Structure information

SMO

PROTEIN CLASS

Class F (Frizzled)

PDB CODE

6XBK

SPECIES

Homo sapiens

RESOLUTION

3.240

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

Sept. 30, 2020
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Cholesterol F391 45.51x51 ECL2 hydrophobic
Cholesterol Y394 ECL2 hydrophobic
Cholesterol I408 5.51x51 TM5 hydrophobic
Cholesterol M525 7.45x45 TM7 hydrophobic
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 4 of 4 entries

Ligands

Cholesterol

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Residue Diagrams

L T C L G T V A G F A A I Y S H M D Q H 1 F Y V N A C F F V G S I G W L A Q F 2 V V F W V V G A M L A Y Y V I V F I I V 3 T S Y F H L L T W S L P F V L T V A I L 4 L F Y G G V I L V L G I P A L V F G A R Y 5 G I F G F L A F G F V L I T F S C H F Y 6 T S M A I G T G F M A F L N I K E V L L 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term T E A E H Q D M H S Y I A A F G A V T G L C T L F T L A T F V A D R Y P A V I L F Y V N A C F F V G S I G W L A Q F L S C V I I F V I V Y Y A L M A G V V W F V V L T Y A W H T S F K A K T S Y F H L L T W S L P F V L T V A I L A V A N Y R Y R A G F V L A P I G L V L I V G G Y F L I R G V M T L F S I K S N H S E K A A S K I N E T M L R L G I F G F L A F G F V L I T F S C H F Y D F F N Q A E W E R S F R D Y V L C Q A N V T I S L L V E K I N L F A M F G T G I A M S T W V W T K A W R R L T T L L I T W C R
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Residue Table


GPCRdb(A)
GPCRdb(F)
SMO
ECL2
45x51 45.51x51 F391
TM5
5x47 5.51x51 I408
TM7
7x42 7.45x45 M525