Variation Browser

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Receptor Position GPCRdb Segment Variant Mutation type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
Receptor Position GPCRdb Segment Variant Mutation Type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
casr_human 25 N-term R => Ter stop gained 1.649e-05 2 121280 0 None None
casr_human 101 N-term C => Ter stop gained 8.237e-06 1 121410 0 None None
casr_human 159 N-term L => SerfsTer98 frameshift 8.282e-06 1 120746 0 None None
casr_human 389 N-term T => GlnfsTer21 frameshift 8.237e-06 1 121402 0 None None
casr_human 545 N-term D => SerfsTer92 frameshift 8.237e-06 1 121410 0 None None
casr_human 658 2.46x46 TM2 L => Ter stop gained 8.244e-06 1 121294 0 None None
casr_human 993 C-term T => ArgfsTer25 frameshift 8.242e-06 1 121328 0 None None
casr_human 11 N-term L => S missense 8.243e-06 1 121314 0 nan 0.402
casr_human 14 N-term T => A missense 1.648e-05 2 121326 0 nan 0.001
casr_human 16 N-term H => Y missense 8.242e-06 1 121328 0 1.0 0.001
casr_human 18 N-term S => F missense 1.648e-05 2 121334 0 nan 0.672
casr_human 25 N-term R => Q missense 1.649e-05 2 121280 0 0.11 0.983
casr_human 31 N-term D => E missense 8.251e-06 1 121200 0 0.06 0.972
casr_human 33 N-term I => S missense 3.301e-05 4 121190 0 0.02 0.217
casr_human 45 N-term A => G missense 8.267e-06 1 120968 0 0.17 0.228
casr_human 45 N-term A => E missense 8.267e-06 1 120968 0 0.51 0.041
casr_human 60 N-term C => Y missense 8.304e-06 1 120428 0 0.0 1.0
casr_human 69 N-term R => H missense 1.648e-05 2 121364 0 0.0 1.0
casr_human 74 N-term M => L missense 8.239e-06 1 121378 0 0.01 0.996
casr_human 78 N-term I => V missense 1.648e-05 2 121388 0 0.09 0.605
casr_human 89 N-term P => R missense 8.237e-06 1 121406 0 0.0 1.0
casr_human 90 N-term N => T missense 8.237e-06 1 121406 0 0.0 0.993 PTM (N-linked Glycosylation)
casr_human 92 N-term T => M missense 8.237e-06 1 121408 0 0.0 0.991
casr_human 103 N-term T => I missense 2.471e-05 3 121410 0 0.03 0.997
casr_human 122 N-term S => Y missense 8.238e-06 1 121388 0 0.05 0.995
casr_human 140 N-term A => V missense 8.244e-06 1 121304 0 0.09 0.99
casr_human 143 N-term G => R missense 8.247e-06 1 121258 0 0.0 1.0
casr_human 144 N-term A => T missense 8.247e-06 1 121256 0 0.56 0.993
casr_human 149 N-term V => I missense 8.257e-06 1 121112 0 0.48 0.004
casr_human 152 N-term A => V missense 1.653e-05 2 120994 0 0.14 0.644
casr_human 159 N-term L => V missense 8.283e-06 1 120736 0 0.53 0.487
casr_human 175 N-term S => R missense 8.251e-06 1 121196 0 0.0 1.0
casr_human 176 N-term N => K missense 1.65e-05 2 121210 0 0.02 0.99
casr_human 187 N-term I => T missense 8.245e-06 1 121282 0 0.0 0.932
casr_human 189 N-term N => S missense 8.244e-06 1 121300 0 1.0 0.057
casr_human 191 N-term E => G missense 8.244e-06 1 121302 0 0.3 0.951
casr_human 205 N-term R => C missense 8.245e-06 1 121282 0 0.0 0.873
casr_human 205 N-term R => H missense 1.649e-05 2 121282 0 0.03 0.018
casr_human 216 N-term D => N missense 8.245e-06 1 121290 0 0.25 1.0
casr_human 217 N-term D => N missense 1.649e-05 2 121284 0 0.02 0.099
