PDB
7YK7
Resolution
2.8 Å
Released
March 1, 2023
Receptor
RXFP4
Class
A
Species
Homo sapiens
Ligand
DC591053
Function
Agonist
Reference
10.1038/S41467-023-36182-Z

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
DC591053 W97 2.60x60 TM2 hydrophobic
DC591053 F105 ECL1 hydrophobic
DC591053 L118 3.29x29 TM3 hydrophobic
DC591053 L192 45.51x51 ECL2 hydrophobic
DC591053 L193 45.52x52 ECL2 hydrophobic
DC591053 Y204 5.38x39 TM5 hydrophobic
DC591053 R208 5.42x43 TM5 polar (charge-assisted hydrogen bond)
DC591053 F291 7.35x34 TM7 hydrophobic
DC591053 F291 7.35x34 TM7 Van der Waals
DC591053 T295 7.39x38 TM7 polar (hydrogen bond)
DC591053 T295 7.39x38 TM7 Van der Waals
DC591053 H299 7.43x42 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R A R A P ICL1ECL1 F H W P F ECL1ICL2 A A G P G T H L ICL2ECL2 V E G E V C G V R L C L L R F P S R ECL2ICL3 Q R ICL3ECL3 V P W N S ECL3N-term M P T L N T S A S P P T F F W A N A S G G S V L S A D D A P M P V K N-termC-term L R L R L W P Q G G G W V Q Q V A L K Q V G R R W V A S N P R E S R P S T L L T N L D R G T P G C-term F L A L R L M V A L A Y G L V G A I G L L G N L A V L W V L S N C G P P S D T F V F N L A L A D L G L A L T L P F W A A E S A L D G G A L C K M V L T A T V L N V Y A S I F L I T A L S V A R Y W V V A M S L F W A R I A T L A V W A A A A L V T V P T A V F G Y W L G A Y Q L Q R V V L A F M V P L G V I T T S Y L L L L A F L Q R R R R Q D S R V V A R S V R I L V A S F F L C W F P N H V V T L W G V L V K F D L T F Y T I Q T Y V F P V T T C L A H S N S C L N P V L Y C L L R R E L A G P R Q A T F R D
Helix box plot — Download: PNG | SVG L N G L L G I A G V L G Y A L A V M L R 1 F N L A L A D L G L A L T L P F W A A E 2 A T I L F I S A Y V N L V T A T L V M K 3 A R I A T L A V W A A A A L V T V P T 4 Y S T T I V G L P V M F A L V V R Q L Q Y 5 R I L V A S F F L C W F P N H V V T L W 6 V P N L C S N S H A L C T T V P F V Y 7

GPCRdb(A)
GPCRdb(A)
RXFP4
TM2
2x60 2.60x60 W97
TM3
3x29 3.29x29 L118
ECL2
45x51 45.51x51 L192
45x52 45.52x52 L193
TM5
5x39 5.38x39 Y204
5x43 5.42x43 R208
TM7
7x34 7.35x34 F291
7x38 7.39x38 T295
7x42 7.43x42 H299