B1 receptor (bkrb1_mouse)
FAMILY
Class A (Rhodopsin) Peptide receptors Bradykinin receptors B1 receptor
GENE
Bdkrb1 (Bdkrb)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
B1 bradykinin receptor, B1R, BK-1 receptor
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
A
|
S
|
Q
|
A
|
S
|
L
|
K
|
L
|
Q
|
10 |
P
|
S
|
N
|
Q
|
S
|
Q
|
Q
|
A
|
P
|
P
|
20 |
N
|
I
|
T
|
S
|
C
|
E
|
G
|
A
|
P
|
E
|
30 |
TM1 | |||||||||
A
|
W
|
D
|
L
|
L
|
C
|
R
|
V
|
L
|
P
|
40 |
G
|
F
|
V
|
I
|
T
|
V
|
C
|
F
|
F
|
G
|
50 |
L
|
L
|
G
|
N
|
L
|
L
|
V
|
L
|
S
|
F
|
60 |
ICL1 | |||||||||
F
|
L
|
L
|
P
|
W
|
R
|
R
|
W
|
W
|
Q
|
70 |
TM2 | |||||||||
Q
|
R
|
R
|
Q
|
R
|
L
|
T
|
I
|
A
|
E
|
80 |
I
|
Y
|
L
|
A
|
N
|
L
|
A
|
A
|
S
|
D
|
90 |
L
|
V
|
F
|
V
|
L
|
G
|
L
|
P
|
F
|
W
|
100 |
A
|
E
|
N
|
V
|
G
|
N
|
R
|
F
|
N
|
W
|
110 |
ECL1 | TM3 | ||||||||
P
|
F
|
G
|
S
|
D
|
L
|
C
|
R
|
V
|
V
|
120 |
S
|
G
|
V
|
I
|
K
|
A
|
N
|
L
|
F
|
I
|
130 |
S
|
I
|
F
|
L
|
V
|
V
|
A
|
I
|
S
|
Q
|
140 |
D
|
R
|
Y
|
R
|
L
|
L
|
V
|
Y
|
P
|
M
|
150 |
ICL2 | TM4 | ||||||||
T
|
S
|
W
|
G
|
N
|
R
|
R
|
R
|
R
|
Q
|
160 |
A
|
Q
|
V
|
T
|
C
|
L
|
L
|
I
|
W
|
V
|
170 |
A
|
G
|
G
|
L
|
L
|
S
|
T
|
P
|
T
|
F
|
180 |
ECL2 | |||||||||
L
|
L
|
R
|
S
|
V
|
K
|
V
|
V
|
P
|
D
|
190 |
L
|
N
|
I
|
S
|
A
|
C
|
I
|
L
|
L
|
F
|
200 |
TM5 | |||||||||
P
|
H
|
E
|
A
|
W
|
H
|
F
|
V
|
R
|
M
|
210 |
V
|
E
|
L
|
N
|
V
|
L
|
G
|
F
|
L
|
L
|
220 |
P
|
L
|
A
|
A
|
I
|
L
|
Y
|
F
|
N
|
F
|
230 |
H
|
I
|
L
|
A
|
S
|
L
|
R
|
G
|
Q
|
K
|
240 |
ICL3 | |||||||||
E
|
A
|
S
|
R
|
T
|
R
|
C
|
G
|
G
|
P
|
250 |
TM6 | |||||||||
K
|
D
|
S
|
K
|
T
|
M
|
G
|
L
|
I
|
L
|
260 |
T
|
L
|
V
|
A
|
S
|
F
|
L
|
V
|
C
|
W
|
270 |
A
|
P
|
Y
|
H
|
F
|
F
|
A
|
F
|
L
|
D
|
280 |
ECL3 | |||||||||
F
|
L
|
V
|
Q
|
V
|
R
|
V
|
I
|
Q
|
D
|
290 |
TM7 | |||||||||
C
|
F
|
W
|
K
|
E
|
L
|
T
|
D
|
L
|
G
|
300 |
L
|
Q
|
L
|
A
|
N
|
F
|
F
|
A
|
F
|
V
|
310 |
N
|
S
|
C
|
L
|
N
|
P
|
L
|
I
|
Y
|
V
|
320 |
H8 | |||||||||
F
|
A
|
G
|
R
|
L
|
F
|
K
|
T
|
R
|
V
|
330 |
L
|
G
|
T
|
L
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
bradykinin, [des-Arg9]bradykinin
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available