026879 44706 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 7 1 6 4.4 COc1ccc(Cn2ccc3nc(C)c(C(=O)NCc4ccc(SC)cc4)cc3c2=O)cc1 nan
CHEMBL1521365 44706 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 7 1 6 4.4 COc1ccc(Cn2ccc3nc(C)c(C(=O)NCc4ccc(SC)cc4)cc3c2=O)cc1 nan
1164118 44719 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 0 7 3.4 COc1ccc(-c2nnc(SCC(=O)N3CCc4ccccc43)o2)cc1OC nan
CHEMBL1521488 44719 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 0 7 3.4 COc1ccc(-c2nnc(SCC(=O)N3CCc4ccccc43)o2)cc1OC nan
3146504 44774 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 1 6 2.9 CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)nc1C nan
CHEMBL1521972 44774 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 1 6 2.9 CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)nc1C nan
16021952 44806 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 7 1 7 3.9 CCc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3c2c2cc(OC)ccc2n3C)c1 nan
CHEMBL1522220 44806 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 7 1 7 3.9 CCc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3c2c2cc(OC)ccc2n3C)c1 nan
4090626 44858 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 2 4 5.8 CCOc1ccc(NC(=O)c2c(NC(=O)Cc3ccccc3)sc3c2CCCCC3)cc1 nan
CHEMBL1522769 44858 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 2 4 5.8 CCOc1ccc(NC(=O)c2c(NC(=O)Cc3ccccc3)sc3c2CCCCC3)cc1 nan
3148294 44864 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 6 4.1 CC(C)CNC(=O)CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)n1 nan
CHEMBL1522819 44864 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 6 4.1 CC(C)CNC(=O)CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)n1 nan
16030650 44888 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 5 0 8 3.0 O=c1cc(CN2CCN(S(=O)(=O)c3ccccc3)CC2)nc2sc(-c3ccccc3Cl)nn12 nan
CHEMBL1522977 44888 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 5 0 8 3.0 O=c1cc(CN2CCN(S(=O)(=O)c3ccccc3)CC2)nc2sc(-c3ccccc3Cl)nn12 nan
16026964 44930 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 9 3.1 O=C(COc1ccccc1F)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
CHEMBL1523393 44930 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 9 3.1 O=C(COc1ccccc1F)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
16027395 44954 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 10 3.4 CCOCCc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)c3cccs3)nc2s1 nan
CHEMBL1523585 44954 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 10 3.4 CCOCCc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)c3cccs3)nc2s1 nan
2465708 44963 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 6 1 9 4.8 COc1ccccc1-n1c(=O)c(C#N)c(-c2ccc([N+](=O)[O-])cc2)c2cc(C(=O)c3ccccc3O)cnc21 nan
CHEMBL1523696 44963 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 6 1 9 4.8 COc1ccccc1-n1c(=O)c(C#N)c(-c2ccc([N+](=O)[O-])cc2)c2cc(C(=O)c3ccccc3O)cnc21 nan
1465904 44980 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 1 7 4.8 CCc1nnc(NC(=O)CSc2nc(C3CCCCC3)nc3ccccc23)s1 nan
CHEMBL1523892 44980 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 1 7 4.8 CCc1nnc(NC(=O)CSc2nc(C3CCCCC3)nc3ccccc23)s1 nan
7422674 44981 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 3 4.2 O=C(Nc1ccccc1C(F)(F)F)c1cccn(Cc2ccccc2)c1=O nan
CHEMBL1523907 44981 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 3 4.2 O=C(Nc1ccccc1C(F)(F)F)c1cccn(Cc2ccccc2)c1=O nan
15989150 45025 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 9 1 6 3.6 COc1ccccc1CNC(=O)CCCn1c(=O)c2ccccc2n(Cc2ccc(C)cc2)c1=O nan
CHEMBL1524350 45025 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 9 1 6 3.6 COc1ccccc1CNC(=O)CCCn1c(=O)c2ccccc2n(Cc2ccc(C)cc2)c1=O nan
2548636 45109 5 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 3 7 2.5 Cc1nc(SCC(=O)Nc2cc(C(N)=O)cc(C(N)=O)c2)c2c(C)c(C)sc2n1 nan
CHEMBL1525189 45109 5 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 3 7 2.5 Cc1nc(SCC(=O)Nc2cc(C(N)=O)cc(C(N)=O)c2)c2c(C)c(C)sc2n1 nan
15989883 45113 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 1 3 5.4 Cc1c(C(=O)OC2CCCCC2)[nH]c2c1C(=O)CC(c1ccccc1Cl)C2 nan
CHEMBL1525262 45113 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 1 3 5.4 Cc1c(C(=O)OC2CCCCC2)[nH]c2c1C(=O)CC(c1ccccc1Cl)C2 nan
1186420 45156 10 None -31 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 7 3.8 Clc1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 nan
CHEMBL1525610 45156 10 None -31 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 7 3.8 Clc1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 nan
4154665 45160 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 10 2 7 3.3 CCOc1cc2[nH]c(=S)n(Cc3ccc(C(=O)NCCOC)cc3)c(=O)c2cc1OCC nan
CHEMBL1525634 45160 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 10 2 7 3.3 CCOc1cc2[nH]c(=S)n(Cc3ccc(C(=O)NCCOC)cc3)c(=O)c2cc1OCC nan
135460528 45215 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 3 2 5 3.5 Cc1ccc(N2C(=O)NC(=O)/C(=C/Nc3ncc(Br)cc3Br)C2=O)cc1 nan
CHEMBL1526117 45215 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 3 2 5 3.5 Cc1ccc(N2C(=O)NC(=O)/C(=C/Nc3ncc(Br)cc3Br)C2=O)cc1 nan
579848 45273 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 1 3 4.7 O=C(Nc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)c1ccccc1F nan
CHEMBL1526496 45273 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 1 3 4.7 O=C(Nc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)c1ccccc1F nan
16018883 45334 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 4 4.6 Cc1ccc(C)c(NC(=O)CCCN2C(=O)C(c3ccccc3)Oc3cccnc32)c1 nan
CHEMBL1527105 45334 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 4 4.6 Cc1ccc(C)c(NC(=O)CCCN2C(=O)C(c3ccccc3)Oc3cccnc32)c1 nan
2765322 45380 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 1 7 1.1 N#Cc1cc(C#N)c(N2CCN(c3ccccn3)CC2)nc1N nan
CHEMBL1527484 45380 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 1 7 1.1 N#Cc1cc(C#N)c(N2CCN(c3ccccn3)CC2)nc1N nan
16009430 45413 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 3.7 CCC(CC)C(=O)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1527797 45413 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 3.7 CCC(CC)C(=O)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
16015678 45414 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 5 5.1 CCC(=O)Nc1ccc2nc(SCCOc3ccc(C)cc3)sc2c1 nan
CHEMBL1527810 45414 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 5 5.1 CCC(=O)Nc1ccc2nc(SCCOc3ccc(C)cc3)sc2c1 nan
16009490 45462 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1cccc(C(=O)Nc2cccc(OCc3cc(=O)n4c(C)csc4n3)c2)c1 nan
CHEMBL1528261 45462 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1cccc(C(=O)Nc2cccc(OCc3cc(=O)n4c(C)csc4n3)c2)c1 nan
16016701 45465 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 2.6 COC(=O)c1ccccc1NC(=O)CCC(=O)N1CCOc2ccccc21 nan
CHEMBL1528274 45465 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 2.6 COC(=O)c1ccccc1NC(=O)CCC(=O)N1CCOc2ccccc21 nan
16391033 45481 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 3 3.8 COc1cc2ccccc2cc1C(=O)Nc1ccc(C)cn1 nan
CHEMBL1528436 45481 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 3 3.8 COc1cc2ccccc2cc1C(=O)Nc1ccc(C)cn1 nan
7185472 45503 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 2 6 2.6 CCOC(=O)c1ccccc1NC(=O)CSc1nc(=O)[nH]c2c1CCCC2 nan
CHEMBL1528587 45503 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 2 6 2.6 CCOC(=O)c1ccccc1NC(=O)CSc1nc(=O)[nH]c2c1CCCC2 nan
5310045 45557 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 5 4.2 Cc1c(C(=O)Nc2ccncc2)sc2nc(-c3ccc(F)cc3)cn12 nan
CHEMBL1529086 45557 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 5 4.2 Cc1c(C(=O)Nc2ccncc2)sc2nc(-c3ccc(F)cc3)cn12 nan
5146627 45595 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 0 6 5.1 COCCN(CCOC)c1ncnc2c1c(-c1ccccc1)cn2-c1ccc(C)c(Cl)c1 nan
CHEMBL1529403 45595 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 0 6 5.1 COCCN(CCOC)c1ncnc2c1c(-c1ccccc1)cn2-c1ccc(C)c(Cl)c1 nan
5181996 45609 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 4 0 6 1.0 CCOC(=O)Cc1nc2ccccc2n(CC#N)c1=O nan
CHEMBL1529516 45609 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 4 0 6 1.0 CCOC(=O)Cc1nc2ccccc2n(CC#N)c1=O nan
2099952 45636 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 4 4.9 Oc1nc(Cc2ccc(F)cc2)nc2scc(-c3ccc(F)cc3)c12 nan
CHEMBL1529751 45636 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 4 4.9 Oc1nc(Cc2ccc(F)cc2)nc2scc(-c3ccc(F)cc3)c12 nan
4373285 45664 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1Br nan
CHEMBL1529998 45664 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1Br nan
16024591 45709 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 5 3.4 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCCc3ccccc3)c2n1 nan
CHEMBL1530480 45709 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 5 3.4 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCCc3ccccc3)c2n1 nan
4994836 45860 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 3 5.0 Cc1ccccc1Nc1cc(C(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1531717 45860 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 3 5.0 Cc1ccccc1Nc1cc(C(=O)NC2CCCC2)c2ccccc2n1 nan
982830 45905 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 4.7 Cc1cc2nnc(SCC(=O)Nc3ccc(F)c(Cl)c3)n2c2ccccc12 nan
CHEMBL1532117 45905 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 4.7 Cc1cc2nnc(SCC(=O)Nc3ccc(F)c(Cl)c3)n2c2ccccc12 nan
895668 45921 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 4 3.2 CC(=O)c1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 nan
CHEMBL1532290 45921 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 4 3.2 CC(=O)c1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 nan
2078424 45987 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 2 4 2.9 COc1cccc(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)c1 nan
CHEMBL1532835 45987 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 2 4 2.9 COc1cccc(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)c1 nan
718477 45990 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 1 0 6 2.1 COc1nc(C)nc2c1sc(=S)n2C nan
CHEMBL1532843 45990 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 1 0 6 2.1 COc1nc(C)nc2c1sc(=S)n2C nan
3239288 46030 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 6 2.9 CCC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(=O)O nan
CHEMBL1533246 46030 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 6 2.9 CCC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(=O)O nan
16025355 46069 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 7 1 6 5.5 CCc1ccccc1NC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(C)cc1)S2(=O)=O nan
CHEMBL1533601 46069 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 7 1 6 5.5 CCc1ccccc1NC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(C)cc1)S2(=O)=O nan
3214708 46089 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 2 8 2.5 CC(=O)Nc1ccc(S(=O)(=O)N2CCN(Cc3nc(O)c4c(C)c(C)sc4n3)CC2)cc1 nan
CHEMBL1533736 46089 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 2 8 2.5 CC(=O)Nc1ccc(S(=O)(=O)N2CCN(Cc3nc(O)c4c(C)c(C)sc4n3)CC2)cc1 nan
16028279 46105 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 1 8 3.2 CCOc1ccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)cc1 nan
CHEMBL1533861 46105 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 1 8 3.2 CCOc1ccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)cc1 nan
4046943 46122 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 6 2.5 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCC3)no1 nan
CHEMBL1534012 46122 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 6 2.5 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCC3)no1 nan
3932775 46138 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 3.8 CCc1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1 nan
CHEMBL1534252 46138 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 3.8 CCc1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1 nan
4658600 46174 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 7 1 6 6.0 CCN(CC)C(=O)c1sc(NC(=O)C2c3ccccc3Oc3ccccc32)c(C(=O)OC(C)C)c1C nan
CHEMBL1534562 46174 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 7 1 6 6.0 CCN(CC)C(=O)c1sc(NC(=O)C2c3ccccc3Oc3ccccc32)c(C(=O)OC(C)C)c1C nan
16025630 46220 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 5 1 7 3.7 COc1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
CHEMBL1535077 46220 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 5 1 7 3.7 COc1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
3185711 46233 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 9 3 8 2.6 CN(C)c1ccc(C(C(=O)NCC2CCCO2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2)cc1 nan
CHEMBL1535224 46233 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 9 3 8 2.6 CN(C)c1ccc(C(C(=O)NCC2CCCO2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2)cc1 nan
54677757 46270 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 1 4 3.4 Cn1c(=O)c(Sc2ccccc2)c(O)c2ccccc21 nan
CHEMBL1535623 46270 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 1 4 3.4 Cn1c(=O)c(Sc2ccccc2)c(O)c2ccccc21 nan
4792884 46303 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 1 6 2.9 COc1ccc(Br)cc1-c1nc2c(c(=O)[nH]c(=O)n2Cc2ccccc2)n1C nan
CHEMBL1535940 46303 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 1 6 2.9 COc1ccc(Br)cc1-c1nc2c(c(=O)[nH]c(=O)n2Cc2ccccc2)n1C nan
135516269 46335 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 8 2 8 3.1 CCOc1ccc(-n2c(SCC(=O)NC(C)CC)nc3nnc(C)c-3c2N)cc1 nan
CHEMBL1536353 46335 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 8 2 8 3.1 CCOc1ccc(-n2c(SCC(=O)NC(C)CC)nc3nnc(C)c-3c2N)cc1 nan
3208311 46355 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 3 9 2.5 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1cnc(O)nc1O)OCO3 nan
CHEMBL1536575 46355 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 3 9 2.5 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1cnc(O)nc1O)OCO3 nan
1965061 46410 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 0 6 4.0 CCCCCc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1Cc1ccc(OC)cc1 nan
CHEMBL1536987 46410 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 0 6 4.0 CCCCCc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1Cc1ccc(OC)cc1 nan
2296181 46453 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 3 2.4 O=C(CNC(=S)NC(=O)C1CCCCC1)c1ccccc1 nan
CHEMBL1537419 46453 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 3 2.4 O=C(CNC(=S)NC(=O)C1CCCCC1)c1ccccc1 nan
4358102 46485 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 3.8 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(c2ccc(F)cc2)CC1 nan
CHEMBL1537648 46485 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 3.8 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(c2ccc(F)cc2)CC1 nan
16194098 46504 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 6 3.6 CSc1ccc(CNc2nc3ccccc3n3cnnc23)cc1 nan
CHEMBL1537791 46504 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 6 3.6 CSc1ccc(CNc2nc3ccccc3n3cnnc23)cc1 nan
1272394 46605 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 6 1 7 3.5 COc1ccc(C(=O)Nc2nnc(Cc3cccs3)s2)cc1OC nan
CHEMBL1538560 46605 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 6 1 7 3.5 COc1ccc(C(=O)Nc2nnc(Cc3cccs3)s2)cc1OC nan
921484 46701 13 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 4 4.1 O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1 nan
CHEMBL1539494 46701 13 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 4 4.1 O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1 nan
664170 46772 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 0 8 3.5 CCOC(=O)N1CCN(c2nc(SC)nc3sc4c(c23)CC(C)(C)OC4)CC1 nan
CHEMBL1540011 46772 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 0 8 3.5 CCOC(=O)N1CCN(c2nc(SC)nc3sc4c(c23)CC(C)(C)OC4)CC1 nan
6621296 46855 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 6 3.3 O=C(NCc1ccccc1)C1CCCN(c2nc3ccsc3c(=O)s2)C1 nan
CHEMBL1540762 46855 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 6 3.3 O=C(NCc1ccccc1)C1CCCN(c2nc3ccsc3c(=O)s2)C1 nan
2855521 46921 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 2 4 3.2 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccc(F)cc2)cc1 nan
CHEMBL1541261 46921 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 2 4 3.2 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccc(F)cc2)cc1 nan
687554 46949 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 1 4 3.1 CC(=O)Oc1ccc2oc(-c3ccccc3)c(C(N)=O)c2c1 nan
CHEMBL1541470 46949 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 1 4 3.1 CC(=O)Oc1ccc2oc(-c3ccccc3)c(C(N)=O)c2c1 nan
16746196 47129 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 10 3 5 3.2 CCCCNc1ccc(C(CC(N)=O)NC(=O)c2ccccc2)cc1[N+](=O)[O-] nan
CHEMBL1543039 47129 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 10 3 5 3.2 CCCCNc1ccc(C(CC(N)=O)NC(=O)c2ccccc2)cc1[N+](=O)[O-] nan
654907 47143 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 6 4.5 COc1ccc(C(=O)Nc2cccc(-c3nc4ncccc4o3)c2C)cc1OC nan
