GLP-2 receptor (glp2r_rat)
FAMILY
Class B1 (Secretin) Peptide receptors Glucagon receptor family GLP-2 receptor
GENE
Glp2r
ORGANISM
Rat (Rattus norvegicus)
ALT. NAMES
Glucagon-like peptide 2 receptor, GLP-2 receptor, GLP-2-R, GLP-2R
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
R
|
P
|
Q
|
P
|
S
|
P
|
A
|
V
|
P
|
10 |
S
|
R
|
C
|
R
|
E
|
A
|
P
|
V
|
P
|
R
|
20 |
V
|
R
|
A
|
Q
|
P
|
V
|
G
|
I
|
P
|
E
|
30 |
A
|
Q
|
G
|
P
|
V
|
P
|
L
|
H
|
S
|
Q
|
40 |
Q
|
M
|
R
|
L
|
L
|
W
|
G
|
P
|
G
|
R
|
50 |
P
|
F
|
L
|
A
|
L
|
L
|
L
|
L
|
V
|
S
|
60 |
I
|
K
|
Q
|
V
|
T
|
G
|
S
|
L
|
L
|
K
|
70 |
E
|
T
|
T
|
Q
|
K
|
W
|
A
|
N
|
Y
|
K
|
80 |
E
|
K
|
C
|
L
|
E
|
D
|
L
|
H
|
N
|
R
|
90 |
L
|
S
|
G
|
I
|
F
|
C
|
N
|
G
|
T
|
F
|
100 |
D
|
R
|
Y
|
V
|
C
|
W
|
P
|
H
|
S
|
Y
|
110 |
P
|
G
|
N
|
V
|
S
|
V
|
P
|
C
|
P
|
S
|
120 |
Y
|
L
|
P
|
W
|
W
|
N
|
A
|
E
|
S
|
P
|
130 |
G
|
R
|
A
|
Y
|
R
|
H
|
C
|
L
|
A
|
Q
|
140 |
G
|
T
|
W
|
Q
|
T
|
R
|
E
|
N
|
T
|
T
|
150 |
D
|
I
|
W
|
Q
|
D
|
E
|
S
|
E
|
C
|
S
|
160 |
TM1 | |||||||||
E
|
N
|
H
|
S
|
F
|
R
|
Q
|
N
|
V
|
D
|
170 |
H
|
Y
|
A
|
L
|
L
|
Y
|
T
|
L
|
Q
|
L
|
180 |
M
|
Y
|
T
|
V
|
G
|
Y
|
S
|
V
|
S
|
L
|
190 |
I
|
S
|
L
|
F
|
L
|
A
|
L
|
T
|
L
|
F
|
200 |
ICL1 | TM2 | ||||||||
L
|
F
|
L
|
R
|
K
|
L
|
H
|
C
|
T
|
R
|
210 |
N
|
Y
|
I
|
H
|
M
|
N
|
L
|
F
|
A
|
S
|
220 |
F
|
I
|
L
|
K
|
V
|
L
|
A
|
V
|
L
|
V
|
230 |
K
|
D
|
M
|
V
|
S
|
H
|
N
|
S
|
Y
|
S
|
240 |
ECL1 | |||||||||
K
|
R
|
P
|
D
|
D
|
E
|
S
|
G
|
W
|
M
|
250 |
TM3 | |||||||||
S
|
Y
|
L
|
S
|
E
|
T
|
S
|
V
|
S
|
C
|
260 |
R
|
S
|
V
|
Q
|
V
|
L
|
L
|
H
|
Y
|
F
|
270 |
V
|
G
|
T
|
N
|
H
|
L
|
W
|
L
|
L
|
V
|
280 |
E
|
G
|
L
|
Y
|
L
|
H
|
T
|
L
|
L
|
E
|
290 |
ICL2 | |||||||||
P
|
T
|
V
|
F
|
P
|
E
|
R
|
R
|
L
|
W
|
300 |
TM4 | |||||||||
P
|
K
|
Y
|
L
|
V
|
V
|
G
|
W
|
A
|
F
|
310 |
P
|
M
|
L
|
F
|
V
|
I
|
P
|
W
|
G
|
F
|
320 |
ECL2 | |||||||||
A
|
R
|
A
|
H
|
L
|
E
|
N
|
T
|
R
|
C
|
330 |
TM5 | |||||||||
W
|
A
|
T
|
N
|
G
|
N
|
L
|
K
|
I
|
W
|
340 |
W
|
I
|
I
|
R
|
G
|
P
|
M
|
L
|
L
|
C
|
350 |
V
|
T
|
V
|
N
|
F
|
F
|
I
|
F
|
L
|
K
|
360 |
I
|
L
|
K
|
L
|
L
|
I
|
S
|
K
|
L
|
K
|
370 |
ICL3 | TM6 | ||||||||
A
|
H
|
Q
|
M
|
C
|
F
|
R
|
D
|
Y
|
K
|
380 |
Y
|
R
|
L
|
A
|
K
|
S
|
T
|
L
|
L
|
L
|
390 |
I
|
P
|
L
|
L
|
G
|
V
|
H
|
E
|
V
|
L
|
400 |
ECL3 | |||||||||
F
|
T
|
F
|
F
|
P
|
D
|
D
|
Q
|
V
|
Q
|
410 |
TM7 | |||||||||
G
|
F
|
S
|
K
|
R
|
I
|
R
|
L
|
F
|
I
|
420 |
Q
|
L
|
T
|
L
|
S
|
S
|
V
|
H
|
G
|
F
|
430 |
L
|
V
|
A
|
L
|
Q
|
Y
|
G
|
F
|
A
|
N
|
440 |
H8 | |||||||||
G
|
E
|
V
|
K
|
A
|
E
|
L
|
R
|
K
|
S
|
450 |
W
|
G
|
R
|
F
|
L
|
L
|
A
|
R
|
H
|
W
|
460 |
G
|
C
|
R
|
T
|
C
|
V
|
L
|
G
|
K
|
N
|
470 |
C-term | |||||||||
F
|
R
|
F
|
L
|
G
|
K
|
C
|
S
|
K
|
K
|
480 |
L
|
S
|
E
|
G
|
D
|
G
|
S
|
E
|
T
|
L
|
490 |
Q
|
K
|
L
|
R
|
F
|
S
|
T
|
C
|
S
|
S
|
500 |
H
|
L
|
A
|
S
|
E
|
T
|
L
|
G
|
D
|
V
|
510 |
G
|
V
|
Q
|
P
|
H
|
R
|
G
|
R
|
G
|
A
|
520 |
W
|
P
|
R
|
G
|
S
|
S
|
L
|
S
|
E
|
S
|
530 |
S
|
E
|
G
|
D
|
F
|
T
|
L
|
A
|
N
|
T
|
540 |
M
|
E
|
E
|
I
|
L
|
E
|
E
|
S
|
E
|
I
|
550 |
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
glucagon-like peptide 2-(3-33), glucagon-like peptide 2, glucagon-like peptide 2-(2-33)
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available