casr_human 227 N-term R => Q missense 8.244e-06 1 121300 0 0.73 0.756
casr_human 235 N-term I => M missense 1.648e-05 2 121344 0 0.04 0.997
casr_human 238 N-term D => N missense 2.472e-05 3 121348 0 0.89 0.01
casr_human 240 N-term S => T missense 1.648e-05 2 121364 0 0.12 0.111
casr_human 247 N-term S => F missense 3.295e-05 4 121394 0 0.7 0.006
casr_human 250 N-term E => K missense 0.001837 223 121396 0 0.21 0.006
casr_human 251 N-term E => G missense 1.648e-05 2 121394 0 0.02 0.16
casr_human 253 N-term Q => K missense 9.061e-05 11 121394 0 0.94 0.002
casr_human 253 N-term Q => L missense 8.238e-06 1 121394 0 0.41 0.068
casr_human 257 N-term E => G missense 8.238e-06 1 121388 0 0.15 0.01
casr_human 258 N-term V => A missense 8.238e-06 1 121384 0 0.11 0.046
casr_human 260 N-term Q => R missense 0.0001236 15 121382 0 0.21 0.186
casr_human 263 N-term T => M missense 8.239e-06 1 121374 0 0.0 0.956
casr_human 263 N-term T => K missense 8.239e-06 1 121374 0 0.03 0.674
casr_human 272 N-term S => G missense 8.243e-06 1 121320 0 0.25 0.057
casr_human 279 N-term L => V missense 8.247e-06 1 121256 0 0.05 0.725
casr_human 282 N-term E => G missense 1.65e-05 2 121238 0 0.0 0.989
casr_human 283 N-term I => T missense 0.000132 16 121230 0 0.0 0.801
casr_human 285 N-term R => P missense 8.25e-06 1 121206 0 0.05 0.468
casr_human 289 N-term T => M missense 8.259e-06 1 121076 0 0.0 1.0
casr_human 291 N-term K => N missense 8.269e-06 1 120930 0 0.31 0.366
casr_human 305 N-term I => V missense 8.261e-06 1 121058 0 0.14 0.217
casr_human 307 N-term M => I missense 2.479e-05 3 121040 0 0.11 0.173
casr_human 308 N-term P => L missense 8.262e-06 1 121042 0 0.02 0.869
casr_human 316 N-term G => S missense 8.265e-06 1 120996 0 0.03 0.52
casr_human 318 N-term I => V missense 8.263e-06 1 121016 0 0.09 0.683
casr_human 324 N-term A => P missense 8.264e-06 1 121012 0 0.09 0.032
casr_human 325 N-term G => R missense 8.264e-06 1 121014 0 0.0 1.0
casr_human 331 N-term R => Q missense 8.264e-06 1 121014 0 0.12 0.805
casr_human 336 N-term K => N missense 1.652e-05 2 121076 0 0.35 0.015 PTM (Acetylation)
casr_human 336 N-term K => N missense 8.259e-06 1 121076 0 0.35 0.015 PTM (Acetylation)
casr_human 337 N-term V => F missense 8.259e-06 1 121080 0 0.0 0.993
casr_human 338 N-term H => R missense 8.258e-06 1 121088 0 0.46 0.068
casr_human 340 N-term R => K missense 1.652e-05 2 121096 0 0.74 0.0
casr_human 343 N-term V => I missense 1.651e-05 2 121146 0 0.18 0.002
casr_human 343 N-term V => A missense 8.254e-06 1 121148 0 0.34 0.001
casr_human 345 N-term N => D missense 8.253e-06 1 121166 0 0.11 0.133
casr_human 360 N-term L => F missense 8.242e-06 1 121328 0 0.6 0.376
casr_human 363 N-term G => S missense 8.241e-06 1 121344 0 0.41 0.002
casr_human 364 N-term A => E missense 1.648e-05 2 121350 0 0.76 0.049
casr_human 366 N-term G => E missense 8.24e-06 1 121358 0 0.12 0.124
casr_human 367 N-term P => S missense 1.648e-05 2 121362 0 0.47 0.003
casr_human 371 N-term D => N missense 8.239e-06 1 121368 0 0.29 0.086
casr_human 372 N-term T => A missense 8.239e-06 1 121370 0 0.43 0.001
casr_human 375 N-term R => K missense 2.472e-05 3 121366 0 0.64 0.001