CHEMBL1543164 47143 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 6 4.5 COc1ccc(C(=O)Nc2cccc(-c3nc4ncccc4o3)c2C)cc1OC nan
899145 47171 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 2 0 5 4.1 Cc1cnn(C(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)c1 nan
CHEMBL1543380 47171 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 2 0 5 4.1 Cc1cnn(C(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)c1 nan
1337412 47175 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.2 CCOc1ccc(-c2nn(-c3ccccc3)cc2/C=C2\SC(N)=NC2=O)cc1C nan
146674638 47175 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.2 CCOc1ccc(-c2nn(-c3ccccc3)cc2/C=C2\SC(N)=NC2=O)cc1C nan
CHEMBL1543421 47175 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.2 CCOc1ccc(-c2nn(-c3ccccc3)cc2/C=C2\SC(N)=NC2=O)cc1C nan
1773311 47220 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 7 3.1 CCN(CC)C(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
CHEMBL1543838 47220 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 7 3.1 CCN(CC)C(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
22553577 47291 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 5 3.5 O=C(CCCn1c(=O)c2cccn2c2cccnc21)NCc1cccc(Br)c1 nan
CHEMBL1544274 47291 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 5 3.5 O=C(CCCn1c(=O)c2cccn2c2cccnc21)NCc1cccc(Br)c1 nan
2150501 47471 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 1 8 3.5 COCCn1c(SCC(=O)Nc2ccc(OC)cc2)nc2c(oc3ccccc32)c1=O nan
CHEMBL1545636 47471 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 1 8 3.5 COCCn1c(SCC(=O)Nc2ccc(OC)cc2)nc2c(oc3ccccc32)c1=O nan
1131000 47479 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 2 5 3.2 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2F)c1C nan
CHEMBL1545709 47479 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 2 5 3.2 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2F)c1C nan
4975679 47575 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 1 1 1 4.0 O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCc2ccccc2C1 nan
CHEMBL1546589 47575 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 1 1 1 4.0 O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCc2ccccc2C1 nan
4099286 47622 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 8 1 4 3.8 CCOc1ccc(CNC(=O)CCc2cn(C)c3ccccc23)cc1OC nan
CHEMBL1547036 47622 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 8 1 4 3.8 CCOc1ccc(CNC(=O)CCc2cn(C)c3ccccc23)cc1OC nan
246421 47631 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 3 6 3.0 CSc1nc(O)c(Nc2cccc(Cl)c2)c(O)n1 nan
CHEMBL1547116 47631 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 3 6 3.0 CSc1nc(O)c(Nc2cccc(Cl)c2)c(O)n1 nan
3179963 47741 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 8 3 7 2.3 CCC(C(=O)NC1CCCC1)N(C(=O)c1snc(C(N)=O)c1N)c1ccc(OC)cc1 nan
CHEMBL1548213 47741 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 8 3 7 2.3 CCC(C(=O)NC1CCCC1)N(C(=O)c1snc(C(N)=O)c1N)c1ccc(OC)cc1 nan
16608827 47760 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 5 3.8 COc1ccc(S(=O)(=O)N2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1NC(C)=O nan
CHEMBL1548379 47760 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 5 3.8 COc1ccc(S(=O)(=O)N2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1NC(C)=O nan
1711150 47868 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 8 1 6 3.6 COc1cc(/C=C/C(=O)OCC(=O)Nc2ccccc2Cl)cc(OC)c1OC nan
CHEMBL1549297 47868 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 8 1 6 3.6 COc1cc(/C=C/C(=O)OCC(=O)Nc2ccccc2Cl)cc(OC)c1OC nan
4371420 47873 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 0 4 2.9 O=C(COC(=O)c1ccc(N2CCCC2=O)cc1)c1ccccc1 nan
CHEMBL1549350 47873 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 0 4 2.9 O=C(COC(=O)c1ccc(N2CCCC2=O)cc1)c1ccccc1 nan
650104 48001 2 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 3.8 CCc1cc2ccc(OC)cc2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1550363 48001 2 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 3.8 CCc1cc2ccc(OC)cc2nc1SCC(=O)Nc1cc(C)on1 nan
891743 48046 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 4.5 Cc1nc(-c2ccc(C(=O)Nc3ccc(F)cc3)cc2)cs1 nan
CHEMBL1550704 48046 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 4.5 Cc1nc(-c2ccc(C(=O)Nc3ccc(F)cc3)cc2)cs1 nan
135437051 48091 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 3 6 4.1 CCc1ccccc1NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1cccc(C)c1 nan
CHEMBL1551159 48091 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 3 6 4.1 CCc1ccccc1NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1cccc(C)c1 nan
16030615 48095 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 6 0 9 3.1 COc1ccc(C(=O)N2CCN(Cc3cc(=O)n4nc(-c5ccccc5C)sc4n3)CC2)cc1OC nan
CHEMBL1551229 48095 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 6 0 9 3.1 COc1ccc(C(=O)N2CCN(Cc3cc(=O)n4nc(-c5ccccc5C)sc4n3)CC2)cc1OC nan
16018080 48098 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 1 6 3.5 COc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1OC nan
CHEMBL1551250 48098 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 1 6 3.5 COc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1OC nan
16012980 48107 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 3 5.3 Cc1ccc2nc(O)c(CN(C(=O)c3cccc(Cl)c3)C(C)(C)C)cc2c1 nan
CHEMBL1551350 48107 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 3 5.3 Cc1ccc2nc(O)c(CN(C(=O)c3cccc(Cl)c3)C(C)(C)C)cc2c1 nan
3534311 48114 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 2 6 2.0 NS(=O)(=O)c1ccc2nc(NC(=O)COc3ccccc3)sc2c1 nan
CHEMBL1551511 48114 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 2 6 2.0 NS(=O)(=O)c1ccc2nc(NC(=O)COc3ccccc3)sc2c1 nan
16030318 48116 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.5 CCOc1ccc(C(=O)Nc2nnc(SCc3cc(=O)n4ccccc4n3)s2)cc1 nan
CHEMBL1551529 48116 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.5 CCOc1ccc(C(=O)Nc2nnc(SCc3cc(=O)n4ccccc4n3)s2)cc1 nan
16031341 48122 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 2 1 5 1.9 Cc1ccccc1C(=O)Nc1nnc2n1CCS2 nan
CHEMBL1551637 48122 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 2 1 5 1.9 Cc1ccccc1C(=O)Nc1nnc2n1CCS2 nan
16012572 48126 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.4 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)NCc3ccc(Cl)cc3)c(C)nc21 nan
CHEMBL1551773 48126 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.4 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)NCc3ccc(Cl)cc3)c(C)nc21 nan
4112916 48140 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 0 5 5.2 CCOc1nc(-c2ccccc2)ccc1-c1noc(-c2ccc(C)cc2)n1 nan
CHEMBL1551932 48140 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 0 5 5.2 CCOc1nc(-c2ccccc2)ccc1-c1noc(-c2ccc(C)cc2)n1 nan
16030647 48142 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 6 0 8 3.6 CC(Oc1ccccc1)C(=O)N1CCN(Cc2cc(=O)n3nc(-c4ccccc4Cl)sc3n2)CC1 nan
CHEMBL1551961 48142 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 6 0 8 3.6 CC(Oc1ccccc1)C(=O)N1CCN(Cc2cc(=O)n3nc(-c4ccccc4Cl)sc3n2)CC1 nan
4069977 48150 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 4 6.3 CCOc1ccc(Sc2cc(C(=O)NC(C)c3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1552026 48150 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 4 6.3 CCOc1ccc(Sc2cc(C(=O)NC(C)c3ccccc3)c3ccccc3n2)cc1 nan
16027075 48158 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 0 8 4.8 COc1ccc(-c2nc(Cn3c(=O)cc(C)c4c(C)nn(-c5ccccc5)c43)c(C)o2)cc1OC nan
CHEMBL1552119 48158 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 0 8 4.8 COc1ccc(-c2nc(Cn3c(=O)cc(C)c4c(C)nn(-c5ccccc5)c43)c(C)o2)cc1OC nan
24792649 48162 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 0 0 3 3.5 Cn1c2ccccc2c(=O)c2ccc(C#Cc3ccccn3)cc21 nan
CHEMBL1552163 48162 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 0 0 3 3.5 Cn1c2ccccc2c(=O)c2ccc(C#Cc3ccccn3)cc21 nan
16020555 48184 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 0 5 4.8 O=c1c(S(=O)(=O)c2ccccc2)cn(Cc2cccc(F)c2)c2cc(N3CCCC3)c(F)cc12 nan
CHEMBL1552450 48184 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 0 5 4.8 O=c1c(S(=O)(=O)c2ccccc2)cn(Cc2cccc(F)c2)c2cc(N3CCCC3)c(F)cc12 nan
7217107 48187 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 2.4 Cc1ccc(NC(=O)c2cnc(SCC(=O)Nc3cc(C)on3)n(C)c2=O)cc1 nan
CHEMBL1552487 48187 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 2.4 Cc1ccc(NC(=O)c2cnc(SCC(=O)Nc3cc(C)on3)n(C)c2=O)cc1 nan
3666941 48188 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 6 1 6 4.9 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2-c2ccc(Br)cc2)cc1 nan
CHEMBL1552556 48188 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 6 1 6 4.9 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2-c2ccc(Br)cc2)cc1 nan
16010970 48201 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 0 7 3.6 CCc1cc2c(cc3c(=O)n(CC(=O)N4CCN(c5cc(Cl)ccc5C)CC4)ncn32)s1 nan
CHEMBL1552740 48201 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 0 7 3.6 CCc1cc2c(cc3c(=O)n(CC(=O)N4CCN(c5cc(Cl)ccc5C)CC4)ncn32)s1 nan
16021520 48204 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 4 4.6 CSc1ncc(C(=O)NCc2cccc(Br)c2)c(-c2ccccc2)n1 nan
CHEMBL1552765 48204 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 4 4.6 CSc1ncc(C(=O)NCc2cccc(Br)c2)c(-c2ccccc2)n1 nan
16024485 48223 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 5 3.9 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3C)c2n1 nan
CHEMBL1553018 48223 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 5 3.9 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3C)c2n1 nan
3160964 48227 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.6 Cc1cccc(OCC(=O)Nc2c(C)ccc3nsnc23)c1C nan
CHEMBL1553050 48227 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.6 Cc1cccc(OCC(=O)Nc2c(C)ccc3nsnc23)c1C nan
16012361 48275 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 5 4.2 CCc1ccccc1NC(=O)Cn1ncc2c(C)n(Cc3ccccc3F)c(C)c2c1=O nan
CHEMBL1553757 48275 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 5 4.2 CCc1ccccc1NC(=O)Cn1ncc2c(C)n(Cc3ccccc3F)c(C)c2c1=O nan
16027446 48291 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 8 3.8 O=C(OCc1cc(=O)n2nc(C3CC3)sc2n1)c1ccc(NC(=O)c2ccccc2F)cc1 nan
CHEMBL1553997 48291 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 8 3.8 O=C(OCc1cc(=O)n2nc(C3CC3)sc2n1)c1ccc(NC(=O)c2ccccc2F)cc1 nan
16030862 48318 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 3 3.1 CC(=O)N1CCc2cc(CNS(=O)(=O)c3ccccc3C(F)(F)F)ccc21 nan
CHEMBL1554375 48318 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 3 3.1 CC(=O)N1CCc2cc(CNS(=O)(=O)c3ccccc3C(F)(F)F)ccc21 nan
16030106 48327 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1ccc(CNC(=O)Cn2nc(C)c3nn(-c4ccc(Cl)cc4)c(C)c3c2=O)cc1 nan
CHEMBL1554505 48327 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1ccc(CNC(=O)Cn2nc(C)c3nn(-c4ccc(Cl)cc4)c(C)c3c2=O)cc1 nan
4074992 48333 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 4 5.9 CCOc1ccc(Sc2cc(C(=O)NCc3ccc(F)cc3)c3ccccc3n2)cc1 nan
CHEMBL1554644 48333 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 4 5.9 CCOc1ccc(Sc2cc(C(=O)NCc3ccc(F)cc3)c3ccccc3n2)cc1 nan
5058559 48345 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 2.9 CC(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)N3CC(C)OC(C)C3)cc2)c1 nan
CHEMBL1554762 48345 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 2.9 CC(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)N3CC(C)OC(C)C3)cc2)c1 nan
16026882 48346 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 8 3.5 O=C(COc1ccc(F)cc1)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
CHEMBL1554822 48346 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 8 3.5 O=C(COc1ccc(F)cc1)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
4289361 48360 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.3 CCOc1cccc(C(=O)Nc2c(C(=O)c3ccc(OC)cc3)oc3ccccc23)c1 nan
CHEMBL1555049 48360 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.3 CCOc1cccc(C(=O)Nc2c(C(=O)c3ccc(OC)cc3)oc3ccccc23)c1 nan
3282564 48367 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 1 4 4.6 Cc1ccc(-c2nnc(NC(=O)c3c(F)cccc3Cl)s2)cc1 nan
CHEMBL1555127 48367 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 1 4 4.6 Cc1ccc(-c2nnc(NC(=O)c3c(F)cccc3Cl)s2)cc1 nan
16009325 48378 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 7 3.2 O=C(Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2cc3c(cc21)OCO3)Nc1ccccc1 nan
CHEMBL1555288 48378 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 7 3.2 O=C(Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2cc3c(cc21)OCO3)Nc1ccccc1 nan
135416425 48381 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 2 4 5.1 Cc1ccccc1C(=O)Nc1cc(C)c(O)c(-c2nc3ccccc3o2)c1 nan
CHEMBL1555312 48381 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 2 4 5.1 Cc1ccccc1C(=O)Nc1cc(C)c(O)c(-c2nc3ccccc3o2)c1 nan
16023840 48431 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 6 4.3 CCOC(=O)c1c(C)oc2nc(C)nc(NCc3ccccc3Cl)c12 nan
CHEMBL1555863 48431 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 6 4.3 CCOC(=O)c1c(C)oc2nc(C)nc(NCc3ccccc3Cl)c12 nan
4432211 48440 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 2 1 6 2.5 CC(=O)N1CCc2c(sc(NC(=O)c3ccc4c(c3)OCCO4)c2C#N)C1 nan
CHEMBL1555967 48440 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 2 1 6 2.5 CC(=O)N1CCc2c(sc(NC(=O)c3ccc4c(c3)OCCO4)c2C#N)C1 nan
929959 48475 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 8 0.8 COc1ccc(-c2c(C#N)c(N)nc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1556274 48475 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 8 0.8 COc1ccc(-c2c(C#N)c(N)nc3c2c(=O)n(C)c(=O)n3C)cc1 nan
1718133 48503 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 2 5 4.3 CCCCCC(=O)NC(=S)Nc1cccc(-c2nc3ncccc3o2)c1 nan
CHEMBL1556586 48503 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 2 5 4.3 CCCCCC(=O)NC(=S)Nc1cccc(-c2nc3ncccc3o2)c1 nan
1475314 48514 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 251 2 1 4 3.2 Cc1nc(N)ncc1Sc1ccc(Cl)cc1 nan
CHEMBL1556672 48514 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 251 2 1 4 3.2 Cc1nc(N)ncc1Sc1ccc(Cl)cc1 nan
1829088 48566 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 5 2.5 COCCNC(=O)Cn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O nan
CHEMBL1557090 48566 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 5 2.5 COCCNC(=O)Cn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O nan
16008924 48576 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 3 1 4 3.6 Cn1c(C(=O)NCc2ccc(Cl)cc2)cc2c(=O)n(C)c3ccccc3c21 nan
CHEMBL1557189 48576 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 3 1 4 3.6 Cn1c(C(=O)NCc2ccc(Cl)cc2)cc2c(=O)n(C)c3ccccc3c21 nan
20868637 48619 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 5 3.8 CCOc1ccc2ncc(S(=O)(=O)c3ccc(C)c(C)c3)c(O)c2c1 nan
CHEMBL1557551 48619 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 5 3.8 CCOc1ccc2ncc(S(=O)(=O)c3ccc(C)c(C)c3)c(O)c2c1 nan
16030924 48635 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 6 5.1 COc1ccc(-c2cn3nc(SCC(=O)Nc4ccc(C)c(Cl)c4)ccc3n2)cc1 nan
CHEMBL1557656 48635 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 6 5.1 COc1ccc(-c2cn3nc(SCC(=O)Nc4ccc(C)c(Cl)c4)ccc3n2)cc1 nan
899391 48640 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 4 2.8 O=C(Cc1ccccc1)Nc1nc(=O)c2ccccc2s1 nan
CHEMBL1557721 48640 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 4 2.8 O=C(Cc1ccccc1)Nc1nc(=O)c2ccccc2s1 nan
3846782 48642 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 4 1 7 4.1 Cc1ccc(Cn2c(=N)c(S(=O)(=O)c3ccc(Br)cc3)cc3c(=O)n4ccccc4nc32)cc1 nan
CHEMBL1557740 48642 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 4 1 7 4.1 Cc1ccc(Cn2c(=N)c(S(=O)(=O)c3ccc(Br)cc3)cc3c(=O)n4ccccc4nc32)cc1 nan
1485561 48664 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 3 0 5 4.4 O=S(=O)(c1ccccc1)c1cnn2c(C(F)(F)F)cc(-c3ccc(F)cc3)nc12 nan
CHEMBL1557929 48664 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 3 0 5 4.4 O=S(=O)(c1ccccc1)c1cnn2c(C(F)(F)F)cc(-c3ccc(F)cc3)nc12 nan
54706216 48720 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 3 4 3.5 O=C(NC1CCCCCCC1)c1c(O)nc2ccccc2c1O nan
CHEMBL1558469 48720 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 3 4 3.5 O=C(NC1CCCCCCC1)c1c(O)nc2ccccc2c1O nan
5185520 48731 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 4 2 4 2.5 Nc1cc(Cl)ccc1C(=O)OCC(=O)NC1CCCCC1 nan
CHEMBL1558534 48731 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 4 2 4 2.5 Nc1cc(Cl)ccc1C(=O)OCC(=O)NC1CCCCC1 nan
666603 48765 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 6 4.1 Cc1nn(-c2ccc(F)cc2)c2nc(N)c(C#N)c(-c3cccs3)c12 nan
CHEMBL1558784 48765 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 6 4.1 Cc1nn(-c2ccc(F)cc2)c2nc(N)c(C#N)c(-c3cccs3)c12 nan
15991438 48773 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 6 3.8 Cc1cccc(NC(=O)CSc2nc3ccccc3nc2N2CCOCC2)c1C nan
CHEMBL1558859 48773 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 6 3.8 Cc1cccc(NC(=O)CSc2nc3ccccc3nc2N2CCOCC2)c1C nan
950988 48789 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 2 5 4.8 COc1cccc(Nc2nc(-c3ccccc3O)nc3ccccc23)c1 nan
