ADGRF5 (agrf5_human)
FAMILY
Class B2 (Adhesion) Adhesion receptors ADGRF ADGRF5
GENE
ADGRF5 (GPR116, KIAA0758)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Adhesion G protein-coupled receptor F5, G-protein coupled receptor 116
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
K
|
S
|
P
|
R
|
R
|
T
|
T
|
L
|
C
|
10 |
L
|
M
|
F
|
I
|
V
|
I
|
Y
|
S
|
S
|
K
|
20 |
A
|
A
|
L
|
N
|
W
|
N
|
Y
|
E
|
S
|
T
|
30 |
I
|
H
|
P
|
L
|
S
|
L
|
H
|
E
|
H
|
E
|
40 |
P
|
A
|
G
|
E
|
E
|
A
|
L
|
R
|
Q
|
K
|
50 |
R
|
A
|
V
|
A
|
T
|
K
|
S
|
P
|
T
|
A
|
60 |
E
|
E
|
Y
|
T
|
V
|
N
|
I
|
E
|
I
|
S
|
70 |
F
|
E
|
N
|
A
|
S
|
F
|
L
|
D
|
P
|
I
|
80 |
K
|
A
|
Y
|
L
|
N
|
S
|
L
|
S
|
F
|
P
|
90 |
I
|
H
|
G
|
N
|
N
|
T
|
D
|
Q
|
I
|
T
|
100 |
D
|
I
|
L
|
S
|
I
|
N
|
V
|
T
|
T
|
V
|
110 |
C
|
R
|
P
|
A
|
G
|
N
|
E
|
I
|
W
|
C
|
120 |
S
|
C
|
E
|
T
|
G
|
Y
|
G
|
W
|
P
|
R
|
130 |
E
|
R
|
C
|
L
|
H
|
N
|
L
|
I
|
C
|
Q
|
140 |
E
|
R
|
D
|
V
|
F
|
L
|
P
|
G
|
H
|
H
|
150 |
C
|
S
|
C
|
L
|
K
|
E
|
L
|
P
|
P
|
N
|
160 |
G
|
P
|
F
|
C
|
L
|
L
|
Q
|
E
|
D
|
V
|
170 |
T
|
L
|
N
|
M
|
R
|
V
|
R
|
L
|
N
|
V
|
180 |
G
|
F
|
Q
|
E
|
D
|
L
|
M
|
N
|
T
|
S
|
190 |
S
|
A
|
L
|
Y
|
R
|
S
|
Y
|
K
|
T
|
D
|
200 |
L
|
E
|
T
|
A
|
F
|
R
|
K
|
G
|
Y
|
G
|
210 |
I
|
L
|
P
|
G
|
F
|
K
|
G
|
V
|
T
|
V
|
220 |
T
|
G
|
F
|
K
|
S
|
G
|
S
|
V
|
V
|
V
|
230 |
T
|
Y
|
E
|
V
|
K
|
T
|
T
|
P
|
P
|
S
|
240 |
L
|
E
|
L
|
I
|
H
|
K
|
A
|
N
|
E
|
Q
|
250 |
V
|
V
|
Q
|
S
|
L
|
N
|
Q
|
T
|
Y
|
K
|
260 |
M
|
D
|
Y
|
N
|
S
|
F
|
Q
|
A
|
V
|
T
|
270 |
I
|
N
|
E
|
S
|
N
|
F
|
F
|
V
|
T
|
P
|
280 |
E
|
I
|
I
|
F
|
E
|
G
|
D
|
T
|
V
|
S
|
290 |
L
|
V
|
C
|
E
|
K
|
E
|
V
|
L
|
S
|
S
|
300 |
N
|
V
|
S
|
W
|
R
|
Y
|
