Y2 receptor (q9erc0_rat)
FAMILY
Class A (Rhodopsin) Peptide receptors Neuropeptide Y receptors Y2 receptor
GENE
Npy2r (rCG_62488)
ORGANISM
Rat (Rattus norvegicus)
ALT. NAMES
Neuropeptide Y receptor type 2, NPY-Y2 receptor
SOURCE
TREMBL
SEQUENCE
N-term | |||||||||
M
|
G
|
P
|
L
|
G
|
A
|
E
|
A
|
D
|
E
|
10 |
N
|
Q
|
T
|
V
|
E
|
V
|
K
|
V
|
E
|
L
|
20 |
Y
|
G
|
S
|
G
|
P
|
T
|
T
|
P
|
R
|
G
|
30 |
E
|
L
|
P
|
P
|
D
|
P
|
E
|
P
|
E
|
L
|
40 |
TM1 | |||||||||
I
|
D
|
S
|
T
|
K
|
L
|
V
|
E
|
V
|
Q
|
50 |
V
|
V
|
L
|
I
|
L
|
A
|
Y
|
C
|
S
|
I
|
60 |
I
|
L
|
L
|
G
|
V
|
V
|
G
|
N
|
S
|
L
|
70 |
V
|
I
|
H
|
V
|
V
|
I
|
K
|
F
|
K
|
S
|
80 |
ICL1 | TM2 | ||||||||
M
|
R
|
T
|
V
|
T
|
N
|
F
|
F
|
I
|
A
|
90 |
N
|
L
|
A
|
V
|
A
|
D
|
L
|
L
|
V
|
N
|
100 |
T
|
L
|
C
|
L
|
P
|
F
|
T
|
L
|
T
|
Y
|
110 |
ECL1 | |||||||||
T
|
L
|
M
|
G
|
E
|
W
|
K
|
M
|
G
|
P
|
120 |
TM3 | |||||||||
V
|
L
|
C
|
H
|
L
|
V
|
P
|
Y
|
A
|
Q
|
130 |
G
|
L
|
A
|
V
|
Q
|
V
|
S
|
T
|
I
|
T
|
140 |
L
|
T
|
V
|
I
|
A
|
L
|
D
|
R
|
H
|
R
|
150 |
ICL2 | |||||||||
C
|
I
|
V
|
Y
|
H
|
L
|
E
|
S
|
K
|
I
|
160 |
TM4 | |||||||||
S
|
K
|
Q
|
I
|
S
|
F
|
L
|
I
|
I
|
G
|
170 |
L
|
A
|
W
|
G
|
V
|
S
|
A
|
L
|
L
|
A
|
180 |
S
|
P
|
L
|
A
|
I
|
F
|
R
|
E
|
Y
|
S
|
190 |
ECL2 | |||||||||
L
|
I
|
E
|
I
|
I
|
P
|
D
|
F
|
E
|
I
|
200 |
V
|
A
|
C
|
T
|
E
|
K
|
W
|
P
|
G
|
E
|
210 |
TM5 | |||||||||
E
|
K
|
S
|
V
|
Y
|
G
|
T
|
V
|
Y
|
S
|
220 |
L
|
S
|
T
|
L
|
L
|
I
|
L
|
Y
|
V
|
L
|
230 |
P
|
L
|
G
|
I
|
I
|
S
|
F
|
S
|
Y
|
T
|
240 |
R
|
I
|
W
|
S
|
K
|
L
|
K
|
N
|
H
|
V
|
250 |
ICL3 | TM6 | ||||||||
S
|
P
|
G
|
A
|
A
|
S
|
D
|
H
|
Y
|
H
|
260 |
Q
|
R
|
R
|
H
|
K
|
T
|
T
|
K
|
M
|
L
|
270 |
V
|
C
|
V
|
V
|
V
|
V
|
F
|
A
|
V
|
S
|
280 |
W
|
L
|
P
|
L
|
H
|
A
|
F
|
Q
|
L
|
A
|
290 |
ECL3 | |||||||||
V
|
D
|
I
|
D
|
S
|
H
|
V
|
L
|
D
|
L
|
300 |
TM7 | |||||||||
K
|
E
|
Y
|
K
|
L
|
I
|
F
|
T
|
V
|
F
|
310 |
H
|
I
|
I
|
A
|
M
|
C
|
S
|
T
|
F
|
A
|
320 |
H8 | |||||||||
N
|
P
|
L
|
L
|
Y
|
G
|
W
|
M
|
N
|
S
|
330 |
N
|
Y
|
R
|
K
|
A
|
F
|
L
|
S
|
A
|
F
|
340 |
R
|
C
|
E
|
Q
|
R
|
L
|
D
|
A
|
I
|
H
|
350 |
C-term | |||||||||
S
|
E
|
V
|
S
|
M
|
T
|
F
|
K
|
A
|
K
|
360 |
K
|
N
|
L
|
E
|
V
|
K
|
K
|
N
|
N
|
G
|
370 |
L
|
T
|
D
|
S
|
F
|
S
|
E
|
A
|
T
|
N
|
380 |
V
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
ENDOGENOUS LIGANDS
neuropeptide Y, peptide YY
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available