apelin-13 (Human) [903]



apelin-13 (Human)


SMILES CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O
InChIKey XXCCRHIAIBQDPX-PEWBXTNBSA-N
Sequence QRPRLSHKGPMPF
HELM PEPTIDE1{Q.R.P.R.L.S.H.K.G.P.M.P.F}$$$$

Chemical Properties

Hydrogen bond acceptors 21
Hydrogen bond donors 19
Rotatable bonds 47
Log P -6.132
Molecular weight (Da) 1549.8
Stereochemistry info unspecified

Database connections

Structure pdb 8XQE 8XQF 8XZG
Model (AF2) apelin
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

apelin-13 (Human)


Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Structure pdb 8XQE 8XQF 8XZG
Model (AF2) apelin

Compound is not listed as a drug.