Ligand source activities (1 row/activity)



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Ligands (move mouse cursor over ligand name to see structure) Receptor Activity Chemical information
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 Activity
Type		 Activity
Relation		 Activity
Value		 p-value
(-log)		 Fold
selectivity		 Tested
GPCRs		 Assay
Description		 Source

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 DOI
90012275 133720 None 0 Human Functional pAC50 = 6.0 6.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 416 6 2 3 5.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(C)(C)C)c1 nan
CHEMBL3714858 133720 None 0 Human Functional pAC50 = 6.0 6.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 416 6 2 3 5.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(C)(C)C)c1 nan
56593334 134190 None 0 Human Functional pAC50 = 6.0 6.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716462 134190 None 0 Human Functional pAC50 = 6.0 6.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90011833 134370 None 0 Human Functional pAC50 = 6.0 6.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc([N+](=O)[O-])c1 nan
CHEMBL3717071 134370 None 0 Human Functional pAC50 = 6.0 6.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc([N+](=O)[O-])c1 nan
56593330 134455 None 0 Human Functional pAC50 = 6.9 6.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717389 134455 None 0 Human Functional pAC50 = 6.9 6.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593346 134400 None 0 Human Functional pAC50 = 5.9 5.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F nan
CHEMBL3717178 134400 None 0 Human Functional pAC50 = 5.9 5.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F nan
90010727 133883 None 0 Human Functional pAC50 = 4.9 4.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 487 6 2 4 4.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cncc(I)c1 nan
CHEMBL3715451 133883 None 0 Human Functional pAC50 = 4.9 4.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 487 6 2 4 4.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cncc(I)c1 nan
118037864 133951 None 0 Human Functional pAC50 = 4.9 4.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 3 3 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2nc[nH]c12 nan
CHEMBL3715676 133951 None 0 Human Functional pAC50 = 4.9 4.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 3 3 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2nc[nH]c12 nan
2806493 134187 None 1 Human Functional pAC50 = 5.9 5.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 nan
CHEMBL3716450 134187 None 1 Human Functional pAC50 = 5.9 5.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 nan
118037922 134755 None 0 Human Functional pAC50 = 5.9 5.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 612 8 2 6 6.1 CC(C)(C)OC(=O)N1CCN(CCOc2ccccc2C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
CHEMBL3718384 134755 None 0 Human Functional pAC50 = 5.9 5.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 612 8 2 6 6.1 CC(C)(C)OC(=O)N1CCN(CCOc2ccccc2C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
90010869 134934 None 0 Human Functional pAC50 = 5.9 5.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 392 6 2 4 4.9 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC)c1 nan
CHEMBL3718995 134934 None 0 Human Functional pAC50 = 5.9 5.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 392 6 2 4 4.9 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC)c1 nan
38269206 134749 None 0 Human Functional pAC50 = 4.9 4.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718363 134749 None 0 Human Functional pAC50 = 4.9 4.9 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90010751 134441 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C\c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
CHEMBL3717338 134441 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C\c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
90012348 134655 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc([N+](=O)[O-])cc1 nan
CHEMBL3718077 134655 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc([N+](=O)[O-])cc1 nan
90010773 133980 None 0 Human Functional pAC50 = 4.8 4.8 -1 2
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 375 4 2 4 4.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccno1 nan
CHEMBL3715750 133980 None 0 Human Functional pAC50 = 4.8 4.8 -1 2
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 375 4 2 4 4.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccno1 nan
90011033 134942 None 0 Human Functional pAC50 = 4.8 4.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2ccccc2c1 nan
CHEMBL3719015 134942 None 0 Human Functional pAC50 = 4.8 4.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2ccccc2c1 nan
56593309 133831 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715203 133831 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90011788 133895 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3715489 133895 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
90012098 134649 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Br)c1 nan
CHEMBL3718061 134649 None 0 Human Functional pAC50 = 5.8 5.8 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Br)c1 nan
56593314 134409 None 0 Human Functional pAC50 = 6.7 6.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717211 134409 None 0 Human Functional pAC50 = 6.7 6.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593340 134169 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3716394 134169 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1313624 134517 None 5 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Cl)c1 nan
CHEMBL3717590 134517 None 5 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Cl)c1 nan
56593311 134556 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717723 134556 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
24671974 134861 None 1 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 3 5.3 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccs1 nan
CHEMBL3718728 134861 None 1 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 3 5.3 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccs1 nan
90012130 133754 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3714976 133754 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
90010778 134282 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C/c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
CHEMBL3716808 134282 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C/c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
56593317 135017 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 nan
CHEMBL3719257 135017 None 0 Human Functional pAC50 = 5.7 5.7 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 nan
40622265 133949 None 1 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 374 4 2 3 4.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccco1 nan
CHEMBL3715664 133949 None 1 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 374 4 2 3 4.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccco1 nan
127024729 134545 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 500 7 2 6 4.0 CCOc1ccccc1C(=O)NC1SC=CC1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717683 134545 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 500 7 2 6 4.0 CCOc1ccccc1C(=O)NC1SC=CC1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010630 134866 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.7 CC1CCC(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
CHEMBL3718740 134866 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.7 CC1CCC(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
5298634 135027 None 7 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 nan
CHEMBL3719295 135027 None 7 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 nan
56593335 134374 None 0 Human Functional pAC50 = 6.6 6.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717089 134374 None 0 Human Functional pAC50 = 6.6 6.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011775 133741 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)cc1 nan
CHEMBL3714926 133741 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)cc1 nan
90011735 133839 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 511 8 2 4 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCCCC1 nan
CHEMBL3715244 133839 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 511 8 2 4 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCCCC1 nan
56593308 134228 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716596 134228 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593324 134285 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 8 2 5 5.2 CCOc1ccccc1C(=O)Nc1ccccc1CNc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3716811 134285 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 8 2 5 5.2 CCOc1ccccc1C(=O)Nc1ccccc1CNc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593333 134304 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716871 134304 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593350 134716 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3718273 134716 None 0 Human Functional pAC50 = 5.6 5.6 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
56593315 134381 None 0 Human Functional pAC50 = 6.5 6.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3717103 134381 None 0 Human Functional pAC50 = 6.5 6.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
90010752 133764 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 448 4 2 2 5.1 O=C(Nc1cccc(I)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3714999 133764 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 448 4 2 2 5.1 O=C(Nc1cccc(I)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90011874 133781 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1 nan
CHEMBL3715040 133781 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1 nan
56593323 133805 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715105 133805 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593318 134201 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 nan
CHEMBL3716512 134201 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 nan
90010791 134341 None 0 Human Functional pAC50 = 4.5 4.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccccn1 nan
CHEMBL3716987 134341 None 0 Human Functional pAC50 = 4.5 4.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccccn1 nan
56593313 134920 None 0 Human Functional pAC50 = 4.5 4.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 nan
CHEMBL3718895 134920 None 0 Human Functional pAC50 = 4.5 4.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 nan
56593329 134502 None 0 Human Functional pAC50 = 6.5 6.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717553 134502 None 0 Human Functional pAC50 = 6.5 6.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593336 133912 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715551 133912 None 0 Human Functional pAC50 = 5.5 5.5 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593337 133801 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl nan
CHEMBL3715097 133801 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl nan
127024591 133812 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 457 8 3 4 4.8 CNCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715139 133812 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 457 8 3 4 4.8 CNCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
2233108 134538 None 6 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3717655 134538 None 6 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1511185 133906 None 8 Human Functional pAC50 = 4.4 4.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3715535 133906 None 8 Human Functional pAC50 = 4.4 4.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
4795548 134306 None 2 Human Functional pAC50 = 4.4 4.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3716878 134306 None 2 Human Functional pAC50 = 4.4 4.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
32157880 134312 None 2 Human Functional pAC50 = 4.4 4.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1ccc(F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716901 134312 None 2 Human Functional pAC50 = 4.4 4.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1ccc(F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
90010785 133756 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 574 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1I nan
CHEMBL3714984 133756 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 574 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1I nan
118043134 133804 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 4 2 2 7.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
CHEMBL3715104 133804 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 4 2 2 7.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
21179517 134018 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 2 2 6.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715901 134018 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 2 2 6.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1cccc(C(F)(F)F)c1 nan
56593306 134363 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717045 134363 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90012794 134581 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Br)cc1 nan
CHEMBL3717803 134581 None 0 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Br)cc1 nan
54784887 134751 None 1 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1ccccc1 nan
CHEMBL3718373 134751 None 1 Human Functional pAC50 = 5.4 5.4 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1ccccc1 nan
1313916 40109 None 5 Human Functional pAC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1479446 40109 None 5 Human Functional pAC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593322 133794 None 0 Human Functional pAC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715081 133794 None 0 Human Functional pAC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593331 134795 None 0 Human Functional pAC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718541 134795 None 0 Human Functional pAC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011206 133878 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 513 8 2 5 4.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCOCC1 nan
CHEMBL3715429 133878 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 513 8 2 5 4.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCOCC1 nan
56593347 133908 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715539 133908 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010797 133934 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 4 2 2 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C12CC3CC(CC(C3)C1)C2 nan
CHEMBL3715615 133934 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 4 2 2 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C12CC3CC(CC(C3)C1)C2 nan
4484023 134338 None 4 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3716976 134338 None 4 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
56593338 134800 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 8 2 5 3.1 CCOc1ccccc1C(=O)NCCC(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3718557 134800 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 8 2 5 3.1 CCOc1ccccc1C(=O)NCCC(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593307 134890 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 386 5 2 3 5.7 COc1ccccc1Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718811 134890 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 386 5 2 3 5.7 COc1ccccc1Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011315 134274 None 0 Human Functional pAC50 = 4.3 4.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 370 5 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccccc1 nan
CHEMBL3716765 134274 None 0 Human Functional pAC50 = 4.3 4.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 370 5 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccccc1 nan
127024076 134558 None 1 Human Functional pAC50 = 4.3 4.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 308 4 2 2 3.5 O=CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717734 134558 None 1 Human Functional pAC50 = 4.3 4.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 308 4 2 2 3.5 O=CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010896 134598 None 0 Human Functional pAC50 = 4.3 4.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 438 5 2 2 6.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1cccc(C(F)(F)F)c1 nan
CHEMBL3717869 134598 None 0 Human Functional pAC50 = 4.3 4.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 438 5 2 2 6.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1cccc(C(F)(F)F)c1 nan
56593316 133837 None 0 Human Functional pAC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715235 133837 None 0 Human Functional pAC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593341 133904 None 0 Human Functional pAC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 508 7 2 5 5.6 CCSc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715526 133904 None 0 Human Functional pAC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 508 7 2 5 5.6 CCSc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010758 133886 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 5 2 2 6.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccccc2)c1 nan
CHEMBL3715462 133886 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 5 2 2 6.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccccc2)c1 nan
56593299 134082 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3716127 134082 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
56593339 134194 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716488 134194 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593319 134286 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716813 134286 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010729 134292 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 6 2 4 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(N2CCCCC2)c1 nan
CHEMBL3716829 134292 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 6 2 4 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(N2CCCCC2)c1 nan
90010865 134791 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 380 3 2 3 5.3 CC(C)(C)OC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718514 134791 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 380 3 2 3 5.3 CC(C)(C)OC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010599 135031 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 5 2 2 5.6 CC(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3719301 135031 None 0 Human Functional pAC50 = 5.3 5.3 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 5 2 2 5.6 CC(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
90011364 134128 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 5 2 2 6.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCC1CCCCC1 nan
CHEMBL3716260 134128 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 5 2 2 6.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCC1CCCCC1 nan
90011496 134218 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2ccccc12 nan
CHEMBL3716563 134218 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2ccccc12 nan
90011579 134339 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1 nan
CHEMBL3716978 134339 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1 nan
56593303 134686 None 1 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 nan
CHEMBL3718178 134686 None 1 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 nan
60288826 134717 None 1 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 426 5 2 3 5.4 CC(=O)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3718279 134717 None 1 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 426 5 2 3 5.4 CC(=O)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
56593326 134816 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718612 134816 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593302 133845 None 0 Human Functional pAC50 = 4.2 4.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715266 133845 None 0 Human Functional pAC50 = 4.2 4.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011338 133861 None 0 Human Functional pAC50 = 4.2 4.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 485 9 2 4 5.5 CN(C)CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715346 133861 None 0 Human Functional pAC50 = 4.2 4.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 485 9 2 4 5.5 CN(C)CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593298 134551 None 0 Human Functional pAC50 = 4.2 4.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 6 2 3 5.6 COc1ccccc1CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717700 134551 None 0 Human Functional pAC50 = 4.2 4.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 6 2 3 5.6 COc1ccccc1CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010708 134364 None 0 Human Functional pAC50 = 6.2 6.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 6 2 4 4.5 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C#N)c1 nan
CHEMBL3717047 134364 None 0 Human Functional pAC50 = 6.2 6.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 6 2 4 4.5 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C#N)c1 nan
118043136 134994 None 0 Human Functional pAC50 = 6.2 6.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 7 2 4 6.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3719197 134994 None 0 Human Functional pAC50 = 6.2 6.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 7 2 4 6.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
90010848 133803 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 6 2 5 3.6 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(C)(=O)=O)c1 nan
CHEMBL3715101 133803 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 6 2 5 3.6 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(C)(=O)=O)c1 nan
90010777 134646 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 346 4 2 2 4.4 C#Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3718054 134646 None 0 Human Functional pAC50 = 5.2 5.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 346 4 2 2 4.4 C#Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
118037818 134778 None 0 Human Functional pAC50 = 5.2 5.2 -1 2
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 4 2 4 4.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2 nan
CHEMBL3718470 134778 None 0 Human Functional pAC50 = 5.2 5.2 -1 2
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 4 2 4 4.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2 nan
56593305 134759 None 0 Human Functional pAC50 = 7.2 7.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
CHEMBL3718400 134759 None 0 Human Functional pAC50 = 7.2 7.2 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
90010645 133860 None 0 Human Functional pAC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 486 6 2 3 5.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(I)c1 nan
CHEMBL3715345 133860 None 0 Human Functional pAC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 486 6 2 3 5.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(I)c1 nan
56593345 133976 None 0 Human Functional pAC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715743 133976 None 0 Human Functional pAC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593320 134211 None 0 Human Functional pAC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716540 134211 None 0 Human Functional pAC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011367 134843 None 0 Human Functional pAC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 476 6 2 3 7.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1Oc1ccccc1 nan
CHEMBL3718664 134843 None 0 Human Functional pAC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 476 6 2 3 7.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1Oc1ccccc1 nan
56593296 134226 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716581 134226 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011087 134342 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1C(F)(F)F nan
CHEMBL3716990 134342 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1C(F)(F)F nan
90011219 134727 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 510 4 2 2 5.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1I nan
CHEMBL3718291 134727 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 510 4 2 2 5.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1I nan
90011247 134785 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Br nan
CHEMBL3718498 134785 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Br nan
52764307 134937 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccncc1 nan
CHEMBL3719005 134937 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccncc1 nan
90010748 133806 None 0 Human Functional pAC50 = 4.1 4.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1ccc([N+](=O)[O-])cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715107 133806 None 0 Human Functional pAC50 = 4.1 4.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1ccc([N+](=O)[O-])cc1)c1ccccc1NC(=O)C1CCCCC1 nan
90010731 133963 None 0 Human Functional pAC50 = 4.1 4.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccncc1 nan
CHEMBL3715708 133963 None 0 Human Functional pAC50 = 4.1 4.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccncc1 nan
3348337 134518 None 0 Human Functional pAC50 = 4.1 4.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 3 2 2 3.9 CC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717591 134518 None 0 Human Functional pAC50 = 4.1 4.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 3 2 2 3.9 CC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
29448220 134931 None 0 Human Functional pAC50 = 4.1 4.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 366 4 2 4 4.2 O=C(Nc1ccc2c(c1)OCO2)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718975 134931 None 0 Human Functional pAC50 = 4.1 4.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 366 4 2 4 4.2 O=C(Nc1ccc2c(c1)OCO2)c1ccccc1NC(=O)C1CCCCC1 nan
56593344 133766 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715001 133766 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593325 134836 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 nan
CHEMBL3718643 134836 None 0 Human Functional pAC50 = 5.1 5.1 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 nan
56593349 2571 None 25 Human Functional pAC50 = 7.0 7.0 22 3
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
8322 2571 None 25 Human Functional pAC50 = 7.0 7.0 22 3
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
CHEMBL3716980 2571 None 25 Human Functional pAC50 = 7.0 7.0 22 3
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
90011702 133821 None 0 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.9 O=C(Nc1ccc2c(c1)CCC2)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715166 133821 None 0 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.9 O=C(Nc1ccc2c(c1)CCC2)c1ccccc1NC(=O)C1CCCCC1 nan
56593321 134555 None 0 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717718 134555 None 0 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 nan
90011489 134668 None 0 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 6 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCCc1ccccc1 nan
CHEMBL3718114 134668 None 0 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 6 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCCc1ccccc1 nan
60589025 134864 None 1 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 5 2 4 4.6 CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3718735 134864 None 1 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 5 2 4 4.6 CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1320335 134891 None 6 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3718813 134891 None 6 Human Functional pAC50 = 5.0 5.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
730108 41552 None 11 Human Functional pAC50 = 4.0 4.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1491180 41552 None 11 Human Functional pAC50 = 4.0 4.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 nan
56593342 134486 None 0 Human Functional pAC50 = 4.0 4.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717485 134486 None 0 Human Functional pAC50 = 4.0 4.0 - 1
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
162654489 180741 None 0 Human Functional pEC50 = 10.5 10.5 4 2
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180741 None 0 Human Functional pEC50 = 10.5 10.5 4 2
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162648163 179979 None 0 Human Functional pEC50 = 10 10.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4745611 179979 None 0 Human Functional pEC50 = 10 10.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672427 183305 None 0 Human Functional pEC50 = 9.7 9.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4795810 183305 None 0 Human Functional pEC50 = 9.7 9.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162667576 182590 None 0 Human Functional pEC50 = 9.4 9.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4786789 182590 None 0 Human Functional pEC50 = 9.4 9.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162654489 180741 None 0 Human Functional pEC50 = 9.4 9.4 4 2
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180741 None 0 Human Functional pEC50 = 9.4 9.4 4 2
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162677247 183636 None 0 Human Functional pEC50 = 9.2 9.2 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
CHEMBL4799907 183636 None 0 Human Functional pEC50 = 9.2 9.2 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
162661030 181555 None 0 Human Functional pEC50 = 9 9.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4764326 181555 None 0 Human Functional pEC50 = 9 9.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162674882 183458 None 0 Human Functional pEC50 = 9 9.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797641 183458 None 0 Human Functional pEC50 = 9 9.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593316 133837 None 0 Human Functional pEC50 = 7.0 7.0 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715235 133837 None 0 Human Functional pEC50 = 7.0 7.0 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593334 134190 None 0 Human Functional pEC50 = 6.0 6.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716462 134190 None 0 Human Functional pEC50 = 6.0 6.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593305 134759 None 0 Human Functional pEC50 = 7.0 7.0 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
CHEMBL3718400 134759 None 0 Human Functional pEC50 = 7.0 7.0 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
56593346 134400 None 0 Human Functional pEC50 = 5.9 5.9 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F 10.1016/j.ejmech.2018.06.008
CHEMBL3717178 134400 None 0 Human Functional pEC50 = 5.9 5.9 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F 10.1016/j.ejmech.2018.06.008
162664297 182187 None 0 Human Functional pEC50 = 7.9 7.9 -2 2
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781560 182187 None 0 Human Functional pEC50 = 7.9 7.9 -2 2
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593322 133794 None 0 Human Functional pEC50 = 6.9 6.9 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715081 133794 None 0 Human Functional pEC50 = 6.9 6.9 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
162649438 180158 None 0 Human Functional pEC50 = 6.9 6.9 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3412 125 54 48 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4747756 180158 None 0 Human Functional pEC50 = 6.9 6.9 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3412 125 54 48 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
2806493 134187 None 1 Human Functional pEC50 = 5.9 5.9 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 10.1016/j.ejmech.2018.06.008
CHEMBL3716450 134187 None 1 Human Functional pEC50 = 5.9 5.9 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 10.1016/j.ejmech.2018.06.008
38269206 134749 None 0 Human Functional pEC50 = 4.9 4.9 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718363 134749 None 0 Human Functional pEC50 = 4.9 4.9 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
162659815 181306 None 0 Human Functional pEC50 = 7.9 7.9 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2785 100 45 39 -13.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4761130 181306 None 0 Human Functional pEC50 = 7.9 7.9 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2785 100 45 39 -13.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162666079 182419 None 0 Human Functional pEC50 = 7.9 7.9 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2855 106 46 40 -12.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4784237 182419 None 0 Human Functional pEC50 = 7.9 7.9 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2855 106 46 40 -12.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162656358 180995 None 0 Human Functional pEC50 = 6.8 6.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3355 121 53 47 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4757578 180995 None 0 Human Functional pEC50 = 6.8 6.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3355 121 53 47 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162677445 183649 None 0 Human Functional pEC50 = 6.8 6.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3139 113 49 43 -12.2 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4800116 183649 None 0 Human Functional pEC50 = 6.8 6.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3139 113 49 43 -12.2 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593309 133831 None 0 Human Functional pEC50 = 5.8 5.8 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715203 133831 None 0 Human Functional pEC50 = 5.8 5.8 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162646950 179785 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3195 119 50 44 -12.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4743539 179785 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3195 119 50 44 -12.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162643258 181848 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3411 126 53 47 -12.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(C)C(=O)NCC(C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O 10.1021/acs.jmedchem.0c01533
CHEMBL4777259 181848 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3411 126 53 47 -12.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(C)C(=O)NCC(C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O 10.1021/acs.jmedchem.0c01533
162674863 183419 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3509 135 52 47 -9.4 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797258 183419 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3509 135 52 47 -9.4 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162662427 182064 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3383 123 53 47 -14.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4779982 182064 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3383 123 53 47 -14.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162648609 179921 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3292 122 50 45 -12.0 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4744987 179921 None 0 Human Functional pEC50 = 7.8 7.8 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3292 122 50 45 -12.0 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672427 183305 None 0 Human Functional pEC50 = 7.7 7.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4795810 183305 None 0 Human Functional pEC50 = 7.7 7.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593314 134409 None 0 Human Functional pEC50 = 6.7 6.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717211 134409 None 0 Human Functional pEC50 = 6.7 6.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593330 134455 None 0 Human Functional pEC50 = 6.7 6.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717389 134455 None 0 Human Functional pEC50 = 6.7 6.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
1313916 40109 None 5 Human Functional pEC50 = 5.7 5.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL1479446 40109 None 5 Human Functional pEC50 = 5.7 5.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593340 134169 None 0 Human Functional pEC50 = 5.7 5.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716394 134169 None 0 Human Functional pEC50 = 5.7 5.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 10.1016/j.ejmech.2018.06.008
56593311 134556 None 0 Human Functional pEC50 = 5.7 5.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717723 134556 None 0 Human Functional pEC50 = 5.7 5.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
162650672 180262 None 0 Human Functional pEC50 = 7.7 7.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3152 116 49 43 -12.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4748931 180262 None 0 Human Functional pEC50 = 7.7 7.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3152 116 49 43 -12.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162648163 179979 None 0 Human Functional pEC50 = 7.7 7.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4745611 179979 None 0 Human Functional pEC50 = 7.7 7.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593349 2571 None 25 Human Functional pEC50 = 6.7 6.7 22 3
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
8322 2571 None 25 Human Functional pEC50 = 6.7 6.7 22 3
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
CHEMBL3716980 2571 None 25 Human Functional pEC50 = 6.7 6.7 22 3
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
162659417 181332 None 0 Human Functional pEC50 = 6.7 6.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3257 114 52 46 -15.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4761424 181332 None 0 Human Functional pEC50 = 6.7 6.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3257 114 52 46 -15.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162670766 183058 None 0 Human Functional pEC50 = 6.7 6.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3097 111 49 43 -13.1 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4792874 183058 None 0 Human Functional pEC50 = 6.7 6.7 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3097 111 49 43 -13.1 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593317 135017 None 0 Human Functional pEC50 = 5.7 5.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3719257 135017 None 0 Human Functional pEC50 = 5.7 5.7 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 10.1016/j.ejmech.2018.06.008
162654519 180776 None 0 Human Functional pEC50 = 7.6 7.6 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2828 103 46 40 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4755239 180776 None 0 Human Functional pEC50 = 7.6 7.6 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2828 103 46 40 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162654037 180780 None 0 Human Functional pEC50 = 6.6 6.6 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3424 126 53 47 -12.7 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4755289 180780 None 0 Human Functional pEC50 = 6.6 6.6 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3424 126 53 47 -12.7 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
5298634 135027 None 7 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3719295 135027 None 7 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 10.1016/j.ejmech.2018.06.008
56593332 162345 None 0 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 498 7 2 6 4.9 CCOc1ccccc1C(=O)Nc1sccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL4163593 162345 None 0 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 498 7 2 6 4.9 CCOc1ccccc1C(=O)Nc1sccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162667576 182590 None 0 Human Functional pEC50 = 7.6 7.6 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4786789 182590 None 0 Human Functional pEC50 = 7.6 7.6 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593335 134374 None 0 Human Functional pEC50 = 6.6 6.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717089 134374 None 0 Human Functional pEC50 = 6.6 6.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593308 134228 None 0 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716596 134228 None 0 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593333 134304 None 0 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716871 134304 None 0 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593350 134716 None 0 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718273 134716 None 0 Human Functional pEC50 = 5.6 5.6 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
162672610 183122 None 0 Human Functional pEC50 = 6.6 6.6 -35 2
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4793799 183122 None 0 Human Functional pEC50 = 6.6 6.6 -35 2
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593323 133805 None 0 Human Functional pEC50 = 5.5 5.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715105 133805 None 0 Human Functional pEC50 = 5.5 5.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593318 134201 None 0 Human Functional pEC50 = 5.5 5.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716512 134201 None 0 Human Functional pEC50 = 5.5 5.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 10.1016/j.ejmech.2018.06.008
56593313 134920 None 0 Human Functional pEC50 = 4.5 4.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718895 134920 None 0 Human Functional pEC50 = 4.5 4.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162652974 180523 None 0 Human Functional pEC50 = 8.5 8.5 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4163 175 54 60 -9.4 CCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4752287 180523 None 0 Human Functional pEC50 = 8.5 8.5 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4163 175 54 60 -9.4 CCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672610 183122 None 0 Human Functional pEC50 = 8.4 8.4 -35 2
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4793799 183122 None 0 Human Functional pEC50 = 8.4 8.4 -35 2
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162674882 183458 None 0 Human Functional pEC50 = 7.5 7.5 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797641 183458 None 0 Human Functional pEC50 = 7.5 7.5 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162669540 182745 None 0 Human Functional pEC50 = 7.5 7.5 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2867 105 45 40 -11.9 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4788675 182745 None 0 Human Functional pEC50 = 7.5 7.5 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2867 105 45 40 -11.9 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162670803 182942 None 0 Human Functional pEC50 = 7.5 7.5 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3314 119 53 47 -14.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4791290 182942 None 0 Human Functional pEC50 = 7.5 7.5 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3314 119 53 47 -14.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593329 134502 None 0 Human Functional pEC50 = 6.5 6.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717553 134502 None 0 Human Functional pEC50 = 6.5 6.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593336 133912 None 0 Human Functional pEC50 = 5.5 5.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3715551 133912 None 0 Human Functional pEC50 = 5.5 5.5 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593314 134409 None 0 Human Functional pEC50 = 6.5 6.5 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717211 134409 None 0 Human Functional pEC50 = 6.5 6.5 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593330 134455 None 0 Human Functional pEC50 = 6.4 6.4 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717389 134455 None 0 Human Functional pEC50 = 6.4 6.4 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
162648114 180021 None 0 Human Functional pEC50 = 6.4 6.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4489 180 64 59 -8.3 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4746080 180021 None 0 Human Functional pEC50 = 6.4 6.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4489 180 64 59 -8.3 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162649375 180226 None 0 Human Functional pEC50 = 7.4 7.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3327 120 53 47 -15.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4748601 180226 None 0 Human Functional pEC50 = 7.4 7.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3327 120 53 47 -15.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593337 133801 None 0 Human Functional pEC50 = 5.4 5.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl 10.1016/j.ejmech.2018.06.008
CHEMBL3715097 133801 None 0 Human Functional pEC50 = 5.4 5.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl 10.1016/j.ejmech.2018.06.008
56593300 162295 None 0 Human Functional pEC50 = 5.4 5.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 471 8 2 4 5.2 CN(C)CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL4162685 162295 None 0 Human Functional pEC50 = 5.4 5.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 471 8 2 4 5.2 CN(C)CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
