ADGRF4 (agrf4_human)
FAMILY
Class B2 (Adhesion) Adhesion receptors ADGRF ADGRF4
GENE
ADGRF4 (GPR115, PGR18)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Adhesion G protein-coupled receptor F4, G-protein coupled receptor 115, G-protein coupled receptor PGR18
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
K
|
M
|
K
|
S
|
Q
|
A
|
T
|
M
|
I
|
10 |
C
|
C
|
L
|
V
|
F
|
F
|
L
|
S
|
T
|
E
|
20 |
C
|
S
|
H
|
Y
|
R
|
S
|
K
|
I
|
H
|
L
|
30 |
K
|
A
|
G
|
D
|
K
|
L
|
Q
|
S
|
P
|
E
|
40 |
G
|
K
|
P
|
K
|
T
|
G
|
R
|
I
|
Q
|
E
|
50 |
K
|
C
|
E
|
G
|
P
|
C
|
I
|
S
|
S
|
S
|
60 |
N
|
C
|
S
|
Q
|
P
|
C
|
A
|
K
|
D
|
F
|
70 |
H
|
G
|
E
|
I
|
G
|
F
|
T
|
C
|
N
|
Q
|
80 |
K
|
K
|
W
|
Q
|
K
|
S
|
A
|
E
|
T
|
C
|
90 |
T
|
S
|
L
|
S
|
V
|
E
|
K
|
L
|
F
|
K
|
100 |
D
|
S
|
T
|
G
|
A
|
S
|
R
|
L
|
S
|
V
|
110 |
A
|
A
|
P
|
S
|
I
|
P
|
L
|
H
|
I
|
L
|
120 |
D
|
F
|
R
|
A
|
P
|
E
|
T
|
I
|
E
|
S
|
130 |
V
|
A
|
Q
|
G
|
I
|
R
|
K
|
N
|
C
|
P
|
140 |
F
|
D
|
Y
|
A
|
C
|
I
|
T
|
D
|
M
|
V
|
150 |
K
|
S
|
S
|
E
|
T
|
T
|
S
|
G
|
N
|
I
|
160 |
A
|
F
|
I
|
V
|
E
|
L
|
L
|
K
|
N
|
I
|
170 |
S
|
T
|
D
|
L
|
S
|
D
|
N
|
V
|
T
|
R
|
180 |
E
|
K
|
M
|
K
|
S
|
Y
|
S
|
E
|
V
|
A
|
190 |
N
|
H
|
I
|
L
|
D
|
T
|
A
|
A
|
I
|
S
|
200 |
N
|
W
|
A
|
F
|
I
|
P
|
N
|
K
|
N
|
A
|
210 |
S
|
S
|
D
|
L
|
L
|
Q
|
S
|
V
|
N
|
L
|
220 |
F
|
A
|
R
|
Q
|
L
|
H
|
I
|
H
|
N
|
N
|
230 |
S
|
E
|
N
|
I
|
V
|
N
|
E
|
L
|
F
|
I
|
240 |
Q
|
T
|
K
|
G
|
F
|
H
|
I
|
N
|
H
|
N
|
250 |
T
|
S
|
E
|
K
|
S
|
L
|
N
|
F
|
S
|
M
|
260 |
S
|
M
|
N
|
N
|
T
|
T
|
E
|
D
|
I
|
L
|
270 |
G
|
M
|
V
|
Q
|
I
|
P
|
R
|
Q
|
E
|
L
|
280 |
R
|
K
|
L
|
W
|
P
|
N
|
A
|
S
|
Q
|
A
|
290 |
I
|
S
|
I
|
A
|
F
|
P
|
T
|
L
|
G
|
A
|
300 |
I
|
L
|
R
|
E
|
A
|
H
|
L
|
Q
|
N
|
V
|
310 |
S
|
L
|
P
|
R
|
Q
|
V
|
N
|
G
|
L
|
V
|
320 |
L
|
S
|
V
|
V
|
L
|
P
|
E
|
R
|
L
|
Q
|
330 |
E
|
I
|
I
|
L
|
T
|
F
|
E
|
K
|
I
|