casr_human 382 N-term D => N missense 3.295e-05 4 121390 0 0.82 0.001
casr_human 387 N-term S => G missense 8.237e-06 1 121402 0 0.37 0.003
casr_human 388 N-term S => W missense 1.647e-05 2 121400 0 0.0 0.868
casr_human 390 N-term A => G missense 8.237e-06 1 121400 0 0.27 0.111
casr_human 398 N-term D => N missense 0.000486 59 121406 0 0.39 0.007
casr_human 398 N-term D => G missense 3.295e-05 4 121406 0 0.24 0.049
casr_human 400 N-term N => I missense 3.295e-05 4 121404 0 0.01 0.951
casr_human 402 N-term S => R missense 8.237e-06 1 121404 0 0.54 0.211
casr_human 403 N-term S => C missense 8.237e-06 1 121404 0 0.01 0.937
casr_human 429 N-term H => Y missense 0.001797 218 121306 2 0.15 0.022
casr_human 429 N-term H => Q missense 2.473e-05 3 121302 0 0.04 0.12
casr_human 433 N-term D => H missense 0.000198 24 121224 0 0.01 0.95
casr_human 433 N-term D => Y missense 8.249e-06 1 121224 0 0.0 0.975
casr_human 445 N-term T => A missense 0.0238 2871 120628 377 0.73 0.017
casr_human 447 N-term G => D missense 8.299e-06 1 120494 0 0.24 0.793
casr_human 451 N-term D => N missense 8.313e-06 1 120298 0 0.45 0.409
casr_human 452 N-term I => V missense 8.317e-06 1 120238 0 0.09 0.78
casr_human 460 N-term V => I missense 8.247e-06 1 121262 0 0.06 0.519
casr_human 463 N-term H => Q missense 4.121e-05 5 121326 0 0.12 0.114
casr_human 464 N-term L => V missense 8.242e-06 1 121330 0 0.02 0.869
casr_human 465 N-term R => W missense 1.648e-05 2 121338 0 0.0 0.939
casr_human 466 N-term H => Y missense 8.24e-06 1 121352 0 0.04 0.934
casr_human 466 N-term H => Q missense 8.24e-06 1 121360 0 0.32 0.905
casr_human 469 N-term F => L missense 8.239e-06 1 121376 0 0.0 0.923
casr_human 471 N-term N => I missense 8.239e-06 1 121380 0 0.05 0.562
casr_human 476 N-term Q => R missense 8.238e-06 1 121396 0 0.31 0.05
casr_human 477 N-term V => A missense 8.238e-06 1 121394 0 0.0 0.78
casr_human 482 N-term C => S missense 8.238e-06 1 121394 0 0.16 0.004
casr_human 482 N-term C => Y missense 8.237e-06 1 121398 0 0.1 0.102
casr_human 486 N-term V => L missense 8.237e-06 1 121400 0 0.64 0.013
casr_human 488 N-term N => S missense 8.237e-06 1 121400 0 0.47 0.531 PTM (N-linked Glycosylation)
casr_human 491 N-term I => V missense 8.237e-06 1 121406 0 0.31 0.824
casr_human 496 N-term L => F missense 8.237e-06 1 121410 0 0.7 0.866
casr_human 503 N-term I => V missense 8.237e-06 1 121408 0 0.93 0.006
casr_human 504 N-term V => M missense 4.118e-05 5 121408 0 0.12 0.004
casr_human 506 N-term K => T missense 8.237e-06 1 121406 0 0.67 0.104
casr_human 509 N-term G => R missense 8.237e-06 1 121408 0 0.0 1.0
casr_human 510 N-term Y => C missense 8.237e-06 1 121408 0 0.11 0.575
casr_human 517 N-term K => E missense 1.648e-05 2 121388 0 0.75 0.217
casr_human 517 N-term K => N missense 1.648e-05 2 121384 0 0.31 0.009
casr_human 518 N-term G => E missense 8.238e-06 1 121382 0 0.06 0.951
casr_human 520 N-term R => S missense 8.241e-06 1 121350 0 0.05 0.392
casr_human 522 N-term F => L missense 8.241e-06 1 121338 0 0.65 0.004
casr_human 522 N-term F => L missense 8.242e-06 1 121324 0 0.65 0.004