CHEMBL1558977 48789 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 2 5 4.8 COc1cccc(Nc2nc(-c3ccccc3O)nc3ccccc23)c1 nan
4345257 48800 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 6 2 6 3.2 Cc1cc(C)cc(NC(=O)CSc2nnc(NC(=O)C3CC3)s2)c1 nan
CHEMBL1559060 48800 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 6 2 6 3.2 Cc1cc(C)cc(NC(=O)CSc2nnc(NC(=O)C3CC3)s2)c1 nan
900716 48812 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 3 1 5 3.6 COC(=O)c1ccc(NC(=O)c2ccc3nc(C)sc3c2)cc1 nan
CHEMBL1559158 48812 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 3 1 5 3.6 COC(=O)c1ccc(NC(=O)c2ccc3nc(C)sc3c2)cc1 nan
2156049 48882 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 4 5.5 Cc1ccc(-n2c(SCc3ccccc3)nc3c([nH]c4ccccc43)c2=O)cc1 nan
CHEMBL1559857 48882 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 4 5.5 Cc1ccc(-n2c(SCc3ccccc3)nc3c([nH]c4ccccc43)c2=O)cc1 nan
3138574 48885 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 3 4 3.6 O=C(NNc1c2ccccc2nc2ccccc12)C(O)c1ccccc1 nan
CHEMBL1559872 48885 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 3 4 3.6 O=C(NNc1c2ccccc2nc2ccccc12)C(O)c1ccccc1 nan
16017814 48904 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 6 2.9 COc1ccc(Cl)cc1NC(=O)Cn1ccn(-c2cc(C)cc(C)c2)c(=O)c1=O nan
CHEMBL1560031 48904 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 6 2.9 COc1ccc(Cl)cc1NC(=O)Cn1ccn(-c2cc(C)cc(C)c2)c(=O)c1=O nan
2028031 48978 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 1 0 5 3.5 Cc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1C1CCCCCC1 nan
CHEMBL1560823 48978 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 1 0 5 3.5 Cc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1C1CCCCCC1 nan
4690835 48981 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 COc1ccc2oc(-c3cccc(NC(=O)c4ccc(C#N)cc4F)c3)nc2c1 nan
CHEMBL1560860 48981 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 COc1ccc2oc(-c3cccc(NC(=O)c4ccc(C#N)cc4F)c3)nc2c1 nan
15990056 49153 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 5 4.4 CCc1nnc2c3ccccc3nc(Nc3ccc(F)c(Cl)c3)n12 nan
CHEMBL1562390 49153 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 5 4.4 CCc1nnc2c3ccccc3nc(Nc3ccc(F)c(Cl)c3)n12 nan
5299641 49157 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 4 4.6 Cc1ccc(Cl)cc1NC(=O)CSc1nc(C)c(C)c(C)c1C#N nan
CHEMBL1562426 49157 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 4 4.6 Cc1ccc(Cl)cc1NC(=O)CSc1nc(C)c(C)c(C)c1C#N nan
135496880 49160 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 2 9 3.5 Oc1nc(SCc2nc(O)c3cnn(-c4ccccc4)c3n2)nc2ccccc12 nan
CHEMBL1562459 49160 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 2 9 3.5 Oc1nc(SCc2nc(O)c3cnn(-c4ccccc4)c3n2)nc2ccccc12 nan
1176245 49206 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 4.0 CCOc1ccc2nc(SCC(=O)Nc3cc(C)on3)c(C)cc2c1 nan
CHEMBL1562840 49206 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 4.0 CCOc1ccc2nc(SCC(=O)Nc3cc(C)on3)c(C)cc2c1 nan
16030293 49209 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 5 6.0 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)Nc1ccccc1C(F)(F)F nan
CHEMBL1562857 49209 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 5 6.0 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)Nc1ccccc1C(F)(F)F nan
16008836 49288 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.2 O=C(NCCCN1CCN(c2ccc(F)cc2)CC1)c1cc2c(Cl)nc3ccccc3c2s1 nan
CHEMBL1563658 49288 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.2 O=C(NCCCN1CCN(c2ccc(F)cc2)CC1)c1cc2c(Cl)nc3ccccc3c2s1 nan
258436 49358 46 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 1 0 2 2.5 CN1C=CC(=CC=C2C=CC(=O)C=C2)C=C1 nan
CHEMBL1564141 49358 46 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 1 0 2 2.5 CN1C=CC(=CC=C2C=CC(=O)C=C2)C=C1 nan
16030542 49377 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1ccc(OCC(=O)Nc2cccc(OCc3cc(=O)n4ccccc4n3)c2)cc1C nan
CHEMBL1564400 49377 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1ccc(OCC(=O)Nc2cccc(OCc3cc(=O)n4ccccc4n3)c2)cc1C nan
2819137 49437 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 1 6 2.3 COc1cccc(-c2nc(N)nc(SC)c2C#N)c1 nan
CHEMBL1564918 49437 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 1 6 2.3 COc1cccc(-c2nc(N)nc(SC)c2C#N)c1 nan
3244591 49441 1 None -100 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 0 6 4.3 CC(C)CCn1c(SCC#N)nc2c(sc3ccccc32)c1=O nan
CHEMBL1564940 49441 1 None -100 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 0 6 4.3 CC(C)CCn1c(SCC#N)nc2c(sc3ccccc32)c1=O nan
16010206 49453 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 7 1.6 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1 nan
CHEMBL1565063 49453 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 7 1.6 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1 nan
1147655 49456 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 7 3.0 COc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1OC nan
CHEMBL1565079 49456 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 7 3.0 COc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1OC nan
694360 49505 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 5 3.1 N#Cc1c(-c2cccs2)cc(C2CC2)nc1SCC(N)=O nan
CHEMBL1565417 49505 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 5 3.1 N#Cc1c(-c2cccs2)cc(C2CC2)nc1SCC(N)=O nan
16021091 49549 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 6 5.8 COc1ccc(Cn2c(SCc3ccc(C(=O)NC4CCCCC4)cc3)nc3cccnc32)cc1 nan
CHEMBL1565772 49549 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 6 5.8 COc1ccc(Cn2c(SCc3ccc(C(=O)NC4CCCCC4)cc3)nc3cccnc32)cc1 nan
16019049 49635 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 7 3.6 COc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)c(OC)c1 nan
CHEMBL1566421 49635 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 7 3.6 COc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)c(OC)c1 nan
2810064 49643 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 7 2.5 COc1cc2nc(NC(=O)c3ccco3)sc(=O)c2cc1OC nan
CHEMBL1566488 49643 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 7 2.5 COc1cc2nc(NC(=O)c3ccco3)sc(=O)c2cc1OC nan
15988926 49797 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 12 1 7 3.0 CCN(CC)C(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2)c(=O)c2sccc21 nan
CHEMBL1567696 49797 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 12 1 7 3.0 CCN(CC)C(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2)c(=O)c2sccc21 nan
16017081 49887 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 6 4.5 CCC(C(=O)Nc1ccccc1OC)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1568421 49887 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 6 4.5 CCC(C(=O)Nc1ccccc1OC)n1nc(C)c2sc3ccccc3c2c1=O nan
16030322 49938 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 8 2.9 CCCC(=O)Nc1nnc(SCc2cc(=O)n3cccc(C)c3n2)s1 nan
CHEMBL1568901 49938 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 8 2.9 CCCC(=O)Nc1nnc(SCc2cc(=O)n3cccc(C)c3n2)s1 nan
713644 49954 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 5 1.4 Cc1cn(C(=O)CN2C(=O)c3ccccc3C2=O)c(C)n1 nan
CHEMBL1569010 49954 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 5 1.4 Cc1cn(C(=O)CN2C(=O)c3ccccc3C2=O)c(C)n1 nan
16024577 49993 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 3.7 COc1cc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc(OC)c1 nan
CHEMBL1569365 49993 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 3.7 COc1cc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc(OC)c1 nan
1146106 50017 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 1 5 5.2 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCc3ccc(Cl)cc3)n2)cc1 nan
CHEMBL1569521 50017 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 1 5 5.2 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCc3ccc(Cl)cc3)n2)cc1 nan
1433832 50039 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 4 1 4 2.5 N#Cc1cc2ccccc2nc1SCC(=O)NC1CC1 nan
CHEMBL1569775 50039 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 4 1 4 2.5 N#Cc1cc2ccccc2nc1SCC(=O)NC1CC1 nan
660750 50043 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 1 5 2.9 Cn1nnnc1-c1cc(Br)ccc1NC(=O)c1ccccc1 nan
CHEMBL1569814 50043 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 1 5 2.9 Cn1nnnc1-c1cc(Br)ccc1NC(=O)c1ccccc1 nan
16020020 50102 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 5 0 5 4.2 CCOC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccc(C)cc2)c1C nan
CHEMBL1570342 50102 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 5 0 5 4.2 CCOC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccc(C)cc2)c1C nan
893344 50103 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 2 4 3.3 Cn1nnc2cc(NC(=O)Nc3cccc(Cl)c3)ccc21 nan
CHEMBL1570344 50103 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 2 4 3.3 Cn1nnc2cc(NC(=O)Nc3cccc(Cl)c3)ccc21 nan
7692920 50170 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 3.0 O=C(Nc1nnc(S(=O)(=O)Cc2ccc(F)cc2)s1)c1ccccc1F nan
CHEMBL1570825 50170 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 3.0 O=C(Nc1nnc(S(=O)(=O)Cc2ccc(F)cc2)s1)c1ccccc1F nan
16015598 50234 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 6.0 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccccc3)on2)cc1 nan
CHEMBL1571539 50234 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 6.0 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccccc3)on2)cc1 nan
16015076 50298 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 6 4.0 COC(=O)c1ccccc1NC(=O)CSc1cc(-c2ccccc2)nc(C)n1 nan
CHEMBL1572102 50298 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 6 4.0 COC(=O)c1ccccc1NC(=O)CSc1cc(-c2ccccc2)nc(C)n1 nan
663126 50360 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 6 5.1 Clc1ccc(OCc2nn3c(C4CCCCC4)nnc3s2)c(Cl)c1 nan
CHEMBL1572687 50360 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 6 5.1 Clc1ccc(OCc2nn3c(C4CCCCC4)nnc3s2)c(Cl)c1 nan
2318048 50384 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 6 1 7 3.7 COc1ccc(-c2csc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)n2)cc1OC nan
CHEMBL1572874 50384 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 6 1 7 3.7 COc1ccc(-c2csc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)n2)cc1OC nan
135492018 50406 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.4 O=C1N=C(Nc2ccccn2)SC1Cc1ccccc1Cl nan
135635832 50406 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.4 O=C1N=C(Nc2ccccn2)SC1Cc1ccccc1Cl nan
135914561 50406 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.4 O=C1N=C(Nc2ccccn2)SC1Cc1ccccc1Cl nan
CHEMBL1573000 50406 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.4 O=C1N=C(Nc2ccccn2)SC1Cc1ccccc1Cl nan
135870946 50430 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 1 8 1.6 COc1ccc(C(=O)COC(=O)CCNC2=NS(=O)(=O)c3ccccc32)c(OC)c1 nan
CHEMBL1573236 50430 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 1 8 1.6 COc1ccc(C(=O)COC(=O)CCNC2=NS(=O)(=O)c3ccccc32)c(OC)c1 nan
16011872 50434 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 6 0 6 7.1 Cc1cccc(-c2nc(Cn3c(SCc4cccc(C(F)(F)F)c4)nc4ccncc43)c(C)o2)c1 nan
CHEMBL1573276 50434 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 6 0 6 7.1 Cc1cccc(-c2nc(Cn3c(SCc4cccc(C(F)(F)F)c4)nc4ccncc43)c(C)o2)c1 nan
16019020 50447 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.0 Cc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1573442 50447 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.0 Cc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
4599423 50493 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 3 1 5.2 S=C(NCc1ccc2[nH]c3c(c2c1)CCCC3)Nc1ccccc1Cl nan
CHEMBL1573942 50493 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 3 1 5.2 S=C(NCc1ccc2[nH]c3c(c2c1)CCCC3)Nc1ccccc1Cl nan
16014814 50536 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 5.2 Cc1cccc(NC(=O)c2c(C)cc(C)nc2SCC(=O)c2ccccc2)c1 nan
CHEMBL1574276 50536 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 5.2 Cc1cccc(NC(=O)c2c(C)cc(C)nc2SCC(=O)c2ccccc2)c1 nan
921918 50654 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 0 5 4.8 Fc1ccc(-n2c(-c3cccs3)nc3nc4ccccc4nc32)cc1 nan
CHEMBL1575663 50654 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 0 5 4.8 Fc1ccc(-n2c(-c3cccs3)nc3nc4ccccc4nc32)cc1 nan
1960193 50709 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 4 3.9 Cn1c(NC(=O)c2ccccc2)c(-c2ccccn2)c(=O)c2ccccc21 nan
CHEMBL1576207 50709 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 4 3.9 Cn1c(NC(=O)c2ccccc2)c(-c2ccccn2)c(=O)c2ccccc21 nan
5846704 50718 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 9 1 5 3.9 CCN(CC)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1576280 50718 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 9 1 5 3.9 CCN(CC)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
935443 50728 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 3 2 5.1 Cc1ccc(NC(S)=Nc2cc(-c3ccccc3)[nH]n2)cc1Cl nan
CHEMBL1576343 50728 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 3 2 5.1 Cc1ccc(NC(S)=Nc2cc(-c3ccccc3)[nH]n2)cc1Cl nan
3228917 50797 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 2 5 4.7 CCc1cccc(C)c1NC(=O)CSc1[nH]c(-c2ccccc2F)nc2ncnc1-2 nan
CHEMBL1576889 50797 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 2 5 4.7 CCc1cccc(C)c1NC(=O)CSc1[nH]c(-c2ccccc2F)nc2ncnc1-2 nan
709545 50833 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 2.9 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCC3)no1 nan
CHEMBL1577228 50833 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 2.9 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCC3)no1 nan
3917007 50941 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 2.9 O=C1COc2ccc(C(=O)COC(=O)CCSc3ccccc3)cc2N1 nan
CHEMBL1578153 50941 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 2.9 O=C1COc2ccc(C(=O)COC(=O)CCSc3ccccc3)cc2N1 nan
20884721 51128 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 7 1.7 COc1cccc2c1cc1c(=O)n(CC(=O)NCc3ccccn3)nc(C)n12 nan
CHEMBL1579740 51128 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 7 1.7 COc1cccc2c1cc1c(=O)n(CC(=O)NCc3ccccn3)nc(C)n12 nan
1292507 51173 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 1 7 4.4 Cc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3sc(C)c(C)c3c2=O)cc1 nan
CHEMBL1580140 51173 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 1 7 4.4 Cc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3sc(C)c(C)c3c2=O)cc1 nan
2347564 51394 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 9 1.6 Cc1nn(-c2ccccc2)c2sc(C(=O)c3c(N)n(C)c(=O)n(C)c3=O)cc12 nan
CHEMBL1581991 51394 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 9 1.6 Cc1nn(-c2ccccc2)c2sc(C(=O)c3c(N)n(C)c(=O)n(C)c3=O)cc12 nan
1454917 51424 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 4.7 CCc1ccc2c(c1)cc(CN(C(S)=Nc1cccc(C)c1)C1CC1)c1nnnn12 nan
CHEMBL1582197 51424 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 4.7 CCc1ccc2c(c1)cc(CN(C(S)=Nc1cccc(C)c1)C1CC1)c1nnnn12 nan
7080789 51490 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 3 4 3.3 Cc1ccc2cc(CCNC(=O)C(=O)c3c[nH]c4ccccc34)c(O)nc2c1 nan
CHEMBL1582792 51490 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 3 4 3.3 Cc1ccc2cc(CCNC(=O)C(=O)c3c[nH]c4ccccc34)c(O)nc2c1 nan
1420394 51509 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 1 4 5.2 Cc1ccc2cc(CN(C(=O)c3cccs3)c3ccccc3)c(O)nc2c1 nan
CHEMBL1583002 51509 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 1 4 5.2 Cc1ccc2cc(CN(C(=O)c3cccs3)c3ccccc3)c(O)nc2c1 nan
2012958 51556 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 5 4.1 Cc1nc(SCC(=O)NCc2ccccc2)c2oc3ccccc3c2n1 nan
CHEMBL1583344 51556 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 5 4.1 Cc1nc(SCC(=O)NCc2ccccc2)c2oc3ccccc3c2n1 nan
2810452 51582 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 0 6 3.5 Cc1cc(C)c(-n2nnnc2SC2Cc3ccccc3C2=O)c(C)c1 nan
CHEMBL1583573 51582 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 0 6 3.5 Cc1cc(C)c(-n2nnnc2SC2Cc3ccccc3C2=O)c(C)c1 nan
4102688 51669 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 5 2.6 Cc1cccc(NC(=O)c2cnc3sccn3c2=O)c1C nan
CHEMBL1584232 51669 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 5 2.6 Cc1cccc(NC(=O)c2cnc3sccn3c2=O)c1C nan
15944711 51672 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 5 3.9 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccccc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1584268 51672 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 5 3.9 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccccc3)c(=O)c3cc(F)ccc32)cc1 nan
2981373 51922 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 1 4 4.3 Cc1nc(Nc2cccc(C(F)(F)F)c2)nc2c1C(=O)CC(C)C2 nan
CHEMBL1586327 51922 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 1 4 4.3 Cc1nc(Nc2cccc(C(F)(F)F)c2)nc2c1C(=O)CC(C)C2 nan
6404569 52063 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 0 3 5.4 c1ccc(Cc2nnc(Sc3ccccc3)c3ccccc23)cc1 nan
CHEMBL1587518 52063 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 0 3 5.4 c1ccc(Cc2nnc(Sc3ccccc3)c3ccccc23)cc1 nan
16189382 52215 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 4 5.0 Cc1cccc(N(C)C(=O)c2cc3c(O)nc4ccc(C)cc4c3s2)c1 nan
