Structure information

A2A receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5IU7

SPECIES

Homo sapiens

RESOLUTION

1.900

PREFERRED CHAIN

A

PUBLICATION DATE

June 29, 2016

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
6DY L85 3.33x33 TM3 hydrophobic
6DY F168 45.52x52 ECL2 aromatic (face-to-face)
6DY E169 ECL2 polar (charge-assisted hydrogen bond)
6DY M177 5.38x40 TM5 hydrophobic
6DY W246 6.48x48 TM6 hydrophobic
6DY L249 6.51x51 TM6 hydrophobic
6DY H250 6.52x52 TM6 aromatic (face-to-edge)
6DY N253 6.55x55 TM6 polar (hydrogen bond)
6DY N253 6.55x55 TM6 polar (hydrogen bond)
6DY N253 6.55x55 TM6 polar (hydrogen bond)
6DY H264 ECL3 aromatic (face-to-face)
6DY M270 7.35x34 TM7 hydrophobic

Ligands

6DY

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Residue Diagrams

V N G L I A L V A I A L E V T I Y V S S 1 V S L A A A D I A V G L V A I P F A I T I 2 A L L S F I S S Q T L V L V F C A I F L 3 A K G I I A I C W V L S F A I G L T P M 4 Y V G L M L L L P V L V C A F F N F Y V M Y 5 A I I V G L F A L C W L P L H I I N C F 6 F P N V V S N T H S L V I A L Y M L W 7
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ICL1 S N L Q ICL1ECL1 F C A ECL1ICL2 P L R Y N G L V ICL2ECL2 W N N C G Q P K E G K N H S Q G C G E G Q V A C L F E D V V ECL2ICL3 Q P L P G ICL3ECL3 P D C S H A ECL3C-term K A A G T S A R V L A A H G S D G E Q V S L R L N G H P P G V W A N G S A P H P E R R P N G Y A L G L V S G G S A Q E S Q G N T G L P D V E L L S H E L K G V C P E P P G L D D P L A Q D G A G V S C-term M P I M G S S V Y I T V E L A I A V L A I L G N V L V C W A V W L N N V T N Y F V V S L A A A D I A V G V L A I P F A I T I S T G A C H G C L F I A C F V L V L T Q S S I F S L L A I A I D R Y I A I R I T G T R A K G I I A I C W V L S F A I G L T P M L G P M N Y M V Y F N F F A C V L V P L L L M L G V Y L R I F L A A R R Q L K Q M E S E R A R S T L Q K E V H A A K S L A I I V G L F A L C W L P L H I I N C F T F F C P L W L M Y L A I V L S H T N S V V N P F I Y A Y R I R E F R K H V L P F F R Q T I I R S R Q Q E
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Residue Table


GPCRdb(A)
GPCRdb(A)
A2A receptor
TM3
3x33 3.33x33 L85
ECL2
45x52 45.52x52 F168
TM5
5x40 5.38x40 M177
TM6
6x48 6.48x48 W246
6x51 6.51x51 L249
6x52 6.52x52 H250
6x55 6.55x55 N253
TM7
7x34 7.35x34 M270