FPR2/ALX (fpr2_mouse)
FAMILY
Class A (Rhodopsin) Peptide receptors Formylpeptide receptors FPR2/ALX
GENE
Fpr2 (Fpr-rs2)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Formyl peptide receptor 2, Formylpeptide receptor-related sequence 2, Lipoxin A4 receptor-like protein, N-formylpeptide receptor-like 2
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
E
|
S
|
N
|
Y
|
S
|
I
|
H
|
L
|
N
|
10 |
G
|
S
|
E
|
V
|
V
|
V
|
Y
|
D
|
S
|
T
|
20 |
TM1 | |||||||||
I
|
S
|
R
|
V
|
L
|
W
|
I
|
L
|
S
|
M
|
30 |
V
|
V
|
V
|
S
|
I
|
T
|
F
|
F
|
L
|
G
|
40 |
V
|
L
|
G
|
N
|
G
|
L
|
V
|
I
|
W
|
V
|
50 |
ICL1 | TM2 | ||||||||||
A
|
G
|
F
|
R
|
M
|
P
|
H
|
T
|
V
|
T
|
||
60 |
T
|
I
|
W
|
Y
|
L
|
N
|
L
|
A
|
L
|
A
|
70 |
D
|
F
|
S
|
F
|
T
|
A
|
T
|
L
|
P
|
F
|
80 |
L
|
L
|
V
|
E
|
M
|
A
|
M
|
K
|
E
|
K
|
90 |
ECL1 | TM3 | ||||||||
W
|
P
|
F
|
G
|
W
|
F
|
L
|
C
|
K
|
L
|
100 |
V
|
H
|
I
|
V
|
V
|
D
|
V
|
N
|
L
|
F
|
110 |
G
|
S
|
V
|
F
|
L
|
I
|
A
|
L
|
I
|
A
|
120 |
L
|
D
|
R
|
C
|
I
|
C
|
V
|
L
|
H
|
P
|
130 |
ICL2 | TM4 | ||||||||
V
|
W
|
A
|
Q
|
N
|
H
|
R
|
T
|
V
|
S
|
140 |
L
|
A
|
R
|
K
|
V
|
V
|
V
|
G
|
P
|
W
|
150 |
I
|
F
|
A
|
L
|
I
|
L
|
T
|
L
|
P
|
I
|
160 |
ECL2 | |||||||||
F
|
I
|
F
|
L
|
T
|
T
|
V
|
R
|
I
|
P
|
170 |
G
|
G
|
D
|
V
|
Y
|
C
|
T
|
F
|
N
|
F
|
180 |
TM5 | |||||||||
G
|
S
|
W
|
A
|
Q
|
T
|
D
|
E
|
E
|
K
|
190 |
L
|
N
|
T
|
A
|
I
|
T
|
F
|
V
|
T
|
T
|
200 |
R
|
G
|
I
|
I
|
R
|
F
|
L
|
I
|
G
|
F
|
210 |
S
|
M
|
P
|
M
|
S
|
I
|
V
|
A
|
V
|
C
|
220 |
Y
|
G
|
L
|
I
|
A
|
V
|
K
|
I
|
N
|
R
|
230 |
ICL3 | TM6 | ||||||||
R
|
N
|
L
|
V
|
N
|
S
|
S
|
R
|
P
|
L
|
240 |
R
|
V
|
L
|
T
|
A
|
V
|
V
|
A
|
S
|
F
|
250 |
F
|
I
|
C
|
W
|
F
|
P
|
F
|
Q
|
L
|
V
|
260 |
A
|
L
|
L
|
G
|
T
|
V
|
W
|
F
|
K
|
E
|
270 |
ECL3 | TM7 | ||||||||
T
|
L
|
L
|
S
|
G
|
S
|
Y
|
K
|
I
|
L
|
280 |
D
|
M
|
F
|
V
|
N
|
P
|
T
|
S
|
S
|
L
|
290 |
A
|
Y
|
F
|
N
|
S
|
C
|
L
|
N
|
P
|
M
|
300 |
H8 | |||||||||
L
|
Y
|
V
|
F
|
M
|
G
|
Q
|
D
|
F
|
R
|
310 |
E
|
R
|
F
|
I
|
H
|
S
|
L
|
P
|
Y
|
S
|
320 |
C-term | |||||||||
L
|
E
|
R
|
A
|
L
|
S
|
E
|
D
|
S
|
G
|
330 |
Q
|
T
|
S
|
D
|
S
|
S
|
T
|
S
|
S
|
T
|
340 |
S
|
P
|
P
|
A
|
D
|
I
|
E
|
L
|
K
|
A
|
350 |
P
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
CRAMP
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available