CXCR5 (cxcr5_mouse)
FAMILY
Class A (Rhodopsin) Protein receptors Chemokine receptors CXCR5
GENE
Cxcr5 (Blr1, Gpcr6)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
C-X-C chemokine receptor type 5, CXC-R5, CXCR-5, Burkitt lymphoma receptor 1 homolog, CD185
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
N
|
Y
|
P
|
L
|
T
|
L
|
D
|
M
|
G
|
10 |
S
|
I
|
T
|
Y
|
N
|
M
|
D
|
D
|
L
|
Y
|
20 |
K
|
E
|
L
|
A
|
F
|
Y
|
S
|
N
|
S
|
T
|
30 |
E
|
I
|
P
|
L
|
Q
|
D
|
S
|
N
|
F
|
C
|
40 |
S
|
T
|
V
|
E
|
G
|
P
|
L
|
L
|
T
|
S
|
50 |
TM1 | |||||||||
F
|
K
|
A
|
V
|
F
|
M
|
P
|
V
|
A
|
Y
|
60 |
S
|
L
|
I
|
F
|
L
|
L
|
G
|
M
|
M
|
G
|
70 |
N
|
I
|
L
|
V
|
L
|
V
|
I
|
L
|
E
|
R
|
80 |
ICL1 | TM2 | ||||||||
H
|
R
|
H
|
T
|
R
|
S
|
S
|
T
|
E
|
T
|
90 |
F
|
L
|
F
|
H
|
L
|
A
|
V
|
A
|
D
|
L
|
100 |
L
|
L
|
V
|
F
|
I
|
L
|
P
|
F
|
A
|
V
|
110 |
ECL1 | |||||||||
A
|
E
|
G
|
S
|
V
|
G
|
W
|
V
|
L
|
G
|
120 |
TM3 | |||||||||
T
|
F
|
L
|
C
|
K
|
T
|
V
|
I
|
A
|
L
|
130 |
H
|
K
|
I
|
N
|
F
|
Y
|
C
|
S
|
S
|
L
|
140 |
L
|
L
|
A
|
C
|
I
|
A
|
V
|
D
|
R
|
Y
|
150 |
ICL2 | |||||||||
L
|
A
|
I
|
V
|
H
|
A
|
V
|
H
|
A
|
Y
|
160 |
TM4 | |||||||||
R
|
R
|
R
|
R
|
L
|
L
|
S
|
I
|
H
|
I
|
170 |
T
|
C
|
T
|
A
|
I
|
W
|
L
|
A
|
G
|
F
|
180 |
L
|
F
|
A
|
L
|
P
|
E
|
L
|
L
|
F
|
A
|
190 |
ECL2 | |||||||||
K
|
V
|
G
|
Q
|
P
|
H
|
N
|
N
|
D
|
S
|
200 |
L
|
P
|
Q
|
C
|
T
|
F
|
S
|
Q
|
E
|
N
|
210 |
TM5 | |||||||||
E
|
A
|
E
|
T
|
R
|
A
|
W
|
F
|
T
|
S
|
220 |
R
|
F
|
L
|
Y
|
H
|
I
|
G
|
G
|
F
|
L
|
230 |
L
|
P
|
M
|
L
|
V
|
M
|
G
|
W
|
C
|
Y
|
240 |
V
|
G
|
V
|
V
|
H
|
R
|
L
|
L
|
Q
|
A
|
250 |
ICL3 | TM6 | ||||||||
Q
|
R
|
R
|
P
|
Q
|
R
|
Q
|
K
|
A
|
V
|
260 |
R
|
V
|
A
|
I
|
L
|
V
|
T
|
S
|
I
|
F
|
270 |
F
|
L
|
C
|
W
|
S
|
P
|
Y
|
H
|
I
|
V
|
280 |
I
|
F
|
L
|
D
|
T
|
L
|
E
|
R
|
L
|
K
|
290 |
ECL3 | TM7 | ||||||||
A
|
V
|
N
|
S
|
S
|
C
|
E
|
L
|
S
|
G
|
300 |
Y
|
L
|
S
|
V
|
A
|
I
|
T
|
L
|
C
|
E
|
310 |
F
|
L
|
G
|
L
|
A
|
H
|
C
|
C
|
L
|
N
|
320 |
H8 | |||||||||
P
|
M
|
L
|
Y
|
T
|
F
|
A
|
G
|
V
|
K
|
330 |
F
|
R
|
S
|
D
|
L
|
S
|
R
|
L
|
L
|
T
|
340 |
C-term | |||||||||
K
|
L
|
G
|
C
|
A
|
G
|
P
|
A
|
S
|
L
|
350 |
C
|
Q
|
L
|
F
|
P
|
N
|
W
|
R
|
K
|
S
|
360 |
S
|
L
|
S
|
E
|
S
|
E
|
N
|
A
|
T
|
S
|
370 |
L
|
T
|
T
|
F
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available