CHEMBL1588813 52215 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 4 5.0 Cc1cccc(N(C)C(=O)c2cc3c(O)nc4ccc(C)cc4c3s2)c1 nan
5770860 52257 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 2 6 2.4 CCOC(=O)CNC(=O)c1sc(NC(=O)/C=C/c2ccccc2)nc1C nan
CHEMBL1589172 52257 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 2 6 2.4 CCOC(=O)CNC(=O)c1sc(NC(=O)/C=C/c2ccccc2)nc1C nan
2428876 52260 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 4 2.7 O=C(COc1ccc2ccccc2c1)Nc1cccc2c1C(=O)NC2=O nan
CHEMBL1589183 52260 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 4 2.7 O=C(COc1ccc2ccccc2c1)Nc1cccc2c1C(=O)NC2=O nan
16007870 52343 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 8 1 4 4.9 Cc1ccc(CCNC(=O)CSCc2nc(-c3ccc(C)cc3)oc2C)cc1 nan
CHEMBL1589908 52343 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 8 1 4 4.9 Cc1ccc(CCNC(=O)CSCc2nc(-c3ccc(C)cc3)oc2C)cc1 nan
6418319 52360 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 5.7 O=C(CSc1nnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1)NC1CCCC1 nan
CHEMBL1590097 52360 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 5.7 O=C(CSc1nnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1)NC1CCCC1 nan
16025990 52371 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 2.2 Cc1c(Cl)cccc1NC(=O)c1cnc2sc(N3CCOCC3)nn2c1=O nan
CHEMBL1590252 52371 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 2.2 Cc1c(Cl)cccc1NC(=O)c1cnc2sc(N3CCOCC3)nn2c1=O nan
16030611 52388 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 0 5 5.3 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)N2CCCc3ccccc32)c1 nan
CHEMBL1590504 52388 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 0 5 5.3 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)N2CCCc3ccccc32)c1 nan
16009482 52389 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 7 3.9 COc1ccccc1C(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
CHEMBL1590536 52389 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 7 3.9 COc1ccccc1C(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
16015095 52390 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 8 1 6 5.5 CCOc1ccccc1NC(=O)c1sc(-n2nc(C)c(CCC(C)C)c2C)nc1C nan
CHEMBL1590548 52390 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 8 1 6 5.5 CCOc1ccccc1NC(=O)c1sc(-n2nc(C)c(CCC(C)C)c2C)nc1C nan
16019575 52398 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 5 1 9 4.6 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
CHEMBL1590659 52398 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 5 1 9 4.6 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
4249793 52405 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 2 4 1.8 COc1ccccc1C(=O)Nc1ccc2c(c1)C(=O)NC2=O nan
CHEMBL1590747 52405 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 2 4 1.8 COc1ccccc1C(=O)Nc1ccc2c(c1)C(=O)NC2=O nan
16016850 52413 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 2 3 5.9 COc1ccc2c(Sc3ccccc3)c(C(=O)NCC(C)c3ccccc3)[nH]c2c1 nan
CHEMBL1590842 52413 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 2 3 5.9 COc1ccc2c(Sc3ccccc3)c(C(=O)NCC(C)c3ccccc3)[nH]c2c1 nan
16025801 52447 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 7 1 7 2.9 COc1cccc(CNc2nccn(-c3ccc(OC)c(OC)c3)c2=O)c1 nan
CHEMBL1591265 52447 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 7 1 7 2.9 COc1cccc(CNc2nccn(-c3ccc(OC)c(OC)c3)c2=O)c1 nan
7533419 52487 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 8 1 6 3.5 CCOc1ccc(-c2nnc(SCC(=O)NCc3ccccc3)o2)cc1 nan
CHEMBL1591699 52487 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 8 1 6 3.5 CCOc1ccc(-c2nnc(SCC(=O)NCc3ccccc3)o2)cc1 nan
16030248 52508 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 5 3.7 O=C(CSc1nnc(-c2ccccc2Cl)[nH]1)N1CCN(c2ccc(F)cc2)CC1 nan
CHEMBL1591982 52508 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 5 3.7 O=C(CSc1nnc(-c2ccccc2Cl)[nH]1)N1CCN(c2ccc(F)cc2)CC1 nan
16021788 52518 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 3.3 O=C(NCc1ccccc1)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
CHEMBL1592133 52518 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 3.3 O=C(NCc1ccccc1)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
16008534 52557 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 9 1 6 5.2 CCOC(=O)C(Cc1ccccc1)NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccc(C)c(C)c2)c1C nan
CHEMBL1592680 52557 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 9 1 6 5.2 CCOC(=O)C(Cc1ccccc1)NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccc(C)c(C)c2)c1C nan
16012042 52559 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 7 1 5 4.6 O=C(Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O)NCCc1ccc(Cl)cc1 nan
CHEMBL1592702 52559 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 7 1 5 4.6 O=C(Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O)NCCc1ccc(Cl)cc1 nan
15991036 52572 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 4 6.7 COc1ccc(Cl)cc1C(=O)Nc1ccc2oc(-c3ccc(C(C)(C)C)cc3)nc2c1 nan
CHEMBL1592855 52572 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 4 6.7 COc1ccc(Cl)cc1C(=O)Nc1ccc2oc(-c3ccc(C(C)(C)C)cc3)nc2c1 nan
16026106 52587 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 5 3.9 CC1=C(c2ccc(C(C)C)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccco2)CC1 nan
CHEMBL1593080 52587 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 5 3.9 CC1=C(c2ccc(C(C)C)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccco2)CC1 nan
16009361 52590 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 7 1 6 4.3 CCOc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1593099 52590 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 7 1 6 4.3 CCOc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
16030919 52595 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.7 CCc1ccc(NC(=O)CSc2ccc3nc(-c4ccc(OC)cc4)cn3n2)cc1 nan
CHEMBL1593184 52595 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.7 CCc1ccc(NC(=O)CSc2ccc3nc(-c4ccc(OC)cc4)cn3n2)cc1 nan
16033356 52600 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 4 5.5 COc1ccc(CC(=O)Nc2ccc(-c3nc4ccccc4s3)c(C)c2)cc1 nan
CHEMBL1593249 52600 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 4 5.5 COc1ccc(CC(=O)Nc2ccc(-c3nc4ccccc4s3)c(C)c2)cc1 nan
16015767 52629 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 7 0 5 3.9 Cc1ccc(CN(C(=O)COc2ccccc2[N+](=O)[O-])c2ccccn2)cc1 nan
CHEMBL1593732 52629 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 7 0 5 3.9 Cc1ccc(CN(C(=O)COc2ccccc2[N+](=O)[O-])c2ccccn2)cc1 nan
15990880 52634 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 3 5.6 Cc1ccc(Nc2cc(C(=O)NCCc3ccccc3)c3ccccc3n2)c(C)c1 nan
CHEMBL1593807 52634 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 3 5.6 Cc1ccc(Nc2cc(C(=O)NCCc3ccccc3)c3ccccc3n2)c(C)c1 nan
3623411 52646 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 4 6.0 CCOc1ccc(Sc2cc(C(=O)NCc3ccc(C)cc3)c3ccccc3n2)cc1 nan
CHEMBL1593971 52646 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 4 6.0 CCOc1ccc(Sc2cc(C(=O)NCc3ccc(C)cc3)c3ccccc3n2)cc1 nan
16030473 52717 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.5 Cc1ccc2nc(COc3cccc(NC(=O)c4cccc(Cl)c4)c3)cc(=O)n2c1 nan
CHEMBL1594609 52717 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.5 Cc1ccc2nc(COc3cccc(NC(=O)c4cccc(Cl)c4)c3)cc(=O)n2c1 nan
2328630 52731 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 6 1 6 2.9 CCOC(=O)c1c(C)[nH]c(C(=O)CSc2nccc(C)n2)c1C nan
CHEMBL1594696 52731 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 6 1 6 2.9 CCOC(=O)c1c(C)[nH]c(C(=O)CSc2nccc(C)n2)c1C nan
16027342 52785 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 4 4.1 Cc1cc(=O)n(Cc2cccc(F)c2)c2c1c(C)nn2-c1cccc(F)c1 nan
CHEMBL1595156 52785 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 4 4.1 Cc1cc(=O)n(Cc2cccc(F)c2)c2c1c(C)nn2-c1cccc(F)c1 nan
16021494 52792 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 4 3.9 CSc1ncc(C(=O)NCc2ccc(F)cc2)c(-c2ccccc2)n1 nan
CHEMBL1595189 52792 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 4 3.9 CSc1ncc(C(=O)NCc2ccc(F)cc2)c(-c2ccccc2)n1 nan
4584398 52894 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 2 1 2 4.7 Cn1c(C(=O)Nc2ccc(Cl)cc2)cc2cc(Cl)ccc21 nan
CHEMBL1596148 52894 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 2 1 2 4.7 Cn1c(C(=O)Nc2ccc(Cl)cc2)cc2cc(Cl)ccc21 nan
16016964 52926 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 4 4.7 Cc1cc(C)c2c(-n3cccc3)c(C(=O)NCCc3ccccc3)sc2n1 nan
CHEMBL1596415 52926 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 4 4.7 Cc1cc(C)c2c(-n3cccc3)c(C(=O)NCCc3ccccc3)sc2n1 nan
891582 52951 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 0 5 3.8 Cc1cccc(-n2ncc3c(N4CCc5ccccc54)ncnc32)c1 nan
CHEMBL1596656 52951 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 0 5 3.8 Cc1cccc(-n2ncc3c(N4CCc5ccccc54)ncnc32)c1 nan
2138637 52954 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 2 6 3.5 CC(=O)NCCNc1nc2c(-c3cccc(C(F)(F)F)c3)nnn2c2ccccc12 nan
CHEMBL1596664 52954 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 2 6 3.5 CC(=O)NCCNc1nc2c(-c3cccc(C(F)(F)F)c3)nnn2c2ccccc12 nan
4062063 53020 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 3 8 -0.4 CN(CCO)S(=O)(=O)c1ccc2c(c1)C(=NN)c1cc(S(=O)(=O)N(C)CCO)ccc1-2 nan
CHEMBL1597275 53020 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 3 8 -0.4 CN(CCO)S(=O)(=O)c1ccc2c(c1)C(=NN)c1cc(S(=O)(=O)N(C)CCO)ccc1-2 nan
1611638 53113 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 2 10 3.2 CCOC(=O)Cc1csc(NC(=O)CSc2nc(N)c3c(C)c(C)sc3n2)n1 nan
CHEMBL1598169 53113 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 2 10 3.2 CCOC(=O)Cc1csc(NC(=O)CSc2nc(N)c3c(C)c(C)sc3n2)n1 nan
16010773 53116 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.2 COc1ccc(Cn2c(=O)c3cccnc3n(CC(=O)Nc3c(C)cc(C)cc3C)c2=O)cc1 nan
CHEMBL1598197 53116 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.2 COc1ccc(Cn2c(=O)c3cccnc3n(CC(=O)Nc3c(C)cc(C)cc3C)c2=O)cc1 nan
2958808 53118 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 2 4 3.7 Cc1nc(NC(=S)NC(=O)COc2ccccc2Cl)ccc1Br nan
CHEMBL1598226 53118 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 2 4 3.7 Cc1nc(NC(=S)NC(=O)COc2ccccc2Cl)ccc1Br nan
921716 53176 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 4 4.9 Cc1ccc(O)c(C2=Nc3ccccc3N=C(c3ccco3)C2)c1 nan
CHEMBL1598745 53176 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 4 4.9 Cc1ccc(O)c(C2=Nc3ccccc3N=C(c3ccco3)C2)c1 nan
3284133 53184 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 10 2 6 4.2 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCN(C(C)C)C3)cc1 nan
CHEMBL1598836 53184 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 10 2 6 4.2 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCN(C(C)C)C3)cc1 nan
7326265 53235 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 2 5 3.5 CC(=O)Nc1ccc(C(=O)Nc2nnc(CCc3ccccc3)s2)cc1 nan
CHEMBL1599247 53235 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 2 5 3.5 CC(=O)Nc1ccc(C(=O)Nc2nnc(CCc3ccccc3)s2)cc1 nan
16009345 53250 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 5 0 6 4.0 COc1cccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1 nan
CHEMBL1599358 53250 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 5 0 6 4.0 COc1cccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1 nan
16024944 53289 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 2 4 4.8 Cc1cccc(N2CCN(c3ccc(C(=O)O)cc3NC(=O)c3ccccc3F)CC2C)c1 nan
CHEMBL1599731 53289 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 2 4 4.8 Cc1cccc(N2CCN(c3ccc(C(=O)O)cc3NC(=O)c3ccccc3F)CC2C)c1 nan
6536107 53334 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 5.2 Cc1ccc(-c2csc(/C=C3\SC(C)C(=O)N3CC(=O)Nc3ccccc3F)n2)cc1 nan
CHEMBL1600183 53334 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 5.2 Cc1ccc(-c2csc(/C=C3\SC(C)C(=O)N3CC(=O)Nc3ccccc3F)n2)cc1 nan
733979 53344 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 1 4 2.5 CC(=O)c1ccc(NC2=NS(=O)(=O)c3ccccc32)cc1 nan
CHEMBL1600285 53344 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 1 4 2.5 CC(=O)c1ccc(NC2=NS(=O)(=O)c3ccccc32)cc1 nan
2999237 53349 3 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 6 1 6 2.8 CCCCn1c(-c2ccsc2)nc2c1c(=O)[nH]c(=O)n2CCC nan
CHEMBL1600302 53349 3 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 6 1 6 2.8 CCCCn1c(-c2ccsc2)nc2c1c(=O)[nH]c(=O)n2CCC nan
3946061 53391 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 7 3.2 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NCc5ccccc5)cnc4c3cc2CO1 nan
CHEMBL1600688 53391 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 7 3.2 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NCc5ccccc5)cnc4c3cc2CO1 nan
16019821 53394 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 2 6 3.4 CCOc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
CHEMBL1600701 53394 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 2 6 3.4 CCOc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
648853 53402 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.2 Cc1ccc(C(=O)Nc2nc3ccccc3c(=O)s2)cc1 nan
CHEMBL1600749 53402 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.2 Cc1ccc(C(=O)Nc2nc3ccccc3c(=O)s2)cc1 nan
1326969 53462 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 4 5.1 Cc1ccc(OCC(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)c(C)c1 nan
CHEMBL1601297 53462 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 4 5.1 Cc1ccc(OCC(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)c(C)c1 nan
20949434 53465 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 4 2 6 1.7 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CC(=O)N4)CC2)cc1 nan
CHEMBL1601336 53465 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 4 2 6 1.7 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CC(=O)N4)CC2)cc1 nan
16015783 53476 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 6 1 6 6.2 COc1ccc(-c2cc(C(=O)Nc3c(C(=O)c4ccc(Cl)cc4)oc4ccccc34)no2)cc1 nan
CHEMBL1601476 53476 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 6 1 6 6.2 COc1ccc(-c2cc(C(=O)Nc3c(C(=O)c4ccc(Cl)cc4)oc4ccccc34)no2)cc1 nan
3579351 53516 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 0 7 4.2 COc1ccc(-n2c(SCC(=O)C(C)(C)C)nc3ccsc3c2=O)cc1 nan
CHEMBL1601921 53516 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 0 7 4.2 COc1ccc(-n2c(SCC(=O)C(C)(C)C)nc3ccsc3c2=O)cc1 nan
16034721 53582 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 2 7 4.3 Cc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccccc4)cc3nc2s1 nan
CHEMBL1602585 53582 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 2 7 4.3 Cc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccccc4)cc3nc2s1 nan
3938730 53622 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 2 4 6.4 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)NCc3ccc(Cl)cc3)sc2n1 nan
CHEMBL1602945 53622 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 2 4 6.4 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)NCc3ccc(Cl)cc3)sc2n1 nan
3343394 53702 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 2 1 6 5.1 CC1(C)Cc2c(sc3c2c(N)nc(=S)n3Cc2ccc(Br)cc2)CO1 nan
CHEMBL1603651 53702 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 2 1 6 5.1 CC1(C)Cc2c(sc3c2c(N)nc(=S)n3Cc2ccc(Br)cc2)CO1 nan
5223767 53703 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 4 3.3 Cc1cc2cc(CNC(=O)Cc3ccc([N+](=O)[O-])cc3)ccc2n1C nan
CHEMBL1603656 53703 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 4 3.3 Cc1cc2cc(CNC(=O)Cc3ccc([N+](=O)[O-])cc3)ccc2n1C nan
16030948 53720 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.1 O=C(CSc1ccc2nc(-c3ccccc3)cn2n1)Nc1ccccc1C(F)(F)F nan
CHEMBL1603757 53720 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.1 O=C(CSc1ccc2nc(-c3ccccc3)cn2n1)Nc1ccccc1C(F)(F)F nan
2791873 53752 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 5 2 5 3.0 CCOC(=O)c1cnc2ccc(Br)cc2c1NCC(C)O nan
CHEMBL1603951 53752 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 5 2 5 3.0 CCOC(=O)c1cnc2ccc(Br)cc2c1NCC(C)O nan
16014801 53865 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 4.1 Cc1cccc(CSc2nc(=O)c3c(n2C)NC(=O)CC3c2cc(F)cc(F)c2)c1 nan
CHEMBL1605009 53865 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 4.1 Cc1cccc(CSc2nc(=O)c3c(n2C)NC(=O)CC3c2cc(F)cc(F)c2)c1 nan
135435545 53880 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 2 2 4 2.3 NC1=C(c2nc3ccccc3[nH]2)C(=O)CN1c1ccccc1 nan
CHEMBL1605162 53880 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 2 2 4 2.3 NC1=C(c2nc3ccccc3[nH]2)C(=O)CN1c1ccccc1 nan
1511904 53895 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 4 3.8 O=C(O)c1cn(-c2ccc(N3CCCC3)c(F)c2)c2c(F)c(F)c(F)cc2c1=O nan
CHEMBL1605292 53895 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 4 3.8 O=C(O)c1cn(-c2ccc(N3CCCC3)c(F)c2)c2c(F)c(F)c(F)cc2c1=O nan
1961588 53974 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 3 0 6 4.9 Cn1c2ccccc2c(=O)c2c(=O)n(Cc3ccco3)c(-c3ccc(Cl)cc3Cl)nc21 nan
CHEMBL1605870 53974 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 3 0 6 4.9 Cn1c2ccccc2c(=O)c2c(=O)n(Cc3ccco3)c(-c3ccc(Cl)cc3Cl)nc21 nan