N
|
340 |
K
|
T
|
R
|
N
|
A
|
R
|
A
|
Q
|
C
|
V
|
350 |
G
|
W
|
H
|
S
|
K
|
K
|
R
|
R
|
W
|
D
|
360 |
E
|
K
|
A
|
C
|
Q
|
M
|
M
|
L
|
D
|
I
|
370 |
R
|
N
|
E
|
V
|
K
|
C
|
R
|
C
|
N
|
Y
|
380 |
T
|
S
|
V
|
V
|
M
|
S
|
F
|
S
|
I
|
L
|
390 |
TM1 | |||||||||
M
|
S
|
S
|
K
|
S
|
M
|
T
|
D
|
K
|
V
|
400 |
L
|
D
|
Y
|
I
|
T
|
C
|
I
|
G
|
L
|
S
|
410 |
V
|
S
|
I
|
L
|
S
|
L
|
V
|
L
|
C
|
L
|
420 |
I
|
I
|
E
|
A
|
T
|
V
|
W
|
S
|
R
|
V
|
430 |
ICL1 | TM2 | ||||||||
V
|
V
|
T
|
E
|
I
|
S
|
Y
|
M
|
R
|
H
|
440 |
V
|
C
|
I
|
V
|
N
|
I
|
A
|
V
|
S
|
L
|
450 |
L
|
T
|
A
|
N
|
V
|
W
|
F
|
I
|
I
|
G
|
460 |
ECL1 | |||||||||
S
|
H
|
F
|
N
|
I
|
K
|
A
|
Q
|
D
|
Y
|
470 |
TM3 | |||||||||
N
|
M
|
C
|
V
|
A
|
V
|
T
|
F
|
F
|
S
|
480 |
H
|
F
|
F
|
Y
|
L
|
S
|
L
|
F
|
F
|
W
|
490 |
M
|
L
|
F
|
K
|
A
|
L
|
L
|
I
|
I
|
Y
|
500 |
ICL2 | |||||||||
G
|
I
|
L
|
V
|
I
|
F
|
R
|
R
|
M
|
M
|
510 |
TM4 | |||||||||
K
|
S
|
R
|
M
|
M
|
V
|
I
|
G
|
F
|
A
|
520 |
I
|
G
|
Y
|
G
|
C
|
P
|
L
|
I
|
I
|
A
|
530 |
V
|
T
|
T
|
V
|
A
|
I
|
T
|
E
|
P
|
E
|
540 |
ECL2 | |||||||||
K
|
G
|
Y
|
M
|
R
|
P
|
E
|
A
|
C
|
W
|
550 |
TM5 | |||||||||
L
|
N
|
W
|
D
|
N
|
T
|
K
|
A
|
L
|
L
|
560 |
A
|
F
|
A
|
I
|
P
|
A
|
F
|
V
|
I
|
V
|
570 |
A
|
V
|
N
|
L
|
I
|
V
|
V
|
L
|
V
|
V
|
580 |
ICL3 | |||||||||
A
|
V
|
N
|
T
|
Q
|
R
|
P
|
S
|
I
|
G
|
590 |
S
|
S
|
K
|
S
|
Q
|
D
|
V
|
V
|
I
|
I
|
600 |
TM6 | |||||||||
M
|
R
|
I
|
S
|
K
|
N
|
V
|
A
|
I
|
L
|
610 |
T
|
P
|
L
|
L
|
G
|
L
|
T
|
W
|
G
|
F
|
620 |
G
|
I
|
A
|
T
|
L
|
I
|
E
|
G
|
T
|
S
|
630 |
TM7 | |||||||||
L
|
T
|
F
|
H
|
I
|
I
|
F
|
A
|
L
|
L
|
640 |
N
|
A
|
F
|
Q
|
G
|
F
|
F
|
I
|
L
|
L
|
650 |
H8 | |||||||||
F
|
G
|
T
|
I
|
M
|
D
|
H
|
K
|
I
|
R
|
660 |
D
|
A
|
L
|
R
|
M
|
R
|
M
|
S
|
S
|
L
|
670 |
C-term | |||||||||
K
|
G
|
K
|
S
|
R
|
A
|
A
|
E
|
N
|
A
|
680 |
S
|
L
|
G
|
P
|
T
|
N
|
G
|
S
|
K
|
L
|
690 |
M
|
N
|
R
|
Q
|
G
|