( Setmelanotide - MC4 receptor model)

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

LIGAND

Setmelanotide

DATE

2026-03-01

ORIGIN

Model (Boltz2)

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Tertiary structure confidence

pLDDT score avg.: 86.9

Very high (>90)
Confident (90-70)
Low (70-50)
Very low (<50)
Disordered

PTM Score: 0.9
iPTM Score: 0.9
Ligand pLDDT Score: 0.7
Vicinity pLDDT (5Å): 0.8
Ligand iPTM Score: 0.9