16001902 53989 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 6 3.3 Cc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3cccc4nsnc34)C2)cc1C nan
CHEMBL1605982 53989 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 6 3.3 Cc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3cccc4nsnc34)C2)cc1C nan
16031132 54077 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 5 4.5 CN(C)c1ccc(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)cc1 nan
CHEMBL1606681 54077 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 5 4.5 CN(C)c1ccc(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)cc1 nan
2931173 54083 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 2 3 4.9 CCCCn1c(N=C(S)Nc2ccccc2)nc2ccccc21 nan
CHEMBL1606716 54083 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 2 3 4.9 CCCCn1c(N=C(S)Nc2ccccc2)nc2ccccc21 nan
1481761 54199 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 5 4.1 COc1ccc(-c2c(C)nc3c(-c4ccc(F)cc4)cnn3c2N)cc1 nan
CHEMBL1607515 54199 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 5 4.1 COc1ccc(-c2c(C)nc3c(-c4ccc(F)cc4)cnn3c2N)cc1 nan
16030158 54235 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 7 3.2 Cc1nn(CC(=O)NCc2ccc(N(C)C)cc2)c(=O)c2c(C)n(-c3ccc(Cl)cc3)nc12 nan
CHEMBL1607845 54235 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 7 3.2 Cc1nn(CC(=O)NCc2ccc(N(C)C)cc2)c(=O)c2c(C)n(-c3ccc(Cl)cc3)nc12 nan
786570 54249 39 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 1 1 3 3.8 O=c1c2cc(Br)ccc2[nH]c(=S)n1-c1ccccc1 nan
CHEMBL1608028 54249 39 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 1 1 3 3.8 O=c1c2cc(Br)ccc2[nH]c(=S)n1-c1ccccc1 nan
744022 54346 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 4 1 4 3.8 COCc1cc(C)nc(Nc2ccc(C)c(C)c2)c1C#N nan
CHEMBL1608862 54346 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 4 1 4 3.8 COCc1cc(C)nc(Nc2ccc(C)c(C)c2)c1C#N nan
20868577 54363 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nc5ccccc5c4o3)CC2)cc1 nan
CHEMBL1609003 54363 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nc5ccccc5c4o3)CC2)cc1 nan
16015522 54369 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 3.5 COc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2)cc1 nan
CHEMBL1609032 54369 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 3.5 COc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2)cc1 nan
3128209 54457 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 2 8 1.5 NS(=O)(=O)c1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1 nan
CHEMBL1609744 54457 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 2 8 1.5 NS(=O)(=O)c1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1 nan
16026888 54527 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 0 8 3.6 COc1ccccc1C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
CHEMBL1610338 54527 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 0 8 3.6 COc1ccccc1C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
16015736 54551 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 7 0 4 3.3 Cc1ccc(C(C)C)c(OCC(=O)N2CCN(CCc3ccncc3)CC2)c1 nan
CHEMBL1610516 54551 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 7 0 4 3.3 Cc1ccc(C(C)C)c(OCC(=O)N2CCN(CCc3ccncc3)CC2)c1 nan
2220915 54625 11 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 5 4.9 COc1ccc(CCNC(=O)c2cc(-c3ccccn3)nc3c(Cl)cccc23)cc1OC nan
CHEMBL1611237 54625 11 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 5 4.9 COc1ccc(CCNC(=O)c2cc(-c3ccccn3)nc3c(Cl)cccc23)cc1OC nan
16030297 54653 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 0 5 4.9 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)N1CCc2ccccc21 nan
CHEMBL1611407 54653 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 0 5 4.9 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)N1CCc2ccccc21 nan
903550 54697 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 4 1 5 2.5 CCOC(=O)c1sc(NC(=O)CC)c(C#N)c1C nan
CHEMBL1611829 54697 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 4 1 5 2.5 CCOC(=O)c1sc(NC(=O)CC)c(C#N)c1C nan
2804057 54725 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 206 0 2 2 3.1 Cc1c(C)c(C)c2[nH]c(S)nc2c1C nan
CHEMBL1612138 54725 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 206 0 2 2 3.1 Cc1c(C)c(C)c2[nH]c(S)nc2c1C nan
16019436 54792 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 3.6 Cc1ccc(C)c(CSc2ccc3nnc(CCNS(=O)(=O)c4ccccc4)n3n2)c1 nan
CHEMBL1612674 54792 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 3.6 Cc1ccc(C)c(CSc2ccc3nnc(CCNS(=O)(=O)c4ccccc4)n3n2)c1 nan
4152434 54806 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 1 5 5.7 CC(C)c1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
CHEMBL1612783 54806 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 1 5 5.7 CC(C)c1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
16034221 54842 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 1 7 1.1 CCOC(=O)N1CCN(S(=O)(=O)N2CCCC(C(=O)NCc3cc(OC)ccc3OC)C2)CC1 nan
CHEMBL1613162 54842 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 1 7 1.1 CCOC(=O)N1CCN(S(=O)(=O)N2CCCC(C(=O)NCc3cc(OC)ccc3OC)C2)CC1 nan
3238969 54846 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 1 4 5.6 O=C(Nc1ccc2oc(-c3ccccc3Cl)nc2c1)c1cncc(Br)c1 nan
CHEMBL1613230 54846 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 1 4 5.6 O=C(Nc1ccc2oc(-c3ccccc3Cl)nc2c1)c1cncc(Br)c1 nan
16033448 54857 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 1 4 4.8 Cc1cc(C)c(NC(=O)c2nc3ccccc3nc2N2CCCCC2)c(C)c1 nan
CHEMBL1613324 54857 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 1 4 4.8 Cc1cc(C)c(NC(=O)c2nc3ccccc3nc2N2CCCCC2)c(C)c1 nan
2138172 54862 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 6 1 6 3.1 C=CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)nc1C nan
CHEMBL1613374 54862 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 6 1 6 3.1 C=CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)nc1C nan
17585635 55142 5 None -11 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 1 3.8 Cn1cc(/C=C/c2cc[n+](C)cc2)c2cc(Cl)ccc21 nan
73401607 55142 5 None -11 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 1 3.8 Cn1cc(/C=C/c2cc[n+](C)cc2)c2cc(Cl)ccc21 nan
CHEMBL1311226 55142 5 None -11 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 1 3.8 Cn1cc(/C=C/c2cc[n+](C)cc2)c2cc(Cl)ccc21 nan
CHEMBL1617414 55142 5 None -11 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 1 3.8 Cn1cc(/C=C/c2cc[n+](C)cc2)c2cc(Cl)ccc21 nan
424003 55279 30 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 202 1 1 2 1.8 NCc1cc2c3c(c1)CCCN3CCC2 nan
CHEMBL1359356 55279 30 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 202 1 1 2 1.8 NCc1cc2c3c(c1)CCCN3CCC2 nan
CHEMBL1618556 55279 30 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 202 1 1 2 1.8 NCc1cc2c3c(c1)CCCN3CCC2 nan
719481 55289 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 4.5 COc1ccc(-n2cc(-c3ccc(Cl)cc3)nc2S)cc1 nan
CHEMBL1379055 55289 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 4.5 COc1ccc(-n2cc(-c3ccc(Cl)cc3)nc2S)cc1 nan
CHEMBL1618658 55289 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 4.5 COc1ccc(-n2cc(-c3ccc(Cl)cc3)nc2S)cc1 nan
1453026 55638 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 2 7 3.6 COc1ccc(C(=O)Nc2ccc(NC(=O)c3cc(OC)c(OC)c(OC)c3)cn2)cc1 nan
CHEMBL1442637 55638 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 2 7 3.6 COc1ccc(C(=O)Nc2ccc(NC(=O)c3cc(OC)c(OC)c(OC)c3)cn2)cc1 nan
CHEMBL1621750 55638 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 2 7 3.6 COc1ccc(C(=O)Nc2ccc(NC(=O)c3cc(OC)c(OC)c(OC)c3)cn2)cc1 nan
5044272 55887 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 7 4.8 CCN(CC)CCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1524152 55887 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 7 4.8 CCN(CC)CCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1623691 55887 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 7 4.8 CCN(CC)CCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
3149296 55919 6 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 2 0 3 6.1 CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2C)Sc2ccc3sccc3c21 nan
5768586 55919 6 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 2 0 3 6.1 CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2C)Sc2ccc3sccc3c21 nan
CHEMBL1508982 55919 6 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 2 0 3 6.1 CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2C)Sc2ccc3sccc3c21 nan
CHEMBL1623968 55919 6 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 2 0 3 6.1 CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2C)Sc2ccc3sccc3c21 nan
1956404 55945 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 7 3.5 COCCN1CCn2c(nc3cc(Nc4nnc(C)c5ccccc45)ccc32)C1 nan
CHEMBL1556245 55945 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 7 3.5 COCCN1CCn2c(nc3cc(Nc4nnc(C)c5ccccc45)ccc32)C1 nan
CHEMBL1624228 55945 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 7 3.5 COCCN1CCn2c(nc3cc(Nc4nnc(C)c5ccccc45)ccc32)C1 nan
3602384 56080 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 3 4.5 Cc1ccc(CNC(=O)c2cc3c(s2)CN(Cc2ccccc2)C3)cc1 nan
CHEMBL1602214 56080 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 3 4.5 Cc1ccc(CNC(=O)c2cc3c(s2)CN(Cc2ccccc2)C3)cc1 nan
CHEMBL1625426 56080 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 3 4.5 Cc1ccc(CNC(=O)c2cc3c(s2)CN(Cc2ccccc2)C3)cc1 nan
2151347 71952 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 0 4 3.3 C#CCn1/c(=N/C(=O)c2ccco2)sc2cccc(Cl)c21 nan
CHEMBL1973713 71952 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 0 4 3.3 C#CCn1/c(=N/C(=O)c2ccco2)sc2cccc(Cl)c21 nan
741794 72258 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 1 1 4 3.1 Cc1c(C(C)(C)C)s/c(=N/C(=O)c2ccccc2O)n1C nan
CHEMBL1983034 72258 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 1 1 4 3.1 Cc1c(C(C)(C)C)s/c(=N/C(=O)c2ccccc2O)n1C nan
9583974 72520 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 2 7 5.1 COc1cccc(/C=N/NC(=O)c2oc3nc(-c4ccccc4)cc(-c4ccco4)c3c2N)c1 nan
CHEMBL1991618 72520 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 2 7 5.1 COc1cccc(/C=N/NC(=O)c2oc3nc(-c4ccccc4)cc(-c4ccco4)c3c2N)c1 nan
135498048 72603 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 3 2 6 0.8 Cc1nonc1C(=O)N/N=C/c1ccc(O)cc1 nan
CHEMBL1994596 72603 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 3 2 6 0.8 Cc1nonc1C(=O)N/N=C/c1ccc(O)cc1 nan
1362920 95741 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(OCC(=O)Nc2ccc(-c3nc4cc(C)cc(C)c4o3)cc2)cc1 nan
CHEMBL258549 95741 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(OCC(=O)Nc2ccc(-c3nc4cc(C)cc(C)c4o3)cc2)cc1 nan
2150885 107590 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 0 5 3.3 COc1ccc(OC)c2c1s/c(=N\C(=O)C1CCCCC1)n2C nan
CHEMBL3189890 107590 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 0 5 3.3 COc1ccc(OC)c2c1s/c(=N\C(=O)C1CCCCC1)n2C nan
3604296 107752 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 0 7 2.1 CCOC(=O)Cn1/c(=N/C(=O)CSC(C)=O)sc2cc(F)ccc21 nan
CHEMBL3191753 107752 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 0 7 2.1 CCOC(=O)Cn1/c(=N/C(=O)CSC(C)=O)sc2cc(F)ccc21 nan
1389664 107948 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 0 8 3.2 COc1cc(/C=c2\sc3nc(=O)c(-c4ccccc4)nn3c2=O)ccc1OCCC(C)C nan
CHEMBL3193918 107948 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 0 8 3.2 COc1cc(/C=c2\sc3nc(=O)c(-c4ccccc4)nn3c2=O)ccc1OCCC(C)C nan
2321009 108022 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 1 0 4 3.4 Cc1ccc2c(c1)s/c(=N/C(=O)c1cccs1)n2C nan
CHEMBL3194826 108022 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 1 0 4 3.4 Cc1ccc2c(c1)s/c(=N/C(=O)c1cccs1)n2C nan
3245289 108027 11 None -31 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 0 8 2.0 CCOC(=O)Cn1/c(=N/C(=O)CSC(C)=O)sc2cc(OC)ccc21 nan
CHEMBL3194890 108027 11 None -31 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 0 8 2.0 CCOC(=O)Cn1/c(=N/C(=O)CSC(C)=O)sc2cc(OC)ccc21 nan
4668650 108299 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 1.5 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(N)(=O)=O)ccc21 nan
CHEMBL3197833 108299 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 1.5 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(N)(=O)=O)ccc21 nan
2150918 108354 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 3 0 6 3.0 COc1ccc(C)c2s/c(=N\C(=O)c3cccc(N4C(=O)CCC4=O)c3)n(C)c12 nan
CHEMBL3198311 108354 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 3 0 6 3.0 COc1ccc(C)c2s/c(=N\C(=O)c3cccc(N4C(=O)CCC4=O)c3)n(C)c12 nan
135460447 108367 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 3 3 6 1.9 Nc1c(Cl)ncnc1N/N=C/c1ccc(O)cc1 nan
CHEMBL3198494 108367 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 3 3 6 1.9 Nc1c(Cl)ncnc1N/N=C/c1ccc(O)cc1 nan
6184027 108646 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 12 1 9 0.8 COCCCn1c(=O)/c(=C\c2ccc(OC(F)F)c(OC)c2)s/c1=C(/C#N)C(=O)NCCOC nan
CHEMBL3207685 108646 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 12 1 9 0.8 COCCCn1c(=O)/c(=C\c2ccc(OC(F)F)c(OC)c2)s/c1=C(/C#N)C(=O)NCCOC nan
2150849 108678 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 0 7 3.3 COc1cc(C(=O)/N=c2\sc3c(C)ccc(OC)c3n2C)cc(OC)c1OC nan
CHEMBL3208227 108678 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 0 7 3.3 COc1cc(C(=O)/N=c2\sc3c(C)ccc(OC)c3n2C)cc(OC)c1OC nan
5122885 108807 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccccc2Br)n(C)c1C nan
CHEMBL3209816 108807 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccccc2Br)n(C)c1C nan
9631393 108900 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 4 3.2 O=C(N/N=C/c1ccc2nccnc2c1)c1ccc(Br)cc1 nan
CHEMBL3211205 108900 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 4 3.2 O=C(N/N=C/c1ccc2nccnc2c1)c1ccc(Br)cc1 nan
4128025 108914 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 0 6 2.4 COc1cccc(C(=O)/N=c2\sc3cc(S(C)(=O)=O)ccc3n2C)c1 nan
CHEMBL3211378 108914 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 0 6 2.4 COc1cccc(C(=O)/N=c2\sc3cc(S(C)(=O)=O)ccc3n2C)c1 nan
7161820 108934 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 5 2.7 CCOC(=O)Cn1/c(=N/C(=O)CC)sc2c(C)cc(C)cc21 nan
CHEMBL3211674 108934 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 5 2.7 CCOC(=O)Cn1/c(=N/C(=O)CC)sc2c(C)cc(C)cc21 nan
2150987 109144 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 0 5 2.5 CCCC(=O)/N=c1\sc2c(OC)ccc(OC)c2n1C nan
CHEMBL3214516 109144 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 0 5 2.5 CCCC(=O)/N=c1\sc2c(OC)ccc(OC)c2n1C nan
3213263 112584 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 0 7 3.1 COCC/N=C1\Sc2nc3cc4c(cc3cc2CN1CC1CCCO1)OCO4 nan
CHEMBL3197118 112584 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 0 7 3.1 COCC/N=C1\Sc2nc3cc4c(cc3cc2CN1CC1CCCO1)OCO4 nan
CHEMBL3302243 112584 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 0 7 3.1 COCC/N=C1\Sc2nc3cc4c(cc3cc2CN1CC1CCCO1)OCO4 nan
6540428 184840 1 None -37 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 4 1.9 CCC(CO)NC(=O)[C@@H]1C=C2c3cccc4c3c(cn4C)C[C@H]2N(C)C1 nan
CHEMBL3989558 184840 1 None -37 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 4 1.9 CCC(CO)NC(=O)[C@@H]1C=C2c3cccc4c3c(cn4C)C[C@H]2N(C)C1 nan
CHEMBL485253 184840 1 None -37 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 4 1.9 CCC(CO)NC(=O)[C@@H]1C=C2c3cccc4c3c(cn4C)C[C@H]2N(C)C1 nan
846186 193348 26 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 1 3 3 3.0 Cc1nc2ccc(-c3nc4cc(N)ccc4[nH]3)cc2[nH]1 nan
CHEMBL525103 193348 26 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 1 3 3 3.0 Cc1nc2ccc(-c3nc4cc(N)ccc4[nH]3)cc2[nH]1 nan
2850154 197873 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 1 2 1 2.1 CC1=CC(c2ccccc2)NC(=S)N1 nan
CHEMBL572806 197873 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 1 2 1 2.1 CC1=CC(c2ccccc2)NC(=S)N1 nan
138884 199979 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 2 4 4.2 COc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(OC)c3)c2)c1 nan
CHEMBL595273 199979 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 2 4 4.2 COc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(OC)c3)c2)c1 nan
16020583 202355 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 0 5 4.2 Cn1cc(S(=O)(=O)c2cccc(Cl)c2)c(=O)c2cc(F)c(N3CCCCC3)cc21 nan
CHEMBL610622 202355 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 0 5 4.2 Cn1cc(S(=O)(=O)c2cccc(Cl)c2)c(=O)c2cc(F)c(N3CCCCC3)cc21 nan
1361408 21365 9 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 4 6.1 O=C(Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1)c1cc2ccccc2o1 nan
CHEMBL1314585 21365 9 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 4 6.1 O=C(Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1)c1cc2ccccc2o1 nan
1369231 21490 8 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 2 5 5.5 O=C(COc1ccc(Cl)cc1)Nc1ccc(-c2nc3cc(Cl)ccc3o2)c(O)c1 nan
CHEMBL1316173 21490 8 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 2 5 5.5 O=C(COc1ccc(Cl)cc1)Nc1ccc(-c2nc3cc(Cl)ccc3o2)c(O)c1 nan
16033420 21885 3 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1ccc(NC(=O)c2nc3ccccc3n(C)c2=O)cc1 nan
CHEMBL1320318 21885 3 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1ccc(NC(=O)c2nc3ccccc3n(C)c2=O)cc1 nan