1511185 133906 None 8 Human Functional pEC50 = 4.4 4.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715535 133906 None 8 Human Functional pEC50 = 4.4 4.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
4795548 134306 None 2 Human Functional pEC50 = 4.4 4.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716878 134306 None 2 Human Functional pEC50 = 4.4 4.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
162646638 179820 None 0 Human Functional pEC50 = 6.4 6.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3055 109 49 43 -14.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4743958 179820 None 0 Human Functional pEC50 = 6.4 6.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3055 109 49 43 -14.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593306 134363 None 0 Human Functional pEC50 = 5.4 5.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717045 134363 None 0 Human Functional pEC50 = 5.4 5.4 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162644941 179506 None 0 Human Functional pEC50 = 7.4 7.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2883 107 46 40 -11.8 CC[C@H](C)[C@H](NC(=O)C(C)CNC(=O)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4739969 179506 None 0 Human Functional pEC50 = 7.4 7.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2883 107 46 40 -11.8 CC[C@H](C)[C@H](NC(=O)C(C)CNC(=O)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162649856 180245 None 0 Human Functional pEC50 = 7.4 7.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3481 130 54 48 -12.8 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4748830 180245 None 0 Human Functional pEC50 = 7.4 7.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3481 130 54 48 -12.8 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162663002 182154 None 0 Human Functional pEC50 = 7.4 7.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3122 115 48 43 -11.7 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781139 182154 None 0 Human Functional pEC50 = 7.4 7.4 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3122 115 48 43 -11.7 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162655145 180864 None 0 Human Functional pEC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3166 116 49 43 -11.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4756139 180864 None 0 Human Functional pEC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3166 116 49 43 -11.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
56593322 133794 None 0 Human Functional pEC50 = 7.3 7.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715081 133794 None 0 Human Functional pEC50 = 7.3 7.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
47936 193531 None 56 Human Functional pEC50 = 7.3 7.3 25 6
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 410 2 3 7 1.5 C=C[C@@]1(C)CC(=O)[C@@]2(O)[C@](C)(O1)[C@@H](OC(C)=O)[C@@H](O)[C@H]1C(C)(C)CC[C@H](O)[C@@]12C 10.1016/j.ejmech.2018.06.008
CHEMBL52606 193531 None 56 Human Functional pEC50 = 7.3 7.3 25 6
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 410 2 3 7 1.5 C=C[C@@]1(C)CC(=O)[C@@]2(O)[C@](C)(O1)[C@@H](OC(C)=O)[C@@H](O)[C@H]1C(C)(C)CC[C@H](O)[C@@]12C 10.1016/j.ejmech.2018.06.008
56593331 134795 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718541 134795 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593335 134374 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717089 134374 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593347 133908 None 0 Human Functional pEC50 = 5.3 5.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715539 133908 None 0 Human Functional pEC50 = 5.3 5.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162654330 179860 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3299 116 52 46 -14.6 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4744303 179860 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3299 116 52 46 -14.6 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593316 133837 None 0 Human Functional pEC50 = 7.3 7.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715235 133837 None 0 Human Functional pEC50 = 7.3 7.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162654892 180726 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3083 110 49 43 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4754697 180726 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3083 110 49 43 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593315 134381 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3717103 134381 None 0 Human Functional pEC50 = 6.3 6.3 - 1
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
56593299 134082 None 0 Human Functional pEC50 = 5.3 5.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716127 134082 None 0 Human Functional pEC50 = 5.3 5.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
56593339 134194 None 0 Human Functional pEC50 = 5.3 5.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716488 134194 None 0 Human Functional pEC50 = 5.3 5.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593319 134286 None 0 Human Functional pEC50 = 5.3 5.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716813 134286 None 0 Human Functional pEC50 = 5.3 5.3 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162670817 182955 None 0 Human Functional pEC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3209 121 50 44 -11.0 CC[C@H](C)[C@H](NC[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4791486 182955 None 0 Human Functional pEC50 = 7.3 7.3 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3209 121 50 44 -11.0 CC[C@H](C)[C@H](NC[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
56593303 134686 None 1 Human Functional pEC50 = 5.2 5.2 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 10.1016/j.ejmech.2018.06.008
CHEMBL3718178 134686 None 1 Human Functional pEC50 = 5.2 5.2 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 10.1016/j.ejmech.2018.06.008
56593326 134816 None 0 Human Functional pEC50 = 5.2 5.2 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718612 134816 None 0 Human Functional pEC50 = 5.2 5.2 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593302 133845 None 0 Human Functional pEC50 = 4.2 4.2 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715266 133845 None 0 Human Functional pEC50 = 4.2 4.2 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593305 134759 None 0 Human Functional pEC50 = 7.2 7.2 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F 10.1016/j.ejmech.2018.06.008
CHEMBL3718400 134759 None 0 Human Functional pEC50 = 7.2 7.2 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F 10.1016/j.ejmech.2018.06.008
162656612 181023 None 0 Human Functional pEC50 = 6.2 6.2 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3041 106 48 42 -13.3 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4757890 181023 None 0 Human Functional pEC50 = 6.2 6.2 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3041 106 48 42 -13.3 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593345 133976 None 0 Human Functional pEC50 = 6.1 6.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715743 133976 None 0 Human Functional pEC50 = 6.1 6.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593320 134211 None 0 Human Functional pEC50 = 6.1 6.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716540 134211 None 0 Human Functional pEC50 = 6.1 6.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593296 134226 None 0 Human Functional pEC50 = 5.1 5.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716581 134226 None 0 Human Functional pEC50 = 5.1 5.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162662592 182075 None 1 Human Functional pEC50 = 5.1 5.1 - 1
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4780098 182075 None 1 Human Functional pEC50 = 5.1 5.1 - 1
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162675717 183383 None 0 Human Functional pEC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4461 178 64 59 -9.0 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4796713 183383 None 0 Human Functional pEC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4461 178 64 59 -9.0 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593344 133766 None 0 Human Functional pEC50 = 5.1 5.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715001 133766 None 0 Human Functional pEC50 = 5.1 5.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593325 134836 None 0 Human Functional pEC50 = 5.1 5.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718643 134836 None 0 Human Functional pEC50 = 5.1 5.1 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 10.1016/j.ejmech.2018.06.008
162661030 181555 None 0 Human Functional pEC50 = 7.1 7.1 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4764326 181555 None 0 Human Functional pEC50 = 7.1 7.1 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162661521 181636 None 0 Human Functional pEC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3341 120 53 47 -14.6 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4765167 181636 None 0 Human Functional pEC50 = 6.1 6.1 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3341 120 53 47 -14.6 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162677247 183636 None 0 Human Functional pEC50 = 8.1 8.1 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
CHEMBL4799907 183636 None 0 Human Functional pEC50 = 8.1 8.1 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
162666829 182531 None 0 Human Functional pEC50 = 7.0 7.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3069 110 49 43 -13.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4785899 182531 None 0 Human Functional pEC50 = 7.0 7.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3069 110 49 43 -13.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162664515 182181 None 0 Human Functional pEC50 = 6.0 6.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3027 105 48 42 -13.5 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781482 182181 None 0 Human Functional pEC50 = 6.0 6.0 - 1
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3027 105 48 42 -13.5 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593349 2571 None 25 Human Functional pEC50 = 7.0 7.0 22 3
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
8322 2571 None 25 Human Functional pEC50 = 7.0 7.0 22 3
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
CHEMBL3716980 2571 None 25 Human Functional pEC50 = 7.0 7.0 22 3
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
56593321 134555 None 0 Human Functional pEC50 = 5.0 5.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717718 134555 None 0 Human Functional pEC50 = 5.0 5.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
1320335 134891 None 6 Human Functional pEC50 = 5.0 5.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 10.1016/j.ejmech.2018.06.008
CHEMBL3718813 134891 None 6 Human Functional pEC50 = 5.0 5.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 10.1016/j.ejmech.2018.06.008
730108 41552 None 11 Human Functional pEC50 = 4.0 4.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL1491180 41552 None 11 Human Functional pEC50 = 4.0 4.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593342 134486 None 0 Human Functional pEC50 = 4.0 4.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717485 134486 None 0 Human Functional pEC50 = 4.0 4.0 - 1
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
820020 21833 None 3 Human Functional pPotency = 7 7.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 2 2 3 1.6 O=C(NN=C1CCCC1)c1[nH]nc2c1CCC2 nan
CHEMBL1319564 21833 None 3 Human Functional pPotency = 7 7.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 2 2 3 1.6 O=C(NN=C1CCCC1)c1[nH]nc2c1CCC2 nan
2146184 44580 None 8 Human Functional pPotency = 7 7.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 4 2.4 CN(C)c1ccc(C(=S)N2CCN(S(=O)(=O)c3ccccc3)CC2)cc1 nan
CHEMBL1519935 44580 None 8 Human Functional pPotency = 7 7.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 4 2.4 CN(C)c1ccc(C(=S)N2CCN(S(=O)(=O)c3ccccc3)CC2)cc1 nan
1761 99730 None 6 Human Functional pPotency = 6 6.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 4 9 -1.7 Nc1ncnc2c1ncn2C1OC(C(=O)NC2CC2)C(O)C1O nan
CHEMBL28449 99730 None 6 Human Functional pPotency = 6 6.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 4 9 -1.7 Nc1ncnc2c1ncn2C1OC(C(=O)NC2CC2)C(O)C1O nan
16019574 10885 None 10 Human Functional pPotency = 5 5.0 -14 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(F)cc1)c1sccc12 nan
CHEMBL1172596 10885 None 10 Human Functional pPotency = 5 5.0 -14 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(F)cc1)c1sccc12 nan
4132952 19678 None 0 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 11 0.2 CCOP1(=O)OCC2OC(n3cnc4c(N)ncnc43)C(O)C2O1 nan
CHEMBL1300691 19678 None 0 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 11 0.2 CCOP1(=O)OCC2OC(n3cnc4c(N)ncnc43)C(O)C2O1 nan
54677759 21097 None 3 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 3 4.1 O=c1c(Cc2ccccc2)c(O)c2cccc3c4c(n1c23)CCCC4 nan
CHEMBL1312172 21097 None 3 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 3 4.1 O=c1c(Cc2ccccc2)c(O)c2cccc3c4c(n1c23)CCCC4 nan
16027480 21530 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
CHEMBL1316197 21530 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
941768 22098 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 3 7 -0.5 O=C1NC(=O)C(=NNc2ccc3c(c2)COC3=O)C(=O)N1 nan
CHEMBL1321879 22098 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 3 7 -0.5 O=C1NC(=O)C(=NNc2ccc3c(c2)COC3=O)C(=O)N1 nan
2764158 22655 None 20 Human Functional pPotency = 5 5.0 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 2 1 5 2.7 CSc1ccccc1-c1nnc(S)o1 nan
CHEMBL1326901 22655 None 20 Human Functional pPotency = 5 5.0 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 2 1 5 2.7 CSc1ccccc1-c1nnc(S)o1 nan
2810145 25944 None 3 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 3.6 COc1cc2nc(NC(=O)c3ccc(Cl)cc3)sc(=O)c2cc1OC nan
CHEMBL1354031 25944 None 3 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 3.6 COc1cc2nc(NC(=O)c3ccc(Cl)cc3)sc(=O)c2cc1OC nan
16010496 26118 None 1 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 6 0.6 Cc1ccc2ncc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c(=O)n2c1 nan
CHEMBL1356009 26118 None 1 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 6 0.6 Cc1ccc2ncc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c(=O)n2c1 nan
2140949 26119 None 9 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 7 4.8 COc1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1OC nan
CHEMBL1356037 26119 None 9 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 7 4.8 COc1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1OC nan
2137373 27264 None 11 Human Functional pPotency = 5 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 7 4.5 Cc1cccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccccc23)c1C nan
CHEMBL1366864 27264 None 11 Human Functional pPotency = 5 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 7 4.5 Cc1cccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccccc23)c1C nan
16027547 27552 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 8 4.5 CC(C)CC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CCCCC4)sc3n2)cc1 nan
CHEMBL1369113 27552 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 8 4.5 CC(C)CC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CCCCC4)sc3n2)cc1 nan
16009802 27886 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 5 4.9 CCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
CHEMBL1371530 27886 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 5 4.9 CCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
17581362 28842 None 6 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1cccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)c1 nan
CHEMBL1379032 28842 None 6 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1cccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)c1 nan
4875840 29645 None 3 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 2 4 2.5 COc1ccc(CNC(=O)CN2C(=O)NC(C)(c3cccc(Br)c3)C2=O)cc1 nan
CHEMBL1386021 29645 None 3 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 2 4 2.5 COc1ccc(CNC(=O)CN2C(=O)NC(C)(c3cccc(Br)c3)C2=O)cc1 nan
1486264 30013 None 11 Human Functional pPotency = 5 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 Cc1ccc(Sc2ccc(NC(=O)c3ccc(S(C)(=O)=O)cc3Cl)cc2)cc1 nan
CHEMBL1388862 30013 None 11 Human Functional pPotency = 5 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 Cc1ccc(Sc2ccc(NC(=O)c3ccc(S(C)(=O)=O)cc3Cl)cc2)cc1 nan
2810230 30443 None 3 Human Functional pPotency = 5 5.0 2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 1 4 3.9 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)C1CCC1 nan
CHEMBL1392489 30443 None 3 Human Functional pPotency = 5 5.0 2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 1 4 3.9 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)C1CCC1 nan
16012884 30924 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 7 3.1 COc1ccc(-n2ncc3c2ncn2nc(Cc4ccccc4)nc32)cc1 nan
CHEMBL1397962 30924 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 7 3.1 COc1ccc(-n2ncc3c2ncn2nc(Cc4ccccc4)nc32)cc1 nan
16021838 30954 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cccc(Cl)c2C)c(-c2ccccc2)n1 nan
CHEMBL1398407 30954 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cccc(Cl)c2C)c(-c2ccccc2)n1 nan
2135605 31131 None 10 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 4.6 c1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
CHEMBL1400053 31131 None 10 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 4.6 c1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
15990902 31854 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 2 3 5.7 Cc1cc(C)cc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
CHEMBL1406771 31854 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 2 3 5.7 Cc1cc(C)cc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
963186 32282 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 3 4.2 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)cc1 nan
CHEMBL1410023 32282 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 3 4.2 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)cc1 nan
15989908 32284 None 7 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1410062 32284 None 7 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
15988850 32385 None 7 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 3.6 O=C(Nc1ccc(F)cc1F)c1cc(-c2ccc3c(c2)OCO3)on1 nan
CHEMBL1410908 32385 None 7 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 3.6 O=C(Nc1ccc(F)cc1F)c1cc(-c2ccc3c(c2)OCO3)on1 nan
1128972 32493 None 6 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 0 5 4.3 CCOC(=O)CSc1nc(-c2ccccc2)cc(C(F)(F)F)c1C#N nan
CHEMBL1411854 32493 None 6 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 0 5 4.3 CCOC(=O)CSc1nc(-c2ccccc2)cc(C(F)(F)F)c1C#N nan
3361436 34264 None 0 Human Functional pPotency = 5 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 4 4 4.2 Cc1ccc(NC(=S)NC(=O)c2ccccc2)cc1NC(=S)NC(=O)c1ccccc1 nan
CHEMBL1426572 34264 None 0 Human Functional pPotency = 5 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 4 4 4.2 Cc1ccc(NC(=S)NC(=O)c2ccccc2)cc1NC(=S)NC(=O)c1ccccc1 nan
1627636 34943 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 6 1.6 NN=C(S)Nc1cccc(-c2nnc(S)o2)c1 nan
CHEMBL1432353 34943 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 6 1.6 NN=C(S)Nc1cccc(-c2nnc(S)o2)c1 nan
8087251 35095 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccc(F)cc2)CC1 nan
CHEMBL1433615 35095 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccc(F)cc2)CC1 nan
16023146 35254 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 7 4.9 CCOc1ccc(CNC(=O)CSc2nnc(C)c3c(C)n(-c4ccc(Cl)cc4)nc23)cc1 nan
CHEMBL1435835 35254 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 7 4.9 CCOc1ccc(CNC(=O)CSc2nnc(C)c3c(C)n(-c4ccc(Cl)cc4)nc23)cc1 nan
1741544 37672 None 9 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccccc1C(=O)Nc1ccc2oc(-c3cccc4c(Br)cccc34)nc2c1 nan
CHEMBL1457270 37672 None 9 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccccc1C(=O)Nc1ccc2oc(-c3cccc4c(Br)cccc34)nc2c1 nan
2136370 38158 None 1 Human Functional pPotency = 5 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 3.3 CCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccccc12 nan
CHEMBL1461369 38158 None 1 Human Functional pPotency = 5 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 3.3 CCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccccc12 nan
3594053 39581 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Cl)c1 nan
CHEMBL1473447 39581 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Cl)c1 nan
16241285 40498 None 1 Human Functional pPotency = 5 5.0 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 2.3 CN(C)C=O.CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
CHEMBL1482781 40498 None 1 Human Functional pPotency = 5 5.0 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 2.3 CN(C)C=O.CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
1241177 41287 None 8 Human Functional pPotency = 5 5.0 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 0 8 2.4 c1ccc(COn2nnc3ccccc32)c(COn2nnc3ccccc32)c1 nan
CHEMBL1489236 41287 None 8 Human Functional pPotency = 5 5.0 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 0 8 2.4 c1ccc(COn2nnc3ccccc32)c(COn2nnc3ccccc32)c1 nan
16009541 42012 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccc(F)cc4)cc3)cc(=O)n12 nan
CHEMBL1495115 42012 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccc(F)cc4)cc3)cc(=O)n12 nan
2978485 42732 None 7 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 2 4.1 CCC(C)NC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
CHEMBL1501669 42732 None 7 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 2 4.1 CCC(C)NC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
7514097 42779 None 7 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 4 6 2.2 O=C(O)CCNc1ccc(NCCC(=O)O)c2c1C(=O)c1ccccc1C2=O nan
CHEMBL1502018 42779 None 7 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 4 6 2.2 O=C(O)CCNc1ccc(NCCC(=O)O)c2c1C(=O)c1ccccc1C2=O nan
5777938 42874 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 10 1 8 4.1 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1502864 42874 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 10 1 8 4.1 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
1256983 43606 None 10 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 3 5.3 O=C(Nc1ccc(F)cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
CHEMBL1509228 43606 None 10 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 3 5.3 O=C(Nc1ccc(F)cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
16017574 43939 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 8 1 6 2.5 CCCCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
CHEMBL1512435 43939 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 8 1 6 2.5 CCCCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
15988274 44040 None 3 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
CHEMBL1513838 44040 None 3 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
4921215 44195 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 2 4 6.7 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)Nc3ccc(C)c(C)c3)sc2n1 nan
CHEMBL1516149 44195 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 2 4 6.7 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)Nc3ccc(C)c(C)c3)sc2n1 nan
135466071 46270 None 1 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 6 4.5 CCc1cc2c(s1)N1Cc3ccccc3C(C(=O)c3cccc([N+](=O)[O-])c3)=C1NC2=O nan
CHEMBL1535161 46270 None 1 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 6 4.5 CCc1cc2c(s1)N1Cc3ccccc3C(C(=O)c3cccc([N+](=O)[O-])c3)=C1NC2=O nan
16024942 48273 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.7 CCc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1553067 48273 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.7 CCc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16015892 48287 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(-c2nc3cc(NC(=O)COc4ccc(C)c(C)c4)ccc3o2)cc1 nan
CHEMBL1553238 48287 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(-c2nc3cc(NC(=O)COc4ccc(C)c(C)c4)ccc3o2)cc1 nan
16028168 48956 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(F)c3)cc21 nan
CHEMBL1560108 48956 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(F)c3)cc21 nan
16009056 49410 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 3.7 COC(=O)c1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(C(=O)OC)c1 nan
CHEMBL1564251 49410 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 3.7 COC(=O)c1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(C(=O)OC)c1 nan
626021 50358 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 4 3.0 CNC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
CHEMBL1572204 50358 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 4 3.0 CNC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
2462898 50781 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 0 5 3.4 COc1ccc(C(C)=O)cc1COc1ncnc2ccccc12 nan
CHEMBL1576381 50781 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 0 5 3.4 COc1ccc(C(C)=O)cc1COc1ncnc2ccccc12 nan
16024893 52429 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 4.2 COc1ccc(OC)c(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
CHEMBL1590399 52429 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 4.2 COc1ccc(OC)c(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
16010832 52460 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.0 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3cccnc32)cc1C nan
CHEMBL1590845 52460 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.0 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3cccnc32)cc1C nan
16019294 52544 None 10 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 1 8 5.2 Cc1cc(C)cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)c1 nan
CHEMBL1591857 52544 None 10 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 1 8 5.2 Cc1cc(C)cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)c1 nan
3854561 52621 None 12 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 N#Cc1c(C(F)(F)F)cc(-c2ccc(F)cc2)nc1SCC(=O)Nc1ccccc1 nan
CHEMBL1592912 52621 None 12 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 N#Cc1c(C(F)(F)F)cc(-c2ccc(F)cc2)nc1SCC(=O)Nc1ccccc1 nan
16018208 53524 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
CHEMBL1601478 53524 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
16025642 53676 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 6 1 6 5.9 Cc1cccc(C)c1NC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
CHEMBL1603009 53676 None 5 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 6 1 6 5.9 Cc1cccc(C)c1NC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
4402705 54751 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 8 -0.5 CN1C(=O)C(=NNc2cccc(S(=O)(=O)N3CCOCC3)c2)C(=O)N(C)C1=O nan
CHEMBL1611899 54751 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 8 -0.5 CN1C(=O)C(=NNc2cccc(S(=O)(=O)N3CCOCC3)c2)C(=O)N(C)C1=O nan
16018210 54765 None 2 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 4 5.8 Cc1ccccc1NC(=O)c1oc2c(c1C)-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
CHEMBL1612043 54765 None 2 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 4 5.8 Cc1ccccc1NC(=O)c1oc2c(c1C)-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
2795741 79911 None 2 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 5 5.4 Cc1nc(-c2ccc(S(=O)(=O)Nc3ccc(Br)cc3Cl)s2)cs1 nan
CHEMBL212314 79911 None 2 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 5 5.4 Cc1nc(-c2ccc(S(=O)(=O)Nc3ccc(Br)cc3Cl)s2)cs1 nan
3127110 107803 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 1 8 2.9 C/C(=N\CCCn1ccnc1)c1c(C)nn(-c2ccc([N+](=O)[O-])cc2)c1O nan
CHEMBL3191381 107803 None 8 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 1 8 2.9 C/C(=N\CCCn1ccnc1)c1c(C)nn(-c2ccc([N+](=O)[O-])cc2)c1O nan
1528721 108410 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 3.4 CC(=O)/N=c1\scc(-c2ccccc2)n1-c1cccc(O)c1 nan
CHEMBL3198106 108410 None 4 Human Functional pPotency = 5 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 3.4 CC(=O)/N=c1\scc(-c2ccccc2)n1-c1cccc(O)c1 nan
414 3382 None 22 Human Functional pPotency = 5.0 5.0 -1445 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
93205 3382 None 22 Human Functional pPotency = 5.0 5.0 -1445 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
CHEMBL139000 3382 None 22 Human Functional pPotency = 5.0 5.0 -1445 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
24818570 21210 None 0 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 3 4 3.8 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)cc1 nan
CHEMBL1312949 21210 None 0 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 3 4 3.8 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)cc1 nan
3138147 21679 None 9 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 0 5 5.7 O=C(CSc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1)c1ccccc1 nan
CHEMBL1318270 21679 None 9 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 0 5 5.7 O=C(CSc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1)c1ccccc1 nan
5428505 23073 None 25 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 0 1 3 3.3 O=c1oc2cc(O)c(Cl)cc2c2ccccc12 nan
CHEMBL1330383 23073 None 25 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 0 1 3 3.3 O=c1oc2cc(O)c(Cl)cc2c2ccccc12 nan
5913370 24017 None 4 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 6 1 5 2.8 COCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1337918 24017 None 4 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 6 1 5 2.8 COCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
3694202 24365 None 16 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Cl)c2)no1 nan
CHEMBL1341012 24365 None 16 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Cl)c2)no1 nan
7190321 24740 None 11 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 7 2.6 O=C(CSc1ccc2nnc(-c3cccs3)n2n1)N1CCCC1 nan
CHEMBL1344120 24740 None 11 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 7 2.6 O=C(CSc1ccc2nnc(-c3cccs3)n2n1)N1CCCC1 nan
661441 24786 None 5 Human Functional pPotency = 5.0 5.0 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1344527 24786 None 5 Human Functional pPotency = 5.0 5.0 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1530959 24786 None 5 Human Functional pPotency = 5.0 5.0 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
16017580 25321 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 7 2.9 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Cl)s1 nan
CHEMBL1349094 25321 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 7 2.9 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Cl)s1 nan
3239502 26977 None 7 Human Functional pPotency = 5.0 5.0 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 9 0.3 COc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
CHEMBL1364442 26977 None 7 Human Functional pPotency = 5.0 5.0 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 9 0.3 COc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
7189863 29340 None 9 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.9 O=C(Nc1nc2cc3c(cc2s1)OCO3)c1ccc(N2C(=O)CCC2=O)cc1 nan
CHEMBL1383330 29340 None 9 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.9 O=C(Nc1nc2cc3c(cc2s1)OCO3)c1ccc(N2C(=O)CCC2=O)cc1 nan
16189478 29374 None 1 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 0 6 2.2 CCCCN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1383621 29374 None 1 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 0 6 2.2 CCCCN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
2457625 30337 None 0 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 7 -0.0 CN(CC(=O)c1c(N)n(C)c(=O)n(C)c1=O)c1ccccc1 nan
CHEMBL1391543 30337 None 0 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 7 -0.0 CN(CC(=O)c1c(N)n(C)c(=O)n(C)c1=O)c1ccccc1 nan
686152 30513 None 34 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1393131 30513 None 34 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1576064 30513 None 34 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
16009717 30813 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 Fc1ccc(CNc2nc3c(-c4ccc(F)cc4)nnn3c3ccccc23)cc1 nan
CHEMBL1396454 30813 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 Fc1ccc(CNc2nc3c(-c4ccc(F)cc4)nnn3c3ccccc23)cc1 nan
24892133 30994 None 8 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 11 1.7 COc1ccccc1-c1nc(SCC(=O)Nc2cc(C)on2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1398694 30994 None 8 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 11 1.7 COc1ccccc1-c1nc(SCC(=O)Nc2cc(C)on2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
1115170 33186 None 10 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 5 4.8 Cc1cccc(OCC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)c1 nan
CHEMBL1417596 33186 None 10 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 5 4.8 Cc1cccc(OCC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)c1 nan
15988646 35386 None 1 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 4.9 COc1ccccc1NC(=O)c1sc(-c2ccc(Cl)cc2)cc1N nan
CHEMBL1437533 35386 None 1 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 4.9 COc1ccccc1NC(=O)c1sc(-c2ccc(Cl)cc2)cc1N nan
1341231 35502 None 7 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 5 5.5 COc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
CHEMBL1438558 35502 None 7 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 5 5.5 COc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
2999623 36600 None 4 Human Functional pPotency = 5.0 5.0 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 9 0 8 2.9 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(CCC(=O)OCc1c(C)noc1C)n2C nan
CHEMBL1448461 36600 None 4 Human Functional pPotency = 5.0 5.0 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 9 0 8 2.9 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(CCC(=O)OCc1c(C)noc1C)n2C nan
2609971 38770 None 3 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 7 3.2 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccccc2c1=O nan
CHEMBL1466287 38770 None 3 Human Functional pPotency = 5.0 5.0 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 7 3.2 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccccc2c1=O nan
16024828 41681 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5F)CC4)ccc3c2)CC1 nan
CHEMBL1492051 41681 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5F)CC4)ccc3c2)CC1 nan
3276076 42378 None 6 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 7 3.1 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
CHEMBL1498535 42378 None 6 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 7 3.1 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
3494087 43822 None 2 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 7 2.0 Cc1sc2ncnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)c2c1C nan
CHEMBL1511159 43822 None 2 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 7 2.0 Cc1sc2ncnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)c2c1C nan
22513173 44145 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 7 2.0 COc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccccc4F)ncn3n2)cc1 nan
CHEMBL1515462 44145 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 7 2.0 COc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccccc4F)ncn3n2)cc1 nan
16025349 44685 None 9 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.6 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccccc1)S2(=O)=O)Nc1ccccc1 nan
CHEMBL1520822 44685 None 9 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.6 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccccc1)S2(=O)=O)Nc1ccccc1 nan
16017252 45939 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.1 Cc1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
CHEMBL1532051 45939 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.1 Cc1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
659886 46245 None 9 Human Functional pPotency = 5.0 5.0 1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 5 5.4 CCc1ccccc1NC(=O)CSc1nc2c(c(-c3ccco3)c1C#N)CCCC2 nan
CHEMBL1534846 46245 None 9 Human Functional pPotency = 5.0 5.0 1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 5 5.4 CCc1ccccc1NC(=O)CSc1nc2c(c(-c3ccco3)c1C#N)CCCC2 nan
790785 46285 None 8 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 3 2 3 3.5 CCCc1c(C)nc2ccc(C(=O)O)cc2c1S nan
CHEMBL1535349 46285 None 8 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 3 2 3 3.5 CCCc1c(C)nc2ccc(C(=O)O)cc2c1S nan
3767937 46726 None 9 Human Functional pPotency = 5.0 5.0 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 6 5.6 N#Cc1c(N)nc(SCC(=O)C23CC4CC(CC(C4)C2)C3)c(C#N)c1-c1ccc(Cl)cc1 nan
CHEMBL1539280 46726 None 9 Human Functional pPotency = 5.0 5.0 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 6 5.6 N#Cc1c(N)nc(SCC(=O)C23CC4CC(CC(C4)C2)C3)c(C#N)c1-c1ccc(Cl)cc1 nan
24792845 50400 None 2 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 1.3 Cc1nn(CC(=O)NCC2CCCO2)c(=O)c2cc3ccccc3n12 nan
CHEMBL1572639 50400 None 2 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 1.3 Cc1nn(CC(=O)NCC2CCCO2)c(=O)c2cc3ccccc3n12 nan
319257 50418 None 2 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 4 2 2 3.0 C=C(C)C(=O)Nc1ccc(NC(C)C)cc1 nan
CHEMBL1572793 50418 None 2 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 4 2 2 3.0 C=C(C)C(=O)Nc1ccc(NC(C)C)cc1 nan
2100389 51713 None 3 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 2.5 O=C(COc1ncnc2scc(-c3ccccc3)c12)NCCN1C(=O)CSC1=O nan
CHEMBL1584231 51713 None 3 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 2.5 O=C(COc1ncnc2scc(-c3ccccc3)c12)NCCN1C(=O)CSC1=O nan
16019541 52458 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 8 5.1 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(Nc2ccc(C)c(C)c2)c2sccc23)c1 nan
CHEMBL1590799 52458 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 8 5.1 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(Nc2ccc(C)c(C)c2)c2sccc23)c1 nan
16025640 52516 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 5.6 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
CHEMBL1591452 52516 None 5 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 5.6 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
1189472 52971 None 10 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 2.9 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCN1CCOCC1 nan
CHEMBL1596394 52971 None 10 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 2.9 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCN1CCOCC1 nan
1115820 54715 None 16 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 6 5.4 COc1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1611566 54715 None 16 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 6 5.4 COc1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
9581898 72612 None 9 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 5 2.0 Cc1cccc(C(=O)N/N=C2\CS(=O)(=O)N(C)c3ccsc32)c1 nan
CHEMBL1992883 72612 None 9 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 5 2.0 Cc1cccc(C(=O)N/N=C2\CS(=O)(=O)N(C)c3ccsc32)c1 nan
17584449 109168 None 6 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 0 7 2.6 COc1cc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2c2ccccc2)cc(OC)c1OC nan
CHEMBL3213657 109168 None 6 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 0 7 2.6 COc1cc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2c2ccccc2)cc(OC)c1OC nan
CHEMBL1411485 211223 None 0 Human Functional pPotency = 5.0 5.0 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL None None None None nan
377 2758 None 42 Human Functional pPotency = 5.9 5.9 -371 10
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
425 2758 None 42 Human Functional pPotency = 5.9 5.9 -371 10
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
448222 2758 None 42 Human Functional pPotency = 5.9 5.9 -371 10
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
CHEMBL464859 2758 None 42 Human Functional pPotency = 5.9 5.9 -371 10
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
135415429 41319 None 4 Human Functional pPotency = 5.9 5.9 2 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 8 1 9 4.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(SCc1nc(O)c3sccc3n1)n2CC nan
CHEMBL1489478 41319 None 4 Human Functional pPotency = 5.9 5.9 2 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 8 1 9 4.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(SCc1nc(O)c3sccc3n1)n2CC nan
6076 107322 None 47 Human Functional pPotency = 5.9 5.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
CHEMBL1363683 107322 None 47 Human Functional pPotency = 5.9 5.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
CHEMBL316966 107322 None 47 Human Functional pPotency = 5.9 5.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
20923189 19801 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 0 6 2.1 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1 nan
CHEMBL1301594 19801 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 0 6 2.1 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1 nan
613860 20220 None 8 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 6 2.9 Cc1noc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)c1C nan
CHEMBL1305078 20220 None 8 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 6 2.9 Cc1noc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)c1C nan
2480606 20430 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 2 7 0.6 Cc1cccc(NCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
CHEMBL1306773 20430 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 2 7 0.6 Cc1cccc(NCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
224672 22716 None 30 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 3 1 3 3.1 O=C(O)CSc1ccnc2cc(Cl)ccc12 nan
CHEMBL1327484 22716 None 30 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 3 1 3 3.1 O=C(O)CSc1ccnc2cc(Cl)ccc12 nan
2384232 22784 None 25 Human Functional pPotency = 4.9 4.9 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 4.2 Cc1sc2ncnc(Sc3ccccc3C(=O)O)c2c1C nan
CHEMBL1327902 22784 None 25 Human Functional pPotency = 4.9 4.9 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 4.2 Cc1sc2ncnc(Sc3ccccc3C(=O)O)c2c1C nan
1442817 23260 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.6 Cc1nnc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)s1 nan
CHEMBL1331799 23260 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.6 Cc1nnc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)s1 nan
6103449 23881 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 0 3 4.0 CCN1/C(=C2\C(=O)N(C)C(=S)N2c2ccccc2)C=Cc2ccccc21 nan
CHEMBL1336606 23881 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 0 3 4.0 CCN1/C(=C2\C(=O)N(C)C(=S)N2c2ccccc2)C=Cc2ccccc21 nan
662886 23914 None 5 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 7 3.5 Brc1ccc(-c2nn3c(-c4ccco4)nnc3s2)o1 nan
CHEMBL1336927 23914 None 5 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 7 3.5 Brc1ccc(-c2nn3c(-c4ccco4)nnc3s2)o1 nan
16011044 26703 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)NC(=O)c2ccccc2S3)cc1 nan
CHEMBL1362040 26703 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)NC(=O)c2ccccc2S3)cc1 nan
826482 26825 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 250 1 2 6 1.8 CC1(C)Cc2c(sc3ncnc(NN)c23)CO1 nan
CHEMBL1363060 26825 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 250 1 2 6 1.8 CC1(C)Cc2c(sc3ncnc(NN)c23)CO1 nan
16024887 27233 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 4.6 CCOc1ccccc1CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1366554 27233 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 4.6 CCOc1ccccc1CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
3207679 29161 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1cccc2cc(C#N)c(SCC(=O)NCc3cccs3)nc12 nan
CHEMBL1381650 29161 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1cccc2cc(C#N)c(SCC(=O)NCc3cccs3)nc12 nan
2445448 29652 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 0 7 1.4 COc1ccc(C(C)=O)cc1Cn1cnc2c(cnn2C)c1=O nan
CHEMBL1386075 29652 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 0 7 1.4 COc1ccc(C(C)=O)cc1Cn1cnc2c(cnn2C)c1=O nan
15988012 30011 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1388847 30011 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
2917979 30091 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 9 4.0 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)nc1C nan
CHEMBL1389475 30091 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 9 4.0 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)nc1C nan
686152 30513 None 34 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1393131 30513 None 34 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1576064 30513 None 34 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
15987889 33222 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 8 1 4 5.4 CCN(CC)CC(C)CNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1417926 33222 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 8 1 4 5.4 CCN(CC)CC(C)CNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
20904552 33820 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 8 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
CHEMBL1422972 33820 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 8 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
2375468 34942 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 -0.2 Cn1c(N)c(C(=O)COc2ccc(C#N)cc2)c(=O)n(C)c1=O nan