E
|
E
|
Q
|
Q
|
310 |
L
|
E
|
I
|
Q
|
N
|
S
|
S
|
R
|
F
|
S
|
320 |
I
|
Y
|
T
|
A
|
L
|
F
|
N
|
N
|
M
|
T
|
330 |
S
|
V
|
S
|
K
|
L
|
T
|
I
|
H
|
N
|
I
|
340 |
T
|
P
|
G
|
D
|
A
|
G
|
E
|
Y
|
V
|
C
|
350 |
K
|
L
|
I
|
L
|
D
|
I
|
F
|
E
|
Y
|
E
|
360 |
C
|
K
|
K
|
K
|
I
|
D
|
V
|
M
|
P
|
I
|
370 |
Q
|
I
|
L
|
A
|
N
|
E
|
E
|
M
|
K
|
V
|
380 |
M
|
C
|
D
|
N
|
N
|
P
|
V
|
S
|
L
|
N
|
390 |
C
|
C
|
S
|
Q
|
G
|
N
|
V
|
N
|
W
|
S
|
400 |
K
|
V
|
E
|
W
|
K
|
Q
|
E
|
G
|
K
|
I
|
410 |
N
|
I
|
P
|
G
|
T
|
P
|
E
|
T
|
D
|
I
|
420 |
D
|
S
|
S
|
C
|
S
|
R
|
Y
|
T
|
L
|
K
|
430 |
A
|
D
|
G
|
T
|
Q
|
C
|
P
|
S
|
G
|
S
|
440 |
S
|
G
|
T
|
T
|
V
|
I
|
Y
|
T
|
C
|
E
|
450 |
F
|
I
|
S
|
A
|
Y
|
G
|
A
|
R
|
G
|
S
|
460 |
A
|
N
|
I
|
K
|
V
|
T
|
F
|
I
|
S
|
V
|
470 |
A
|
N
|
L
|
T
|
I
|
T
|
P
|
D
|
P
|
I
|
480 |
S
|
V
|
S
|
E
|
G
|
Q
|
N
|
F
|
S
|
I
|
490 |
K
|
C
|
I
|
S
|
D
|
V
|
S
|
N
|
Y
|
D
|
500 |
E
|
V
|
Y
|
W
|
N
|
T
|
S
|
A
|
G
|
I
|
510 |
K
|
I
|
Y
|
Q
|
R
|
F
|
Y
|
T
|
T
|
R
|
520 |
R
|
Y
|
L
|
D
|
G
|
A
|
E
|
S
|
V
|
L
|
530 |
T
|
V
|
K
|
T
|
S
|
T
|
R
|
E
|
W
|
N
|
540 |
G
|
T
|
Y
|
H
|
C
|
I
|
F
|
R
|
Y
|
K
|
550 |
N
|
S
|
Y
|
S
|
I
|
A
|
T
|
K
|
D
|
V
|
560 |
I
|
V
|
H
|
P
|
L
|
P
|
L
|
K
|
L
|
N
|
570 |
I
|
M
|
V
|
D
|
P
|
L
|
E
|
A
|
T
|
V
|
580 |
S
|
C
|
S
|
G
|
S
|
H
|
H
|
I
|
K
|
C
|
590 |
C
|
I
|
E
|
E
|
D
|
G
|
D
|
Y
|
K
|
V
|
600 |
T
|
F
|
H
|
T
|
G
|
S
|
S
|
S
|
L
|
P
|
610 |
A
|
A
|
K
|
E
|
V
|
N
|
K
|
K
|
Q
|
V
|
620 |
C
|
Y
|
K
|
H
|
N
|
F
|
N
|
A
|
S
|
S
|
630 |
V
|
S
|
W
|
C
|
S
|
K
|
T
|
V
|
D
|
V
|
640 |
C
|
C
|
H
|
F
|
T
|
N
|
A
|
A
|
N
|
N
|
650 |
S
|
V
|
W
|
S
|
P
|
S
|
M
|
K
|
L
|
N
|
660 |
L
|
V
|
P
|
G
|
E
|
N
|
I
|
T
|
C
|
Q
|
670 |
