Ligand source activities (1 row/activity)
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
AssayType |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
17725 | 22357 | 85 | None | - | 1 | Human | 4.0 | pEC50 | = | 4 | Functional | ChEMBL | 132 | 0 | 0 | 1 | 0.4 | CN(C)C(=S)N(C)C | nan | ||
CHEMBL12214 | 22357 | 85 | None | - | 1 | Human | 4.0 | pEC50 | = | 4 | Functional | ChEMBL | 132 | 0 | 0 | 1 | 0.4 | CN(C)C(=S)N(C)C | nan | ||
2723593 | 180026 | 52 | None | - | 1 | Human | 4.8 | pEC50 | = | 4.8 | Functional | ChEMBL | 118 | 0 | 2 | 2 | -0.6 | CC(=O)NC(N)=S | nan | ||
CHEMBL4524588 | 180026 | 52 | None | - | 1 | Human | 4.8 | pEC50 | = | 4.8 | Functional | ChEMBL | 118 | 0 | 2 | 2 | -0.6 | CC(=O)NC(N)=S | nan | ||
820777 | 143482 | 70 | None | - | 1 | Human | 4.8 | pEC50 | = | 4.8 | Functional | ChEMBL | 151 | 1 | 1 | 1 | 2.4 | CC(=S)Nc1ccccc1 | nan | ||
CHEMBL3740596 | 143482 | 70 | None | - | 1 | Human | 4.8 | pEC50 | = | 4.8 | Functional | ChEMBL | 151 | 1 | 1 | 1 | 2.4 | CC(=S)Nc1ccccc1 | nan | ||
12496 | 9875 | 99 | None | 2 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 152 | 1 | 2 | 1 | 1.3 | C1=CC=C(C=C1)NC(=S)N | nan | ||
676454 | 9875 | 99 | None | 2 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 152 | 1 | 2 | 1 | 1.3 | C1=CC=C(C=C1)NC(=S)N | nan | ||
CHEMBL263376 | 9875 | 99 | None | 2 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 152 | 1 | 2 | 1 | 1.3 | C1=CC=C(C=C1)NC(=S)N | nan | ||
DB03694 | 9875 | 99 | None | 2 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 152 | 1 | 2 | 1 | 1.3 | C1=CC=C(C=C1)NC(=S)N | nan | ||
2308 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | nan | ||
657298 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | nan | ||
6650 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | nan | ||
CHEMBL1518 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | nan | ||
DB00550 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | nan | ||
700999 | 105145 | 82 | None | - | 1 | Human | 5.6 | pEC50 | = | 5.6 | Functional | ChEMBL | 228 | 2 | 2 | 1 | 3.5 | S=C(Nc1ccccc1)Nc1ccccc1 | nan | ||
CHEMBL275260 | 105145 | 82 | None | - | 1 | Human | 5.6 | pEC50 | = | 5.6 | Functional | ChEMBL | 228 | 2 | 2 | 1 | 3.5 | S=C(Nc1ccccc1)Nc1ccccc1 | nan | ||
1499 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
3779 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
536 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
CHEMBL434 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
DB01064 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
697057 | 22049 | 110 | None | - | 1 | Human | 6.3 | pEC50 | = | 6.3 | Functional | ChEMBL | 204 | 1 | 2 | 2 | 2.1 | O=c1cc(-c2ccccc2)[nH]c(=S)[nH]1 | nan | ||
CHEMBL1212975 | 22049 | 110 | None | - | 1 | Human | 6.3 | pEC50 | = | 6.3 | Functional | ChEMBL | 204 | 1 | 2 | 2 | 2.1 | O=c1cc(-c2ccccc2)[nH]c(=S)[nH]1 | nan | ||
69794 | 180297 | 77 | None | - | 1 | Human | 4.3 | pEC50 | = | 4.3 | Functional | ChEMBL | 89 | 1 | 0 | 1 | 0.5 | CN(C)C=S | nan | ||
CHEMBL4530853 | 180297 | 77 | None | - | 1 | Human | 4.3 | pEC50 | = | 4.3 | Functional | ChEMBL | 89 | 1 | 0 | 1 | 0.5 | CN(C)C=S | nan | ||
2308 | 9962 | 106 | None | 34 | 2 | Human | 8.2 | pEC50 | = | 8.2 | Functional | Drug Central | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | None | ||
657298 | 9962 | 106 | None | 34 | 2 | Human | 8.2 | pEC50 | = | 8.2 | Functional | Drug Central | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | None | ||
6650 | 9962 | 106 | None | 34 | 2 | Human | 8.2 | pEC50 | = | 8.2 | Functional | Drug Central | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | None | ||
CHEMBL1518 | 9962 | 106 | None | 34 | 2 | Human | 8.2 | pEC50 | = | 8.2 | Functional | Drug Central | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | None | ||