CHEMBL1432350 34942 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 -0.2 Cn1c(N)c(C(=O)COc2ccc(C#N)cc2)c(=O)n(C)c1=O nan
16024881 35087 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 4 2.6 CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1433473 35087 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 4 2.6 CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
15991045 35096 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 3 1 3 7.0 Cc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
CHEMBL1433636 35096 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 3 1 3 7.0 Cc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
16015278 35183 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 6 5.3 CC(=O)c1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4)c3C)nc2C)cc1 nan
CHEMBL1434956 35183 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 6 5.3 CC(=O)c1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4)c3C)nc2C)cc1 nan
5078950 35542 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1438931 35542 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
5310383 35977 None 10 Human Functional pPotency = 4.9 4.9 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 0.3 O=C(Cn1cnc2c(nnn2-c2ccccc2)c1=O)NCC1CCCO1 nan
CHEMBL1442757 35977 None 10 Human Functional pPotency = 4.9 4.9 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 0.3 O=C(Cn1cnc2c(nnn2-c2ccccc2)c1=O)NCC1CCCO1 nan
948433 35990 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 1 4 3.7 COc1ccc(CNC(=O)CSc2cccc3cccnc23)cc1 nan
CHEMBL1442938 35990 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 1 4 3.7 COc1ccc(CNC(=O)CSc2cccc3cccnc23)cc1 nan
16019658 36252 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 7 3.2 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1C nan
CHEMBL1445403 36252 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 7 3.2 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1C nan
3208298 38837 None 3 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 3.7 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1nccs1)OCO3 nan
CHEMBL1466770 38837 None 3 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 3.7 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1nccs1)OCO3 nan
6623284 39490 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 0 7 3.0 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCCC2)s1 nan
CHEMBL1472373 39490 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 0 7 3.0 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCCC2)s1 nan
5302642 39619 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 2 4 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2)cc1 nan
CHEMBL1474011 39619 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 2 4 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2)cc1 nan
1203028 39645 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 2 8 0.0 CC(=O)Nc1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1474423 39645 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 2 8 0.0 CC(=O)Nc1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
15988309 39979 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 8 2.1 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
CHEMBL1478365 39979 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 8 2.1 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
1387364 40816 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1485560 40816 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1576237 40816 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
4238273 40870 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 6 2.9 Cn1c(SCC(=O)c2ccc3c(c2)NC(=O)CO3)nc2ccccc21 nan
CHEMBL1485997 40870 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 6 2.9 Cn1c(SCC(=O)c2ccc3c(c2)NC(=O)CO3)nc2ccccc21 nan
16025632 41770 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
CHEMBL1492743 41770 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
1252362 42541 None 11 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 5 5.2 COc1ccc(-n2c(-c3cccc(OC)c3)nc(=S)c3c2CCCC3)cc1 nan
CHEMBL1499911 42541 None 11 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 5 5.2 COc1ccc(-n2c(-c3cccc(OC)c3)nc(=S)c3c2CCCC3)cc1 nan
3173852 42633 None 4 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 4 3.8 CNC(=S)N(Cc1ccc(OC)cc1)Cc1cc2cc(C)ccc2nc1O nan
CHEMBL1500673 42633 None 4 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 4 3.8 CNC(=S)N(Cc1ccc(OC)cc1)Cc1cc2cc(C)ccc2nc1O nan
16189472 43269 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 2.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)Nc1cccnc1Cl)C(=O)CO2 nan
CHEMBL1506287 43269 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 2.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)Nc1cccnc1Cl)C(=O)CO2 nan
20953562 43607 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 7 2.9 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)ncn3n2)cc1 nan
CHEMBL1509249 43607 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 7 2.9 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)ncn3n2)cc1 nan
20923188 43774 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 6 2.4 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccccc1 nan
CHEMBL1510719 43774 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 6 2.4 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccccc1 nan
16025766 44049 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 4 5.8 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccccc3Cl)CC2)s1 nan
CHEMBL1514065 44049 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 4 5.8 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccccc3Cl)CC2)s1 nan
5206706 44059 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.8 CN(C)c1ccc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)cc1 nan
CHEMBL1514233 44059 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.8 CN(C)c1ccc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)cc1 nan
15988349 44176 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccc(F)cc3)c2n1 nan
CHEMBL1515965 44176 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccc(F)cc3)c2n1 nan
4458977 44402 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 11 0.7 CCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1518407 44402 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 11 0.7 CCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
15989681 44500 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 7 1 7 4.1 COc1cc2c(=O)n(Cc3ccccc3Cl)c(=O)n(CC(=O)Nc3ccc(C)c(C)c3)c2cc1OC nan
CHEMBL1519224 44500 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 7 1 7 4.1 COc1cc2c(=O)n(Cc3ccccc3Cl)c(=O)n(CC(=O)Nc3ccc(C)c(C)c3)c2cc1OC nan
16019398 45212 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 0 9 2.6 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Cl)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1525727 45212 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 0 9 2.6 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Cl)cc4)nnn3c3ccsc23)CC1 nan
16009804 45562 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 7 4.3 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1C nan
CHEMBL1528709 45562 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 7 4.3 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1C nan
2808993 45676 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 0 5 3.4 CCc1nc2ccccc2nc1N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 nan
CHEMBL1529717 45676 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 0 5 3.4 CCc1nc2ccccc2nc1N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 nan
588806 46483 None 17 Human Functional pPotency = 4.9 4.9 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 4 1 4 2.5 Cc1nc(SCCC(=O)O)c2ccccc2n1 nan
CHEMBL1537195 46483 None 17 Human Functional pPotency = 4.9 4.9 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 4 1 4 2.5 Cc1nc(SCCC(=O)O)c2ccccc2n1 nan
2810142 47199 None 3 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 5 3.6 O=C(Nc1nc2ccsc2c(=O)s1)c1ccc(Cl)cc1 nan
CHEMBL1543276 47199 None 3 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 5 3.6 O=C(Nc1nc2ccsc2c(=O)s1)c1ccc(Cl)cc1 nan
2158355 47620 None 4 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 7 0 7 1.6 COCCN(CCOC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1546597 47620 None 4 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 7 0 7 1.6 COCCN(CCOC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
1304353 48299 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 3 5.4 Cc1ccc(-c2sc(C(=O)Nc3ccc(Br)cc3)cc2CC(=O)O)cc1 nan
CHEMBL1553391 48299 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 3 5.4 Cc1ccc(-c2sc(C(=O)Nc3ccc(Br)cc3)cc2CC(=O)O)cc1 nan
3725217 48710 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 2 2 6 2.1 CC(C)C1Cc2c(sc3ncnc(NN)c23)CO1 nan
CHEMBL1557963 48710 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 2 2 6 2.1 CC(C)C1Cc2c(sc3ncnc(NN)c23)CO1 nan
16017731 49494 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 5 1.5 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)NCCc1ccccc1 nan
CHEMBL1565042 49494 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 5 1.5 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)NCCc1ccccc1 nan
7184630 51600 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1ccccc1CNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1583340 51600 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1ccccc1CNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
24856176 52164 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 4 3.3 CN(CC(=O)Nc1ccccc1Cl)C(=O)COC(=O)Cc1c(F)cccc1Cl nan
CHEMBL1587934 52164 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 4 3.3 CN(CC(=O)Nc1ccccc1Cl)C(=O)COC(=O)Cc1c(F)cccc1Cl nan
16033298 52424 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 5.5 Cc1c(C(=O)NCc2ccc(OC(C)C)cc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1590310 52424 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 5.5 Cc1c(C(=O)NCc2ccc(OC(C)C)cc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
16010771 52588 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 6 3.5 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(Cc2ccccc2Cl)c(=O)c2cccnc21 nan
CHEMBL1592455 52588 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 6 3.5 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(Cc2ccccc2Cl)c(=O)c2cccnc21 nan
16029563 52714 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 6 4.2 COc1ccc(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(C)ccc32)cc1Cl nan
CHEMBL1594200 52714 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 6 4.2 COc1ccc(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(C)ccc32)cc1Cl nan
18553656 52906 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 9 1.0 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(CC(C)(C)C)nc2n(C)c1=O nan
CHEMBL1595812 52906 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 9 1.0 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(CC(C)(C)C)nc2n(C)c1=O nan
773677 53538 None 22 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 1 1 4 3.9 Cc1ccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCC4)cc1 nan
CHEMBL1601668 53538 None 22 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 1 1 4 3.9 Cc1ccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCC4)cc1 nan
1414561 53908 None 26 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 5 4.0 C=CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1604975 53908 None 26 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 5 4.0 C=CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
135693221 54996 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1359119 54996 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1615929 54996 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
6476987 55363 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL1385494 55363 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL1618897 55363 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
135502886 121741 None 18 Human Functional pPotency = 4.9 4.9 -2 4
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 221 1 2 4 1.1 NC(=S)c1cc2ccc(O)cc2oc1=O nan
CHEMBL358644 121741 None 18 Human Functional pPotency = 4.9 4.9 -2 4
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 221 1 2 4 1.1 NC(=S)c1cc2ccc(O)cc2oc1=O nan
24360 205802 None 64 Human Functional pPotency = 4.9 4.9 -12 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 6 2.1 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
CHEMBL65 205802 None 64 Human Functional pPotency = 4.9 4.9 -12 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 6 2.1 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
5359 210168 None 51 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 4 1 3 3.2 CC(C(=O)O)c1ccc(C(=O)c2cccs2)cc1 nan
CHEMBL956 210168 None 51 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 4 1 3 3.2 CC(C(=O)O)c1ccc(C(=O)c2cccs2)cc1 nan
2647611 52668 None 10 Human Functional pPotency = 3.9 3.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 6 3.0 CC(=O)c1c(C)[nH]c(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)c1C nan
CHEMBL1593590 52668 None 10 Human Functional pPotency = 3.9 3.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 6 3.0 CC(=O)c1c(C)[nH]c(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)c1C nan
126054 43951 None 34 Human Functional pPotency = 5.9 5.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 11 7 12 -0.0 NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4c3ncn4[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1 nan
CHEMBL1512545 43951 None 34 Human Functional pPotency = 5.9 5.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 11 7 12 -0.0 NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4c3ncn4[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1 nan
380 1287 None 37 Human Functional pPotency = 4.9 4.9 -7413 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
657378 1287 None 37 Human Functional pPotency = 4.9 4.9 -7413 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
CHEMBL68738 1287 None 37 Human Functional pPotency = 4.9 4.9 -7413 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
191 13179 None 39 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 9 -2.0 Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
CHEMBL11909 13179 None 39 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 9 -2.0 Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
15988009 19718 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1300978 19718 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
1246444 19765 None 10 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 2 8 2.6 COc1cc(OC)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)cc1OC nan
CHEMBL1301318 19765 None 10 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 2 8 2.6 COc1cc(OC)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)cc1OC nan
5733367 19803 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 9 1 6 3.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C2c2ccc(F)cc2)cc1C nan
CHEMBL1301612 19803 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 9 1 6 3.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C2c2ccc(F)cc2)cc1C nan
3207945 19843 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 5 2.9 CCOC(=O)CNC(=O)CSc1nc2c(C)cccc2cc1CC nan
CHEMBL1302034 19843 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 5 2.9 CCOC(=O)CNC(=O)CSc1nc2c(C)cccc2cc1CC nan
2978035 20069 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 4 1.3 O=C(CN1C(=O)c2ccc(Br)cc2C1=O)NCC1CCCO1 nan
CHEMBL1303768 20069 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 4 1.3 O=C(CN1C(=O)c2ccc(Br)cc2C1=O)NCC1CCCO1 nan
16194904 21234 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)CC1 nan
CHEMBL1313100 21234 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)CC1 nan
127136 21349 None 12 Human Functional pPotency = 4.9 4.9 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549067 21349 None 12 Human Functional pPotency = 4.9 4.9 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549068 21349 None 12 Human Functional pPotency = 4.9 4.9 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549069 21349 None 12 Human Functional pPotency = 4.9 4.9 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
CHEMBL1314043 21349 None 12 Human Functional pPotency = 4.9 4.9 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
CHEMBL1556805 21349 None 12 Human Functional pPotency = 4.9 4.9 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
3151367 21386 None 11 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 1.8 CCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
CHEMBL1314339 21386 None 11 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 1.8 CCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
16009645 21472 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 2 5 5.9 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)cc1OCC nan
CHEMBL1315511 21472 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 2 5 5.9 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)cc1OCC nan
16009682 21513 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1cccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)c1 nan
CHEMBL1315996 21513 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1cccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)c1 nan
16023134 21637 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 6 2.4 CNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)C1 nan
CHEMBL1317674 21637 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 6 2.4 CNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)C1 nan
16019581 21672 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 3 0 9 2.7 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1318189 21672 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 3 0 9 2.7 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
16017720 21682 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 0 4 3.1 O=c1c(=O)n(-c2ccccc2)ccn1Cc1cccc(C(F)(F)F)c1 nan
CHEMBL1318320 21682 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 0 4 3.1 O=c1c(=O)n(-c2ccccc2)ccn1Cc1cccc(C(F)(F)F)c1 nan
2458272 21705 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3ccc4c(c3)OCCO4)nc2n1 nan
CHEMBL1318506 21705 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3ccc4c(c3)OCCO4)nc2n1 nan
15988341 21738 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 2 5 5.3 COc1ccc(-c2cc(C(=O)NCCc3ccccc3)c3c(-c4ccccc4)[nH]nc3n2)cc1OC nan
CHEMBL1318769 21738 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 2 5 5.3 COc1ccc(-c2cc(C(=O)NCCc3ccccc3)c3c(-c4ccccc4)[nH]nc3n2)cc1OC nan
3245692 21750 None 7 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.3 c1ccc(CCNc2nc3ccccc3n3nnnc23)cc1 nan
CHEMBL1318873 21750 None 7 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.3 c1ccc(CCNc2nc3ccccc3n3nnnc23)cc1 nan
16009520 22129 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3ccc(NC(=O)c4ccccc4F)cc3)cc(=O)n12 nan
CHEMBL1322132 22129 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3ccc(NC(=O)c4ccccc4F)cc3)cc(=O)n12 nan
1003845 22161 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)c(F)c4)sc3n2)c1 nan
CHEMBL1322400 22161 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)c(F)c4)sc3n2)c1 nan
1021427 22667 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 2 4 4.5 Cn1nc(C(=O)Nc2ccc(Br)cc2)cc1C(=O)Nc1ccc(Br)cc1 nan
CHEMBL1327019 22667 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 2 4 4.5 Cn1nc(C(=O)Nc2ccc(Br)cc2)cc1C(=O)Nc1ccc(Br)cc1 nan
1386649 23473 None 6 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
1386650 23473 None 6 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
CHEMBL1333441 23473 None 6 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
24503354 23619 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 3 2.5 O=C(c1ccc(S(=O)(=O)Nc2ccccc2F)cc1)N1CCC1 nan
CHEMBL1334480 23619 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 3 2.5 O=C(c1ccc(S(=O)(=O)Nc2ccccc2F)cc1)N1CCC1 nan
15988003 23709 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)c(F)c3)nnc12 nan
CHEMBL1335235 23709 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)c(F)c3)nnc12 nan
135416637 24096 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 2 7 5.8 Cc1ccc(C)c(NC(=O)CSc2nc(O)c3c(C(F)(F)F)cc(-c4cccs4)nc3n2)c1 nan
CHEMBL1338446 24096 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 2 7 5.8 Cc1ccc(C)c(NC(=O)CSc2nc(O)c3c(C(F)(F)F)cc(-c4cccs4)nc3n2)c1 nan
1023823 24339 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 4 3.3 NS(=O)(=O)c1c(Sc2ccccc2C(=O)O)ccc2ccccc12 nan
CHEMBL1340736 24339 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 4 3.3 NS(=O)(=O)c1c(Sc2ccccc2C(=O)O)ccc2ccccc12 nan
3420063 24490 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 2 7 3.4 COc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)c(OC)c1 nan
CHEMBL1342030 24490 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 2 7 3.4 COc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)c(OC)c1 nan
2023917 25066 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 3 4 4.5 O=C(NC(=S)Nc1ccccc1C(=O)O)c1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1346887 25066 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 3 4 4.5 O=C(NC(=S)Nc1ccccc1C(=O)O)c1ccc(-c2ccc(Br)cc2)o1 nan
6145649 25156 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 7 1 6 2.9 N#Cc1nc(/C=C/c2ccccc2)oc1NCCCN1CCOCC1 nan
CHEMBL1347564 25156 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 7 1 6 2.9 N#Cc1nc(/C=C/c2ccccc2)oc1NCCCN1CCOCC1 nan
3099832 25215 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 3.7 Cc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)cc1 nan
CHEMBL1348101 25215 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 3.7 Cc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)cc1 nan
16033268 26064 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1cccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
CHEMBL1355268 26064 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1cccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
16004219 26123 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 7 4.6 Brc1ccc(-c2ccc(CNCCSc3nnnn3-c3ccccc3)o2)cc1 nan
CHEMBL1356105 26123 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 7 4.6 Brc1ccc(-c2ccc(CNCCSc3nnnn3-c3ccccc3)o2)cc1 nan
16033294 26135 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 6 5.1 CCOc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1356206 26135 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 6 5.1 CCOc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
16018776 26198 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 6 4.8 Cc1cc2c(cc3c(SCC(=O)Nc4cccc(Cl)c4C)nnc(C)n32)o1 nan
CHEMBL1357046 26198 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 6 4.8 Cc1cc2c(cc3c(SCC(=O)Nc4cccc(Cl)c4C)nnc(C)n32)o1 nan
16014983 26329 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2cccc(C)c2)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1358814 26329 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2cccc(C)c2)c(C#N)c(-c2ccccc2)n1 nan
7190674 26698 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1F nan
CHEMBL1361981 26698 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1F nan
2138626 26782 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1ccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)cc1 nan
CHEMBL1362650 26782 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1ccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)cc1 nan
4152428 27037 None 5 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
CHEMBL1364957 27037 None 5 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
15988005 27194 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 2.6 Cc1ccc(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1366276 27194 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 2.6 Cc1ccc(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
15996111 27286 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 4 4.9 CCOCCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1367087 27286 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 4 4.9 CCOCCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
659844 27372 None 11 Human Functional pPotency = 4.9 4.9 -11 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 8 3.9 CCCCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OCC)cc2)c1C#N nan
CHEMBL1367765 27372 None 11 Human Functional pPotency = 4.9 4.9 -11 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 8 3.9 CCCCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OCC)cc2)c1C#N nan
5287091 27400 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 2 4.7 Cc1ccc2nc(/C(C#N)=C/c3cccc(Br)c3)[nH]c2c1 nan
CHEMBL1367954 27400 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 2 4.7 Cc1ccc2nc(/C(C#N)=C/c3cccc(Br)c3)[nH]c2c1 nan
15991106 27430 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 1 5 6.0 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1C nan
CHEMBL1368193 27430 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 1 5 6.0 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1C nan
3544515 27460 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 6 1 9 2.2 O=C(O)CCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
CHEMBL1368416 27460 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 6 1 9 2.2 O=C(O)CCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
4191572 27529 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 COc1ccccc1Cn1c(=S)[nH]c2ccc(F)cc2c1=O nan
CHEMBL1368980 27529 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 COc1ccccc1Cn1c(=S)[nH]c2ccc(F)cc2c1=O nan
2743471 28471 None 19 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 2 1 4 3.7 CSc1cc(-c2ccc(Cl)cc2)nc(O)c1C#N nan
CHEMBL1375507 28471 None 19 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 2 1 4 3.7 CSc1cc(-c2ccc(Cl)cc2)nc(O)c1C#N nan
1175821 28475 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 0 10 0.7 CC(C)n1c(SCC(=O)N2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1375543 28475 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 0 10 0.7 CC(C)n1c(SCC(=O)N2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
3241220 28513 None 4 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 1.4 O=C(Cn1cnc2c(oc3ccccc32)c1=O)NCC1CCCO1 nan
CHEMBL1375857 28513 None 4 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 1.4 O=C(Cn1cnc2c(oc3ccccc32)c1=O)NCC1CCCO1 nan
5733045 28770 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 5 4.5 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2cccc(Cl)c2)cc1 nan
CHEMBL1378340 28770 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 5 4.5 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2cccc(Cl)c2)cc1 nan
3746307 29293 None 24 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 1 1 5 3.4 Cn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1382865 29293 None 24 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 1 1 5 3.4 Cn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
2939274 29352 None 14 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 7 4.5 CC(C)c1nnc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)s1 nan
CHEMBL1383461 29352 None 14 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 7 4.5 CC(C)c1nnc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)s1 nan
16194976 29425 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)CC1 nan
CHEMBL1384046 29425 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)CC1 nan
15987888 29468 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1384448 29468 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
2944910 29543 None 9 Human Functional pPotency = 4.9 4.9 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 6 4.2 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccnc1)c1cc2ccccc2o1 nan
CHEMBL1385074 29543 None 9 Human Functional pPotency = 4.9 4.9 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 6 4.2 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccnc1)c1cc2ccccc2o1 nan
1928929 29795 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 3 2 7 5.5 Nc1c(C(=O)Nc2nc3ccccc3s2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1387110 29795 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 3 2 7 5.5 Nc1c(C(=O)Nc2nc3ccccc3s2)sc2nc(-c3cccs3)ccc12 nan
2237376 29817 None 14 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 2 8 3.0 CSc1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
CHEMBL1387290 29817 None 14 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 2 8 3.0 CSc1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
2779879 30201 None 17 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 3 4.1 Cc1c(C(=O)c2ccccc2C(=O)O)sc2ccccc12 nan
CHEMBL1390399 30201 None 17 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 3 4.1 Cc1c(C(=O)c2ccccc2C(=O)O)sc2ccccc12 nan
5088202 30699 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cccc(C)c4)sc3n2)cc1 nan
CHEMBL1394959 30699 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cccc(C)c4)sc3n2)cc1 nan
16018778 30794 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4ccc(Cl)cc4)nnc(C)n32)o1 nan
CHEMBL1396136 30794 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4ccc(Cl)cc4)nnc(C)n32)o1 nan
15987656 30858 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 12 1 6 5.8 CCOc1ccc(CCNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1OCC nan
CHEMBL1397047 30858 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 12 1 6 5.8 CCOc1ccc(CCNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1OCC nan
16018052 30880 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 4 3.8 Cc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1397347 30880 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 4 3.8 Cc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
15987604 30899 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1ccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)cc1 nan
CHEMBL1397611 30899 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1ccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)cc1 nan
866239 30952 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 2.9 Cc1ccc(-n2c(=O)[nH]c3sc4c(c3c2=O)CCCC4)cc1 nan
CHEMBL1398397 30952 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 2.9 Cc1ccc(-n2c(=O)[nH]c3sc4c(c3c2=O)CCCC4)cc1 nan
15990870 31109 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 3 5.3 Cc1ccc(C)c(Nc2cc(C(=O)NC3CCCC3)c3ccccc3n2)c1 nan
CHEMBL1399859 31109 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 3 5.3 Cc1ccc(C)c(Nc2cc(C(=O)NC3CCCC3)c3ccccc3n2)c1 nan
20904142 31211 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 0 9 1.3 COc1ccc(N2CCN(C(=O)CCc3nnc4ccc(N5CCOCC5)nn34)CC2)cc1 nan
CHEMBL1400806 31211 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 0 9 1.3 COc1ccc(N2CCN(C(=O)CCc3nnc4ccc(N5CCOCC5)nn34)CC2)cc1 nan
2859630 32015 None 14 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 0.9 O=C(CN1C(=O)c2cccc3cccc(c23)C1=O)NCCN1CCOCC1 nan
CHEMBL1408014 32015 None 14 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 0.9 O=C(CN1C(=O)c2cccc3cccc(c23)C1=O)NCCN1CCOCC1 nan
22553366 32064 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 7 1.5 CCOC(=O)C1CCN(C(=O)Cn2c(=O)c3cccn3c3cccnc32)CC1 nan
CHEMBL1408318 32064 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 7 1.5 CCOC(=O)C1CCN(C(=O)Cn2c(=O)c3cccn3c3cccnc32)CC1 nan
2911470 32739 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 8 3.8 C=CCOc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1413736 32739 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 8 3.8 C=CCOc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
663378 32764 None 5 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 3 0 5 3.4 N#CCCSc1ncnc2c1oc1ccccc12 nan
CHEMBL1413946 32764 None 5 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 3 0 5 3.4 N#CCCSc1ncnc2c1oc1ccccc12 nan
1175547 32849 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 9 2.6 COc1cc(OC)cc(-n2nnnc2SCC(=O)Nc2ccc(C(C)=O)cc2)c1 nan
CHEMBL1414657 32849 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 9 2.6 COc1cc(OC)cc(-n2nnnc2SCC(=O)Nc2ccc(C(C)=O)cc2)c1 nan
2152512 32873 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1ccccc1OC nan
CHEMBL1414820 32873 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1ccccc1OC nan
16033750 32999 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 3 5.8 CC(C)c1ccc(N2C(=O)N(Cc3ccccc3Cl)c3ccccc3S2(=O)=O)cc1 nan
CHEMBL1416012 32999 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 3 5.8 CC(C)c1ccc(N2C(=O)N(Cc3ccccc3Cl)c3ccccc3S2(=O)=O)cc1 nan
1138440 33038 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 10 1.8 CCCn1c(SCC(=O)c2ccc(OC)c(OC)c2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1416338 33038 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 10 1.8 CCCn1c(SCC(=O)c2ccc(OC)c(OC)c2)nc2c1c(=O)n(C)c(=O)n2C nan
135445597 33127 None 17 Human Functional pPotency = 4.9 4.9 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 2 1 6 2.5 CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1417116 33127 None 17 Human Functional pPotency = 4.9 4.9 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 2 1 6 2.5 CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
24892379 33287 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 9 1.7 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3Cl)nc2n(C)c1=O nan
CHEMBL1418535 33287 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 9 1.7 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3Cl)nc2n(C)c1=O nan
24789790 33333 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 0 8 0.8 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3scc(C)n3c2=O)CC1 nan
CHEMBL1418824 33333 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 0 8 0.8 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3scc(C)n3c2=O)CC1 nan
5220580 33432 None 11 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 5 4.0 CC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2Cl)nc1C nan
CHEMBL1419730 33432 None 11 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 5 4.0 CC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2Cl)nc1C nan
3699048 33437 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 2 6 3.5 Cc1ccc[n+](C2C(c3cccs3)C(C#N)=C([C-](C#N)C#N)NC2(O)c2ccccc2)c1 nan
CHEMBL1419826 33437 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 2 6 3.5 Cc1ccc[n+](C2C(c3cccs3)C(C#N)=C([C-](C#N)C#N)NC2(O)c2ccccc2)c1 nan
5790281 33570 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 10 1 7 3.7 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1 nan
CHEMBL1420847 33570 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 10 1 7 3.7 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1 nan
2974740 33578 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 4 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3cccs3)nc12 nan
CHEMBL1420938 33578 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 4 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3cccs3)nc12 nan
824727 33610 None 6 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 2 0 4 2.2 CCOC(=O)c1cc(Br)c(=O)n2ccccc12 nan
CHEMBL1421240 33610 None 6 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 2 0 4 2.2 CCOC(=O)c1cc(Br)c(=O)n2ccccc12 nan
6411582 33715 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 10 2 10 4.3 CCOC(=O)CCCCC(=O)c1[nH]c(O)nc1CSc1nnc2c3cc(Br)ccc3n(C)c2n1 nan
CHEMBL1422131 33715 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 10 2 10 4.3 CCOC(=O)CCCCC(=O)c1[nH]c(O)nc1CSc1nnc2c3cc(Br)ccc3n(C)c2n1 nan
4910054 33760 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 9 1.1 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(CCO)CC4)o3)nnc2c2ccccc12 nan
CHEMBL1422462 33760 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 9 1.1 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(CCO)CC4)o3)nnc2c2ccccc12 nan
2945586 33891 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.6 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1ccncc1)c1cc2ccccc2o1 nan
CHEMBL1423531 33891 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.6 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1ccncc1)c1cc2ccccc2o1 nan
614539 33928 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Br)cc2c1OCC2 nan
CHEMBL1423802 33928 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Br)cc2c1OCC2 nan
5928009 34248 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 9 -0.1 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CCC(C(N)=O)CC3)nc12 nan
CHEMBL1426470 34248 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 9 -0.1 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CCC(C(N)=O)CC3)nc12 nan
20957179 34344 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 9 0.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
CHEMBL1427296 34344 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 9 0.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
2376694 34349 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 8 0.5 Cn1c(N)c(C(=O)CSc2nc3ccccc3[nH]2)c(=O)n(C)c1=O nan
CHEMBL1427343 34349 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 8 0.5 Cn1c(N)c(C(=O)CSc2nc3ccccc3[nH]2)c(=O)n(C)c1=O nan
20970067 34574 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 9 1 8 2.4 COc1ccc(OC)c(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)c1 nan
CHEMBL1429318 34574 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 9 1 8 2.4 COc1ccc(OC)c(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)c1 nan
2950264 34593 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 6 2.6 O=C(CSc1ncnc2sc3c(c12)CCC3)NCC1CCCO1 nan
CHEMBL1429474 34593 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 6 2.6 O=C(CSc1ncnc2sc3c(c12)CCC3)NCC1CCCO1 nan
135436945 35091 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 2 4 5.5 Cc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c(C)c1 nan
CHEMBL1433539 35091 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 2 4 5.5 Cc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c(C)c1 nan
16030485 35192 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1435046 35192 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
1775325 35251 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 0 6 4.3 COc1ccc(CN2COc3ccc4c(oc(=O)c5ccccc54)c3C2)cc1OC nan
CHEMBL1435817 35251 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 0 6 4.3 COc1ccc(CN2COc3ccc4c(oc(=O)c5ccccc54)c3C2)cc1OC nan
135433305 35756 None 1 Human Functional pPotency = 4.9 4.9 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 3 8 1.3 CNC(=O)NC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1440872 35756 None 1 Human Functional pPotency = 4.9 4.9 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 3 8 1.3 CNC(=O)NC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
2816654 36398 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 1 6 1.9 CCOC(=O)N1CCc2c(sc3ncnc(O)c23)C1 nan
CHEMBL1446784 36398 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 1 6 1.9 CCOC(=O)N1CCc2c(sc3ncnc(O)c23)C1 nan
749058 36462 None 23 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 5 4.8 O=c1c2c(-c3cccs3)csc2[nH]c(=S)n1-c1ccccc1 nan
CHEMBL1447245 36462 None 23 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 5 4.8 O=c1c2c(-c3cccs3)csc2[nH]c(=S)n1-c1ccccc1 nan
739884 36556 None 61 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 1 1 2 3.9 O=C(O)c1sc2cc(Cl)ccc2c1Cl nan
CHEMBL1448105 36556 None 61 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 1 1 2 3.9 O=C(O)c1sc2cc(Cl)ccc2c1Cl nan
16033236 36737 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2ccccc2Cl)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1449453 36737 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2ccccc2Cl)sc2ncnc(N(C)C3CCCCC3)c12 nan
2572725 36899 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 6 2.8 Cc1cc(C(=O)OCC(=O)c2ccc(Br)s2)no1 nan
CHEMBL1450791 36899 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 6 2.8 Cc1cc(C(=O)OCC(=O)c2ccc(Br)s2)no1 nan
2787753 37119 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 4 3 8 0.6 CC(C)OC(=O)C(C)Nc1nnc(S)nc1O nan
CHEMBL1452524 37119 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 4 3 8 0.6 CC(C)OC(=O)C(C)Nc1nnc(S)nc1O nan
4984225 37598 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.8 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)Nc2cccnc2Cl)cc1 nan
CHEMBL1456558 37598 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.8 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)Nc2cccnc2Cl)cc1 nan
764734 37970 None 20 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 5 3.6 C=CCn1c(=S)[nH]c2scc(-c3ccco3)c2c1=O nan
CHEMBL1459809 37970 None 20 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 5 3.6 C=CCn1c(=S)[nH]c2scc(-c3ccco3)c2c1=O nan
2822524 38070 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 5 3.5 CCOC(=O)c1c(SC)nc2c(Cl)cccc2c1O nan
CHEMBL1460605 38070 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 5 3.5 CCOC(=O)c1c(SC)nc2c(Cl)cccc2c1O nan
2973900 38392 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 3 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3ccccc3)nc12 nan
CHEMBL1463377 38392 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 3 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3ccccc3)nc12 nan
5637963 38472 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 0 5 3.7 CCOC(=O)/C(C#N)=C/c1cc2ccccc2nc1N1CCCCC1 nan
CHEMBL1464025 38472 None 2 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 0 5 3.7 CCOC(=O)/C(C#N)=C/c1cc2ccccc2nc1N1CCCCC1 nan
1005162 38516 None 9 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.9 N#Cc1ccc(-c2ccc(F)cc2)nc1SCC(=O)Nc1sc2c(c1C#N)CCC2 nan
CHEMBL1464360 38516 None 9 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.9 N#Cc1ccc(-c2ccc(F)cc2)nc1SCC(=O)Nc1sc2c(c1C#N)CCC2 nan
2087618 38530 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 6 2.8 CCOc1cc(C=O)ccc1OCc1cc(=O)n2cc(C)ccc2n1 nan
CHEMBL1464466 38530 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 6 2.8 CCOc1cc(C=O)ccc1OCc1cc(=O)n2cc(C)ccc2n1 nan
20904553 38741 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.8 CC(NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12)c1ccccc1 nan
CHEMBL1466036 38741 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.8 CC(NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12)c1ccccc1 nan
20923124 38743 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
CHEMBL1466048 38743 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
16681736 38911 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 2 5 3.1 C1COCCO1.O=C(Nc1cccc2ccccc12)C(=O)C1C(=O)Nc2ccccc21 nan
CHEMBL1467358 38911 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 2 5 3.1 C1COCCO1.O=C(Nc1cccc2ccccc12)C(=O)C1C(=O)Nc2ccccc21 nan
2788467 38953 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 2 6 3.4 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
CHEMBL1467713 38953 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 2 6 3.4 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
4224805 38981 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 2.0 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCCCC3)c(=O)c2c1C nan
CHEMBL1468056 38981 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 2.0 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCCCC3)c(=O)c2c1C nan
22334123 39129 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1OC nan
CHEMBL1469191 39129 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1OC nan
5016620 39585 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 5 3.5 COc1ccc(-c2cc(C(=O)Nc3ccc(C#N)cc3)no2)cc1 nan
CHEMBL1473482 39585 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 5 3.5 COc1ccc(-c2cc(C(=O)Nc3ccc(C#N)cc3)no2)cc1 nan
775363 39727 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 7 0.7 Cc1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C nan
CHEMBL1475499 39727 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 7 0.7 Cc1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C nan
16009659 39787 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 7 4.1 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1476377 39787 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 7 4.1 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
5730013 39836 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 4.0 CCC(Sc1nnc2c(n1)[nH]c1ccccc12)C(=O)Nc1nnc(C(C)C)s1 nan
CHEMBL1476964 39836 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 4.0 CCC(Sc1nnc2c(n1)[nH]c1ccccc12)C(=O)Nc1nnc(C(C)C)s1 nan
1782877 39896 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 2 6 3.9 COc1ccc(-c2cc3ccc(OCC(=O)NCC4CCC(C(=O)O)CC4)cc3oc2=O)cc1 nan
CHEMBL1477517 39896 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 2 6 3.9 COc1ccc(-c2cc3ccc(OCC(=O)NCC4CCC(C(=O)O)CC4)cc3oc2=O)cc1 nan
20957466 40148 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 7 1.7 CC1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
CHEMBL1479770 40148 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 7 1.7 CC1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
5378436 40150 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 6 1.4 Cn1c(=O)[nH]c2nnc(-c3ccc(Cl)c(Cl)c3)nc2c1=O nan
CHEMBL1479779 40150 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 6 1.4 Cn1c(=O)[nH]c2nnc(-c3ccc(Cl)c(Cl)c3)nc2c1=O nan
7207545 40958 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)cc3F)nn2)s1 nan
CHEMBL1486756 40958 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)cc3F)nn2)s1 nan
974443 41178 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 7 0.5 COc1cccc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1488414 41178 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 7 0.5 COc1cccc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
250222 41217 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 1 3 2.9 O=C1c2ccccc2C(O)(c2ccccc2)N1c1ccncc1 nan
