SST2 receptor (ssr2_rat)
FAMILY
Class A (Rhodopsin) Peptide receptors Somatostatin receptors SST2 receptor
GENE
Sstr2
ORGANISM
Rat (Rattus norvegicus)
ALT. NAMES
Somatostatin receptor type 2, SS-2-R, SS2-R, SS2R, SRIF-1
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
E
|
L
|
T
|
S
|
E
|
Q
|
F
|
N
|
G
|
10 |
S
|
Q
|
V
|
W
|
I
|
P
|
S
|
P
|
F
|
D
|
20 |
L
|
N
|
G
|
S
|
L
|
G
|
P
|
S
|
N
|
G
|
30 |
S
|
N
|
Q
|
T
|
E
|
P
|
Y
|
Y
|
D
|
M
|
40 |
TM1 | |||||||||
T
|
S
|
N
|
A
|
V
|
L
|
T
|
F
|
I
|
Y
|
50 |
F
|
V
|
V
|
C
|
V
|
V
|
G
|
L
|
C
|
G
|
60 |
N
|
T
|
L
|
V
|
I
|
Y
|
V
|
I
|
L
|
R
|
70 |
ICL1 | TM2 | ||||||||
Y
|
A
|
K
|
M
|
K
|
T
|
I
|
T
|
N
|
I
|
80 |
Y
|
I
|
L
|
N
|
L
|
A
|
I
|
A
|
D
|
E
|
90 |
L
|
F
|
M
|
L
|
G
|
L
|
P
|
F
|
L
|
A
|
100 |
ECL1 | |||||||||
M
|
Q
|
V
|
A
|
L
|
V
|
H
|
W
|
P
|
F
|
110 |
TM3 | |||||||||
G
|
K
|
A
|
I
|
C
|
R
|
V
|
V
|
M
|
T
|
120 |
V
|
D
|
G
|
I
|
N
|
Q
|
F
|
T
|
S
|
I
|
130 |
F
|
C
|
L
|
T
|
V
|
M
|
S
|
I
|
D
|
R
|
140 |
ICL2 | |||||||||
Y
|
L
|
A
|
V
|
V
|
H
|
P
|
I
|
K
|
S
|
150 |
TM4 | |||||||||
A
|
K
|
W
|
R
|
R
|
P
|
R
|
T
|
A
|
K
|
160 |
M
|
I
|
N
|
V
|
A
|
V
|
W
|
G
|
V
|
S
|
170 |
L
|
L
|
V
|
I
|
L
|
P
|
I
|
M
|
I
|
Y
|
180 |
ECL2 | |||||||||
A
|
G
|
L
|
R
|
S
|
N
|
Q
|
W
|
G
|
R
|
190 |
S
|
S
|
C
|
T
|
I
|
N
|
W
|
P
|
G
|
E
|
200 |
TM5 | |||||||||
S
|
G
|
A
|
W
|
Y
|
T
|
G
|
F
|
I
|
I
|
210 |
Y
|
A
|
F
|
I
|
L
|
G
|
F
|
L
|
V
|
P
|
220 |
L
|
T
|
I
|
I
|
C
|
L
|
C
|
Y
|
L
|
F
|
230 |
I
|
I
|
I
|
K
|
V
|
K
|
S
|
S
|
G
|
I
|
240 |
ICL3 | TM6 | ||||||||
R
|
V
|
G
|
S
|
S
|
K
|
R
|
K
|
K
|
S
|
250 |
E
|
K
|
K
|
V
|
T
|
R
|
M
|
V
|
S
|
I
|
260 |
V
|
V
|
A
|
V
|
F
|
I
|
F
|
C
|
W
|
L
|
270 |
P
|
F
|
Y
|
I
|
F
|
N
|
V
|
S
|
S
|
V
|
280 |
ECL3 | TM7 | ||||||||
S
|
V
|
A
|
I
|
S
|
P
|
T
|
P
|
A
|
L
|
290 |
K
|
G
|
M
|
F
|
D
|
F
|
V
|
V
|
I
|
L
|
300 |
T
|
Y
|
A
|
N
|
S
|
C
|
A
|
N
|
P
|
I
|
310 |
H8 | |||||||||
L
|
Y
|
A
|
F
|
L
|
S
|
D
|
N
|
F
|
K
|
320 |
K
|
S
|
F
|
Q
|
N
|
V
|
L
|
C
|
L
|
V
|
330 |
C-term | |||||||||
K
|
V
|
S
|
G
|
A
|
E
|
D
|
G
|
E
|
R
|
340 |
S
|
D
|
S
|
K
|
Q
|
D
|
K
|
S
|
R
|
L
|
350 |
N
|
E
|
T
|
T
|
E
|
T
|
Q
|
R
|
T
|
L
|
360 |
L
|
N
|
G
|
D
|
L
|
Q
|
T
|
S
|
I
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
ENDOGENOUS LIGANDS
SRIF-28, SRIF-14
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available