DB00550 | 9962 | 106 | None | 34 | 2 | Human | 8.2 | pEC50 | = | 8.2 | Functional | Drug Central | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | None | ||
1499 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
3779 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
536 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
CHEMBL434 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
DB01064 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
1349907 | 9277 | 0 | None | - | 1 | Human | 4.0 | pEC50 | = | 4.0 | Functional | Guide to Pharmacology | 114 | 0 | 1 | 3 | 0.7 | Cn1ccnc1S | 23632915 | ||
1745 | 9277 | 0 | None | - | 1 | Human | 4.0 | pEC50 | = | 4.0 | Functional | Guide to Pharmacology | 114 | 0 | 1 | 3 | 0.7 | Cn1ccnc1S | 23632915 | ||
6649 | 9277 | 0 | None | - | 1 | Human | 4.0 | pEC50 | = | 4.0 | Functional | Guide to Pharmacology | 114 | 0 | 1 | 3 | 0.7 | Cn1ccnc1S | 23632915 | ||
CHEMBL1515 | 9277 | 0 | None | - | 1 | Human | 4.0 | pEC50 | = | 4.0 | Functional | Guide to Pharmacology | 114 | 0 | 1 | 3 | 0.7 | Cn1ccnc1S | 23632915 | ||
DB00763 | 9277 | 0 | None | - | 1 | Human | 4.0 | pEC50 | = | 4.0 | Functional | Guide to Pharmacology | 114 | 0 | 1 | 3 | 0.7 | Cn1ccnc1S | 23632915 | ||
12495 | 8615 | 0 | None | - | 1 | Human | 4.2 | pEC50 | = | 4.2 | Functional | Guide to Pharmacology | 129 | 1 | 1 | 2 | 0.4 | C=CC1CNC(=S)O1 | 20551074 | ||
3034683 | 8615 | 0 | None | - | 1 | Human | 4.2 | pEC50 | = | 4.2 | Functional | Guide to Pharmacology | 129 | 1 | 1 | 2 | 0.4 | C=CC1CNC(=S)O1 | 20551074 | ||
CHEMBL508652 | 8615 | 0 | None | - | 1 | Human | 4.2 | pEC50 | = | 4.2 | Functional | Guide to Pharmacology | 129 | 1 | 1 | 2 | 0.4 | C=CC1CNC(=S)O1 | 20551074 | ||
12496 | 9875 | 99 | None | 2 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 152 | 1 | 2 | 1 | 1.3 | C1=CC=C(C=C1)NC(=S)N | 15723792 | ||
676454 | 9875 | 99 | None | 2 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 152 | 1 | 2 | 1 | 1.3 | C1=CC=C(C=C1)NC(=S)N | 15723792 | ||
CHEMBL263376 | 9875 | 99 | None | 2 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 152 | 1 | 2 | 1 | 1.3 | C1=CC=C(C=C1)NC(=S)N | 15723792 | ||
DB03694 | 9875 | 99 | None | 2 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 152 | 1 | 2 | 1 | 1.3 | C1=CC=C(C=C1)NC(=S)N | 15723792 | ||
2308 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | 15723792 | ||
657298 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | 15723792 | ||
6650 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | 15723792 | ||
CHEMBL1518 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | 15723792 | ||
DB00550 | 9962 | 106 | None | 34 | 2 | Human | 5.7 | pEC50 | = | 5.7 | Functional | Guide to Pharmacology | 170 | 2 | 2 | 2 | 1.4 | CCCc1cc(=O)[nH]c(=S)[nH]1 | 15723792 | ||
2268 | 9944 | 0 | None | 1 | 2 | Human | 3.7 | pIC50 | = | 3.7 | Functional | Guide to Pharmacology | 285 | 7 | 1 | 3 | 2.2 | CCCN(S(=O)(=O)c1ccc(cc1)C(=O)O)CCC | 21629661 | ||
4357 | 9944 | 0 | None | 1 | 2 | Human | 3.7 | pIC50 | = | 3.7 | Functional | Guide to Pharmacology | 285 | 7 | 1 | 3 | 2.2 | CCCN(S(=O)(=O)c1ccc(cc1)C(=O)O)CCC | 21629661 | ||
4911 | 9944 | 0 | None | 1 | 2 | Human | 3.7 | pIC50 | = | 3.7 | Functional | Guide to Pharmacology | 285 | 7 | 1 | 3 | 2.2 | CCCN(S(=O)(=O)c1ccc(cc1)C(=O)O)CCC | 21629661 | ||
CHEMBL897 | 9944 | 0 | None | 1 | 2 | Human | 3.7 | pIC50 | = | 3.7 | Functional | Guide to Pharmacology | 285 | 7 | 1 | 3 | 2.2 | CCCN(S(=O)(=O)c1ccc(cc1)C(=O)O)CCC | 21629661 | ||
DB01032 | 9944 | 0 | None | 1 | 2 | Human | 3.7 | pIC50 | = | 3.7 | Functional | Guide to Pharmacology | 285 | 7 | 1 | 3 | 2.2 | CCCN(S(=O)(=O)c1ccc(cc1)C(=O)O)CCC | 21629661 |
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity |
Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
Assay Type |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |