Structure information

FFA1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8EIT

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

R

REFERENCE

10.1073/PNAS.2219569120

PUBLICATION DATE

May 24, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
docosahexaenoic acid V84 3.30x30 TM3 hydrophobic
docosahexaenoic acid F87 3.33x33 TM3 hydrophobic
docosahexaenoic acid F142 4.61x61 TM4 hydrophobic
docosahexaenoic acid R183 5.39x40 TM5 polar (charge-assisted hydrogen bond)
docosahexaenoic acid L186 5.42x43 TM5 hydrophobic
docosahexaenoic acid L186 5.42x43 TM5 Van der Waals

Ligands

docosahexaenoic acid

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Residue Diagrams

V N L P F G L A F A A V Y L G F S L Q P 1 L N L G C S D L L L T V S L P L K A V E 2 A A L F G G G A Y L P F F H A V A F V P 3 S W G V C A A I W A L V L C H L G L V F 4 Y C F A T I A L P L F F L L L S L S F R A 5 A G G A L L T L L L C V G P Y N A S N V A 6 L P N L V V S W A G T I L G L K R W S 7
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ICL1 L ICL1ECL1 G A W P L ECL1ICL2 P L G Y Q A F R ICL2ECL2 P G G W L D H S N T S L G I N T P V N G S P V C L E A W ECL2ICL3 S G L T H ICL3ECL3 P N L G ECL3N-term M D L N-termC-term G G K S Q K C-term P P Q L S F G L Y V A A F A L G F P L N V L A I R G A T A H A R L R T P S L V Y A L N L G C S D L L L T V S L P L K A V E A L A S P A S L C P V F A V A H F F P L Y A G G G F L A A L S A G R Y L G A A F R P C Y S W G V C A A I W A L V L C H L G L V F G L E A D P A S A G P A R F S L S L L L F F L P L A I T A F C Y V G C L R A L A R R R K L R A A W V A G G A L L T L L L C V G P Y N A S N V A S F L Y G S W R K L G L I T G A W S V V L N P L V T G Y L G R G T V C Q P G L K A A R T
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Residue Table


GPCRdb(A)
GPCRdb(A)
FFA1 receptor
TM3
3x30 3.30x30 V84
3x33 3.33x33 F87
TM4
4x61 4.61x61 F142
TM5
5x40 5.39x40 R183
5x43 5.42x43 L186