Structure information

NTS1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6OS9

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

R

PUBLICATION DATE

July 10, 2019

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
JMV449 L54 N-term polar (hydrogen bond with backbone)
JMV449 F127 2.65x64 TM2 hydrophobic
JMV449 H131 ECL1 polar (hydrogen bond with backbone)
JMV449 Y145 3.29x29 TM3 polar (charge-assisted hydrogen bond)
JMV449 M207 ECL2 hydrophobic
JMV449 V223 ECL2 hydrophobic
JMV449 T225 45.51x51 ECL2 polar (hydrogen bond)
JMV449 I237 5.39x40 TM5 hydrophobic
JMV449 F326 6.58x58 TM6 hydrophobic
JMV449 W334 ECL3 hydrophobic
JMV449 Y339 7.28x27 TM7 hydrophobic
JMV449 Y342 7.31x30 TM7 polar (hydrogen bond)

Ligands

JMV449

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Residue Diagrams

T N G V T G V V F L A L Y V A T V L V K 1 G S L A L S D L L T L L L A M P V E L Y N 2 S A V N L A T A Y T C A D R L F Y Y G R 3 T K K F I S A I W L A S A L L A V P M 4 N L V S I V V M P F I F S M F T N V Q I V 5 R A V V I A F V V C W L P Y H V R R L M 6 I P N I T S S V Y F L A N T V M Y F Y 7
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ICL1 K S L Q ICL1ECL1 H H P W A F ECL1ICL2 P F K A K T L M ICL2ECL2 G E Q N R S A D G Q H A G G L V C T P T I ECL2ICL3 Q V C T V G G E H S T F S M A I E ICL3ECL3 S D E Q W ECL3N-term M R L N S S A P G T P G T P A A D P F Q R A Q A G L E E A L L A P G F G N A S G N A S E R V L A A P S S E L D V N T N-termC-term P V W R R R R K R P A F S R K A D S V S S N H T L S S N A T R E T L Y C-term D I Y S K V L V T A V Y L A L F V V G T V G N T V T A F T L A R K S L Q S T V H Y H L G S L A L S D L L T L L L A M P V E L Y N F I W V G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H S R S R T K K F I S A I W L A S A L L A V P M L F T M H T A T V K V V I Q V N T F M S F I F P M V V I S V L N T I I A N K L T V M V R Q A A E Q G P G R V Q A L R H G V R V L R A V V I A F V V C W L P Y H V R R L M F C Y I T P F L Y D F Y H Y F Y M V T N A L F Y V S S T I N P I L Y N L V S A N F L A L C F R H I T L A C
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Residue Table


GPCRdb(A)
GPCRdb(A)
NTS1 receptor
TM2
2x64 2.65x64 F127
TM3
3x29 3.29x29 Y145
ECL2
45x51 45.51x51 T225
TM5
5x40 5.39x40 I237
TM6
6x58 6.58x58 F326
TM7
7x27 7.28x27 Y339
7x30 7.31x30 Y342