Structure information

A2A receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5N2R

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

A

PUBLICATION DATE

July 26, 2017

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
PSB36 V84 3.32x32 TM3 hydrophobic
PSB36 F168 45.52x52 ECL2 aromatic (face-to-face)
PSB36 M174 5.35x37 TM5 hydrophobic
PSB36 W246 6.48x48 TM6 hydrophobic
PSB36 L249 6.51x51 TM6 hydrophobic
PSB36 N253 6.55x55 TM6 polar (hydrogen bond)
PSB36 N253 6.55x55 TM6 polar (hydrogen bond)
PSB36 M270 7.35x34 TM7 hydrophobic
PSB36 I274 7.39x38 TM7 hydrophobic

Ligands

PSB36

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Residue Diagrams

V N G L I A L V A I A L E V T I Y V S S 1 V S L A A A D I A V G L V A I P F A I T I 2 A L L S F I S S Q T L V L V F C A I F L 3 A K G I I A I C W V L S F A I G L T P M 4 Y V G L M L L L P V L V C A F F N F Y V M Y 5 A I I V G L F A L C W L P L H I I N C F 6 F P N V V S N T H S L V I A L Y M L W 7
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ICL1 S N L Q ICL1ECL1 F C A ECL1ICL2 P L R Y N G L V ICL2ECL2 W N N C G Q P K E G K N H S Q G C G E G Q V A C L F E D V V ECL2ICL3 Q P L P G ICL3ECL3 P D C S H A ECL3C-term K A A G T S A R V L A A H G S D G E Q V S L R L N G H P P G V W A N G S A P H P E R R P N G Y A L G L V S G G S A Q E S Q G N T G L P D V E L L S H E L K G V C P E P P G L D D P L A Q D G A G V S C-term M P I M G S S V Y I T V E L A I A V L A I L G N V L V C W A V W L N N V T N Y F V V S L A A A D I A V G V L A I P F A I T I S T G A C H G C L F I A C F V L V L T Q S S I F S L L A I A I D R Y I A I R I T G T R A K G I I A I C W V L S F A I G L T P M L G P M N Y M V Y F N F F A C V L V P L L L M L G V Y L R I F L A A R R Q L K Q M E S E R A R S T L Q K E V H A A K S L A I I V G L F A L C W L P L H I I N C F T F F C P L W L M Y L A I V L S H T N S V V N P F I Y A Y R I R E F R K H V L P F F R Q T I I R S R Q Q E
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Residue Table


GPCRdb(A)
GPCRdb(A)
A2A receptor
TM3
3x32 3.32x32 V84
ECL2
45x52 45.52x52 F168
TM5
5x37 5.35x37 M174
TM6
6x48 6.48x48 W246
6x51 6.51x51 L249
6x55 6.55x55 N253
TM7
7x34 7.35x34 M270
7x38 7.39x38 I274