Ligand source activities (1 row/activity)
| Ligands | Receptor | Assay information | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name |
GPCRdb ID | #Vendors | Reference ligand |
Fold selectivity (Potency) |
# tested GPCRs (Potency) |
Species | p-value (-log) |
Type | Activity Relation |
Activity Value |
Assay Type | Assay Description | Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI |
| 1499 | 2060 | 43 | None | -63 | 36 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 3779 | 2060 | 43 | None | -63 | 36 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 536 | 2060 | 43 | None | -63 | 36 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| CHEMBL434 | 2060 | 43 | None | -63 | 36 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| DB01064 | 2060 | 43 | None | -63 | 36 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 1499 | 2060 | 43 | None | -63 | 36 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 3779 | 2060 | 43 | None | -63 | 36 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 536 | 2060 | 43 | None | -63 | 36 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| CHEMBL434 | 2060 | 43 | None | -63 | 36 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| DB01064 | 2060 | 43 | None | -63 | 36 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 1183 | 3908 | 0 | None | -1 | 3 | Human | 3.1 | pEC50 | = | 3.1 | Functional | Guide to Pharmacology | 152 | 2 | 1 | 3 | 1.2 | COc1cc(C=O)ccc1O | 34307435 | ||
| 6412 | 3908 | 0 | None | -1 | 3 | Human | 3.1 | pEC50 | = | 3.1 | Functional | Guide to Pharmacology | 152 | 2 | 1 | 3 | 1.2 | COc1cc(C=O)ccc1O | 34307435 | ||
| CHEMBL13883 | 3908 | 0 | None | -1 | 3 | Human | 3.1 | pEC50 | = | 3.1 | Functional | Guide to Pharmacology | 152 | 2 | 1 | 3 | 1.2 | COc1cc(C=O)ccc1O | 34307435 | ||
| 12497 | 1542 | 97 | None | -13 | 2 | Human | 3.4 | pEC50 | = | 3.4 | Functional | Guide to Pharmacology | 290 | 1 | 5 | 6 | 1.5 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O | 21272567 | ||
| 72276 | 1542 | 97 | None | -13 | 2 | Human | 3.4 | pEC50 | = | 3.4 | Functional | Guide to Pharmacology | 290 | 1 | 5 | 6 | 1.5 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O | 21272567 | ||
| CHEMBL583912 | 1542 | 97 | None | -13 | 2 | Human | 3.4 | pEC50 | = | 3.4 | Functional | Guide to Pharmacology | 290 | 1 | 5 | 6 | 1.5 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O | 21272567 | ||
| DB12039 | 1542 | 97 | None | -13 | 2 | Human | 3.4 | pEC50 | = | 3.4 | Functional | Guide to Pharmacology | 290 | 1 | 5 | 6 | 1.5 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O | 21272567 | ||
| 12461 | 1544 | 76 | None | - | 1 | Human | 3.4 | pEC50 | = | 3.4 | Functional | Guide to Pharmacology | 306 | 1 | 6 | 7 | 1.3 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O | 21272567 | ||
| 72277 | 1544 | 76 | None | - | 1 | Human | 3.4 | pEC50 | = | 3.4 | Functional | Guide to Pharmacology | 306 | 1 | 6 | 7 | 1.3 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O | 21272567 | ||
| CHEMBL47386 | 1544 | 76 | None | - | 1 | Human | 3.4 | pEC50 | = | 3.4 | Functional | Guide to Pharmacology | 306 | 1 | 6 | 7 | 1.3 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O | 21272567 | ||
| DB03823 | 1544 | 76 | None | - | 1 | Human | 3.4 | pEC50 | = | 3.4 | Functional | Guide to Pharmacology | 306 | 1 | 6 | 7 | 1.3 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O | 21272567 | ||
| 12441 | 3091 | 0 | None | -1 | 2 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 242 | 1 | 2 | 3 | 2.8 | C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O | 21942422 | ||
| 382975 | 3091 | 0 | None | -1 | 2 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 242 | 1 | 2 | 3 | 2.8 | C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O | 21942422 | ||
| CHEMBL1957037 | 3091 | 0 | None | -1 | 2 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 242 | 1 | 2 | 3 | 2.8 | C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O | 21942422 | ||
| 2826 | 1754 | 130 | None | -48 | 7 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 270 | 1 | 3 | 5 | 2.6 | Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O | 21942422 | ||
| 5280961 | 1754 | 130 | None | -48 | 7 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 270 | 1 | 3 | 5 | 2.6 | Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O | 21942422 | ||
| CHEMBL44 | 1754 | 130 | None | -48 | 7 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 270 | 1 | 3 | 5 | 2.6 | Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O | 21942422 | ||
| DB01645 | 1754 | 130 | None | -48 | 7 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 270 | 1 | 3 | 5 | 2.6 | Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O | 21942422 | ||
| 12440 | 1299 | 0 | None | -4 | 2 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | C1=CC=C(C(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O | 24117141 | ||
| 5281610 | 1299 | 0 | None | -4 | 2 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | C1=CC=C(C(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O | 24117141 | ||