CHEMBL1488698 41217 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 1 3 2.9 O=C1c2ccccc2C(O)(c2ccccc2)N1c1ccncc1 nan
2158358 41267 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 2 0 7 1.8 CCOC(=O)N1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1489076 41267 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 2 0 7 1.8 CCOC(=O)N1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
4000951 41401 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 11 1.8 Cn1c(N)c(C(=O)CSc2nn(-c3ccc(F)cc3)c(=S)s2)c(=O)n(C)c1=O nan
CHEMBL1490219 41401 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 11 1.8 Cn1c(N)c(C(=O)CSc2nn(-c3ccc(F)cc3)c(=S)s2)c(=O)n(C)c1=O nan
5310114 41461 None 2 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 7 2.1 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)O nan
CHEMBL1490578 41461 None 2 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 7 2.1 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)O nan
135436946 41471 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 2 5 5.6 CSc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)cc1 nan
CHEMBL1490651 41471 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 2 5 5.6 CSc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)cc1 nan
2857238 41641 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 2 3 4.3 CC(Oc1ccccc1)C(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 nan
CHEMBL1491753 41641 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 2 3 4.3 CC(Oc1ccccc1)C(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 nan
3913191 41806 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 2 6 2.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc(O)nc2)c1 nan
CHEMBL1493081 41806 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 2 6 2.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc(O)nc2)c1 nan
16009715 41964 None 9 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
CHEMBL1494680 41964 None 9 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
252183 42137 None 11 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 3 3 7 -0.3 O=C1NC(=O)C(=NNc2ccc([N+](=O)[O-])cc2)C(=O)N1 nan
CHEMBL1496411 42137 None 11 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 3 3 7 -0.3 O=C1NC(=O)C(=NNc2ccc([N+](=O)[O-])cc2)C(=O)N1 nan
4023603 42621 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
4921719 42621 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
CHEMBL1500596 42621 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
2100904 43135 None 4 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 6 3.9 Cc1nn(CCc2nn[nH]n2)c2nc(-c3ccc(Br)cc3)cc(C(F)(F)F)c12 nan
CHEMBL1505221 43135 None 4 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 6 3.9 Cc1nn(CCc2nn[nH]n2)c2nc(-c3ccc(Br)cc3)cc(C(F)(F)F)c12 nan
1103129 43565 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 1 3 4.1 O=C(O)c1cccc(N2C(=O)c3cc4cccc(Br)c4cc3C2=O)c1 nan
CHEMBL1508887 43565 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 1 3 4.1 O=C(O)c1cccc(N2C(=O)c3cc4cccc(Br)c4cc3C2=O)c1 nan
15990473 43986 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.6 CCOc1ccccc1NC(=O)c1cn(C2CCCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1513016 43986 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.6 CCOc1ccccc1NC(=O)c1cn(C2CCCCC2)c(=O)c2c1c1ccccc1n2C nan
3858365 44006 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 6 5.7 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1513368 44006 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 6 5.7 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
16018934 44031 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 5.9 CCc1nnc(SCc2ccc(F)cc2Cl)c2cc3sc(C)cc3n12 nan
CHEMBL1513698 44031 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 5.9 CCc1nnc(SCc2ccc(F)cc2Cl)c2cc3sc(C)cc3n12 nan
16025722 44183 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 6 6.2 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3Cl)s1)C2 nan
CHEMBL1516031 44183 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 6 6.2 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3Cl)s1)C2 nan
5110655 44553 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 3.8 Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1519696 44553 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 3.8 Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
2161841 44900 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.5 Cc1nc(SCC(=O)N2CC(=O)Nc3ccccc32)nc(C)c1C nan
CHEMBL1522742 44900 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.5 Cc1nc(SCC(=O)N2CC(=O)Nc3ccccc32)nc(C)c1C nan
1238361 45032 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 1 5 6.5 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL1523965 45032 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 1 5 6.5 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(C(F)(F)F)c1 nan
20904542 45168 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 1.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccco3)nnc12 nan
CHEMBL1525378 45168 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 1.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccco3)nnc12 nan
2592811 45211 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 4 0 7 2.5 O=[N+]([O-])c1cc2c(c(CSc3ncccn3)c1)OCOC2 nan
CHEMBL1525704 45211 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 4 0 7 2.5 O=[N+]([O-])c1cc2c(c(CSc3ncccn3)c1)OCOC2 nan
6078768 45224 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 5 4.9 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(C)cc2)c(C)c1 nan
CHEMBL1525799 45224 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 5 4.9 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(C)cc2)c(C)c1 nan
1147569 45232 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 7 3.6 COc1cc(SC)ccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
CHEMBL1525877 45232 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 7 3.6 COc1cc(SC)ccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
4181953 45354 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 1 0 3 3.9 Cn1/c(=N\C(=O)c2ccc(F)cc2)sc2cc(Br)ccc21 nan
CHEMBL1526825 45354 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 1 0 3 3.9 Cn1/c(=N\C(=O)c2ccc(F)cc2)sc2cc(Br)ccc21 nan
5380406 45371 None 64 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 0 1 3 2.7 O=c1oc2cc(O)ccc2c2ccccc12 nan
CHEMBL1526978 45371 None 64 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 0 1 3 2.7 O=c1oc2cc(O)ccc2c2ccccc12 nan
5641185 45582 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 8 0.1 Cc1c(C(=O)NNc2cc(=O)n(C)c(=O)n2C)cccc1[N+](=O)[O-] nan
CHEMBL1528897 45582 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 8 0.1 Cc1c(C(=O)NNc2cc(=O)n(C)c(=O)n2C)cccc1[N+](=O)[O-] nan
1016791 45635 None 10 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 CC(C)c1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
CHEMBL1529358 45635 None 10 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 CC(C)c1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
7411882 45784 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)cc1 nan
CHEMBL1530681 45784 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)cc1 nan
16017598 45905 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)c1 nan
CHEMBL1531718 45905 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)c1 nan
16025817 45997 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 1 5 5.3 CCOc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1532579 45997 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 1 5 5.3 CCOc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
20939726 46077 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 0 7 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCOc2ccccc21 nan
CHEMBL1533261 46077 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 0 7 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCOc2ccccc21 nan
16033292 46227 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 6 5.4 CSc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1534658 46227 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 6 5.4 CSc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
135521540 46363 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 2 6 4.5 O=C(CCS(=O)(=O)c1ccccc1)Nc1ccc(-c2nc3ccccc3s2)c(O)c1 nan
CHEMBL1536204 46363 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 2 6 4.5 O=C(CCS(=O)(=O)c1ccccc1)Nc1ccc(-c2nc3ccccc3s2)c(O)c1 nan
2729862 46945 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 2 8 0.2 Cc1ccc(NCC(O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1541137 46945 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 2 8 0.2 Cc1ccc(NCC(O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
2487501 46992 None 23 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 2 6 1.3 Oc1nc2ccccc2n2c(S)nnc12 nan
CHEMBL1541468 46992 None 23 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 2 6 1.3 Oc1nc2ccccc2n2c(S)nnc12 nan
16194809 47337 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1nnc2ccc(-c3ccccn3)nn12)NCC1CCCO1 nan
CHEMBL1544280 47337 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1nnc2ccc(-c3ccccn3)nn12)NCC1CCCO1 nan
1866349 47457 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
661670 47457 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1406059 47457 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1545185 47457 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
15988305 48254 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 2.5 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
CHEMBL1552888 48254 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 2.5 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
1327631 48417 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CCc1ccc(OCC(=O)Nc2ccc3oc(-c4ccc(OC)cc4)nc3c2)cc1 nan
CHEMBL1555206 48417 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CCc1ccc(OCC(=O)Nc2ccc3oc(-c4ccc(OC)cc4)nc3c2)cc1 nan
16033300 48430 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 5.3 CCc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1555399 48430 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 5.3 CCc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
20970028 48510 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 5 1.7 CC(C)NS(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
CHEMBL1556192 48510 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 5 1.7 CC(C)NS(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
5202629 48728 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 7 2.4 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
CHEMBL1558116 48728 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 7 2.4 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
7411867 49028 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 0 4 4.3 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2)CC1 nan
CHEMBL1560888 49028 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 0 4 4.3 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2)CC1 nan
20923142 49214 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 1.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC(C)C nan
CHEMBL1562552 49214 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 1.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC(C)C nan
3505859 49216 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 8 2.3 CCN(CC)S(=O)(=O)c1ccc(C)c(NC(=O)Cn2cnc3cc([N+](=O)[O-])ccc3c2=O)c1 nan
CHEMBL1562557 49216 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 8 2.3 CCN(CC)S(=O)(=O)c1ccc(C)c(NC(=O)Cn2cnc3cc([N+](=O)[O-])ccc3c2=O)c1 nan
7524261 49316 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 2.6 CCS(=O)(=O)Nc1cccc(-c2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1563485 49316 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 2.6 CCS(=O)(=O)Nc1cccc(-c2ccc3nnc(-c4cccnc4)n3n2)c1 nan
5389817 49486 None 6 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 1 6 3.2 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCOC)C23C(=O)N(C)c2ccccc23)cc1 nan
CHEMBL1564945 49486 None 6 Human Functional pPotency = 4.9 4.9 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 1 6 3.2 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCOC)C23C(=O)N(C)c2ccccc23)cc1 nan
1111955 49501 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 4.1 COc1ccc(-n2nc3ccc(NC(=O)COc4ccc(C)c(C)c4)cc3n2)cc1 nan
CHEMBL1565140 49501 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 4.1 COc1ccc(-n2nc3ccc(NC(=O)COc4ccc(C)c(C)c4)cc3n2)cc1 nan
15988272 49836 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 0 9 2.0 COC(=O)c1ccc(OC)c(Cn2c(=O)n(-c3ccc(C)cc3)c(=O)c3c2cnn3C)c1 nan
CHEMBL1567650 49836 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 0 9 2.0 COC(=O)c1ccc(OC)c(Cn2c(=O)n(-c3ccc(C)cc3)c(=O)c3c2cnn3C)c1 nan
15991345 50032 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 0 5 5.1 CSc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2ccc(C)cn2)cc1 nan
CHEMBL1569335 50032 None 7 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 0 5 5.1 CSc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2ccc(C)cn2)cc1 nan
15988962 50319 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCN(CCC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1571921 50319 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCN(CCC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
2483422 50824 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 6 1.1 Cn1c(CCC(=O)OCC(=O)NCC(F)(F)F)nc(=O)c2ccccc21 nan
CHEMBL1576699 50824 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 6 1.1 Cn1c(CCC(=O)OCC(=O)NCC(F)(F)F)nc(=O)c2ccccc21 nan
5070065 51302 None 14 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 1 8 5.1 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(C)=O)s2)c1 nan
CHEMBL1580853 51302 None 14 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 1 8 5.1 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(C)=O)s2)c1 nan
4295307 51376 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1ccccc1C1C(C(=O)c2cc3ccccc3o2)=C(O)C(=O)N1c1cc(C)on1 nan
CHEMBL1581437 51376 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1ccccc1C1C(C(=O)c2cc3ccccc3o2)=C(O)C(=O)N1c1cc(C)on1 nan
4808157 51569 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 0.5 COc1ccc(OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1583111 51569 None 3 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 0.5 COc1ccc(OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
6530035 52080 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 2.6 CCN(CC)S(=O)(=O)c1ccc(C(=O)NCCN2C(=O)S/C(=C\c3cccnc3)C2=O)cc1 nan
CHEMBL1587266 52080 None 1 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 2.6 CCN(CC)S(=O)(=O)c1ccc(C(=O)NCCN2C(=O)S/C(=C\c3cccnc3)C2=O)cc1 nan
15988968 52484 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)c(OC)c1 nan
CHEMBL1591154 52484 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)c(OC)c1 nan
16024517 52501 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 5.0 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C(C)C)cc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1591352 52501 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 5.0 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C(C)C)cc3)c3nc(C)ccc3c2=O)cc1 nan
16018826 52565 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 6 4.2 CCc1cccc(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1592153 52565 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 6 4.2 CCc1cccc(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
16010502 52645 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2F)CC1 nan
CHEMBL1593224 52645 None 4 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2F)CC1 nan
1191851 53188 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.0 CCc1ccccc1NC(=O)COc1ccc2oc(-c3ccc(OC)cc3)cc(=O)c2c1 nan
CHEMBL1598484 53188 None 8 Human Functional pPotency = 4.9 4.9 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.0 CCc1ccccc1NC(=O)COc1ccc2oc(-c3ccc(OC)cc3)cc(=O)c2c1 nan
20888741 53379 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 7 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCCC2)s1 nan
CHEMBL1600180 53379 None 12 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 7 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCCC2)s1 nan
16018860 53586 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 6 4.6 Cc1ccc(NC(=O)CSc2nnc(C)n3c2cc2sccc23)c(C)c1 nan
CHEMBL1602197 53586 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 6 4.6 Cc1ccc(NC(=O)CSc2nnc(C)n3c2cc2sccc23)c(C)c1 nan
135460554 53825 None 4 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 7 2.5 CC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1604187 53825 None 4 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 7 2.5 CC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
16194880 53904 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 8 2.2 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)OC nan
CHEMBL1604935 53904 None 9 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 8 2.2 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)OC nan
2939815 54179 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2ccccc2n2c(SCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1607085 54179 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2ccccc2n2c(SCC(=O)NCC3CCCO3)nnc12 nan
16017570 54543 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 6 3.3 CN(Cc1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2cccc(Cl)c2)s1 nan
CHEMBL1610070 54543 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 6 3.3 CN(Cc1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2cccc(Cl)c2)s1 nan
7184628 54647 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccccc3)nnc12 nan
CHEMBL1611000 54647 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccccc3)nnc12 nan
20957175 54939 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 0 8 1.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)N1CCCCC1 nan
CHEMBL1613668 54939 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 0 8 1.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)N1CCCCC1 nan
11077 55052 None 27 Human Functional pPotency = 4.9 4.9 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
CHEMBL1353221 55052 None 27 Human Functional pPotency = 4.9 4.9 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
CHEMBL1616414 55052 None 27 Human Functional pPotency = 4.9 4.9 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
686692 55072 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
CHEMBL1309275 55072 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
CHEMBL1616571 55072 None 6 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
694704 55360 None 41 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1373811 55360 None 41 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1618856 55360 None 41 Human Functional pPotency = 4.9 4.9 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
3246720 55680 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
CHEMBL1445386 55680 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
CHEMBL1621717 55680 None 0 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
135439671 72225 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 2 9 0.1 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/c2c[nH]nc2-c2ccc(F)cc2)n(C)c1=O nan
CHEMBL1980641 72225 None 5 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 2 9 0.1 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/c2c[nH]nc2-c2ccc(F)cc2)n(C)c1=O nan
6187702 72798 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 6 2.6 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1ccc(N2CCOCC2)cc1 nan
CHEMBL1999641 72798 None 2 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 6 2.6 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1ccc(N2CCOCC2)cc1 nan
2058613 108424 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1cccc(OC)c1 nan
CHEMBL3198223 108424 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1cccc(OC)c1 nan
2947382 176421 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 1 5 1.8 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)C2CCCO2)c1 nan
CHEMBL459529 176421 None 8 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 1 5 1.8 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)C2CCCO2)c1 nan
3151452 202040 None 13 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 8 1.8 COCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL592554 202040 None 13 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 8 1.8 COCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3cccc(C)c3nc21 nan
3159270 204061 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 0 5 2.6 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCN(C)C)CC2 nan
CHEMBL605753 204061 None 10 Human Functional pPotency = 4.9 4.9 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 0 5 2.6 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCN(C)C)CC2 nan
9687 185441 None 21 Human Functional pPotency = 6.8 6.8 1 4
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL1522836 185441 None 21 Human Functional pPotency = 6.8 6.8 1 4
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL485980 185441 None 21 Human Functional pPotency = 6.8 6.8 1 4
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
16682183 25354 None 1 Human Functional pPotency = 5.8 5.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 2 0 5 4.6 CC(C)C(=O)N1CCC2(CC1)Oc1ccc(F)cc1C(=O)C21CC(c2ccc(Cl)cc2)=NO1 nan
CHEMBL1349353 25354 None 1 Human Functional pPotency = 5.8 5.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 2 0 5 4.6 CC(C)C(=O)N1CCC2(CC1)Oc1ccc(F)cc1C(=O)C21CC(c2ccc(Cl)cc2)=NO1 nan
123807 871 None 35 Human Functional pPotency = 4.8 4.8 -2630 7
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
374 871 None 35 Human Functional pPotency = 4.8 4.8 -2630 7
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
379 871 None 35 Human Functional pPotency = 4.8 4.8 -2630 7
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
CHEMBL284969 871 None 35 Human Functional pPotency = 4.8 4.8 -2630 7
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
2099 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
4740 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
4740.0 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
7095 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
CHEMBL628 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
DB00806 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
123683 3121 None 46 Human Functional pPotency = 4.8 4.8 -33884 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
422 3121 None 46 Human Functional pPotency = 4.8 4.8 -33884 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
CHEMBL119709 3121 None 46 Human Functional pPotency = 4.8 4.8 -33884 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
DB05511 3121 None 46 Human Functional pPotency = 4.8 4.8 -33884 5
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
2808307 10388 None 2 Human Functional pPotency = 4.8 4.8 -9 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 4 4.2 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)c1ccccc1C(=O)O nan
CHEMBL1162415 10388 None 2 Human Functional pPotency = 4.8 4.8 -9 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 4 4.2 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)c1ccccc1C(=O)O nan
16019490 11004 None 4 Human Functional pPotency = 4.8 4.8 -8 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)c1 nan
CHEMBL1173709 11004 None 4 Human Functional pPotency = 4.8 4.8 -8 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)c1 nan
2729861 20413 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 8 0.0 Cn1c(=O)c2c(ncn2CC(O)CNc2ccc(F)cc2)n(C)c1=O nan
CHEMBL1306604 20413 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 8 0.0 Cn1c(=O)c2c(ncn2CC(O)CNc2ccc(F)cc2)n(C)c1=O nan
713572 20516 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 0 2 4 3.0 CC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
CHEMBL1307433 20516 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 0 2 4 3.0 CC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
20884214 20803 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 1.4 CCC(C(=O)NCCN1CCOCC1)n1nc(C)n2c(cc3sccc32)c1=O nan
CHEMBL1309746 20803 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 1.4 CCC(C(=O)NCCN1CCOCC1)n1nc(C)n2c(cc3sccc32)c1=O nan
1831123 20856 None 5 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 3 1 7 5.2 Cc1nc2c(sc3nc(N4CCOCC4)c4c(c32)CC(C)(C)OC4)c(-c2ccccc2)c1C(=O)O nan
CHEMBL1310276 20856 None 5 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 3 1 7 5.2 Cc1nc2c(sc3nc(N4CCOCC4)c4c(c32)CC(C)(C)OC4)c(-c2ccccc2)c1C(=O)O nan
16194788 21043 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.2 O=C(CSc1nnc2ccc(-c3ccccc3)nn12)NCC1CCCO1 nan
CHEMBL1311747 21043 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.2 O=C(CSc1nnc2ccc(-c3ccccc3)nn12)NCC1CCCO1 nan
2820129 21141 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 2 4 2.2 CSc1sc(C(=O)NNC(C)=O)c2c1C=CCC2 nan
CHEMBL1312452 21141 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 2 4 2.2 CSc1sc(C(=O)NNC(C)=O)c2c1C=CCC2 nan
622563 21214 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 0 4 3.1 CN1c2ccc(C=O)c3c(C=O)ccc(c23)N(C)C1(C)C nan
CHEMBL1312974 21214 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 0 4 3.1 CN1c2ccc(C=O)c3c(C=O)ccc(c23)N(C)C1(C)C nan
4584575 21281 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 5 3.7 CC(C)N=C(S)n1cc(C(=O)c2cc(Cl)cc(Cl)c2O)cn1 nan
CHEMBL1313487 21281 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 5 3.7 CC(C)N=C(S)n1cc(C(=O)c2cc(Cl)cc(Cl)c2O)cn1 nan
16029652 21510 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 5.0 CCOc1ccc(NC(=O)c2sc3nc(-c4ccc(OC)cc4)cn3c2C)cc1 nan
CHEMBL1315982 21510 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 5.0 CCOc1ccc(NC(=O)c2sc3nc(-c4ccc(OC)cc4)cn3c2C)cc1 nan
1116235 21570 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 9 0.7 COc1cc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)cc1Cl nan
CHEMBL1316844 21570 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 9 0.7 COc1cc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)cc1Cl nan
16030395 21591 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
CHEMBL1317102 21591 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
16018828 21596 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.1 Cc1ccc(NC(=O)CSc2nncn3c2cc2sccc23)cc1F nan
CHEMBL1317182 21596 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.1 Cc1ccc(NC(=O)CSc2nncn3c2cc2sccc23)cc1F nan
16018832 21626 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1317561 21626 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
16025821 21663 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 1 5 4.9 CN(C)c1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1318005 21663 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 1 5 4.9 CN(C)c1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
1482206 21740 None 19 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 2.1 CS(=O)(=O)c1ccc(-c2cn3cc(C(=O)O)ccc3n2)cc1 nan
CHEMBL1318777 21740 None 19 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 2.1 CS(=O)(=O)c1ccc(-c2cn3cc(C(=O)O)ccc3n2)cc1 nan
1115262 21761 None 25 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 2 4 5.5 O=C(O)c1ccc(Nc2nc(-c3ccccc3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1318956 21761 None 25 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 2 4 5.5 O=C(O)c1ccc(Nc2nc(-c3ccccc3)c3cc(Br)ccc3n2)cc1 nan
16025794 21763 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.2 Cc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1318960 21763 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.2 Cc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
16021547 21777 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 6 2 8 1.8 NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(c3ncnc4c3nc3n4CCCCC3)CC2)cc1 nan
CHEMBL1319081 21777 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 6 2 8 1.8 NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(c3ncnc4c3nc3n4CCCCC3)CC2)cc1 nan
6287803 21782 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 6 4.6 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(Br)cc3)ccc2O1 nan
CHEMBL1319132 21782 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 6 4.6 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(Br)cc3)ccc2O1 nan
15988299 21805 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
CHEMBL1319322 21805 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
3152547 21991 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.2 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1F)c1ccco1 nan
CHEMBL1320921 21991 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.2 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1F)c1ccco1 nan
829953 22103 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 5 2.4 CCN(CC)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1321896 22103 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 5 2.4 CCN(CC)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
3147388 22269 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 1 4 2.9 Cc1cc(SCC(=O)NCC2CCCO2)nc2ccccc12 nan
CHEMBL1323473 22269 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 1 4 2.9 Cc1cc(SCC(=O)NCC2CCCO2)nc2ccccc12 nan
3154196 22370 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 8 -0.1 CN(CC(O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)c1ccccc1 nan
CHEMBL1324245 22370 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 8 -0.1 CN(CC(O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)c1ccccc1 nan
16019851 22431 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 11 1 9 1.9 CCOCCCNC(=O)CCc1nnc2ccc(N3CCN(c4cccc(OC)c4)CC3)nn12 nan
CHEMBL1324764 22431 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 11 1 9 1.9 CCOCCCNC(=O)CCc1nnc2ccc(N3CCN(c4cccc(OC)c4)CC3)nn12 nan
16018924 22456 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 0 5 5.2 CCc1nnc(SCc2cccc(F)c2)c2cc3sc(C)cc3n12 nan
CHEMBL1324960 22456 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 0 5 5.2 CCc1nnc(SCc2cccc(F)c2)c2cc3sc(C)cc3n12 nan
4156222 22515 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 6 2.5 O=C(c1cccc([N+](=O)[O-])c1)N1CCCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1 nan
CHEMBL1325527 22515 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 6 2.5 O=C(c1cccc([N+](=O)[O-])c1)N1CCCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1 nan
16012102 22658 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
CHEMBL1326931 22658 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
342695 22851 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 8 0.6 Cn1c([N+](=O)[O-])cnc1N1CCN(c2nncs2)C1=O nan
CHEMBL1328402 22851 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 8 0.6 Cn1c([N+](=O)[O-])cnc1N1CCN(c2nncs2)C1=O nan
5048043 22876 None 6 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1328648 22876 None 6 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
16195662 22968 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccncc4)n3n2)CC1 nan
CHEMBL1329498 22968 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccncc4)n3n2)CC1 nan
15988282 23005 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.0 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(F)cc3)nnc12 nan
CHEMBL1329775 23005 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.0 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(F)cc3)nnc12 nan
753118 23187 None 42 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1331202 23187 None 42 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1532594 23187 None 42 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
15989826 23314 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 1 6 3.2 Cc1ccc2nc(NCc3ccccc3Cl)c3nnnn3c2c1 nan
CHEMBL1332222 23314 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 1 6 3.2 Cc1ccc2nc(NCc3ccccc3Cl)c3nnnn3c2c1 nan
7120050 23911 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 3.9 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccc(F)cc1 nan
CHEMBL1336910 23911 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 3.9 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccc(F)cc1 nan
2997990 23949 None 3 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 10 -0.2 Cc1cc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(C)n1C nan
CHEMBL1337270 23949 None 3 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 10 -0.2 Cc1cc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(C)n1C nan
5827230 24028 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 9 3.4 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1338023 24028 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 9 3.4 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
4385163 24209 None 8 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 2 4 4.5 COc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1339561 24209 None 8 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 2 4 4.5 COc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
8030040 24382 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 2 5 3.2 O=C(NCCNC(=O)c1ccc(-c2ccc(Cl)c(Cl)c2)o1)c1cnccn1 nan
CHEMBL1341144 24382 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 2 5 3.2 O=C(NCCNC(=O)c1ccc(-c2ccc(Cl)c(Cl)c2)o1)c1cnccn1 nan
661441 24786 None 5 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1344527 24786 None 5 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1530959 24786 None 5 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
865623 24791 None 0 Human Functional pPotency = 4.8 4.8 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 3 0 5 3.5 CN(C)c1ccc(-c2nnc(-c3cccs3)o2)cc1 nan
CHEMBL1344555 24791 None 0 Human Functional pPotency = 4.8 4.8 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 3 0 5 3.5 CN(C)c1ccc(-c2nnc(-c3cccs3)o2)cc1 nan
2937580 24908 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 5 3.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(CC3CCCO3)C2c2ccccc2F)o1 nan
CHEMBL1345579 24908 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 5 3.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(CC3CCCO3)C2c2ccccc2F)o1 nan
1375907 25048 None 4 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 0 7 1.4 CCOC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
CHEMBL1346739 25048 None 4 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 0 7 1.4 CCOC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
5037672 25105 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 8 1.4 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cn2ccccc2n1 nan
CHEMBL1347181 25105 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 8 1.4 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cn2ccccc2n1 nan
3748480 25171 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1347701 25171 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
6463240 25193 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 9 0.6 CC(C)n1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1347878 25193 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 9 0.6 CC(C)n1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
4046369 25330 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCCC4)c3)nc2n1 nan
CHEMBL1349141 25330 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCCC4)c3)nc2n1 nan
5810234 25365 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1349428 25365 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
664152 25411 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 6 3.1 Cc1nc(SCC(=O)NCC2CCCO2)c2oc3ccccc3c2n1 nan
CHEMBL1349799 25411 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 6 3.1 Cc1nc(SCC(=O)NCC2CCCO2)c2oc3ccccc3c2n1 nan
4648816 25453 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 8 2.4 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1350189 25453 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 8 2.4 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
2081076 25484 None 13 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 1 5 3.3 O=c1c2c3c(sc2[nH]c(=S)n1Cc1ccco1)CCC3 nan
CHEMBL1350435 25484 None 13 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 1 5 3.3 O=c1c2c3c(sc2[nH]c(=S)n1Cc1ccco1)CCC3 nan
6618816 25549 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
CHEMBL1351035 25549 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
3117452 25554 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 3 1.4 Cc1c2ccccc2cc[n+]1CCCS(=O)(=O)[O-] nan
CHEMBL1351071 25554 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 3 1.4 Cc1c2ccccc2cc[n+]1CCCS(=O)(=O)[O-] nan
5809890 25678 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 1 6 3.8 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
CHEMBL1352143 25678 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 1 6 3.8 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
24794131 25690 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 0 8 2.7 CSc1ccccc1OCc1cc(C(=O)N2CCN(c3ncccn3)CC2)no1 nan
CHEMBL1352219 25690 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 0 8 2.7 CSc1ccccc1OCc1cc(C(=O)N2CCN(c3ncccn3)CC2)no1 nan
20903685 25737 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 0 8 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)CC1 nan
CHEMBL1352523 25737 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 0 8 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)CC1 nan
2322442 25776 None 3 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 5 3.3 Cc1noc(NS(=O)(=O)c2ccc(N3Cc4ccccc4C3=O)cc2)c1C nan
CHEMBL1352855 25776 None 3 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 5 3.3 Cc1noc(NS(=O)(=O)c2ccc(N3Cc4ccccc4C3=O)cc2)c1C nan
135490313 25924 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -0.6 Cc1cc(O)nc(SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)n1 nan
CHEMBL1353870 25924 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -0.6 Cc1cc(O)nc(SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)n1 nan
20923143 26036 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 6 1.6 CCCNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1354972 26036 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 6 1.6 CCCNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
1116268 26050 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 9 -0.1 COC(=O)c1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1355136 26050 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 9 -0.1 COC(=O)c1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
1003440 26166 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 2 5 5.9 Nc1c(C(=O)Nc2ccc(C(F)(F)F)cc2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1356669 26166 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 2 5 5.9 Nc1c(C(=O)Nc2ccc(C(F)(F)F)cc2)sc2nc(-c3cccs3)ccc12 nan
16024861 26246 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 4 3.0 CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1357771 26246 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 4 3.0 CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
25162722 26317 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 9 1.4 CCN(CC)c1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nncn1C nan
CHEMBL1358718 26317 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 9 1.4 CCN(CC)c1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nncn1C nan
4312795 26478 None 18 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 4 2.2 CC(Sc1cnc2ccccc2n1)C(=O)O nan
CHEMBL1360045 26478 None 18 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 4 2.2 CC(Sc1cnc2ccccc2n1)C(=O)O nan
3704657 26490 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 6 3.2 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2ncccn2)cc1 nan
CHEMBL1360163 26490 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 6 3.2 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2ncccn2)cc1 nan
24000844 26506 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.9 Cn1c2ccccc2c2nnc(SCC(=O)Nc3cccc(C(=O)O)c3)nc21 nan
CHEMBL1360279 26506 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.9 Cn1c2ccccc2c2nnc(SCC(=O)Nc3cccc(C(=O)O)c3)nc21 nan
791500 26528 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 5 3.4 CCOC(=O)c1c(C)nc(S)c(C#N)c1-c1ccccc1 nan
CHEMBL1360458 26528 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 5 3.4 CCOC(=O)c1c(C)nc(S)c(C#N)c1-c1ccccc1 nan
3178481 26707 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1362095 26707 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
5309057 26788 None 1 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 5 3.7 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccn2)CC1 nan
CHEMBL1362711 26788 None 1 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 5 3.7 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccn2)CC1 nan
16022478 26809 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 9 4.3 COc1cccc(NC(=O)c2ccc3c(=O)n4nc(Nc5ccccc5OC)sc4nc3c2)c1 nan
CHEMBL1362937 26809 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 9 4.3 COc1cccc(NC(=O)c2ccc3c(=O)n4nc(Nc5ccccc5OC)sc4nc3c2)c1 nan
20917857 27101 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.4 Cc1ccc(CNS(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)o1 nan
CHEMBL1365432 27101 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.4 Cc1ccc(CNS(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)o1 nan
2999882 27279 None 20 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 7 1 5 2.9 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1ccccc1 nan
CHEMBL1367025 27279 None 20 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 7 1 5 2.9 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1ccccc1 nan
1914729 27367 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 11 1 3 4.7 CC(=O)c1ccc(CCCCCCCCCC(=O)O)s1 nan
CHEMBL1367732 27367 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 11 1 3 4.7 CC(=O)c1ccc(CCCCCCCCCC(=O)O)s1 nan
3820161 27418 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccccc2F)o1 nan
CHEMBL1368082 27418 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccccc2F)o1 nan
135419062 27465 None 3 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 7 4.5 N#Cc1c(O)nc(SCC(=O)c2ccc(Br)cc2)nc1-c1cccs1 nan
CHEMBL1368444 27465 None 3 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 7 4.5 N#Cc1c(O)nc(SCC(=O)c2ccc(Br)cc2)nc1-c1cccs1 nan
3154099 27583 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 4.1 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1369329 27583 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 4.1 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
2443232 27819 None 3 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 1 5 6.4 O=C(COC(=O)c1cc(-c2ccccc2Cl)nc2ccccc12)Nc1ncc(C(F)(F)F)cc1Cl nan
CHEMBL1370986 27819 None 3 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 1 5 6.4 O=C(COC(=O)c1cc(-c2ccccc2Cl)nc2ccccc12)Nc1ncc(C(F)(F)F)cc1Cl nan
22548207 27851 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 0.8 CCOC(=O)CNC(=O)Cn1cnc2c(oc3ccccc32)c1=O nan
CHEMBL1371227 27851 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 0.8 CCOC(=O)CNC(=O)Cn1cnc2c(oc3ccccc32)c1=O nan
663879 28279 None 11 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 9 1 7 4.2 Cc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2ccc(OC(C)C)cc2)o1 nan
CHEMBL1374204 28279 None 11 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 9 1 7 4.2 Cc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2ccc(OC(C)C)cc2)o1 nan
20917681 28284 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 2.0 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)s1 nan
CHEMBL1374225 28284 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 2.0 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)s1 nan
4855374 28559 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 0 10 -0.3 CN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1(C#N)CCCCC1 nan
CHEMBL1376372 28559 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 0 10 -0.3 CN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1(C#N)CCCCC1 nan
20917816 28996 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 0 5 2.4 CC1CCN(S(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)CC1 nan
CHEMBL1380363 28996 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 0 5 2.4 CC1CCN(S(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)CC1 nan
661999 29081 None 10 Human Functional pPotency = 4.8 4.8 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
CHEMBL1380975 29081 None 10 Human Functional pPotency = 4.8 4.8 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
4342649 29194 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
5027943 29194 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
CHEMBL1381980 29194 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
135431552 29262 None 7 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 6 4.7 N#Cc1c(O)nc(SCc2ccc(Cl)cc2)nc1-c1cccs1 nan
CHEMBL1382616 29262 None 7 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 6 4.7 N#Cc1c(O)nc(SCc2ccc(Cl)cc2)nc1-c1cccs1 nan
921583 29655 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 1 1 3 4.3 Sc1nc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1386089 29655 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 1 1 3 4.3 Sc1nc(-c2ccccc2)nc2ccc(Br)cc12 nan
5428525 29976 None 20 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 1 5 1.8 COC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
CHEMBL1388510 29976 None 20 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 1 5 1.8 COC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
5824610 30024 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 7 1 5 3.1 CN(C)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1388949 30024 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 7 1 5 3.1 CN(C)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