D
|
P
|
V
|
I
|
G
|
V
|
G
|
E
|
P
|
G
|
680 |
K
|
V
|
I
|
Q
|
K
|
L
|
C
|
R
|
F
|
S
|
690 |
N
|
V
|
P
|
S
|
S
|
P
|
E
|
S
|
P
|
I
|
700 |
G
|
G
|
T
|
I
|
T
|
Y
|
K
|
C
|
V
|
G
|
710 |
S
|
Q
|
W
|
E
|
E
|
K
|
R
|
N
|
D
|
C
|
720 |
I
|
S
|
A
|
P
|
I
|
N
|
S
|
L
|
L
|
Q
|
730 |
M
|
A
|
K
|
A
|
L
|
I
|
K
|
S
|
P
|
S
|
740 |
Q
|
D
|
E
|
M
|
L
|
P
|
T
|
Y
|
L
|
K
|
750 |
D
|
L
|
S
|
I
|
S
|
I
|
D
|
K
|
A
|
E
|
760 |
H
|
E
|
I
|
S
|
S
|
S
|
P
|
G
|
S
|
L
|
770 |
G
|
A
|
I
|
I
|
N
|
I
|
L
|
D
|
L
|
L
|
780 |
S
|
T
|
V
|
P
|
T
|
Q
|
V
|
N
|
S
|
E
|
790 |
M
|
M
|
T
|
H
|
V
|
L
|
S
|
T
|
V
|
N
|
800 |
V
|
I
|
L
|
G
|
K
|
P
|
V
|
L
|
N
|
T
|
810 |
W
|
K
|
V
|
L
|
Q
|
Q
|
Q
|
W
|
T
|
N
|
820 |
Q
|
S
|
S
|
Q
|
L
|
L
|
H
|
S
|
V
|
E
|
830 |
R
|
F
|
S
|
Q
|
A
|
L
|
Q
|
S
|
G
|
D
|
840 |
S
|
P
|
P
|
L
|
S
|
F
|
S
|
Q
|
T
|
N
|
850 |
V
|
Q
|
M
|
S
|
S
|
M
|
V
|
I
|
K
|
S
|
860 |
S
|
H
|
P
|
E
|
T
|
Y
|
Q
|
Q
|
R
|
F
|
870 |
V
|
F
|
P
|
Y
|
F
|
D
|
L
|
W
|
G
|
N
|
880 |
V
|
V
|
I
|
D
|
K
|
S
|
Y
|
L
|
E
|
N
|
890 |
L
|
Q
|
S
|
D
|
S
|
S
|
I
|
V
|
T
|
M
|
900 |
A
|
F
|
P
|
T
|
L
|
Q
|
A
|
I
|
L
|
A
|
910 |
Q
|
D
|
I
|
Q
|
E
|
N
|
N
|
F
|
A
|
E
|
920 |
S
|
L
|
V
|
M
|
T
|
T
|
T
|
V
|
S
|
H
|
930 |
N
|
T
|
T
|
M
|
P
|
F
|
R
|
I
|
S
|
M
|
940 |
T
|
F
|
K
|
N
|
N
|
S
|
P
|
S
|
G
|
G
|
950 |
E
|
T
|
K
|
C
|
V
|
F
|
W
|
N
|
F
|
R
|
960 |
L
|
A
|
N
|
N
|
T
|
G
|
G
|
W
|
D
|
S
|
970 |
S
|
G
|
C
|
Y
|
V
|
E
|
E
|
G
|
D
|
G
|
980 |
D
|
N
|
V
|
T
|
C
|
I
|
C
|
D
|
H
|
L
|
990 |
T
|
S
|
F
|
S
|
I
|
L
|
M
|
S
|
P
|
D
|
1000 |
TM1 | |||||||||
S
|
P
|
D
|
P
|
S
|
S
|
L
|
L
|
G
|
I
|
1010 |
L
|
L
|
D
|
I
|
I
|
S
|
Y
|
V
|
G
|
V
|
1020 |
G
|
F
|
S
|
I
|
L
|
S
|
L
|
A
|
A
|
C
|
1030 |
L
|