casr_human 525 N-term E => K missense 1.649e-05 2 121292 0 0.16 0.024
casr_human 531 N-term S => N missense 8.26e-06 1 121062 0 1.0 0.003
casr_human 535 N-term R => S missense 8.298e-06 1 120516 0 0.24 0.019
casr_human 539 N-term F => L missense 8.237e-06 1 121410 0 0.38 0.013
casr_human 541 N-term N => S missense 8.237e-06 1 121410 0 0.02 0.689
casr_human 544 N-term R => Q missense 0.0007907 96 121410 0 0.06 0.028
casr_human 544 N-term R => L missense 8.237e-06 1 121410 0 0.01 0.064
casr_human 548 N-term A => T missense 1.647e-05 2 121412 0 0.03 0.01
casr_human 555 N-term I => V missense 8.236e-06 1 121412 0 0.16 0.403
casr_human 559 N-term P => L missense 8.237e-06 1 121410 0 0.0 0.876
casr_human 560 N-term T => P missense 8.237e-06 1 121410 0 0.02 0.864
casr_human 592 N-term N => S missense 0.003295 400 121400 8 0.14 0.136
casr_human 594 N-term N => S missense 8.237e-06 1 121402 0 0.16 0.999
casr_human 604 N-term E => D missense 8.237e-06 1 121404 0 0.01 0.671
casr_human 609 N-term T => A missense 8.237e-06 1 121404 0 0.71 0.441
casr_human 609 N-term T => M missense 1.647e-05 2 121402 0 0.1 0.959
casr_human 615 1.42x42 TM1 A => T missense 1.648e-05 2 121396 0 0.39 0.699
casr_human 621 1.48x48 TM1 V => M missense 4.119e-05 5 121392 0 0.03 0.686
casr_human 631 1.58x58 TM1 L => V missense 8.24e-06 1 121358 0 0.15 0.596
casr_human 636 1.63x63 TM1 K => E missense 8.241e-06 1 121350 0 0.23 0.734
casr_human 638 ICL1 R => H missense 2.472e-05 3 121338 0 0.06 0.479
casr_human 648 2.36x36 TM2 R => G missense 8.244e-06 1 121294 0 0.03 0.996
casr_human 648 2.36x36 TM2 R => L missense 3.298e-05 4 121284 0 0.04 0.961
casr_human 671 ECL1 E => V missense 8.249e-06 1 121226 0 0.0 0.677
casr_human 676 3.28x28 TM3 T => M missense 8.25e-06 1 121210 0 0.0 0.149
casr_human 676 3.28x28 TM3 T => R missense 8.25e-06 1 121210 0 0.0 0.524
casr_human 680 3.32x32 TM3 R => C missense 8.25e-06 1 121210 0 0.03 0.999 LB (polar (charge-assisted hydrogen bond))
casr_human 680 3.32x32 TM3 R => H missense 1.65e-05 2 121196 0 0.0 0.998 LB (polar (charge-assisted hydrogen bond))
casr_human 686 3.38x38 TM3 I => V missense 3.299e-05 4 121240 0 0.05 0.034
casr_human 688 3.40x40 TM3 F => C missense 8.247e-06 1 121254 0 0.0 1.0
casr_human 695 3.47x47 TM3 I => V missense 8.246e-06 1 121270 0 0.35 0.557
casr_human 701 3.53x53 TM3 R => C missense 1.649e-05 2 121278 0 0.04 0.365 SodiumPocket MicroSwitch
casr_human 702 3.54x54 TM3 V => I missense 8.246e-06 1 121278 0 0.04 0.155 SodiumPocket MicroSwitch GP (contact)
casr_human 712 ICL2 T => N missense 8.251e-06 1 121192 0 0.26 0.988
casr_human 713 ICL2 S => G missense 8.251e-06 1 121192 0 0.36 0.042
casr_human 716 ICL2 R => H missense 1.652e-05 2 121094 0 0.14 0.999
casr_human 722 4.30x30 TM4 N => K missense 2.479e-05 3 121030 0 0.96 0.843
casr_human 736 4.44x44 TM4 I => T missense 8.27e-06 1 120922 0 0.01 0.446
casr_human 737 4.45x45 TM4 V => I missense 1.654e-05 2 120918 0 0.34 0.006
casr_human 738 4.46x46 TM4 I => T missense 8.272e-06 1 120892 0 0.07 0.057
casr_human 739 4.47x47 TM4 C => Y missense 2.482e-05 3 120892 0 0.0 0.46
casr_human 744 4.52x52 TM4 Y => F missense 8.286e-06 1 120690 0 0.52 0.925