16019599 22376 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 1 8 4.5 Cc1ccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)c(C)c1 nan
CHEMBL1324615 22376 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 1 8 4.5 Cc1ccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)c(C)c1 nan
16033879 22445 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 8 3.2 CCOC(=O)c1ccc(Nc2nn3c(=O)c4ccccc4nc3s2)cc1 nan
CHEMBL1325210 22445 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 8 3.2 CCOC(=O)c1ccc(Nc2nn3c(=O)c4ccccc4nc3s2)cc1 nan
1115824 23173 15 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1ccc(Cl)cc1 nan
CHEMBL1331382 23173 15 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1ccc(Cl)cc1 nan
460749 23517 8 None -11 6 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 1 0 7 0.7 Cn1nc(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)nc1-2 nan
CHEMBL1334062 23517 8 None -11 6 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 1 0 7 0.7 Cn1nc(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)nc1-2 nan
16746586 24501 0 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 3 8 0.2 CCCN=C1C(=O)C2=C(C(O)=C1C)N1CC3NC3[C@@]1(OC)C2COC(N)=O nan
CHEMBL1342436 24501 0 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 3 8 0.2 CCCN=C1C(=O)C2=C(C(O)=C1C)N1CC3NC3[C@@]1(OC)C2COC(N)=O nan
2128809 27014 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 5 1 6 3.2 Cc1cc(C)c(C(=O)CSc2nnc(O)n2C2CC2)cc1C nan
CHEMBL1365084 27014 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 5 1 6 3.2 Cc1cc(C)c(C(=O)CSc2nnc(O)n2C2CC2)cc1C nan
15988395 27142 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 2 2 3 3.4 CC1(C)CC(=O)c2cc(C(=O)Nc3ccc(Cl)cc3)c(=O)[nH]c2C1 nan
CHEMBL1366158 27142 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 2 2 3 3.4 CC1(C)CC(=O)c2cc(C(=O)Nc3ccc(Cl)cc3)c(=O)[nH]c2C1 nan
2168191 28048 14 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 5 5.8 Cc1sc(NC(=O)C2c3ccccc3Oc3ccccc32)c(C(=O)OC(C)C)c1C nan
CHEMBL1372901 28048 14 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 5 5.8 Cc1sc(NC(=O)C2c3ccccc3Oc3ccccc32)c(C(=O)OC(C)C)c1C nan
4578108 29064 7 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 2 5 2.4 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc2ncsc2c1 nan
CHEMBL1381180 29064 7 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 2 5 2.4 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc2ncsc2c1 nan
15988012 29972 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1388847 29972 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
16024702 32270 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 9 1 7 4.3 COCCn1c(SCC(=O)c2ccc(C)cc2C)nc2cc(C(=O)NC3CCCC3)ccc2c1=O nan
CHEMBL1410231 32270 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 9 1 7 4.3 COCCn1c(SCC(=O)c2ccc(C)cc2C)nc2cc(C(=O)NC3CCCC3)ccc2c1=O nan
16025307 33164 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 4.9 COc1ccccc1CNC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
CHEMBL1417794 33164 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 4.9 COc1ccccc1CNC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
4658659 35348 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 5 4.9 CCOC(=O)CSc1nc(-c2ccc(Cl)cc2)cc(C(F)(F)F)c1C#N nan
CHEMBL1437587 35348 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 5 4.9 CCOC(=O)CSc1nc(-c2ccc(Cl)cc2)cc(C(F)(F)F)c1C#N nan
16018194 40590 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 6 1 4 4.1 O=C(CCCn1c(=O)c2cccn2c2ccccc21)NCc1ccccc1Br nan
CHEMBL1483956 40590 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 6 1 4 4.1 O=C(CCCn1c(=O)c2cccn2c2ccccc21)NCc1ccccc1Br nan
1046621 40664 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 3 1 6 5.4 Cc1c(Cl)cccc1NC(=O)c1cc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2n1 nan
CHEMBL1484483 40664 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 3 1 6 5.4 Cc1c(Cl)cccc1NC(=O)c1cc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2n1 nan
16025305 44091 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 4.9 COc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
CHEMBL1515325 44091 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 4.9 COc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
2119988 44576 15 None 2 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 6 4.7 CCOC(=O)c1sc2nc(Cc3ccc(Cl)cc3)nc(S)c2c1C nan
CHEMBL1520325 44576 15 None 2 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 6 4.7 CCOC(=O)c1sc2nc(Cc3ccc(Cl)cc3)nc(S)c2c1C nan
3368526 47168 16 None 2 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 1 6 3.9 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Br)cc2)o1 nan
CHEMBL1543365 47168 16 None 2 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 1 6 3.9 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Br)cc2)o1 nan
16020714 52344 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 0 6 3.8 CCN(CC)c1cc2c(cc1F)c(=O)c(S(=O)(=O)c1ccc(OC)cc1)cn2CC nan
CHEMBL1589919 52344 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 0 6 3.8 CCN(CC)c1cc2c(cc1F)c(=O)c(S(=O)(=O)c1ccc(OC)cc1)cn2CC nan
1164393 52362 10 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 6 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
CHEMBL1590134 52362 10 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 6 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
2254266 108047 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 0 6 4.7 C=CCN1C(=O)/C(=C2/Sc3ccc(OC)cc3N2C)S/C1=N\Cc1ccccc1 nan
CHEMBL3195210 108047 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 0 6 4.7 C=CCN1C(=O)/C(=C2/Sc3ccc(OC)cc3N2C)S/C1=N\Cc1ccccc1 nan
7424526 40373 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 2 7 0.0 COCCNC(=O)C(=O)Nc1c2c(nn1-c1ccccc1)CS(=O)(=O)C2 nan
CHEMBL1482031 40373 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 2 7 0.0 COCCNC(=O)C(=O)Nc1c2c(nn1-c1ccccc1)CS(=O)(=O)C2 nan
4890321 19676 8 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 2 6 3.7 Cc1ccc(NC2=NC(c3ccc(F)cc3)n3c(nc(C)cc3=O)N2)c(C)c1 nan
CHEMBL1300954 19676 8 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 2 6 3.7 Cc1ccc(NC2=NC(c3ccc(F)cc3)n3c(nc(C)cc3=O)N2)c(C)c1 nan
7119211 21440 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 4.6 COc1ccc(-c2nc(CCNC(=O)c3c(F)cccc3Cl)cs2)cc1 nan
CHEMBL1315624 21440 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 4.6 COc1ccc(-c2nc(CCNC(=O)c3c(F)cccc3Cl)cs2)cc1 nan
16028928 21567 5 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 2 6 3.0 COC(=O)c1ccc(NC(=O)C(=O)NCCc2csc(-c3ccc(F)cc3)n2)cc1 nan
CHEMBL1317331 21567 5 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 2 6 3.0 COC(=O)c1ccc(NC(=O)C(=O)NCCc2csc(-c3ccc(F)cc3)n2)cc1 nan
16009640 22145 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 1 7 4.5 CCOc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1322592 22145 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 1 7 4.5 CCOc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
15988993 22379 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 4 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)cc1 nan
CHEMBL1324637 22379 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 4 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)cc1 nan
682221 25351 20 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 4 3 8 0.2 CC(C)OC(=O)CNc1nnc(S)nc1O nan
CHEMBL1349621 25351 20 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 4 3 8 0.2 CC(C)OC(=O)CNc1nnc(S)nc1O nan
16009655 26048 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 4.4 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1355671 26048 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 4.4 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
16019300 27187 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 6 1 10 4.6 COc1cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)cc(OC)c1 nan
CHEMBL1366490 27187 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 6 1 10 4.6 COc1cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)cc(OC)c1 nan
16024750 29208 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 0 5 3.7 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4)CC3)ccc2c1)N1CCCCC1 nan
CHEMBL1382499 29208 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 0 5 3.7 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4)CC3)ccc2c1)N1CCCCC1 nan
5302633 30929 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 6 2 5 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2OC)cc1 nan
CHEMBL1398493 30929 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 6 2 5 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2OC)cc1 nan
16009653 35598 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 4 5.2 Cc1ccccc1OCC(=O)Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12 nan
CHEMBL1439712 35598 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 4 5.2 Cc1ccccc1OCC(=O)Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12 nan
3522635 38988 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 2.8 CCN(CC)S(=O)(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(=O)c3ccccc3o2)c1 nan
CHEMBL1468421 38988 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 2.8 CCN(CC)S(=O)(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(=O)c3ccccc3o2)c1 nan
16018176 39980 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.2 COc1ccc(CNC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)cc1 nan
CHEMBL1478735 39980 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.2 COc1ccc(CNC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)cc1 nan
3432810 40137 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 2 4 5.7 O=C(Nc1ccc(-c2nc3ccccc3s2)c(O)c1)c1ccc(Br)cc1 nan
CHEMBL1479998 40137 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 2 4 5.7 O=C(Nc1ccc(-c2nc3ccccc3s2)c(O)c1)c1ccc(Br)cc1 nan
1234246 41317 10 None -1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 1 1 5 3.0 Cc1ccc(-n2nc3c(S)nnc(C)c3c2C)cc1 nan
CHEMBL1489869 41317 10 None -1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 1 1 5 3.0 Cc1ccc(-n2nc3c(S)nnc(C)c3c2C)cc1 nan
6800739 44523 3 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 4.6 CCc1ccc2n(-c3ccc(OC)cc3)c([S-])c(C(=O)Nc3cc(C)cc(C)c3)[n+]2c1 nan
CHEMBL1519802 44523 3 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 4.6 CCc1ccc2n(-c3ccc(OC)cc3)c([S-])c(C(=O)Nc3cc(C)cc(C)c3)[n+]2c1 nan
1744296 48361 24 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 4 6.7 N#Cc1c(-c2ccccc2)cc(-c2ccccc2)nc1SCC(=O)Nc1ccc(Cl)cc1 nan
CHEMBL1555056 48361 24 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 4 6.7 N#Cc1c(-c2ccccc2)cc(-c2ccccc2)nc1SCC(=O)Nc1ccc(Cl)cc1 nan
15988419 52515 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 2 3 3.5 CC1(C)CC(=O)c2cc(C(=O)Nc3ccc(Br)cc3)c(=O)[nH]c2C1 nan
CHEMBL1592108 52515 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 2 3 3.5 CC1(C)CC(=O)c2cc(C(=O)Nc3ccc(Br)cc3)c(=O)[nH]c2C1 nan
1863779 72205 15 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 2 8 2.4 CC1=CC=CN2C(=O)C(=C\c3sc(S)nc3O)/C(=N/CCCN3CCOCC3)N=C12 nan
CHEMBL1981539 72205 15 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 2 8 2.4 CC1=CC=CN2C(=O)C(=C\c3sc(S)nc3O)/C(=N/CCCN3CCOCC3)N=C12 nan
755656 172666 49 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 1 3 4.4 O=C(O)c1cc(-c2cccs2)nc2ccc(Br)cc12 nan
CHEMBL450135 172666 49 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 1 3 4.4 O=C(O)c1cc(-c2cccs2)nc2ccc(Br)cc12 nan
5808 176756 23 None -1 2 Human 6.3 pPotency = 6.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(C)NC[C@@H](O)c1ccc(O)c(O)c1 nan
CHEMBL1257092 176756 23 None -1 2 Human 6.3 pPotency = 6.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(C)NC[C@@H](O)c1ccc(O)c(O)c1 nan
CHEMBL460574 176756 23 None -1 2 Human 6.3 pPotency = 6.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(C)NC[C@@H](O)c1ccc(O)c(O)c1 nan
4905097 26907 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 6 1 5 2.2 CCCC(=O)Nc1ccc2c(c1)nc1n2CCN(CCOC)C1 nan
CHEMBL1364140 26907 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 6 1 5 2.2 CCCC(=O)Nc1ccc2c(c1)nc1n2CCN(CCOC)C1 nan
995260 31037 13 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 1 3 5.3 CCc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2C)s1 nan
CHEMBL1399507 31037 13 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 1 3 5.3 CCc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2C)s1 nan
15990423 32226 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 5 5.3 CCOc1ccccc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1409911 32226 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 5 5.3 CCOc1ccccc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
16024826 32901 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccc(F)cc5)CC4)ccc3c2)CC1 nan
CHEMBL1415463 32901 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccc(F)cc5)CC4)ccc3c2)CC1 nan
3242125 38904 4 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 1.7 COc1ccc(OC)c(CNC(=O)C2CCN(C(=O)N(C)C)CC2)c1 nan
CHEMBL1467628 38904 4 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 1.7 COc1ccc(OC)c(CNC(=O)C2CCN(C(=O)N(C)C)CC2)c1 nan
3501359 42730 17 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 8 2.6 COc1ccc(CNC(=O)c2cc3c(=O)n4cccc(C)c4nc3n(CC3CCCO3)c2=N)cc1 nan
CHEMBL1501993 42730 17 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 8 2.6 COc1ccc(CNC(=O)c2cc3c(=O)n4cccc(C)c4nc3n(CC3CCCO3)c2=N)cc1 nan
1234242 46540 3 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 6 3.1 CCOc1ccc(-n2nc3c(S)nnc(C)c3c2C)cc1 nan
CHEMBL1538068 46540 3 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 6 3.1 CCOc1ccc(-n2nc3c(S)nnc(C)c3c2C)cc1 nan
20921619 23551 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 8 2.9 COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)c3ccc(C)cc3)s2)cc1OC nan
CHEMBL1334300 23551 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 8 2.9 COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)c3ccc(C)cc3)s2)cc1OC nan
16024792 25055 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 0 5 4.0 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5)CC4)ccc3c2)CC1 nan
CHEMBL1347118 25055 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 0 5 4.0 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5)CC4)ccc3c2)CC1 nan
5762489 25383 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 1 3 4.6 N#C/C(=C/c1ccc(OCc2ccccc2)cc1)C(=O)NC1CCCCC1 nan
CHEMBL1349947 25383 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 1 3 4.6 N#C/C(=C/c1ccc(OCc2ccccc2)cc1)C(=O)NC1CCCCC1 nan
652632 26965 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 8 0 8 3.7 COc1cccc(C(=O)CSc2nnc(-c3cc(OC)cc(OC)c3)o2)c1 nan
CHEMBL1364667 26965 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 8 0 8 3.7 COc1cccc(C(=O)CSc2nnc(-c3cc(OC)cc(OC)c3)o2)c1 nan
4137748 27398 1 None 3 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 2 1 4 4.0 Cc1cc(NC(=O)c2ccccc2F)nc2c1c(=O)oc1ccccc12 nan
CHEMBL1368254 27398 1 None 3 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 2 1 4 4.0 Cc1cc(NC(=O)c2ccccc2F)nc2c1c(=O)oc1ccccc12 nan
701063 28218 18 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 5 2.7 COc1ccc(Cl)cc1-c1nnc(S)o1 nan
CHEMBL1374054 28218 18 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 5 2.7 COc1ccc(Cl)cc1-c1nnc(S)o1 nan
16024750 29208 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 0 5 3.7 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4)CC3)ccc2c1)N1CCCCC1 nan
CHEMBL1382499 29208 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 0 5 3.7 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4)CC3)ccc2c1)N1CCCCC1 nan
1051489 29333 14 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(NC(=O)CSc2nc(-c3ccc(C)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1383601 29333 14 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(NC(=O)CSc2nc(-c3ccc(C)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
2185557 29675 9 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 0 6 3.7 COc1ccc(C(=O)/C=C2/Sc3cc4c(cc3N2C)OCO4)cc1 nan
CHEMBL1386474 29675 9 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 0 6 3.7 COc1ccc(C(=O)/C=C2/Sc3cc4c(cc3N2C)OCO4)cc1 nan
16017568 30633 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 2.9 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccccc3)s2)c1 nan
CHEMBL1394623 30633 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 2.9 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccccc3)s2)c1 nan
16025297 30668 10 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 582 8 1 8 5.3 COc1cc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc(OC)c1 nan
CHEMBL1395000 30668 10 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 582 8 1 8 5.3 COc1cc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc(OC)c1 nan
2092877 31190 6 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 6 3.1 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4CCCC4=O)cc3)sc2c1 nan
CHEMBL1400998 31190 6 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 6 3.1 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4CCCC4=O)cc3)sc2c1 nan