16194879 30372 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c(OC)c1 nan
CHEMBL1391905 30372 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c(OC)c1 nan
1256976 30433 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 2 5 3.6 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3cccnc3)nc3ccc(Br)cc23)cc1 nan
CHEMBL1392432 30433 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 2 5 3.6 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3cccnc3)nc3ccc(Br)cc23)cc1 nan
7222624 30728 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)c(F)c3)nn2)s1 nan
CHEMBL1395178 30728 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)c(F)c3)nn2)s1 nan
16018363 30752 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 6 5.5 COc1ccc(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(OC)cc4)cn23)cc1 nan
CHEMBL1395439 30752 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 6 5.5 COc1ccc(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(OC)cc4)cn23)cc1 nan
15990211 30903 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 6 3.1 Fc1ccc(CNc2nc3ccc(Cl)cc3n3nnnc23)cc1 nan
CHEMBL1397707 30903 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 6 3.1 Fc1ccc(CNc2nc3ccc(Cl)cc3n3nnnc23)cc1 nan
7151328 30964 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 5 3.1 CCS(=O)(=O)Nc1ccc(-c2cn3c(C)csc3n2)cc1 nan
CHEMBL1398475 30964 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 5 3.1 CCS(=O)(=O)Nc1ccc(-c2cn3c(C)csc3n2)cc1 nan
20939725 31066 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 0 7 2.9 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)Oc2ccccc21 nan
CHEMBL1399426 31066 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 0 7 2.9 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)Oc2ccccc21 nan
16452548 31317 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)c1 nan
CHEMBL1401713 31317 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)c1 nan
3709623 31427 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)o1 nan
CHEMBL1402642 31427 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)o1 nan
5212778 31455 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
661982 31455 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
CHEMBL1402874 31455 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
3152754 31538 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 5 4.2 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccs1)c1ccco1 nan
CHEMBL1403767 31538 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 5 4.2 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccs1)c1ccco1 nan
2816622 31615 None 5 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 4.8 COc1ccc(-n2c(=S)[nH]c3sc(-c4ccccc4)cc3c2=O)c(OC)c1 nan
CHEMBL1404356 31615 None 5 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 4.8 COc1ccc(-n2c(=S)[nH]c3sc(-c4ccccc4)cc3c2=O)c(OC)c1 nan
7245568 31741 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 2.2 COc1ccc(NC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1405733 31741 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 2.2 COc1ccc(NC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
4184357 31759 None 5 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 6 1 9 4.3 O=C(O)c1ccc(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)cc1 nan
CHEMBL1405932 31759 None 5 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 6 1 9 4.3 O=C(O)c1ccc(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)cc1 nan
757946 31995 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 2 4.7 Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(=O)O nan
CHEMBL1407788 31995 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 2 4.7 Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(=O)O nan
3160259 32068 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 7 2.2 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCC(C)O nan
CHEMBL1408356 32068 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 7 2.2 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCC(C)O nan
1071246 32141 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 8 0.6 CCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1408937 32141 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 8 0.6 CCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
744304 32176 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 2 4 2.4 COc1ccc2[nH]c3c(S)ncnc3c2c1 nan
CHEMBL1409203 32176 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 2 4 2.4 COc1ccc2[nH]c3c(S)ncnc3c2c1 nan
3240452 32178 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 0.4 O=C(Cn1cnc2c(nnn2-c2ccc(F)cc2)c1=O)NCC1CCCO1 nan
CHEMBL1409223 32178 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 0.4 O=C(Cn1cnc2c(nnn2-c2ccc(F)cc2)c1=O)NCC1CCCO1 nan
15989908 32284 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1410062 32284 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
20923121 32324 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 2.0 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccco1 nan
CHEMBL1410345 32324 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 2.0 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccco1 nan
3998353 32517 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 8 1.0 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)nc2n1 nan
CHEMBL1412011 32517 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 8 1.0 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)nc2n1 nan
16034646 32610 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 3.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(Cl)cc3)nnc12 nan
CHEMBL1412706 32610 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 3.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(Cl)cc3)nnc12 nan
1145396 32708 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
5026856 32708 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
CHEMBL1413474 32708 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
652152 32851 None 10 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 2 1 3 2.7 COc1ccc2c(Cl)c(C(N)=O)sc2c1 nan
CHEMBL1414671 32851 None 10 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 2 1 3 2.7 COc1ccc2c(Cl)c(C(N)=O)sc2c1 nan
1004109 32969 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 2 4 5.4 Cc1ccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1F nan
CHEMBL1415733 32969 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 2 4 5.4 Cc1ccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1F nan
22334931 33029 None 22 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 4 3.5 O=C(O)CSc1nc2ccccc2nc1Cc1ccccc1F nan
CHEMBL1416271 33029 None 22 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 4 3.5 O=C(O)CSc1nc2ccccc2nc1Cc1ccccc1F nan
3953394 33134 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 8 1.5 O=C(CSc1nnc2ccccn12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1417177 33134 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 8 1.5 O=C(CSc1nnc2ccccn12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
24687828 33149 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 0 11 -0.1 COc1ccc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1 nan
CHEMBL1417257 33149 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 0 11 -0.1 COc1ccc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1 nan
7184635 33402 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1cccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1419486 33402 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1cccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
4796292 33447 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 6 1.1 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cnccn2)c1 nan
CHEMBL1419907 33447 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 6 1.1 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cnccn2)c1 nan
744542 33470 None 24 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 3 3.4 Cc1cc(SCCC(=O)O)nc2c(C)cccc12 nan
CHEMBL1420044 33470 None 24 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 3 3.4 Cc1cc(SCCC(=O)O)nc2c(C)cccc12 nan
3789487 33540 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 3.0 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(F)cc1)c1ccco1 nan
CHEMBL1420588 33540 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 3.0 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(F)cc1)c1ccco1 nan
1473006 33594 None 12 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 0 2 4.1 COc1cc2cc(Br)cc(Br)c2nc1C nan
CHEMBL1421084 33594 None 12 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 0 2 4.1 COc1cc2cc(Br)cc(Br)c2nc1C nan
22421602 33649 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 9 2 8 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1 nan
CHEMBL1421499 33649 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 9 2 8 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1 nan
20957484 33656 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 9 1.3 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
CHEMBL1421579 33656 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 9 1.3 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
7190683 33671 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1421703 33671 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
7190642 33814 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1422914 33814 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
741274 34045 None 7 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 0 7 0.6 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCC3 nan
CHEMBL1424800 34045 None 7 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 0 7 0.6 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCC3 nan
3816425 34131 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1425600 34131 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
7299201 34139 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.6 Cc1cccc(C)c1Nc1c(-c2ccc(N3CCOCC3)cc2)nc2cnccn12 nan
CHEMBL1425693 34139 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.6 Cc1cccc(C)c1Nc1c(-c2ccc(N3CCOCC3)cc2)nc2cnccn12 nan
5739077 34315 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 8 2.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1427088 34315 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 8 2.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3830309 34448 None 14 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 6 4.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1cc2ccccc2o1 nan
CHEMBL1428271 34448 None 14 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 6 4.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1cc2ccccc2o1 nan
20903609 34699 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 9 1 10 3.0 COc1cc(NC(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)cc(OC)c1 nan
CHEMBL1430241 34699 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 9 1 10 3.0 COc1cc(NC(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)cc(OC)c1 nan
990446 34726 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 9 2.1 COc1cccc(-n2nc3c(-n4ncc(C#N)c4N)nnc(C)c3c2C)c1 nan
CHEMBL1430459 34726 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 9 2.1 COc1cccc(-n2nc3c(-n4ncc(C#N)c4N)nnc(C)c3c2C)c1 nan
2809114 34875 None 2 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 4 4.7 CC(=O)c1sc(-c2ccccc2)cc1NS(=O)(=O)c1ccc(C)cc1 nan
CHEMBL1431741 34875 None 2 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 4 4.7 CC(=O)c1sc(-c2ccccc2)cc1NS(=O)(=O)c1ccc(C)cc1 nan
4968705 35027 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 0 10 -0.5 CN(C)S(=O)(=O)c1ccc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1433054 35027 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 0 10 -0.5 CN(C)S(=O)(=O)c1ccc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
16019549 35121 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 3 0 9 2.8 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(N1CCOCC1)c1sccc12 nan
CHEMBL1433993 35121 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 3 0 9 2.8 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(N1CCOCC1)c1sccc12 nan
20885693 35229 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 1 6 2.0 Cc1nn(CCCC(=O)NCCc2ccc(Cl)cc2)c(=O)c2nccn12 nan
CHEMBL1435443 35229 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 1 6 2.0 Cc1nn(CCCC(=O)NCCc2ccc(Cl)cc2)c(=O)c2nccn12 nan
4380857 35235 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1c(CN(C)C(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cnn1C nan
CHEMBL1435516 35235 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1c(CN(C)C(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cnn1C nan
5066674 35247 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 2.7 COC(=O)c1cc(NS(=O)(=O)c2cc(Br)cc3c2N(C(C)=O)CC3)cc(C(=O)OC)c1 nan
CHEMBL1435676 35247 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 2.7 COC(=O)c1cc(NS(=O)(=O)c2cc(Br)cc3c2N(C(C)=O)CC3)cc(C(=O)OC)c1 nan
3993922 35313 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 7 1.2 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1436555 35313 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 7 1.2 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2ccsc2n1 nan
16018682 35330 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.1 CCc1ccccc1NC(=O)CSc1nncn2c1cc1oc(C)cc12 nan
CHEMBL1436824 35330 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.1 CCc1ccccc1NC(=O)CSc1nncn2c1cc1oc(C)cc12 nan
16026770 35351 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 7 1.7 Cc1csc2nc(COC(=O)CNC(=O)c3ccc(F)cc3)cc(=O)n12 nan
CHEMBL1437080 35351 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 7 1.7 Cc1csc2nc(COC(=O)CNC(=O)c3ccc(F)cc3)cc(=O)n12 nan
90660425 35476 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 5 5.1 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccccc2F)cc1C nan
CHEMBL1438291 35476 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 5 5.1 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccccc2F)cc1C nan
663438 35645 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 6 1.4 O=S(=O)(c1cccc(-c2cn3cccnc3n2)c1)N1CCOCC1 nan
CHEMBL1439795 35645 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 6 1.4 O=S(=O)(c1cccc(-c2cn3cccnc3n2)c1)N1CCOCC1 nan
135544645 35654 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 7 3.7 N#Cc1c(O)nc(SCC(=O)Nc2cccc(Cl)c2)nc1-c1ccco1 nan
CHEMBL1439904 35654 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 7 3.7 N#Cc1c(O)nc(SCC(=O)Nc2cccc(Cl)c2)nc1-c1ccco1 nan
3363660 35794 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
4976974 35794 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
CHEMBL1441169 35794 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
2854626 35802 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CC(=O)C1=C(C)NC(SCC(=O)c2ccc(Cl)cc2)=C(C#N)C1CC(C)C nan
CHEMBL1441242 35802 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CC(=O)C1=C(C)NC(SCC(=O)c2ccc(Cl)cc2)=C(C#N)C1CC(C)C nan
20957185 35957 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 8 1.9 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccc(F)cc1 nan
CHEMBL1442625 35957 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 8 1.9 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccc(F)cc1 nan
812443 36152 None 33 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 2 1 4 3.2 C=CCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1444467 36152 None 33 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 2 1 4 3.2 C=CCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
20923160 36154 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccccc1CNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1444486 36154 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccccc1CNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
16745544 36532 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 1 5 2.5 COc1ccc(C2=CC3=C(Br)C(=O)C(C)(O)C(=O)C3=CO2)cc1 nan
CHEMBL1447877 36532 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 1 5 2.5 COc1ccc(C2=CC3=C(Br)C(=O)C(C)(O)C(=O)C3=CO2)cc1 nan
2376086 36596 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 5 2.6 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1448425 36596 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 5 2.6 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
16745680 36746 None 0 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 0 7 5.7 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1CC(C)C nan
CHEMBL1449527 36746 None 0 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 0 7 5.7 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1CC(C)C nan
16018684 36747 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 4.4 Cc1cc(C)c(NC(=O)CSc2nncn3c2cc2oc(C)cc23)c(C)c1 nan
CHEMBL1449543 36747 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 4.4 Cc1cc(C)c(NC(=O)CSc2nncn3c2cc2oc(C)cc23)c(C)c1 nan
1094076 36760 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.0 CC(=O)c1ccc(Nc2nc(=O)c3cccnc3s2)cc1 nan
CHEMBL1449615 36760 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.0 CC(=O)c1ccc(Nc2nc(=O)c3cccnc3s2)cc1 nan
3514089 36905 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1450861 36905 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
6619005 37124 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 5 1 7 4.4 Cc1c(N2C(=O)C(O)=C(C(=O)c3ccc(Br)cc3)C2c2cccnc2)c(=O)n(-c2ccccc2)n1C nan
CHEMBL1452549 37124 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 5 1 7 4.4 Cc1c(N2C(=O)C(O)=C(C(=O)c3ccc(Br)cc3)C2c2cccnc2)c(=O)n(-c2ccccc2)n1C nan
16194575 37301 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)s1 nan
CHEMBL1453968 37301 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)s1 nan
3178522 37366 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 0 9 0.2 CCCCn1c(SCC(=O)N2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1454485 37366 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 0 9 0.2 CCCCn1c(SCC(=O)N2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
2613266 37438 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 0 8 2.8 O=[N+]([O-])c1cc2c(c(CSc3nnc4ccccn34)c1)OCOC2 nan
CHEMBL1455089 37438 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 0 8 2.8 O=[N+]([O-])c1cc2c(c(CSc3nnc4ccccn34)c1)OCOC2 nan
1084466 37550 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 6 2.5 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
CHEMBL1456125 37550 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 6 2.5 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
20885676 37602 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 6 1.6 Cc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
CHEMBL1456629 37602 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 6 1.6 Cc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
3715206 37611 None 17 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 5 3.9 CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1456701 37611 None 17 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 5 3.9 CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
3252203 37764 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.2 O=C(CSc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
CHEMBL1457998 37764 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.2 O=C(CSc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
2939635 37867 None 32 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 247 3 1 3 3.1 Cc1cc(SC(C)C(=O)O)nc2ccccc12 nan
CHEMBL1458912 37867 None 32 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 247 3 1 3 3.1 Cc1cc(SC(C)C(=O)O)nc2ccccc12 nan
1442575 38107 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 6 1 4 3.7 CCCc1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1460883 38107 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 6 1 4 3.7 CCCc1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
4412828 38206 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 9 1 7 2.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)COc2ccc(C#N)cc2)c1 nan
CHEMBL1461851 38206 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 9 1 7 2.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)COc2ccc(C#N)cc2)c1 nan
1838049 38271 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 0.4 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1462354 38271 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 0.4 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
15945416 39015 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 3.5 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1468328 39015 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 3.5 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
4905842 39034 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 9 4.4 CSc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(SC)s2)cc1 nan
CHEMBL1468444 39034 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 9 4.4 CSc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(SC)s2)cc1 nan
6498441 39144 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 2.7 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NC1CCCC1 nan
CHEMBL1469364 39144 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 2.7 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NC1CCCC1 nan
4356276 39247 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 8 4.1 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1470300 39247 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 8 4.1 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
3776625 39302 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Br)c2)no1 nan
CHEMBL1470725 39302 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Br)c2)no1 nan
3186626 39323 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
CHEMBL1470851 39323 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
7256722 39648 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 2.4 Cc1ccc2nc(SCC(=O)Nc3ccc(F)cc3F)nc(=O)n2c1 nan
CHEMBL1474450 39648 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 2.4 Cc1ccc2nc(SCC(=O)Nc3ccc(F)cc3F)nc(=O)n2c1 nan
15990395 39797 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1cccc(NC(=O)c2nc3ccccc3n(C)c2=O)c1 nan
CHEMBL1476510 39797 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1cccc(NC(=O)c2nc3ccccc3n(C)c2=O)c1 nan
1506838 39842 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 4 3.1 Cc1cc(CNC(=O)COc2ccc(C#N)cc2)c2ccccc2n1 nan
CHEMBL1477044 39842 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 4 3.1 Cc1cc(CNC(=O)COc2ccc(C#N)cc2)c2ccccc2n1 nan
1471774 39885 None 20 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 3.0 CSc1cc(-c2ccccc2)nc(O)c1C#N nan
CHEMBL1477426 39885 None 20 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 3.0 CSc1cc(-c2ccccc2)nc(O)c1C#N nan
20970002 39895 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1 nan
CHEMBL1477514 39895 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1 nan
2931382 40189 None 11 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 2 5 2.1 COC(=O)c1sccc1NC(=O)C1CC=CCC1C(=O)O nan
CHEMBL1480089 40189 None 11 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 2 5 2.1 COC(=O)c1sccc1NC(=O)C1CC=CCC1C(=O)O nan
7120051 40196 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1480178 40196 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
16018856 40216 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 0 8 5.5 COc1ccc(-c2nc(CSc3nnc(C)n4c3cc3sccc34)c(C)o2)cc1 nan
CHEMBL1480328 40216 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 0 8 5.5 COc1ccc(-c2nc(CSc3nnc(C)n4c3cc3sccc34)c(C)o2)cc1 nan
3451317 40229 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 7 0.8 CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2nncn2C)c1 nan
CHEMBL1480436 40229 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 7 0.8 CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2nncn2C)c1 nan
3535142 40351 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 9 1 9 3.4 O=C(O)CCCCCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
CHEMBL1481365 40351 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 9 1 9 3.4 O=C(O)CCCCCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
3574141 40402 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 0 6 2.1 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(C(=O)OCC(=O)N2CCCC2)c1 nan
CHEMBL1481920 40402 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 0 6 2.1 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(C(=O)OCC(=O)N2CCCC2)c1 nan
5736472 40694 None 6 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 6 1 7 2.5 O=c1c2ccccc2nc(/C=C/c2ccc([N+](=O)[O-])o2)n1CCCO nan
CHEMBL1484332 40694 None 6 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 6 1 7 2.5 O=c1c2ccccc2nc(/C=C/c2ccc([N+](=O)[O-])o2)n1CCCO nan
5304429 40723 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 1 4 2.4 CC(=O)Nc1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1484671 40723 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 1 4 2.4 CC(=O)Nc1cccc(-c2cn3cccnc3n2)c1 nan
16012070 40759 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 7 2.9 Cc1cc(=O)n2nc(N3CCC(C(=O)Nc4c(C)cccc4C)CC3)sc2n1 nan
CHEMBL1484919 40759 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 7 2.9 Cc1cc(=O)n2nc(N3CCC(C(=O)Nc4c(C)cccc4C)CC3)sc2n1 nan
4399091 40761 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1ccccc1C1C(C(=O)c2ccc(C)o2)=C(O)C(=O)N1c1cc(C)on1 nan
CHEMBL1484932 40761 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1ccccc1C1C(C(=O)c2ccc(C)o2)=C(O)C(=O)N1c1cc(C)on1 nan
1387364 40816 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1485560 40816 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1576237 40816 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
6622721 41087 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 5 3.6 CNc1nc2c(-c3ccc(Cl)cc3)nnn2c2ccccc12 nan
CHEMBL1487831 41087 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 5 3.6 CNc1nc2c(-c3ccc(Cl)cc3)nnn2c2ccccc12 nan
1002526 41128 None 9 Human Functional pPotency = 4.8 4.8 -2 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 4 4.1 O=C(O)c1cc(-c2ccc3c(c2)OCO3)nc2ccc(Br)cc12 nan
CHEMBL1488092 41128 None 9 Human Functional pPotency = 4.8 4.8 -2 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 4 4.1 O=C(O)c1cc(-c2ccc3c(c2)OCO3)nc2ccc(Br)cc12 nan
7190684 41186 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1488468 41186 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
5881431 41285 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 1 7 4.2 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1489225 41285 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 1 7 4.2 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
2032322 41400 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 7 3.5 CCN(CC)CCCNc1nc(SC)nc2sc3c(c12)CCN(C)C3 nan
CHEMBL1490215 41400 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 7 3.5 CCN(CC)CCCNc1nc(SC)nc2sc3c(c12)CCN(C)C3 nan
755499 41507 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 7 1.0 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
CHEMBL1490891 41507 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 7 1.0 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
1283516 41700 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 7 0.9 O=c1[nH]n2cc(-n3cc([N+](=O)[O-])cn3)cnc2c1Br nan
CHEMBL1492212 41700 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 7 0.9 O=c1[nH]n2cc(-n3cc([N+](=O)[O-])cn3)cnc2c1Br nan
774862 41768 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 0 4 3.1 Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2ccccc21 nan
CHEMBL1492732 41768 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 0 4 3.1 Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2ccccc21 nan
3279901 41864 None 6 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 4 3.0 CC(=O)NC(CSc1cc(C)nc2ccc(Br)cc12)C(=O)O nan
CHEMBL1493652 41864 None 6 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 4 3.0 CC(=O)NC(CSc1cc(C)nc2ccc(Br)cc12)C(=O)O nan
4795978 41867 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 3.8 CN(C)S(=O)(=O)c1cccc(COc2ncnc3c(Cl)cc(Cl)cc23)c1 nan
CHEMBL1493688 41867 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 3.8 CN(C)S(=O)(=O)c1cccc(COc2ncnc3c(Cl)cc(Cl)cc23)c1 nan
15988336 41948 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1cccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1494501 41948 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1cccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
664285 41965 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 3 0 5 3.1 CC(=O)CSc1ncnc2c1oc1ccccc12 nan
CHEMBL1494683 41965 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 3 0 5 3.1 CC(=O)CSc1ncnc2c1oc1ccccc12 nan
748270 42007 None 34 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 0 4 2.2 Cc1nnc2c3ccccc3c(Cl)nn12 nan
CHEMBL1495086 42007 None 34 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 0 4 2.2 Cc1nnc2c3ccccc3c(Cl)nn12 nan
3186635 42117 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 0 9 -0.8 CCN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
CHEMBL1496152 42117 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 0 9 -0.8 CCN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
2561752 42353 None 15 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 3.2 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCS3 nan
CHEMBL1498284 42353 None 15 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 3.2 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCS3 nan
21552 42397 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 7 0.1 Cn1c(=O)c2c(nc(Cc3ccc(N)cc3)n2C)n(C)c1=O nan
CHEMBL1498782 42397 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 7 0.1 Cn1c(=O)c2c(nc(Cc3ccc(N)cc3)n2C)n(C)c1=O nan
7677140 42450 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 5 2.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1cccnc1 nan
CHEMBL1499143 42450 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 5 2.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1cccnc1 nan
2816379 42614 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 2.1 CCOC(=O)c1nnn2c1nc(SCC(C)=O)c1ccccc12 nan
CHEMBL1500551 42614 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 2.1 CCOC(=O)c1nnn2c1nc(SCC(C)=O)c1ccccc12 nan
18554434 42651 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 8 1.8 O=C(CSc1ncnc2c1nnn2Cc1ccccc1F)NCC1CCCO1 nan
CHEMBL1500823 42651 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 8 1.8 O=C(CSc1ncnc2c1nnn2Cc1ccccc1F)NCC1CCCO1 nan
5077853 42735 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 1 8 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1 nan
CHEMBL1501692 42735 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 1 8 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1 nan
7120056 42740 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1501734 42740 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
3884053 42896 None 11 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
661074 42896 None 11 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
CHEMBL1503060 42896 None 11 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
20957430 42933 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 3.2 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(NCc4ccc5c(c4)OCO5)nn23)c1 nan
CHEMBL1503367 42933 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 3.2 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(NCc4ccc5c(c4)OCO5)nn23)c1 nan
16452701 43039 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)n1 nan
CHEMBL1504372 43039 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)n1 nan
3457991 43169 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 5 1 8 3.2 Cc1ccc(F)cc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
CHEMBL1505540 43169 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 5 1 8 3.2 Cc1ccc(F)cc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
5198374 43183 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 7 2.4 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1505625 43183 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 7 2.4 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
986582 43285 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 3.2 CCc1ccc2oc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)c(C)c2c1 nan
CHEMBL1506399 43285 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 3.2 CCc1ccc2oc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)c(C)c2c1 nan
1811810 43318 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 2 3.5 C=CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
CHEMBL1506727 43318 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 2 3.5 C=CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
135528107 43842 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 5 3.2 CCN(CC(=O)NC(C)C)Cc1nc(O)c2cc(Br)cc(Br)c2n1 nan
CHEMBL1511291 43842 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 5 3.2 CCN(CC(=O)NC(C)C)Cc1nc(O)c2cc(Br)cc(Br)c2n1 nan
16496658 43960 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.1 CC1CCCN(C(=O)COC(=O)CNC(=O)c2sc3ccccc3c2Cl)C1 nan
CHEMBL1512634 43960 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.1 CC1CCCN(C(=O)COC(=O)CNC(=O)c2sc3ccccc3c2Cl)C1 nan
15988304 44038 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 0 8 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccccc4)CC3)nnc12 nan
CHEMBL1513808 44038 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 0 8 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccccc4)CC3)nnc12 nan
16026221 44154 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 1.2 CCOC(=O)C1CCN(C(=O)Cn2c(=O)cc(C)c3c(C)nn(C)c32)CC1 nan
CHEMBL1515615 44154 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 1.2 CCOC(=O)C1CCN(C(=O)Cn2c(=O)cc(C)c3c(C)nn(C)c32)CC1 nan
662069 44307 None 6 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 1.8 COC(=O)c1cc(Br)c(=O)n(-c2nccs2)c1 nan
CHEMBL1517409 44307 None 6 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 1.8 COC(=O)c1cc(Br)c(=O)n(-c2nccs2)c1 nan
3489758 44365 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 2 9 0.9 Cn1c(=O)c2ncn(CC(=O)N=Nc3c(O)[nH]c4ccccc34)c2n(C)c1=O nan
CHEMBL1518029 44365 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 2 9 0.9 Cn1c(=O)c2ncn(CC(=O)N=Nc3c(O)[nH]c4ccccc34)c2n(C)c1=O nan
16018686 44528 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 6 4.3 Cc1cc2c(cc3c(SCC(=O)Nc4ccc(Cl)cc4F)nncn32)o1 nan
CHEMBL1519470 44528 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 6 4.3 Cc1cc2c(cc3c(SCC(=O)Nc4ccc(Cl)cc4F)nncn32)o1 nan
20957225 44546 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 9 1.7 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)nc1 nan
CHEMBL1519640 44546 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 9 1.7 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)nc1 nan
2991435 44564 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 6 2.8 COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(Br)o2)c1 nan
CHEMBL1519787 44564 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 6 2.8 COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(Br)o2)c1 nan
5959865 44679 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 6 4.0 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(F)cc3)ccc2O1 nan
CHEMBL1520789 44679 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 6 4.0 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(F)cc3)ccc2O1 nan
4197564 44845 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 11 1 8 3.9 COc1cc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
CHEMBL1522190 44845 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 11 1 8 3.9 COc1cc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
5064245 44863 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 5 1 5 1.3 O=C(COc1ncnc2ccccc12)NCC1CCCO1 nan
CHEMBL1522316 44863 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 5 1 5 1.3 O=C(COc1ncnc2ccccc12)NCC1CCCO1 nan
3317909 44866 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
3536112 44866 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
CHEMBL1522365 44866 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
20957467 44941 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 9 1 8 1.8 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4)CC3)n2n1 nan
CHEMBL1523099 44941 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 9 1 8 1.8 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4)CC3)n2n1 nan
3242118 44954 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 1 5 2.6 Cc1nn(C(C)C(=O)O)c(=O)c2c1sc1ccccc12 nan
CHEMBL1523214 44954 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 1 5 2.6 Cc1nn(C(C)C(=O)O)c(=O)c2c1sc1ccccc12 nan
3178468 45012 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 8 0.6 CCn1c(SCC(=O)N2CCCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1523743 45012 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 8 0.6 CCn1c(SCC(=O)N2CCCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
774385 45235 None 42 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 192 1 1 4 2.3 Cc1ccccc1-c1nnc(S)o1 nan
CHEMBL1525902 45235 None 42 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 192 1 1 4 2.3 Cc1ccccc1-c1nnc(S)o1 nan
6156848 45248 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 6 3.9 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccccc3)ccc2O1 nan
CHEMBL1525999 45248 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 6 3.9 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccccc3)ccc2O1 nan
20923115 45508 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 0 6 3.1 CCN(c1ccccc1)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1528270 45508 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 0 6 3.1 CCN(c1ccccc1)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
1173803 45618 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 0 9 0.3 CCCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1529195 45618 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 0 9 0.3 CCCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
1150969 45619 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 2 6 3.2 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
CHEMBL1529199 45619 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 2 6 3.2 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
20957502 45686 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1cccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)c1 nan
CHEMBL1529803 45686 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1cccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)c1 nan
3146230 45871 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 6 2.7 Cc1sc2ncnc(SCC(=O)NCC3CCCO3)c2c1C nan
CHEMBL1531505 45871 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 6 2.7 Cc1sc2ncnc(SCC(=O)NCC3CCCO3)c2c1C nan
20888842 46136 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 9 1.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
CHEMBL1533752 46136 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 9 1.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
7677714 46138 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 5 3.2 Cc1ccc(C(=O)NCc2nnc3c(C(F)(F)F)cc(Cl)cn23)o1 nan
CHEMBL1533761 46138 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 5 3.2 Cc1ccc(C(=O)NCc2nnc3c(C(F)(F)F)cc(Cl)cn23)o1 nan
16018626 46185 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1ccc(NC(=O)CSc2nncn3c2cc2occc23)c(OC)c1 nan
CHEMBL1534283 46185 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1ccc(NC(=O)CSc2nncn3c2cc2occc23)c(OC)c1 nan
2415319 46187 None 26 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 5 4.0 O=C(O)c1ccccc1Sc1ncnc2sc3c(c12)CCC3 nan
CHEMBL1534296 46187 None 26 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 5 4.0 O=C(O)c1ccccc1Sc1ncnc2sc3c(c12)CCC3 nan
15988400 46216 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 7 3.0 CCn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
CHEMBL1534534 46216 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 7 3.0 CCn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
3559456 46319 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Br)c2)no1 nan
CHEMBL1535636 46319 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Br)c2)no1 nan
752859 46342 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 6 2.6 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccccc2)n1 nan
CHEMBL1535864 46342 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 6 2.6 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccccc2)n1 nan
1258096 46378 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 7 3.1 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)c(Cl)c1 nan
CHEMBL1536340 46378 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 7 3.1 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)c(Cl)c1 nan
5911396 46402 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 8 3.5 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)OCCO4)C2c2ccc(F)cc2)s1 nan
CHEMBL1536589 46402 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 8 3.5 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)OCCO4)C2c2ccc(F)cc2)s1 nan
2968508 46504 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 3.4 O=C(COc1ccccc1)NC(=S)Nc1cccc2cc(O)ccc12 nan
CHEMBL1537461 46504 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 3.4 O=C(COc1ccccc1)NC(=S)Nc1cccc2cc(O)ccc12 nan
973903 46664 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 3 7 1.5 O=C(NNc1nc(=O)c2cccnc2s1)c1ccccc1O nan
CHEMBL1538711 46664 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 3 7 1.5 O=C(NNc1nc(=O)c2cccnc2s1)c1ccccc1O nan
4786350 46717 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 4 0 6 2.6 COC(=O)c1ccc(COc2ncnc3ccccc23)o1 nan
CHEMBL1539182 46717 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 4 0 6 2.6 COC(=O)c1ccc(COc2ncnc3ccccc23)o1 nan
4199276 46724 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 10 -0.3 Cn1c(=O)c2nc(NNC(=O)c3ccc([N+](=O)[O-])cc3)cnc2n(C)c1=O nan
CHEMBL1539261 46724 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 10 -0.3 Cn1c(=O)c2nc(NNC(=O)c3ccc([N+](=O)[O-])cc3)cnc2n(C)c1=O nan
20957177 46749 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 8 2.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccccc1Cl nan
CHEMBL1539515 46749 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 8 2.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccccc1Cl nan
775376 47034 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 7 -0.1 Cn1c(=O)c2c(ncn2CC(=O)NC2CCCCC2)n(C)c1=O nan
CHEMBL1541812 47034 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 7 -0.1 Cn1c(=O)c2c(ncn2CC(=O)NC2CCCCC2)n(C)c1=O nan
2027988 47124 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)cc1 nan
CHEMBL1542663 47124 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)cc1 nan
7190638 47295 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 7 2.9 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccccc1 nan
CHEMBL1544038 47295 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 7 2.9 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccccc1 nan
5291252 47352 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 4 4.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
CHEMBL1544399 47352 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 4 4.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
3531704 47412 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 5.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccc(Oc3ccccc3)c2)no1 nan
CHEMBL1544885 47412 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 5.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccc(Oc3ccccc3)c2)no1 nan
1254436 47449 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 10 -0.3 Cn1c(=O)c2c(nc(Br)n2Cc2nnc(N)s2)n(C)c1=O nan
CHEMBL1545144 47449 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 10 -0.3 Cn1c(=O)c2c(nc(Br)n2Cc2nnc(N)s2)n(C)c1=O nan
20923178 47492 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)o1 nan
CHEMBL1545457 47492 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)o1 nan
2827527 47505 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 0 2 3.2 Cc1ccc2c(ccc(=S)n2C)c1 nan
CHEMBL1545583 47505 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 0 2 3.2 Cc1ccc2c(ccc(=S)n2C)c1 nan
4114707 47557 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2nnc(SCC(=O)NCC3CCCO3)n2c2ccccc12 nan
CHEMBL1546017 47557 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2nnc(SCC(=O)NCC3CCCO3)n2c2ccccc12 nan
6620293 47635 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 0 5 3.8 O=C(C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1)N1CCCC1 nan
CHEMBL1546743 47635 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 0 5 3.8 O=C(C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1)N1CCCC1 nan
2341870 47645 None 1 Human Functional pPotency = 4.8 4.8 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 0 5 4.1 Cc1ccc(C)n1-c1ccc(-c2nnc3n2CCCCC3)s1 nan
CHEMBL1546820 47645 None 1 Human Functional pPotency = 4.8 4.8 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 0 5 4.1 Cc1ccc(C)n1-c1ccc(-c2nnc3n2CCCCC3)s1 nan
2150404 47888 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 1 1 4 3.8 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccccc1 nan
CHEMBL1549101 47888 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 1 1 4 3.8 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccccc1 nan
2482804 47991 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 5 2 8 -0.4 C=CCNC(=O)NC(=O)COC(=O)c1nc2nccc(C)n2n1 nan
CHEMBL1549963 47991 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 5 2 8 -0.4 C=CCNC(=O)NC(=O)COC(=O)c1nc2nccc(C)n2n1 nan
7184632 48120 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1550958 48120 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
16030519 48138 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)cc1 nan
