chlordiazepoxide


SMILES CNC1=Nc2ccc(cc2C(=[N+](C1)[O-])c1ccccc1)Cl
InChIKey ANTSCNMPPGJYLG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 299.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TRH1 TRHR Mouse Thyrotropin-releasing hormone A pKi 4.7 4.7 4.7 Guide to Pharmacology
TRH1 TRHR Rat Thyrotropin-releasing hormone A pKi 4.82 4.82 4.82 Guide to Pharmacology
H1 HRH1 Human Histamine A pKi 6.68 6.68 6.68 ChEMBL
TRH1 TRFR Human Thyrotropin-releasing hormone A pKi 8.18 8.18 8.18 Drug Central
TRH1 TRHR Mouse Thyrotropin-releasing hormone A pKi 8.33 8.33 8.33 Drug Central
TRH1 TRHR Rat Thyrotropin-releasing hormone A pKi 8.32 8.32 8.32 Drug Central
H1 HRH1 Human Histamine A pKi 8.18 8.18 8.18 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pIC50 5.75 5.75 5.75 ChEMBL