Structure information

GAL1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7XJJ

SPECIES

Homo sapiens

RESOLUTION

3.300

PREFERRED CHAIN

E

REFERENCE

PUBLICATION DATE

May 3, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
galanin Q92 2.61x60 TM2 polar (hydrogen bond)
galanin Q92 2.61x60 TM2 polar (hydrogen bond)
galanin V95 2.64x63 TM2 Van der Waals
galanin V95 2.64x63 TM2 hydrophobic
galanin Y96 2.65x64 TM2 Van der Waals
galanin L98 2.67x66 TM2 Van der Waals
galanin P99 ECL1 polar (hydrogen bond with backbone)
galanin P99 ECL1 Van der Waals
galanin T100 23.49x49 ECL1 Van der Waals
galanin H112 3.29x29 TM3 Van der Waals
galanin H112 3.29x29 TM3 aromatic (face-to-edge)
galanin H112 3.29x29 TM3 polar (hydrogen bond)
galanin F186 ECL2 Van der Waals
galanin F186 ECL2 hydrophobic
galanin C187 45.50x50 ECL2 Van der Waals
galanin W188 45.51x51 ECL2 polar (hydrogen bond)
galanin V274 ECL3 hydrophobic
galanin F275 ECL3 hydrophobic
galanin F275 ECL3 Van der Waals
galanin L277 ECL3 hydrophobic
galanin L277 ECL3 Van der Waals
galanin T278 7.28x27 TM7 polar (hydrogen bond with backbone)
galanin T278 7.28x27 TM7 Van der Waals
galanin S281 7.31x30 TM7 polar (hydrogen bond)
galanin F282 7.32x31 TM7 polar (hydrogen bond with backbone)
galanin F282 7.32x31 TM7 Van der Waals
galanin R285 7.35x34 TM7 Van der Waals

Ligands

galanin

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Residue Diagrams

S N G L V G L A F I L G F V V L T V F N 1 L N L S I A D L A Y L F L C I P F Q A T V 2 A A L T F I S V L M S V T F F Y H I F K 3 A L L G V G C I W A L S I A M A S P V 4 Y C F C I L L L P L L Y G F V F T C V V Y 5 L V V V V V F G I S W L P H H I I H L W 6 I P N V S S N S Y A L C H A T I R F L 7
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ICL1 K P G K P R ICL1ECL1 P T W V L ECL1ICL2 S R R S S S L R ICL2ECL2 G L F H P R A S N Q T F C W E Q W P ECL2ICL3 K N M ICL3ECL3 V F P L ECL3N-term M E L A V G N L S E G N A S W P E P P A P E P G P L F G I N-termC-term C H I R K D S H L S D T K E S K S R I D T P P S T N C T H V C-term G V E N F V T L V V F G L I F A L G V L G N S L V I T V L A R S S T T N L F I L N L S I A D L A Y L L F C I P F Q A T V Y A L G A F I C K F I H Y F F T V S M L V S I F T L A A M S V D R Y V A I V H V S R N A L L G V G C I W A L S I A M A S P V A Y H Q D P R H K K A Y V V C T F V F G Y L L P L L L I C F C Y A K V L N H L H K K L S K K S E A S K K K T A Q T V L V V V V V F G I S W L P H H I I H L W A E F G T P A S F L F R I T A H C L A Y S N S S V N P I I Y A F L S E N Y K Q F R K A V F K
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Residue Table


GPCRdb(A)
GPCRdb(A)
GAL1 receptor
TM2
2x60 2.61x60 Q92
2x63 2.64x63 V95
2x64 2.65x64 Y96
2x66 2.67x66 L98
ECL1
23x49 23.49x49 T100
TM3
3x29 3.29x29 H112
ECL2
45x50 45.50x50 C187
45x51 45.51x51 W188
TM7
7x27 7.28x27 T278
7x30 7.31x30 S281
7x31 7.32x31 F282
7x34 7.35x34 R285