CHEMBL1551209 48138 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)cc1 nan
1116231 48242 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.4 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(Cl)c2Cl)n(C)c1=O nan
CHEMBL1552691 48242 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.4 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(Cl)c2Cl)n(C)c1=O nan
16031533 48252 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 6 4.5 CCc1ccccc1NC(=O)CSc1nnc(-c2ccc(OC)cc2)s1 nan
CHEMBL1552858 48252 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 6 4.5 CCc1ccccc1NC(=O)CSc1nnc(-c2ccc(OC)cc2)s1 nan
16033232 48262 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2cccc(Cl)c2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1552980 48262 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2cccc(Cl)c2)sc2ncnc(N(C)C3CCCCC3)c12 nan
2136319 48284 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
CHEMBL1553213 48284 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
16018758 48343 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 5 4.5 Cc1cc2c(cc3c(SCc4cccc(F)c4)nnc(C)n32)o1 nan
CHEMBL1554096 48343 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 5 4.5 Cc1cc2c(cc3c(SCc4cccc(F)c4)nnc(C)n32)o1 nan
4808155 48521 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 7 0.7 Cn1c(=O)c2c(ncn2CCOc2ccc(F)cc2)n(C)c1=O nan
CHEMBL1556293 48521 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 7 0.7 Cn1c(=O)c2c(ncn2CCOc2ccc(F)cc2)n(C)c1=O nan
664905 48660 None 12 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 3.4 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccco1 nan
CHEMBL1557499 48660 None 12 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 3.4 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccco1 nan
846378 48774 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 5 3.8 CN(C)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
CHEMBL1558527 48774 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 5 3.8 CN(C)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
20970070 48910 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 7 2.8 CCOc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
CHEMBL1559703 48910 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 7 2.8 CCOc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
749967 49111 None 40 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 208 2 1 5 2.0 COc1ccccc1-c1nnc(S)o1 nan
CHEMBL1561641 49111 None 40 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 208 2 1 5 2.0 COc1ccccc1-c1nnc(S)o1 nan
2816163 49282 None 17 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 2 0 7 0.8 CCOC(=O)c1nnn2c3ccccc3c(=O)n(C)c12 nan
CHEMBL1563125 49282 None 17 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 2 0 7 0.8 CCOC(=O)c1nnn2c3ccccc3c(=O)n(C)c12 nan
754624 49376 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 0 6 3.0 O=c1c2c(-c3ccc([N+](=O)[O-])cc3)csc2nc2n1CCC2 nan
CHEMBL1563900 49376 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 0 6 3.0 O=c1c2c(-c3ccc([N+](=O)[O-])cc3)csc2nc2n1CCC2 nan
20923125 49517 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)cc1 nan
CHEMBL1565225 49517 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)cc1 nan
5818870 49526 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4cccnc4)C3c3ccccc3F)ccc2O1 nan
CHEMBL1565288 49526 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4cccnc4)C3c3ccccc3F)ccc2O1 nan
702333 50013 None 12 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 0 1 3 2.9 Cn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
CHEMBL1569119 50013 None 12 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 0 1 3 2.9 Cn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
1072636 50351 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 1.0 CCn1c(SCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1572163 50351 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 1.0 CCn1c(SCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)nc2c1c(=O)n(C)c(=O)n2C nan
4912148 50359 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 8 3.6 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2)s1 nan
CHEMBL1572210 50359 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 8 3.6 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2)s1 nan
719137 50380 None 12 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 1 1 3 3.4 CCn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
CHEMBL1572461 50380 None 12 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 1 1 3 3.4 CCn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
22518619 50586 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 8 3.8 CC(C)OCCCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nc2nccnc2c1=O nan
CHEMBL1574369 50586 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 8 3.8 CC(C)OCCCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nc2nccnc2c1=O nan
3516975 50675 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2sccc2Br)nc(-n2cccc2)n1 nan
CHEMBL1575467 50675 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2sccc2Br)nc(-n2cccc2)n1 nan
2109682 50701 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 11 0.2 Cc1ccc(C)c(-n2nnnc2SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
CHEMBL1575697 50701 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 11 0.2 Cc1ccc(C)c(-n2nnnc2SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
16189479 50820 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 0 8 -0.2 Cn1c(=O)c(=O)n(C)c2cc(S(=O)(=O)N3CC(=O)N(CCc4ccccc4)C(=O)C3)ccc21 nan
CHEMBL1576683 50820 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 0 8 -0.2 Cn1c(=O)c(=O)n(C)c2cc(S(=O)(=O)N3CC(=O)N(CCc4ccccc4)C(=O)C3)ccc21 nan
1173783 50855 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCC(=O)Nc1ccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2CC)cc1 nan
CHEMBL1577034 50855 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCC(=O)Nc1ccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2CC)cc1 nan
2960985 51066 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
5740252 51066 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
9587839 51066 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
CHEMBL1578738 51066 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
3221467 51078 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 8 1 6 3.0 CCOC(=O)CNC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
CHEMBL1578803 51078 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 8 1 6 3.0 CCOC(=O)CNC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
6409200 51214 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 2 5 3.4 O=C(O)c1ccccc1CSc1n[nH]c2c3ccccc3nc-2n1 nan
CHEMBL1580121 51214 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 2 5 3.4 O=C(O)c1ccccc1CSc1n[nH]c2c3ccccc3nc-2n1 nan
20957463 51230 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 10 2 7 2.5 O=C(CCc1nnc2ccc(NCCCN3CCCC3=O)nn12)NCc1ccccc1Cl nan
CHEMBL1580225 51230 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 10 2 7 2.5 O=C(CCc1nnc2ccc(NCCCN3CCCC3=O)nn12)NCc1ccccc1Cl nan
929935 51314 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 1 2 6 4.2 CC(C)c1nc2sc3c(O)nc(S)nc3c2c2c1CCCC2 nan
CHEMBL1580962 51314 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 1 2 6 4.2 CC(C)c1nc2sc3c(O)nc(S)nc3c2c2c1CCCC2 nan
3220371 51322 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 6 2.9 CC(C)C(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
CHEMBL1581023 51322 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 6 2.9 CC(C)C(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
2916260 51399 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 10 0.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1581657 51399 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 10 0.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
1324776 51495 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 9 2 8 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2cc(OC)nc(OC)n2)cc1 nan
CHEMBL1582422 51495 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 9 2 8 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2cc(OC)nc(OC)n2)cc1 nan
4976300 51668 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 9 4.0 CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(OC)c2)s1 nan
CHEMBL1583844 51668 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 9 4.0 CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(OC)c2)s1 nan
5083492 51807 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 13 1 5 5.1 CC[N+](CC)(CCCCS(=O)(=O)[O-])CCNP1(=O)C=C(c2ccccc2)OC(c2ccccc2)=C1 nan
CHEMBL1585012 51807 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 13 1 5 5.1 CC[N+](CC)(CCCCS(=O)(=O)[O-])CCNP1(=O)C=C(c2ccccc2)OC(c2ccccc2)=C1 nan
6624747 52038 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 2.6 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccccc3)nnc12 nan
CHEMBL1586923 52038 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 2.6 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccccc3)nnc12 nan
2384712 52348 None 21 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 3 4.8 Brc1ccc(-c2nc3ccccc3s2)s1 nan
CHEMBL1589567 52348 None 21 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 3 4.8 Brc1ccc(-c2nc3ccccc3s2)s1 nan
16030403 52423 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 4 4.8 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCC(C)C)cc1 nan
CHEMBL1590296 52423 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 4 4.8 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCC(C)C)cc1 nan
16022890 52474 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 2 6 5.2 COc1cc2cc(CNc3ccccc3)c(=O)n(CC(=O)Nc3cccc(Cl)c3C)c2cc1OC nan
CHEMBL1590948 52474 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 2 6 5.2 COc1cc2cc(CNc3ccccc3)c(=O)n(CC(=O)Nc3cccc(Cl)c3C)c2cc1OC nan
16029271 52560 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 4 0 8 1.5 CCOC(=O)c1noc2ncn(Cc3cccc(C#N)c3)c(=O)c12 nan
CHEMBL1592100 52560 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 4 0 8 1.5 CCOC(=O)c1noc2ncn(Cc3cccc(C#N)c3)c(=O)c12 nan
3431356 52581 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 9 2 4 5.8 CCc1ccc(Nc2cc(C(=O)NCCCN(C)c3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1592367 52581 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 9 2 4 5.8 CCc1ccc(Nc2cc(C(=O)NCCCN(C)c3ccccc3)c3ccccc3n2)cc1 nan
16331440 52606 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 0 6 1.9 CC(C(=O)OCC(=O)N(C)C1(C#N)CCCCC1)N1C(=O)c2ccccc2C1=O nan
CHEMBL1592707 52606 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 0 6 1.9 CC(C(=O)OCC(=O)N(C)C1(C#N)CCCCC1)N1C(=O)c2ccccc2C1=O nan
22518595 52737 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.0 COc1ccccc1NC(=O)CSc1nc2nccnc2c(=O)n1Cc1cccs1 nan
CHEMBL1594419 52737 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.0 COc1ccccc1NC(=O)CSc1nc2nccnc2c(=O)n1Cc1cccs1 nan
3630300 52749 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 5 4.9 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(Cl)cc2)n1 nan
CHEMBL1594498 52749 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 5 4.9 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(Cl)cc2)n1 nan
16018788 52870 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 CCc1cccc(C)c1NC(=O)CSc1nnc(CC)n2c1cc1occc12 nan
CHEMBL1595485 52870 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 CCc1cccc(C)c1NC(=O)CSc1nnc(CC)n2c1cc1occc12 nan
135454734 52949 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 3 9 1.2 Nc1cc(O)nc(SCC(=O)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2Cl)n1 nan
CHEMBL1596208 52949 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 3 9 1.2 Nc1cc(O)nc(SCC(=O)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2Cl)n1 nan
3151377 52966 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCCC1 nan
CHEMBL1596336 52966 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCCC1 nan
2743162 53064 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)cc(Cl)c2)n1 nan
CHEMBL1597261 53064 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)cc(Cl)c2)n1 nan
5175738 53110 None 51 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 3 2 5 6.0 Nc1c(C(=O)Nc2ccc(F)cc2)sc2nc(-c3cccs3)cc(C(F)(F)F)c12 nan
CHEMBL1597711 53110 None 51 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 3 2 5 6.0 Nc1c(C(=O)Nc2ccc(F)cc2)sc2nc(-c3cccs3)cc(C(F)(F)F)c12 nan
16018618 53123 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)cc(NC(=O)CSc2nncn3c2cc2occc23)c1 nan
CHEMBL1597835 53123 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)cc(NC(=O)CSc2nncn3c2cc2occc23)c1 nan
2931308 53227 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 2.4 COC(=O)c1cc(C)sc1NC(=O)C1CC=CCC1C(=O)O nan
CHEMBL1598795 53227 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 2.4 COC(=O)c1cc(C)sc1NC(=O)C1CC=CCC1C(=O)O nan
16033260 53243 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1598947 53243 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
7202413 53411 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 8 1.2 Cc1nnc2sc(SCC(=O)N3CCC(C)CC3)nn2c1=O nan
CHEMBL1600469 53411 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 8 1.2 Cc1nnc2sc(SCC(=O)N3CCC(C)CC3)nn2c1=O nan
893043 53435 None 11 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 3 2.4 O=c1[nH]c(=S)c2c(n1-c1ccccc1)CCC2 nan
CHEMBL1600661 53435 None 11 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 3 2.4 O=c1[nH]c(=S)c2c(n1-c1ccccc1)CCC2 nan
15988297 53597 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.1 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1F nan
CHEMBL1602305 53597 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.1 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1F nan
20923199 53630 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N(C)Cc1ccco1 nan
CHEMBL1602602 53630 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N(C)Cc1ccco1 nan
2138501 53634 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 7 1.0 COc1ccc(C=O)cc1Cn1cnc2c(cnn2C)c1=O nan
CHEMBL1602628 53634 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 7 1.0 COc1ccc(C=O)cc1Cn1cnc2c(cnn2C)c1=O nan
16301839 53636 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 11 1.2 Cn1c(N)c(C(=O)CSc2nnc(NC3CCCCC3)s2)c(=O)n(C)c1=O nan
CHEMBL1602634 53636 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 11 1.2 Cn1c(N)c(C(=O)CSc2nnc(NC3CCCCC3)s2)c(=O)n(C)c1=O nan
2960993 53847 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
5740253 53847 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
9587840 53847 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
CHEMBL1604402 53847 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
5925277 53864 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 8 1.2 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCCOC)CC1 nan
CHEMBL1604541 53864 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 8 1.2 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCCOC)CC1 nan
2928283 53912 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCC4)c3nc12 nan
CHEMBL1605019 53912 None 13 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCC4)c3nc12 nan
6460757 54499 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 6 2.4 Cc1cc2c(SCC(=O)NCC3CCCO3)ncnc2s1 nan
CHEMBL1609708 54499 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 6 2.4 Cc1cc2c(SCC(=O)NCC3CCCO3)ncnc2s1 nan
15991073 54630 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
CHEMBL1610897 54630 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
7889635 54688 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 7 1.5 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3)cc(=O)n12 nan
CHEMBL1611331 54688 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 7 1.5 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3)cc(=O)n12 nan
778300 54863 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 2 1 10 -1.1 Cn1c(=O)c2c(ncn2Cc2nnc(N)s2)n(C)c1=O nan
CHEMBL1612871 54863 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 2 1 10 -1.1 Cn1c(=O)c2c(ncn2Cc2nnc(N)s2)n(C)c1=O nan
705485 55260 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
CHEMBL1321656 55260 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
CHEMBL1617945 55260 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
20279 55373 None 52 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
CHEMBL1619 55373 None 52 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
1187262 55647 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
CHEMBL1462585 55647 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
CHEMBL1621394 55647 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
44143728 60267 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
CHEMBL1553539 60267 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
CHEMBL1741041 60267 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
135641876 72189 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 10 -0.7 COc1cc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1O nan
CHEMBL1979668 72189 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 10 -0.7 COc1cc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1O nan
135475570 72683 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 7 2.3 CCN(CC)S(=O)(=O)c1cccc(N/N=C2/C(=O)Oc3ccccc3C2=O)c1 nan
CHEMBL1995496 72683 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 7 2.3 CCN(CC)S(=O)(=O)c1cccc(N/N=C2/C(=O)Oc3ccccc3C2=O)c1 nan
9632269 72946 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2cccnc2)n(C)c1=O nan
CHEMBL2004582 72946 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2cccnc2)n(C)c1=O nan
9553490 108053 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 9 -0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C/c2ccco2)n(C)c1=O nan
CHEMBL3194107 108053 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 9 -0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C/c2ccco2)n(C)c1=O nan
6905987 108395 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.5 Sc1nnc(-c2ccccn2)n1/N=C/c1ccc(-c2ccccc2Br)o1 nan
CHEMBL3198000 108395 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.5 Sc1nnc(-c2ccccn2)n1/N=C/c1ccc(-c2ccccc2Br)o1 nan
540540 108476 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 7 1.1 CC(=O)/N=c1\sc2nc3ccccc3nc2n1N(C(C)=O)C(C)=O nan
CHEMBL3198706 108476 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 7 1.1 CC(=O)/N=c1\sc2nc3ccccc3nc2n1N(C(C)=O)C(C)=O nan
5339637 108565 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 7 2 5 1.4 O=C(COc1ccccc1)NCC(=O)N/N=C/c1cccs1 nan
CHEMBL3199816 108565 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 7 2 5 1.4 O=C(COc1ccccc1)NCC(=O)N/N=C/c1cccs1 nan
9553411 108958 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 -0.0 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccccc2)n(C)c1=O nan
CHEMBL3210887 108958 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 -0.0 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccccc2)n(C)c1=O nan
9634938 108968 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccncc2)n(C)c1=O nan
CHEMBL3211064 108968 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccncc2)n(C)c1=O nan
1116825 184369 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 2.4 Cc1ccnc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
CHEMBL483773 184369 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 2.4 Cc1ccnc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
7190719 203403 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1ccc(CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL601822 203403 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1ccc(CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
3259 23368 None 46 Human Functional pPotency = 3.8 3.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 836 0 2 5 6.1 O=C1OC2(c3ccccc31)c1cc(I)c(O)c(I)c1Oc1c2cc(I)c(O)c1I nan
CHEMBL1332616 23368 None 46 Human Functional pPotency = 3.8 3.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 836 0 2 5 6.1 O=C1OC2(c3ccccc31)c1cc(I)c(O)c(I)c1Oc1c2cc(I)c(O)c1I nan
3228920 29746 None 3 Human Functional pPotency = 3.8 3.8 -31 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 2 5 5.9 O=C(CSc1nc(-c2ccccc2F)nc2nc[nH]c12)Nc1c(Cl)cc(Cl)cc1Cl nan
CHEMBL1386739 29746 None 3 Human Functional pPotency = 3.8 3.8 -31 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 2 5 5.9 O=C(CSc1nc(-c2ccccc2F)nc2nc[nH]c12)Nc1c(Cl)cc(Cl)cc1Cl nan
2099 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
4740 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
4740.0 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
7095 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
CHEMBL628 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
DB00806 3046 None 54 Human Functional pPotency = 4.8 4.8 -234 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
3220395 19634 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 6 2.7 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
CHEMBL1300380 19634 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 6 2.7 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
16452711 19756 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 8 2.9 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)c1C nan
CHEMBL1301248 19756 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 8 2.9 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)c1C nan
4134237 20034 None 6 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 4 3.0 CC1CCCN(C(=O)CSc2cnc3ccccc3n2)C1 nan
CHEMBL1303471 20034 None 6 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 4 3.0 CC1CCCN(C(=O)CSc2cnc3ccccc3n2)C1 nan
2816749 20243 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 0 6 1.5 CCOC(=O)N1CCc2c(sc3ncn(C)c(=O)c23)C1 nan
CHEMBL1305245 20243 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 0 6 1.5 CCOC(=O)N1CCc2c(sc3ncn(C)c(=O)c23)C1 nan
225068 20346 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 2 6 0.5 CC(=O)Nc1ccc(Cc2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)cc1 nan
CHEMBL1306052 20346 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 2 6 0.5 CC(=O)Nc1ccc(Cc2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)cc1 nan
2377168 20684 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 6 1.7 NS(=O)(=O)c1ccc(CCNC(=O)CSc2ncnc3ccccc23)cc1 nan
CHEMBL1308771 20684 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 6 1.7 NS(=O)(=O)c1ccc(CCNC(=O)CSc2ncnc3ccccc23)cc1 nan
6311448 20903 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 2 6 2.6 CNc1ccc(/C=C(\C#N)C(=O)Nc2ccccn2)cc1[N+](=O)[O-] nan
CHEMBL1310631 20903 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 2 6 2.6 CNc1ccc(/C=C(\C#N)C(=O)Nc2ccccn2)cc1[N+](=O)[O-] nan
4454085 21109 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 8 1.1 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
CHEMBL1312229 21109 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 8 1.1 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
3269960 21171 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 9 3.7 O=C(O)CCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
CHEMBL1312645 21171 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 9 3.7 O=C(O)CCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
5811072 21204 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 7 3.8 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
CHEMBL1312900 21204 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 7 3.8 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
3719872 21285 None 12 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 3.8 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)no1 nan
CHEMBL1313510 21285 None 12 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 3.8 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)no1 nan
7151338 21364 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 2.8 CCS(=O)(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 nan
CHEMBL1314161 21364 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 2.8 CCS(=O)(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 nan
16010497 21406 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.0 COc1ccc(CCNC(=O)c2cnc3ccc(C)cn3c2=O)cc1OC nan
CHEMBL1314605 21406 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.0 COc1ccc(CCNC(=O)c2cnc3ccc(C)cn3c2=O)cc1OC nan
4119285 21488 None 11 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
CHEMBL1315733 21488 None 11 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
16020283 21526 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 5 4.1 CCOc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3s2)cc1 nan
CHEMBL1316147 21526 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 5 4.1 CCOc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3s2)cc1 nan
2645859 21559 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 6 2.6 Cc1cnc(C(=O)OCC(=O)c2ccc(Br)s2)cn1 nan
CHEMBL1316688 21559 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 6 2.6 Cc1cnc(C(=O)OCC(=O)c2ccc(Br)s2)cn1 nan
16019079 21633 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.2 CCc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1317634 21633 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.2 CCc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
16025698 21661 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 6.1 CC(NC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1)c1ccccc1 nan
CHEMBL1317991 21661 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 6.1 CC(NC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1)c1ccccc1 nan
16018836 21718 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 1 6 4.6 O=C(CSc1nncn2c1cc1sccc12)Nc1ccc(Br)cc1F nan
CHEMBL1318579 21718 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 1 6 4.6 O=C(CSc1nncn2c1cc1sccc12)Nc1ccc(Br)cc1F nan
658390 22141 None 16 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 2.7 CSc1sc(C(=O)O)c2c1C(=O)CCC2 nan
CHEMBL132222 22141 None 16 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 2.7 CSc1sc(C(=O)O)c2c1C(=O)CCC2 nan
4302597 22375 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 6 3.1 Cc1c(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)nn1C nan
CHEMBL1324305 22375 None 10 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 6 3.1 Cc1c(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)nn1C nan
16825458 22631 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1OC nan
CHEMBL1326698 22631 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1OC nan
961104 22938 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 5 2 5 1.8 CCOC(=O)c1[nH]cnc1C(=O)Nc1ccccc1OC nan
CHEMBL1329229 22938 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 5 2 5 1.8 CCOC(=O)c1[nH]cnc1C(=O)Nc1ccccc1OC nan
753118 23187 None 42 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1331202 23187 None 42 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1532594 23187 None 42 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
5302178 23661 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
CHEMBL1334923 23661 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
4213677 23762 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 2 9 2.3 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc5c(c4)OCO5)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1335629 23762 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 2 9 2.3 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc5c(c4)OCO5)c(=N)n(CC4CCCO4)c3nc12 nan
2410320 23997 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 6 2.5 Cc1ccc(S(=O)(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
CHEMBL1337652 23997 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 6 2.5 Cc1ccc(S(=O)(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
6624813 24315 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 7 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCCCC3)nnc12 nan
CHEMBL1340556 24315 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 7 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCCCC3)nnc12 nan
16189291 24467 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 0 8 2.6 CCOC(=O)C(CC)Sc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1341871 24467 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 0 8 2.6 CCOC(=O)C(CC)Sc1ccc2nnc(-c3cccnc3)n2n1 nan
2835302 24653 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 1 2 4 3.4 CCC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
CHEMBL1343308 24653 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 1 2 4 3.4 CCC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
9115295 24687 None 23 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 4 4.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1C(F)(F)F nan
CHEMBL1343609 24687 None 23 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 4 4.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1C(F)(F)F nan
874496 24747 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 4 2 2 4.0 CC(C)C(=O)Nc1ccc(Nc2ccccc2)cc1 nan
CHEMBL1344171 24747 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 4 2 2 4.0 CC(C)C(=O)Nc1ccc(Nc2ccccc2)cc1 nan
5040775 24767 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 5 1.5 CC1CCCCC1NC(=O)Cn1nnc2ccccc2c1=O nan
CHEMBL1344340 24767 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 5 1.5 CC1CCCCC1NC(=O)Cn1nnc2ccccc2c1=O nan
7190697 24836 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 9 1.0 CCOC(=O)CNC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1344913 24836 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 9 1.0 CCOC(=O)CNC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
1279973 24881 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 10 0.8 COCc1cc(C)nc(Sc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1C#N nan
CHEMBL1345308 24881 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 10 0.8 COCc1cc(C)nc(Sc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1C#N nan
16187878 24961 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 8 3.6 CCOC(=O)CC(NC(=O)CCc1c(C)nc2nc(C)nn2c1C)c1ccc(OC(C)C)cc1 nan
CHEMBL1346041 24961 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 8 3.6 CCOC(=O)CC(NC(=O)CCc1c(C)nc2nc(C)nn2c1C)c1ccc(OC(C)C)cc1 nan
4911180 24963 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 8 4.3 C=CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
CHEMBL1346060 24963 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 8 4.3 C=CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
6626039 25045 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 7 1 8 2.2 CCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
CHEMBL1346717 25045 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 7 1 8 2.2 CCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
4884017 25068 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 0 6 2.9 CCN1c2ccc(S(=O)(=O)N3CCOCC3)cc2N(Cc2ccc(OC)cc2)C1C nan
CHEMBL1346905 25068 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 0 6 2.9 CCN1c2ccc(S(=O)(=O)N3CCOCC3)cc2N(Cc2ccc(OC)cc2)C1C nan
5916900 25362 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1349404 25362 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
2421577 25455 None 3 Human Functional pPotency = 4.8 4.8 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 0 5 3.2 COC(=O)CCc1c(C)c(C(=O)c2ccco2)c2ccccn12 nan
CHEMBL1350197 25455 None 3 Human Functional pPotency = 4.8 4.8 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 0 5 3.2 COC(=O)CCc1c(C)c(C(=O)c2ccco2)c2ccccn12 nan
2429966 25511 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 0 7 2.8 COc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1OC nan
CHEMBL1350669 25511 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 0 7 2.8 COc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1OC nan
5921143 25700 None 14 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 10 1.5 CCCN1C(=O)/C(=C/c2c(N3CCNC(=O)C3CC(=O)OC)nc3c(C)cccn3c2=O)SC1=S nan
CHEMBL1352285 25700 None 14 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 10 1.5 CCCN1C(=O)/C(=C/c2c(N3CCNC(=O)C3CC(=O)OC)nc3c(C)cccn3c2=O)SC1=S nan
2926991 25731 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 4.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)n1 nan
CHEMBL1352465 25731 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 4.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)n1 nan
16015204 25996 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 4.5 COC(=O)c1c(-c2cccs2)csc1NC(=O)c1ccc(OC)c(OC)c1 nan
CHEMBL1354415 25996 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 4.5 COC(=O)c1c(-c2cccs2)csc1NC(=O)c1ccc(OC)c(OC)c1 nan
16030461 26048 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 4 4.2 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1355113 26048 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 4 4.2 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
23602530 26130 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 5 2.2 Cc1ccc(Cn2c(CCC(=O)O)nc3ncccc3c2=O)cc1 nan
CHEMBL1356159 26130 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 5 2.2 Cc1ccc(Cn2c(CCC(=O)O)nc3ncccc3c2=O)cc1 nan
16018072 26183 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 7 1 4 3.8 Cc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
CHEMBL1356862 26183 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 7 1 4 3.8 Cc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
1077055 26225 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 8 0.3 CC(=O)c1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1357427 26225 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 8 0.3 CC(=O)c1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
16021425 26238 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)c1 nan
CHEMBL1357639 26238 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)c1 nan
16030521 26252 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)c1 nan
CHEMBL1357883 26252 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)c1 nan
16030369 26277 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 4.9 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(C)cc2)c1 nan
CHEMBL1358199 26277 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 4.9 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(C)cc2)c1 nan
15987639 26303 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 4 5.5 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc2ccccc2F)cc1F nan
CHEMBL1358546 26303 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 4 5.5 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc2ccccc2F)cc1F nan
881482 26832 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 3 3.7 O=S(=O)(Nc1ccccn1)c1ccc(Cl)c2ccccc12 nan
CHEMBL1363117 26832 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 3 3.7 O=S(=O)(Nc1ccccn1)c1ccc(Cl)c2ccccc12 nan
3193431 26879 None 1 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 7 0 8 4.3 COc1ccc(Cn2nnnc2C(c2ccc3ncccc3c2)N2CCN(C3CCCCC3)CC2)cc1 nan
CHEMBL1363552 26879 None 1 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 7 0 8 4.3 COc1ccc(Cn2nnnc2C(c2ccc3ncccc3c2)N2CCN(C3CCCCC3)CC2)cc1 nan
1261960 26883 None 6 Human Functional pPotency = 4.8 4.8 -7 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 5 3.5 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)cc1 nan
CHEMBL1363571 26883 None 6 Human Functional pPotency = 4.8 4.8 -7 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 5 3.5 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)cc1 nan
7190718 26995 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1cccc(CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1364582 26995 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1cccc(CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
20884309 27002 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 8 1.1 CCc1nn(CC(=O)NCCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
CHEMBL1364643 27002 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 8 1.1 CCc1nn(CC(=O)NCCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
4152428 27037 None 5 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
CHEMBL1364957 27037 None 5 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
5109926 27071 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 2 8 2.6 COc1ccc(CCn2c(=N)c(C(=O)NCC3CCCO3)cc3c(=O)n4cccc(C)c4nc32)cc1 nan
CHEMBL1365247 27071 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 2 8 2.6 COc1ccc(CCn2c(=N)c(C(=O)NCC3CCCO3)cc3c(=O)n4cccc(C)c4nc32)cc1 nan
2959558 27074 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 3.3 CCOC(=O)N1CCN(C(=O)COc2ccc3ccccc3c2Br)CC1 nan
CHEMBL1365264 27074 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 3.3 CCOC(=O)N1CCN(C(=O)COc2ccc3ccccc3c2Br)CC1 nan
15988059 27130 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 1 10 2.6 COC(=O)c1cccc(Nc2nn3c(=O)c4cc5c(cc4nc3s2)OCO5)c1 nan
CHEMBL1365674 27130 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 1 10 2.6 COC(=O)c1cccc(Nc2nn3c(=O)c4cc5c(cc4nc3s2)OCO5)c1 nan
16015914 27136 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 2 0 4 6.1 Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)oc2cc(Br)ccc12 nan
CHEMBL1365703 27136 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 2 0 4 6.1 Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)oc2cc(Br)ccc12 nan
912209 27149 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 3 5 1.9 NC(S)=Nc1cccc(-c2nnc(S)o2)c1 nan
CHEMBL1365893 27149 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 3 5 1.9 NC(S)=Nc1cccc(-c2nnc(S)o2)c1 nan
3719648 27725 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 4.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc3ccccc23)s1 nan
CHEMBL1370349 27725 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 4.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc3ccccc23)s1 nan
1775727 28004 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 0 5 4.3 COc1ccccc1CN1COc2ccc3c(oc(=O)c4ccccc43)c2C1 nan
CHEMBL1372393 28004 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 0 5 4.3 COc1ccccc1CN1COc2ccc3c(oc(=O)c4ccccc43)c2C1 nan
16193912 28446 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 6 4.8 CCCCN(CC)CCCNC(=O)C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1 nan
CHEMBL1375345 28446 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 6 4.8 CCCCN(CC)CCCNC(=O)C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1 nan
2818996 28592 None 2 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.9 COc1ccc(-c2c(C#N)c(N)nc(Sc3ccc(Cl)cc3)c2C#N)cc1 nan
CHEMBL1376612 28592 None 2 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.9 COc1ccc(-c2c(C#N)c(N)nc(Sc3ccc(Cl)cc3)c2C#N)cc1 nan
20876288 29200 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 5 3.5 Cc1ccc(CN2CCSc3ccc(C(=O)NCCCN4CCN(C)CC4)cc32)cc1 nan
CHEMBL1382060 29200 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 5 3.5 Cc1ccc(CN2CCSc3ccc(C(=O)NCCCN4CCN(C)CC4)cc32)cc1 nan
4902824 29272 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
CHEMBL1382669 29272 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
408543 29625 None 26 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 3 1 3 2.4 O=C(O)CSc1ccc2ccccc2n1 nan
CHEMBL1385852 29625 None 26 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 3 1 3 2.4 O=C(O)CSc1ccc2ccccc2n1 nan
16452903 29650 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1ccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)cc1 nan
CHEMBL1386060 29650 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1ccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)cc1 nan
5866058 29675 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)c1 nan
CHEMBL1386260 29675 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)c1 nan
2219052 30152 None 6 Human Functional pPotency = 4.8 4.8 -3 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 6 4.2 CCCCn1nnc(NC(=O)c2sc3cc(Cl)ccc3c2Cl)n1 nan
CHEMBL1389959 30152 None 6 Human Functional pPotency = 4.8 4.8 -3 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 6 4.2 CCCCn1nnc(NC(=O)c2sc3cc(Cl)ccc3c2Cl)n1 nan
974402 30280 None 9 Human Functional pPotency = 4.8 4.8 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 2 2 3.4 CC(C)NC(=S)NC(=O)c1ccc(-c2ccccc2)cc1 nan
CHEMBL1391097 30280 None 9 Human Functional pPotency = 4.8 4.8 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 2 2 3.4 CC(C)NC(=S)NC(=O)c1ccc(-c2ccccc2)cc1 nan
4385170 30424 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 4 4.9 CCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1392345 30424 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 4 4.9 CCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
2492440 30457 None 20 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 3.4 Cc1ccccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
CHEMBL1392606 30457 None 20 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 3.4 Cc1ccccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
7207181 30505 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.9 O=C(CSc1ccc(-c2ccco2)nn1)NCc1ccc2c(c1)OCO2 nan
CHEMBL1393087 30505 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.9 O=C(CSc1ccc(-c2ccco2)nn1)NCc1ccc2c(c1)OCO2 nan
16025764 30717 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 0 3 4.6 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCCCC2)s1 nan
CHEMBL1395096 30717 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 0 3 4.6 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCCCC2)s1 nan
5839687 30860 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 1.7 COCCNC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O nan
CHEMBL1397071 30860 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 1.7 COCCNC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O nan
5789902 30922 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 5 4.0 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
CHEMBL1397920 30922 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 5 4.0 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
3288231 30943 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 4 5.7 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
CHEMBL1398189 30943 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 4 5.7 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
15991174 30973 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 3 3 7 1.6 Cc1cc(Nc2ccc(C(=O)O)c(O)c2)n2ncnc2n1 nan
CHEMBL1398548 30973 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 3 3 7 1.6 Cc1cc(Nc2ccc(C(=O)O)c(O)c2)n2ncnc2n1 nan
16025760 31105 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1399794 31105 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
135444909 31165 None 7 Human Functional pPotency = 4.8 4.8 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 8 3 10 3.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)cc2)n1 nan
CHEMBL1400344 31165 None 7 Human Functional pPotency = 4.8 4.8 -4 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 8 3 10 3.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)cc2)n1 nan
16023027 31192 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
CHEMBL1400601 31192 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
2005962 31198 None 5 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 7 3.5 CC(C)OCCCN1CN(S(=O)(=O)c2cccs2)c2nc3ccccc3nc21 nan
CHEMBL1400661 31198 None 5 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 7 3.5 CC(C)OCCCN1CN(S(=O)(=O)c2cccs2)c2nc3ccccc3nc21 nan
4176332 31235 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 3 1 5 3.6 CN1CCN(NC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)CC1 nan
CHEMBL1401042 31235 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 3 1 5 3.6 CN1CCN(NC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)CC1 nan
7693269 31275 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 1 1 4.1 O=C(c1cc2cc(Br)ccc2[nH]1)N1CCc2ccccc21 nan
CHEMBL1401345 31275 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 1 1 4.1 O=C(c1cc2cc(Br)ccc2[nH]1)N1CCc2ccccc21 nan
1842681 32624 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 0 8 1.2 CCOC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1412841 32624 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 0 8 1.2 CCOC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
3159273 32812 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 5 3.0 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCCN(C)C)CC2 nan
CHEMBL1414335 32812 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 5 3.0 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCCN(C)C)CC2 nan
773430 32928 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 O=C(O)c1ccc2nc3c(nc2c1)-c1ccccc1C3=O nan
CHEMBL1415344 32928 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 O=C(O)c1ccc2nc3c(nc2c1)-c1ccccc1C3=O nan
1172271 33225 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 0 9 0.1 CCCn1c(SCC(=O)N2CCN(CC)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1417950 33225 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 0 9 0.1 CCCn1c(SCC(=O)N2CCN(CC)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
20957513 33394 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 12 2 8 2.6 CSc1ccc(CCNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1419386 33394 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 12 2 8 2.6 CSc1ccc(CCNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
656126 34347 None 3 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 4.1 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(C)c2C#N)sc(C(C)=O)c1C nan
CHEMBL1427319 34347 None 3 Human Functional pPotency = 4.8 4.8 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 4.1 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(C)c2C#N)sc(C(C)=O)c1C nan
24792443 34423 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 5 3.1 CCc1nc(SCC(=O)NNC(=O)c2ccc(C)cc2)c2ccccc2n1 nan
CHEMBL1428040 34423 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 5 3.1 CCc1nc(SCC(=O)NNC(=O)c2ccc(C)cc2)c2ccccc2n1 nan