681250 33837 16 None 3 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 0 3 3.7 N#Cc1cc2c(nc1SCc1ccccc1)CCC2 nan
CHEMBL1423417 33837 16 None 3 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 0 3 3.7 N#Cc1cc2c(nc1SCc1ccccc1)CCC2 nan
2994363 37519 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 4 2.3 CN1C(=O)c2ccc(C(=O)Nc3ccc(Br)cn3)cc2C1=O nan
CHEMBL1456212 37519 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 4 2.3 CN1C(=O)c2ccc(C(=O)Nc3ccc(Br)cn3)cc2C1=O nan
54679694 38130 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 8 2 6 3.5 C=CCn1c(=O)c(C(=O)NCCc2ccc(Cl)cc2)c(O)c2cc(OC)c(OC)cc21 nan
CHEMBL1461466 38130 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 8 2 6 3.5 C=CCn1c(=O)c(C(=O)NCCc2ccc(Cl)cc2)c(O)c2cc(OC)c(OC)cc21 nan
16814136 38755 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 11 1.1 CCCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1466491 38755 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 11 1.1 CCCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
16017049 39659 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 4 0 6 4.4 CCC(C(=O)N1CCN(c2ccccc2F)CC1)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1475149 39659 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 4 0 6 4.4 CCC(C(=O)N1CCN(c2ccccc2F)CC1)n1nc(C)c2sc3ccccc3c2c1=O nan
655498 40586 4 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 7 1 5 3.5 CCOc1ccc2cc(C#N)c(SCC(=O)NC(C)CC)nc2c1 nan
CHEMBL1483885 40586 4 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 7 1 5 3.5 CCOc1ccc2cc(C#N)c(SCC(=O)NC(C)CC)nc2c1 nan
16019676 41028 1 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCCCC3)nnc12 nan
CHEMBL1487718 41028 1 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCCCC3)nnc12 nan
1305684 41040 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.5 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3F)n2)cc1 nan
CHEMBL1487797 41040 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.5 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3F)n2)cc1 nan
4008999 41130 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 4 6.7 CCCCOc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)cc2C)cc1 nan
CHEMBL1488396 41130 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 4 6.7 CCCCOc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)cc2C)cc1 nan
976779 41511 14 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 4 1 4 2.5 COc1ccc(S(=O)(=O)Nc2ccccn2)c(C)c1C nan
CHEMBL1491184 41511 14 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 4 1 4 2.5 COc1ccc(S(=O)(=O)Nc2ccccn2)c(C)c1C nan
1457998 42455 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 6 2.3 Cc1cc(C)n2c(SCC(=O)NC3CCCCC3)nnc2n1 nan
CHEMBL1499565 42455 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 6 2.3 Cc1cc(C)n2c(SCC(=O)NC3CCCCC3)nnc2n1 nan
1555503 43684 20 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 6 3 8 0.6 CCCCOC(=O)CNc1nnc(S)nc1O nan
CHEMBL1510408 43684 20 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 6 3 8 0.6 CCCCOC(=O)CNc1nnc(S)nc1O nan
1484666 43807 15 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 0 6 4.2 COc1ccc(Oc2nc(SC)nc3ccsc23)cc1 nan
CHEMBL1511350 43807 15 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 0 6 4.2 COc1ccc(Oc2nc(SC)nc3ccsc23)cc1 nan
23760140 44341 1 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 9 5 5 -1.6 CC(=O)N[C@@H](CC(=O)N[C@H](CCC(=O)O)C(=O)O)C(=O)O nan
CHEMBL1518212 44341 1 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 9 5 5 -1.6 CC(=O)N[C@@H](CC(=O)N[C@H](CCC(=O)O)C(=O)O)C(=O)O nan
4385342 44650 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 7 1 6 3.2 CCOC(=O)c1sc(NC(=O)CCc2ccc(OC)cc2)nc1C nan
CHEMBL1520883 44650 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 7 1 6 3.2 CCOC(=O)c1sc(NC(=O)CCc2ccc(OC)cc2)nc1C nan
2552702 46568 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 0 7 2.2 O=C(OCc1cc([N+](=O)[O-])cc2c1OCOC2)c1ccccn1 nan
CHEMBL1538293 46568 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 0 7 2.2 O=C(OCc1cc([N+](=O)[O-])cc2c1OCOC2)c1ccccn1 nan
16021074 48260 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 1 4 4.3 Cc1cc(C)cc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
CHEMBL1553439 48260 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 1 4 4.3 Cc1cc(C)cc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
16034749 48261 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 2 1 4 4.7 CC1Cn2cc(C(=O)Nc3ccccc3C(F)(F)F)c(=O)c3c(Cl)ccc(c32)O1 nan
CHEMBL1553466 48261 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 2 1 4 4.7 CC1Cn2cc(C(=O)Nc3ccccc3C(F)(F)F)c(=O)c3c(Cl)ccc(c32)O1 nan
16019427 48284 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 9 5.0 COc1ccccc1Nc1nc2c(S(=O)(=O)c3ccc(C(C)C)cc3)nnn2c2ccsc12 nan
CHEMBL1553892 48284 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 9 5.0 COc1ccccc1Nc1nc2c(S(=O)(=O)c3ccc(C(C)C)cc3)nnn2c2ccsc12 nan
16024639 49756 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 1 5 4.1 CCc1ccc(C(=O)c2cn(CC(=O)NCc3ccc(C)cc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1567298 49756 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 1 5 4.1 CCc1ccc(C(=O)c2cn(CC(=O)NCc3ccc(C)cc3)c3nc(C)ccc3c2=O)cc1 nan
16017791 50520 4 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 0 5 2.6 Cc1cc(C)cc(-n2ccn(CC(=O)c3ccc(F)cc3)c(=O)c2=O)c1 nan
CHEMBL1574186 50520 4 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 0 5 2.6 Cc1cc(C)cc(-n2ccn(CC(=O)c3ccc(F)cc3)c(=O)c2=O)c1 nan
935556 51249 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 6 1 5 3.7 O=C(O)c1cccc(CSc2nnc(Cc3ccccc3)o2)c1 nan
CHEMBL1580776 51249 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 6 1 5 3.7 O=C(O)c1cccc(CSc2nnc(Cc3ccccc3)o2)c1 nan
3441236 52592 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 6 3.2 O=c1c2ccccc2nc2sc(Nc3ccc(F)cc3)nn12 nan
CHEMBL1593132 52592 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 6 3.2 O=c1c2ccccc2nc2sc(Nc3ccc(F)cc3)nn12 nan
7199916 52778 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 8 3.5 Cc1cc(NC(=O)CSc2ncnc3c2cnn3-c2cccc(Cl)c2)no1 nan
CHEMBL1595048 52778 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 8 3.5 Cc1cc(NC(=O)CSc2ncnc3c2cnn3-c2cccc(Cl)c2)no1 nan
865684 54136 12 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 4 4.2 COc1ccccc1Nc1nc2cc(C)ccc2cc1C#N nan
CHEMBL1607092 54136 12 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 4 4.2 COc1ccccc1Nc1nc2cc(C)ccc2cc1C#N nan
135421676 109037 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 2.8 Cc1ccccc1CC1SC(N/N=C/c2ccco2)=NC1=O nan
135599408 109037 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 2.8 Cc1ccccc1CC1SC(N/N=C/c2ccco2)=NC1=O nan
137179849 109037 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 2.8 Cc1ccccc1CC1SC(N/N=C/c2ccco2)=NC1=O nan
CHEMBL3212907 109037 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 2.8 Cc1ccccc1CC1SC(N/N=C/c2ccco2)=NC1=O nan
23874512 55366 1 None - 1 Human 6.2 pPotency = 6.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.9 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2OP(=O)(O)OC[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL1397465 55366 1 None - 1 Human 6.2 pPotency = 6.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.9 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2OP(=O)(O)OC[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL1619312 55366 1 None - 1 Human 6.2 pPotency = 6.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.9 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2OP(=O)(O)OC[C@H]2[C@H]1OC(=O)CCC nan
16019610 10832 10 None -50 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 4 1 8 5.0 O=S(=O)(c1cccc(Cl)c1)c1nnn2c1nc(NC1CCCCCC1)c1sccc12 nan
CHEMBL1172404 10832 10 None -50 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 4 1 8 5.0 O=S(=O)(c1cccc(Cl)c1)c1nnn2c1nc(NC1CCCCCC1)c1sccc12 nan
20923126 23085 2 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1C nan
CHEMBL1330832 23085 2 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1C nan
1425004 23239 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 216 3 3 8 -0.5 COC(=O)CNc1nnc(S)nc1O nan
CHEMBL1331930 23239 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 216 3 3 8 -0.5 COC(=O)CNc1nnc(S)nc1O nan
16024792 25055 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 0 5 4.0 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5)CC4)ccc3c2)CC1 nan
CHEMBL1347118 25055 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 0 5 4.0 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5)CC4)ccc3c2)CC1 nan
15989825 26056 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 6 2.9 Cc1ccc(CNc2nc3ccc(C)cc3n3nnnc23)cc1 nan
CHEMBL1355740 26056 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 6 2.9 Cc1ccc(CNc2nc3ccc(C)cc3n3nnnc23)cc1 nan
930238 26735 10 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 1 1 5 4.1 CC(C)c1nc2sc3c(S)ncnc3c2c2c1CCC2 nan
CHEMBL1362595 26735 10 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 1 1 5 4.1 CC(C)c1nc2sc3c(S)ncnc3c2c2c1CCC2 nan
15988284 27649 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccccc3)nnc12 nan
CHEMBL1370040 27649 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccccc3)nnc12 nan
7245805 30814 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 1.8 Cc1ccc(CNC(=O)Cn2ccn(-c3ccc(F)cc3)c(=O)c2=O)cc1 nan
CHEMBL1396990 30814 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 1.8 Cc1ccc(CNC(=O)Cn2ccn(-c3ccc(F)cc3)c(=O)c2=O)cc1 nan
16025341 30917 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 8 1 6 5.0 O=C(CSc1ncc2c(n1)-c1cc(Cl)ccc1N(Cc1ccccc1)S2(=O)=O)NCCc1ccccc1 nan
CHEMBL1398424 30917 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 8 1 6 5.0 O=C(CSc1ncc2c(n1)-c1cc(Cl)ccc1N(Cc1ccccc1)S2(=O)=O)NCCc1ccccc1 nan
995260 31037 13 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 1 3 5.3 CCc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2C)s1 nan
CHEMBL1399507 31037 13 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 1 3 5.3 CCc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2C)s1 nan
3243282 34625 3 None 2 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 1 4 4.3 CCCCn1c(=S)[nH]c2c(oc3ccc(Cl)cc32)c1=O nan
CHEMBL1429998 34625 3 None 2 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 1 4 4.3 CCCCn1c(=S)[nH]c2c(oc3ccc(Cl)cc32)c1=O nan
1007107 35738 14 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 3 1 4 5.8 Cc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
CHEMBL1441054 35738 14 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 3 1 4 5.8 Cc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
16800714 38937 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 7 1 9 0.4 CCCc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1468004 38937 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 7 1 9 0.4 CCCc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
814519 39402 28 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 201 0 2 3 2.4 Sc1[nH]cnc2c3ccccc3nc1-2 nan
CHEMBL1471924 39402 28 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 201 0 2 3 2.4 Sc1[nH]cnc2c3ccccc3nc1-2 nan
44142305 39617 0 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 5 3.1 Cn1cncc1C#Cc1ccc2cc(C3(O)CCCCC3)oc(=O)c2c1 nan
CHEMBL1474528 39617 0 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 5 3.1 Cn1cncc1C#Cc1ccc2cc(C3(O)CCCCC3)oc(=O)c2c1 nan
2138538 48853 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.9 COc1ccc(CCNc2nc3c(-c4cccc(C)c4)nnn3c3ccccc23)cc1OC nan
CHEMBL1559550 48853 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.9 COc1ccc(CCNc2nc3c(-c4cccc(C)c4)nnn3c3ccccc23)cc1OC nan
16028162 49386 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3ccc(F)cc3)cc21 nan
CHEMBL1564507 49386 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3ccc(F)cc3)cc21 nan
7720817 51333 0 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 0 1 5 2.9 Sc1nncn2c1cc1oc3ccccc3c12 nan
CHEMBL1581464 51333 0 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 0 1 5 2.9 Sc1nncn2c1cc1oc3ccccc3c12 nan
1909591 52069 10 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 5 3.4 Oc1c2nc3ccc(Br)cc3c-2ncn1Cc1ccncc1 nan
CHEMBL1587545 52069 10 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 5 3.4 Oc1c2nc3ccc(Br)cc3c-2ncn1Cc1ccncc1 nan
15988964 52483 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCCN(C)CCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1591653 52483 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCCN(C)CCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
44143234 52631 0 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 16 3 12 2.5 CCCC[N+](CCCC)(CCCC)CCCC.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)[O-])[C@@H](O)[C@H]1O nan
CHEMBL1593759 52631 0 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 16 3 12 2.5 CCCC[N+](CCCC)(CCCC)CCCC.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)[O-])[C@@H](O)[C@H]1O nan
660350 55414 6 None -70 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 2 0 3 2.6 O=C(OC1CN2CCC1CC2)c1cccc(Cl)c1 nan
CHEMBL1413816 55414 6 None -70 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 2 0 3 2.6 O=C(OC1CN2CCC1CC2)c1cccc(Cl)c1 nan
CHEMBL1619747 55414 6 None -70 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 2 0 3 2.6 O=C(OC1CN2CCC1CC2)c1cccc(Cl)c1 nan
24892704 71767 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 0 8 2.4 COCCn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2cc(C(=O)OC)ccc21 nan
CHEMBL1967784 71767 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 0 8 2.4 COCCn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2cc(C(=O)OC)ccc21 nan
2815701 105422 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 4 2.6 Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(N(C)C)cc2)cc1 nan
CHEMBL312032 105422 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 4 2.6 Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(N(C)C)cc2)cc1 nan
664514 46442 11 None 3 2 Human 6.1 pPotency = 6.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 6 0 7 3.0 CCOC(=O)CC(=O)CSc1ncnc2c1oc1ccccc12 nan
CHEMBL1537230 46442 11 None 3 2 Human 6.1 pPotency = 6.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 6 0 7 3.0 CCOC(=O)CC(=O)CSc1ncnc2c1oc1ccccc12 nan
4679126 22633 14 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 9 4.3 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(=O)OC)s2)cc1 nan
CHEMBL1327057 22633 14 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 9 4.3 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(=O)OC)s2)cc1 nan
16030531 24084 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 8 1 4 4.9 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1 nan
CHEMBL1338691 24084 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 8 1 4 4.9 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1 nan
1371049 24363 11 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 3.6 COc1ccc(Cl)cc1C(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 nan
CHEMBL1341278 24363 11 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 3.6 COc1ccc(Cl)cc1C(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 nan
3236027 25080 10 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 7 3.9 COc1ccc(N2CCN(c3ccc(NC(=O)c4ccc5c(c4)OCO5)cc3C#N)CC2)cc1 nan
CHEMBL1347313 25080 10 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 7 3.9 COc1ccc(N2CCN(c3ccc(NC(=O)c4ccc5c(c4)OCO5)cc3C#N)CC2)cc1 nan
1208330 25291 16 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 6 0 5 4.6 CCN(CC)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
CHEMBL1349151 25291 16 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 6 0 5 4.6 CCN(CC)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
3414203 26175 13 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 0 5 2.9 Cn1/c(=N\C(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)sc2cc(F)ccc21 nan
CHEMBL1357194 26175 13 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 0 5 2.9 Cn1/c(=N\C(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)sc2cc(F)ccc21 nan
1920995 26839 8 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 2 3 4.1 Cc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
CHEMBL1363550 26839 8 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 2 3 4.1 Cc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
15988900 28191 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 7 5.1 CCOC(=O)c1c(NC(=O)c2cc(-c3ccc(Br)cc3)on2)sc(C(C)=O)c1C nan
CHEMBL1373810 28191 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 7 5.1 CCOC(=O)c1c(NC(=O)c2cc(-c3ccc(Br)cc3)on2)sc(C(C)=O)c1C nan
1450216 30057 5 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 4.2 Cc1ccc(C)c2nc(SCC(=O)NCc3cccs3)c(C#N)cc12 nan
CHEMBL1389491 30057 5 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 4.2 Cc1ccc(C)c2nc(SCC(=O)NCc3cccs3)c(C#N)cc12 nan
3330912 30728 13 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 5 5.9 CCOc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1395727 30728 13 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 5 5.9 CCOc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