casr_human 746 4.54x54 TM4 A => T missense 1.659e-05 2 120524 0 0.04 0.955
casr_human 746 4.54x54 TM4 A => V missense 4.979e-05 6 120508 0 0.01 0.606
casr_human 749 ECL2 S => A missense 8.303e-06 1 120434 0 0.51 0.038
casr_human 752 ECL2 R => H missense 2.492e-05 3 120386 0 0.0 0.836
casr_human 754 ECL2 Q => R missense 8.304e-06 1 120430 0 0.33 0.049
casr_human 755 ECL2 E => D missense 2.491e-05 3 120434 0 0.33 0.046
casr_human 764 ECL2 T => M missense 8.295e-06 1 120550 0 0.0 0.991
casr_human 766 45.51x51 ECL2 H => Y missense 8.294e-06 1 120568 0 0.11 0.659
casr_human 768 ECL2 G => V missense 4.144e-05 5 120648 0 0.0 0.961
casr_human 772 5.39x39 TM5 A => T missense 8.285e-06 1 120698 0 0.01 0.995
casr_human 779 5.46x46 TM5 Y => H missense 8.28e-06 1 120770 0 0.0 1.0
casr_human 780 5.47x47 TM5 T => I missense 8.277e-06 1 120812 0 1.0 0.974 SodiumPocket MicroSwitch LB (Van der Waals)
casr_human 786 5.53x53 TM5 I => V missense 2.48e-05 3 120964 0 0.64 0.005
casr_human 802 6.34x34 TM6 N => S missense 1.649e-05 2 121312 0 0.0 0.897 GP (contact)
casr_human 804 6.36x36 TM6 A => S missense 1.648e-05 2 121324 0 0.0 0.899 SodiumPocket MicroSwitch
casr_human 813 6.45x45 TM6 I => V missense 2.472e-05 3 121368 0 0.09 0.487
casr_human 819 6.51x51 TM6 I => M missense 8.238e-06 1 121384 0 0.02 0.973
casr_human 825 6.57x57 TM6 Y => C missense 8.237e-06 1 121398 0 0.0 0.998 LB (aromatic (face-to-edge), Van der Waals, hydrophobic, polar (hydrogen bond))
casr_human 850 7.45x46 TM7 A => E missense 8.24e-06 1 121356 0 0.06 0.962
casr_human 851 7.46x47 TM7 C => S missense 1.648e-05 2 121350 0 0.03 1.0
casr_human 857 7.52x52 TM7 I => T missense 8.244e-06 1 121302 0 0.0 0.049
casr_human 858 7.53x53 TM7 Y => D missense 8.244e-06 1 121304 0 0.0 1.0
casr_human 862 7.57x57 TM7 F => S missense 0.0001154 14 121276 0 0.0 0.33
casr_human 880 C-term A => S missense 1.654e-05 2 120944 0 0.11 0.47
casr_human 890 C-term R => C missense 8.302e-06 1 120460 0 nan 0.708
casr_human 890 C-term R => H missense 8.3e-06 1 120476 0 nan 0.708
casr_human 891 C-term R => H missense 1.66e-05 2 120460 0 nan 0.023
casr_human 894 C-term V => F missense 2.49e-05 3 120502 0 nan 0.118
casr_human 896 C-term R => G missense 8.3e-06 1 120480 0 nan 0.994
casr_human 896 C-term R => C missense 8.3e-06 1 120480 0 nan 0.997
casr_human 896 C-term R => L missense 8.299e-06 1 120494 0 nan 0.994
casr_human 898 C-term R => Q missense 3.32e-05 4 120496 0 nan 0.347
casr_human 899 C-term S => P missense 8.296e-06 1 120536 0 nan 0.265 PTM (Phosphorylation)
casr_human 904 C-term G => A missense 8.294e-06 1 120568 0 nan 0.998
casr_human 907 C-term G => A missense 8.292e-06 1 120596 0 nan 0.038
casr_human 908 C-term S => Y missense 8.291e-06 1 120606 0 nan 0.679
casr_human 913 C-term S => F missense 1.657e-05 2 120674 0 nan 0.456
casr_human 920 C-term S => N missense 8.276e-06 1 120832 0 nan 0.085
casr_human 920 C-term S => R missense 1.656e-05 2 120806 0 nan 0.209
casr_human 921 C-term E => K missense 1.655e-05 2 120842 0 nan 0.385
casr_human 922 C-term D => H missense 8.275e-06 1 120844 0 nan 0.914
casr_human 923 C-term P => A missense 2.482e-05 3 120860 0 nan 0.003