5295519 35124 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 10 0.1 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c1cc(=O)n(C)c(=O)n1C nan
CHEMBL1434105 35124 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 10 0.1 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c1cc(=O)n(C)c(=O)n1C nan
16959503 35208 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 9 2.5 CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
CHEMBL1435220 35208 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 9 2.5 CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
2448286 35231 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 11 1.6 Cn1c(N)c(C(=O)CSc2nn(-c3ccccc3)c(=S)s2)c(=O)n(C)c1=O nan
CHEMBL1435449 35231 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 11 1.6 Cn1c(N)c(C(=O)CSc2nn(-c3ccccc3)c(=S)s2)c(=O)n(C)c1=O nan
16018790 35356 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.6 CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2F)c2cc3occc3n12 nan
CHEMBL1437127 35356 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.6 CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2F)c2cc3occc3n12 nan
135401612 35618 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 3 7 1.5 Nc1cc(O)nc(SCC(=O)Nc2cccnc2Cl)n1 nan
CHEMBL1439558 35618 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 3 7 1.5 Nc1cc(O)nc(SCC(=O)Nc2cccnc2Cl)n1 nan
15990899 35728 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 9 1 10 5.2 COc1cc2nc(SCC(=O)Nc3cccc(C)c3)n3nc(CCn4c(C)nc5ccccc54)nc3c2cc1OC nan
CHEMBL1440596 35728 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 9 1 10 5.2 COc1cc2nc(SCC(=O)Nc3cccc(C)c3)n3nc(CCn4c(C)nc5ccccc54)nc3c2cc1OC nan
16034663 35753 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3)nnc12 nan
CHEMBL1440811 35753 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3)nnc12 nan
5898351 35924 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 6 4.2 Cc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
CHEMBL1442346 35924 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 6 4.2 Cc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
986518 35983 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 4 3.3 Cc1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2ccc(Cl)cc12 nan
CHEMBL1442810 35983 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 4 3.3 Cc1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2ccc(Cl)cc12 nan
16009462 35992 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.6 CC(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
CHEMBL1442959 35992 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.6 CC(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
7245567 36017 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1ccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1443187 36017 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1ccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
4920871 36406 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 7 1.9 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NCC1CCCO1 nan
CHEMBL1446831 36406 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 7 1.9 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NCC1CCCO1 nan
139030 36429 None 20 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 196 0 1 2 2.9 O=C1C=C(O)c2cccc3cccc1c23 nan
CHEMBL1446983 36429 None 20 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 196 0 1 2 2.9 O=C1C=C(O)c2cccc3cccc1c23 nan
771978 36440 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 6 1.2 O=C(Nc1ncccn1)c1ccc([N+](=O)[O-])o1 nan
CHEMBL1447058 36440 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 6 1.2 O=C(Nc1ncccn1)c1ccc([N+](=O)[O-])o1 nan
1511203 36518 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 2 7 2.6 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NC(C)(C)CO nan
CHEMBL1447724 36518 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 2 7 2.6 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NC(C)(C)CO nan
5310565 36918 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 8 1.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)N1CCOCC1 nan
CHEMBL1450965 36918 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 8 1.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)N1CCOCC1 nan
16457956 37036 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 4 8 1.1 CCN(CC)S(=O)(=O)c1cccc(C(=O)NNC(=O)c2ccc3nc(O)c(O)nc3c2)c1 nan
CHEMBL1451892 37036 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 4 8 1.1 CCN(CC)S(=O)(=O)c1cccc(C(=O)NNC(=O)c2ccc3nc(O)c(O)nc3c2)c1 nan
2173828 37628 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 3 5.6 CCN(CC)c1nc(-c2ccccc2Cl)c2cc(Br)ccc2n1 nan
CHEMBL1456908 37628 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 3 5.6 CCN(CC)c1nc(-c2ccccc2Cl)c2cc(Br)ccc2n1 nan
20904573 37935 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 1 8 2.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCN(Cc4ccccc4)CC3)nnc12 nan
CHEMBL1459467 37935 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 1 8 2.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCN(Cc4ccccc4)CC3)nnc12 nan
734076 37964 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 4 1 4 2.4 CCCC(=O)Nc1nc(C)c(C(C)=O)s1 nan
CHEMBL1459745 37964 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 4 1 4 2.4 CCCC(=O)Nc1nc(C)c(C(C)=O)s1 nan
1511643 37965 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 8 1.3 Cc1cc([N+](=O)[O-])nn1CC(=O)Nc1cccc2nonc12 nan
CHEMBL1459750 37965 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 8 1.3 Cc1cc([N+](=O)[O-])nn1CC(=O)Nc1cccc2nonc12 nan
1838806 38095 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 7 3.6 CCOc1cccc(Nc2cc3n(c(=O)n2)CCc2cc(OC)c(OC)cc2-3)c1 nan
CHEMBL1460751 38095 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 7 3.6 CCOc1cccc(Nc2cc3n(c(=O)n2)CCc2cc(OC)c(OC)cc2-3)c1 nan
16188836 38320 None 1 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 0 4 4.0 CC1=NOC(=O)/C1=C\c1ccc(-c2ccccc2Br)o1 nan
CHEMBL1462764 38320 None 1 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 0 4 4.0 CC1=NOC(=O)/C1=C\c1ccc(-c2ccccc2Br)o1 nan
3332154 38660 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 8 3.2 Cc1nc(N)sc1N=Nc1c(C)n(C)n(-c2ccccc2)c1=O nan
CHEMBL1465412 38660 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 8 3.2 Cc1nc(N)sc1N=Nc1c(C)n(C)n(-c2ccccc2)c1=O nan
20957223 38767 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 8 2.0 Cc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1466244 38767 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 8 2.0 Cc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
2350819 38773 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.3 Cc1cc(Br)ccc1SCC(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
CHEMBL1466307 38773 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.3 Cc1cc(Br)ccc1SCC(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
7190691 39114 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 8 3.1 CC(=O)c1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1469069 39114 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 8 3.1 CC(=O)c1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
1179824 39294 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 2 7 3.6 CCOC(=O)c1sc2ncnc(Nc3cccc(C(=O)O)c3)c2c1C nan
CHEMBL1470707 39294 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 2 7 3.6 CCOC(=O)c1sc2ncnc(Nc3cccc(C(=O)O)c3)c2c1C nan
7207497 39309 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 5 4.2 Cc1c(Cl)cccc1NC(=O)CSc1ccc(-c2cccnc2)nn1 nan
CHEMBL1470773 39309 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 5 4.2 Cc1c(Cl)cccc1NC(=O)CSc1ccc(-c2cccnc2)nn1 nan
16012892 39523 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 7 2.9 CCNC(=O)c1c(NC(=O)c2nc(S(=O)(=O)CC)ncc2Cl)sc2c1CCCC2 nan
CHEMBL1472696 39523 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 7 2.9 CCNC(=O)c1c(NC(=O)c2nc(S(=O)(=O)CC)ncc2Cl)sc2c1CCCC2 nan
16030433 39667 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 1 6 5.0 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)c1OC nan
CHEMBL1474670 39667 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 1 6 5.0 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)c1OC nan
4547893 39844 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 6 3.3 COc1ccccc1C(=O)Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1 nan
CHEMBL1477066 39844 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 6 3.3 COc1ccccc1C(=O)Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1 nan
1313916 40109 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1479446 40109 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
16021977 40477 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 6 4.5 CCOC(=O)c1ccc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2-n2cccc2)cc1 nan
CHEMBL1482573 40477 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 6 4.5 CCOC(=O)c1ccc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2-n2cccc2)cc1 nan
16025700 40696 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1cccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
CHEMBL1484349 40696 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1cccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
4969640 40727 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 1.5 COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1nncs1 nan
CHEMBL1484709 40727 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 1.5 COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1nncs1 nan
2267309 41232 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.8 Cc1cc(N)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
CHEMBL1488814 41232 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.8 Cc1cc(N)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
3157588 41502 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 3.7 CC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccccc1 nan
CHEMBL1490855 41502 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 3.7 CC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccccc1 nan
3755909 42088 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2ccc(Br)s2)nc(-n2cccc2)n1 nan
CHEMBL1495948 42088 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2ccc(Br)s2)nc(-n2cccc2)n1 nan
6501461 42707 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 9 2.7 CCC(Sc1nnc(-c2ccco2)n1C)C(=O)Nc1nnc(C)s1 nan
CHEMBL1501425 42707 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 9 2.7 CCC(Sc1nnc(-c2ccco2)n1C)C(=O)Nc1nnc(C)s1 nan
20968950 42757 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 0.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCC(C(N)=O)CC1)C(=O)CO2 nan
CHEMBL1501847 42757 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 0.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCC(C(N)=O)CC1)C(=O)CO2 nan
7692847 42898 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 6 3.1 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc2c(c1)OCO2 nan
CHEMBL1503072 42898 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 6 3.1 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc2c(c1)OCO2 nan
1243282 43016 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 2 1 5 4.6 Fc1ccc(-n2c(S)nnc2-c2ccc3ccccc3n2)cc1Cl nan
CHEMBL1504174 43016 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 2 1 5 4.6 Fc1ccc(-n2c(S)nnc2-c2ccc3ccccc3n2)cc1Cl nan
20888797 43237 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 9 1.5 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCN(CCO)CC2)s1 nan
CHEMBL1506053 43237 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 9 1.5 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCN(CCO)CC2)s1 nan
3965652 43259 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 5 3.6 Oc1nc(S)ncc1Oc1ccc(Cl)cc1Cl nan
CHEMBL1506226 43259 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 5 3.6 Oc1nc(S)ncc1Oc1ccc(Cl)cc1Cl nan
664243 43498 None 8 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.7 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)no1 nan
CHEMBL1508235 43498 None 8 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.7 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)no1 nan
1564171 43580 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 8 3.9 C=CCn1c(SCC(=O)Nc2sccc2C#N)nc2sc(C)c(C)c2c1=O nan
CHEMBL1509018 43580 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 8 3.9 C=CCn1c(SCC(=O)Nc2sccc2C#N)nc2sc(C)c(C)c2c1=O nan
660816 43744 None 42 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 5 3.2 COc1ccccc1-c1nnc(S)n1-c1ccccc1 nan
CHEMBL1510509 43744 None 42 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 5 3.2 COc1ccccc1-c1nnc(S)n1-c1ccccc1 nan
4736989 43903 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 7 1.4 O=C(O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1511802 43903 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 7 1.4 O=C(O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
16407031 43921 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 9 1 9 3.2 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCCN4CCOCC4)cc3c3ccnc2c31 nan
CHEMBL1512174 43921 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 9 1 9 3.2 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCCN4CCOCC4)cc3c3ccnc2c31 nan
16021393 43928 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 4 6.6 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(C(F)(F)F)c4)cc(C)c3c2)c1 nan
CHEMBL1512269 43928 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 4 6.6 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(C(F)(F)F)c4)cc(C)c3c2)c1 nan
16018932 44073 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 0 7 6.7 CCc1nnc(SCc2nc(-c3cccc(Cl)c3)oc2C)c2cc3sc(C)cc3n12 nan
CHEMBL1514500 44073 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 0 7 6.7 CCc1nnc(SCc2nc(-c3cccc(Cl)c3)oc2C)c2cc3sc(C)cc3n12 nan
20885685 44140 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccccc1CNC(=O)CCCn1nc(C)n2ccnc2c1=O nan
CHEMBL1515364 44140 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccccc1CNC(=O)CCCn1nc(C)n2ccnc2c1=O nan
16018754 44167 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 8 3.8 COc1cc(NC(=O)CSc2nnc(C)n3c2cc2oc(C)cc23)cc(OC)c1 nan
CHEMBL1515810 44167 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 8 3.8 COc1cc(NC(=O)CSc2nnc(C)n3c2cc2oc(C)cc23)cc(OC)c1 nan
4350514 45225 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 1.9 Cc1nc2ccccc2c(=O)n1NC(=O)Cc1ccc([N+](=O)[O-])cc1 nan
CHEMBL1525803 45225 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 1.9 Cc1nc2ccccc2c(=O)n1NC(=O)Cc1ccc([N+](=O)[O-])cc1 nan
135455188 45535 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 9 3.3 N#Cc1c(O)nc(SCC(=O)Nc2nnc(C(F)(F)F)s2)nc1-c1ccccc1 nan
CHEMBL1528492 45535 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 9 3.3 N#Cc1c(O)nc(SCC(=O)Nc2nnc(C(F)(F)F)s2)nc1-c1ccccc1 nan
3535143 45699 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 9 3.6 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4ccccc4n3)nc3ccsc3c2=O)CC1 nan
CHEMBL1529863 45699 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 9 3.6 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4ccccc4n3)nc3ccsc3c2=O)CC1 nan
16030435 45722 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 4 5.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccccc2Cl)cc1 nan
CHEMBL1530187 45722 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 4 5.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccccc2Cl)cc1 nan
54677747 45989 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 1 2 7 4.6 O=c1oc2ccccc2c(O)c1[C@H]1c2ccc(O)cc2Oc2c1c(=O)oc1ccccc21 nan
CHEMBL1532491 45989 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 1 2 7 4.6 O=c1oc2ccccc2c(O)c1[C@H]1c2ccc(O)cc2Oc2c1c(=O)oc1ccccc21 nan
6498569 46023 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 7 2 5 1.0 Cc1ccc(OCC(=O)NCCNC(=O)c2cnccn2)cc1C nan
CHEMBL1532759 46023 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 7 2 5 1.0 Cc1ccc(OCC(=O)NCCNC(=O)c2cnccn2)cc1C nan
6060971 46027 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 8 1 6 3.4 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2c2ccccc2)cc1 nan
CHEMBL1532782 46027 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 8 1 6 3.4 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2c2ccccc2)cc1 nan
3262927 46348 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 1.3 O=C(OCN1C(=O)c2ccccc2C1=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1F nan
CHEMBL1535967 46348 None 0 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 1.3 O=C(OCN1C(=O)c2ccccc2C1=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1F nan
6018171 46350 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 6 3.9 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1 nan
CHEMBL1535987 46350 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 6 3.9 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1 nan
7120055 46412 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 4.4 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1C nan
CHEMBL1536665 46412 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 4.4 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1C nan
2086676 46482 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 8 1.3 Cn1c(=O)c(C(=O)COc2ccc(C#N)cc2)c(N)n(Cc2ccccc2)c1=O nan
CHEMBL1537193 46482 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 8 1.3 Cn1c(=O)c(C(=O)COc2ccc(C#N)cc2)c(N)n(Cc2ccccc2)c1=O nan
20888841 46514 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 0 8 2.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CC)CC2)s1 nan
CHEMBL1537517 46514 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 0 8 2.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CC)CC2)s1 nan
22334156 46733 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 6 1 9 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1OC nan
CHEMBL1539318 46733 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 6 1 9 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1OC nan
3151316 46736 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1539382 46736 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CC4CCCO4)c3nc12 nan
17581317 46954 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 1 5 3.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc(Br)o1 nan
CHEMBL1541200 46954 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 1 5 3.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc(Br)o1 nan
6228228 47068 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 7 4.0 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2)s1 nan
CHEMBL1542130 47068 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 7 4.0 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2)s1 nan
2359872 47097 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 4 2.8 O=C(CSc1cnc2ccccc2n1)NC1CCCC1 nan
CHEMBL1542457 47097 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 4 2.8 O=C(CSc1cnc2ccccc2n1)NC1CCCC1 nan
2346972 47116 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 10 -1.0 CN(C)S(=O)(=O)c1cccc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
CHEMBL1542615 47116 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 10 -1.0 CN(C)S(=O)(=O)c1cccc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
135420430 47121 None 8 Human Functional pPotency = 4.8 4.8 -4 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 8 3.5 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1cc(C)on1 nan
CHEMBL1542646 47121 None 8 Human Functional pPotency = 4.8 4.8 -4 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 8 3.5 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1cc(C)on1 nan
1866349 47457 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
661670 47457 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1406059 47457 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1545185 47457 None 8 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
4876432 47482 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 2 6 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
CHEMBL1545378 47482 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 2 6 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
2595072 47483 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 6 1 4 3.1 O=C(CSc1ncnc2ccccc12)NCCc1ccccc1 nan
CHEMBL1545386 47483 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 6 1 4 3.1 O=C(CSc1ncnc2ccccc12)NCCc1ccccc1 nan
2115012 47550 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 10 0.2 CCCn1c(N)c(C(=O)COC(=O)c2c(C)noc2C)c(=O)n(C)c1=O nan
CHEMBL1545973 47550 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 10 0.2 CCCn1c(N)c(C(=O)COC(=O)c2c(C)noc2C)c(=O)n(C)c1=O nan
241512 47853 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 1 2 2 3.2 c1ccc(-c2ccc3c(c2)NCCN3)cc1 nan
CHEMBL1548782 47853 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 1 2 2 3.2 c1ccc(-c2ccc3c(c2)NCCN3)cc1 nan
16189384 48072 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 573 10 2 9 1.4 CSCCC(NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C)C(=O)NC1CCN(Cc2ccccc2)CC1 nan
CHEMBL1550614 48072 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 573 10 2 9 1.4 CSCCC(NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C)C(=O)NC1CCN(Cc2ccccc2)CC1 nan
16019521 48144 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 9 2.5 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCN(C)CC2)c2sccc23)c1 nan
CHEMBL1551283 48144 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 9 2.5 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCN(C)CC2)c2sccc23)c1 nan
6414933 48176 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 4.2 CCOC(=O)c1ccc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)cc1 nan
CHEMBL1551836 48176 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 4.2 CCOC(=O)c1ccc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)cc1 nan
16018808 48188 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 8 1 7 2.7 CCc1nnc(SC(CC)C(=O)NCCOC)c2cc3occc3n12 nan
CHEMBL1551969 48188 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 8 1 7 2.7 CCc1nnc(SC(CC)C(=O)NCCOC)c2cc3occc3n12 nan
5301786 48212 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 1 8 1.0 Cc1ccc(-c2c(C)n3c4c(=O)n(C)c(=O)n(C)c4nc3n2CCO)cc1 nan
CHEMBL1552221 48212 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 1 8 1.0 Cc1ccc(-c2c(C)n3c4c(=O)n(C)c(=O)n(C)c4nc3n2CCO)cc1 nan
1622536 48275 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 4.7 CCCCOC(=O)c1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 nan
CHEMBL1553105 48275 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 4.7 CCCCOC(=O)c1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 nan
16020969 48311 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 5.0 Cc1oc(-c2cccc(Br)c2)nc1CSc1nc2cccnc2[nH]1 nan
CHEMBL1553552 48311 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 5.0 Cc1oc(-c2cccc(Br)c2)nc1CSc1nc2cccnc2[nH]1 nan
4291583 48346 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 14 4 8 2.2 CSCCC(NS(=O)(=O)c1ccc2c(c1)Cc1cc(S(=O)(=O)NC(CCSC)C(=O)O)ccc1-2)C(=O)O nan
CHEMBL1554139 48346 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 14 4 8 2.2 CSCCC(NS(=O)(=O)c1ccc2c(c1)Cc1cc(S(=O)(=O)NC(CCSC)C(=O)O)ccc1-2)C(=O)O nan
20877874 48385 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 0 4 3.5 CCCN1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
CHEMBL1554696 48385 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 0 4 3.5 CCCN1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
16011310 48452 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 5 5.5 CCc1nnc(SCc2cccc(Cl)c2)c2cc3sccc3n12 nan
CHEMBL1555647 48452 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 5 5.5 CCc1nnc(SCc2cccc(Cl)c2)c2cc3sccc3n12 nan
16030467 48980 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 4 5.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)NCc1ccccc1Cl nan
CHEMBL1560326 48980 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 4 5.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)NCc1ccccc1Cl nan
2415608 49032 None 22 Human Functional pPotency = 4.8 4.8 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 2 7 2.8 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3cc4c(cc3nc2Cl)OCCO4)cc1 nan
CHEMBL1560923 49032 None 22 Human Functional pPotency = 4.8 4.8 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 2 7 2.8 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3cc4c(cc3nc2Cl)OCCO4)cc1 nan
15988392 49258 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.8 CCn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
CHEMBL1562908 49258 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.8 CCn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
3805026 49371 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Cl)cc2)no1 nan
CHEMBL1563863 49371 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Cl)cc2)no1 nan
6228410 49434 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 7 4.1 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2F)s1 nan
CHEMBL1564525 49434 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 7 4.1 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2F)s1 nan
4802105 49603 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 2.8 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCCC2)ccc1Cl nan
CHEMBL1565823 49603 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 2.8 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCCC2)ccc1Cl nan
225436 49850 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 198 0 1 3 1.2 O=C1c2ccccc2C(=O)c2[nH]cnc21 nan
CHEMBL1567800 49850 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 198 0 1 3 1.2 O=C1c2ccccc2C(=O)c2[nH]cnc21 nan
2054020 49960 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 7 4.7 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nc2ccccc2s1 nan
CHEMBL1568611 49960 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 7 4.7 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nc2ccccc2s1 nan
2883018 50123 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 0 1 5 1.6 N#Cc1c2n(c3c(N)ncnc13)CCCCC2 nan
CHEMBL1570092 50123 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 0 1 5 1.6 N#Cc1c2n(c3c(N)ncnc13)CCCCC2 nan
16018256 50257 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 CCOc1ccc(CCNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)cc1OCC nan
CHEMBL1571269 50257 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 CCOc1ccc(CCNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)cc1OCC nan
25163648 50391 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 4 4.3 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1c(F)cccc1Cl nan
CHEMBL1572593 50391 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 4 4.3 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1c(F)cccc1Cl nan
20957176 50470 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 0 9 0.2 CN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
CHEMBL1573164 50470 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 0 9 0.2 CN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
4200979 50796 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 7 1.0 COC(=O)CCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
CHEMBL1576536 50796 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 7 1.0 COC(=O)CCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
1132498 51008 None 7 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 5 5.1 Cc1ccc2nsnc2c1NC(=O)c1sc2ccccc2c1Cl nan
CHEMBL1578314 51008 None 7 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 5 5.1 Cc1ccc2nsnc2c1NC(=O)c1sc2ccccc2c1Cl nan
3220367 51264 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 1 6 2.4 COCCNC(=O)C(OC(=O)c1nsc(Cl)c1Cl)C(C)C nan
CHEMBL1580567 51264 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 1 6 2.4 COCCNC(=O)C(OC(=O)c1nsc(Cl)c1Cl)C(C)C nan
4343313 51464 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.2 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)n1 nan
CHEMBL1582134 51464 None 12 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.2 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)n1 nan
3338549 51480 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1582307 51480 None 10 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
20917770 51636 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 7 2.4 CN(Cc1ccco1)S(=O)(=O)c1ccc(CN2C(=O)c3cccnc3C2=O)s1 nan
CHEMBL1583626 51636 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 7 2.4 CN(Cc1ccco1)S(=O)(=O)c1ccc(CN2C(=O)c3cccnc3C2=O)s1 nan
18562929 51785 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 9 1.1 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCOCC4)nn23)cc1 nan
CHEMBL1584882 51785 None 9 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 9 1.1 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCOCC4)nn23)cc1 nan
2427540 52209 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 10 1.4 Cn1c(N)c(C(=O)CSc2nc3ccccc3c(=O)n2Cc2ccccc2)c(=O)n(C)c1=O nan
CHEMBL1588321 52209 None 2 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 10 1.4 Cn1c(N)c(C(=O)CSc2nc3ccccc3c(=O)n2Cc2ccccc2)c(=O)n(C)c1=O nan
20923114 52234 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 9 0 6 2.7 CCCN(CCC)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1588547 52234 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 9 0 6 2.7 CCCN(CCC)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
20885679 52438 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 1.9 Cc1nn(CCCC(=O)NCc2ccccc2Cl)c(=O)c2nccn12 nan
CHEMBL1590561 52438 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 1.9 Cc1nn(CCCC(=O)NCc2ccccc2Cl)c(=O)c2nccn12 nan
16023172 52462 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 3.4 CCCCNC(=O)CSc1nnc(C)c2c(C)n(-c3ccccc3)nc12 nan
CHEMBL1590852 52462 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 3.4 CCCCNC(=O)CSc1nnc(C)c2c(C)n(-c3ccccc3)nc12 nan
16016417 52503 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 3.4 Cc1cc(O)c(CN2CCN(c3ccccc3)CC2)c2oc(=O)cc(C)c12 nan
CHEMBL1591358 52503 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 3.4 Cc1cc(O)c(CN2CCN(c3ccccc3)CC2)c2oc(=O)cc(C)c12 nan
16009611 52661 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1cccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c1)c1ccc(F)cc1 nan
CHEMBL1593455 52661 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1cccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c1)c1ccc(F)cc1 nan
16453157 53119 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 8 2.7 O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1nn(-c2ccccc2)ccc1=O nan
CHEMBL1597782 53119 None 11 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 8 2.7 O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1nn(-c2ccccc2)ccc1=O nan
15990388 53326 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.4 Cc1c(NC(=O)c2nc3ccccc3n(C)c2=O)cccc1[N+](=O)[O-] nan
CHEMBL1599627 53326 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.4 Cc1c(NC(=O)c2nc3ccccc3n(C)c2=O)cccc1[N+](=O)[O-] nan
20917744 53405 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 7 2.3 Cc1ccc(CNS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)s2)o1 nan
CHEMBL1600418 53405 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 7 2.3 Cc1ccc(CNS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)s2)o1 nan
3252667 53421 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 4.8 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1600566 53421 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 4.8 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
5389427 53501 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 1 7 4.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3cc(C)on3)C2c2ccccc2OC)cc1 nan
CHEMBL1601252 53501 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 1 7 4.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3cc(C)on3)C2c2ccccc2OC)cc1 nan
723168 53827 None 31 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 4 1 4 4.2 O=C(O)Cc1sc(-c2ccccc2)nc1-c1cccs1 nan
CHEMBL1604196 53827 None 31 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 4 1 4 4.2 O=C(O)Cc1sc(-c2ccccc2)nc1-c1cccs1 nan
2235547 53966 None 25 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 3 1 5 2.4 CCOc1ccccc1-c1nnc(S)o1 nan
CHEMBL1605444 53966 None 25 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 3 1 5 2.4 CCOc1ccccc1-c1nnc(S)o1 nan
2927721 54116 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 2 7 2.6 CCOCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1606632 54116 None 15 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 2 7 2.6 CCOCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
3417563 54206 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3983329 54206 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1607267 54206 None 14 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3146573 54431 None 16 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 7 3.5 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1609156 54431 None 16 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 7 3.5 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
1941998 54464 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4F)sc3n2)c1 nan
CHEMBL1609358 54464 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4F)sc3n2)c1 nan
5389862 54596 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 6 3.5 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
CHEMBL1610515 54596 None 4 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 6 3.5 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
9550945 54759 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 2 0 5 3.2 CCOC(=O)N1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
CHEMBL1611989 54759 None 4 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 2 0 5 3.2 CCOC(=O)N1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
2120111 55719 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
CHEMBL1484562 55719 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
CHEMBL1622008 55719 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
1724830 55865 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
CHEMBL1520781 55865 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
CHEMBL1623209 55865 None 3 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
9619025 71993 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 10 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1OC nan
CHEMBL1973418 71993 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 10 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1OC nan
5065598 72611 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 0 8 2.9 CCOC(=O)Cn1/c(=N/C(=O)c2cccs2)sc2cc(C(=O)OC)ccc21 nan
CHEMBL1992834 72611 None 9 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 0 8 2.9 CCOC(=O)Cn1/c(=N/C(=O)c2cccs2)sc2cc(C(=O)OC)ccc21 nan
5286961 72862 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
9915251 72862 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL2001904 72862 None 6 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
95028 93861 None 21 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 2 0 6 0.5 Cn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O nan
CHEMBL24759 93861 None 21 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 2 0 6 0.5 Cn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O nan
135723776 107640 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 2 5 2.6 Cc1cc(O)nc(N/N=C/c2c(F)c(F)c(F)c(F)c2F)n1 nan
CHEMBL3189383 107640 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 2 5 2.6 Cc1cc(O)nc(N/N=C/c2c(F)c(F)c(F)c(F)c2F)n1 nan
5342833 107650 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 3 9 -2.3 Cn1c(=O)c2nc(N/N=C(/C#N)C(N)=O)[nH]c2n(C)c1=O nan
CHEMBL3189560 107650 None 7 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 3 9 -2.3 Cn1c(=O)c2nc(N/N=C(/C#N)C(N)=O)[nH]c2n(C)c1=O nan
4564145 107903 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(Br)cc2)n(C)c1C nan
CHEMBL3192424 107903 None 8 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(Br)cc2)n(C)c1C nan
135526880 108323 None 5 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
135643494 108323 None 5 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
137199718 108323 None 5 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
CHEMBL3197292 108323 None 5 Human Functional pPotency = 4.8 4.8 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
9660607 108349 None 4 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 3 3.8 Cc1ccc(N2C(=O)CS/C2=N\C(=S)Nc2ccccc2)cc1 nan
CHEMBL3197507 108349 None 4 Human Functional pPotency = 4.8 4.8 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 3 3.8 Cc1ccc(N2C(=O)CS/C2=N\C(=S)Nc2ccccc2)cc1 nan
9583775 108950 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 2 7 2.1 Nc1c(C(=O)N/N=C/c2ccc([N+](=O)[O-])cc2)cnn1-c1ccccc1 nan
CHEMBL3210811 108950 None 1 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 2 7 2.1 Nc1c(C(=O)N/N=C/c2ccc([N+](=O)[O-])cc2)cnn1-c1ccccc1 nan
3669734 201177 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 2.6 CCOC(=O)N1CCN(C(=O)CCCCn2c(=S)[nH]c3ccsc3c2=O)CC1 nan
CHEMBL582737 201177 None 5 Human Functional pPotency = 4.8 4.8 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 2.6 CCOC(=O)N1CCN(C(=O)CCCCn2c(=S)[nH]c3ccsc3c2=O)CC1 nan
3324 208896 None 69 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 7 1 9 0.5 CC(=O)OCC(CCn1cnc2cnc(N)nc21)COC(C)=O nan
CHEMBL880 208896 None 69 Human Functional pPotency = 4.8 4.8 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 7 1 9 0.5 CC(=O)OCC(CCn1cnc2cnc(N)nc21)COC(C)=O nan
1028 291 None 40 Human Functional pPotency = 4.7 4.7 -1096 19
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
139148732 291 None 40 Human Functional pPotency = 4.7 4.7 -1096 19
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
479 291 None 40 Human Functional pPotency = 4.7 4.7 -1096 19
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
5816 291 None 40 Human Functional pPotency = 4.7 4.7 -1096 19
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
5816.0 291 None 40 Human Functional pPotency = 4.7 4.7 -1096 19
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
CHEMBL679 291 None 40 Human Functional pPotency = 4.7 4.7 -1096 19
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
DB00668 291 None 40 Human Functional pPotency = 4.7 4.7 -1096 19
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
3289443 7067 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 5 5.0 Nc1c(C(=O)Nc2cccc(F)c2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1084955 7067 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 5 5.0 Nc1c(C(=O)Nc2cccc(F)c2)sc2nc(-c3cccs3)ccc12 nan
4112670 10483 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 3 4 5.5 O=C(NCCc1ccc(Cl)cc1)C1CCC(CNc2nc(=S)[nH]c3ccccc23)CC1 nan
CHEMBL1165197 10483 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 3 4 5.5 O=C(NCCc1ccc(Cl)cc1)C1CCC(CNc2nc(=S)[nH]c3ccccc23)CC1 nan
1003890 18368 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)c1 nan
CHEMBL1271075 18368 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)c1 nan
790786 19776 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 1 4.5 CCc1c(C)nc2ccc(Br)cc2c1Cl nan
CHEMBL1301385 19776 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 1 4.5 CCc1c(C)nc2ccc(Br)cc2c1Cl nan
6621843 19865 None 0 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 1 5 2.4 CCCNc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1302226 19865 None 0 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 1 5 2.4 CCCNc1nc2ccccc2n2c(C)nnc12 nan
926200 20089 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 4 4.0 Fc1cnc(N2CCc3ccccc32)nc1N1CCc2ccccc21 nan
CHEMBL1303908 20089 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 4 4.0 Fc1cnc(N2CCc3ccccc32)nc1N1CCc2ccccc21 nan
20881176 20377 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 1 7 2.3 CC(C)CCn1c(=O)c2ccccc2n2c(CCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1306246 20377 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 1 7 2.3 CC(C)CCn1c(=O)c2ccccc2n2c(CCC(=O)NCC3CCCO3)nnc12 nan
2220688 20528 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 0 6 4.3 Cc1ccc(-c2cc(C(=O)N3CCN(c4ncccn4)CC3)c3cc(Br)ccc3n2)o1 nan
CHEMBL1307526 20528 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 0 6 4.3 Cc1ccc(-c2cc(C(=O)N3CCN(c4ncccn4)CC3)c3cc(Br)ccc3n2)o1 nan
2962628 20619 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 5 5.0 CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2C(=O)c2ccccc2)c(Br)cc1OCC(=O)O nan
CHEMBL1308267 20619 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 5 5.0 CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2C(=O)c2ccccc2)c(Br)cc1OCC(=O)O nan
3774396 20837 None 1 Human Functional pPotency = 4.7 4.7 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 1 3 6 1.7 CSc1nc(S)c2[nH]c(S)nc2n1 nan
CHEMBL1310138 20837 None 1 Human Functional pPotency = 4.7 4.7 -2 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 1 3 6 1.7 CSc1nc(S)c2[nH]c(S)nc2n1 nan
6247103 21150 None 17 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 4.4 COc1cc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc(OC)c1OC nan
CHEMBL1312514 21150 None 17 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 4.4 COc1cc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc(OC)c1OC nan
2927414 21507 None 18 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 8 1.9 CCOCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1315953 21507 None 18 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 8 1.9 CCOCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
16187669 21855 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 11 2 7 3.0 CCC1CCCCN1CCCNC(=O)CCCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
CHEMBL1319736 21855 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 11 2 7 3.0 CCC1CCCCN1CCCNC(=O)CCCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
1473386 21963 None 18 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 7 0.7 CCOC(=O)CSc1nc(=O)n2ccccc2n1 nan
CHEMBL1320637 21963 None 18 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 7 0.7 CCOC(=O)CSc1nc(=O)n2ccccc2n1 nan
2363935 22004 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 1 8 0.0 Cn1c(N)c(C(=O)COC(=O)CCc2ccccc2)c(=O)n(C)c1=O nan
CHEMBL1321001 22004 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 1 8 0.0 Cn1c(N)c(C(=O)COC(=O)CCc2ccccc2)c(=O)n(C)c1=O nan
1485315 22021 None 18 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 5 1.6 CS(=O)(=O)NNC(=O)c1cc2cc3ccccc3nc2s1 nan
CHEMBL1321144 22021 None 18 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 5 1.6 CS(=O)(=O)NNC(=O)c1cc2cc3ccccc3nc2s1 nan
20903731 22040 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 9 1 7 2.2 CC1CCN(c2ccc3nnc(CCC(=O)NCCCOC(C)C)n3n2)CC1 nan
CHEMBL1321331 22040 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 9 1 7 2.2 CC1CCN(c2ccc3nnc(CCC(=O)NCCCOC(C)C)n3n2)CC1 nan
16014625 22072 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.3 CC(=O)Nc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)cc1 nan
CHEMBL1321666 22072 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.3 CC(=O)Nc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)cc1 nan
16031994 22247 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 6 5.3 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nn2)s1 nan
CHEMBL1323264 22247 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 6 5.3 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nn2)s1 nan
857564 22304 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cccc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1323763 22304 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cccc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
1955570 22405 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccccc4C)sc3n2)c1 nan
CHEMBL1324540 22405 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccccc4C)sc3n2)c1 nan
16019112 22429 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 1 8 3.6 Cc1ccccc1NC(=O)Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
CHEMBL1324746 22429 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 1 8 3.6 Cc1ccccc1NC(=O)Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
20957487 22507 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1 nan
CHEMBL1325415 22507 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1 nan
654648 22539 None 10 Human Functional pPotency = 4.7 4.7 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.4 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
CHEMBL1325819 22539 None 10 Human Functional pPotency = 4.7 4.7 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.4 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
16411657 22694 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 4 0.9 CC1=NN(c2ccccc2)C(=O)C1/C=C1/NC(=S)NC1=O nan
CHEMBL1327209 22694 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 4 0.9 CC1=NN(c2ccccc2)C(=O)C1/C=C1/NC(=S)NC1=O nan
3725176 22917 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3cccc(C)c3)n2)cc1 nan
CHEMBL1329088 22917 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3cccc(C)c3)n2)cc1 nan
2965680 23820 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 4 4.4 CC(NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12)C1CCCO1 nan
CHEMBL1336138 23820 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 4 4.4 CC(NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12)C1CCCO1 nan
2928436 23849 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 2 8 1.7 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1Cc1ccco1 nan
CHEMBL1336360 23849 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 2 8 1.7 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1Cc1ccco1 nan
16023198 24074 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.0 Cc1nnc(SCC(=O)NCc2cccc(F)c2)c2nn(-c3ccccc3)c(C)c12 nan
