Structure information

A2A receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5OLH

SPECIES

Homo sapiens

RESOLUTION

2.600

PREFERRED CHAIN

A

PUBLICATION DATE

Jan. 17, 2018

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Vipadenant Y9 1.35x35 TM1 polar (hydrogen bond)
Vipadenant I66 2.64x63 TM2 hydrophobic
Vipadenant F168 45.52x52 ECL2 aromatic (face-to-face)
Vipadenant E169 ECL2 polar (charge-assisted hydrogen bond)
Vipadenant M177 5.38x40 TM5 hydrophobic
Vipadenant W246 6.48x48 TM6 hydrophobic
Vipadenant L249 6.51x51 TM6 hydrophobic
Vipadenant H250 6.52x52 TM6 aromatic (face-to-edge)
Vipadenant N253 6.55x55 TM6 polar (hydrogen bond)
Vipadenant N253 6.55x55 TM6 polar (hydrogen bond)
Vipadenant N253 6.55x55 TM6 polar (hydrogen bond)
Vipadenant I274 7.39x38 TM7 hydrophobic

Ligands

Vipadenant

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.

2D interaction plot

PoseView coming soon.

Residue Diagrams

V N G L I A L V A I A L E V T I Y V S S 1 V S L A A A D I A V G L V A I P F A I T I 2 A L L S F I S S Q T L V L V F C A I F L 3 A K G I I A I C W V L S F A I G L T P M 4 Y V G L M L L L P V L V C A F F N F Y V M Y 5 A I I V G L F A L C W L P L H I I N C F 6 F P N V V S N T H S L V I A L Y M L W 7
Download: PNG | SVG
ICL1 S N L Q ICL1ECL1 F C A ECL1ICL2 P L R Y N G L V ICL2ECL2 W N N C G Q P K E G K N H S Q G C G E G Q V A C L F E D V V ECL2ICL3 Q P L P G ICL3ECL3 P D C S H A ECL3C-term K A A G T S A R V L A A H G S D G E Q V S L R L N G H P P G V W A N G S A P H P E R R P N G Y A L G L V S G G S A Q E S Q G N T G L P D V E L L S H E L K G V C P E P P G L D D P L A Q D G A G V S C-term M P I M G S S V Y I T V E L A I A V L A I L G N V L V C W A V W L N N V T N Y F V V S L A A A D I A V G V L A I P F A I T I S T G A C H G C L F I A C F V L V L T Q S S I F S L L A I A I D R Y I A I R I T G T R A K G I I A I C W V L S F A I G L T P M L G P M N Y M V Y F N F F A C V L V P L L L M L G V Y L R I F L A A R R Q L K Q M E S E R A R S T L Q K E V H A A K S L A I I V G L F A L C W L P L H I I N C F T F F C P L W L M Y L A I V L S H T N S V V N P F I Y A Y R I R E F R K H V L P F F R Q T I I R S R Q Q E
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
A2A receptor
TM1
1x35 1.35x35 Y9
TM2
2x63 2.64x63 I66
ECL2
45x52 45.52x52 F168
TM5
5x40 5.38x40 M177
TM6
6x48 6.48x48 W246
6x51 6.51x51 L249
6x52 6.52x52 H250
6x55 6.55x55 N253
TM7
7x38 7.39x38 I274