casr_human 924 C-term F => L missense 8.273e-06 1 120868 0 nan 0.015
casr_human 926 C-term Q => R missense 0.0001324 16 120880 0 nan 0.002
casr_human 931 C-term K => Q missense 8.278e-06 1 120796 0 nan 0.002
casr_human 937 C-term A => G missense 8.266e-06 1 120984 0 nan 0.01
casr_human 942 C-term E => K missense 0.0008266 100 120980 2 nan 0.014
casr_human 947 C-term P => S missense 8.257e-06 1 121112 0 nan 0.057
casr_human 947 C-term P => L missense 8.256e-06 1 121122 0 nan 0.057
casr_human 948 C-term L => P missense 8.256e-06 1 121130 0 nan 0.001
casr_human 950 C-term L => P missense 3.302e-05 4 121144 0 nan 0.0
casr_human 953 C-term Q => E missense 2.476e-05 3 121178 0 1.0 0.002
casr_human 957 C-term Q => R missense 3.299e-05 4 121246 0 nan 0.041
casr_human 962 C-term C => R missense 8.245e-06 1 121286 0 nan 0.316
casr_human 967 C-term I => V missense 8.243e-06 1 121314 0 nan 0.051
casr_human 972 C-term T => M missense 4.121e-05 5 121326 0 nan 0.124
casr_human 974 C-term T => I missense 2.473e-05 3 121332 0 nan 0.996
casr_human 985 C-term N => T missense 8.242e-06 1 121330 0 nan 0.033
casr_human 986 C-term A => S missense 0.1269 15391 121254 1237 nan 0.012
casr_human 988 C-term A => V missense 1.649e-05 2 121310 0 nan 0.003
casr_human 990 C-term R => G missense 0.1451 17589 121184 2401 nan 0.116
casr_human 993 C-term T => M missense 1.649e-05 2 121284 0 nan 0.002
casr_human 1001 C-term Q => K missense 8.248e-06 1 121244 0 nan 0.012
casr_human 1004 C-term S => R missense 8.246e-06 1 121270 0 nan 0.038
casr_human 1005 C-term D => N missense 3.299e-05 4 121254 0 nan 0.141
casr_human 1005 C-term D => Y missense 8.247e-06 1 121254 0 nan 0.735
casr_human 1006 C-term T => M missense 8.248e-06 1 121246 0 nan 0.195
casr_human 1009 C-term R => Q missense 8.252e-06 1 121188 0 nan 0.077
casr_human 1009 C-term R => L missense 8.252e-06 1 121188 0 nan 0.127
casr_human 1010 C-term H => Y missense 8.249e-06 1 121232 0 nan 0.153
casr_human 1010 C-term H => Q missense 8.253e-06 1 121168 0 nan 0.096
casr_human 1012 C-term P => T missense 8.241e-06 1 121346 0 nan 0.0
casr_human 1013 C-term L => S missense 8.241e-06 1 121344 0 nan 0.997
casr_human 1014 C-term L => I missense 1.648e-05 2 121340 0 nan 0.002
casr_human 1015 C-term P => L missense 8.241e-06 1 121340 0 nan 0.579
casr_human 1016 C-term L => P missense 8.24e-06 1 121354 0 nan 0.999
casr_human 1017 C-term Q => R missense 8.241e-06 1 121350 0 nan 0.008
casr_human 1021 C-term T => K missense 8.242e-06 1 121328 0 nan 0.025
casr_human 1027 C-term V => I missense 8.246e-06 1 121266 0 nan 0.001
casr_human 1027 C-term V => A missense 8.247e-06 1 121256 0 nan 0.0
casr_human 1029 C-term E => D missense 8.251e-06 1 121204 0 nan 0.002
casr_human 1031 C-term G => S missense 0.0002228 27 121160 1 nan 0.002
casr_human 1035 C-term P => S missense 1.652e-05 2 121062 0 nan 0.0
casr_human 1038 C-term G => R missense 8.262e-06 1 121032 0 nan 0.68
casr_human 1041 C-term R => W missense 2.48e-05 3 120984 0 nan 0.292
casr_human 1043 C-term E => V missense 8.268e-06 1 120950 0 nan 0.226
casr_human 1045 C-term E => D missense 8.272e-06 1 120896 0 nan 0.022
