CCR5

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

CCR5

PDB CODE

6AKX

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

B

REFERENCE

10.1021/ACS.JMEDCHEM.8B01077

PUBLICATION DATE

Oct. 24, 2018

RECEPTOR PDB

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INTERACTING RESIDUES

28 interactions (Click to see)

REFINED STRUCTURE MODEL

6AKX_refined

LIGANDS

N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl}-1-(thiophen-2-yl)propyl]cyclopentanecarboxamide - Antagonist

ENDOGENOUS LIGANDS

CCL16,

CCL14,

CCL3,

CCL5,

CCL7,

CCL13,

CCL8,

CCL4,

CCL2,

CCL11