G13 - Olfactory receptor 51G1 complex model

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

G12/13

DATE

2023-09-15

3D VIEW

NGL is a WebGL based 3D viewer powered by MMTF.


Tertiary structure confidence

(pLDDT score) avg.: 79.5

Very high (>90)
Confident (90-70)
Low (70-50)
Very low (<50)
Disordered

PTM Score: 0.5
iPTM Score: 0.2
PAE mean: 25.9


GPCR - G protein interface interactions



The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.


Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):





Structures

Sequence Color

, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Interaction
type
GPCR
Segment

AA

Number
Generic
number

segment

AA

Number
Generic
number
Hydrophobic H8 T 298 8x47 G.H5 Q 377 G.H5.26
Van-der-waals H8 T 298 8x47 G.H5 Q 377 G.H5.26
Hydrophobic TM6 Q 234 6x28 G.h4s6 Q 339 G.h4s6.13
Van-der-waals TM6 Q 234 6x28 G.h4s6 Q 339 G.h4s6.13
Polar ICL1 A 55 12x48 G.HN K 42 G.HN.51
Hydrophobic ICL1 A 55 12x48 G.HN K 42 G.HN.51
Van-der-waals ICL1 A 55 12x48 G.HN K 42 G.HN.51
Hydrophobic TM3 V 128 3x54 G.H5 M 375 G.H5.24
Van-der-waals TM3 V 128 3x54 G.H5 M 375 G.H5.24
Polar H8 Q 300 8x49 G.H5 Q 377 G.H5.26
Hydrophobic H8 Q 300 8x49 G.H5 Q 377 G.H5.26
Van-der-waals H8 Q 300 8x49 G.H5 Q 377 G.H5.26
Polar TM6 R 238 6x32 G.h4s6 Q 339 G.h4s6.13
Van-der-waals TM6 R 238 6x32 G.h4s6 Q 339 G.h4s6.13
Hydrophobic ICL2 T 136 34x55 G.s2s3 N 215 G.s2s3.02
Van-der-waals ICL2 T 136 34x55 G.s2s3 N 215 G.s2s3.02
Hydrophobic TM2 Y 63 2x41 G.HN T 43 G.HN.52
Hydrophobic TM6 R 238 6x32 G.H5 L 376 G.H5.25
Hydrophobic TM4 T 139 4x38 G.hns1 R 47 G.hns1.03
Van-der-waals TM4 T 139 4x38 G.hns1 R 47 G.hns1.03
Polar TM3 R 124 3x50 G.H5 M 375 G.H5.24
Hydrophobic TM3 R 124 3x50 G.H5 M 375 G.H5.24
Van-der-waals TM3 R 124 3x50 G.H5 M 375 G.H5.24
Hydrophobic ICL2 P 131 34x50 G.H5 H 368 G.H5.17
Hydrophobic ICL1 T 56 12x49 G.HN K 42 G.HN.51
Polar TM6 T 242 6x36 G.H5 M 375 G.H5.24
Hydrophobic TM6 T 242 6x36 G.H5 M 375 G.H5.24
Van-der-waals TM6 T 242 6x36 G.H5 M 375 G.H5.24
Hydrophobic ICL2 L 132 34x51 G.S3 F 218 G.S3.03
Ionic TM6 E 235 6x29 G.H5 K 372 G.H5.21
Polar TM6 E 235 6x29 G.H5 K 372 G.H5.21
Hydrophobic TM6 E 235 6x29 G.H5 K 372 G.H5.21
Van-der-waals TM6 E 235 6x29 G.H5 K 372 G.H5.21
Hydrophobic TM2 P 60 2x38 G.hns1 R 47 G.hns1.03
Van-der-waals TM2 P 60 2x38 G.hns1 R 47 G.hns1.03
Hydrophobic TM6 R 238 6x32 G.H5 K 372 G.H5.21
Hydrophobic ICL2 L 132 34x51 G.S3 V 216 G.S3.01
Van-der-waals ICL2 L 132 34x51 G.S3 V 216 G.S3.01
Hydrophobic TM3 A 127 3x53 G.H5 M 375 G.H5.24
Van-der-waals TM3 A 127 3x53 G.H5 M 375 G.H5.24
Polar ICL2 H 133 34x52 G.s2s3 K 214 G.s2s3.01
Hydrophobic ICL2 H 133 34x52 G.s2s3 K 214 G.s2s3.01
