Structure information

ADGRG3

PROTEIN CLASS

Class B2 (Adhesion)

PDB CODE

7D77

SPECIES

Homo sapiens

RESOLUTION

2.900

PREFERRED CHAIN

R

REFERENCE

10.1038/S41586-020-03083-W

PUBLICATION DATE

Feb. 3, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
HYDROCORTISONE F323 2.64x64 TM2 hydrophobic
HYDROCORTISONE F345 3.36x36 TM3 hydrophobic
HYDROCORTISONE W421 45.51x51 ECL2 hydrophobic
HYDROCORTISONE W490 6.53x53 TM6 hydrophobic
HYDROCORTISONE L498 ECL3 hydrophobic

Ligands

HYDROCORTISONE

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Residue Diagrams

A L F I M S V G C G A Q S I R T L I H V 1 V A L G G S L F L L N L A F L V N V G S 2 L G M W T F A C L L F Y H F V A G R A W 3 Y F L K L S L G V W G L P A L M V I G T G 4 L V V M G F L F T I L F Y G H V T I Y L A 5 L G L S S L V G V T W G L A I F 6 C C I F V G Q L S N F L A F I Y V T 7
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ICL1 E R F K S ICL1ECL1 G S K G ECL1ICL2 V F N T Y F G ICL2ECL2 S Y G L Y T I R D R E N R T S L E L C W F R E G T T M ECL2ICL3 A V K E R G ICL3ECL3 T P L G L S ECL3N-term M A T P R G L G A L L L L L L L P T S G Q E K P T E G P R N T C L G S N N M Y D N-termC-term L P S Q S T T V S S S T A R L D Q A H S A S Q E C-term D Q S T V H I L T R I S Q A G C G V S M I F L A F T I I L Y A F L R L S R E D A P K I H V A L G G S L F L L N L A F L V N V G S S D A A C W A R G A V F H Y F L L C A F T W M G L E A F H L Y L L A V R H Y F L K L S L V G W G L P A L M V I G T G S A N Y A L Y I T V H G Y F L I T F L F G M V V L A L V V W K I F T L S R A T K N R K K V L T L L G L S S L V G V T W G L A I F T V Y I F A L F N S L Q G V F I C C W F T I L Y
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Residue Table


GPCRdb(A)
GPCRdb(B)
ADGRG3
TM2
2x57 2.64x64 F323
TM3
3x32 3.36x36 F345
ECL2
45x51 45.51x51 W421
TM6
6x48 6.53x53 W490