Structure information

GPR34

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8IYX

SPECIES

Homo sapiens

RESOLUTION

3.340

PREFERRED CHAIN

C

REFERENCE

10.1073/PNAS.2308435120

PUBLICATION DATE

March 20, 2024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
YL-365 Y135 3.33x33 TM3 hydrophobic
YL-365 Y139 3.37x37 TM3 hydrophobic
YL-365 I143 3.41x41 TM3 hydrophobic
YL-365 F147 3.45x45 TM3 hydrophobic
YL-365 L181 4.52x52 TM4 hydrophobic
YL-365 A182 4.53x53 TM4 hydrophobic
YL-365 G185 4.56x56 TM4 polar (hydrogen bond with backbone)
YL-365 G185 4.56x56 TM4 Van der Waals
YL-365 M189 4.60x60 TM4 hydrophobic
YL-365 M189 4.60x60 TM4 Van der Waals

Ligands

YL-365

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

I N G V L G V I F I V S Y S T T L V T S 1 L N V A I A D L L L I F C L P F R I M Y 2 F G L L I I S I Y M N M Y F L T G V V K 3 S I Y V C C I V W M L A L G G F L T M I 4 Y S L I I L L F I L W F M V V L I F N F 5 S F I V L I I F I T C F V P Y H A F R F I 6 V P D L C S N F S S L V L M I E N T K 7
Download: PNG | SVG
ICL1 R K R ICL1ECL1 N K W T L ECL1ICL2 I Q Q R K A I T T ICL2ECL2 G H N S T M C F H Y R D K H N A ECL2ICL3 R R S K F P N ICL3ECL3 Q L N V S ECL3N-term M R S H T I T M T T T S V S S W P Y S S H R M R F I T N H S D Q P P Q N F S A T P N V T T C P M D E K N-termC-term G E P S R S E S T S E F K P G Y S L H D T S V A V K I Q S S S K S T C-term L L S T V L T T S Y S V I F I V G L V G N I I A L Y V F L G I H N S I Q I Y L L N V A I A D L L L I F C L P F R I M Y H I N Q G V I L C K V V G T L F Y M N M Y I S I I L L G F I S L D R Y I K I N R S K Q S I Y V C C I V W M L A L G G F L T M I I L T L K K G K G E A I F N F I L V V M F W L I F L L I I L S Y I K I G K N L L R I S K S G K Y A T T A R N S F I V L I I F T I C F V P Y H A F R F I Y I S S S C Y W K E I V H K T N E I M L V L S S F N S C L D P V M Y F L M S S N M C Q R F Q I R K I L L F R
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
GPR34
TM3
3x33 3.33x33 Y135
3x37 3.37x37 Y139
3x41 3.41x41 I143
3x45 3.45x45 F147
TM4
4x52 4.52x52 L181
4x53 4.53x53 A182
4x56 4.56x56 G185
4x60 4.60x60 M189