CHEMBL1338308 24074 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.0 Cc1nnc(SCC(=O)NCc2cccc(F)c2)c2nn(-c3ccccc3)c(C)c12 nan
4907461 24192 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 5 3.7 CCCCNc1ncnc2sc3c(c12)CCN(CCC)C3 nan
CHEMBL1339392 24192 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 5 3.7 CCCCNc1ncnc2sc3c(c12)CCN(CCC)C3 nan
4173573 24637 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 2 8 0.8 Cc1cccn2c(=O)c3cc(C(N)=S)c(=N)n(CCCN4CCOCC4)c3nc12 nan
CHEMBL1343182 24637 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 2 8 0.8 Cc1cccn2c(=O)c3cc(C(N)=S)c(=N)n(CCCN4CCOCC4)c3nc12 nan
2439152 24650 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 0 5 2.2 Cc1ccc2nc(Cn3cc(C(F)(F)F)ccc3=O)cc(=O)n2c1 nan
CHEMBL1343295 24650 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 0 5 2.2 Cc1ccc2nc(Cn3cc(C(F)(F)F)ccc3=O)cc(=O)n2c1 nan
4918386 25000 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 2.5 Cc1cc(CNC(=O)C(C)n2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
CHEMBL1346435 25000 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 2.5 Cc1cc(CNC(=O)C(C)n2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
20904584 25016 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 9 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccccn4)CC3)nnc12 nan
CHEMBL1346578 25016 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 9 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccccn4)CC3)nnc12 nan
6112144 25031 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 9 1 7 3.5 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1346652 25031 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 9 1 7 3.5 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
5181544 25349 None 14 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 8 3.5 COC(=O)c1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1349309 25349 None 14 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 8 3.5 COC(=O)c1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
663780 25427 None 11 Human Functional pPotency = 4.7 4.7 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 2 8 2.2 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CCCOC(C)C)c(=O)n2c1 nan
CHEMBL1349978 25427 None 11 Human Functional pPotency = 4.7 4.7 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 2 8 2.2 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CCCOC(C)C)c(=O)n2c1 nan
860395 25436 None 35 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 3 3.8 O=C(O)c1cc(-c2cccs2)nc2ccc(F)cc12 nan
CHEMBL1350037 25436 None 35 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 3 3.8 O=C(O)c1cc(-c2cccs2)nc2ccc(F)cc12 nan
1013700 25627 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 0 3 3.6 O=C(COc1ccc2cc(Br)ccc2c1Br)N1CCOCC1 nan
CHEMBL1351652 25627 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 0 3 3.6 O=C(COc1ccc2cc(Br)ccc2c1Br)N1CCOCC1 nan
4137672 25771 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 4 4.1 O=C(O)c1ccccc1SCc1cn2cc(Br)ccc2n1 nan
CHEMBL1352828 25771 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 4 4.1 O=C(O)c1ccccc1SCc1cn2cc(Br)ccc2n1 nan
15991076 26068 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 6.6 COc1cc2ccccc2cc1C(=O)Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1 nan
CHEMBL1355303 26068 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 6.6 COc1cc2ccccc2cc1C(=O)Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1 nan
16019626 26152 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 8 3.2 Cc1ccc(-n2nnc(-c3nc(-c4cccs4)no3)c2N)c(C)c1 nan
CHEMBL1356419 26152 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 8 3.2 Cc1ccc(-n2nnc(-c3nc(-c4cccs4)no3)c2N)c(C)c1 nan
16033238 26204 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 5 5.6 Cc1cccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1C nan
CHEMBL1357134 26204 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 5 5.6 Cc1cccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1C nan
4084525 26521 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 0 6 3.9 CCOC(=O)c1sc2nc(C)nc(N3CCCCC3C)c2c1C nan
CHEMBL1360386 26521 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 0 6 3.9 CCOC(=O)c1sc2nc(C)nc(N3CCCCC3C)c2c1C nan
1130278 26551 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 4.0 Cc1ccc(NC(=O)CSc2nnc(COc3ccccc3C)o2)cc1 nan
CHEMBL1360712 26551 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 4.0 Cc1ccc(NC(=O)CSc2nnc(COc3ccccc3C)o2)cc1 nan
2112396 26993 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 7 4.0 CNS(=O)(=O)c1cccc(C(=O)OCC(=O)Nc2ccc(-c3nc4ccc(C)cc4s3)cc2)c1 nan
CHEMBL1364577 26993 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 7 4.0 CNS(=O)(=O)c1cccc(C(=O)OCC(=O)Nc2ccc(-c3nc4ccc(C)cc4s3)cc2)c1 nan
3244890 27778 None 10 Human Functional pPotency = 4.7 4.7 -5 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.7 O=C(O)CCc1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1370669 27778 None 10 Human Functional pPotency = 4.7 4.7 -5 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.7 O=C(O)CCc1ccc(-c2ccc(Br)cc2)o1 nan
135443907 28123 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 2 9 4.5 CCOc1ccc2nc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)sc2c1 nan
CHEMBL1373145 28123 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 2 9 4.5 CCOc1ccc2nc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)sc2c1 nan
16018180 28125 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(OC)c(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)c1 nan
CHEMBL1373157 28125 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(OC)c(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)c1 nan
2727621 28227 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 7 3.3 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccccc3)c(N)c12 nan
CHEMBL1373780 28227 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 7 3.3 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccccc3)c(N)c12 nan
16019289 28469 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 5 4.9 Cc1ccc(NC(=O)CSc2ccc(-c3cccs3)nn2)cc1Cl nan
CHEMBL1375486 28469 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 5 4.9 Cc1ccc(NC(=O)CSc2ccc(-c3cccs3)nn2)cc1Cl nan
2361888 28630 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc(O)c(C(=O)OCC(=O)N2CCCC2)c1 nan
CHEMBL1377052 28630 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc(O)c(C(=O)OCC(=O)N2CCCC2)c1 nan
887924 28714 None 7 Human Functional pPotency = 4.7 4.7 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 4 4.8 Cc1ccc2c(Cl)c(C(=O)Nc3ccc4c(c3)OCO4)sc2c1 nan
CHEMBL1377850 28714 None 7 Human Functional pPotency = 4.7 4.7 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 4 4.8 Cc1ccc2c(Cl)c(C(=O)Nc3ccc4c(c3)OCO4)sc2c1 nan
135527311 29203 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 8 3.7 COC(=O)CSc1nc(O)c2c(C(F)(F)F)cc(-c3cccs3)nc2n1 nan
CHEMBL1382080 29203 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 8 3.7 COC(=O)CSc1nc(O)c2c(C(F)(F)F)cc(-c3cccs3)nc2n1 nan
15987888 29468 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1384448 29468 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
54710218 29765 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 4 3.7 Cc1ccc(Sc2c(O)c3ccccc3n(C)c2=O)cc1 nan
CHEMBL1386873 29765 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 4 3.7 Cc1ccc(Sc2c(O)c3ccccc3n(C)c2=O)cc1 nan
4047539 29964 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 8 0.8 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1388441 29964 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 8 0.8 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
733870 30080 None 31 Human Functional pPotency = 4.7 4.7 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 1 4 3.6 CC(=O)c1sc(NC(=O)c2ccc(Cl)cc2)nc1C nan
CHEMBL1389324 30080 None 31 Human Functional pPotency = 4.7 4.7 -3 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 1 4 3.6 CC(=O)c1sc(NC(=O)c2ccc(Cl)cc2)nc1C nan
829950 30194 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 5 1.6 CN(C)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1390362 30194 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 5 1.6 CN(C)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
5027542 30238 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 7 1.5 O=C(CN1C(=O)C2CC=CCC2C1=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1390760 30238 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 7 1.5 O=C(CN1C(=O)C2CC=CCC2C1=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
3634961 30352 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
4315628 30352 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
CHEMBL1391748 30352 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
5898126 30384 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 4.1 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccs2)cc1 nan
CHEMBL1392030 30384 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 4.1 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccs2)cc1 nan
4531942 30421 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 11 0.0 CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
CHEMBL1392325 30421 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 11 0.0 CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
1102249 30481 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 2 4 4.5 O=C(Nc1ccc(Br)cn1)c1cccc(C(=O)Nc2ccc(Br)cn2)c1 nan
CHEMBL1392808 30481 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 2 4 4.5 O=C(Nc1ccc(Br)cn1)c1cccc(C(=O)Nc2ccc(Br)cn2)c1 nan
16018254 30982 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 4 1.1 CNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
CHEMBL1398599 30982 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 4 1.1 CNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
16873489 31113 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 8 2.5 O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1cccc(-c2ccc3nncn3n2)c1 nan
CHEMBL1399932 31113 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 8 2.5 O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1cccc(-c2ccc3nncn3n2)c1 nan
20957244 31268 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 0 9 2.5 CCOc1ccc(N(C)C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1401299 31268 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 0 9 2.5 CCOc1ccc(N(C)C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
5053439 31283 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 6 1.2 COC(CNC(=O)c1ccc2nc3ccccc3c(=O)n2c1)OC nan
CHEMBL1401405 31283 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 6 1.2 COC(CNC(=O)c1ccc2nc3ccccc3c(=O)n2c1)OC nan
5734701 31480 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1 nan
CHEMBL1403145 31480 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1 nan
5302177 31566 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 0 5 2.0 O=c1nc2ccccn2c2ccc(S(=O)(=O)N3CCCCC3)cc12 nan
CHEMBL1404020 31566 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 0 5 2.0 O=c1nc2ccccn2c2ccc(S(=O)(=O)N3CCCCC3)cc12 nan
1504305 31769 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 5 0 7 1.7 Cc1cc(C)n(C(=O)CCCn2cc([N+](=O)[O-])cn2)n1 nan
CHEMBL1405977 31769 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 5 0 7 1.7 Cc1cc(C)n(C(=O)CCCn2cc([N+](=O)[O-])cn2)n1 nan
5221227 31999 None 12 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 10 -0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCN4CCOCC4)c3nc12 nan
CHEMBL1407863 31999 None 12 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 10 -0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCN4CCOCC4)c3nc12 nan
975666 32136 None 16 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 7 1.6 Cc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
CHEMBL1408899 32136 None 16 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 7 1.6 Cc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
3152548 32152 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1)c1ccco1 nan
CHEMBL1409014 32152 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1)c1ccco1 nan
3147984 32233 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 2.5 CCN(CC)C(=O)CSc1nnc2c3ccccc3n(C)c2n1 nan
CHEMBL1409671 32233 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 2.5 CCN(CC)C(=O)CSc1nnc2c3ccccc3n(C)c2n1 nan
2740105 32302 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 0 4 3.3 N#Cc1c(N2CCCC2)nsc1-c1ccccc1 nan
CHEMBL1410151 32302 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 0 4 3.3 N#Cc1c(N2CCCC2)nsc1-c1ccccc1 nan
2965406 32307 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 5 4.1 O=C(NCCCn1ccnc1)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1410223 32307 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 5 4.1 O=C(NCCCn1ccnc1)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
609181 32491 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 1 3 4.1 CC1(C(=O)Nc2nc3ccccc3s2)CC1(Br)Br nan
CHEMBL1411818 32491 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 1 3 4.1 CC1(C(=O)Nc2nc3ccccc3s2)CC1(Br)Br nan
2328662 32612 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 7 2.6 CCOC(=O)Cc1csc(-n2sc3ccccc3c2=O)n1 nan
CHEMBL1412731 32612 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 7 2.6 CCOC(=O)Cc1csc(-n2sc3ccccc3c2=O)n1 nan
716956 32853 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.5 COc1cc(-c2oc3ccc(C)cc3c(=O)c2O)cc(OC)c1OC nan
CHEMBL1414686 32853 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.5 COc1cc(-c2oc3ccc(C)cc3c(=O)c2O)cc(OC)c1OC nan
16019291 33196 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 4 5.2 Clc1cccc(CSc2ccc(-c3cccs3)nn2)c1 nan
CHEMBL1417757 33196 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 4 5.2 Clc1cccc(CSc2ccc(-c3cccs3)nn2)c1 nan
17581531 33218 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.5 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCCS3 nan
CHEMBL1417902 33218 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.5 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCCS3 nan
1505908 33419 None 7 Human Functional pPotency = 4.7 4.7 -21 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 1.5 Cc1c(F)cccc1NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C nan
CHEMBL1419634 33419 None 7 Human Functional pPotency = 4.7 4.7 -21 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 1.5 Cc1c(F)cccc1NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C nan
2138543 33706 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
CHEMBL1422079 33706 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
3937026 34270 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.5 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCC1 nan
CHEMBL1426645 34270 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.5 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCC1 nan
5909825 34913 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 1 9 2.5 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
CHEMBL1432124 34913 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 1 9 2.5 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
16011119 35193 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.2 Cc1ccc(CNC(=O)C(C)n2nc(C)n3c(cc4sccc43)c2=O)cc1 nan
CHEMBL1435058 35193 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.2 Cc1ccc(CNC(=O)C(C)n2nc(C)n3c(cc4sccc43)c2=O)cc1 nan
16018536 35319 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 5 5.2 O=C(NCc1cccs1)c1ccc2c(c1)sc1nc(-c3ccccc3)cn12 nan
CHEMBL1436706 35319 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 5 5.2 O=C(NCc1cccs1)c1ccc2c(c1)sc1nc(-c3ccccc3)cn12 nan
16011654 35325 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1ccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)cc1 nan
CHEMBL1436776 35325 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1ccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)cc1 nan
790330 35550 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2nc(C)cc(S)c2c1 nan
CHEMBL1439016 35550 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2nc(C)cc(S)c2c1 nan
22333977 35571 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)c(OC)c1 nan
CHEMBL1439223 35571 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)c(OC)c1 nan
974773 35736 None 5 Human Functional pPotency = 4.7 4.7 -19 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 1 2 2 2.9 O=C(O)c1ccc2cccc(Cl)c2c1O nan
CHEMBL1440675 35736 None 5 Human Functional pPotency = 4.7 4.7 -19 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 1 2 2 2.9 O=C(O)c1ccc2cccc(Cl)c2c1O nan
1048151 36234 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 3.8 COc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
CHEMBL1445229 36234 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 3.8 COc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
16407102 36240 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 8 1 9 2.8 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCN4CCOCC4)cc3c3ccnc2c31 nan
CHEMBL1445287 36240 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 8 1 9 2.8 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCN4CCOCC4)cc3c3ccnc2c31 nan
3244615 36649 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 8 1.2 O=C(Cn1cnc2sc3c(c2c1=O)CCCC3)NCCC(=O)N1CCC2(CC1)OCCO2 nan
CHEMBL1448799 36649 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 8 1.2 O=C(Cn1cnc2sc3c(c2c1=O)CCCC3)NCCC(=O)N1CCC2(CC1)OCCO2 nan
5333438 36750 None 5 Human Functional pPotency = 4.7 4.7 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 3 5 0.9 O=C(O)/C=C\C(=O)Nc1cc(O)ccc1[N+](=O)[O-] nan
CHEMBL1449557 36750 None 5 Human Functional pPotency = 4.7 4.7 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 3 5 0.9 O=C(O)/C=C\C(=O)Nc1cc(O)ccc1[N+](=O)[O-] nan
946874 37166 None 14 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 8 2.2 COC(=O)CSc1nc2ccccc2nc1SCC(=O)OC nan
CHEMBL1452913 37166 None 14 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 8 2.2 COC(=O)CSc1nc2ccccc2nc1SCC(=O)OC nan
15990397 37232 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 7 2.2 COc1cc(NC(=O)c2nc3ccccc3n(C)c2=O)cc(OC)c1OC nan
CHEMBL1453389 37232 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 7 2.2 COc1cc(NC(=O)c2nc3ccccc3n(C)c2=O)cc(OC)c1OC nan
2072948 37377 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 4 3.4 Brc1ccc2ncnc(NCc3cccnc3)c2c1 nan
CHEMBL1454562 37377 None 13 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 4 3.4 Brc1ccc2ncnc(NCc3cccnc3)c2c1 nan
20957239 37725 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 5 1 8 2.5 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1F nan
CHEMBL1457707 37725 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 5 1 8 2.5 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1F nan
8031083 37921 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 7 2.1 CCOC(=O)CCc1c(C)c2ccc3c(c2oc1=O)CN(CCCO)CO3 nan
CHEMBL1459326 37921 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 7 2.1 CCOC(=O)CCc1c(C)c2ccc3c(c2oc1=O)CN(CCCO)CO3 nan
1947745 38335 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
1947746 38335 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
CHEMBL1462881 38335 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
3593326 38357 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 8 1.1 CCOC(=O)C1=NN(c2ccc([N+](=O)[O-])cc2)CC1C(=O)OC nan
CHEMBL1463045 38357 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 8 1.1 CCOC(=O)C1=NN(c2ccc([N+](=O)[O-])cc2)CC1C(=O)OC nan
3889908 38441 None 11 Human Functional pPotency = 4.7 4.7 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
663903 38441 None 11 Human Functional pPotency = 4.7 4.7 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
CHEMBL1463781 38441 None 11 Human Functional pPotency = 4.7 4.7 1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
4834173 38663 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 6 2.7 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cccc(C#N)c2)c1 nan
CHEMBL1465419 38663 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 6 2.7 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cccc(C#N)c2)c1 nan
2124679 38753 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.7 O=C(COc1ncnc2ccc(Br)cc12)NCc1ccco1 nan
CHEMBL1466120 38753 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.7 O=C(COc1ncnc2ccc(Br)cc12)NCc1ccco1 nan
5840379 38889 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 4 1 9 0.8 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CC(C)OC(C)C3)nc12 nan
CHEMBL1467214 38889 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 4 1 9 0.8 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CC(C)OC(C)C3)nc12 nan
2824481 39041 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 5 3.9 N#Cc1c(N2CCSCC2)nsc1-c1ccccc1Cl nan
CHEMBL1468502 39041 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 5 3.9 N#Cc1c(N2CCSCC2)nsc1-c1ccccc1Cl nan
5911323 39165 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.0 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(C)cc2)cc1 nan
CHEMBL1469507 39165 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.0 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(C)cc2)cc1 nan
3186594 39346 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1471097 39346 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
5302637 39555 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 4 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2)cc1 nan
CHEMBL1473111 39555 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 4 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2)cc1 nan
16009440 39620 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 7 4.0 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1C nan
CHEMBL1474025 39620 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 7 4.0 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1C nan
16018838 39623 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 0 5 4.9 Clc1cccc(CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1474070 39623 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 0 5 4.9 Clc1cccc(CSc2nncn3c2cc2sccc23)c1 nan
16033266 39746 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.3 Cc1c(C(=O)NC(C)c2ccccc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1475712 39746 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.3 Cc1c(C(=O)NC(C)c2ccccc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
16030277 39750 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1 nan
CHEMBL1475778 39750 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1 nan
16018142 39773 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 6 1 2 4.0 Cn1cc(CCCC(=O)NCc2ccc(F)cc2)c2ccccc21 nan
CHEMBL1476187 39773 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 6 1 2 4.0 Cn1cc(CCCC(=O)NCc2ccc(F)cc2)c2ccccc21 nan
16018630 39781 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 4.0 O=C(CSc1nncn2c1cc1occc12)Nc1ccc(F)c(Cl)c1 nan
CHEMBL1476304 39781 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 4.0 O=C(CSc1nncn2c1cc1occc12)Nc1ccc(F)c(Cl)c1 nan
16018040 39795 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 6 3.1 COc1ccc(OC)c(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1476501 39795 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 6 3.1 COc1ccc(OC)c(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
135407487 39809 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(CNC(=O)CSc2nc3[nH]nc(C)c3c(=N)n2-c2ccccc2Cl)cc1 nan
CHEMBL1476621 39809 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(CNC(=O)CSc2nc3[nH]nc(C)c3c(=N)n2-c2ccccc2Cl)cc1 nan
676907 39908 None 34 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 205 1 1 3 2.8 COc1ccc2c(C)cc(S)nc2c1 nan
CHEMBL1477596 39908 None 34 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 205 1 1 3 2.8 COc1ccc2c(C)cc(S)nc2c1 nan
16018964 40146 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.2 CCC(C)NC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1479750 40146 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.2 CCC(C)NC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16018270 40642 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 5 5.5 CC(=O)Nc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
CHEMBL1484019 40642 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 5 5.5 CC(=O)Nc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
4613858 41038 None 16 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 1 2 7 0.9 COC(=O)c1sc2[nH]c(=S)n(N)c(=O)c2c1C nan
CHEMBL1487438 41038 None 16 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 1 2 7 0.9 COC(=O)c1sc2[nH]c(=S)n(N)c(=O)c2c1C nan
1173795 41187 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 1.9 CCCn1c(SCC(=O)Nc2ccc(NC(=O)CC)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1488482 41187 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 1.9 CCCn1c(SCC(=O)Nc2ccc(NC(=O)CC)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
3152454 41219 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 3 8 0.4 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1CCCO nan
CHEMBL1488709 41219 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 3 8 0.4 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1CCCO nan
1294912 41659 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 2 8 3.8 COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
CHEMBL1491898 41659 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 2 8 3.8 COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
3944710 41666 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 8 2.1 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cc(O)nc2ccccc12 nan
CHEMBL1491951 41666 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 8 2.1 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cc(O)nc2ccccc12 nan
2958357 41992 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 6 2.9 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCC3 nan
CHEMBL1494894 41992 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 6 2.9 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCC3 nan
3601528 42026 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 2 7 5.3 COc1ccc(C(=O)Nc2nc3n(n2)C(c2ccc(Cl)cc2)C=C(c2ccccc2)N3)cc1OC nan
CHEMBL1495241 42026 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 2 7 5.3 COc1ccc(C(=O)Nc2nc3n(n2)C(c2ccc(Cl)cc2)C=C(c2ccccc2)N3)cc1OC nan
3120647 42033 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 3 1 4 6.9 O=C(Nc1ccc2oc(-c3cc(Br)ccc3Cl)nc2c1)c1cc2ccccc2o1 nan
CHEMBL1495306 42033 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 3 1 4 6.9 O=C(Nc1ccc2oc(-c3cc(Br)ccc3Cl)nc2c1)c1cc2ccccc2o1 nan
3296097 42130 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 5 1 9 4.1 CCc1ccc(-n2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3nncc-3c2O)cc1 nan
CHEMBL1496299 42130 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 5 1 9 4.1 CCc1ccc(-n2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3nncc-3c2O)cc1 nan
2175955 42616 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3cccnc3)cc2)c1C nan
CHEMBL1500554 42616 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3cccnc3)cc2)c1C nan
2868511 42644 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 4 3.5 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(C)cc2)cc1 nan
CHEMBL1500746 42644 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 4 3.5 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(C)cc2)cc1 nan
3146565 42879 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 4.0 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1502935 42879 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 4.0 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
2998667 43051 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 9 -1.9 CC(=O)OCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1504458 43051 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 9 -1.9 CC(=O)OCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
2497236 43249 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 6 4.6 CCOc1ccc(-c2nc(-c3cccs3)c(CC(=O)O)s2)cc1OC nan
CHEMBL1506154 43249 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 6 4.6 CCOc1ccc(-c2nc(-c3cccs3)c(CC(=O)O)s2)cc1OC nan
1442564 43656 None 2 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 3.5 COC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
CHEMBL1509687 43656 None 2 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 3.5 COC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
6305743 43667 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 7 1 5 3.2 COCCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1509795 43667 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 7 1 5 3.2 COCCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
15988981 43950 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 8 2 7 4.1 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(=O)NCc3ccccc3Cl)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1512541 43950 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 8 2 7 4.1 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(=O)NCc3ccccc3Cl)c(=O)c3sccc32)c(C)c1 nan
1116224 44068 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.1 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(C(F)(F)F)c2)n(C)c1=O nan
CHEMBL1514415 44068 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.1 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(C(F)(F)F)c2)n(C)c1=O nan
16018038 44142 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 5 3.8 CSc1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
CHEMBL1515402 44142 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 5 3.8 CSc1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
16016056 44172 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 7 5.0 COc1ccccc1-c1noc(-c2ccc(NCCc3ccccc3)c([N+](=O)[O-])c2)n1 nan
CHEMBL1515947 44172 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 7 5.0 COc1ccccc1-c1noc(-c2ccc(NCCc3ccccc3)c([N+](=O)[O-])c2)n1 nan
5069160 44246 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
CHEMBL1516839 44246 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
5389765 44460 None 6 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 8 1 6 3.1 COCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
CHEMBL1518887 44460 None 6 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 8 1 6 3.1 COCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
1238913 44604 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 0 9 -1.1 Cn1c(=O)c2c(nc(SCC(=O)N3CCOCC3)n2C)n(C)c1=O nan
CHEMBL1520162 44604 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 0 9 -1.1 Cn1c(=O)c2c(nc(SCC(=O)N3CCOCC3)n2C)n(C)c1=O nan
2165182 44729 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 5 2.9 Cc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)o1 nan
CHEMBL1521212 44729 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 5 2.9 Cc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)o1 nan
3111808 44781 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1 nan
CHEMBL1521616 44781 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1 nan
20957509 44903 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1522776 44903 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
4126696 44918 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 5 5.9 COc1ccc(-n2cc(-c3ccccc3)nc2SCC(=O)Nc2ccccc2)cc1Cl nan
CHEMBL1522905 44918 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 5 5.9 COc1ccc(-n2cc(-c3ccccc3)nc2SCC(=O)Nc2ccccc2)cc1Cl nan
2561590 45277 None 3 Human Functional pPotency = 4.7 4.7 -3 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 0 8 4.1 Cc1cc(C(=O)CSc2nc3ccccc3c(=O)n2C)c(C)n1Cc1ccc2c(c1)OCO2 nan
CHEMBL1526230 45277 None 3 Human Functional pPotency = 4.7 4.7 -3 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 0 8 4.1 Cc1cc(C(=O)CSc2nc3ccccc3c(=O)n2C)c(C)n1Cc1ccc2c(c1)OCO2 nan
15991183 45428 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 1 4 6.8 O=C(Nc1cccc(-c2nc3ccccc3o2)c1)c1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1527553 45428 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 1 4 6.8 O=C(Nc1cccc(-c2nc3ccccc3o2)c1)c1ccc(-c2ccc(Br)cc2)o1 nan
16014288 45780 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 2 8 3.8 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3nc(SC(C)C)ncc3Cl)cc2)n1 nan
CHEMBL1530646 45780 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 2 8 3.8 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3nc(SC(C)C)ncc3Cl)cc2)n1 nan
6078364 45789 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)cc1 nan
CHEMBL1530717 45789 None 1 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)cc1 nan
950608 46175 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 1.5 N#C/C(=C\c1c(N2CCCCCC2)nc2ccccn2c1=O)C(N)=O nan
CHEMBL1534139 46175 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 1.5 N#C/C(=C\c1c(N2CCCCCC2)nc2ccccn2c1=O)C(N)=O nan
5310696 46189 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 10 1 6 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OCC(C)C)cc2C)C1c1cccnc1 nan
CHEMBL1534309 46189 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 10 1 6 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OCC(C)C)cc2C)C1c1cccnc1 nan
1856407 46425 None 14 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 1.1 CCOC(=O)N1CCN(c2nc3c(C)cccn3c(=O)c2C=O)CC1 nan
CHEMBL1536792 46425 None 14 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 1.1 CCOC(=O)N1CCN(c2nc3c(C)cccn3c(=O)c2C=O)CC1 nan
1442728 46480 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 4 4.3 CC(C)c1nc(SCC(=O)NC2CCCCC2)c2ccccc2n1 nan
CHEMBL1537182 46480 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 4 4.3 CC(C)c1nc(SCC(=O)NC2CCCCC2)c2ccccc2n1 nan
6165328 46725 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 6 4.3 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Cl)cc2)cc1 nan
CHEMBL1539268 46725 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 6 4.3 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Cl)cc2)cc1 nan
2944889 46921 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 10 1 7 5.1 CCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccco2)cc1OCC nan
CHEMBL1540923 46921 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 10 1 7 5.1 CCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccco2)cc1OCC nan
1867273 47399 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
CHEMBL1544770 47399 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
3600899 47430 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 9 4.3 O=c1cc(CSc2nc3nncc-3c(O)n2-c2ccc(Br)cc2)nc2ccc(Br)cn12 nan
CHEMBL1545051 47430 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 9 4.3 O=c1cc(CSc2nc3nncc-3c(O)n2-c2ccc(Br)cc2)nc2ccc(Br)cn12 nan
135514845 47629 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 8 2.7 CN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
CHEMBL1546713 47629 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 8 2.7 CN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
1442627 47836 None 3 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 2 6 3.1 CCCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
CHEMBL1548632 47836 None 3 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 2 6 3.1 CCCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
16016034 48216 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 1 7 4.1 COc1ccccc1-c1noc(-c2ccc(NC(C)C)c([N+](=O)[O-])c2)n1 nan
CHEMBL1552261 48216 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 1 7 4.1 COc1ccccc1-c1noc(-c2ccc(NC(C)C)c([N+](=O)[O-])c2)n1 nan
16017890 48233 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 1.5 COCCCNC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
CHEMBL1552564 48233 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 1.5 COCCCNC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
16023050 48234 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 3.1 CCNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)C1 nan
CHEMBL1552569 48234 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 3.1 CCNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)C1 nan
3260331 48291 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 3 4.6 O=C(Cn1cc(C(=O)C2CC2)c2ccccc21)Nc1ccc(Br)cc1 nan
CHEMBL1553312 48291 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 3 4.6 O=C(Cn1cc(C(=O)C2CC2)c2ccccc21)Nc1ccc(Br)cc1 nan
16030436 48366 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 2.9 CC(C)C(=O)Nc1ccccc1OCc1cc(=O)n2ccccc2n1 nan
CHEMBL1554451 48366 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 2.9 CC(C)C(=O)Nc1ccccc1OCc1cc(=O)n2ccccc2n1 nan
16016784 48424 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 5.4 CCOC(=O)C1CCCN(C(=O)c2[nH]c3ccccc3c2Sc2ccc(Cl)cc2)C1 nan
CHEMBL1555295 48424 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 5.4 CCOC(=O)C1CCCN(C(=O)c2[nH]c3ccccc3c2Sc2ccc(Cl)cc2)C1 nan
16196698 48447 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 7 1.9 Cc1cc2nnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)n2c2ccccc12 nan
CHEMBL1555603 48447 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 7 1.9 Cc1cc2nnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)n2c2ccccc12 nan
2869543 48616 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 3.9 CCOC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
CHEMBL1557161 48616 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 3.9 CCOC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
1272771 48656 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 6 5.4 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)cc4C)sc3n2)cc1OC nan
CHEMBL1557478 48656 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 6 5.4 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)cc4C)sc3n2)cc1OC nan
3239737 48793 None 0 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 7 1.4 Cc1nn(C(C)C(=O)NCC2CCCO2)c(=O)c2cc3occc3n12 nan
CHEMBL1558668 48793 None 0 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 7 1.4 Cc1nn(C(C)C(=O)NCC2CCCO2)c(=O)c2cc3occc3n12 nan
1503106 48984 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 5 3.1 Cc1cc(CNC(=O)COc2ccc([N+](=O)[O-])cc2)c2ccccc2n1 nan
CHEMBL1560348 48984 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 5 3.1 Cc1cc(CNC(=O)COc2ccc([N+](=O)[O-])cc2)c2ccccc2n1 nan
2456723 49269 None 3 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 2 8 3.7 CCOC(=O)c1cc(-c2ccccc2)sc1NC(=O)COC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 nan
CHEMBL1562996 49269 None 3 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 2 8 3.7 CCOC(=O)c1cc(-c2ccccc2)sc1NC(=O)COC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 nan
3221518 49378 None 3 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 8 1 5 3.8 CCCNC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1563919 49378 None 3 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 8 1 5 3.8 CCCNC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
2952819 49443 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.3 O=C(Cn1nc(-c2cccc([N+](=O)[O-])c2)c2ccccc2c1=O)NCC1CCCO1 nan
CHEMBL1564585 49443 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.3 O=C(Cn1nc(-c2cccc([N+](=O)[O-])c2)c2ccccc2c1=O)NCC1CCCO1 nan
2869470 49640 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 0 5 3.6 Cc1nnc(Oc2ccc([N+](=O)[O-])cc2)c2ccccc12 nan
CHEMBL1566109 49640 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 0 5 3.6 Cc1nnc(Oc2ccc([N+](=O)[O-])cc2)c2ccccc12 nan
16008434 49730 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 5 4.7 O=C(c1ccc(Cl)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCCO3 nan
CHEMBL1566810 49730 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 5 4.7 O=C(c1ccc(Cl)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCCO3 nan
1017457 49838 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 11 0.2 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC3CCCCC3)n2C)n(C)c1=O nan
CHEMBL1567667 49838 None 11 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 11 0.2 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC3CCCCC3)n2C)n(C)c1=O nan
2912191 49928 None 12 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 4.4 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)cc2)o1 nan
CHEMBL1568384 49928 None 12 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 4.4 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)cc2)o1 nan
665555 50225 None 5 Human Functional pPotency = 4.7 4.7 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 5 4.9 Cc1nc(SCC(=O)Nc2ccc(C)c(F)c2)c2oc3ccccc3c2n1 nan
CHEMBL1570874 50225 None 5 Human Functional pPotency = 4.7 4.7 -1 3
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 5 4.9 Cc1nc(SCC(=O)Nc2ccc(C)c(F)c2)c2oc3ccccc3c2n1 nan
4333346 50424 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 4 4.3 COc1ccc(CCNC(=O)CSc2ccc3ccccc3c2)cc1OC nan
CHEMBL1572841 50424 None 2 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 4 4.3 COc1ccc(CCNC(=O)CSc2ccc3ccccc3c2)cc1OC nan
20957497 50631 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 10 2 7 2.1 Cc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1574892 50631 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 10 2 7 2.1 Cc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
1938572 50847 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 6 3.6 O=C(COc1ccccc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
CHEMBL1576963 50847 None 6 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 6 3.6 O=C(COc1ccccc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
1632391 51001 None 12 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 3 4 2.0 O=C(O)CCC(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
CHEMBL1578274 51001 None 12 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 3 4 2.0 O=C(O)CCC(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
3504887 51053 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 7 1.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC1 nan
CHEMBL1578618 51053 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 7 1.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC1 nan
20903631 51059 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 0 9 1.2 COc1cccc(N2CCN(c3ccc4nnc(CCC(=O)N5CCN(C)CC5)n4n3)CC2)c1 nan
CHEMBL1578662 51059 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 0 9 1.2 COc1cccc(N2CCN(c3ccc4nnc(CCC(=O)N5CCN(C)CC5)n4n3)CC2)c1 nan
16475 51702 None 31 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 4 4 1.9 Nc1ccc(-c2ccc(N)c(C(=O)O)c2)cc1C(=O)O nan
CHEMBL1584156 51702 None 31 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 4 4 1.9 Nc1ccc(-c2ccc(N)c(C(=O)O)c2)cc1C(=O)O nan
1997175 51749 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 0 7 0.9 CN1CCN(c2nc3ccccn3c(=O)c2C=C(C#N)C#N)CC1 nan
CHEMBL1584587 51749 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 0 7 0.9 CN1CCN(c2nc3ccccn3c(=O)c2C=C(C#N)C#N)CC1 nan
20881207 51993 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 10 1 8 2.5 CC(C)OCCCn1c(=O)c2ccccc2n2c(CCC(=O)NCc3ccccn3)nnc12 nan
CHEMBL1586569 51993 None 7 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 10 1 8 2.5 CC(C)OCCCn1c(=O)c2ccccc2n2c(CCC(=O)NCc3ccccn3)nnc12 nan
3186634 51994 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 0 9 -1.2 CN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
CHEMBL1586576 51994 None 3 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 0 9 -1.2 CN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
658021 52269 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 0 5 3.0 CSC1=NP(=S)(SC)N(C)c2nc3n(c21)CCC3 nan
CHEMBL1588879 52269 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 0 5 3.0 CSC1=NP(=S)(SC)N(C)c2nc3n(c21)CCC3 nan
7190667 52379 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1cccc(F)c1 nan
CHEMBL1589799 52379 None 9 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1cccc(F)c1 nan
16030609 52422 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 0 5 5.7 CCN(C(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1)c1cccc(C)c1 nan
CHEMBL1590288 52422 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 0 5 5.7 CCN(C(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1)c1cccc(C)c1 nan
6221827 52452 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.0 COc1ccc(CNC(=O)Cc2c(C)c3c(O)cc(C)cc3oc2=O)cc1 nan
CHEMBL1590750 52452 None 10 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.0 COc1ccc(CNC(=O)Cc2c(C)c3c(O)cc(C)cc3oc2=O)cc1 nan
16030275 52534 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 0 4 4.9 CCCCN(C)C(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
CHEMBL1591718 52534 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 0 4 4.9 CCCCN(C)C(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
16031876 52586 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 5 5.0 CCC1CCCCN1Cc1cn2c(-c3ccc(Br)cc3)nnc2s1 nan
CHEMBL1592401 52586 None 8 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 5 5.0 CCC1CCCCN1Cc1cn2c(-c3ccc(Br)cc3)nnc2s1 nan
5768121 52798 None 7 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 6 4.6 Cc1cc(OCC(C)C)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
CHEMBL1594882 52798 None 7 Human Functional pPotency = 4.7 4.7 -1 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 6 4.6 Cc1cc(OCC(C)C)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
4968658 52908 None 3 Human Functional pPotency = 4.7 4.7 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3ccc(Cl)cc3)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1595841 52908 None 3 Human Functional pPotency = 4.7 4.7 -5 2
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3ccc(Cl)cc3)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
4875333 53533 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 4 3.5 CCn1c2ccccc2c2nc3cc(C(=O)O)ccc3nc21 nan
CHEMBL1601617 53533 None 4 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 4 3.5 CCn1c2ccccc2c2nc3cc(C(=O)O)ccc3nc21 nan
15988911 53850 None 5 Human Functional pPotency = 4.7 4.7 - 1
PUBCHEM_BIOASSAY: qHTS Ass