| CHEMBL503168 | 1299 | 0 | None | -4 | 2 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | C1=CC=C(C(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O | 24117141 | ||
| 4285 | 3061 | 117 | None | -2 | 3 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 274 | 4 | 4 | 5 | 2.3 | Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O | 24117141 | ||
| 4788 | 3061 | 117 | None | -2 | 3 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 274 | 4 | 4 | 5 | 2.3 | Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O | 24117141 | ||
| CHEMBL45068 | 3061 | 117 | None | -2 | 3 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 274 | 4 | 4 | 5 | 2.3 | Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O | 24117141 | ||
| DB07810 | 3061 | 117 | None | -2 | 3 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 274 | 4 | 4 | 5 | 2.3 | Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O | 24117141 | ||
| 12463 | 3507 | 0 | None | - | 1 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O | 24117141 | ||
| 5281697 | 3507 | 0 | None | - | 1 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O | 24117141 | ||
| CHEMBL55415 | 3507 | 0 | None | - | 1 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O | 24117141 | ||
| 10298 | 2696 | 0 | None | - | 1 | Human | 4.5 | pEC50 | = | 4.5 | Functional | Guide to Pharmacology | 272 | 1 | 3 | 5 | 2.5 | Oc1ccc(cc1)C1CC(=O)c2c(O1)cc(cc2O)O | 24117141 | ||
| 932 | 2696 | 0 | None | - | 1 | Human | 4.5 | pEC50 | = | 4.5 | Functional | Guide to Pharmacology | 272 | 1 | 3 | 5 | 2.5 | Oc1ccc(cc1)C1CC(=O)c2c(O1)cc(cc2O)O | 24117141 | ||
| CHEMBL32571 | 2696 | 0 | None | - | 1 | Human | 4.5 | pEC50 | = | 4.5 | Functional | Guide to Pharmacology | 272 | 1 | 3 | 5 | 2.5 | Oc1ccc(cc1)C1CC(=O)c2c(O1)cc(cc2O)O | 24117141 | ||
| 107905 | 1543 | 79 | None | - | 1 | Human | 4.7 | pEC50 | = | 4.7 | Functional | Guide to Pharmacology | 442 | 3 | 7 | 10 | 2.5 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O | 25273142 | ||
| 12462 | 1543 | 79 | None | - | 1 | Human | 4.7 | pEC50 | = | 4.7 | Functional | Guide to Pharmacology | 442 | 3 | 7 | 10 | 2.5 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O | 25273142 | ||
| CHEMBL36327 | 1543 | 79 | None | - | 1 | Human | 4.7 | pEC50 | = | 4.7 | Functional | Guide to Pharmacology | 442 | 3 | 7 | 10 | 2.5 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O | 25273142 | ||
| 5215 | 2354 | 128 | None | -1 | 4 | Human | 5.1 | pEC50 | = | 5.1 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | Oc1cc(O)c2c(c1)oc(cc2=O)c1ccc(c(c1)O)O | 24117141 | ||
| 5280445 | 2354 | 128 | None | -1 | 4 | Human | 5.1 | pEC50 | = | 5.1 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | Oc1cc(O)c2c(c1)oc(cc2=O)c1ccc(c(c1)O)O | 24117141 | ||
| CHEMBL151 | 2354 | 128 | None | -1 | 4 | Human | 5.1 | pEC50 | = | 5.1 | Functional | Guide to Pharmacology | 286 | 1 | 4 | 6 | 2.3 | Oc1cc(O)c2c(c1)oc(cc2=O)c1ccc(c(c1)O)O | 24117141 | ||
| 12464 | 3738 | 0 | None | - | 1 | Human | 5.6 | pEC50 | = | 5.6 | Functional | Guide to Pharmacology | 564 | 2 | 9 | 12 | 2.2 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC4=C(C(=C(C=C4[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)O)O)O)C(=O)C(=C3)O)O | 25273142 | ||
| 135403798 | 3738 | 0 | None | - | 1 | Human | 5.6 | pEC50 | = | 5.6 | Functional | Guide to Pharmacology | 564 | 2 | 9 | 12 | 2.2 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC4=C(C(=C(C=C4[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)O)O)O)C(=O)C(=C3)O)O | 25273142 | ||
| 12465 | 3739 | 0 | None | - | 1 | Human | 6.2 | pEC50 | = | 6.2 | Functional | Guide to Pharmacology | 716 | 4 | 11 | 16 | 3.2 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C4=C3C=C(C=C(C4=O)O)[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)O | 25273142 | ||
| 135458101 | 3739 | 0 | None | - | 1 | Human | 6.2 | pEC50 | = | 6.2 | Functional | Guide to Pharmacology | 716 | 4 | 11 | 16 | 3.2 | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C4=C3C=C(C=C(C4=O)O)[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)O | 25273142 | ||
| 12466 | 163 | 0 | None | - | 1 | Human | 4.7 | pIC50 | = | 4.7 | Functional | Guide to Pharmacology | 236 | 1 | 0 | 2 | 3.8 | CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3 | 24722342 | ||
| 689013 | 163 | 0 | None | - | 1 | Human | 4.7 | pIC50 | = | 4.7 | Functional | Guide to Pharmacology | 236 | 1 | 0 | 2 | 3.8 | CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3 | 24722342 | ||
| CHEMBL134291 | 163 | 0 | None | - | 1 | Human | 4.7 | pIC50 | = | 4.7 | Functional | Guide to Pharmacology | 236 | 1 | 0 | 2 | 3.8 | CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3 | 24722342 | ||
| Ligands | Receptor | Assay information | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name |
GPCRdb ID | #Vendors | Reference ligand |
Fold selectivity (Affinity) |
# tested GPCRs (Affinity) |
Species | p-value (-log) |
Type | Activity Relation |
Activity Value |
Assay Type | Assay Description | Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI |