GPR179 (gp179_human)
FAMILY
Class C (Glutamate) Orphan receptors Class C Orphans GPR179
GENE
GPR179 (GPR158L, GPR158L1)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Probable G-protein coupled receptor 179, Probable G-protein coupled receptor 158-like 1, GPR158-like
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
G
|
T
|
R
|
G
|
A
|
V
|
M
|
P
|
P
|
10 |
P
|
M
|
W
|
G
|
L
|
L
|
G
|
C
|
C
|
F
|
20 |
V
|
C
|
A
|
W
|
A
|
L
|
G
|
G
|
P
|
R
|
30 |
P
|
I
|
R
|
S
|
L
|
P
|
P
|
L
|
S
|
S
|
40 |
Q
|
V
|
K
|
P
|
G
|
S
|
V
|
P
|
M
|
Q
|
50 |
V
|
P
|
L
|
E
|
G
|
A
|
E
|
A
|
A
|
L
|
60 |
A
|
Y
|
L
|
Y
|
S
|
G
|
D
|
A
|
Q
|
Q
|
70 |
L
|
S
|
Q
|
V
|
N
|
C
|
S
|
E
|
R
|
Y
|
80 |
E
|
A
|
R
|
G
|
A
|
G
|
A
|
M
|
P
|
G
|
90 |
L
|
P
|
P
|
S
|
L
|
Q
|
G
|
A
|
A
|
G
|
100 |
T
|
L
|
A
|
Q
|
A
|
A
|
N
|
F
|
L
|
N
|
110 |
M
|
L
|
L
|
Q
|
A
|
N
|
D
|
I
|
R
|
E
|
120 |
S
|
S
|
V
|
E
|
E
|
D
|
V
|
E
|
W
|
Y
|
130 |
Q
|
A
|
L
|
V
|
R
|
S
|
V
|
A
|
E
|
G
|
140 |
D
|
P
|
R
|
V
|
Y
|
R
|
A
|
L
|
L
|
T
|
150 |
F
|
N
|
P
|
P
|
P
|
G
|
A
|
S
|
H
|
L
|
160 |
Q
|
L
|
A
|
L
|
Q
|
A
|
T
|
R
|
T
|
G
|
170 |
E
|
E
|
T
|
I
|
L
|
Q
|
D
|
L
|
S
|
G
|
180 |
N
|
W
|
V
|
Q
|
E
|
E
|
N
|
P
|
P
|
G
|
190 |
D
|
L
|
D
|
T
|
P
|
A
|
L
|
K
|
K
|
R
|
200 |
V
|
L
|
T
|
N
|
D
|
L
|
G
|
S
|
L
|
G
|
210 |
S
|
P
|
K
|
W
|
P
|
Q
|
A
|
D
|
G
|
Y
|
220 |
V
|
G
|
D
|
T
|
Q
|
Q
|
V
|
R
|
L
|
S
|
230 |
P
|
P
|
F
|
L
|
E
|
C
|
Q
|
E
|
G
|
R
|
240 |
L
|
R
|
P
|
G
|
W
|
L
|
I
|
T
|
L
|
S
|
250 |
A
|
T
|
F
|
Y
|
G
|
L
|
K
|
P
|
D
|
L
|
260 |
S
|
P
|
E
|
V
|
R
|
G
|
Q
|
V
|
Q
|
M
|
270 |
D
|
V
|
D
|
L
|
Q
|
S
|
V
|
D
|
I
|
N
|
280 |
Q
|
C
|
A
|
S
|
G
|
P
|
G
|
W
|
Y
|
S
|
290 |
N
|
T
|
H
|
L
|
C
|
D
|
L
|
N
|
S
|
T
|
300 |
Q
|
C
|
V
|
P
|
L
|
E
|
S
|
Q
|
G
|
F
|
310 |
