TAS2R13 (tr140_mouse)

FAMILY

Taste 2 Sensory receptors Taste 2 receptors TAS2R13

GENE

Tas2r140 (T2r64, Tas2r13, Tas2r137, Tas2r40, Tas2r8)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

Taste receptor type 2 member 140, T2R140, T2R13, T2R8, Taste receptor family B member 3, mTRB3, mTRB5, Taste receptor type 2 member 40, T2R40, mT2r64

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
N
A
T
V
K
C
T
L
L
10
                   
I
I
L
G
V
E
I
I
I
G
20
                   
C
L
G
N
G
F
I
A
V
V
30
            ICL1
N
I
M
D
W
A
K
R
R
K
40
TM2              
I
S
L
V
D
Q
I
F
T
A
50
                   
L
A
I
S
R
L
A
F
V
W
60
                   
S
L
L
T
V
L
F
T
S
E
70
    ECL1   TM3
L
Y
S
A
L
M
T
T
R
K
80
                   
V
L
I
I
F
N
N
S
W
T
90
                   
V
I
N
H
F
N
I
W
L
A
100
                   
T
C
L
S
I
F
Y
F
L
M
110
      ICL2      
I
A
N
F
S
N
S
I
F
L
120
      TM4        
S
L
R
W
R
V
K
T
V
V
130
                   
S
V
T
L
L
M
S
L
L
L
140
                   
L
F
V
N
V
L
V
I
N
T
150
ECL2            
F
I
V
I
S
V
D
V
Y
K
160
                   
V
N
T
S
Y
S
S
H
S
D
170
  TM5            
N
N
I
H
I
S
R
I
F
L
180
                   
F
T
N
T
I
F
T
F
I
P
190
                   
F
S
V
T
L
T
I
F
L
L
200
                   
L
I
F
S
L
W
T
H
L
K
210
    ICL3        
N
M
Q
H
N
A
K
D
S
R
220
  TM6            
D
P
S
T
T
A
H
I
K
A
230
                   
L
Q
M
M
V
T
F
L
L
L
240
                   
Y
T
I
F
F
L
A
L
V
M
250
        ECL3    
Q
S
S
K
M
K
F
L
S
S
260
TM7              
T
V
F
N
Y
F
F
E
V
I
270
                   
S
L
A
F
P
S
G
H
S
C
280
          H8      
V
L
I
L
G
N
S
K
L
R
290
                   
Q
T
F
I
S
T
V
W
W
L
300
C-term        
K
S
S
F
N
A
A
E
L
P
310
   
G
P

LINKS

DIAGRAMS

G N G L C G I I I E V G L I I L L T C K 1 T A L A I S R L A F V W S L L T V L F T 2 C T A L W I N F H N I V T W S N N F I I 3 T V V S V T L L M S L L L L F V N V L V 4 F I T L T V S F P I F T F I T N T F L F 5 L Q M M V T F L L L Y T I F F L A L V M 6 C S H G S P F A L S I V E F F Y N F V T 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

K R R K ICL1ECL1 S A L M T ECL1 N F S S I F L S L R ICL2ECL2 F I V I S V D V Y K V N T S Y S S H S D N ECL2ICL3 Q H N A K D S R D ICL3ECL3 M K F L S ECL3N-term M N A T V N-termC-term L K S S F N A A E L P G P C-term K C T L L I I L G V E I I I G C L G N G F I A V V N I M D W A I S L V D Q I F T A L A I S R L A F V W S L L T V L F T S E L Y T R K V L I I F N N S W T V I N H F N I W L A T C L S I F Y F L M I A N W R V K T V V S V T L L M S L L L L F V N V L V I N T N I H I S R I F L F T N T I F T F I P F S V T L T I F L L L I F S L W T H L K N M P S T T A H I K A L Q M M V T F L L L Y T I F F L A L V M Q S S K S T V F N Y F F E V I S L A F P S G H S C V L I L G N S K F I S L R Q T T V W W
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

STRUCTURES

No structures available