FFA4 receptor (ffar4_rat)
FAMILY
Class A (Rhodopsin) Lipid receptors Free fatty acid receptors FFA4 receptor
GENE
Ffar4 (Gpr120, O3far1)
ORGANISM
Rat (Rattus norvegicus)
ALT. NAMES
Free fatty acid receptor 4, G-protein coupled receptor 120, Omega-3 fatty acid receptor 1
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
S
|
P
|
E
|
C
|
A
|
Q
|
T
|
T
|
G
|
10 |
P
|
G
|
P
|
S
|
R
|
T
|
P
|
D
|
Q
|
V
|
20 |
N
|
R
|
T
|
H
|
F
|
P
|
F
|
F
|
S
|
D
|
30 |
TM1 | |||||||||
V
|
K
|
G
|
D
|
H
|
R
|
L
|
V
|
L
|
S
|
40 |
V
|
L
|
E
|
T
|
T
|
V
|
L
|
G
|
L
|
I
|
50 |
F
|
V
|
V
|
S
|
L
|
L
|
G
|
N
|
V
|
C
|
60 |
A
|
L
|
V
|
L
|
V
|
V
|
R
|
R
|
R
|
R
|
70 |
ICL1 | TM2 | ||||||||
R
|
G
|
A
|
T
|
V
|
S
|
L
|
V
|
L
|
N
|
80 |
L
|
F
|
C
|
A
|
D
|
L
|
L
|
F
|
T
|
S
|
90 |
A
|
I
|
P
|
L
|
V
|
L
|
V
|
V
|
R
|
W
|
100 |
ECL1 | TM3 | ||||||||
T
|
E
|
A
|
W
|
L
|
L
|
G
|
P
|
V
|
V
|
110 |
C
|
H
|
L
|
L
|
F
|
Y
|
V
|
M
|
T
|
M
|
120 |
S
|
G
|
S
|
V
|
T
|
I
|
L
|
T
|
L
|
A
|
130 |
A
|
V
|
S
|
L
|
E
|
R
|
M
|
V
|
C
|
I
|
140 |
ICL2 | |||||||||
V
|
R
|
L
|
R
|
R
|
G
|
L
|
S
|
G
|
P
|
150 |
TM4 | |||||||||
G
|
R
|
R
|
T
|
Q
|
A
|
A
|
L
|
L
|
A
|
160 |
F
|
I
|
W
|
G
|
Y
|
S
|
A
|
L
|
A
|
A
|
170 |
L
|
P
|
L
|
C
|
I
|
L
|
F
|
R
|
V
|
V
|
180 |
ECL2 | |||||||||
P
|
Q
|
R
|
L
|
P
|
G
|
G
|
D
|
Q
|
E
|
190 |
I
|
P
|
I
|
C
|
T
|
L
|
D
|
W
|
P
|
N
|
200 |
TM5 | |||||||||
R
|
I
|
G
|
E
|
I
|
S
|
W
|
D
|
V
|
F
|
210 |
F
|
V
|
T
|
L
|
N
|
F
|
L
|
V
|
P
|
G
|
220 |
L
|
V
|
I
|
V
|
I
|
S
|
Y
|
S
|
K
|
I
|
230 |
L
|
Q
|
I
|
T
|
K
|
A
|
S
|
R
|
K
|
R
|
240 |
ICL3 | TM6 | ||||||||||
L
|
T
|
L
|
S
|
L
|
A
|
Y
|
S
|
E
|
S
|
||
250 |
H
|
Q
|
I
|
R
|
V
|
S
|
Q
|
Q
|
D
|
Y
|
260 |
R
|
L
|
F
|
R
|
T
|
L
|
F
|
L
|
L
|
M
|
270 |
V
|
S
|
F
|
F
|
I
|
M
|
W
|
S
|
P
|
I
|
280 |
I
|
I
|
T
|
I
|
L
|
L
|
I
|
L
|
I
|
Q
|
290 |
ECL3 | |||||||||
N
|
F
|
R
|
Q
|
D
|
L
|
V
|
I
|
W
|
P
|
300 |
TM7 | |||||||||
S
|
L
|
F
|
F
|
W
|
V
|
V
|
A
|
F
|
T
|
310 |
F
|
A
|
N
|
S
|
A
|
L
|
N
|
P
|
I
|
L
|
320 |
H8 | |||||||||
Y
|
N
|
M
|
S
|
L
|
F
|
R
|
S
|
E
|
W
|
330 |
R
|
K
|
I
|
F
|
C
|
C
|
F
|
F
|
F
|
P
|
340 |
C-term | |||||||||
E
|
K
|
G
|
A
|
I
|
F
|
T
|
E
|
T
|
S
|
350 |
I
|
R
|
R
|
N
|
D
|
L
|
S
|
V
|
I
|
S
|
360 |
T
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
α-linolenic acid
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available