Structure information

glucagon receptor

PROTEIN CLASS

Class B1 (Secretin)

PDB CODE

6WHC

SPECIES

Homo sapiens

RESOLUTION

3.400

PREFERRED CHAIN

R

PUBLICATION DATE

May 27, 2020

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Dual-agonist peptide P15 Q27 N-term polar (charge-assisted hydrogen bond)
Dual-agonist peptide P15 Q27 N-term polar (hydrogen bond with backbone)
Dual-agonist peptide P15 V28 N-term polar (hydrogen bond with backbone)
Dual-agonist peptide P15 M29 N-term polar (hydrogen bond with backbone)
Dual-agonist peptide P15 L32 N-term hydrophobic
Dual-agonist peptide P15 W36 N-term aromatic (face-to-edge)
Dual-agonist peptide P15 D63 N-term polar (hydrogen bond with backbone)
Dual-agonist peptide P15 Y65 N-term hydrophobic
Dual-agonist peptide P15 Y138 1.36x36 TM1 aromatic (face-to-face)
Dual-agonist peptide P15 Y145 1.43x43 TM1 aromatic (face-to-edge)
Dual-agonist peptide P15 Y149 1.47x47 TM1 polar (hydrogen bond)
Dual-agonist peptide P15 Q293 ECL2 polar (charge-assisted hydrogen bond)
Dual-agonist peptide P15 T296 45.52x52 ECL2 polar (hydrogen bond)
Dual-agonist peptide P15 S297 ECL2 polar (hydrogen bond)
Dual-agonist peptide P15 N298 ECL2 polar (hydrogen bond with backbone)
Dual-agonist peptide P15 W304 5.36x37 TM5 hydrophobic
Dual-agonist peptide P15 L386 7.43x42 TM7 hydrophobic

Ligands

Dual-agonist peptide P15

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

L L A G L S L S Y G V T Y M V Q F S S Y 1 A N L F A S F V L K A S S V L V I D G L 2 V L L W C Y N A V I G Y Q M F V A A V R 3 F F S L Y L G G I W G A P M L F V V P W A 4 F I F F N I L I A L F V P F R L I W W 5 L T L I P L L G V H E V V F A F V T D 6 V A V L L G Q F S S L F L D F F L K A 7
Download: PNG | SVG
ICL1 S K L H ICL1ECL1 Q K I G D D L S V S T W L S D G ECL1ICL2 A T L P E R ICL2ECL2 N V Q C W T S N D N M G F ECL2ICL3 R Q M H H T ICL3ECL3 E H A Q ECL3N-term M P P C Q P Q R P L L L L L L L L A C Q P Q V P S A Q V M D F L F E K W K L Y G D Q C H H N L S L L P P P T E L V C N R T F D K Y S C W P D T P A N T T A N I S C P W Y L P W H H K V Q H R F V F K R C G P D G Q W V R G P R G Q P W R D A S Q C Q M D G E E I E V N-termC-term T S N H R A S S S P G H G P P S K E L Q F G R G G G S Q D S S A E T P L A G G L P R L A E S P F C-term Q K E V A K M Y S S F Q V M Y T V G Y S L S L G A L L L A L A I L G G L C T R N A I H A N L F A S F V L K A S S V L V I D G L L R T R Y S A V A G C R V A A V F M Q Y G I V A N Y C W L L V E G L Y L H N L L G L S F F S L Y L G I G W G A P M L F V V P W A V V K C L F E W W I L R F P V F L A I L I N F F I F V R I V Q L L V A K L R A D Y K F R L A K S T L T L I P L L G V H E V V F A F V T D G T L R S A K L F F D L F L S S F Q G L L V A V L Y C F L N K E L R R W R L W E E V Q S E R W H R G K V L R N
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(B)
glucagon receptor
TM1
1x32 1.36x36 Y138
1x39 1.43x43 Y145
1x43 1.47x47 Y149
ECL2
45x52 45.52x52 T296
TM5
5x41 5.36x37 W304
TM7
7x38 7.43x42 L386