casr_human 1048 C-term E => K missense 8.277e-06 1 120818 0 nan 0.031
casr_human 1051 C-term S => P missense 8.286e-06 1 120692 0 nan 0.001
casr_human 1063 C-term V => I missense 8.343e-06 1 119868 0 nan 0.007
casr_human 1065 C-term S => G missense 6.683e-05 8 119708 0 nan 0.08
casr_human 1066 C-term G => D missense 8.366e-06 1 119526 0 nan 0.998
casr_human 1074 C-term N => D missense 8.464e-06 1 118150 0 nan 0.103
casr_human 1075 C-term V => L missense 8.48e-06 1 117926 0 nan 0.002


Residue

Diagrams

ICL1 T R N P I V K A T ICL1ECL1 G E P ECL1ICL2 E A K I P T S F H R K W W ICL2ECL2 P P S S Y R N Q E L E D E I I F I T C H E G S ECL2ICL3 P E N F ICL3ECL3 Y ECL3N-term M A F Y S C C W V L L A L T W H T S A Y G P D Q R A Q K K G D I I L G G L F P I H F G V A A K D Q D L K S R P E S V E C I R Y N F R G F R W L Q A M I F A I E E I N S S P A L L P N L T L G Y R I F D T C N T V S K A L E A T L S F V A Q N K I D S L N L D E F C N C S E H I P S T I A V V G A T G S G V S T A V A N L L G L F Y I P Q V S Y A S S S R L L S N K N Q F K S F L R T I P N D E H Q A T A M A D I I E Y F R W N W V G T I A A D D D Y G R P G I E K F R E E A E E R D I C I D F S E L I S Q Y S D E E E I Q H V V E V I Q N S T A K V I V V F S S G P D L E P L I K E I V R R N I T G K I W L A S E A W A S S S L I A M P Q Y F H V V G G T I G F A L K A G Q I P G F R E F L K K V H P R K S V H N G F A K E F W E E T F N C H L Q E G A K G P L P V D T F L R G H E E S G D R F S N S S T A F R P L C T G D E N I S S V E T P Y I D Y T H L R I S Y N V Y L A V Y S I A H A L Q D I Y T C L P G R G L F T N G S C A D I K K V E A W Q V L K H L R H L N F T N N M G E Q V T F D E C G D L V G N Y S I I N W H L S P E D G S I V F K E V G Y Y N V Y A K K G E R L F I N E E K I L W S G F S R E V P F S N C S R D C L A G T R K G I I E G E P T C C F E C V E C P D G E Y S D E T D A S A C N K C P D D F W S N E N H T S C I A K E I E F L S W T N-termC-term T A A H A F K V A A R A T L R R S N V S R K R S S S L G G S T G S T P S S S I S S K S N S E D P F P Q P E R Q K Q Q Q P L A L T Q Q E Q Q Q Q P L T L P Q Q Q R S Q Q Q P R C K Q K V I F G S G T V T F S L S F D E P Q K N A M A H R N S T H Q N S L E A Q K S S D T L T R H Q P L L P L Q C G E T D L D L T V Q E T G L Q G P V G G D Q R P E V E D P E E L S P A L V V S S S Q S F V I S G G G S T V T E N V V N S C-term E P F G I A L T L F A V L G I F L T A F V L G V F I K F N R E L S Y L L L F S L L C C F S S S L F F I Q D W T C R L R Q P A F G I S F V L C I S C I L V K T N R V L L V F G L N L Q F L L V F L C T F M Q I V I C V I W L Y T A L M A L G F L I G Y T C L L A A I C F F F A F K S R K L N E A K F I T F S M L I F F I V W I S F I P A Y A S T G K F V S A V E V I A I L A A S F G L L A C I F F N K I Y I I L F K P S R E V R N T I E C S
SnakePlot Download: PNG | SVG A T L F I G L V A F L T L A I G F P E 1 Y L L L F S L L C C F S S S L F F I 2 V L I C S I C L V F S I G F A P Q R L R 3 Q F L L V F L C T F M Q I V I C V I W L 4 A F F F C I A A L L C T Y G I L F G L A 5 T F S M L I F F I V W I S F I P A Y A S 6 A L L G F S A A L I A I V E V A S V F K 7
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