V
|
L
|
G
|
R
|
Y
|
L
|
C
|
R
|
C
|
R
|
320 |
P
|
G
|
F
|
Y
|
G
|
A
|
S
|
P
|
S
|
G
|
330 |
G
|
L
|
E
|
E
|
S
|
D
|
F
|
Q
|
T
|
T
|
340 |
G
|
Q
|
F
|
G
|
F
|
P
|
E
|
G
|
R
|
S
|
350 |
G
|
R
|
L
|
L
|
Q
|
C
|
L
|
P
|
C
|
P
|
360 |
E
|
G
|
C
|
T
|
S
|
C
|
M
|
D
|
A
|
T
|
370 |
TM1 | |||||||||
P
|
C
|
L
|
V
|
E
|
E
|
A
|
A
|
V
|
L
|
380 |
R
|
A
|
A
|
V
|
L
|
A
|
C
|
Q
|
A
|
C
|
390 |
C
|
M
|
L
|
A
|
I
|
F
|
L
|
S
|
M
|
L
|
400 |
ICL1 | |||||||||
V
|
S
|
Y
|
R
|
C
|
R
|
R
|
N
|
K
|
R
|
410 |
TM2 | |||||||||
I
|
W
|
A
|
S
|
G
|
V
|
V
|
L
|
L
|
E
|
420 |
T
|
V
|
L
|
F
|
G
|
F
|
L
|
L
|
L
|
Y
|
430 |
F
|
P
|
V
|
F
|
I
|
L
|
Y
|
F
|
K
|
P
|
440 |
ECL1 | TM3 | ||||||||
S
|
V
|
F
|
R
|
C
|
I
|
A
|
L
|
R
|
W
|
450 |
V
|
R
|
L
|
L
|
G
|
F
|
A
|
I
|
V
|
Y
|
460 |
G
|
T
|
I
|
I
|
L
|
K
|
L
|
Y
|
R
|
V
|
470 |
L
|
Q
|
L
|
F
|
L
|
S
|
R
|
T
|
A
|
Q
|
480 |
ICL2 | TM4 | ||||||||
R
|
S
|
A
|
L
|
L
|
S
|
S
|
G
|
R
|
L
|
490 |
L
|
R
|
R
|
L
|
G
|
L
|
L
|
L
|
L
|
P
|
500 |
V
|
L
|
G
|
F
|
L
|
A
|
V
|
W
|
T
|
V
|
510 |
ECL2 | |||||||||
G
|
A
|
L
|
E
|
R
|
G
|
I
|
Q
|
H
|
A
|
520 |
P
|
L
|
V
|
I
|
R
|
G
|
H
|
T
|
P
|
S
|
530 |
G
|
R
|
H
|
F
|
Y
|
L
|
C
|
H
|
H
|
D
|
540 |
TM5 | |||||||||
R
|
W
|
D
|
Y
|
I
|
M
|
V
|
V
|
A
|
E
|
550 |
L
|
L
|
L
|
L
|
C
|
W
|
G
|
S
|
F
|
L
|
560 |
ICL3 | |||||||||
C
|
Y
|
A
|
T
|
R
|
A
|
V
|
L
|
S
|
A
|
570 |
TM6 | |||||||||
F
|
H
|
E
|
P
|
R
|
Y
|
M
|
G
|
I
|
A
|
580 |
L
|
H
|
N
|
E
|
L
|
L
|
L
|
S
|
A
|
A
|
590 |
F
|
H
|
T
|
A
|
R
|
F
|
V
|
L
|
V
|
P
|
600 |
ECL3 | TM7 | ||||||||
S
|
L
|
H
|
P
|
D
|
W
|
T
|
L
|
L
|
L
|
610 |
F
|
F
|
F
|
H
|
T
|
H
|
S
|
T
|
V
|
T
|
620 |
T
|
T
|
L
|
A
|
L
|
I
|
F
|
I
|
P
|
K
|
630 |
H8 | |||||||||
F
|
W
|
K
|
L
|
G
|
A
|
P
|
P
|
R
|
E
|
640 |
E
|
M
|
V
|
D
|
E
|
V
|
C
|
