C3a receptor (c3ar_rat)
FAMILY
Class A (Rhodopsin) Peptide receptors Complement peptide receptors C3a receptor
GENE
C3ar1
ORGANISM
Rat (Rattus norvegicus)
ALT. NAMES
C3a anaphylatoxin chemotactic receptor, C3AR, C3a-R
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
E
|
S
|
F
|
T
|
A
|
D
|
T
|
N
|
S
|
10 |
T
|
D
|
L
|
H
|
S
|
R
|
P
|
L
|
F
|
K
|
20 |
TM1 | |||||||||
P
|
Q
|
D
|
I
|
A
|
S
|
M
|
V
|
I
|
L
|
30 |
S
|
L
|
T
|
C
|
L
|
L
|
G
|
L
|
P
|
G
|
40 |
N
|
G
|
L
|
V
|
L
|
W
|
V
|
A
|
G
|
V
|
50 |
ICL1 | TM2 | ||||||||
K
|
M
|
K
|
R
|
T
|
V
|
N
|
T
|
V
|
W
|
60 |
F
|
L
|
H
|
L
|
T
|
L
|
A
|
D
|
F
|
L
|
70 |
C
|
C
|
L
|
S
|
L
|
P
|
F
|
S
|
V
|
A
|
80 |
ECL1 | |||||||||
H
|
L
|
I
|
L
|
R
|
G
|
H
|
W
|
P
|
Y
|
90 |
TM3 | |||||||||
G
|
L
|
F
|
L
|
C
|
K
|
L
|
I
|
P
|
S
|
100 |
V
|
I
|
I
|
L
|
N
|
M
|
F
|
A
|
S
|
V
|
110 |
F
|
L
|
L
|
T
|
A
|
I
|
S
|
L
|
D
|
R
|
120 |
ICL2 | |||||||||
C
|
L
|
M
|
V
|
H
|
K
|
P
|
I
|
W
|
C
|
130 |
TM4 | |||||||||
Q
|
N
|
H
|
R
|
S
|
V
|
R
|
T
|
A
|
F
|
140 |
A
|
V
|
C
|
G
|
C
|
V
|
W
|
V
|
V
|
T
|
150 |
F
|
V
|
M
|
C
|
I
|
P
|
V
|
F
|
V
|
Y
|
160 |
ECL2 | |||||||||
R
|
D
|
L
|
L
|
V
|
V
|
D
|
D
|
Y
|
S
|
170 |
V
|
C
|
G
|
Y
|
N
|
F
|
D
|
S
|
S
|
R
|
180 |
A
|
Y
|
D
|
Y
|
W
|
D
|
Y
|
M
|
Y
|
N
|
190 |
S
|
H
|
L
|
P
|
E
|
I
|
N
|
P
|
P
|
D
|
200 |
N
|
S
|
T
|
G
|
H
|
V
|
D
|
D
|
R
|
T
|
210 |
A
|
P
|
S
|
S
|
S
|
V
|
P
|
A
|
R
|
D
|
220 |
L
|
W
|
T
|
A
|
T
|
T
|
A
|
L
|
Q
|
S
|
230 |
Q
|
T
|
F
|
H
|
T
|
S
|
P
|
E
|
D
|
P
|
240 |
F
|
S
|
Q
|
D
|
S
|
A
|
S
|
Q
|
Q
|
P
|
250 |
H
|
Y
|
G
|
G
|
K
|
P
|
P
|
T
|
V
|
L
|
260 |
I
|
A
|
T
|
I
|
P
|
G
|
G
|
F
|
P
|
V
|
270 |
E
|
D
|
H
|
K
|
S
|
N
|
T
|
L
|
N
|
T
|
280 |
G
|
A
|
F
|
L
|
S
|
A
|
H
|
T
|
E
|
P
|
290 |
S
|
L
|
T
|
A
|
S
|
S
|
S
|
P
|
L
|
Y
|
300 |
A
|
H
|
D
|
F
|
P
|
D
|
D
|
Y
|
F
|
D
|
310 |
TM5 | |||||||||
Q
|
L
|
M
|
Y
|
G
|
N
|
H
|
A
|
W
|
T
|
320 |
P
|
Q
|
V
|
A
|
I
|
T
|
I
|
S
|
R
|
L
|
330 |
V
|
V
|
G
|
F
|
L
|
V
|
P
|
F
|
F
|
I
|
340 |
M
|
I
|
T
|
C
|
Y
|
S
|
L
|
I
|
V
|
F
|
350 |
ICL3 | |||||||||
R
|
M
|
R
|
K
|
T
|
N
|
L
|
T
|
K
|
S
|
360 |
TM6 | |||||||||
R
|
N
|
K
|
T
|
L
|
R
|
V
|
A
|
V
|
A
|
370 |
V
|
V
|
T
|
V
|
F
|
F
|
V
|
C
|
W
|
I
|
380 |
P
|
Y
|
H
|
I
|
V
|
G
|
I
|
L
|
L
|
V
|
390 |
ECL3 | TM7 | ||||||||
I
|
T
|
D
|
Q
|
E
|
S
|
A
|
L
|
R
|
E
|
400 |
V
|
V
|
L
|
P
|
W
|
D
|
H
|
M
|
S
|
I
|
410 |
A
|
L
|
A
|
S
|
A
|
N
|
S
|
C
|
F
|
N
|
420 |
H8 | |||||||||
P
|
F
|
L
|
Y
|
A
|
L
|
L
|
G
|
K
|
D
|
430 |
F
|
R
|
K
|
K
|
A
|
R
|
Q
|
S
|
V
|
K
|
440 |
C-term | |||||||||
G
|
I
|
L
|
E
|
A
|
A
|
F
|
S
|
E
|
E
|
450 |
L
|
T
|
H
|
S
|
T
|
S
|
C
|
T
|
Q
|
D
|
460 |
K
|
A
|
P
|
S
|
K
|
R
|
N
|
H
|
M
|
S
|
470 |
T
|
D
|
V
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
ENDOGENOUS LIGANDS
No endogenous ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available