ADGRG5 (agrg5_mouse)
FAMILY
Class B2 (Adhesion) Adhesion receptors ADGRG ADGRG5
GENE
Adgrg5 (Gm1109, Gpr114, Pgr27)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Adhesion G-protein coupled receptor G5, G-protein coupled receptor 114, G-protein coupled receptor PGR27
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
D
|
P
|
H
|
G
|
A
|
L
|
F
|
F
|
Y
|
10 |
L
|
C
|
L
|
L
|
A
|
A
|
Q
|
V
|
V
|
L
|
20 |
V
|
E
|
T
|
L
|
S
|
D
|
L
|
L
|
V
|
L
|
30 |
M
|
K
|
R
|
L
|
E
|
Q
|
P
|
V
|
G
|
R
|
40 |
G
|
L
|
S
|
S
|
R
|
A
|
R
|
H
|
I
|
H
|
50 |
S
|
L
|
E
|
Q
|
K
|
L
|
L
|
N
|
A
|
S
|
60 |
F
|
G
|
G
|
H
|
N
|
L
|
T
|
L
|
Q
|
T
|
70 |
N
|
S
|
I
|
Q
|
S
|
L
|
V
|
F
|
K
|
L
|
80 |
S
|
C
|
D
|
F
|
P
|
G
|
L
|
S
|
L
|
S
|
90 |
S
|
T
|
T
|
L
|
T
|
N
|
V
|
S
|
Q
|
V
|
100 |
R
|
A
|
P
|
H
|
A
|
M
|
Q
|
F
|
P
|
A
|
110 |
E
|
L
|
T
|
K
|
G
|
A
|
C
|
V
|
T
|
S
|
120 |
R
|
P
|
A
|
E
|
L
|
R
|
L
|
I
|
C
|
I
|
130 |
Y
|
F
|
F
|
T
|
A
|
H
|
L
|
F
|
Q
|
D
|
140 |
D
|
R
|
N
|
S
|
S
|
L
|
L
|
N
|
N
|
Y
|
150 |
V
|
L
|
G
|
A
|
Q
|
L
|
D
|
H
|
R
|
P
|
160 |
V
|
N
|
N
|
L
|
Q
|
K
|
P
|
V
|
N
|
I
|
170 |
S
|
F
|
W
|
H
|
N
|
R
|
S
|
L
|
E
|
G
|
180 |
Y
|
T
|
V
|
S
|
C
|
V
|
F
|
W
|
K
|
E
|
190 |
G
|
A
|
S
|
K
|
S
|
S
|
W
|
G
|
A
|
W
|
200 |
S
|
P
|
E
|
G
|
C
|
Y
|
T
|
E
|
Q
|
P
|
210 |
S
|
A
|
T
|
Q
|
V
|
L
|
C
|
H
|
C
|
N
|
220 |
H
|
L
|
T
|
Y
|
F
|
A
|
V
|
L
|
M
|
Q
|
230 |
TM1 | |||||||||
L
|
S
|
G
|
D
|
P
|
V
|
P
|
A
|
E
|
L
|
240 |
Q
|
V
|
P
|
L
|
E
|
Y
|
I
|
S
|
F
|
V
|
250 |
G
|
C
|
S
|
I
|
S
|
I
|
V
|
A
|
S
|
L
|
260 |
L
|
T
|
I
|
L
|
L
|
Y
|
A
|
Q
|
S
|
R
|
270 |
ICL1 | TM2 | ||||||||
K
|
Q
|
S
|
D
|
S
|
T
|
T
|
R
|
I
|
H
|
280 |
M
|
N
|
L
|
N
|
G
|
S
|
V
|
L
|
L
|
L
|
290 |
N
|
V
|
T
|
F
|
L
|
L
|
S
|
S
|
Q
|
M
|
300 |
ECL1 | TM3 | ||||||||
T
|
L
|
P
|
T
|
M
|
P
|
R
|
P
|
V
|
C
|
310 |
K
|
V
|
L
|
A
|
A
|
V
|
L
|
H
|
Y
|
A
|
320 |
L
|
L
|
S
|
S
|
L
|
T
|
W
|
M
|
A
|
I
|
330 |
E
|
G
|
F
|
N
|
L
|
Y
|
L
|
F
|
L
|
G
|
340 |
ICL2 | |||||||||
R
|
V
|
Y
|
N
|
A
|
Y
|
I
|
R
|
R
|
Y
|
350 |
TM4 | |||||||||
L
|
L
|
K
|
L
|
C
|
M
|
L
|
G
|
W
|
G
|
360 |
F
|
P
|
A
|
L
|
L
|
V
|
L
|
L
|
L
|
L
|
370 |
ECL2 | |||||||||
M
|
I
|
K
|
S
|
S
|
V
|
Y
|
G
|
P
|
C
|
380 |
V
|
T
|
S
|
L
|
S
|
K
|
S
|
Q
|
E
|
N
|
390 |
G
|
T
|
G
|
F
|
Q
|
N
|
V
|
S
|
M
|
C
|
400 |
TM5 | |||||||||
W
|
I
|
R
|
S
|
P
|
M
|
V
|
H
|
S
|
I
|
410 |
L
|
V
|
M
|
G
|
Y
|
G
|
G
|
F
|
T
|
S
|
420 |
L
|
F
|
N
|
L
|
V
|
V
|
L
|
A
|
W
|
A
|
430 |
L
|
W
|
I
|
L
|
C
|
R
|
L
|
R
|
A
|
R
|
440 |
ICL3 | TM6 | ||||||||
E
|
K
|
A
|
L
|
S
|
P
|
W
|
A
|
Y
|
R
|
450 |
D
|
T
|
A
|
M
|
V
|
L
|
G
|
L
|
T
|
V
|
460 |
L
|
L
|
G
|
T
|
T
|
W
|
T
|
L
|
A
|
F
|
470 |
ECL3 | TM7 | |||||||||
F
|
S
|
F
|
G
|
V
|
F
|
L
|
L
|
P
|
Q
|
|
480 |
L
|
F
|
L
|
F
|
T
|
I
|
F
|
N
|
S
|
L
|
490 |
Y
|
G
|
F
|
F
|
L
|
F
|
L
|
W
|
F
|
C
|
500 |
H8 | |||||||||
S
|
Q
|
K
|
R
|
Y
|
S
|
D
|
A
|
E
|
A
|
510 |
K
|
A
|
E
|
M
|
E
|
A
|
V
|
S
|
S
|
S
|
520 |
C-term | |||||
Q
|
M
|
T
|
H
|
||
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
ENDOGENOUS LIGANDS
No endogenous ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available