E
|
D
|
E
|
650 |
C-term | |||||||||
L
|
D
|
L
|
Q
|
H
|
S
|
G
|
S
|
Y
|
L
|
660 |
G
|
S
|
S
|
I
|
A
|
S
|
A
|
W
|
S
|
E
|
670 |
H
|
S
|
L
|
D
|
P
|
G
|
D
|
I
|
R
|
D
|
680 |
E
|
L
|
K
|
K
|
L
|
Y
|
A
|
Q
|
L
|
E
|
690 |
V
|
H
|
K
|
T
|
K
|
E
|
M
|
A
|
A
|
N
|
700 |
N
|
P
|
H
|
L
|
P
|
K
|
K
|
R
|
G
|
S
|
710 |
S
|
C
|
Q
|
G
|
L
|
G
|
R
|
S
|
F
|
M
|
720 |
R
|
Y
|
L
|
A
|
E
|
F
|
P
|
E
|
A
|
L
|
730 |
A
|
R
|
Q
|
H
|
S
|
R
|
D
|
S
|
G
|
S
|
740 |
P
|
G
|
H
|
G
|
S
|
L
|
P
|
G
|
S
|
S
|
750 |
R
|
R
|
R
|
L
|
L
|
S
|
S
|
S
|
L
|
Q
|
760 |
E
|
P
|
E
|
G
|
T
|
P
|
A
|
L
|
H
|
K
|
770 |
S
|
R
|
S
|
T
|
Y
|
D
|
Q
|
R
|
R
|
E
|
780 |
Q
|
D
|
P
|
P
|
L
|
L
|
D
|
S
|
L
|
L
|
790 |
R
|
R
|
K
|
L
|
A
|
K
|
K
|
A
|
S
|
R
|
800 |
T
|
E
|
S
|
R
|
E
|
S
|
V
|
E
|
G
|
P
|
810 |
P
|
A
|
L
|
G
|
F
|
R
|
S
|
A
|
S
|
A
|
820 |
H
|
N
|
L
|
T
|
V
|
G
|
E
|
R
|
L
|
P
|
830 |
R
|
A
|
R
|
P
|
A
|
S
|
L
|
Q
|
K
|
S
|
840 |
L
|
S
|
V
|
A
|
S
|
S
|
R
|
E
|
K
|
A
|
850 |
L
|
L
|
M
|
A
|
S
|
Q
|
A
|
Y
|
L
|
E
|
860 |
E
|
T
|
Y
|
R
|
Q
|
A
|
K
|
E
|
R
|
E
|
870 |
E
|
R
|
K
|
K
|
A
|
K
|
A
|
A
|
M
|
A
|
880 |
S
|
L
|
V
|
R
|
R
|
P
|
S
|
A
|
R
|
R
|
890 |
L
|
E
|
R
|
P
|
R
|
G
|
A
|
P
|
L
|
S
|
900 |
A
|
P
|
P
|
S
|
P
|
A
|
K
|
S
|
S
|
S
|
910 |
V
|
D
|
S
|
S
|
H
|
T
|
S
|
G
|
R
|
L
|
920 |
H
|
E
|
E
|
A
|
R
|
R
|
R
|
L
|
P
|
H
|
930 |
P
|
P
|
I
|
R
|
H
|
Q
|
V
|
S
|
T
|
P
|
940 |
I
|
L
|
A
|
L
|
S
|
G
|
G
|
L
|
G
|
E
|
950 |
P
|
R
|
M
|
L
|
S
|
P
|
T
|
S
|
T
|
L
|
960 |
A
|
P
|
A
|
L
|
L
|
P
|
A
|
L
|
A
|
P
|
970 |
T
|
P
|
A
|
P
|
A
|
L
|
A
|
P
|
V
|
P
|
980 |
V
|
S
|
P
|
Q
|
S
|
P
|
N
|
L
|
L
|
T
|
990 |
Y
|
I
|
C
|
P
|
W
|
E
|
N
|
A
|
E
|
L
|
1000 |
P
|
A
|
K
|
Q
|
E
|
N
|
V
|
P
|
Q
|
E
|
1010 |
G
|
P
|
S
|
G
|
P
|
E
|
R
|
G
|
H
|
H
|
1020 |