LPA6 receptor (lpar6_mouse)
FAMILY
Class A (Rhodopsin) Lipid receptors Lysophospholipid (LPA) receptors LPA6 receptor
GENE
Lpar6 (P2ry5, P2y5)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Lysophosphatidic acid receptor 6, LPA receptor 6, LPA-6, Oleoyl-L-alpha-lysophosphatidic acid receptor, P2Y purinoceptor 5, P2Y5, Purinergic receptor 5
SOURCE
SWISSPROT
SEQUENCE
N-term | TM1 | ||||||||
M
|
V
|
S
|
S
|
N
|
G
|
S
|
Q
|
C
|
P
|
10 |
Y
|
D
|
D
|
S
|
F
|
K
|
Y
|
T
|
L
|
Y
|
20 |
G
|
C
|
M
|
F
|
S
|
M
|
V
|
F
|
V
|
L
|
30 |
G
|
L
|
I
|
S
|
N
|
C
|
V
|
A
|
I
|
Y
|
40 |
ICL1 | |||||||||
I
|
F
|
I
|
C
|
A
|
L
|
K
|
V
|
R
|
N
|
50 |
TM2 | |||||||||
E
|
T
|
T
|
T
|
Y
|
M
|
I
|
N
|
L
|
A
|
60 |
M
|
S
|
D
|
L
|
L
|
F
|
V
|
F
|
T
|
L
|
70 |
P
|
F
|
R
|
I
|
F
|
Y
|
F
|
A
|
T
|
R
|
80 |
ECL1 | TM3 | ||||||||
N
|
W
|
P
|
F
|
G
|
D
|
L
|
L
|
C
|
K
|
90 |
I
|
S
|
V
|
M
|
L
|
F
|
Y
|
T
|
N
|
M
|
100 |
Y
|
G
|
S
|
I
|
L
|
F
|
L
|
T
|
C
|
I
|
110 |
S
|
V
|
D
|
R
|
F
|
L
|
A
|
I
|
V
|
Y
|
120 |
ICL2 | |||||||||
P
|
F
|
K
|
S
|
K
|
T
|
L
|
R
|
T
|
K
|
130 |
TM4 | |||||||||
R
|
N
|
A
|
K
|
I
|
V
|
C
|
I
|
A
|
V
|
140 |
W
|
F
|
T
|
V
|
M
|
G
|
G
|
S
|
A
|
P
|
150 |
ECL2 | |||||||||
A
|
V
|
F
|
F
|
Q
|
S
|
T
|
H
|
S
|
Q
|
160 |
G
|
N
|
N
|
T
|
S
|
E
|
A
|
C
|
F
|
E
|
170 |
TM5 | |||||||||
N
|
F
|
P
|
A
|
A
|
T
|
W
|
K
|
T
|
Y
|
180 |
L
|
S
|
R
|
I
|
V
|
I
|
F
|
I
|
E
|
I
|
190 |
V
|
G
|
F
|
F
|
I
|
P
|
L
|
I
|
L
|
N
|
200 |
V
|
T
|
C
|
S
|
S
|
M
|
V
|
L
|
R
|
T
|
210 |
ICL3 | TM6 | |||||||||
L
|
N
|
K
|
P
|
V
|
T
|
L
|
S
|
R
|
S
|
|
220 |
K
|
M
|
N
|
K
|
T
|
K
|
V
|
L
|
K
|
M
|
230 |
I
|
F
|
V
|
H
|
L
|
V
|
I
|
F
|
C
|
F
|
240 |
C
|
F
|
V
|
P
|
Y
|
N
|
I
|
N
|
L
|
I
|
250 |
L
|
Y
|
S
|
L
|
M
|
R
|
T
|
Q
|
T
|
F
|
260 |
ECL3 | TM7 | ||||||||
V
|
N
|
C
|
S
|
V
|
V
|
A
|
A
|
V
|
R
|
270 |
T
|
M
|
Y
|
P
|
I
|
T
|
L
|
C
|
I
|
A
|
280 |
V
|
S
|
N
|
C
|
C
|
F
|
D
|
P
|
I
|
V
|
290 |
H8 | |||||||||
Y
|
Y
|
F
|
T
|
S
|
D
|
T
|
I
|
Q
|
N
|
300 |
S
|
I
|
K
|
M
|
K
|
N
|
W
|
S
|
V
|
R
|
310 |
C-term | |||||||||
R
|
S
|
D
|
S
|
R
|
F
|
S
|
E
|
V
|
Q
|
320 |
G
|
T
|
E
|
N
|
F
|
I
|
Q
|
H
|
N
|
L
|
330 |
Q
|
T
|
L
|
K
|
N
|
K
|
I
|
F
|
D
|
N
|
340 |
E
|
S
|
A
|
I
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
LPA, 1-O-Oleoyl-D-glycerol 3-phosphoric acid, LYSOPHOSPHATIDIC ACID
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available