OR2T12 (o2t12_human)
FAMILY
Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 2 OR2T12
GENE
OR2T12
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Olfactory receptor 2T12, Olfactory receptor OR1-57
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
E
|
M
|
R
|
N
|
T
|
T
|
P
|
D
|
F
|
10 |
I
|
L
|
L
|
G
|
L
|
F
|
N
|
H
|
T
|
R
|
20 |
TM1 | |||||||||
A
|
H
|
Q
|
V
|
L
|
F
|
M
|
M
|
L
|
L
|
30 |
A
|
T
|
V
|
L
|
T
|
S
|
L
|
F
|
S
|
N
|
40 |
A
|
L
|
M
|
I
|
L
|
L
|
I
|
H
|
W
|
D
|
50 |
ICL1 | TM2 | ||||||||
H
|
R
|
L
|
H
|
R
|
P
|
M
|
Y
|
F
|
L
|
60 |
L
|
S
|
Q
|
L
|
S
|
L
|
M
|
D
|
M
|
M
|
70 |
L
|
V
|
S
|
T
|
T
|
V
|
P
|
K
|
M
|
A
|
80 |
ECL1 | |||||||||
A
|
D
|
Y
|
L
|
T
|
G
|
N
|
K
|
A
|
I
|
90 |
TM3 | |||||||||
S
|
R
|
A
|
G
|
C
|
G
|
V
|
Q
|
I
|
F
|
100 |
F
|
L
|
P
|
T
|
L
|
G
|
G
|
G
|
E
|
C
|
110 |
F
|
L
|
L
|
A
|
A
|
M
|
A
|
Y
|
D
|
R
|
120 |
ICL2 | |||||||||
Y
|
A
|
A
|
V
|
C
|
H
|
P
|
L
|
R
|
Y
|
130 |
TM4 | |||||||||
P
|
T
|
L
|
M
|
S
|
W
|
Q
|
L
|
C
|
L
|
140 |
R
|
M
|
T
|
M
|
S
|
S
|
W
|
L
|
L
|
G
|
150 |
A
|
A
|
D
|
G
|
L
|
L
|
Q
|
A
|
V
|
A
|
160 |
ECL2 | |||||||||
T
|
L
|
S
|
F
|
P
|
Y
|
C
|
G
|
A
|
H
|
170 |
E
|
I
|
D
|
H
|
F
|
F
|
C
|
E
|
A
|
P
|
180 |
V
|
L
|
V
|
R
|
L
|
A
|
C
|
A
|
D
|
T
|
190 |
TM5 | |||||||||
S
|
V
|
F
|
E
|
N
|
A
|
M
|
Y
|
I
|
C
|
200 |
C
|
V
|
L
|
M
|
L
|
L
|
V
|
P
|
F
|
S
|
210 |
L
|
I
|
L
|
S
|
S
|
Y
|
G
|
L
|
I
|
L
|
220 |
ICL3 | TM6 | |||||||||||
A
|
A
|
V
|
L
|
L
|
M
|
R
|
S
|
T
|
E
|
|||
230 |
A
|
R
|
K
|
K
|
A
|
F
|
A
|
T
|
C
|
S
|
240 |
S
|
H
|
V
|
A
|
V
|
V
|
G
|
L
|
F
|
Y
|
250 |
G
|
A
|
G
|
I
|
F
|
T
|
Y
|
M
|
R
|
P
|
260 |
ECL3 | TM7 | ||||||||
K
|
S
|
H
|
R
|
S
|
T
|
N
|
H
|
D
|
K
|
270 |
V
|
V
|
S
|
A
|
F
|
Y
|
T
|
M
|
F
|
T
|
280 |
P
|
L
|
L
|
N
|
P
|
L
|
I
|
Y
|
S
|
V
|
290 |
H8 | |||||||||
R
|
N
|
S
|
E
|
V
|
K
|
E
|
A
|
L
|
K
|
300 |
R
|
W
|
L
|
G
|
T
|
C
|
V
|
N
|
L
|
K
|
310 |
H
|
Q
|
Q
|
N
|
E
|
A
|
H
|
R
|
S
|
R
|
320 |
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available