16033852 31079 0 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 6 4.1 O=c1c2ccccc2nc2sc(Nc3cccc(C(F)(F)F)c3)nn12 nan
CHEMBL1399988 31079 0 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 6 4.1 O=c1c2ccccc2nc2sc(Nc3cccc(C(F)(F)F)c3)nn12 nan
20923127 31101 5 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 6 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCC(C)C1 nan
CHEMBL1400119 31101 5 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 6 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCC(C)C1 nan
692203 31583 16 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 5 4.5 O=C(Oc1ccccc1)Oc1ccc2c(c1)oc(=O)c1ccccc12 nan
CHEMBL1404472 31583 16 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 5 4.5 O=C(Oc1ccccc1)Oc1ccc2c(c1)oc(=O)c1ccccc12 nan
16745677 32014 0 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 581 9 0 9 6.0 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1Cc1ccc2c(c1)OCO2 nan
CHEMBL1408237 32014 0 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 581 9 0 9 6.0 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1Cc1ccc2c(c1)OCO2 nan
16010801 35078 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 3.1 COc1ccc(CCn2c(=O)c3cccnc3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1OC nan
CHEMBL1433929 35078 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 3.1 COc1ccc(CCn2c(=O)c3cccnc3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1OC nan
4107570 39765 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 1 4 4.8 COc1ccc2c(c1)-c1nc(NC(=O)c3ccc(Cl)cc3)sc1CC2 nan
CHEMBL1476611 39765 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 1 4 4.8 COc1ccc2c(c1)-c1nc(NC(=O)c3ccc(Cl)cc3)sc1CC2 nan
16009524 39791 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 7 4.3 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4c(C)csc4n3)cc2)cc1C nan
CHEMBL1476936 39791 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 7 4.3 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4c(C)csc4n3)cc2)cc1C nan
7184626 40600 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 3.0 CCOc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1484029 40600 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 3.0 CCOc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
4423184 44143 11 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 8 2.6 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(C(=O)OC)ccc21 nan
CHEMBL1516075 44143 11 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 8 2.6 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(C(=O)OC)ccc21 nan
2946893 44487 12 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 9 1 7 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 nan
CHEMBL1519514 44487 12 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 9 1 7 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 nan
2808378 10355 28 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 4 2 4 2.9 CC(=O)c1sccc1NC(=O)c1ccccc1C(=O)O nan
CHEMBL1162443 10355 28 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 4 2 4 2.9 CC(=O)c1sccc1NC(=O)c1ccccc1C(=O)O nan
2085722 22418 3 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 7 1.6 CCCNC(=O)COC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1324965 22418 3 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 7 1.6 CCCNC(=O)COC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
2918454 24023 15 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 8 4.1 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(F)cc2)nc1C nan
CHEMBL1338266 24023 15 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 8 4.1 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(F)cc2)nc1C nan
4902571 24210 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 8 4.3 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(C)cc2)s1 nan
CHEMBL1339921 24210 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 8 4.3 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(C)cc2)s1 nan
15990443 26133 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 5 5.8 COc1cc(Cl)c(C)cc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1356755 26133 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 5 5.8 COc1cc(Cl)c(C)cc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
3442498 27150 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 1 8 1.9 Cc1nnc(NC(=O)CSc2ccc([N+](=O)[O-])cn2)s1 nan
CHEMBL1366225 27150 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 1 8 1.9 Cc1nnc(NC(=O)CSc2ccc([N+](=O)[O-])cn2)s1 nan
18561048 28405 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 8 2.9 CC(=O)Nc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1375333 28405 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 8 2.9 CC(=O)Nc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
5098091 29697 3 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 4 5.6 COc1ccc(-c2sc(C(=O)c3ccc(Cl)cc3Cl)cc2CC(=O)O)cc1 nan
CHEMBL1386663 29697 3 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 4 5.6 COc1ccc(-c2sc(C(=O)c3ccc(Cl)cc3Cl)cc2CC(=O)O)cc1 nan
1112430 36409 20 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 6 3.3 CCOC(=O)c1cccc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 nan
CHEMBL1447146 36409 20 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 6 3.3 CCOC(=O)c1cccc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 nan
734580 37012 15 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 3 1 4 2.2 CC(=O)c1sc(NC(=O)C(C)C)nc1C nan
CHEMBL1451957 37012 15 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 3 1 4 2.2 CC(=O)c1sc(NC(=O)C(C)C)nc1C nan
18561036 37795 9 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 8 2.9 CC(=O)Nc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
CHEMBL1458644 37795 9 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 8 2.9 CC(=O)Nc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
16195440 38480 1 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 4.7 CCn1c(=O)c2cc(C(=O)Nc3cccc(C(C)=O)c3)sc2c2ccccc21 nan
CHEMBL1464378 38480 1 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 4.7 CCn1c(=O)c2cc(C(=O)Nc3cccc(C(C)=O)c3)sc2c2ccccc21 nan
16008699 39580 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 9 2.5 CCOc1ccc(-c2nc(C(N)=O)c3c(n2)n(-c2ccc4c(c2)OCO4)c(=O)n3CC)cc1 nan
CHEMBL1474027 39580 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 9 2.5 CCOc1ccc(-c2nc(C(N)=O)c3c(n2)n(-c2ccc4c(c2)OCO4)c(=O)n3CC)cc1 nan
2746740 41772 5 None 2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 2 6 5.5 O=C(Nc1ccc(Cl)cc1)Nc1ccccc1Sc1ncc([N+](=O)[O-])s1 nan
CHEMBL1493199 41772 5 None 2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 2 6 5.5 O=C(Nc1ccc(Cl)cc1)Nc1ccccc1Sc1ncc([N+](=O)[O-])s1 nan
17469833 42882 9 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 6 3.0 COc1ccccc1NC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
CHEMBL1503328 42882 9 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 6 3.0 COc1ccccc1NC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
17581208 43060 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1ccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)cc1 nan
CHEMBL1505004 43060 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1ccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)cc1 nan
3207506 43317 4 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1ccc2nc(SCC(=O)NCc3cccs3)c(C#N)cc2c1 nan
CHEMBL1507076 43317 4 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1ccc2nc(SCC(=O)NCc3cccs3)c(C#N)cc2c1 nan
16018870 44573 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 4 0 7 6.2 Cc1oc(-c2ccc(Cl)cc2)nc1CSc1nnc(C)n2c1cc1sccc12 nan
CHEMBL1520274 44573 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 4 0 7 6.2 Cc1oc(-c2ccc(Cl)cc2)nc1CSc1nnc(C)n2c1cc1sccc12 nan
1130973 46859 6 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 5 5.1 Cc1ccccc1OCC(=O)Nc1sc(C(=O)Nc2cccc(C)c2C)c(C)c1C#N nan
CHEMBL1540811 46859 6 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 5 5.1 Cc1ccccc1OCC(=O)Nc1sc(C(=O)Nc2cccc(C)c2C)c(C)c1C#N nan
724891 47285 31 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 5 3.5 O=C(O)CSc1ncnc2scc(-c3ccccc3)c12 nan
CHEMBL1544233 47285 31 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 5 3.5 O=C(O)CSc1ncnc2scc(-c3ccccc3)c12 nan
1004390 47806 12 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 8 1 5 4.1 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCCc3ccccc3)n2)c1 nan
CHEMBL1548754 47806 12 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 8 1 5 4.1 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCCc3ccccc3)n2)c1 nan
1450522 48748 5 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 6 3.2 COc1ccc2cc(C#N)c(SCC(=O)N3CC(=O)Nc4ccccc43)nc2c1 nan
CHEMBL1558667 48748 5 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 6 3.2 COc1ccc2cc(C#N)c(SCC(=O)N3CC(=O)Nc4ccccc43)nc2c1 nan
16021094 49090 5 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 4 4.3 CCc1cccc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
CHEMBL1561841 49090 5 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 4 4.3 CCc1cccc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
4585955 50531 7 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 560 6 1 9 4.4 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)CC1 nan
CHEMBL1574238 50531 7 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 560 6 1 9 4.4 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)CC1 nan
16025788 52352 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 4 5.7 CCc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4c(C)cc5ccccc54)s3)CC2)cc1 nan
CHEMBL1590035 52352 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 4 5.7 CCc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4c(C)cc5ccccc54)s3)CC2)cc1 nan
7184644 52456 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 7 2 8 0.2 CC(=O)NCCNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1591356 52456 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 7 2 8 0.2 CC(=O)NCCNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
16010575 52526 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 6 3.2 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)c(C)c1 nan
CHEMBL1592228 52526 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 6 3.2 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)c(C)c1 nan
101430 96404 19 None -1949 5 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 4 9 0.2 OC[C@H]1O[C@@H](n2cnc3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O nan
CHEMBL262083 96404 19 None -1949 5 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 4 9 0.2 OC[C@H]1O[C@@H](n2cnc3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O nan
13273 547 0 None 31 3 Human 7.8 pEC50 = 7.8 Functional
Determined in a cAMP assayDetermined in a cAMP assay
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
163395232 547 0 None 31 3 Human 7.8 pEC50 = 7.8 Functional
Determined in a cAMP assayDetermined in a cAMP assay
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
12501 3429 0 None - 1 Human 9.7 pEC50 = 9.7 Functional
Determined in a cell-based cAMP assay.Determined in a cell-based cAMP assay.
Guide to Pharmacology None None None None 33555858
12501 3429 0 None - 1 Human 9.7 pEC50 = 9.7 Functional
Determined in a cell-based cAMP assay.Determined in a cell-based cAMP assay.
Guide to Pharmacology None None None None 36443381
1989 3277 0 None 17 3 Human 10.4 pEC50 = 10.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 18434306
13273 547 0 None -309 3 Rat 5.3 pEC50 = 5.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
163395232 547 0 None -309 3 Rat 5.3 pEC50 = 5.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
13273 547 0 None -31 3 Mouse 6.3 pEC50 = 6.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
163395232 547 0 None -31 3 Mouse 6.3 pEC50 = 6.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
56593349 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23764525
56593349 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23905199
56593349 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 28592882
8322 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23764525
8322 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23905199
8322 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 28592882
CHEMBL3716980 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23764525
CHEMBL3716980 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23905199
CHEMBL3716980 2554 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 28592882
11898 1112 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 33555858
8346 202 0 None 165 2 Human 8.2 pEC50 = 8.2 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21878627
11462 3721 0 None - 1 Human 9.1 pEC50 = 9.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 30594862
134813895 203 0 None - 1 Human 9.8 pEC50 = 9.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23024363
8349 203 0 None - 1 Human 9.8 pEC50 = 9.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23024363
1988 3281 0 None - 1 Human 8.8 pEC50 None 8.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 16411781
4371 712 0 None - 1 Human 6.2 pIC50 = 6.2 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20043231
4371 712 0 None - 1 Human 6.2 pIC50 = 6.2 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 24812057




Ligands Receptor Assay information Chemical information
Sel. page Common
name
GPCRdb ID #Vendors Reference
ligand
Fold selectivity
(Affinity)
# tested GPCRs
(Affinity)
Species p-value
(-log)
Type Activity
Relation
Activity
Value
Assay Type Assay Description Source Mol
weight
Rot
Bonds
H don H acc LogP Smiles DOI
162654489 180611 0 None - 1 Rat 9.3 pEC50 = 9.3 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180611 0 None - 1 Rat 9.3 pEC50 = 9.3 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162672610 182992 0 None - 0 Rat 9.1 pEC50 = 9.1 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4793799 182992 0 None - 0 Rat 9.1 pEC50 = 9.1 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162664297 182057 0 None - 0 Rat 8.3 pEC50 = 8.3 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781560 182057 0 None - 0 Rat 8.3 pEC50 = 8.3 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162654489 180611 0 None - 1 Human 9.0 pKi = 9.0 Binding
Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayDisplacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180611 0 None - 1 Human 9.0 pKi = 9.0 Binding
Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayDisplacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162662592 181945 0 None - 1 Human 5.5 pKi = 5.5 Binding
Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayDisplacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4780098 181945 0 None - 1 Human 5.5 pKi = 5.5 Binding
Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayDisplacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
12502 2403 0 None 24 2 Human 10.1 pKd = 10.1 Binding
Binding affinity determined by SPR.Binding affinity determined by SPR.
Guide to Pharmacology None None None None 36780899
12502 2403 0 None -24 2 Mouse 8.7 pKd = 8.7 Binding
Binding affinity determined by SPR.Binding affinity determined by SPR.
Guide to Pharmacology None None None None 36780899
8346 202 0 None 9 2 Human 7.0 pKd = 7.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21878627
3874 1590 0 None - 1 Human 9.0 pKd = 9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19343240
3874 1590 0 None - 1 Human 9.3 pKd = 9.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 22425984
1993 3278 0 None - 1 Human 7.3 pKd None 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866
1992 3279 0 None 15 2 Human 9.1 pKd None 9.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866
1994 3280 0 None 39 2 Human 9.4 pKd None 9.4 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866
9321 562 0 None - 1 Human 5.5 pKi = 5.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 30155023
9321 562 0 None - 1 Human 5.5 pKi = 5.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 32295457
4371 712 0 None - 1 Human 5.7 pKi = 5.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20043231
4371 712 0 None - 1 Human 5.7 pKi = 5.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 24812057
1995 2031 0 None -16982 2 Human 5.7 pKi = 5.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23303914
134813895 203 0 None - 1 Human 9.2 pKi = 9.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23024363
8349 203 0 None - 1 Human 9.2 pKi = 9.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23024363
1989 3277 0 None -1 3 Human 9.7 pKi = 9.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 12506116
1989 3277 0 None -1 3 Human 9.7 pKi = 9.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866
1989 3277 0 None -1 3 Human 9.7 pKi = 9.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 18434306
1990 3282 0 None -14 4 Human 7.8 pKi None 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 12506116
1990 3282 0 None -14 4 Human 7.8 pKi None 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866