Van-der-waals ICL2 H 133 34x52 G.s2s3 K 214 G.s2s3.01
Hydrophobic ICL2 D 134 34x53 G.H5 L 371 G.H5.20
Hydrophobic ICL2 L 132 34x51 G.H5 K 363 G.H5.12
Van-der-waals ICL2 L 132 34x51 G.H5 K 363 G.H5.12
Hydrophobic TM5 I 230 5x68 G.H5 H 368 G.H5.17
Van-der-waals TM5 I 230 5x68 G.H5 H 368 G.H5.17
Hydrophobic TM3 V 128 3x54 G.H5 L 371 G.H5.20
Van-der-waals TM3 V 128 3x54 G.H5 L 371 G.H5.20
Polar TM6 T 242 6x36 G.H5 L 376 G.H5.25
Hydrophobic ICL2 P 131 34x50 G.H5 L 371 G.H5.20
Van-der-waals ICL2 P 131 34x50 G.H5 L 371 G.H5.20
Hydrophobic ICL2 T 136 34x55 G.S3 V 216 G.S3.01
Hydrophobic TM3 N 130 3x56 G.H5 L 371 G.H5.20
Van-der-waals TM2 Y 62 2x40 G.hns1 K 46 G.hns1.02
Ionic TM6 E 235 6x29 G.H5 H 368 G.H5.17
Hydrophobic TM2 G 59 2x37 G.hns1 K 46 G.hns1.02
Van-der-waals TM2 G 59 2x37 G.hns1 K 46 G.hns1.02
Hydrophobic ICL2 H 133 34x52 G.S3 V 216 G.S3.01
Van-der-waals ICL2 H 133 34x52 G.S3 V 216 G.S3.01
Polar ICL1 L 57 12x50 G.hns1 K 46 G.hns1.02
Hydrophobic ICL1 L 57 12x50 G.hns1 K 46 G.hns1.02
Van-der-waals ICL1 L 57 12x50 G.hns1 K 46 G.hns1.02
Polar ICL1 T 56 12x49 G.hns1 K 46 G.hns1.02
Hydrophobic ICL1 T 56 12x49 G.hns1 K 46 G.hns1.02
Van-der-waals ICL1 T 56 12x49 G.hns1 K 46 G.hns1.02
Polar TM2 Y 62 2x40 G.H5 Q 377 G.H5.26
Hydrophobic TM2 Y 62 2x40 G.H5 Q 377 G.H5.26
Van-der-waals TM2 Y 62 2x40 G.H5 Q 377 G.H5.26
Hydrophobic TM3 A 127 3x53 G.H5 L 371 G.H5.20
Van-der-waals TM3 A 127 3x53 G.H5 L 371 G.H5.20
Ionic ICL2 D 134 34x53 G.hns1 R 47 G.hns1.03
Polar ICL2 D 134 34x53 G.hns1 R 47 G.hns1.03
Hydrophobic ICL2 D 134 34x53 G.hns1 R 47 G.hns1.03
Van-der-waals ICL2 D 134 34x53 G.hns1 R 47 G.hns1.03
Hydrophobic TM4 P 140 4x39 G.HN T 43 G.HN.52
Hydrophobic ICL2 P 131 34x50 G.H5 L 367 G.H5.16
Van-der-waals ICL2 P 131 34x50 G.H5 L 367 G.H5.16
Polar ICL2 L 138 34x57 G.hns1 R 47 G.hns1.03
Hydrophobic ICL2 L 138 34x57 G.hns1 R 47 G.hns1.03
Van-der-waals ICL2 L 138 34x57 G.hns1 R 47 G.hns1.03
Hydrophobic ICL1 H 58 12x51 G.hns1 K 46 G.hns1.02
Van-der-waals ICL1 H 58 12x51 G.hns1 K 46 G.hns1.02
Hydrophobic TM6 A 239 6x33 G.H5 M 375 G.H5.24
Van-der-waals TM6 A 239 6x33 G.H5 M 375 G.H5.24
Hydrophobic ICL2 L 132 34x51 G.H5 L 367 G.H5.16
Van-der-waals ICL2 L 132 34x51 G.H5 L 367 G.H5.16
Polar TM6 Q 234 6x28 G.h4s6 Q 338 G.h4s6.12
Van-der-waals TM6 Q 234 6x28 G.h4s6 Q 338 G.h4s6.12
Polar ICL2 S 135 34x54 G.hns1 R 47 G.hns1.03
Hydrophobic ICL2 S 135 34x54 G.hns1 R 47 G.hns1.03
Van-der-waals ICL2 S 135 34x54 G.hns1 R 47 G.hns1.03
Polar TM6 E 235 6x29 G.S6 Y 343 G.S6.02
Van-der-waals TM6 E 235 6x29 G.S6 Y 343 G.S6.02
Hydrophobic ICL2 S 135 34x54 G.S3 P 217 G.S3.02
Van-der-waals ICL2 S 135 34x54 G.S3 P 217 G.S3.02